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Sequence NM_177996
GTGCCTGACTGACAGAAGTTCTTGCCCCCGGGGAGCTGGTGTGGACAGAGGAGGGAGCCTAGACATGGAGGAGAAGGACTACAGTGAGGCCGATGGCCTTTCGGAGAGGACCACGCCCAGCAAGGCCCAGAAATCGCCCCAGAAGATTGCCAAGAAATACAAGAGTGCCATCTGCCGGGTCACTCTGCTTGATGCCTCGG
AGTATGAGTGTGAGGTGGAGAAACATGGCCGGGGCCAGGTGCTGTTTGACCTGGTCTGTGAACACCTCAACCTCCTAGAGAAGGACTACTTCGGCCTGAC
CTTCTGTGATGCTGACAGCCAGAAGAACTGGCTGGACCCCTCCAAGGAGATCAAGAAGCAGATCCGGAGTAGCCCCTGGAATTTTGCCTTCACAGTCAAG
TTCTACCCGCCTGATCCTGCCCAGCTGACAGAAGACATCACAAGATACTACCTGTGCCTGCAGCTGCGGGCAGACATCATCACGGGCCGGCTGCCATGCT
CCTTTGTCACGCATGCCCTACTGGGCTCCTACGCTGTGCAGGCTGAGCTGGGTGACTATGATGCTGAGGAGCATGTGGGCAACTATGTCAGCGAGCTCCG
CTTCGCCCCTAACCAGACCCGGGAGCTGGAGGAGAGGATCATGGAGCTGCATAAGACATATAGGGGGATGACCCCGGGAGAAGCAGAAATCCACTTCTTA
GAGAATGCCAAGAAGCTTTCCATGTACGGAGTAGACCTGCACCATGCCAAGGACTCTGAGGGCATCGACATCATGTTAGGCGTTTGTGCCAATGGCCTGC
TCATCTACCGGGACCGGCTGAGAATCAACCGCTTTGCCTGGCCCAAGATCCTCAAGATCTCCTACAAGAGGAGTAACTTCTATATCAAGATCCGGCCTGG
GGAGTATGAGCAATTTGAGAGCACAATTGGCTTTAAGCTCCCAAACCACCGGTCAGCCAAGAGACTGTGGAAGGTCTGCATCGAGCATCATACATTCTTC
CGGCTGGTGTCCCCTGAGCCCCCACCCAAGGGCTTCCTGGTGATGGGCTCCAAGTTCCGGTACAGTGGGAGGACCCAGGCACAGACTCGCCAGGCCAGCG
CCCTCATTGACCGGCCTGCACCCTTCTTTGAGCGTTCTTCCAGCAAACGGTACACCATGTCCCGCAGCCTTGATGGAGCAGAGTTCTCCCGCCCAGCCTC
GGTCAGCGAGAACCATGATGCAGGGCCTGACGGTGACAAGCGGGATGAGGATGGCGAGTCTGGGGGGCAACGGTCAGAGGCTGAGGAGGGAGAGGTCAGG
ACTCCAACCAAGATCAAGGAGCTAAAGTTCTTAGACAAGCCAGAAGATGTCTTGCTGAAGCACCAGGCCAGCATCAATGAGCTCAAAAGGACCCTGAAGG
AGCCCAACAGCAAACTCATCCACCGGGATCGAGACTGGGAACGGGAGCGCAGGCTGCCCTCCTCCCCCGCCTCCCCCTCCCCCAAGGGCACCCCTGAGAA
AGCCAATGAGAGAGCAGGGCTGAGGGAGGGCTCCGAGGAGAAAGTCAAACCACCACGTCCCCGGGCCCCAGAGAGTGACACAGGCGATGAGGACCAGGAC
CAGGAGAGGGACACGGTGTTCCTGAAGGACAACCACCTGGCCATTGAGCGCAAGTGCTCCAGCATCACGGTCAGCTCTACGTCTAGCCTGGAGGCTGAGG
TGGACTTCACGGTCATTGGTGACTACCATGGCAGCGCCTTCGAAGACTTCTCCCGCAGCCTGCCTGAGCTCGACCGGGACAAAAGCGACTCGGACACTGA
GGGCCTGCTGTTCTCCCGGGATCTCAACAAGGGGGCCCCCAGCCAGGATGATGAGTCTGGGGGCATTGAGGACAGCCCGGATCGAGGGGCCTGCTCCACC
CCGGATATGCCCCAGTTTGAGCCCGTGAAAACAGAAACCATGACTGTCAGCAGTCTGGCCATTAGAAAGAAGATTGAGCCGGAGGCCGTACTGCAGACCA
GAGTCTCCGCTATGGATAACACCCAGGAGAACAGTCTCAAGTCCGGGAAGGGGGCAGCTGCCATGATCCCAGGCCCACAGACGGTGGCCACGGAAATCCG
TTCTCTTTCTCCGATCATCGGGAAAGATGTCCTCACCAGCACCTACGGCGCCACTGCGGAAACCCTCTCAACCTCCACCACCACCCATGTCACCAAAACT
GTGAAAGGAGGGTTTTCTGAGACAAGGATCGAGAAGCGAATCATCATTACTGGGGATGAAGATGTCGATCAAGACCAGGCCCTGGCTTTGGCCATCAAGG
AGGCCAAACTGCAGCATCCTGATATGCTGGTAACCAAAGCTGTCGTATACAGAGAAACAGACCCATCCCCAGAGGAGAGGGACAAGAAGCCACAGGAATC
CTGACCTCTGTGAAGAGATCCTGGCATTTCTGGTCCAACCCAAGCCAGAGAACCATTAAGAAGGGGCCTTCATTCTGGATTCTCCGACGCAACACTGACG
TCCCAGCTGCGACGTACTGTCACTGATGAGAGACTGGGAAGGGAAAAGCATATATATATAGATATATAGAGATATAGATATATATACAGGAAACACCGCA
TCCTTGCACTGCTGCTGGGGCTGGCAGAGCAGTTGGCTGACAGCAACAACCGACATCTGAACACCTACATTTCCTTTGCAGACAAATTGAAGAACTGGTG
GGATTTTTTTCAAGAAAAAAAATTATATAATAACTATAATCCCTTGCTCACCCCTTTCCCCCGCCAAATAAGAAACGCAAGCCAGACCACGATGATTGTA
GAAGTCCCTCCCGCCCTGGTTCTGCACGTTACAGTTAGCAGACGAGCAATTCCATTTGTTCTTCTCCAGCATCTCTAAGGCCCACTTGAATGCAAAGGAA
AACACTTGCACAGCAAAGCAAGAGAAGTCACAGCAGCAAGACACGCACAGTCAACCATTTTCCGAGAAAAAAAGAAAATTCCCCACTTGGAAAGAAAGAG
GAGGAACACTGGATTCTTACTTTCTGGATCTTGACACTGGGCTGCAAAACCTACCTTCCTCTCTCCCGCCTCCCCTCACCCTCAACTCTCAATGTCTTGC
TGTCATTTTCTGTCTCGGCTCCCTCCTCCCCCTTCCCCCTTCCCCCACCCCACACCCTTCACCCTCTGTGTCCTGGTCCTTCTGAGGGCCACTGCAGATG
ACTCTCCTTTGAAATGAGAAAAAGAAAAGAAAGCAAGAACAGAAAACGAAGCCACAGGAAGGGAAGTAGACATTGTATGCTTATGGTTTCTCATTATGAA
GGTGCAGCTTGTAGGAGGTTTGTACGGATGTGCTTTGAAGTTATGTATATTACATATAACAGGAAAAAATATTAAAATAAACAGTGCTGGTAAGTATGAA
GCTGACATTCTAAAATTATAATTATCTGACTGTGATTGATGTATCCTGAGGTTCCTAGATCTCACTGAACTGGCCCAGCTAAGGAGACCTGGACTCTGGG
TGTGGGTTGGCTCACAGTAGGGGCTGACGGGTTCAGTGTAGTAATACTGTGTGTGGTGTTTGTAATTGGTTGATTGGTGGGGAGGGGTGGGGGGCCCTAA
TGGAGAGGTGTGGGTTTGGCAAGAAAGAAGCAACACAGATGTCGTCCCCAAAATGCCAGTTCAAGACACCTTCTCCCTGCCCCCCTGGTAGTAACAGTCA
GGGCCTGGTCTGTGCTCAGGTACTGGGTCCCAGTCTGGGACTCTGCTGCTGAAGTTGCCACAGTAGAGGTCCCTGGCTTAGTCCTTATCTCCCTACGGGG
CTTGCCTTGGTTTTCAGTCTTCTCTCTCTTTCTCTCTTTTTTTTTTTTTTGCCACATTCTGCCCTTCCCTGACCCCATTGTAATAACCAACTCCATATCC
AAAGGGAGGTGGTGCTCTCAGCCATTGTAGAAGATGGTGGCTTTAACCTGACTGTCTAAAAATTCCCAGCTAAGCCTTTTCCTCTACTCTCTTCCTTGTT
CTGAATCATTTCTTCTTCTCAGGCCAAAGTAGCCATGGTAAGGAGGCTTCATGGGGCAGACCCTGAAAGATCAAAACTGCATTTGCAAAGCCCTCCCCTG
TCCCAGGACAAAGCTGAGACTGACGGGTGATGTTGCTCATAGGCTCCAGCTCTGCATAAGACCTTGGCTTGGAGACCTCCCTCTCAGTCAACAGCTGAAC
TCTGAGCTTGTGCCCAGAAATTACCCCAAGACCACAGGAACCCTTCAAGAAGCTCCCATCACAAGCTTGGCATTGCTCTCTGCCACACGTGGGCTTCCTC
AGGCTTGTCTGCCACAAGCTACTTCTCTGAGCTCAGAAAGTGCCCCTTGATGAGGGAAAATGTCCCACTGCACTGCGAATTTCTCAGTTCCATTTTACCT
CCCAGTCCTCCTTCTAAACCAGTTAATAAATTCATTCCACAAGTATTTACTGATTACCTGCTTGTGCCAGGGACTATTCTCAGGCTGAAGAAGGTGGGAG
GGGAGGGCGGAACCTGAGGAGCCACCTGAGCCAGCTTTATATTTCAACCATGGCTGGCCCATCTGAGAGCATCTCCCCACTCTCGCCAACCTATCGGGGC
ATAGCCCAGGGATGCCCCCAGGCGGCCCAGGTTAGATGCGTCCCTTTGGCTTGTCAGTGATGACATACACCTTAGCTGCTTAGCTGGTGCTGGCCTGAGG
CAGGGCAGGAAATCAGAATAGCATTTGCTTCTCTGGGCAAATGGGAAGTTCAGCGGGGCAGCAGAATCAGTGGCATTCCCCCTGGTGCAGGCCGGTGGGT
CCACTCCAACTCCCCCTGAGTGTAGCAGCACACTTTCCATACACCAGGTTCTTTCTACAATCCTGGTGGAAAAGCCACAGAACCTTCTTCCTGCCCTTCT
TGAGAGTTCCCCCTCTTTCTGGGTCAAGAGCTGGAGTGGTGGCTCCATCCTCTCTGGGCCACTTCGGTCTAGGAACTCATCTTTGCAGGAACCAGGAGTC
CTGAGCACACTGAACACACCTCAGAGGGAGGATCCTTGTTGTGGATTTTGCACCTGGCTTTGGGGCAGGGGTGAAGTGACCAGGCTTAGCTTGTGGAGTT
TATGGGCCACCAGGGTTTGGGGAAATCACCATCCCGCGGATGCTGTGACCTCCCTTCTACGGAGATGCAGGCAGTGCCACGAGGGAGGAGGGGACCTGCA
AAGCTAGAATCTAGGGCACTGTTTCCTCCCCATCCTTCTCTTTGTAGAGAATAGAGACGTTTGTCTTGTCTGTCTTCAACCTACTTTTCCTTTTCTCTTT
TTTGTTTCTCATCCTCTCTGTGCCACCTCTCCACCCAGGAGGCCATGTAGCATAGTGGAAAAAGTCCCTGAGGGCGGTTAGGAGTTCTGGGTGACCATCC
TGGCTCAGCTCCTAACTCACCATGTGACATCAGGCTATCCCCATTCCCCCTCTTGGGCCTCAGTTTCCCGACTTGCAAAATAAGCAGAAAGAACCAGATG
CTCTCCAGGGTCTTTTTCTACTTTGCTATCTCATGGGTCTTCATTTTCTCTTATTTTGTTTTCTCTGGATCTTTTCCATCTGAGGGTACAGGAAGTACCA
GGACCTGTTTCAGTTTTTGAATCCTGCAAGCACATTCCAAGACTGGCCTGAAACTGCATGAGCAACATCACTCGAAATAATTTTTTTTTTCAAAAGCACC
TTAACAACCAATTGCGATGCTGTCCTGTTCCTTTTTACTCACACCCTTCTCTCCTTTCTCGTCCCCATGCTCCCCCACCTCAGTGCTCCGTGCTGTATGC
GTGTGCTCTCTGTTCTTGTATACTCAATATAAGTGAAATAAATGTGTTTGATGCTGAACCATA
- refseq_EPB41L1.F3 (forward primer)
- refseq_EPB41L1.R3 (reverse primer)
- Single exon skipping
Frame 0
VPD*QKFLPPGSWCGQRREPRHGGEGLQ*GRWPFGEDHAQQGPEIAPEDCQEIQECHLPGHSA*CLG
V*V*GGETWPGPGAV*PGL*TPQPPREGLLRPD
LL*C*QPEELAGPLQGDQEADPE*PLEFCLHSQ
VLPA*SCPADRRHHKILPVPAAAGRHHHGPAAML
LCHACPTGLLRCAG*AG*L*C*GACGQLCQRAP
LRP*PDPGAGGEDHGAA*DI*GDDPGRSRNPLL
RECQEAFHVRSRPAPCQGL*GHRHHVRRLCQWPA
HLPGPAENQPLCLAQDPQDLLQEE*LLYQDPAW
GV*AI*EHNWL*APKPPVSQETVEGLHRASYIL
PAGVP*APTQGLPGDGLQVPVQWEDPGTDSPGQR
PH*PACTLL*AFFQQTVHHVPQP*WSRVLPPSL
GQREP*CRA*R*QAG*GWRVWGATVRG*GGRGQ
DSNQDQGAKVLRQARRCLAEAPGQHQ*AQKDPEG
AQQQTHPPGSRLGTGAQAALLPRLPLPQGHP*E
SQ*ESRAEGGLRGESQTTTSPGPRE*HRR*GPG
PGEGHGVPEGQPPGH*AQVLQHHGQLYV*PGG*G
GLHGHW*LPWQRLRRLLPQPA*ARPGQKRLGH*
GPAVLPGSQQGGPQPG**VWGH*GQPGSRGLLH
PGYAPV*ARENRNHDCQQSGH*KED*AGGRTADQ
SLRYG*HPGEQSQVREGGSCHDPRPTDGGHGNP
FSFSDHRERCPHQHLRRHCGNPLNLHHHPCHQN
CERRVF*DKDREANHHYWG*RCRSRPGPGFGHQG
GQTAAS*YAGNQSCRIQRNRPIPRGEGQEATGI
LTSVKRSWHFWSNPSQRTIKKGPSFWILRRNTD
VPAATYCH**ETGKGKAYIYRYIEI*IYIQETPH
PCTAAGAGRAVG*QQQPTSEHLHFLCRQIEELV
GFFSRKKII**L*SLAHPFPPPNKKRKPDHDDC
RSPSRPGSARYS*QTSNSICSSPASLRPT*MQRK
TLAQQSKRSHSSKTRTVNHFPRKKENSPLGKKE
EEHWILTFWILTLGCKTYLPLSRLPSPSTLNVL
LSFSVSAPSSPFPLPPPHTLHPLCPGPSEGHCR*
LSFEMRKRKESKNRKRSHRKGSRHCMLMVSHYE
GAACRRFVRMCFEVMYITYNRKKY*NKQCW*V*
S*HSKIIII*L*LMYPEVPRSH*TGPAKETWTLG
VGWLTVGADGFSVVILCVVFVIG*LVGRGGGP*
WRGVGLARKKQHRCRPQNASSRHLLPAPLVVTV
RAWSVLRYWVPVWDSAAEVATVEVPGLVLISLRG
LPWFSVFSLFLSFFFFCHILPFPDPIVITNSIS
KGRWCSQPL*KMVALT*LSKNSQLSLFLYSLPC
SESFLLLRPK*PW*GGFMGQTLKDQNCICKALPC
PRTKLRLTGDVAHRLQLCIRPWLGDLPLSQQLN
SELVPRNYPKTTGTLQEAPITSLALLSATRGLP
QACLPQATSLSSESAP**GKMSHCTANFSVPFYL
PVLLLNQLINSFHKYLLITCLCQGLFSG*RRWE
GRAEPEEPPEPALYFNHGWPI*EHLPTLANLSG
HSPGMPPGGPG*MRPFGLSVMTYTLAA*LVLA*G
RAGNQNSICFSGQMGSSAGQQNQWHSPWCRPVG
PLQLPLSVAAHFPYTRFFLQSWWKSHRTFFLPF
LRVPPLSGSRAGVVAPSSLGHFGLGTHLCRNQES
*AH*THLRGRILVVDFAPGFGAGVK*PGLACGV
YGPPGFGEITIPRML*PPFYGDAGSATREEGTC
KARI*GTVSSPSFSL*RIETFVLSVFNLLFLFSF
LFLILSVPPLHPGGHVA*WKKSLRAVRSSG*PS
WLSS*LTM*HQAIPIPPLGPQFPDLQNKQKEPD
ALQGLFLLCYLMGLHFLLFCFLWIFSI*GYRKYQ
DLFQFLNPASTFQDWPETA*ATSLEIIFFFKST
LTTNCDAVLFLFTHTLLSFLVPMLPHLSAPCCM
RVLSVLVYSI*VK*MCLMLNH
Frame 1
CLTDRSSCPRGAGVDRGGSLDMEEKDYSEADGLSERTTPSKAQKSPQKIAKKYKSAICRVTLLDAS
EYECEVEKHGRGQVLFDLVCEHLNLLEKDYFGLT
FCDADSQKNWLDPSKEIKKQIRSSPWNFAFTVK
FYPPDPAQLTEDITRYYLCLQLRADIITGRLPC
SFVTHALLGSYAVQAELGDYDAEEHVGNYVSELR
FAPNQTRELEERIMELHKTYRGMTPGEAEIHFL
ENAKKLSMYGVDLHHAKDSEGIDIMLGVCANGL
LIYRDRLRINRFAWPKILKISYKRSNFYIKIRPG
EYEQFESTIGFKLPNHRSAKRLWKVCIEHHTFF
RLVSPEPPPKGFLVMGSKFRYSGRTQAQTRQAS
ALIDRPAPFFERSSSKRYTMSRSLDGAEFSRPAS
VSENHDAGPDGDKRDEDGESGGQRSEAEEGEVR
TPTKIKELKFLDKPEDVLLKHQASINELKRTLK
EPNSKLIHRDRDWERERRLPSSPASPSPKGTPEK
ANERAGLREGSEEKVKPPRPRAPESDTGDEDQD
QERDTVFLKDNHLAIERKCSSITVSSTSSLEAE
VDFTVIGDYHGSAFEDFSRSLPELDRDKSDSDTE
GLLFSRDLNKGAPSQDDESGGIEDSPDRGACST
PDMPQFEPVKTETMTVSSLAIRKKIEPEAVLQT
RVSAMDNTQENSLKSGKGAAAMIPGPQTVATEIR
SLSPIIGKDVLTSTYGATAETLSTSTTTHVTKT
VKGGFSETRIEKRIIITGDEDVDQDQALALAIK
EAKLQHPDMLVTKAVVYRETDPSPEERDKKPQES
*PL*RDPGISGPTQAREPLRRGLHSGFSDATLT
SQLRRTVTDERLGREKHIYIDI*RYRYIYRKHR
ILALLLGLAEQLADSNNRHLNTYISFADKLKNWW
DFFQEKKLYNNYNPLLTPFPRQIRNASQTTMIV
EVPPALVLHVTVSRRAIPFVLLQHL*GPLECKG
KHLHSKAREVTAARHAQSTIFREKKKIPHLERKR
RNTGFLLSGS*HWAAKPTFLSPASPHPQLSMSC
CHFLSRLPPPPSPFPHPTPFTLCVLVLLRATAD
DSPLK*EKEKKARTENEATGREVDIVCLWFLIMK
VQLVGGLYGCALKLCILHITGKNIKINSAGKYE
ADILKL*LSDCD*CILRFLDLTELAQLRRPGLW
VWVGSQ*GLTGSV**YCVWCL*LVDWWGGVGGPN
GEVWVWQERSNTDVVPKMPVQDTFSLPPW**QS
GPGLCSGTGSQSGTLLLKLPQ*RSLA*SLSPYG
ACLGFQSSLSFSLFFFFATFCPSLTPL**PTPYP
KGGGALSHCRRWWL*PDCLKIPS*AFSSTLFLV
LNHFFFSGQSSHGKEASWGRP*KIKTAFAKPSP
VPGQS*D*RVMLLIGSSSA*DLGLETSLSVNS*T
LSLCPEITPRPQEPFKKLPSQAWHCSLPHVGFL
RLVCHKLLL*AQKVPLDEGKCPTALRISQFHFT
SQSSF*TS**IHSTSIY*LPACARDYSQAEEGGR
GGRNLRSHLSQLYISTMAGPSESISPLSPTYRG
IAQGCPQAAQVRCVPLACQ**HTP*LLSWCWPE
AGQEIRIAFASLGKWEVQRGSRISGIPPGAGRWV
HSNSP*V*QHTFHTPGSFYNPGGKATEPSSCPS
*EFPLFLGQELEWWLHPLWATSV*ELIFAGTRS
PEHTEHTSEGGSLLWILHLALGQG*SDQA*LVEF
MGHQGLGKSPSRGCCDLPSTEMQAVPRGRRGPA
KLESRALFPPHPSLCRE*RRLSCLSSTYFSFSL
FCFSSSLCHLSTQEAM*HSGKSP*GRLGVLGDHP
GSAPNSPCDIRLSPFPLLGLSFPTCKISRKNQM
LSRVFFYFAISWVFIFSYFVFSGSFPSEGTGST
RTCFSF*ILQAHSKTGLKLHEQHHSK*FFFSKAP
*QPIAMLSCSFLLTPFSPFSSPCSPTSVLRAVC
VCSLFLYTQYK*NKCV*C*TI
Frame 2
A*LTEVLAPGELVWTEEGA*TWRRRTTVRPMAFRRGPRPARPRNRPRRLPRNTRVPSAGSLCLMPR
SMSVRWRNMAGARCCLTWSVNTSTS*RRTTSA*
PSVMLTARRTGWTPPRRSRSRSGVAPGILPSQSS
STRLILPS*QKTSQDTTCACSCGQTSSRAGCHA
PLSRMPYWAPTLCRLSWVTMMLRSMWATMSASS
ASPLTRPGSWRRGSWSCIRHIGG*PREKQKSTS*
RMPRSFPCTE*TCTMPRTLRASTSC*AFVPMAC
SSTGTG*ESTALPGPRSSRSPTRGVTSISRSGL
GSMSNLRAQLALSSQTTGQPRDCGRSASSIIHSS
GWCPLSPHPRASW*WAPSSGTVGGPRHRLARPA
PSLTGLHPSLSVLPANGTPCPAALMEQSSPAQP
RSARTMMQGLTVTSGMRMASLGGNGQRLRRERSG
LQPRSRS*SS*TSQKMSC*STRPASMSSKGP*R
SPTANSSTGIETGNGSAGCPPPPPPPPPRAPLR
KPMREQG*GRAPRRKSNHHVPGPQRVTQAMRTRT
RRGTRCS*RTTTWPLSASAPASRSALRLAWRLR
WTSRSLVTTMAAPSKTSPAACLSSTGTKATRTL
RACCSPGISTRGPPARMMSLGALRTARIEGPAPP
RICPSLSP*KQKP*LSAVWPLERRLSRRPYCRP
ESPLWITPRRTVSSPGRGQLP*SQAHRRWPRKS
VLFLRSSGKMSSPAPTAPLRKPSQPPPPPMSPKL
*KEGFLRQGSRSESSLLGMKMSIKTRPWLWPSR
RPNCSILICW*PKLSYTEKQTHPQRRGTRSHRN
PDLCEEILAFLVQPKPENH*EGAFILDSPTQH*R
PSCDVLSLMRDWEGKSIYI*IYRDIDIYTGNTA
SLHCCWGWQSSWLTATTDI*TPTFPLQTN*RTG
GIFFKKKNYIITIIPCSPLSPAK*ETQARPR*L*
KSLPPWFCTLQLADEQFHLFFSSISKAHLNAKE
NTCTAKQEKSQQQDTHSQPFSEKKRKFPTWKER
GGTLDSYFLDLDTGLQNLPSSLPPPLTLNSQCLA
VIFCLGSLLPLPPSPTPHPSPSVSWSF*GPLQM
TLL*NEKKKRKQEQKTKPQEGK*TLYAYGFSL*
RCSL*EVCTDVL*SYVYYI*QEKILK*TVLVSMK
LTF*NYNYLTVIDVS*GS*ISLNWPS*GDLDSG
CGLAHSRG*RVQCSNTVCGVCNWLIGGEGWGAL
MERCGFGKKEATQMSSPKCQFKTPSPCPPGSNSQ
GLVCAQVLGPSLGLCC*SCHSRGPWLSPYLPTG
LALVFSLLSLSLFFFFLPHSALP*PHCNNQLHI
QREVVLSAIVEDGGFNLTV*KFPAKPFPLLSSLF
*IISSSQAKVAMVRRLHGADPERSKLHLQSPPL
SQDKAETDG*CCS*APALHKTLAWRPPSQSTAE
L*ACAQKLPQDHRNPSRSSHHKLGIALCHTWASS
GLSATSYFSELRKCPLMRENVPLHCEFLSSILP
PSPPSKPVNKFIPQVFTDYLLVPGTILRLKKVG
GEGGT*GAT*ASFIFQPWLAHLRASPHSRQPIGA
*PRDAPRRPRLDASLWLVSDDIHLSCLAGAGLR
QGRKSE*HLLLWANGKFSGAAESVAFPLVQAGG
STPTPPECSSTLSIHQVLSTILVEKPQNLLPALL
ESSPSFWVKSWSGGSILSGPLRSRNSSLQEPGV
LSTLNTPQREDPCCGFCTWLWGRGEVTRLSLWS
LWATRVWGNHHPADAVTSLLRRCRQCHEGGGDLQ
S*NLGHCFLPILLFVENRDVCLVCLQPTFPFLF
FVSHPLCATSPPRRPCSIVEKVPEGG*EFWVTI
LAQLLTHHVTSGYPHSPSWASVSRLAK*AERTRC
SPGSFSTLLSHGSSFSLILFSLDLFHLRVQEVP
GPVSVFESCKHIPRLA*NCMSNITRNNFFFQKH
LNNQLRCCPVPFYSHPSLLSRPHAPPPQCSVLYA
CALCSCILNISEINVFDAEP
Sequence NM_012156
AGTCGGCATCCATCAGCGGGCGGGGGTGTCGCCGAACAGGCTGCTCCGCAGAGCCCGCCGCGACCCCGCGCCGCCCCGCCCCGCGGCCTGCCTGCCAGAGGAGCCGAGGGGGCCGCCCCTCGCCCAACCTGCCCGACATGGGGAACCCCGGGCCCAGGCGTGCTGGTCACCATGACAACAGAGACAGGCCCCGACTCTGA
GGTGAAGAAAGCTCAGGAGGAGGCCCCGCAGCAGCCCGAGGCTGCTGCCGCTGTGACCACCCCTGTGACCCCTGCAGGCCACGGCCACCCAGAGGCCAAC
TCCAATGAGAAGCATCCATCCCAGCAGGACACGCGGCCTGCTGAACAGAGCCTAGACATGGAGGAGAAGGACTACAGTGAGGCCGATGGCCTTTCGGAGA
GGACCACGCCCAGCAAGGCCCAGAAATCGCCCCAGAAGATTGCCAAGAAATACAAGAGTGCCATCTGCCGGGTCACTCTGCTTGATGCCTCGGAGTATGA
GTGTGAGGTGGAGAAACATGGCCGGGGCCAGGTGCTGTTTGACCTGGTCTGTGAACACCTCAACCTCCTAGAGAAGGACTACTTCGGCCTGACCTTCTGT
GATGCTGACAGCCAGAAGAACTGGCTGGACCCCTCCAAGGAGATCAAGAAGCAGATCCGGAGTAGCCCCTGGAATTTTGCCTTCACAGTCAAGTTCTACC
CGCCTGATCCTGCCCAGCTGACAGAAGACATCACAAGATACTACCTGTGCCTGCAGCTGCGGGCAGACATCATCACGGGCCGGCTGCCATGCTCCTTTGT
CACGCATGCCCTACTGGGCTCCTACGCTGTGCAGGCTGAGCTGGGTGACTATGATGCTGAGGAGCATGTGGGCAACTATGTCAGCGAGCTCCGCTTCGCC
CCTAACCAGACCCGGGAGCTGGAGGAGAGGATCATGGAGCTGCATAAGACATATAGGGGGATGACCCCGGGAGAAGCAGAAATCCACTTCTTAGAGAATG
CCAAGAAGCTTTCCATGTACGGAGTAGACCTGCACCATGCCAAGGACTCTGAGGGCATCGACATCATGTTAGGCGTTTGTGCCAATGGCCTGCTCATCTA
CCGGGACCGGCTGAGAATCAACCGCTTTGCCTGGCCCAAGATCCTCAAGATCTCCTACAAGAGGAGTAACTTCTATATCAAGATCCGGCCTGGGGAGTAT
GAGCAATTTGAGAGCACAATTGGCTTTAAGCTCCCAAACCACCGGTCAGCCAAGAGACTGTGGAAGGTCTGCATCGAGCATCATACATTCTTCCGGCTGG
TGTCCCCTGAGCCCCCACCCAAGGGCTTCCTGGTGATGGGCTCCAAGTTCCGGTACAGTGGGAGGACCCAGGCACAGACTCGCCAGGCCAGCGCCCTCAT
TGACCGGCCTGCACCCTTCTTTGAGCGTTCTTCCAGCAAACGGTACACCATGTCCCGCAGCCTTGATGGAGCAGAGTTCTCCCGCCCAGCCTCGGTCAGC
GAGAACCATGATGCAGGGCCTGACGGTGACAAGCGGGATGAGGATGGCGAGTCTGGGGGGCAACGGTCAGAGGCTGAGGAGGGAGAGGTCAGGACTCCAA
CCAAGATCAAGGAGCTAAAGCCGGAGCAGGAAACCACGCCGAGACACAAGCAGGAGTTCTTAGACAAGCCAGAAGATGTCTTGCTGAAGCACCAGGCCAG
CATCAATGAGCTCAAAAGGACCCTGAAGGAGCCCAACAGCAAACTCATCCACCGGGATCGAGACTGGGAACGGGAGCGCAGGCTGCCCTCCTCCCCCGCC
TCCCCCTCCCCCAAGGGCACCCCTGAGAAAGCCAATGAGAGAGCAGGGCTGAGGGAGGGCTCCGAGGAGAAAGTCAAACCACCACGTCCCCGGGCCCCAG
AGAGTGACACAGGCGATGAGGACCAGGACCAGGAGAGGGACACGGTGTTCCTGAAGGACAACCACCTGGCCATTGAGCGCAAGTGCTCCAGCATCACGGT
CAGCTCTACGTCTAGCCTGGAGGCTGAGGTGGACTTCACGGTCATTGGTGACTACCATGGCAGCGCCTTCGAAGACTTCTCCCGCAGCCTGCCTGAGCTC
GACCGGGACAAAAGCGACTCGGACACTGAGGGCCTGCTGTTCTCCCGGGATCTCAACAAGGGGGCCCCCAGCCAGGATGATGAGTCTGGGGGCATTGAGG
ACAGCCCGGATCGAGGGGCCTGCTCCACCCCGGATATGCCCCAGTTTGAGCCCGTGAAAACAGAAACCATGACTGTCAGCAGTCTGGCCATTAGAAAGAA
GATTGAGCCGGAGGCCGTACTGCAGACCAGAGTCTCCGCTATGGATAACACCCAGCAGGTTGATGGGAGTGCCTCAGTGGGGAGGGAGTTCATAGCAACC
ACTCCCTCCATCACCACGGAGACCATATCGACCACCATGGAGAACAGTCTCAAGTCCGGGAAGGGGGCAGCTGCCATGATCCCAGGCCCACAGACGGTGG
CCACGGAAATCCGTTCTCTTTCTCCGATCATCGGGAAAGATGTCCTCACCAGCACCTACGGCGCCACTGCGGAAACCCTCTCAACCTCCACCACCACCCA
TGTCACCAAAACTGTGAAAGGAGGGTTTTCTGAGACAAGGATCGAGAAGCGAATCATCATTACTGGGGATGAAGATGTCGATCAAGACCAGGCCCTGGCT
TTGGCCATCAAGGAGGCCAAACTGCAGCATCCTGATATGCTGGTAACCAAAGCTGTCGTATACAGAGAAACAGACCCATCCCCAGAGGAGAGGGACAAGA
AGCCACAGGAATCCTGACCTCTGTGAAGAGATCCTGGCATTTCTGGTCCAACCCAAGCCAGAGAACCATTAAGAAGGGGCCTTCATTCTGGATTCTCCGA
CGCAACACTGACGTCCCAGCTGCGACGTACTGTCACTGATGAGAGACTGGGAAGGGAAAAGCATATATATATAGATATATAGAGATATAGATATATATAC
AGGAAACACCGCATCCTTGCACTGCTGCTGGGGCTGGCAGAGCAGTTGGCTGACAGCAACAACCGACATCTGAACACCTACATTTCCTTTGCAGACAAAT
TGAAGAACTGGTGGGATTTTTTTCAAGAAAAAAAATTATATAATAACTATAATCCCTTGCTCACCCCTTTCCCCCGCCAAATAAGAAACGCAAGCCAGAC
CACGATGATTGTAGAAGTCCCTCCCGCCCTGGTTCTGCACGTTACAGTTAGCAGACGAGCAATTCCATTTGTTCTTCTCCAGCATCTCTAAGGCCCACTT
GAATGCAAAGGAAAACACTTGCACAGCAAAGCAAGAGAAGTCACAGCAGCAAGACACGCACAGTCAACCATTTTCCGAGAAAAAAAGAAAATTCCCCACT
TGGAAAGAAAGAGGAGGAACACTGGATTCTTACTTTCTGGATCTTGACACTGGGCTGCAAAACCTACCTTCCTCTCTCCCGCCTCCCCTCACCCTCAACT
CTCAATGTCTTGCTGTCATTTTCTGTCTCGGCTCCCTCCTCCCCCTTCCCCCTTCCCCCACCCCACACCCTTCACCCTCTGTGTCCTGGTCCTTCTGAGG
GCCACTGCAGATGACTCTCCTTTGAAATGAGAAAAAGAAAAGAAAGCAAGAACAGAAAACGAAGCCACAGGAAGGGAAGTAGACATTGTATGCTTATGGT
TTCTCATTATGAAGGTGCAGCTTGTAGGAGGTTTGTACGGATGTGCTTTGAAGTTATGTATATTACATATAACAGGAAAAAATATTAAAATAAACAGTGC
TGGTAAGTATGAAGCTGACATTCTAAAATTATAATTATCTGACTGTGATTGATGTATCCTGAGGTTCCTAGATCTCACTGAACTGGCCCAGCTAAGGAGA
CCTGGACTCTGGGTGTGGGTTGGCTCACAGTAGGGGCTGACGGGTTCAGTGTAGTAATACTGTGTGTGGTGTTTGTAATTGGTTGATTGGTGGGGAGGGG
TGGGGGGCCCTAATGGAGAGGTGTGGGTTTGGCAAGAAAGAAGCAACACAGATGTCGTCCCCAAAATGCCAGTTCAAGACACCTTCTCCCTGCCCCCCTG
GTAGTAACAGTCAGGGCCTGGTCTGTGCTCAGGTACTGGGTCCCAGTCTGGGACTCTGCTGCTGAAGTTGCCACAGTAGAGGTCCCTGGCTTAGTCCTTA
TCTCCCTACGGGGCTTGCCTTGGTTTTCAGTCTTCTCTCTCTTTCTCTCTTTTTTTTTTTTTTGCCACATTCTGCCCTTCCCTGACCCCATTGTAATAAC
CAACTCCATATCCAAAGGGAGGTGGTGCTCTCAGCCATTGTAGAAGATGGTGGCTTTAACCTGACTGTCTAAAAATTCCCAGCTAAGCCTTTTCCTCTAC
TCTCTTCCTTGTTCTGAATCATTTCTTCTTCTCAGGCCAAAGTAGCCATGGTAAGGAGGCTTCATGGGGCAGACCCTGAAAGATCAAAACTGCATTTGCA
AAGCCCTCCCCTGTCCCAGGACAAAGCTGAGACTGACGGGTGATGTTGCTCATAGGCTCCAGCTCTGCATAAGACCTTGGCTTGGAGACCTCCCTCTCAG
TCAACAGCTGAACTCTGAGCTTGTGCCCAGAAATTACCCCAAGACCACAGGAACCCTTCAAGAAGCTCCCATCACAAGCTTGGCATTGCTCTCTGCCACA
CGTGGGCTTCCTCAGGCTTGTCTGCCACAAGCTACTTCTCTGAGCTCAGAAAGTGCCCCTTGATGAGGGAAAATGTCCCACTGCACTGCGAATTTCTCAG
TTCCATTTTACCTCCCAGTCCTCCTTCTAAACCAGTTAATAAATTCATTCCACAAGTATTTACTGATTACCTGCTTGTGCCAGGGACTATTCTCAGGCTG
AAGAAGGTGGGAGGGGAGGGCGGAACCTGAGGAGCCACCTGAGCCAGCTTTATATTTCAACCATGGCTGGCCCATCTGAGAGCATCTCCCCACTCTCGCC
AACCTATCGGGGCATAGCCCAGGGATGCCCCCAGGCGGCCCAGGTTAGATGCGTCCCTTTGGCTTGTCAGTGATGACATACACCTTAGCTGCTTAGCTGG
TGCTGGCCTGAGGCAGGGCAGGAAATCAGAATAGCATTTGCTTCTCTGGGCAAATGGGAAGTTCAGCGGGGCAGCAGAATCAGTGGCATTCCCCCTGGTG
CAGGCCGGTGGGTCCACTCCAACTCCCCCTGAGTGTAGCAGCACACTTTCCATACACCAGGTTCTTTCTACAATCCTGGTGGAAAAGCCACAGAACCTTC
TTCCTGCCCTTCTTGAGAGTTCCCCCTCTTTCTGGGTCAAGAGCTGGAGTGGTGGCTCCATCCTCTCTGGGCCACTTCGGTCTAGGAACTCATCTTTGCA
GGAACCAGGAGTCCTGAGCACACTGAACACACCTCAGAGGGAGGATCCTTGTTGTGGATTTTGCACCTGGCTTTGGGGCAGGGGTGAAGTGACCAGGCTT
AGCTTGTGGAGTTTATGGGCCACCAGGGTTTGGGGAAATCACCATCCCGCGGATGCTGTGACCTCCCTTCTACGGAGATGCAGGCAGTGCCACGAGGGAG
GAGGGGACCTGCAAAGCTAGAATCTAGGGCACTGTTTCCTCCCCATCCTTCTCTTTGTAGAGAATAGAGACGTTTGTCTTGTCTGTCTTCAACCTACTTT
TCCTTTTCTCTTTTTTGTTTCTCATCCTCTCTGTGCCACCTCTCCACCCAGGAGGCCATGTAGCATAGTGGAAAAAGTCCCTGAGGGCGGTTAGGAGTTC
TGGGTGACCATCCTGGCTCAGCTCCTAACTCACCATGTGACATCAGGCTATCCCCATTCCCCCTCTTGGGCCTCAGTTTCCCGACTTGCAAAATAAGCAG
AAAGAACCAGATGCTCTCCAGGGTCTTTTTCTACTTTGCTATCTCATGGGTCTTCATTTTCTCTTATTTTGTTTTCTCTGGATCTTTTCCATCTGAGGGT
ACAGGAAGTACCAGGACCTGTTTCAGTTTTTGAATCCTGCAAGCACATTCCAAGACTGGCCTGAAACTGCATGAGCAACATCACTCGAAATAATTTTTTT
TTTCAAAAGCACCTTAACAACCAATTGCGATGCTGTCCTGTTCCTTTTTACTCACACCCTTCTCTCCTTTCTCGTCCCCATGCTCCCCCACCTCAGTGCT
CCGTGCTGTATGCGTGTGCTCTCTGTTCTTGTATACTCAATATAAGTGAAATAAATGTGTTTGATGCTGAACCATA
- refseq_EPB41L1.F3 (forward primer)
- refseq_EPB41L1.R3 (reverse primer)
- Single exon skipping
Frame 0
SRHPSAGGGVAEQAAPQSPPRPRAAPPRGLPARGAEGAAPRPTCPTWGTPGPGVLVTMTTETGPDSE
VKKAQEEAPQQPEAAAAVTTPVTPAGHGHPEAN
SNEKHPSQQDTRPAEQSLDMEEKDYSEADGLSE
RTTPSKAQKSPQKIAKKYKSAICRVTLLDASEYE
CEVEKHGRGQVLFDLVCEHLNLLEKDYFGLTFC
DADSQKNWLDPSKEIKKQIRSSPWNFAFTVKFY
PPDPAQLTEDITRYYLCLQLRADIITGRLPCSFV
THALLGSYAVQAELGDYDAEEHVGNYVSELRFA
PNQTRELEERIMELHKTYRGMTPGEAEIHFLEN
AKKLSMYGVDLHHAKDSEGIDIMLGVCANGLLIY
RDRLRINRFAWPKILKISYKRSNFYIKIRPGEY
EQFESTIGFKLPNHRSAKRLWKVCIEHHTFFRL
VSPEPPPKGFLVMGSKFRYSGRTQAQTRQASALI
DRPAPFFERSSSKRYTMSRSLDGAEFSRPASVS
ENHDAGPDGDKRDEDGESGGQRSEAEEGEVRTP
TKIKELKPEQETTPRHKQEFLDKPEDVLLKHQAS
INELKRTLKEPNSKLIHRDRDWERERRLPSSPA
SPSPKGTPEKANERAGLREGSEEKVKPPRPRAP
ESDTGDEDQDQERDTVFLKDNHLAIERKCSSITV
SSTSSLEAEVDFTVIGDYHGSAFEDFSRSLPEL
DRDKSDSDTEGLLFSRDLNKGAPSQDDESGGIE
DSPDRGACSTPDMPQFEPVKTETMTVSSLAIRKK
IEPEAVLQTRVSAMDNTQQVDGSASVGREFIAT
TPSITTETISTTMENSLKSGKGAAAMIPGPQTV
ATEIRSLSPIIGKDVLTSTYGATAETLSTSTTTH
VTKTVKGGFSETRIEKRIIITGDEDVDQDQALA
LAIKEAKLQHPDMLVTKAVVYRETDPSPEERDK
KPQES*PL*RDPGISGPTQAREPLRRGLHSGFSD
ATLTSQLRRTVTDERLGREKHIYIDI*RYRYIY
RKHRILALLLGLAEQLADSNNRHLNTYISFADK
LKNWWDFFQEKKLYNNYNPLLTPFPRQIRNASQT
TMIVEVPPALVLHVTVSRRAIPFVLLQHL*GPL
ECKGKHLHSKAREVTAARHAQSTIFREKKKIPH
LERKRRNTGFLLSGS*HWAAKPTFLSPASPHPQL
SMSCCHFLSRLPPPPSPFPHPTPFTLCVLVLLR
ATADDSPLK*EKEKKARTENEATGREVDIVCLW
FLIMKVQLVGGLYGCALKLCILHITGKNIKINSA
GKYEADILKL*LSDCD*CILRFLDLTELAQLRR
PGLWVWVGSQ*GLTGSV**YCVWCL*LVDWWGG
VGGPNGEVWVWQERSNTDVVPKMPVQDTFSLPPW
**QSGPGLCSGTGSQSGTLLLKLPQ*RSLA*SL
SPYGACLGFQSSLSFSLFFFFATFCPSLTPL**
PTPYPKGGGALSHCRRWWL*PDCLKIPS*AFSST
LFLVLNHFFFSGQSSHGKEASWGRP*KIKTAFA
KPSPVPGQS*D*RVMLLIGSSSA*DLGLETSLS
VNS*TLSLCPEITPRPQEPFKKLPSQAWHCSLPH
VGFLRLVCHKLLL*AQKVPLDEGKCPTALRISQ
FHFTSQSSF*TS**IHSTSIY*LPACARDYSQA
EEGGRGGRNLRSHLSQLYISTMAGPSESISPLSP
TYRGIAQGCPQAAQVRCVPLACQ**HTP*LLSW
CWPEAGQEIRIAFASLGKWEVQRGSRISGIPPG
AGRWVHSNSP*V*QHTFHTPGSFYNPGGKATEPS
SCPS*EFPLFLGQELEWWLHPLWATSV*ELIFA
GTRSPEHTEHTSEGGSLLWILHLALGQG*SDQA
*LVEFMGHQGLGKSPSRGCCDLPSTEMQAVPRGR
RGPAKLESRALFPPHPSLCRE*RRLSCLSSTYF
SFSLFCFSSSLCHLSTQEAM*HSGKSP*GRLGV
LGDHPGSAPNSPCDIRLSPFPLLGLSFPTCKISR
KNQMLSRVFFYFAISWVFIFSYFVFSGSFPSEG
TGSTRTCFSF*ILQAHSKTGLKLHEQHHSK*FF
FSKAP*QPIAMLSCSFLLTPFSPFSSPCSPTSVL
RAVCVCSLFLYTQYK*NKCV*C*TI
Frame 1
VGIHQRAGVSPNRLLRRARRDPAPPRPAACLPEEPRGPPLAQPARHGEPRAQACWSP*QQRQAPTL
R*RKLRRRPRSSPRLLPL*PPL*PLQATATQRPT
PMRSIHPSRTRGLLNRA*TWRRRTTVRPMAFRR
GPRPARPRNRPRRLPRNTRVPSAGSLCLMPRSM
SVRWRNMAGARCCLTWSVNTSTS*RRTTSA*PSV
MLTARRTGWTPPRRSRSRSGVAPGILPSQSSST
RLILPS*QKTSQDTTCACSCGQTSSRAGCHAPL
SRMPYWAPTLCRLSWVTMMLRSMWATMSASSASP
LTRPGSWRRGSWSCIRHIGG*PREKQKSTS*RM
PRSFPCTE*TCTMPRTLRASTSC*AFVPMACSS
TGTG*ESTALPGPRSSRSPTRGVTSISRSGLGSM
SNLRAQLALSSQTTGQPRDCGRSASSIIHSSGW
CPLSPHPRASW*WAPSSGTVGGPRHRLARPAPS
LTGLHPSLSVLPANGTPCPAALMEQSSPAQPRSA
RTMMQGLTVTSGMRMASLGGNGQRLRRERSGLQ
PRSRS*SRSRKPRRDTSRSS*TSQKMSC*STRP
ASMSSKGP*RSPTANSSTGIETGNGSAGCPPPPP
PPPPRAPLRKPMREQG*GRAPRRKSNHHVPGPQ
RVTQAMRTRTRRGTRCS*RTTTWPLSASAPASR
SALRLAWRLRWTSRSLVTTMAAPSKTSPAACLSS
TGTKATRTLRACCSPGISTRGPPARMMSLGALR
TARIEGPAPPRICPSLSP*KQKP*LSAVWPLER
RLSRRPYCRPESPLWITPSRLMGVPQWGGSS*QP
LPPSPRRPYRPPWRTVSSPGRGQLP*SQAHRRW
PRKSVLFLRSSGKMSSPAPTAPLRKPSQPPPPP
MSPKL*KEGFLRQGSRSESSLLGMKMSIKTRPWL
WPSRRPNCSILICW*PKLSYTEKQTHPQRRGTR
SHRNPDLCEEILAFLVQPKPENH*EGAFILDSP
TQH*RPSCDVLSLMRDWEGKSIYI*IYRDIDIYT
GNTASLHCCWGWQSSWLTATTDI*TPTFPLQTN
*RTGGIFFKKKNYIITIIPCSPLSPAK*ETQAR
PR*L*KSLPPWFCTLQLADEQFHLFFSSISKAHL
NAKENTCTAKQEKSQQQDTHSQPFSEKKRKFPT
WKERGGTLDSYFLDLDTGLQNLPSSLPPPLTLN
SQCLAVIFCLGSLLPLPPSPTPHPSPSVSWSF*G
PLQMTLL*NEKKKRKQEQKTKPQEGK*TLYAYG
FSL*RCSL*EVCTDVL*SYVYYI*QEKILK*TV
LVSMKLTF*NYNYLTVIDVS*GS*ISLNWPS*GD
LDSGCGLAHSRG*RVQCSNTVCGVCNWLIGGEG
WGALMERCGFGKKEATQMSSPKCQFKTPSPCPP
GSNSQGLVCAQVLGPSLGLCC*SCHSRGPWLSPY
LPTGLALVFSLLSLSLFFFFLPHSALP*PHCNN
QLHIQREVVLSAIVEDGGFNLTV*KFPAKPFPL
LSSLF*IISSSQAKVAMVRRLHGADPERSKLHLQ
SPPLSQDKAETDG*CCS*APALHKTLAWRPPSQ
STAEL*ACAQKLPQDHRNPSRSSHHKLGIALCH
TWASSGLSATSYFSELRKCPLMRENVPLHCEFLS
SILPPSPPSKPVNKFIPQVFTDYLLVPGTILRL
KKVGGEGGT*GAT*ASFIFQPWLAHLRASPHSR
QPIGA*PRDAPRRPRLDASLWLVSDDIHLSCLAG
AGLRQGRKSE*HLLLWANGKFSGAAESVAFPLV
QAGGSTPTPPECSSTLSIHQVLSTILVEKPQNL
LPALLESSPSFWVKSWSGGSILSGPLRSRNSSLQ
EPGVLSTLNTPQREDPCCGFCTWLWGRGEVTRL
SLWSLWATRVWGNHHPADAVTSLLRRCRQCHEG
GGDLQS*NLGHCFLPILLFVENRDVCLVCLQPTF
PFLFFVSHPLCATSPPRRPCSIVEKVPEGG*EF
WVTILAQLLTHHVTSGYPHSPSWASVSRLAK*A
ERTRCSPGSFSTLLSHGSSFSLILFSLDLFHLRV
QEVPGPVSVFESCKHIPRLA*NCMSNITRNNFF
FQKHLNNQLRCCPVPFYSHPSLLSRPHAPPPQC
SVLYACALCSCILNISEINVFDAEP
Frame 2
SASISGRGCRRTGCSAEPAATPRRPAPRPACQRSRGGRPSPNLPDMGNPGPRRAGHHDNRDRPRL*
GEESSGGGPAAARGCCRCDHPCDPCRPRPPRGQ
LQ*EASIPAGHAAC*TEPRHGGEGLQ*GRWPFGE
DHAQQGPEIAPEDCQEIQECHLPGHSA*CLGV*
V*GGETWPGPGAV*PGL*TPQPPREGLLRPDLL
*C*QPEELAGPLQGDQEADPE*PLEFCLHSQVLP
A*SCPADRRHHKILPVPAAAGRHHHGPAAMLLC
HACPTGLLRCAG*AG*L*C*GACGQLCQRAPLR
P*PDPGAGGEDHGAA*DI*GDDPGRSRNPLLREC
QEAFHVRSRPAPCQGL*GHRHHVRRLCQWPAHL
PGPAENQPLCLAQDPQDLLQEE*LLYQDPAWGV
*AI*EHNWL*APKPPVSQETVEGLHRASYILPAG
VP*APTQGLPGDGLQVPVQWEDPGTDSPGQRPH
*PACTLL*AFFQQTVHHVPQP*WSRVLPPSLGQ
REP*CRA*R*QAG*GWRVWGATVRG*GGRGQDSN
QDQGAKAGAGNHAETQAGVLRQARRCLAEAPGQ
HQ*AQKDPEGAQQQTHPPGSRLGTGAQAALLPR
LPLPQGHP*ESQ*ESRAEGGLRGESQTTTSPGPR
E*HRR*GPGPGEGHGVPEGQPPGH*AQVLQHHG
QLYV*PGG*GGLHGHW*LPWQRLRRLLPQPA*A
RPGQKRLGH*GPAVLPGSQQGGPQPG**VWGH*G
QPGSRGLLHPGYAPV*ARENRNHDCQQSGH*KE
D*AGGRTADQSLRYG*HPAG*WECLSGEGVHSN
HSLHHHGDHIDHHGEQSQVREGGSCHDPRPTDGG
HGNPFSFSDHRERCPHQHLRRHCGNPLNLHHHP
CHQNCERRVF*DKDREANHHYWG*RCRSRPGPG
FGHQGGQTAAS*YAGNQSCRIQRNRPIPRGEGQE
ATGILTSVKRSWHFWSNPSQRTIKKGPSFWILR
RNTDVPAATYCH**ETGKGKAYIYRYIEI*IYI
QETPHPCTAAGAGRAVG*QQQPTSEHLHFLCRQI
EELVGFFSRKKII**L*SLAHPFPPPNKKRKPD
HDDCRSPSRPGSARYS*QTSNSICSSPASLRPT
*MQRKTLAQQSKRSHSSKTRTVNHFPRKKENSPL
GKKEEEHWILTFWILTLGCKTYLPLSRLPSPST
LNVLLSFSVSAPSSPFPLPPPHTLHPLCPGPSE
GHCR*LSFEMRKRKESKNRKRSHRKGSRHCMLMV
SHYEGAACRRFVRMCFEVMYITYNRKKY*NKQC
W*V*S*HSKIIII*L*LMYPEVPRSH*TGPAKE
TWTLGVGWLTVGADGFSVVILCVVFVIG*LVGRG
GGP*WRGVGLARKKQHRCRPQNASSRHLLPAPL
VVTVRAWSVLRYWVPVWDSAAEVATVEVPGLVL
ISLRGLPWFSVFSLFLSFFFFCHILPFPDPIVIT
NSISKGRWCSQPL*KMVALT*LSKNSQLSLFLY
SLPCSESFLLLRPK*PW*GGFMGQTLKDQNCIC
KALPCPRTKLRLTGDVAHRLQLCIRPWLGDLPLS
QQLNSELVPRNYPKTTGTLQEAPITSLALLSAT
RGLPQACLPQATSLSSESAP**GKMSHCTANFS
VPFYLPVLLLNQLINSFHKYLLITCLCQGLFSG*
RRWEGRAEPEEPPEPALYFNHGWPI*EHLPTLA
NLSGHSPGMPPGGPG*MRPFGLSVMTYTLAA*L
VLA*GRAGNQNSICFSGQMGSSAGQQNQWHSPWC
RPVGPLQLPLSVAAHFPYTRFFLQSWWKSHRTF
FLPFLRVPPLSGSRAGVVAPSSLGHFGLGTHLC
RNQES*AH*THLRGRILVVDFAPGFGAGVK*PGL
ACGVYGPPGFGEITIPRML*PPFYGDAGSATRE
EGTCKARI*GTVSSPSFSL*RIETFVLSVFNLL
FLFSFLFLILSVPPLHPGGHVA*WKKSLRAVRSS
G*PSWLSS*LTM*HQAIPIPPLGPQFPDLQNKQ
KEPDALQGLFLLCYLMGLHFLLFCFLWIFSI*G
YRKYQDLFQFLNPASTFQDWPETA*ATSLEIIFF
FKSTLTTNCDAVLFLFTHTLLSFLVPMLPHLSA
PCCMRVLSVLVYSI*VK*MCLMLNH
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