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Sequences

Sequence NM_139264

GCAGGCAGAGGAGCACTTAGCAGCTTATTCAGTGTCCGATTCTGATTCCGGCAAGGATCCAAGCATGGAATGCTGCCGTCGGGCAACTCCTGGCACACTG
CTCCTCTTTCTGGCTTTCCTGCTCCTGAGTTCCAGGACCGCACGCTCCGAGGAGGACCGGGACGGCCTATGGGATGCCTGGGGCCCATGGAGTGAATGCT
CACGCACCTGCGGGGGTGGGGCCTCCTACTCTCTGAGGCGCTGCCTGAGCAGCAAGAGCTGTGAAGGAAGAAATATCCGATACAGAACATGCAGTAATGT
GGACTGCCCACCAGAAGCAGGTGATTTCCGAGCTCAGCAATGCTCAGCTCATAATGATGTCAAGCACCATGGCCAGTTTTATGAATGGCTTCCTGTGTCT
AATGACCCTGACAACCCATGTTCACTCAAGTGCCAAGCCAAAGGAACAACCCTGGTTGTTGAACTAGCACCTAAGGTCTTAGATGGTACGCGTTGCTATA
CAGAATCTTTGGATATGTGCATCAGTGGTTTATGCCAAATTGTTGGCTGCGATCACCAGCTGGGAAGCACCGTCAAGGAAGATAACTGTGGGGTCTGCAA
CGGAGATGGGTCCACCTGCCGGCTGGTCCGAGGGCAGTATAAATCCCAGCTCTCCGCAACCAAATCGGATGATACTGTGGTTGCAATTCCCTATGGAAGT
AGACATATTCGCCTTGTCTTAAAAGGTCCTGATCACTTATATCTGGAAACCAAAACCCTCCAGGGGACTAAAGGTGAAAACAGTCTCAGCTCCACAGGAA
CTTTCCTTGTGGACAATTCTAGTGTGGACTTCCAGAAATTTCCAGACAAAGAGATACTGAGAATGGCTGGACCACTCACAGCAGATTTCATTGTCAAGAT
TCGTAACTCGGGCTCCGCTGACAGTACAGTCCAGTTCATCTTCTATCAACCCATCATCCACCGATGGAGGGAGACGGATTTCTTTCCTTGCTCAGCAACC
TGTGGAGGAGGTTATCAGCTGACATCGGCTGAGTGCTACGATCTGAGGAGCAACCGTGTGGTTGCTGACCAATACTGTCACTATTACCCAGAGAACATCA
AACCCAAACCCAAGCTTCAGGAGTGCAACTTGGATCCTTGTCCAGCCAGGTGGGAGGCCACCCCATGGACCGCGTGCTCCTCCTCGTGTGGGGGGGGCAT
CCAGAGCCGGGCAGTTTCCTGTGTGGAGGAGGACATCCAGGGGCATGTCACTTCAGTGGAAGAGTGGAAATGCATGTACACCCCTAAGATGCCCATCGCG
CAGCCCTGCAACATTTTTGACTGCCCTAAATGGCTGGCACAGGAGTGGTCTCCGGTAACTGTGCCTTCTTTCTTTGTTCATTAGGAGAGTAAGTCCACTC
TTCCCTCTCATCATCATGGCCCCACCGGGTACCCTGAGCAGCTCCACACTCTTCTTGAGGTGTCTAGAAGCCTACCAGCTTAGCTCCTGGAGTAGGAATG
CCCCAAATCCAGCATGACCAAAAGTAAATGATGTTTTTTTAAAGTGTCTTTCTTCAAGTTTCTTCAAGAAGCCTCTATTGTTCCCCAGATAATGTTCCCT
CAAATAGCACGGGGAAGCAACTGCCTTTCAAGGGTAATTGAGGCTGAATGAATGATCCCGAATCTGTAAAAGCTGCTTTGATGATAGAGCTCAGTAGACC
AGAAGTTTGATTTCATTTTGTATGTATTATGCTTTGTATCCGAAAGGGTCTAAGTGGATTAATATTAAAACTATGTATATTAATCATTGGAGAAGGGGGA
AGAGGAAATGAAAATAGCACAAAAATTAAAATTGGAACGAAGTAAGATAATTAAAACAAAAAACTTATAGATGTTAGGAAACCTGCTGTAATTAAACATA
AAATGTCATTCAGGGTTTCCTGACTGCTAATGCAGAAAGGAAAATCGTAAAGGAAACAGAAAGATGAAATAAGCCATTGTGCCCTCCGCCTCAGAAATGA
CAAAAGACTCTTCACTGAGCCCTGTGGCTTCATGGCAGCAGATCAGAGCTGTGACATTTTCTACATCTAGACATGCTACCAGACATGGGGAACCATTAGA
GGTGCAATCTACATTGGGCATCTGGTCATTCAATCTGTTTTTTTAAATGTTATTTTTGCCTTTCAATGTAATCAATTGGATTAACAATGCTGCAATATAA
TTTAGCTATAATCGTAGTTTAAATTTTTTGATATCCATGTAGGGGTATTTCCCATATTTTTGGAAGTAGCGGTCATTAGCAAAGTAACTAAATAAAATAC
AGTGCTGGTAGTCAAAATTAA
  • refseq_ADAMTSL1.F2 (forward primer)
  • refseq_ADAMTSL1.R2 (reverse primer)
  • Single exon skipping

Frame 0

AGRGALSSLFSVRF*FRQGSKHGMLPSGNSWHT
APLSGFPAPEFQDRTLRGGPGRPMGCLGPME*ML
THLRGWGLLLSEALPEQQEL*RKKYPIQNMQ*C
GLPTRSR*FPSSAMLSS**CQAPWPVL*MASCV
**P*QPMFTQVPSQRNNPGC*TST*GLRWYALLY
RIFGYVHQWFMPNCWLRSPAGKHRQGR*LWGLQ
RRWVHLPAGPRAV*IPALRNQIG*YCGCNSLWK
*TYSPCLKRS*SLISGNQNPPGD*R*KQSQLHRN
FPCGQF*CGLPEISRQRDTENGWTTHSRFHCQD
S*LGLR*QYSPVHLLSTHHPPMEGDGFLSLLSN
LWRRLSADIG*VLRSEEQPCGC*PILSLLPREHQ
TQTQASGVQLGSLSSQVGGHPMDRVLLLVWGGH
PEPGSFLCGGGHPGACHFSGRVEMHVHP*DAHR
AALQHF*LP*MAGTGVVSGNCAFFLCSLGE*VHS
SLSSSWPHRVP*AAPHSS*GV*KPTSLAPGVGM
PQIQHDQK*MMFF*SVFLQVSSRSLYCSPDNVP
SNSTGKQLPFKGN*G*MNDPESVKAALMIELSRP
EV*FHFVCIMLCIRKGLSGLILKLCILIIGEGG
RGNENSTKIKIGTK*DN*NKKLIDVRKPAVIKH
KMSFRVS*LLMQKGKS*RKQKDEISHCALRLRND
KRLFTEPCGFMAADQSCDIFYI*TCYQTWGTIR
GAIYIGHLVIQSVFLNVIFAFQCNQLD*QCCNI
I*L*S*FKFFDIHVGVFPIFLEVAVISKVTK*NT
VLVVKI

Frame 1

QAEEHLAAYSVSDSDSGKDPSMECCRRATPGTL
LLFLAFLLLSSRTARSEEDRDGLWDAWGPWSEC
SRTCGGGASYSLRRCLSSKSCEGRNIRYRTCSNV
DCPPEAGDFRAQQCSAHNDVKHHGQFYEWLPVS
NDPDNPCSLKCQAKGTTLVVELAPKVLDGTRCY
TESLDMCISGLCQIVGCDHQLGSTVKEDNCGVCN
GDGSTCRLVRGQYKSQLSATKSDDTVVAIPYGS
RHIRLVLKGPDHLYLETKTLQGTKGENSLSSTG
TFLVDNSSVDFQKFPDKEILRMAGPLTADFIVKI
RNSGSADSTVQFIFYQPIIHRWRETDFFPCSAT
CGGGYQLTSAECYDLRSNRVVADQYCHYYPENI
KPKPKLQECNLDPCPARWEATPWTACSSSCGGGI
QSRAVSCVEEDIQGHVTSVEEWKCMYTPKMPIA
QPCNIFDCPKWLAQEWSPVTVPSFFVH*ESKST
LPSHHHGPTGYPEQLHTLLEVSRSLPA*LLE*EC
PKSSMTKSK*CFFKVSFFKFLQEASIVPQIMFP
QIARGSNCLSRVIEAE*MIPNL*KLL***SSVD
QKFDFILYVLCFVSERV*VD*Y*NYVY*SLEKGE
EEMKIAQKLKLERSKIIKTKNL*MLGNLL*LNI
KCHSGFPDC*CRKENRKGNRKMK*AIVPSASEM
TKDSSLSPVASWQQIRAVTFSTSRHATRHGEPLE
VQSTLGIWSFNLFF*MLFLPFNVINWINNAAI*
FSYNRSLNFLISM*GYFPYFWK*RSLAK*LNKI
QCW*SKL

Frame 2

RQRST*QLIQCPILIPARIQAWNAAVGQLLAHC
SSFWLSCS*VPGPHAPRRTGTAYGMPGAHGVNA
HAPAGVGPPTL*GAA*AARAVKEEISDTEHAVM
WTAHQKQVISELSNAQLIMMSSTMASFMNGFLCL
MTLTTHVHSSAKPKEQPWLLN*HLRS*MVRVAI
QNLWICASVVYAKLLAAITSWEAPSRKITVGSA
TEMGPPAGWSEGSINPSSPQPNRMILWLQFPMEV
DIFALS*KVLITYIWKPKPSRGLKVKTVSAPQE
LSLWTILVWTSRNFQTKRY*EWLDHSQQISLSR
FVTRAPLTVQSSSSSINPSSTDGGRRISFLAQQP
VEEVIS*HRLSATI*GATVWLLTNTVTITQRTS
NPNPSFRSATWILVQPGGRPPHGPRAPPRVGGA
SRAGQFPVWRRTSRGMSLQWKSGNACTPLRCPSR
SPATFLTALNGWHRSGLR*LCLLSLFIRRVSPL
FPLIIMAPPGTLSSSTLFLRCLEAYQLSSWSRN
APNPA*PKVNDVFLKCLSSSFFKKPLLFPR*CSL
K*HGEATAFQG*LRLNE*SRICKSCFDDRAQ*T
RSLISFCMYYALYPKGSKWINIKTMYINHWRRG
KRK*K*HKN*NWNEVR*LKQKTYRC*ETCCN*T*
NVIQGFLTANAERKIVKETER*NKPLCPPPQK*
QKTLH*ALWLHGSRSEL*HFLHLDMLPDMGNH*
RCNLHWASGHSICFFKCYFCLSM*SIGLTMLQYN
LAIIVV*IF*YPCRGISHIFGSSGH*QSN*IKY
SAGSQN*

Sequence NM_052866

GCAGGCAGAGGAGCACTTAGCAGCTTATTCAGTGTCCGATTCTGATTCCGGCAAGGATCCAAGCATGGAATGCTGCCGTCGGGCAACTCCTGGCACACTG
CTCCTCTTTCTGGCTTTCCTGCTCCTGAGTTCCAGGACCGCACGCTCCGAGGAGGACCGGGACGGCCTATGGGATGCCTGGGGCCCATGGAGTGAATGCT
CACGCACCTGCGGGGGTGGGGCCTCCTACTCTCTGAGGCGCTGCCTGAGCAGCAAGAGCTGTGAAGGAAGAAATATCCGATACAGAACATGCAGTAATGT
GGACTGCCCACCAGAAGCAGGTGATTTCCGAGCTCAGCAATGCTCAGCTCATAATGATGTCAAGCACCATGGCCAGTTTTATGAATGGCTTCCTGTGTCT
AATGACCCTGACAACCCATGTTCACTCAAGTGCCAAGCCAAAGGAACAACCCTGGTTGTTGAACTAGCACCTAAGGTCTTAGATGGTACGCGTTGCTATA
CAGAATCTTTGGATATGTGCATCAGTGGTTTATGCCAAATTGTTGGCTGCGATCACCAGCTGGGAAGCACCGTCAAGGAAGATAACTGTGGGGTCTGCAA
CGGAGATGGGTCCACCTGCCGGCTGGTCCGAGGGCAGTATAAATCCCAGCTCTCCGCAACCAAATCGGATGATACTGTGGTTGCAATTCCCTATGGAAGT
AGACATATTCGCCTTGTCTTAAAAGGTCCTGATCACTTATATCTGGAAACCAAAACCCTCCAGGGGACTAAAGGTGAAAACAGTCTCAGCTCCACAGGAA
CTTTCCTTGTGGACAATTCTAGTGTGGACTTCCAGAAATTTCCAGACAAAGAGATACTGAGAATGGCTGGACCACTCACAGCAGATTTCATTGTCAAGAT
TCGTAACTCGGGCTCCGCTGACAGTACAGTCCAGTTCATCTTCTATCAACCCATCATCCACCGATGGAGGGAGACGGATTTCTTTCCTTGCTCAGCAACC
TGTGGAGGAGGTTATCAGCTGACATCGGCTGAGTGCTACGATCTGAGGAGCAACCGTGTGGTTGCTGACCAATACTGTCACTATTACCCAGAGAACATCA
AACCCAAACCCAAGCTTCAGGAGTGCAACTTGGATCCTTGTCCAGCCAGTGACGGATACAAGCAGATCATGCCTTATGACCTCTACCATCCCCTTCCTCG
GTGGGAGGCCACCCCATGGACCGCGTGCTCCTCCTCGTGTGGGGGGGGCATCCAGAGCCGGGCAGTTTCCTGTGTGGAGGAGGACATCCAGGGGCATGTC
ACTTCAGTGGAAGAGTGGAAATGCATGTACACCCCTAAGATGCCCATCGCGCAGCCCTGCAACATTTTTGACTGCCCTAAATGGCTGGCACAGGAGTGGT
CTCCGTGCACAGTGACATGTGGCCAGGGCCTCAGATACCGTGTGGTCCTCTGCATCGACCATCGAGGAATGCACACAGGAGGCTGTAGCCCAAAAACAAA
GCCCCACATAAAAGAGGAATGCATCGTACCCACTCCCTGCTATAAACCCAAAGAGAAACTTCCAGTCGAGGCCAAGTTGCCATGGTTCAAACAAGCTCAA
GAGCTAGAAGAAGGAGCTGCTGTGTCAGAGGAGCCCTCGTAAGTTGTAAAAGCACAGACTGTTCTATATTTGAAACTGTTTTGTTTAAAGAAAGCAGTGT
CTCACTGGTTGTAGCTTTCATGGGTTCTGAACTAAGTGTAATCATCTCACCAAAGCTTTTTGGCTCTCAAATTAAAGATTGATTAGTTTCAAAAA
  • refseq_ADAMTSL1.F2 (forward primer)
  • refseq_ADAMTSL1.R2 (reverse primer)
  • Single exon skipping

Frame 0

AGRGALSSLFSVRF*FRQGSKHGMLPSGNSWHT
APLSGFPAPEFQDRTLRGGPGRPMGCLGPME*ML
THLRGWGLLLSEALPEQQEL*RKKYPIQNMQ*C
GLPTRSR*FPSSAMLSS**CQAPWPVL*MASCV
**P*QPMFTQVPSQRNNPGC*TST*GLRWYALLY
RIFGYVHQWFMPNCWLRSPAGKHRQGR*LWGLQ
RRWVHLPAGPRAV*IPALRNQIG*YCGCNSLWK
*TYSPCLKRS*SLISGNQNPPGD*R*KQSQLHRN
FPCGQF*CGLPEISRQRDTENGWTTHSRFHCQD
S*LGLR*QYSPVHLLSTHHPPMEGDGFLSLLSN
LWRRLSADIG*VLRSEEQPCGC*PILSLLPREHQ
TQTQASGVQLGSLSSQ*RIQADHAL*PLPSPSS
VGGHPMDRVLLLVWGGHPEPGSFLCGGGHPGAC
HFSGRVEMHVHP*DAHRAALQHF*LP*MAGTGVV
SVHSDMWPGPQIPCGPLHRPSRNAHRRL*PKNK
APHKRGMHRTHSLL*TQRETSSRGQVAMVQTSS
RARRRSCCVRGALVSCKSTDCSIFETVLFKESSV
SLVVAFMGSELSVIISPKLFGSQIKD*LVSK

Frame 1

QAEEHLAAYSVSDSDSGKDPSMECCRRATPGTL
LLFLAFLLLSSRTARSEEDRDGLWDAWGPWSEC
SRTCGGGASYSLRRCLSSKSCEGRNIRYRTCSNV
DCPPEAGDFRAQQCSAHNDVKHHGQFYEWLPVS
NDPDNPCSLKCQAKGTTLVVELAPKVLDGTRCY
TESLDMCISGLCQIVGCDHQLGSTVKEDNCGVCN
GDGSTCRLVRGQYKSQLSATKSDDTVVAIPYGS
RHIRLVLKGPDHLYLETKTLQGTKGENSLSSTG
TFLVDNSSVDFQKFPDKEILRMAGPLTADFIVKI
RNSGSADSTVQFIFYQPIIHRWRETDFFPCSAT
CGGGYQLTSAECYDLRSNRVVADQYCHYYPENI
KPKPKLQECNLDPCPASDGYKQIMPYDLYHPLPR
WEATPWTACSSSCGGGIQSRAVSCVEEDIQGHV
TSVEEWKCMYTPKMPIAQPCNIFDCPKWLAQEW
SPCTVTCGQGLRYRVVLCIDHRGMHTGGCSPKTK
PHIKEECIVPTPCYKPKEKLPVEAKLPWFKQAQ
ELEEGAAVSEEPS*VVKAQTVLYLKLFCLKKAV
SHWL*LSWVLN*V*SSHQSFLALKLKID*FQK

Frame 2

RQRST*QLIQCPILIPARIQAWNAAVGQLLAHC
SSFWLSCS*VPGPHAPRRTGTAYGMPGAHGVNA
HAPAGVGPPTL*GAA*AARAVKEEISDTEHAVM
WTAHQKQVISELSNAQLIMMSSTMASFMNGFLCL
MTLTTHVHSSAKPKEQPWLLN*HLRS*MVRVAI
QNLWICASVVYAKLLAAITSWEAPSRKITVGSA
TEMGPPAGWSEGSINPSSPQPNRMILWLQFPMEV
DIFALS*KVLITYIWKPKPSRGLKVKTVSAPQE
LSLWTILVWTSRNFQTKRY*EWLDHSQQISLSR
FVTRAPLTVQSSSSSINPSSTDGGRRISFLAQQP
VEEVIS*HRLSATI*GATVWLLTNTVTITQRTS
NPNPSFRSATWILVQPVTDTSRSCLMTSTIPFL
GGRPPHGPRAPPRVGGASRAGQFPVWRRTSRGMS
LQWKSGNACTPLRCPSRSPATFLTALNGWHRSG
LRAQ*HVARASDTVWSSASTIEECTQEAVAQKQ
SPT*KRNASYPLPAINPKRNFQSRPSCHGSNKLK
S*KKELLCQRSPRKL*KHRLFYI*NCFV*RKQC
LTGCSFHGF*TKCNHLTKAFWLSN*RLISFK

Sequence NM_139238

GCAGGCAGAGGAGCACTTAGCAGCTTATTCAGTGTCCGATTCTGATTCCGGCAAGGATCCAAGCATGGAATGCTGCCGTCGGGCAACTCCTGGCACACTG
CTCCTCTTTCTGGCTTTCCTGCTCCTGAGTTCCAGGACCGCACGCTCCGAGGAGGACCGGGACGGCCTATGGGATGCCTGGGGCCCATGGAGTGAATGCT
CACGCACCTGCGGGGGTGGGGCCTCCTACTCTCTGAGGCGCTGCCTGAGCAGCAAGAGCTGTGAAGGAAGAAATATCCGATACAGAACATGCAGTAATGT
GGACTGCCCACCAGAAGCAGGTGATTTCCGAGCTCAGCAATGCTCAGCTCATAATGATGTCAAGCACCATGGCCAGTTTTATGAATGGCTTCCTGTGTCT
AATGACCCTGACAACCCATGTTCACTCAAGTGCCAAGCCAAAGGAACAACCCTGGTTGTTGAACTAGCACCTAAGGTCTTAGATGGTACGCGTTGCTATA
CAGAATCTTTGGATATGTGCATCAGTGGTTTATGCCAAATTGTTGGCTGCGATCACCAGCTGGGAAGCACCGTCAAGGAAGATAACTGTGGGGTCTGCAA
CGGAGATGGGTCCACCTGCCGGCTGGTCCGAGGGCAGTATAAATCCCAGCTCTCCGCAACCAAATCGGATGATACTGTGGTTGCAATTCCCTATGGAAGT
AGACATATTCGCCTTGTCTTAAAAGGTCCTGATCACTTATATCTGGAAACCAAAACCCTCCAGGGGACTAAAGGTGAAAACAGTCTCAGCTCCACAGGAA
CTTTCCTTGTGGACAATTCTAGTGTGGACTTCCAGAAATTTCCAGACAAAGAGATACTGAGAATGGCTGGACCACTCACAGCAGATTTCATTGTCAAGAT
TCGTAACTCGGGCTCCGCTGACAGTACAGTCCAGTTCATCTTCTATCAACCCATCATCCACCGATGGAGGGAGACGGATTTCTTTCCTTGCTCAGCAACC
TGTGGAGGAGGTTATCAGCTGACATCGGCTGAGTGCTACGATCTGAGGAGCAACCGTGTGGTTGCTGACCAATACTGTCACTATTACCCAGAGAACATCA
AACCCAAACCCAAGCTTCAGGAGTGCAACTTGGATCCTTGTCCAGCCAGTGACGGATACAAGCAGATCATGCCTTATGACCTCTACCATCCCCTTCCTCG
GTGGGAGGCCACCCCATGGACCGCGTGCTCCTCCTCGTGTGGGGGGGGCATCCAGAGCCGGGCAGTTTCCTGTGTGGAGGAGGACATCCAGGGGCATGTC
ACTTCAGTGGAAGAGTGGAAATGCATGTACACCCCTAAGATGCCCATCGCGCAGCCCTGCAACATTTTTGACTGCCCTAAATGGCTGGCACAGGAGTGGT
CTCCGTGCACAGTGACATGTGGCCAGGGCCTCAGATACCGTGTGGTCCTCTGCATCGACCATCGAGGAATGCACACAGGAGGCTGTAGCCCAAAAACAAA
GCCCCACATAAAAGAGGAATGCATCGTACCCACTCCCTGCTATAAACCCAAAGAGAAACTTCCAGTCGAGGCCAAGTTGCCATGGTTCAAACAAGCTCAA
GAGCTAGAAGAAGGAGCTGCTGTGTCAGAGGAGCCCTCGTTCATCCCAGAGGCCTGGTCGGCCTGCACAGTCACCTGTGGTGTGGGGACCCAGGTGCGAA
TAGTCAGGTGCCAGGTGCTCCTGTCTTTCTCTCAGTCCGTGGCTGACCTGCCTATTGACGAGTGTGAAGGGCCCAAGCCAGCATCCCAGCGTGCCTGTTA
TGCAGGCCCATGCAGCGGGGAAATTCCTGAGTTCAACCCAGACGAGACAGATGGGCTCTTTGGTGGCCTGCAGGATTTCGACGAGCTGTATGACTGGGAG
TATGAGGGGTTCACCAAGTGCTCCGAGTCCTGTGGAGGAGGTGTCCAGGAGGCTGTGGTGAGCTGCTTGAACAAACAGACTCGGGAGCCTGCTGAGGAGA
ACCTGTGCGTGACCAGCCGCCGGCCCCCACAGCTCCTGAAGTCCTGCAATTTGGATCCCTGCCCAGCAAGAAGCAGTATCGACTCAGCATGGAACGCCTG
CAACGTTCTTTGTTAGGCAACCAAGAGGCCTGGCTTCTCATCCTGCTGTCACCAACTAGCTCTGTGGCCTAGGGCGAGGTGTCTGCCCTTTATGTTTCCA
CATCTGCAAAGTGAACTGGTTGTACCTGATGATCTGAGATCCCATGACTTGCTCACATGTCCCATGATTCTTTATTTTGTAGGCAGAAGCATTAAACAGC
TACTCCTGCTGCTGTGT
  • refseq_ADAMTSL1.F2 (forward primer)
  • refseq_ADAMTSL1.R2 (reverse primer)
  • Single exon skipping

Frame 0

AGRGALSSLFSVRF*FRQGSKHGMLPSGNSWHT
APLSGFPAPEFQDRTLRGGPGRPMGCLGPME*ML
THLRGWGLLLSEALPEQQEL*RKKYPIQNMQ*C
GLPTRSR*FPSSAMLSS**CQAPWPVL*MASCV
**P*QPMFTQVPSQRNNPGC*TST*GLRWYALLY
RIFGYVHQWFMPNCWLRSPAGKHRQGR*LWGLQ
RRWVHLPAGPRAV*IPALRNQIG*YCGCNSLWK
*TYSPCLKRS*SLISGNQNPPGD*R*KQSQLHRN
FPCGQF*CGLPEISRQRDTENGWTTHSRFHCQD
S*LGLR*QYSPVHLLSTHHPPMEGDGFLSLLSN
LWRRLSADIG*VLRSEEQPCGC*PILSLLPREHQ
TQTQASGVQLGSLSSQ*RIQADHAL*PLPSPSS
VGGHPMDRVLLLVWGGHPEPGSFLCGGGHPGAC
HFSGRVEMHVHP*DAHRAALQHF*LP*MAGTGVV
SVHSDMWPGPQIPCGPLHRPSRNAHRRL*PKNK
APHKRGMHRTHSLL*TQRETSSRGQVAMVQTSS
RARRRSCCVRGALVHPRGLVGLHSHLWCGDPGAN
SQVPGAPVFLSVRG*PAY*RV*RAQASIPACLL
CRPMQRGNS*VQPRRDRWALWWPAGFRRAV*LG
V*GVHQVLRVLWRRCPGGCGELLEQTDSGAC*GE
PVRDQPPAPTAPEVLQFGSLPSKKQYRLSMERL
QRSLLGNQEAWLLILLSPTSSVA*GEVSALYVS
TSAK*TGCT**SEIP*LAHMSHDSLFCRQKH*TA
TPAAV

Frame 1

QAEEHLAAYSVSDSDSGKDPSMECCRRATPGTL
LLFLAFLLLSSRTARSEEDRDGLWDAWGPWSEC
SRTCGGGASYSLRRCLSSKSCEGRNIRYRTCSNV
DCPPEAGDFRAQQCSAHNDVKHHGQFYEWLPVS
NDPDNPCSLKCQAKGTTLVVELAPKVLDGTRCY
TESLDMCISGLCQIVGCDHQLGSTVKEDNCGVCN
GDGSTCRLVRGQYKSQLSATKSDDTVVAIPYGS
RHIRLVLKGPDHLYLETKTLQGTKGENSLSSTG
TFLVDNSSVDFQKFPDKEILRMAGPLTADFIVKI
RNSGSADSTVQFIFYQPIIHRWRETDFFPCSAT
CGGGYQLTSAECYDLRSNRVVADQYCHYYPENI
KPKPKLQECNLDPCPASDGYKQIMPYDLYHPLPR
WEATPWTACSSSCGGGIQSRAVSCVEEDIQGHV
TSVEEWKCMYTPKMPIAQPCNIFDCPKWLAQEW
SPCTVTCGQGLRYRVVLCIDHRGMHTGGCSPKTK
PHIKEECIVPTPCYKPKEKLPVEAKLPWFKQAQ
ELEEGAAVSEEPSFIPEAWSACTVTCGVGTQVR
IVRCQVLLSFSQSVADLPIDECEGPKPASQRACY
AGPCSGEIPEFNPDETDGLFGGLQDFDELYDWE
YEGFTKCSESCGGGVQEAVVSCLNKQTREPAEE
NLCVTSRRPPQLLKSCNLDPCPARSSIDSAWNAC
NVLC*ATKRPGFSSCCHQLALWPRARCLPFMFP
HLQSELVVPDDLRSHDLLTCPMILYFVGRSIKQ
LLLLLC

Frame 2

RQRST*QLIQCPILIPARIQAWNAAVGQLLAHC
SSFWLSCS*VPGPHAPRRTGTAYGMPGAHGVNA
HAPAGVGPPTL*GAA*AARAVKEEISDTEHAVM
WTAHQKQVISELSNAQLIMMSSTMASFMNGFLCL
MTLTTHVHSSAKPKEQPWLLN*HLRS*MVRVAI
QNLWICASVVYAKLLAAITSWEAPSRKITVGSA
TEMGPPAGWSEGSINPSSPQPNRMILWLQFPMEV
DIFALS*KVLITYIWKPKPSRGLKVKTVSAPQE
LSLWTILVWTSRNFQTKRY*EWLDHSQQISLSR
FVTRAPLTVQSSSSSINPSSTDGGRRISFLAQQP
VEEVIS*HRLSATI*GATVWLLTNTVTITQRTS
NPNPSFRSATWILVQPVTDTSRSCLMTSTIPFL
GGRPPHGPRAPPRVGGASRAGQFPVWRRTSRGMS
LQWKSGNACTPLRCPSRSPATFLTALNGWHRSG
LRAQ*HVARASDTVWSSASTIEECTQEAVAQKQ
SPT*KRNASYPLPAINPKRNFQSRPSCHGSNKLK
S*KKELLCQRSPRSSQRPGRPAQSPVVWGPRCE
*SGARCSCLSLSPWLTCLLTSVKGPSQHPSVPV
MQAHAAGKFLSSTQTRQMGSLVACRISTSCMTGS
MRGSPSAPSPVEEVSRRLW*AA*TNRLGSLLRR
TCA*PAAGPHSS*SPAIWIPAQQEAVSTQHGTP
ATFFVRQPRGLASHPAVTN*LCGLGRGVCPLCFH
ICKVNWLYLMI*DPMTCSHVP*FFIL*AEALNS
YSCCC

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