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Sequences

Sequence NM_001112

GCGGCGGCGGCGGCGGCGGCGGCAGCGGCGGCCAAGCGGCCAGGTTGGCGGCCGGGGCTCCGGGCCGCGCGAGGCCACGGCCACGCCGCGCCGCTGCGCA CAACCAACGAGGCAGAGCGCCGCCCGGCGCGAGACTGCGGCCGAAGCGTGGGGCGCGCGTGCGGAGGACCAGGCGCGGCGCGGCTGCGGCTGAGAGTGGA GCCTTTCAGGCTGGCATGGAGAGCTTAAGGGGCAACTGAAGGAGACACACTGGCCAAGCGCGGAGTTCTGCTTACTTCAGTCCTGCTGAGATACTCTCTC AGTCCGCTCGCACCGAAGGAAGCTGCCTTGGGATCAGAGCAGACATAAAGCTAGAAAAATTTCAAGACAGAAACAGTCTCCGCCAGTCAAGAAACCCTCA AAAGTATTTTGCCATGGATATAGAAGATGAAGAAAACATGAGTTCCAGCAGCACTGATGTGAAGGAAAACCGCAATCTGGACAACGTGTCCCCCAAGGAT GGCAGCACACCTGGGCCTGGCGAGGGCTCTCAGCTCTCCAATGGGGGTGGTGGTGGCCCCGGCAGAAAGCGGCCCCTGGAGGAGGGCAGCAATGGCCACT CCAAGTACCGCCTGAAGAAAAGGAGGAAAACACCAGGGCCCGTCCTCCCCAAGAACGCCCTGATGCAGCTGAATGAGATCAAGCCTGGTTTGCAGTACAC ACTCCTGTCCCAGACTGGGCCCGTGCACGCGCCTTTGTTTGTCATGTCTGTGGAGGTGAATGGCCAGGTTTTTGAGGGCTCTGGTCCCACAAAGAAAAAG GCAAAACTCCATGCTGCTGAGAAGGCCTTGAGGTCTTTCGTTCAGTTTCCTAATGCCTCTGAGGCCCACCTGGCCATGGGGAGGACCCTGTCTGTCAACA CGGACTTCACATCTGACCAGGCCGACTTCCCTGACACGCTCTTCAATGGTTTTGAAACTCCTGACAAGGCGGAGCCTCCCTTTTACGTGGGCTCCAATGG GGATGACTCCTTCAGTTCCAGCGGGGACCTCAGCTTGTCTGCTTCCCCGGTGCCTGCCAGCCTAGCCCAGCCTCCTCTCCCTGTCTTACCACCATTCCCA CCCCCGAGTGGGAAGAATCCCGTGATGATCTTGAACGAACTGCGCCCAGGACTCAAGTATGACTTCCTCTCCGAGAGCGGGGAGAGCCATGCCAAGAGCT TCGTCATGTCTGTGGTCGTGGATGGTCAGTTCTTTGAAGGCTCGGGGAGAAACAAGAAGCTTGCCAAGGCCCGGGCTGCGCAGTCTGCCCTGGCCGCCAT TTTTAACTTGCACTTGGATCAGACGCCATCTCGCCAGCCTATTCCCAGTGAGGGTCTTCAGCTGCATTTACCGCAGGTTTTAGCTGACGCTGTCTCACGC CTGGTCCTGGGTAAGTTTGGTGACCTGACCGACAACTTCTCCTCCCCTCACGCTCGCAGAAAAGTGCTGGCTGGAGTCGTCATGACAACAGGCACAGATG TTAAAGATGCCAAGGTGATAAGTGTTTCTACAGGAACAAAATGTATTAATGGTGAATACATGAGTGATCGTGGCCTTGCATTAAATGACTGCCATGCAGA AATAATATCTCGGAGATCCTTGCTCAGATTTCTTTATACACAACTTGAGCTTTACTTAAATAACAAAGATGATCAAAAAAGATCCATCTTTCAGAAATCA GAGCGAGGGGGGTTTAGGCTGAAGGAGAATGTCCAGTTTCATCTGTACATCAGCACCTCTCCCTGTGGAGATGCCAGAATCTTCTCACCACATGAGCCAA TCCTGGAAGAACCAGCAGATAGACACCCAAATCGTAAAGCAAGAGGACAGCTACGGACCAAAATAGAGTCTGGTGAGGGGACGATTCCAGTGCGCTCCAA TGCGAGCATCCAAACGTGGGACGGGGTGCTGCAAGGGGAGCGGCTGCTCACCATGTCCTGCAGTGACAAGATTGCACGCTGGAACGTGGTGGGCATCCAG GGATCCCTGCTCAGCATTTTCGTGGAGCCCATTTACTTCTCGAGCATCATCCTGGGCAGCCTTTACCACGGGGACCACCTTTCCAGGGCCATGTACCAGC GGATCTCCAACATAGAGGACCTGCCACCTCTCTACACCCTCAACAAGCCTTTGCTCAGTGGCATCAGCAATGCAGAAGCACGGCAGCCAGGGAAGGCCCC CAACTTCAGTGTCAACTGGACGGTAGGCGACTCCGCTATTGAGGTCATCAACGCCACGACTGGGAAGGATGAGCTGGGCCGCGCGTCCCGCCTGTGTAAG CACGCGTTGTACTGTCGCTGGATGCGTGTGCACGGCAAGGTTCCCTCCCACTTACTACGCTCCAAGATTACCAAGCCCAACGTGTACCATGAGTCCAAGC TGGCGGCAAAGGAGTACCAGGCCGCCAAGGCGCGTCTGTTCACAGCCTTCATCAAGGCGGGGCTGGGGGCCTGGGTGGAGAAGCCCACCGAGCAGGACCA GTTCTCACTCACGCCCTGACCCGGGCAGACATGATGGGGGGTGCAGGGGGCTGTGGGCATCCAGCGTCATCCTCCAGAACCTCACATCTGAACTGGGGGC AGGTGCATACCTTGGGGAGGGAGTAGGGGGACACGGGGGACCACCAGGTGTCCACGGTTGTCCCCAGCATCTCACATCAGACCTGGGGCAGGTGCGCAGT GTGGGGAGGGGATGGGGTGCGTCAGGGCCCAGCATCGCCGCCTGGCATCTCTCTGCCGCAGCATTTCCCCTTCTGAACCGTCCAGTGACTGCTTTCAATC TCGGTTTACGTTTAGAAATTGAGTTCTACTGAGTAGGGCTTCCTTAAGTTTAGGAAAATAGAAATTACTTTGTGTGAAATTCTTGAATAAATAATTTATT CAGAGCTAGGAATGTGGTTTATAAAATAGGAAGTAATTGTGTCAGGTCACTTTTATGCCACATTATTTTAATTGCAAAAAAGCATCTATATATGGAGGAG GGTGGGAAAATAGAGGTAGGAAATAGTAGCCTAAAGGAAATCGCCACACGTCTGTCTAAACTTAGGTCTCTTTTCTCCGTAGGTACCTCCCTGGGTAGTT CCACACACTAGGTTGTAACAGTCTCTCCCTGAGGAGCAGACTCCCAGCATGGTGTAGCGTGGCCCTGTCATGCACATGGGGTCCCGCAGCAGTGACTGTG TGTCCTGCAGAGGCGTGACCCAGGCCCCTGTAGCCCTCAGCCTCCTCTAGAAGCTTCTGTACTCCTTGTAGGATCAGATCATGGAAAACTTTTCTCAGTT TACTTCTAAGTAATCACAGATAATACATGGCCAGTAATCCCAGGCTGGCCATTCATTCAGGTTTTTTAAAGGATATTTAACTTTTATGGACTAGAAGGAA TCACGAGGGCTACTGCACAATACATGGCCTAAGTTCCCTCTGTTCCTTCCTCTGAATCGAATGGATGTGGGTGACCGCCCGAAGGCCTTCACAGGATGGA AGTAGAATGATTTCAGTAGATACTCATTCTTGGAAAATGCCATAGTTTTAAATTATTGTTTCCAGCTTTATCAAAGACATGTTTGAAAAATAAAAAGCAT CCAAGTGAGAGCTGGTGAGACCACGTGCTGCTGGCGTAGTGTAGGCCAGACATTGACAGTCCTGACGGGAGCTCAGGGCTGCCCAGCGCCCAGCGTGCAC GGGACGGCCCCACGACAGAGGGAGTCAGCCCGGGAGGTCAGGAGCGCGGCGGGCGAGGGCCCTGTGTGGACCACCTCCACCAAGCTCAGAGATTTGCACC AGGTGCCTTGTTGCCTCCGCTCAGGATGAAAGAGGAGCTGAGAGAAGTGCTCTGCCTGCCAGTGCAGTGCCCAGCTCCAAGGCTCTAGAGGGTGTTCAGG TGGGTCTCCTGGGGCCATGGGGAGAGATTGGTGCAGACCTTACCCCACAGCATACACCTGCCACAGCGAAATCCAGGGTGTTGGCACCTGTGTGTCCGTG ATGAGCCTAGGAAACCAGAGCAGGGGCAGAGGGGCGTCATCCTCCCACCGGACGCTGGGAGCTCAGACCCCAAAACTGAAACACCGTGGCTTCGGCGGGG GGTGTGCCTCCTGATGTCAGGAGCCCCATCCACGTGTGTCCACACAGATCTCGTCGCAGCACGGCAGGAAGGGGTGCTGCTTAGGGCTCATTGTTGGGGA CATGACCGGGTTCAGCGGCTAGAACATCTGCCCCACAGCAGCCTCCTCCTCCACCGAAGAGGGTAGTTGTCTCCCTGAAGCAGTCACAGCAGGCGTCTCT GCCGCTCCGTCACCACAGTGGGGTTTTGTTCAGGCAGATCGCGCTGGGGTTCTGCACCTGCAGAAGGAGAGGGGTCTGTTGTCGCTGGCTTTCCCCCAAG CAGGCTCTTGCACACTCTAGAAAAAACACCTTGTAAGTCTGTGCATTTTTATTGTCTTGATAAATTGTATTTTTTTCTAATGGGGATTGGGAGATGGACT TCGTTTTTAAAAATATGTGGATTTTGGTTACCAAGTTTAGTGTTAATATATTCCATATACATACAAAACTACCCGGTATGTCTGGCTTTTCCCTTCTGTC AGGTAATAGCTAAAGTCAGCATGATTGCTCCCTGTACCACCCCAAATAAGTGAGTGCCTCACCTTGTGGGGCCTGAGCAGCTACCTTGAGACCATGTGAG GTGGCACCTTTCCGGGGTGGACTCGTGCGGCCTTGAGGACAGGCACAGGGCACCCTATCCCAAGCCGTCCAGGCAGGAGGAAGGCAGCCAAGGCAACTGG GTTCTGGGAGCCCTGGGTGGGGCAGCTGTGGGGAGGAACTGGGTTCGGGGAGCCCTGGGCGGGGCGGCTGTTGGGGGGAACTGGGTTCGGGGTGCCCTGG GCAGGGGGCTACTGGGGGGCGGCTGTGAGGAGGAGTTGGGTTCAGGGAGCCCTGGGCGGGGTGGCTGTCAGGGGGAACTGGGTTCCGGGAGCCCTGGGCC GGGGCAGGGGGCGGCTGTAGGAAGGAACTGGTTTCGGGGAGCCCTGGGCGGGGCGGCTGTGGGGAGGAAGGTGACGTGCAGGGGACCAGAGGCTCTGCAC TGCTCCTAGGACAGCTCATCTGTAATCAGAAAAAAAATAAACAAAATACAGAACGCTGACTCCTCCGTGAGACAGATCGGGGACCTTAGCACTTTAATCC CTCCCTTCTGAGCGCTCGGTGTGCACTTTTAGACTATAGCTGTTTCATTGACGTGTCACTCTCCATCCAGTGTCCTTGATGTGGCTTTTAGAGACTTAGC AGAAAATTCGACACAAGCAGGAACTTGATTTTTTAAGAAAAAATATTACATTTTGAGGACATTTTGACAAGTAGGGGAAGAGAGGGCTTCTGTTGTTTTG TTTTGTTTTGTTTTGTTAACTAAACCTGAAGTATTAATTCCACAAAGACACTGTCCCTCAGGACCACTCAGGTACAGCTCTGCCAGGGACAGAGTCCTGC TAGTGGGAGGTCTCAGGTGGGGCGGTGTGTTCTGTGCCATGAGGCAGCGACAGGTCCAGATGGATGTCGTCACCACCTTCCTCAGCTCTCATCACCTGGT CGTACGCCAGGCCCACCTCTTCCCAGCAAGGGACGCCAAAGAACTGCAGTTTTTATTCTGAGTCTTAATTTAACTTTTCATCATCTTTTCCTATTTTGGA GAATTTTTTGTAATTAAAAGCAATTATTTTAAAATGTGCAAGCCAGTATCTCACAAGGCATGGATTTCTGTGGAATTTATTTTTATTCAAATAACCATAT TTATCTCCAGGCTGTGGAATCGCCACTTTCTTTGTGAAGACAGTGTCTCTCCTTGTAATCTCACACAGGTACACTGAGGAGGGGACGGCTCCGTCTTCAC ATTGTGCACAGATCTGAGGATGGGATTAGCGAAGCTGTGGAGACTGCACATCCGGACCTGCCCATGTCTCAAAACAAACACATGTACAGTGGCTCTTTTT CCTTCTCAAACACTTTACCCCAGAAGCAGGTGGTCTGCCCCAGGCATAAAGAAGGAAAATTGGCCATCTTTCCCACCTCTAAATTCTGTAAAATTATAGA CTTGCTCAAAAGATTCCTTTTTATCATCCCCACGCTGTGTAAGTGGAAAGGGCATTGTGTTCCGTGTGTGTCCAGTTTACAGCGTCTCTGCCCCCTAGCG TGTTTTGTGACAATCTCCCTGGGTGAGGAGTGGGTGCACCCAGCCCCGAGGCCAGTGGTTGCTCGGGGCCTTCCGTGTGAGTTCTAGTGTTCACTTGATG CCGGGGAATAGAATTAGAGAAAACTCTGACCTGCCGGGTTCCAGGGACTGGTGGAGGTGGATGGCAGGTCCGACTCGACCATGACTTAGTTGTAAGGGTG TGTCGGCTTTTTCAGTCTCATGTGAAAATCCTCCTGTCTCTGGCAGCACTGTCTGCACTTTCTTGTTTACTGTTTGAAGGGACGAGTACCAAGCCACAAG AACACTTCTTTTGGCCACAGCATAAGCTGATGGTATGTAAGGAACCGATGGGCCATTAAACATGAACTGAACGGTTAAAAGCACAGTCTATGGAACGCTA ATGGAGTCAGCCCCTAAAGCTGTTTGCTTTTTCAGGCTTTGGATTACATGCTTTTAATTTGATTTTAGAATCTGGACACTTTCTATGAATGTAATTCGGC TGAGAAACATGTTGCTGAGATGCAATCCTCAGTGTTCTCTGTATGTAAATCTGTGTATACACCACACGTTACAACTGCATGAGCTTCCTCTCGCACAAGA CCAGCTGGAACTGAGCATGAGACGCTGTCAAATACAGACAAAGGATTTGAGATGTTCTCAATAAAAAGAAAATGTTTCACT

refseq_ADARB1.F4 (forward primer)
refseq_ADARB1.R4 (reverse primer)
Single exon skipping

Frame 0

AAAAAAAAAAAKRPGWRPGLRAARGHGHAAPLR TTNEAERRPARDCGRSVGRACGGPGAARLRLRVE PFRLAWRA*GATEGDTLAKRGVLLTSVLLRYSL SPLAPKEAALGSEQT*S*KNFKTETVSASQETL KSILPWI*KMKKT*VPAALM*RKTAIWTTCPPRM AAHLGLARALSSPMGVVVAPAESGPWRRAAMAT PSTA*RKGGKHQGPSSPRTP*CS*MRSSLVCST HSCPRLGPCTRLCLSCLWR*MARFLRALVPQRKR QNSMLLRRP*GLSFSFLMPLRPTWPWGGPCLST RTSHLTRPTSLTRSSMVLKLLTRRSLPFTWAPM GMTPSVPAGTSACLLPRCLPA*PSLLSLSYHHSH PRVGRIP**S*TNCAQDSSMTSSPRAGRAMPRA SSCLWSWMVSSLKARGETRSLPRPGLRSLPWPP FLTCTWIRRHLASLFPVRVFSCIYRRF*LTLSHA WSWVSLVT*PTTSPPLTLAEKCWLESS*QQAQM LKMPR**VFLQEQNVLMVNT*VIVALH*MTAMQ K*YLGDPCSDFFIHNLSFT*ITKMIKKDPSFRNQ SEGGLG*RRMSSFICTSAPLPVEMPESSHHMSQ SWKNQQIDTQIVKQEDSYGPK*SLVRGRFQCAP MRASKRGTGCCKGSGCSPCPAVTRLHAGTWWASR DPCSAFSWSPFTSRASSWAAFTTGTTFPGPCTS GSPT*RTCHLSTPSTSLCSVASAMQKHGSQGRP PTSVSTGR*ATPLLRSSTPRLGRMSWAARPACVS TRCTVAGCVCTARFPPTYYAPRLPSPTCTMSPS WRQRSTRPPRRVCSQPSSRRGWGPGWRSPPSRT SSHSRPDPGRHDGGCRGLWASSVILQNLTSELGA GAYLGEGVGGHGGPPGVHGCPQHLTSDLGQVRS VGRGWGASGPSIAAWHLSAAAFPLLNRPVTAFN LGLRLEIEFY*VGLP*V*ENRNYFV*NS*INNLF RARNVVYKIGSNCVRSLLCHIILIAKKHLYMEE GGKIEVGNSSLKEIATRLSKLRSLFSVGTSLGS STH*VVTVSP*GADSQHGVAWPCHAHGVPQQ*LC VLQRRDPGPCSPQPPLEASVLLVGSDHGKLFSV YF*VITDNTWPVIPGWPFIQVF*RIFNFYGLEG ITRATAQYMA*VPSVPSSESNGCG*PPEGLHRME VE*FQ*ILILGKCHSFKLLFPALSKTCLKNKKH PSESW*DHVLLA*CRPDIDSPDGSSGLPSAQRA RDGPTTEGVSPGGQERGGRGPCVDHLHQAQRFAP GALLPPLRMKEELREVLCLPVQCPAPRL*RVFR WVSWGHGERLVQTLPHSIHLPQRNPGCWHLCVR DEPRKPEQGQRGVILPPDAGSSDPKTETPWLRRG VCLLMSGAPSTCVHTDLVAARQEGVLLRAHCWG HDRVQRLEHLPHSSLLLHRRG*LSP*SSHSRRL CRSVTTVGFCSGRSRWGSAPAEGEGSVVAGFPPS RLLHTLEKTPCKSVHFYCLDKLYFFLMGIGRWT SFLKICGFWLPSLVLIYSIYIQNYPVCLAFPFC QVIAKVSMIAPCTTPNK*VPHLVGPEQLP*DHVR WHLSGVDSCGLEDRHRAPYPKPSRQEEGSQGNW VLGALGGAAVGRNWVRGALGGAAVGGNWVRGAL GRGLLGGGCEEELGSGSPGRGGCQGELGSGSPGP GQGAAVGRNWFRGALGGAAVGRKVTCRGPEALH CS*DSSSVIRKKINKIQNADSSVRQIGDLSTLI PPF*ALGVHF*TIAVSLTCHSPSSVLDVAFRDLA ENSTQAGT*FFKKKYYILRTF*QVGEERASVVL FCFVLLTKPEVLIPQRHCPSGPLRYSSARDRVL LVGGLRWGGVFCAMRQRQVQMDVVTTFLSSHHLV VRQAHLFPARDAKELQFLF*VLI*LFIIFSYFG EFFVIKSNYFKMCKPVSHKAWISVEFIFIQITI FISRLWNRHFLCEDSVSPCNLTQVH*GGDGSVFT LCTDLRMGLAKLWRLHIRTCPCLKTNTCTVALF PSQTLYPRSRWSAPGIKKENWPSFPPLNSVKL* TCSKDSFLSSPRCVSGKGIVFRVCPVYSVSAP*R VL*QSPWVRSGCTQPRGQWLLGAFRVSSSVHLM PGNRIRENSDLPGSRDWWRWMAGPTRP*LSCKG VSAFSVSCENPPVSGSTVCTFLFTV*RDEYQATR TLLLATA*ADGM*GTDGPLNMN*TVKSTVYGTL MESAPKAVCFFRLWITCF*FDFRIWTLSMNVIR LRNMLLRCNPQCSLYVNLCIHHTLQLHELPLAQD QLELSMRRCQIQTKDLRCSQ*KENVS

Frame 1

RRRRRRRQRRPSGQVGGRGSGPREATATPRRCA QPTRQSAARRETAAEAWGARAEDQARRGCG*EW SLSGWHGELKGQLKETHWPSAEFCLLQSC*DTLS VRSHRRKLPWDQSRHKARKISRQKQSPPVKKPS KVFCHGYRR*RKHEFQQH*CEGKPQSGQRVPQG WQHTWAWRGLSALQWGWWWPRQKAAPGGGQQWPL QVPPEEKEENTRARPPQERPDAAE*DQAWFAVH TPVPDWARARAFVCHVCGGEWPGF*GLWSHKEK GKTPCC*EGLEVFRSVS*CL*GPPGHGEDPVCQH GLHI*PGRLP*HALQWF*NS*QGGASLLRGLQW G*LLQFQRGPQLVCFPGACQPSPASSPCLTTIP TPEWEESRDDLERTAPRTQV*LPLRERGEPCQEL RHVCGRGWSVL*RLGEKQEACQGPGCAVCPGRH F*LALGSDAISPAYSQ*GSSAAFTAGFS*RCLT PGPG*VW*PDRQLLLPSRSQKSAGWSRHDNRHRC *RCQGDKCFYRNKMY*W*IHE*SWPCIK*LPCR NNISEILAQISLYTT*ALLK*QR*SKKIHLSEI RARGV*AEGECPVSSVHQHLSLWRCQNLLTT*AN PGRTSR*TPKS*SKRTATDQNRVW*GDDSSALQ CEHPNVGRGAARGAAAHHVLQ*QDCTLERGGHP GIPAQHFRGAHLLLEHHPGQPLPRGPPFQGHVPA DLQHRGPATSLHPQQAFAQWHQQCRSTAAREGP QLQCQLDGRRLRY*GHQRHDWEG*AGPRVPPV* ARVVLSLDACARQGSLPLTTLQDYQAQRVP*VQA GGKGVPGRQGASVHSLHQGGAGGLGGEAHRAGP VLTHALTRADMMGGAGGCGHPASSSRTSHLNWG QVHTLGRE*GDTGDHQVSTVVPSISHQTWGRCAV WGGDGVRQGPASPPGISLPQHFPF*TVQ*LLSI SVYV*KLSSTE*GFLKFRKIEITLCEILE*IIY SELGMWFIK*EVIVSGHFYATLF*LQKSIYIWRR VGK*R*EIVA*RKSPHVCLNLGLFSP*VPPWVV PHTRL*QSLPEEQTPSMV*RGPVMHMGSRSSDC VSCRGVTQAPVALSLL*KLLYSL*DQIMENFSQF TSK*SQIIHGQ*SQAGHSFRFFKGYLTFMD*KE SRGLLHNTWPKFPLFLPLNRMDVGDRPKAFTGW K*NDFSRYSFLENAIVLNYCFQLYQRHV*KIKSI QVRAGETTCCWRSVGQTLTVLTGAQGCPAPSVH GTAPRQRESAREVRSAAGEGPVWTTSTKLRDLH QVPCCLRSG*KRS*EKCSACQCSAQLQGSRGCSG GSPGAMGRDWCRPYPTAYTCHSEIQGVGTCVSV MSLGNQSRGRGASSSHRTLGAQTPKLKHRGFGG GCAS*CQEPHPRVSTQISSQHGRKGCCLGLIVGD MTGFSG*NICPTAASSSTEEGSCLPEAVTAGVS AAPSPQWGFVQADRAGVLHLQKERGLLSLAFPQ AGSCTL*KKHLVSLCIFIVLINCIFF*WGLGDGL RF*KYVDFGYQV*C*YIPYTYKTTRYVWLFPSV R**LKSA*LLPVPPQISECLTLWGLSSYLETM* GGTFPGWTRAALRTGTGHPIPSRPGRRKAAKATG FWEPWVGQLWGGTGFGEPWAGRLLGGTGFGVPW AGGYWGAAVRRSWVQGALGGVAVRGNWVPGALG RGRGRL*EGTGFGEPWAGRLWGGR*RAGDQRLCT APRTAHL*SEKK*TKYRTLTPP*DRSGTLAL*S LPSERSVCTFRL*LFH*RVTLHPVSLMWLLET* QKIRHKQELDFLRKNITF*GHFDK*GKRGLLLFC FVLFC*LNLKY*FHKDTVPQDHSGTALPGTESC *WEVSGGAVCSVP*GSDRSRWMSSPPSSALITW SYARPTSSQQGTPKNCSFYSES*FNFSSSFPILE NFL*LKAIILKCASQYLTRHGFLWNLFLFK*PY LSPGCGIATFFVKTVSLLVISHRYTEEGTAPSS HCAQI*GWD*RSCGDCTSGPAHVSKQTHVQWLFF LLKHFTPEAGGLPQA*RRKIGHLSHL*IL*NYR LAQKIPFYHPHAV*VERALCSVCVQFTASLPPS VFCDNLPG*GVGAPSPEASGCSGPSV*VLVFT*C RGIELEKTLTCRVPGTGGGGWQVRLDHDLVVRV CRLFQSHVKILLSLAALSALSCLLFEGTSTKPQ EHFFWPQHKLMVCKEPMGH*T*TERLKAQSMER* WSQPLKLFAFSGFGLHAFNLILESGHFL*M*FG *ETCC*DAILSVLCM*ICVYTTRYNCMSFLSHK TSWN*A*DAVKYRQRI*DVLNKKKMFH

Frame 2

GGGGGGGSGGQAARLAAGAPGRARPRPRRAAAH NQRGRAPPGARLRPKRGARVRRTRRGAAAAESG AFQAGMESLRGN*RRHTGQARSSAYFSPAEILS QSARTEGSCLGIRADIKLEKFQDRNSLRQSRNPQ KYFAMDIEDEENMSSSSTDVKENRNLDNVSPKD GSTPGPGEGSQLSNGGGGGPGRKRPLEEGSNGH SKYRLKKRRKTPGPVLPKNALMQLNEIKPGLQYT LLSQTGPVHAPLFVMSVEVNGQVFEGSGPTKKK AKLHAAEKALRSFVQFPNASEAHLAMGRTLSVN TDFTSDQADFPDTLFNGFETPDKAEPPFYVGSNG DDSFSSSGDLSLSASPVPASLAQPPLPVLPPFP PPSGKNPVMILNELRPGLKYDFLSESGESHAKS FVMSVVVDGQFFEGSGRNKKLAKARAAQSALAAI FNLHLDQTPSRQPIPSEGLQLHLPQVLADAVSR LVLGKFGDLTDNFSSPHARRKVLAGVVMTTGTD VKDAKVISVSTGTKCINGEYMSDRGLALNDCHAE IISRRSLLRFLYTQLELYLNNKDDQKRSIFQKS ERGGFRLKENVQFHLYISTSPCGDARIFSPHEP ILEEPADRHPNRKARGQLRTKIESGEGTIPVRSN ASIQTWDGVLQGERLLTMSCSDKIARWNVVGIQ GSLLSIFVEPIYFSSIILGSLYHGDHLSRAMYQ RISNIEDLPPLYTLNKPLLSGISNAEARQPGKAP NFSVNWTVGDSAIEVINATTGKDELGRASRLCK HALYCRWMRVHGKVPSHLLRSKITKPNVYHESK LAAKEYQAAKARLFTAFIKAGLGAWVEKPTEQDQ FSLTP*PGQT*WGVQGAVGIQRHPPEPHI*TGG RCIPWGGSRGTRGTTRCPRLSPASHIRPGAGAQ CGEGMGCVRAQHRRLASLCRSISPSEPSSDCFQS RFTFRN*VLLSRASLSLGK*KLLCVKFLNK*FI QS*ECGL*NRK*LCQVTFMPHYFNCKKASIYGG GWENRGRK**PKGNRHTSV*T*VSFLRRYLPG*F HTLGCNSLSLRSRLPAWCSVALSCTWGPAAVTV CPAEA*PRPL*PSASSRSFCTPCRIRSWKTFLS LLLSNHR*YMASNPRLAIHSGFLKDI*LLWTRRN HEGYCTIHGLSSLCSFL*IEWMWVTARRPSQDG SRMISVDTHSWKMP*F*IIVSSFIKDMFEK*KA SK*ELVRPRAAGVV*ARH*QS*RELRAAQRPACT GRPHDRGSQPGRSGARRARALCGPPPPSSEICT RCLVASAQDERGAERSALPASAVPSSKALEGVQ VGLLGPWGEIGADLTPQHTPATAKSRVLAPVCP* *A*ETRAGAEGRHPPTGRWELRPQN*NTVASAG GVPPDVRSPIHVCPHRSRRSTAGRGAA*GSLLG T*PGSAARTSAPQQPPPPPKRVVVSLKQSQQASL PLRHHSGVLFRQIALGFCTCRRRGVCCRWLSPK QALAHSRKNTL*VCAFLLS**IVFFSNGDWEMD FVFKNMWILVTKFSVNIFHIHTKLPGMSGFSLLS GNS*SQHDCSLYHPK*VSASPCGA*AATLRPCE VAPFRGGLVRP*GQAQGTLSQAVQAGGRQPRQL GSGSPGWGSCGEELGSGSPGRGGCWGELGSGCPG QGATGGRL*GGVGFREPWAGWLSGGTGFREPWA GAGGGCRKELVSGSPGRGGCGEEGDVQGTRGSA LLLGQLICNQKKNKQNTER*LLRETDRGP*HFNP SLLSARCALLDYSCFIDVSLSIQCP*CGF*RLS RKFDTSRNLIF*EKILHFEDILTSRGREGFCCF VLFCFVN*T*SINSTKTLSLRTTQVQLCQGQSPA SGRSQVGRCVLCHEAATGPDGCRHHLPQLSSPG RTPGPPLPSKGRQRTAVFILSLNLTFHHLFLFW RIFCN*KQLF*NVQASISQGMDFCGIYFYSNNHI YLQAVESPLSL*RQCLSL*SHTGTLRRGRLRLH IVHRSEDGISEAVETAHPDLPMSQNKHMYSGSF SFSNTLPQKQVVCPRHKEGKLAIFPTSKFCKIID LLKRFLFIIPTLCKWKGHCVPCVSSLQRLCPLA CFVTISLGEEWVHPAPRPVVARGLPCEF*CSLD AGE*N*RKL*PAGFQGLVEVDGRSDSTMT*L*GC VGFFSLM*KSSCLWQHCLHFLVYCLKGRVPSHK NTSFGHSIS*WYVRNRWAIKHELNG*KHSLWNA NGVSP*SCLLFQALDYMLLI*F*NLDTFYECNSA EKHVAEMQSSVFSVCKSVYTPHVTTA*ASSRTR PAGTEHETLSNTDKGFEMFSIKRKCFT

Sequence NM_015834

refseq_ADARB1.F4 (forward primer)
refseq_ADARB1.R4 (reverse primer)
Single exon skipping

Frame 0

Frame 1

Frame 2

Sequence NM_015833

GCGGCGGCGGCGGCGGCGGCGGCAGCGGCGGCCAAGCGGCCAGGTTGGCGGCCGGGGCTCCGGGCCGCGCGAGGCCACGGCCACGCCGCGCCGCTGCGCA CAACCAACGAGGCAGAGCGCCGCCCGGCGCGAGACTGCGGCCGAAGCGTGGGGCGCGCGTGCGGAGGACCAGGCGCGGCGCGGCTGCGGCTGAGAGTGGA GCCTTTCAGGCTGGCATGGAGAGCTTAAGGGGCAACTGAAGGAGACACACTGGCCAAGCGCGGAGTTCTGCTTACTTCAGTCCTGCTGAGATACTCTCTC AGTCCGCTCGCACCGAAGGAAGCTGCCTTGGGATCAGAGCAGACATAAAGCTAGAAAAATTTCAAGACAGAAACAGTCTCCGCCAGTCAAGAAACCCTCA AAAGTATTTTGCCATGGATATAGAAGATGAAGAAAACATGAGTTCCAGCAGCACTGATGTGAAGGAAAACCGCAATCTGGACAACGTGTCCCCCAAGGAT GGCAGCACACCTGGGCCTGGCGAGGGCTCTCAGCTCTCCAATGGGGGTGGTGGTGGCCCCGGCAGAAAGCGGCCCCTGGAGGAGGGCAGCAATGGCCACT CCAAGTACCGCCTGAAGAAAAGGAGGAAAACACCAGGGCCCGTCCTCCCCAAGAACGCCCTGATGCAGCTGAATGAGATCAAGCCTGGTTTGCAGTACAC ACTCCTGTCCCAGACTGGGCCCGTGCACGCGCCTTTGTTTGTCATGTCTGTGGAGGTGAATGGCCAGGTTTTTGAGGGCTCTGGTCCCACAAAGAAAAAG GCAAAACTCCATGCTGCTGAGAAGGCCTTGAGGTCTTTCGTTCAGTTTCCTAATGCCTCTGAGGCCCACCTGGCCATGGGGAGGACCCTGTCTGTCAACA CGGACTTCACATCTGACCAGGCCGACTTCCCTGACACGCTCTTCAATGGTTTTGAAACTCCTGACAAGGCGGAGCCTCCCTTTTACGTGGGCTCCAATGG GGATGACTCCTTCAGTTCCAGCGGGGACCTCAGCTTGTCTGCTTCCCCGGTGCCTGCCAGCCTAGCCCAGCCTCCTCTCCCTGTCTTACCACCATTCCCA CCCCCGAGTGGGAAGAATCCCGTGATGATCTTGAACGAACTGCGCCCAGGACTCAAGTATGACTTCCTCTCCGAGAGCGGGGAGAGCCATGCCAAGAGCT TCGTCATGTCTGTGGTCGTGGATGGTCAGTTCTTTGAAGGCTCGGGGAGAAACAAGAAGCTTGCCAAGGCCCGGGCTGCGCAGTCTGCCCTGGCCGCCAT TTTTAACTTGCACTTGGATCAGACGCCATCTCGCCAGCCTATTCCCAGTGAGGGTCTTCAGCTGCATTTACCGCAGGTTTTAGCTGACGCTGTCTCACGC CTGGTCCTGGGTAAGTTTGGTGACCTGACCGACAACTTCTCCTCCCCTCACGCTCGCAGAAAAGTGCTGGCTGGAGTCGTCATGACAACAGGCACAGATG TTAAAGATGCCAAGGTGATAAGTGTTTCTACAGGAACAAAATGTATTAATGGTGAATACATGAGTGATCGTGGCCTTGCATTAAATGACTGCCATGCAGA AATAATATCTCGGAGATCCTTGCTCAGATTTCTTTATACACAACTTGAGCTTTACTTAAATAACAAAGATGATCAAAAAAGATCCATCTTTCAGAAATCA GAGCGAGGGGGGTTTAGGCTGAAGGAGAATGTCCAGTTTCATCTGTACATCAGCACCTCTCCCTGTGGAGATGCCAGAATCTTCTCACCACATGAGCCAA TCCTGGAAGGGTCTCGCTCTTACACCCAGGCTGGAGTGCAGTGGTGCAATCATGGCTCACTGCAGCCTCGACCTCCTGGGCTCTTAAGCGATCCTTCCAC CTCAACCTTCCAAGGAGCTGGGACTACAGAACCAGCAGATAGACACCCAAATCGTAAAGCAAGAGGACAGCTACGGACCAAAATAGAGTCTGGTGAGGGG ACGATTCCAGTGCGCTCCAATGCGAGCATCCAAACGTGGGACGGGGTGCTGCAAGGGGAGCGGCTGCTCACCATGTCCTGCAGTGACAAGATTGCACGCT GGAACGTGGTGGGCATCCAGGGATCCCTGCTCAGCATTTTCGTGGAGCCCATTTACTTCTCGAGCATCATCCTGGGCAGCCTTTACCACGGGGACCACCT TTCCAGGGCCATGTACCAGCGGATCTCCAACATAGAGGACCTGCCACCTCTCTACACCCTCAACAAGCCTTTGCTCAGTGGCATCAGCAATGCAGAAGCA CGGCAGCCAGGGAAGGCCCCCAACTTCAGTGTCAACTGGACGGTAGGCGACTCCGCTATTGAGGTCATCAACGCCACGACTGGGAAGGATGAGCTGGGCC GCGCGTCCCGCCTGTGTAAGCACGCGTTGTACTGTCGCTGGATGCGTGTGCACGGCAAGGTTCCCTCCCACTTACTACGCTCCAAGATTACCAAGCCCAA CGTGTACCATGAGTCCAAGCTGGCGGCAAAGGAGTACCAGGCCGCCAAGGCGCGTCTGTTCACAGCCTTCATCAAGGCGGGGCTGGGGGCCTGGGTGGAG AAGCCCACCGAGCAGGACCAGTTCTCACTCACGCCCTGACCCGGGCAGACATGATGGGGGGTGCAGGGGGCTGTGGGCATCCAGCGTCATCCTCCAGAAC CTCACATCTGAACTGGGGGCAGGTGCATACCTTGGGGAGGGAGTAGGGGGACACGGGGGACCACCAGGTGTCCACGGTTGTCCCCAGCATCTCACATCAG ACCTGGGGCAGGTGCGCAGTGTGGGGAGGGGATGGGGTGCGTCAGGGCCCAGCATCGCCGCCTGGCATCTCTCTGCCGCAGCATTTCCCCTTCTGAACCG TCCAGTGACTGCTTTCAATCTCGGTTTACGTTTAGAAATTGAGTTCTACTGAGTAGGGCTTCCTTAAGTTTAGGAAAATAGAAATTACTTTGTGTGAAAT TCTTGAATAAATAATTTATTCAGAGCTAGGAATGTGGTTTATAAAATAGGAAGTAATTGTGTCAGGTCACTTTTATGCCACATTATTTTAATTGCAAAAA AGCATCTATATATGGAGGAGGGTGGGAAAATAGAGGTAGGAAATAGTAGCCTAAAGGAAATCGCCACACGTCTGTCTAAACTTAGGTCTCTTTTCTCCGT AGGTACCTCCCTGGGTAGTTCCACACACTAGGTTGTAACAGTCTCTCCCTGAGGAGCAGACTCCCAGCATGGTGTAGCGTGGCCCTGTCATGCACATGGG GTCCCGCAGCAGTGACTGTGTGTCCTGCAGAGGCGTGACCCAGGCCCCTGTAGCCCTCAGCCTCCTCTAGAAGCTTCTGTACTCCTTGTAGGATCAGATC ATGGAAAACTTTTCTCAGTTTACTTCTAAGTAATCACAGATAATACATGGCCAGTAATCCCAGGCTGGCCATTCATTCAGGTTTTTTAAAGGATATTTAA CTTTTATGGACTAGAAGGAATCACGAGGGCTACTGCACAATACATGGCCTAAGTTCCCTCTGTTCCTTCCTCTGAATCGAATGGATGTGGGTGACCGCCC GAAGGCCTTCACAGGATGGAAGTAGAATGATTTCAGTAGATACTCATTCTTGGAAAATGCCATAGTTTTAAATTATTGTTTCCAGCTTTATCAAAGACAT GTTTGAAAAATAAAAAGCATCCAAGTGAGAGCTGGTGAGACCACGTGCTGCTGGCGTAGTGTAGGCCAGACATTGACAGTCCTGACGGGAGCTCAGGGCT GCCCAGCGCCCAGCGTGCACGGGACGGCCCCACGACAGAGGGAGTCAGCCCGGGAGGTCAGGAGCGCGGCGGGCGAGGGCCCTGTGTGGACCACCTCCAC CAAGCTCAGAGATTTGCACCAGGTGCCTTGTTGCCTCCGCTCAGGATGAAAGAGGAGCTGAGAGAAGTGCTCTGCCTGCCAGTGCAGTGCCCAGCTCCAA GGCTCTAGAGGGTGTTCAGGTACACTGAGGAGGGGACGGCTCCGTCTTCACATTGTGCACAGATCTGAGGATGGGATTAGCGAAGCTGTGGAGACTGCAC ATCCGGACCTGCCCATGTCTCAAAACAAACACATGTACAGTGGCTCTTTTTCCTTCTCAAACACTTTACCCCAGAAGCAGGTGGTCTGCCCCAGGCATAA AGAAGGAAAATTGGCCATCTTTCCCACCTCTAAATTCTGTAAAATTATAGACTTGCTCAAAAGATTCCTTTTTATCATCCCCACGCTGTGTAAGTGGAAA GGGCATTGTGTTCCGTGTGTGTCCAGTTTACAGCGTCTCTGCCCCCTAGCGTGTTTTGTGACAATCTCCCTGGGTGAGGAGTGGGTGCACCCAGCCCCGA GGCCAGTGGTTGCTCGGGGCCTTCCGTGTGAGTTCTAGTGTTCACTTGATGCCGGGGAATAGAATTAGAGAAAACTCTGACCTGCCGGGTTCCAGGGACT GGTGGAGGTGGATGGCAGGTCCGACTCGACCATGACTTAGTTGTAAGGGTGTGTCGGCTTTTTCAGTCTCATGTGAAAATCCTCCTGTCTCTGGCAGCAC TGTCTGCACTTTCTTGTTTACTGTTTGAAGGGACGAGTACCAAGCCACAAGAACACTTCTTTTGGCCACAGCATAAGCTGATGGTATGTAAGGAACCGAT GGGCCATTAAACATGAACTGAACGGTTAAAAGCACAGTCTATGGAACGCTAATGGAGTCAGCCCCTAAAGCTGTTTGCTTTTTCAGGCTTTGGATTACAT GCTTTTAATTTGATTTTAGAATCTGGACACTTTCTATGAATGTAATTCGGCTGAGAAACATGTTGCTGAGATGCAATCCTCAGTGTTCTCTGTATGTAAA TCTGTGTATACACCACACGTTACAACTGCATGAGCTTCCTCTCGCACAAGACCAGCTGGAACTGAGCATGAGACGCTGTCAAATACAGACAAAGGATTTG AGATGTTCTCAATAAAAAGAAAATGTTTCACT

refseq_ADARB1.F4 (forward primer)
refseq_ADARB1.R4 (reverse primer)
Single exon skipping

Frame 0

AAAAAAAAAAAKRPGWRPGLRAARGHGHAAPLR TTNEAERRPARDCGRSVGRACGGPGAARLRLRVE PFRLAWRA*GATEGDTLAKRGVLLTSVLLRYSL SPLAPKEAALGSEQT*S*KNFKTETVSASQETL KSILPWI*KMKKT*VPAALM*RKTAIWTTCPPRM AAHLGLARALSSPMGVVVAPAESGPWRRAAMAT PSTA*RKGGKHQGPSSPRTP*CS*MRSSLVCST HSCPRLGPCTRLCLSCLWR*MARFLRALVPQRKR QNSMLLRRP*GLSFSFLMPLRPTWPWGGPCLST RTSHLTRPTSLTRSSMVLKLLTRRSLPFTWAPM GMTPSVPAGTSACLLPRCLPA*PSLLSLSYHHSH PRVGRIP**S*TNCAQDSSMTSSPRAGRAMPRA SSCLWSWMVSSLKARGETRSLPRPGLRSLPWPP FLTCTWIRRHLASLFPVRVFSCIYRRF*LTLSHA WSWVSLVT*PTTSPPLTLAEKCWLESS*QQAQM LKMPR**VFLQEQNVLMVNT*VIVALH*MTAMQ K*YLGDPCSDFFIHNLSFT*ITKMIKKDPSFRNQ SEGGLG*RRMSSFICTSAPLPVEMPESSHHMSQ SWKGLALTPRLECSGAIMAHCSLDLLGS*AILP PQPSKELGLQNQQIDTQIVKQEDSYGPK*SLVRG RFQCAPMRASKRGTGCCKGSGCSPCPAVTRLHA GTWWASRDPCSAFSWSPFTSRASSWAAFTTGTT FPGPCTSGSPT*RTCHLSTPSTSLCSVASAMQKH GSQGRPPTSVSTGR*ATPLLRSSTPRLGRMSWA ARPACVSTRCTVAGCVCTARFPPTYYAPRLPSP TCTMSPSWRQRSTRPPRRVCSQPSSRRGWGPGWR SPPSRTSSHSRPDPGRHDGGCRGLWASSVILQN LTSELGAGAYLGEGVGGHGGPPGVHGCPQHLTS DLGQVRSVGRGWGASGPSIAAWHLSAAAFPLLNR PVTAFNLGLRLEIEFY*VGLP*V*ENRNYFV*N S*INNLFRARNVVYKIGSNCVRSLLCHIILIAK KHLYMEEGGKIEVGNSSLKEIATRLSKLRSLFSV GTSLGSSTH*VVTVSP*GADSQHGVAWPCHAHG VPQQ*LCVLQRRDPGPCSPQPPLEASVLLVGSD HGKLFSVYF*VITDNTWPVIPGWPFIQVF*RIFN FYGLEGITRATAQYMA*VPSVPSSESNGCG*PP EGLHRMEVE*FQ*ILILGKCHSFKLLFPALSKT CLKNKKHPSESW*DHVLLA*CRPDIDSPDGSSGL PSAQRARDGPTTEGVSPGGQERGGRGPCVDHLH QAQRFAPGALLPPLRMKEELREVLCLPVQCPAP RL*RVFRYTEEGTAPSSHCAQI*GWD*RSCGDCT SGPAHVSKQTHVQWLFFLLKHFTPEAGGLPQA* RRKIGHLSHL*IL*NYRLAQKIPFYHPHAV*VE RALCSVCVQFTASLPPSVFCDNLPG*GVGAPSPE ASGCSGPSV*VLVFT*CRGIELEKTLTCRVPGT GGGGWQVRLDHDLVVRVCRLFQSHVKILLSLAA LSALSCLLFEGTSTKPQEHFFWPQHKLMVCKEPM GH*T*TERLKAQSMER*WSQPLKLFAFSGFGLH AFNLILESGHFL*M*FG*ETCC*DAILSVLCM* ICVYTTRYNCMSFLSHKTSWN*A*DAVKYRQRI* DVLNKKKMFH

Frame 1

RRRRRRRQRRPSGQVGGRGSGPREATATPRRCA QPTRQSAARRETAAEAWGARAEDQARRGCG*EW SLSGWHGELKGQLKETHWPSAEFCLLQSC*DTLS VRSHRRKLPWDQSRHKARKISRQKQSPPVKKPS KVFCHGYRR*RKHEFQQH*CEGKPQSGQRVPQG WQHTWAWRGLSALQWGWWWPRQKAAPGGGQQWPL QVPPEEKEENTRARPPQERPDAAE*DQAWFAVH TPVPDWARARAFVCHVCGGEWPGF*GLWSHKEK GKTPCC*EGLEVFRSVS*CL*GPPGHGEDPVCQH GLHI*PGRLP*HALQWF*NS*QGGASLLRGLQW G*LLQFQRGPQLVCFPGACQPSPASSPCLTTIP TPEWEESRDDLERTAPRTQV*LPLRERGEPCQEL RHVCGRGWSVL*RLGEKQEACQGPGCAVCPGRH F*LALGSDAISPAYSQ*GSSAAFTAGFS*RCLT PGPG*VW*PDRQLLLPSRSQKSAGWSRHDNRHRC *RCQGDKCFYRNKMY*W*IHE*SWPCIK*LPCR NNISEILAQISLYTT*ALLK*QR*SKKIHLSEI RARGV*AEGECPVSSVHQHLSLWRCQNLLTT*AN PGRVSLLHPGWSAVVQSWLTAASTSWALKRSFH LNLPRSWDYRTSR*TPKS*SKRTATDQNRVW*G DDSSALQCEHPNVGRGAARGAAAHHVLQ*QDCTL ERGGHPGIPAQHFRGAHLLLEHHPGQPLPRGPP FQGHVPADLQHRGPATSLHPQQAFAQWHQQCRS TAAREGPQLQCQLDGRRLRY*GHQRHDWEG*AGP RVPPV*ARVVLSLDACARQGSLPLTTLQDYQAQ RVP*VQAGGKGVPGRQGASVHSLHQGGAGGLGG EAHRAGPVLTHALTRADMMGGAGGCGHPASSSRT SHLNWGQVHTLGRE*GDTGDHQVSTVVPSISHQ TWGRCAVWGGDGVRQGPASPPGISLPQHFPF*T VQ*LLSISVYV*KLSSTE*GFLKFRKIEITLCEI LE*IIYSELGMWFIK*EVIVSGHFYATLF*LQK SIYIWRRVGK*R*EIVA*RKSPHVCLNLGLFSP *VPPWVVPHTRL*QSLPEEQTPSMV*RGPVMHMG SRSSDCVSCRGVTQAPVALSLL*KLLYSL*DQI MENFSQFTSK*SQIIHGQ*SQAGHSFRFFKGYL TFMD*KESRGLLHNTWPKFPLFLPLNRMDVGDRP KAFTGWK*NDFSRYSFLENAIVLNYCFQLYQRH V*KIKSIQVRAGETTCCWRSVGQTLTVLTGAQG CPAPSVHGTAPRQRESAREVRSAAGEGPVWTTST KLRDLHQVPCCLRSG*KRS*EKCSACQCSAQLQ GSRGCSGTLRRGRLRLHIVHRSEDGISEAVETA HPDLPMSQNKHMYSGSFSFSNTLPQKQVVCPRHK EGKLAIFPTSKFCKIIDLLKRFLFIIPTLCKWK GHCVPCVSSLQRLCPLACFVTISLGEEWVHPAP RPVVARGLPCEF*CSLDAGE*N*RKL*PAGFQGL VEVDGRSDSTMT*L*GCVGFFSLM*KSSCLWQH CLHFLVYCLKGRVPSHKNTSFGHSIS*WYVRNR WAIKHELNG*KHSLWNANGVSP*SCLLFQALDYM LLI*F*NLDTFYECNSAEKHVAEMQSSVFSVCK SVYTPHVTTA*ASSRTRPAGTEHETLSNTDKGF EMFSIKRKCFT

Frame 2

GGGGGGGSGGQAARLAAGAPGRARPRPRRAAAH NQRGRAPPGARLRPKRGARVRRTRRGAAAAESG AFQAGMESLRGN*RRHTGQARSSAYFSPAEILS QSARTEGSCLGIRADIKLEKFQDRNSLRQSRNPQ KYFAMDIEDEENMSSSSTDVKENRNLDNVSPKD GSTPGPGEGSQLSNGGGGGPGRKRPLEEGSNGH SKYRLKKRRKTPGPVLPKNALMQLNEIKPGLQYT LLSQTGPVHAPLFVMSVEVNGQVFEGSGPTKKK AKLHAAEKALRSFVQFPNASEAHLAMGRTLSVN TDFTSDQADFPDTLFNGFETPDKAEPPFYVGSNG DDSFSSSGDLSLSASPVPASLAQPPLPVLPPFP PPSGKNPVMILNELRPGLKYDFLSESGESHAKS FVMSVVVDGQFFEGSGRNKKLAKARAAQSALAAI FNLHLDQTPSRQPIPSEGLQLHLPQVLADAVSR LVLGKFGDLTDNFSSPHARRKVLAGVVMTTGTD VKDAKVISVSTGTKCINGEYMSDRGLALNDCHAE IISRRSLLRFLYTQLELYLNNKDDQKRSIFQKS ERGGFRLKENVQFHLYISTSPCGDARIFSPHEP ILEGSRSYTQAGVQWCNHGSLQPRPPGLLSDPST STFQGAGTTEPADRHPNRKARGQLRTKIESGEG TIPVRSNASIQTWDGVLQGERLLTMSCSDKIAR WNVVGIQGSLLSIFVEPIYFSSIILGSLYHGDHL SRAMYQRISNIEDLPPLYTLNKPLLSGISNAEA RQPGKAPNFSVNWTVGDSAIEVINATTGKDELG RASRLCKHALYCRWMRVHGKVPSHLLRSKITKPN VYHESKLAAKEYQAAKARLFTAFIKAGLGAWVE KPTEQDQFSLTP*PGQT*WGVQGAVGIQRHPPE PHI*TGGRCIPWGGSRGTRGTTRCPRLSPASHIR PGAGAQCGEGMGCVRAQHRRLASLCRSISPSEP SSDCFQSRFTFRN*VLLSRASLSLGK*KLLCVK FLNK*FIQS*ECGL*NRK*LCQVTFMPHYFNCKK ASIYGGGWENRGRK**PKGNRHTSV*T*VSFLR RYLPG*FHTLGCNSLSLRSRLPAWCSVALSCTW GPAAVTVCPAEA*PRPL*PSASSRSFCTPCRIRS WKTFLSLLLSNHR*YMASNPRLAIHSGFLKDI* LLWTRRNHEGYCTIHGLSSLCSFL*IEWMWVTA RRPSQDGSRMISVDTHSWKMP*F*IIVSSFIKDM FEK*KASK*ELVRPRAAGVV*ARH*QS*RELRA AQRPACTGRPHDRGSQPGRSGARRARALCGPPP PSSEICTRCLVASAQDERGAERSALPASAVPSSK ALEGVQVH*GGDGSVFTLCTDLRMGLAKLWRLH IRTCPCLKTNTCTVALFPSQTLYPRSRWSAPGI KKENWPSFPPLNSVKL*TCSKDSFLSSPRCVSGK GIVFRVCPVYSVSAP*RVL*QSPWVRSGCTQPR GQWLLGAFRVSSSVHLMPGNRIRENSDLPGSRD WWRWMAGPTRP*LSCKGVSAFSVSCENPPVSGST VCTFLFTV*RDEYQATRTLLLATA*ADGM*GTD GPLNMN*TVKSTVYGTLMESAPKAVCFFRLWIT CF*FDFRIWTLSMNVIRLRNMLLRCNPQCSLYVN LCIHHTLQLHELPLAQDQLELSMRRCQIQTKDL RCSQ*KENVS

Sequence NM_001033049

GCGGCGGCGGCGGCGGCGGCGGCAGCGGCGGCCAAGCGGCCAGGTTGGCGGCCGGGGCTCCGGGCCGCGCGAGGCCACGGCCACGCCGCGCCGCTGCGCA CAACCAACGAGGCAGAGCGCCGCCCGGCGCGAGACTGCGGCCGAAGCGTGGGGCGCGCGTGCGGAGGACCAGGCGCGGCGCGGCTGCGGCTGAGAGTGGA GCCTTTCAGGCTGGCATGGAGAGCTTAAGGGGCAACTGAAGGAGACACACTGGCCAAGCGCGGAGTTCTGCTTACTTCAGTCCTGCTGAGATACTCTCTC AGTCCGCTCGCACCGAAGGAAGCTGCCTTGGGATCAGAGCAGACATAAAGCTAGAAAAATTTCAAGATGAAATTGAAATGGCCAATGAGCACACCCTCAT TCATCCAGCGAGCATTGAGGACCCCCTAGAGGCCAGGCCCATGAGTGATGAAGATCCCGAGGATGAAGACGCCTTGCCAGCCAGACAGAAACAGTCTCCG CCAGTCAAGAAACCCTCAAAAGTATTTTGCCATGGATATAGAAGATGAAGAAAACATGAGTTCCAGCAGCACTGATGTGAAGGAAAACCGCAATCTGGAC AACGTGTCCCCCAAGGATGGCAGCACACCTGGGCCTGGCGAGGGCTCTCAGCTCTCCAATGGGGGTGGTGGTGGCCCCGGCAGAAAGCGGCCCCTGGAGG AGGGCAGCAATGGCCACTCCAAGTACCGCCTGAAGAAAAGGAGGAAAACACCAGGGCCCGTCCTCCCCAAGAACGCCCTGATGCAGCTGAATGAGATCAA GCCTGGTTTGCAGTACACACTCCTGTCCCAGACTGGGCCCGTGCACGCGCCTTTGTTTGTCATGTCTGTGGAGGTGAATGGCCAGGTTTTTGAGGGCTCT GGTCCCACAAAGAAAAAGGCAAAACTCCATGCTGCTGAGAAGGCCTTGAGGTCTTTCGTTCAGTTTCCTAATGCCTCTGAGGCCCACCTGGCCATGGGGA GGACCCTGTCTGTCAACACGGACTTCACATCTGACCAGGCCGACTTCCCTGACACGCTCTTCAATGGTTTTGAAACTCCTGACAAGGCGGAGCCTCCCTT TTACGTGGGCTCCAATGGGGATGACTCCTTCAGTTCCAGCGGGGACCTCAGCTTGTCTGCTTCCCCGGTGCCTGCCAGCCTAGCCCAGCCTCCTCTCCCT GTCTTACCACCATTCCCACCCCCGAGTGGGAAGAATCCCGTGATGATCTTGAACGAACTGCGCCCAGGACTCAAGTATGACTTCCTCTCCGAGAGCGGGG AGAGCCATGCCAAGAGCTTCGTCATGTCTGTGGTCGTGGATGGTCAGTTCTTTGAAGGCTCGGGGAGAAACAAGAAGCTTGCCAAGGCCCGGGCTGCGCA GTCTGCCCTGGCCGCCATTTTTAACTTGCACTTGGATCAGACGCCATCTCGCCAGCCTATTCCCAGTGAGGGTCTTCAGCTGCATTTACCGCAGGTTTTA GCTGACGCTGTCTCACGCCTGGTCCTGGGTAAGTTTGGTGACCTGACCGACAACTTCTCCTCCCCTCACGCTCGCAGAAAAGTGCTGGCTGGAGTCGTCA TGACAACAGGCACAGATGTTAAAGATGCCAAGGTGATAAGTGTTTCTACAGGAACAAAATGTATTAATGGTGAATACATGAGTGATCGTGGCCTTGCATT AAATGACTGCCATGCAGAAATAATATCTCGGAGATCCTTGCTCAGATTTCTTTATACACAACTTGAGCTTTACTTAAATAACAAAGATGATCAAAAAAGA TCCATCTTTCAGAAATCAGAGCGAGGGGGGTTTAGGCTGAAGGAGAATGTCCAGTTTCATCTGTACATCAGCACCTCTCCCTGTGGAGATGCCAGAATCT TCTCACCACATGAGCCAATCCTGGAAGAACCAGCAGATAGACACCCAAATCGTAAAGCAAGAGGACAGCTACGGACCAAAATAGAGTCTGGTGAGGGGAC GATTCCAGTGCGCTCCAATGCGAGCATCCAAACGTGGGACGGGGTGCTGCAAGGGGAGCGGCTGCTCACCATGTCCTGCAGTGACAAGATTGCACGCTGG AACGTGGTGGGCATCCAGGGATCCCTGCTCAGCATTTTCGTGGAGCCCATTTACTTCTCGAGCATCATCCTGGGCAGCCTTTACCACGGGGACCACCTTT CCAGGGCCATGTACCAGCGGATCTCCAACATAGAGGACCTGCCACCTCTCTACACCCTCAACAAGCCTTTGCTCAGTGGCATCAGCAATGCAGAAGCACG GCAGCCAGGGAAGGCCCCCAACTTCAGTGTCAACTGGACGGTAGGCGACTCCGCTATTGAGGTCATCAACGCCACGACTGGGAAGGATGAGCTGGGCCGC GCGTCCCGCCTGTGTAAGCACGCGTTGTACTGTCGCTGGATGCGTGTGCACGGCAAGGTTCCCTCCCACTTACTACGCTCCAAGATTACCAAGCCCAACG TGTACCATGAGTCCAAGCTGGCGGCAAAGGAGTACCAGGCCGCCAAGGCGCGTCTGTTCACAGCCTTCATCAAGGCGGGGCTGGGGGCCTGGGTGGAGAA GCCCACCGAGCAGGACCAGTTCTCACTCACGCCCTGACCCGGGCAGACATGATGGGGGGTGCAGGGGGCTGTGGGCATCCAGCGTCATCCTCCAGAACCT CACATCTGAACTGGGGGCAGGTGCATACCTTGGGGAGGGAGTAGGGGGACACGGGGGACCACCAGGTGTCCACGGTTGTCCCCAGCATCTCACATCAGAC CTGGGGCAGGTGCGCAGTGTGGGGAGGGGATGGGGTGCGTCAGGGCCCAGCATCGCCGCCTGGCATCTCTCTGCCGCAGCATTTCCCCTTCTGAACCGTC CAGTGACTGCTTTCAATCTCGGTTTACGTTTAGAAATTGAGTTCTACTGAGTAGGGCTTCCTTAAGTTTAGGAAAATAGAAATTACTTTGTGTGAAATTC TTGAATAAATAATTTATTCAGAGCTAGGAATGTGGTTTATAAAATAGGAAGTAATTGTGTCAGGTCACTTTTATGCCACATTATTTTAATTGCAAAAAAG CATCTATATATGGAGGAGGGTGGGAAAATAGAGGTAGGAAATAGTAGCCTAAAGGAAATCGCCACACGTCTGTCTAAACTTAGGTCTCTTTTCTCCGTAG GTACCTCCCTGGGTAGTTCCACACACTAGGTTGTAACAGTCTCTCCCTGAGGAGCAGACTCCCAGCATGGTGTAGCGTGGCCCTGTCATGCACATGGGGT CCCGCAGCAGTGACTGTGTGTCCTGCAGAGGCGTGACCCAGGCCCCTGTAGCCCTCAGCCTCCTCTAGAAGCTTCTGTACTCCTTGTAGGATCAGATCAT GGAAAACTTTTCTCAGTTTACTTCTAAGTAATCACAGATAATACATGGCCAGTAATCCCAGGCTGGCCATTCATTCAGGTTTTTTAAAGGATATTTAACT TTTATGGACTAGAAGGAATCACGAGGGCTACTGCACAATACATGGCCTAAGTTCCCTCTGTTCCTTCCTCTGAATCGAATGGATGTGGGTGACCGCCCGA AGGCCTTCACAGGATGGAAGTAGAATGATTTCAGTAGATACTCATTCTTGGAAAATGCCATAGTTTTAAATTATTGTTTCCAGCTTTATCAAAGACATGT TTGAAAAATAAAAAGCATCCAAGTGAGAGCTGGTGAGACCACGTGCTGCTGGCGTAGTGTAGGCCAGACATTGACAGTCCTGACGGGAGCTCAGGGCTGC CCAGCGCCCAGCGTGCACGGGACGGCCCCACGACAGAGGGAGTCAGCCCGGGAGGTCAGGAGCGCGGCGGGCGAGGGCCCTGTGTGGACCACCTCCACCA AGCTCAGAGATTTGCACCAGGTGCCTTGTTGCCTCCGCTCAGGATGAAAGAGGAGCTGAGAGAAGTGCTCTGCCTGCCAGTGCAGTGCCCAGCTCCAAGG CTCTAGAGGGTGTTCAGGTACACTGAGGAGGGGACGGCTCCGTCTTCACATTGTGCACAGATCTGAGGATGGGATTAGCGAAGCTGTGGAGACTGCACAT CCGGACCTGCCCATGTCTCAAAACAAACACATGTACAGTGGCTCTTTTTCCTTCTCAAACACTTTACCCCAGAAGCAGGTGGTCTGCCCCAGGCATAAAG AAGGAAAATTGGCCATCTTTCCCACCTCTAAATTCTGTAAAATTATAGACTTGCTCAAAAGATTCCTTTTTATCATCCCCACGCTGTGTAAGTGGAAAGG GCATTGTGTTCCGTGTGTGTCCAGTTTACAGCGTCTCTGCCCCCTAGCGTGTTTTGTGACAATCTCCCTGGGTGAGGAGTGGGTGCACCCAGCCCCGAGG CCAGTGGTTGCTCGGGGCCTTCCGTGTGAGTTCTAGTGTTCACTTGATGCCGGGGAATAGAATTAGAGAAAACTCTGACCTGCCGGGTTCCAGGGACTGG TGGAGGTGGATGGCAGGTCCGACTCGACCATGACTTAGTTGTAAGGGTGTGTCGGCTTTTTCAGTCTCATGTGAAAATCCTCCTGTCTCTGGCAGCACTG TCTGCACTTTCTTGTTTACTGTTTGAAGGGACGAGTACCAAGCCACAAGAACACTTCTTTTGGCCACAGCATAAGCTGATGGTATGTAAGGAACCGATGG GCCATTAAACATGAACTGAACGGTTAAAAGCACAGTCTATGGAACGCTAATGGAGTCAGCCCCTAAAGCTGTTTGCTTTTTCAGGCTTTGGATTACATGC TTTTAATTTGATTTTAGAATCTGGACACTTTCTATGAATGTAATTCGGCTGAGAAACATGTTGCTGAGATGCAATCCTCAGTGTTCTCTGTATGTAAATC TGTGTATACACCACACGTTACAACTGCATGAGCTTCCTCTCGCACAAGACCAGCTGGAACTGAGCATGAGACGCTGTCAAATACAGACAAAGGATTTGAG ATGTTCTCAATAAAAAGAAAATGTTTCACT

refseq_ADARB1.F4 (forward primer)
refseq_ADARB1.R4 (reverse primer)
Single exon skipping

Frame 0

AAAAAAAAAAAKRPGWRPGLRAARGHGHAAPLR TTNEAERRPARDCGRSVGRACGGPGAARLRLRVE PFRLAWRA*GATEGDTLAKRGVLLTSVLLRYSL SPLAPKEAALGSEQT*S*KNFKMKLKWPMSTPS FIQRALRTP*RPGP*VMKIPRMKTPCQPDRNSLR QSRNPQKYFAMDIEDEENMSSSSTDVKENRNLD NVSPKDGSTPGPGEGSQLSNGGGGGPGRKRPLE EGSNGHSKYRLKKRRKTPGPVLPKNALMQLNEIK PGLQYTLLSQTGPVHAPLFVMSVEVNGQVFEGS GPTKKKAKLHAAEKALRSFVQFPNASEAHLAMG RTLSVNTDFTSDQADFPDTLFNGFETPDKAEPPF YVGSNGDDSFSSSGDLSLSASPVPASLAQPPLP VLPPFPPPSGKNPVMILNELRPGLKYDFLSESG ESHAKSFVMSVVVDGQFFEGSGRNKKLAKARAAQ SALAAIFNLHLDQTPSRQPIPSEGLQLHLPQVL ADAVSRLVLGKFGDLTDNFSSPHARRKVLAGVV MTTGTDVKDAKVISVSTGTKCINGEYMSDRGLAL NDCHAEIISRRSLLRFLYTQLELYLNNKDDQKR SIFQKSERGGFRLKENVQFHLYISTSPCGDARI FSPHEPILEEPADRHPNRKARGQLRTKIESGEGT IPVRSNASIQTWDGVLQGERLLTMSCSDKIARW NVVGIQGSLLSIFVEPIYFSSIILGSLYHGDHL SRAMYQRISNIEDLPPLYTLNKPLLSGISNAEAR QPGKAPNFSVNWTVGDSAIEVINATTGKDELGR ASRLCKHALYCRWMRVHGKVPSHLLRSKITKPN VYHESKLAAKEYQAAKARLFTAFIKAGLGAWVEK PTEQDQFSLTP*PGQT*WGVQGAVGIQRHPPEP HI*TGGRCIPWGGSRGTRGTTRCPRLSPASHIR PGAGAQCGEGMGCVRAQHRRLASLCRSISPSEPS SDCFQSRFTFRN*VLLSRASLSLGK*KLLCVKF LNK*FIQS*ECGL*NRK*LCQVTFMPHYFNCKK ASIYGGGWENRGRK**PKGNRHTSV*T*VSFLRR YLPG*FHTLGCNSLSLRSRLPAWCSVALSCTWG PAAVTVCPAEA*PRPL*PSASSRSFCTPCRIRS WKTFLSLLLSNHR*YMASNPRLAIHSGFLKDI*L LWTRRNHEGYCTIHGLSSLCSFL*IEWMWVTAR RPSQDGSRMISVDTHSWKMP*F*IIVSSFIKDM FEK*KASK*ELVRPRAAGVV*ARH*QS*RELRAA QRPACTGRPHDRGSQPGRSGARRARALCGPPPP SSEICTRCLVASAQDERGAERSALPASAVPSSK ALEGVQVH*GGDGSVFTLCTDLRMGLAKLWRLHI RTCPCLKTNTCTVALFPSQTLYPRSRWSAPGIK KENWPSFPPLNSVKL*TCSKDSFLSSPRCVSGK GIVFRVCPVYSVSAP*RVL*QSPWVRSGCTQPRG QWLLGAFRVSSSVHLMPGNRIRENSDLPGSRDW WRWMAGPTRP*LSCKGVSAFSVSCENPPVSGST VCTFLFTV*RDEYQATRTLLLATA*ADGM*GTDG PLNMN*TVKSTVYGTLMESAPKAVCFFRLWITC F*FDFRIWTLSMNVIRLRNMLLRCNPQCSLYVN LCIHHTLQLHELPLAQDQLELSMRRCQIQTKDLR CSQ*KENVS

Frame 1

RRRRRRRQRRPSGQVGGRGSGPREATATPRRCA QPTRQSAARRETAAEAWGARAEDQARRGCG*EW SLSGWHGELKGQLKETHWPSAEFCLLQSC*DTLS VRSHRRKLPWDQSRHKARKISR*N*NGQ*AHPH SSSEH*GPPRGQAHE**RSRG*RRLASQTETVS ASQETLKSILPWI*KMKKT*VPAALM*RKTAIWT TCPPRMAAHLGLARALSSPMGVVVAPAESGPWR RAAMATPSTA*RKGGKHQGPSSPRTP*CS*MRS SLVCSTHSCPRLGPCTRLCLSCLWR*MARFLRAL VPQRKRQNSMLLRRP*GLSFSFLMPLRPTWPWG GPCLSTRTSHLTRPTSLTRSSMVLKLLTRRSLP FTWAPMGMTPSVPAGTSACLLPRCLPA*PSLLSL SYHHSHPRVGRIP**S*TNCAQDSSMTSSPRAG RAMPRASSCLWSWMVSSLKARGETRSLPRPGLR SLPWPPFLTCTWIRRHLASLFPVRVFSCIYRRF* LTLSHAWSWVSLVT*PTTSPPLTLAEKCWLESS *QQAQMLKMPR**VFLQEQNVLMVNT*VIVALH *MTAMQK*YLGDPCSDFFIHNLSFT*ITKMIKKD PSFRNQSEGGLG*RRMSSFICTSAPLPVEMPES SHHMSQSWKNQQIDTQIVKQEDSYGPK*SLVRG RFQCAPMRASKRGTGCCKGSGCSPCPAVTRLHAG TWWASRDPCSAFSWSPFTSRASSWAAFTTGTTF PGPCTSGSPT*RTCHLSTPSTSLCSVASAMQKH GSQGRPPTSVSTGR*ATPLLRSSTPRLGRMSWAA RPACVSTRCTVAGCVCTARFPPTYYAPRLPSPT CTMSPSWRQRSTRPPRRVCSQPSSRRGWGPGWR SPPSRTSSHSRPDPGRHDGGCRGLWASSVILQNL TSELGAGAYLGEGVGGHGGPPGVHGCPQHLTSD LGQVRSVGRGWGASGPSIAAWHLSAAAFPLLNR PVTAFNLGLRLEIEFY*VGLP*V*ENRNYFV*NS *INNLFRARNVVYKIGSNCVRSLLCHIILIAKK HLYMEEGGKIEVGNSSLKEIATRLSKLRSLFSV GTSLGSSTH*VVTVSP*GADSQHGVAWPCHAHGV PQQ*LCVLQRRDPGPCSPQPPLEASVLLVGSDH GKLFSVYF*VITDNTWPVIPGWPFIQVF*RIFN FYGLEGITRATAQYMA*VPSVPSSESNGCG*PPE GLHRMEVE*FQ*ILILGKCHSFKLLFPALSKTC LKNKKHPSESW*DHVLLA*CRPDIDSPDGSSGL PSAQRARDGPTTEGVSPGGQERGGRGPCVDHLHQ AQRFAPGALLPPLRMKEELREVLCLPVQCPAPR L*RVFRYTEEGTAPSSHCAQI*GWD*RSCGDCT SGPAHVSKQTHVQWLFFLLKHFTPEAGGLPQA*R RKIGHLSHL*IL*NYRLAQKIPFYHPHAV*VER ALCSVCVQFTASLPPSVFCDNLPG*GVGAPSPE ASGCSGPSV*VLVFT*CRGIELEKTLTCRVPGTG GGGWQVRLDHDLVVRVCRLFQSHVKILLSLAAL SALSCLLFEGTSTKPQEHFFWPQHKLMVCKEPM GH*T*TERLKAQSMER*WSQPLKLFAFSGFGLHA FNLILESGHFL*M*FG*ETCC*DAILSVLCM*I CVYTTRYNCMSFLSHKTSWN*A*DAVKYRQRI* DVLNKKKMFH

Frame 2

GGGGGGGSGGQAARLAAGAPGRARPRPRRAAAH NQRGRAPPGARLRPKRGARVRRTRRGAAAAESG AFQAGMESLRGN*RRHTGQARSSAYFSPAEILS QSARTEGSCLGIRADIKLEKFQDEIEMANEHTLI HPASIEDPLEARPMSDEDPEDEDALPARQKQSP PVKKPSKVFCHGYRR*RKHEFQQH*CEGKPQSG QRVPQGWQHTWAWRGLSALQWGWWWPRQKAAPGG GQQWPLQVPPEEKEENTRARPPQERPDAAE*DQ AWFAVHTPVPDWARARAFVCHVCGGEWPGF*GL WSHKEKGKTPCC*EGLEVFRSVS*CL*GPPGHGE DPVCQHGLHI*PGRLP*HALQWF*NS*QGGASL LRGLQWG*LLQFQRGPQLVCFPGACQPSPASSP CLTTIPTPEWEESRDDLERTAPRTQV*LPLRERG EPCQELRHVCGRGWSVL*RLGEKQEACQGPGCA VCPGRHF*LALGSDAISPAYSQ*GSSAAFTAGF S*RCLTPGPG*VW*PDRQLLLPSRSQKSAGWSRH DNRHRC*RCQGDKCFYRNKMY*W*IHE*SWPCI K*LPCRNNISEILAQISLYTT*ALLK*QR*SKK IHLSEIRARGV*AEGECPVSSVHQHLSLWRCQNL LTT*ANPGRTSR*TPKS*SKRTATDQNRVW*GD DSSALQCEHPNVGRGAARGAAAHHVLQ*QDCTL ERGGHPGIPAQHFRGAHLLLEHHPGQPLPRGPPF QGHVPADLQHRGPATSLHPQQAFAQWHQQCRST AAREGPQLQCQLDGRRLRY*GHQRHDWEG*AGP RVPPV*ARVVLSLDACARQGSLPLTTLQDYQAQR VP*VQAGGKGVPGRQGASVHSLHQGGAGGLGGE AHRAGPVLTHALTRADMMGGAGGCGHPASSSRT SHLNWGQVHTLGRE*GDTGDHQVSTVVPSISHQT WGRCAVWGGDGVRQGPASPPGISLPQHFPF*TV Q*LLSISVYV*KLSSTE*GFLKFRKIEITLCEI LE*IIYSELGMWFIK*EVIVSGHFYATLF*LQKS IYIWRRVGK*R*EIVA*RKSPHVCLNLGLFSP* VPPWVVPHTRL*QSLPEEQTPSMV*RGPVMHMG SRSSDCVSCRGVTQAPVALSLL*KLLYSL*DQIM ENFSQFTSK*SQIIHGQ*SQAGHSFRFFKGYLT FMD*KESRGLLHNTWPKFPLFLPLNRMDVGDRP KAFTGWK*NDFSRYSFLENAIVLNYCFQLYQRHV *KIKSIQVRAGETTCCWRSVGQTLTVLTGAQGC PAPSVHGTAPRQRESAREVRSAAGEGPVWTTST KLRDLHQVPCCLRSG*KRS*EKCSACQCSAQLQG SRGCSGTLRRGRLRLHIVHRSEDGISEAVETAH PDLPMSQNKHMYSGSFSFSNTLPQKQVVCPRHK EGKLAIFPTSKFCKIIDLLKRFLFIIPTLCKWKG HCVPCVSSLQRLCPLACFVTISLGEEWVHPAPR PVVARGLPCEF*CSLDAGE*N*RKL*PAGFQGL VEVDGRSDSTMT*L*GCVGFFSLM*KSSCLWQHC LHFLVYCLKGRVPSHKNTSFGHSIS*WYVRNRW AIKHELNG*KHSLWNANGVSP*SCLLFQALDYM LLI*F*NLDTFYECNSAEKHVAEMQSSVFSVCKS VYTPHVTTA*ASSRTRPAGTEHETLSNTDKGFE MFSIKRKCFT