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Sequences

Sequence NM_001282

GTCAGAGTTTCCTGCCCACCATCTTTGTCCCTGGCAAAGTGGGTTTTGCGCAGTGGCTTAGACCTAGAAAAGAATCGTGACGGGCAGGAAACCATTACAC
CACCACCTGGGCTGTGCTCTCCGGCTCCCGCCGCCACCCCCGCCCTCGCCTTCGCCTCCGCCTCCGGTGCACATTAAAGATCCAAAGTCATGACTGACTC
CAAGTATTTCACAACCAATAAAAAAGGAGAAATATTTGAACTAAAAGCTGAACTCAACAATGAAAAGAAAGAAAAGAGAAAGGAGGCTGTGAAGAAAGTG
ATTGCTGCTATGACCGTGGGGAAGGATGTTAGTTCTCTCTTTCCAGACGTAGTGAACTGTATGCAGACTGACAATCTGGAACTAAAGAAGCTTGTGTATC
TCTACTTGATGAACTACGCCAAGAGTCAGCCAGACATGGCCATCATGGCTGTAAACAGCTTTGTGAAGGACTGTGAAGATCCTAATCCTTTGATTCGAGC
CTTGGCAGTCAGAACCATGGGGTGCATCCGGGTAGACAAAATTACAGAATATCTCTGTGAGCCGCTCCGCAAGTGCTTGAAGGATGAGGATCCCTATGTT
CGGAAAACAGCAGCAGTCTGCGTGGCAAAACTCCATGATATCAATGCCCAAATGGTGGAAGATCAGGGATTTCTGGATTCTCTACGGGATCTCATAGCAG
ATTCAAATCCAATGGTGGTGGCTAATGCCGTAGCGGCATTATCTGAAATCAGTGAGTCTCACCCAAACAGCAACTTACTTGATCTGAACCCACAGAACAT
TAATAAGCTGCTGACAGCCCTGAATGAATGCACTGAATGGGGCCAGATTTTCATCCTGGACTGCCTGTCTAATTACAACCCTAAAGATGATCGGGAGGCT
CAGAGCATCTGTGAGCGGGTAACTCCCCGGCTATCCCATGCCAACTCAGCAGTGGTGCTTTCAGCGGTAAAAGTCCTAATGAAGTTTCTAGAATTGTTAC
CTAAGGATTCTGACTACTACAATATGCTGCTGAAGAAGTTAGCCCCTCCACTTGTCACTTTGCTGTCTGGGGAGCCAGAAGTGCAGTATGTCGCCCTGAG
GAACATCAACTTAATTGTCCAGAAAAGGCCTGAAATCTTGAAGCAGGAAATCAAAGTCTTCTTTGTGAAGTACAATGATCCCATCTATGTTAAACTAGAG
AAGTTGGACATCATGATTCGTTTGGCATCTCAAGCCAACATTGCTCAGGTTCTGGCAGAACTGAAAGAATATGCTACAGAGGTGGATGTTGACTTTGTTC
GAAAAGCTGTGCGGGCCATTGGACGGTGTGCCATCAAGGTGGAGCAATCTGCAGAGCGCTGTGTAAGCACATTGCTTGATCTAATCCAGACCAAAGTGAA
TTATGTGGTCCAAGAAGCAATTGTTGTCATCAGGGACATCTTCCGCAAATACCCCAACAAGTATGAAAGTATCATCGCCACTCTGTGTGAGAACTTAGAC
TCGCTGGATGAGCCAGATGCTCGAGCAGCTATGATTTGGATTGTGGGAGAATATGCTGAAAGAATTGACAATGCAGATGAGTTACTAGAAAGCTTCCTGG
AGGGTTTTCACGATGAAAGCACCCAGGTGCAGCTCACTCTGCTTACTGCCATAGTGAAGCTGTTTCTCAAGAAACCATCAGAAACACAGGAGCTAGTCCA
GCAGGTCTTGAGTTTGGCAACACAGGATTCTGATAATCCTGACCTTCGAGACCGGGGCTATATTTATTGGCGCCTTCTCTCAACTGACCCTGTTACAGCT
AAAGAAGTAGTCTTGTCTGAGAAGCCACTGATCTCTGAGGAGACGGACCTTATTGAGCCAACTCTGCTGGATGAGCTAATCTGCCACATTGGTTCTTTGG
CCTCTGTGTATCATAAGCCTCCCAATGCTTTTGTGGAAGGAAGTCATGGAATTCATCGTAAACACTTGCCAATTCATCATGGGAGCACTGATGCAGGTGA
CAGCCCTGTTGGCACTACCACTGCAACGAACCTGGAACAGCCTCAGGTTATCCCCTCTCAAGGTGATCTTCTAGGGGATCTTTTAAACCTTGACCTCGGT
CCCCCAGTCAATGTGCCACAGGTGTCCTCCATGCAGATGGGAGCAGTGGATCTCCTAGGAGGAGGACTAGATAGTCTGGTGGGACAATCCTTCATCCCAT
CA
TCGGTGCCTGCAACCTTTGCTCCTTCACCTACACCTGCTGTGGTCAGCAGTGGACTGAATGACCTGTTTGAACTCTCCACAGGGATAGGCATGGCACC
TGGTGGATATGTGGCTCCTAAGGCTGTCTGGCTACCTGCAGTAAAGGCTAAAGGCTTGGAGATTTCCGGAACATTTACTCACCGCCAAGGGCACATCTAT
ATGGAAATGAACTTCACCAATAAAGCTCTGCAGCACATGACAGATTTTGCAATCCAGTTTAACAAAAATAGCTTTGGTGTCATCCCCAGCACTCCTCTGG
CCATCCATACACCACTGATGCCAAACCAGAGCATTGATGTCTCCCTGCCTCTCAATACCTTGGGCCCAGTCATGAAGATGGAACCTCTGAATAACCTCCA
GGTGGCTGTGAAAAACAATATCGATGTCTTCTACTTCAGCTGCCTCATCCCACTCAATGTGCTTTTTGTAGAAGATGGCAAAATGGAGCGCCAGGTCTTC
CTTGCAACATGGAAGGATATTCCCAATGAAAATGAACTTCAGTTTCAGATTAAGGAATGTCATTTAAATGCTGACACTGTTTCCAGCAAGTTGCAAAACA
ACAATGTTTATACTATTGCCAAGAGGAATGTGGAAGGGCAGGACATGCTGTACCAATCCCTGAAGCTCACTAATGGCATTTGGATTTTGGCCGAACTACG
TATCCAGCCAGGAAACCCCAATTACACGCTGTCACTGAAGTGTAGAGCTCCTGAAGTCTCTCAATACATCTATCAGGTCTACGACAGCATTTTGAAAAAC
TAACAAGACTGGTCCAGTACCCTTCAACCATGCTGTGATCGGTGCAAGTCAAGAACTCTTAACTGGAAGAAATTGTATTGCTGCGTAGAATCTGAACACA
CTGAGGCCACCTAGCAAGGTAGTAACTAGTCTAACCTGTGCTAACATTAGGGCACAACCTGTTGGATAGTTTTAGCTTCCTGTGAACATTTGTAACCACT
GCTTCAGTCACCTCCCACCTCTTGCCACCTGCTGCTGCTATCTGTCCTTACTTGTGGGCTTCTCCATGCTGTGCCAATGGCTGGCTTTTTCTACACCCTC
TTTTGAGTGTAGTTTGGTATTTTGTAATTGAGAGCTCATTTCAAAAGCAGAAAAAGACAACAAATATTAAAGCAAGGAAAAGTGTAACTGAAACACTGCA
CTTTACTGTTTTATACTTTTGTACATATGAGAAATCAAGGGATTAGTGCAACCAGTAGAAAGCATTGAAATGACTGTCATTAACCACACAGTCCTGGAGG
CAGAGATGCAGTTACCTACCCTAGCTTTTGATGGGTTCTCTTACCTGTAGTAGCCTTATCCCTGGTCATTTGGATTTTCAGTTTGCTTTTTTCTTTTTTT
CCCCTCCAAACTCCTTTTCCTTGGCCAAGCCTTCATGCTTCCCCCTTTCCATATTATAATCTCATTTGATTGCTCTGCAGTTGGGAACGGTGATCTTCTT
GAATGATGTTTCAGTGTGCAAAAACTATAGAGCCTGTCAGCACCAAAGCTGACAGAAGTTATACCTTACTCCTTTCCTTTCCCCTGAACAAACCTGCTAA
TCCCACTAATTCAGGAATTTGAGTAGAGATGGGGAACAAGAACCCAGATGCTGTCCCCTCACCCCCTCTCCTGTATTTCTCAGGTCCAGTTCAAATCTAA
AATTCTACTTTTAGAGTTGAAACAGAGTAATAACTTATCTAACCCTCTTTTCCTACAAAGGAGAAAGATAAAAGGCACAAAGGTTACCGCCAAGGCCCGT
CAGCTGTGTAGTGGCAAAGCCGAGACCGAGTCTCCTAAGTCCCCGTCAGTGTGGTTTTCACCACAGGACTGTCTCTTGTCGTTTTCCCCTAATGCCTTCT
CCTGCCTTTTCTGTGCCTAGTTTTTGGCTCTTCACATATTCCATATTGATTTTGACGCTCTGTATATTGGCATCAGGTGGCAGCTGAATATCTTTTGAAT
TACTCGAAGGTAAAGCCAGATGCCAGAATGAAGGTGTAGCCAGTGTTTCCCATATGCCCCTGGAGCCCCACTTATTGAGGCCAGCAGAATAGGTGCAGAG
ATGAAGTGAGCTTAGAGATGTTGCAAATGCTCTTTATCCCTTCAGCTCTCTGATCTGCTCTTTCTTCATGATACTTAGTCTGCAGGGCATATTAAGATCA
TCCCAGAGGTTCAGGCAGTTCCTGTCATCTCTGAAAAGACTGGGGGATATGAAATCTTCCCCCTACCCCACTTAATGCGTTGGATATGATTTTTCAAAGA
ATGCTTCATGCCCAAAATACCAGCCTGTTTAGCAGTGTTACACTGTTTGATCTGCGGGCACTTGTTGCATTGCCTGGCACCCAATATTCAGGGTCCATGA
CTAAGACTGGTCTTCTCAGATGCCCTGCTTAAATCAGGGGCACTTCAGGCTCCACAGGCGTCATGTTGGACTGAGACCTAACTCACTGGACTCAGAGGAG
GAATCGTGGAAAACAAGAGCAAAACTACCCCACACCCCTATTTCATGTCTGAAATAACCCTGTTTCATACCAGTTGCAAAGCTTGTGGGGAGCGGTCCCA
CAAAGCACTTTCTTAAACCTTGAGAATCTCCAAGAGAAAAATATTTGGGGAAGGAGGGAGGAAATATGTCCCTTGCACACCACCCCTGAAGCACATGGCA
GTAGGAAACAGCATAGGATTGTATGTGGGAGGTGGATAGGTCGGTGATGTGTGGAGCGGAAAAGCAGGTTGGTAAAGTTCCCTTCTTGGGACTTATTCCT
GGAGTCAGTGGATACAAGTAGTGCAGAAGGTTCACACTGCAAATAGTGTTCTCATCTCAAAGCAAACTATCATTCCAGAAGGAAAAGTGTGTCAGGGCAA
GCAGACAACACAATTTCCTATCAGAATATGTCCCTCAACCCCCGAAACAAGGCTTCTCTCAGCCTCCCCACCAGTGATGGATAACAGCTCCTATTCTCAG
CTGACCTGACTGAGCCAACCCATGAACTCTTCACTCCTTGGGGAAGCCACCTCCCATCACACCCCTGAGCAGAGTTAGGGAGGAATTCTACTTCCCATAA
AAGGACCTCTCCTGAGAGGCAAAACCTGTTGCCTCCACCACGGCTTCCCTCTTGGCTCATTCCAAGCTTGGCCAAATTGGGGAAGTGGGATGGAGGTTGC
CCTGCATCCCCCCTCCTCTGCCTGAGTGTGTCTTTGTAATGTCAGCTGGCATCATACAAAGAGCAGGAGAAGCAAACACCCAGAACTCTTTTGCTGGTCA
GAGATTCCCTGAGTGTCTGTCCTCACCCAAGCCTGCTCTGTGTCTGTGTTGTGAAGCTTGAGACTCTGGAAAGAAATGGGGAGGGGGGGCAGGGGAAATG
TTGCCCTAAGAATGCTTCTCATTCCTCTGTTCTTATTGGGTCCTGTTTTTCGGGAGGGTGGGGGTTGGGGGAAGCTTGACCTTGTGTCTTCGTCAATAAA
CTCACATTTACACAAAATGAA
  • refseq_AP2B1.F1 (forward primer)
  • refseq_AP2B1.R1 (reverse primer)
  • Single exon skipping

Frame 0

VRVSCPPSLSLAKWVLRSGLDLEKNRDGQETIT
PPPGLCSPAPAATPALAFASASGAH*RSKVMTDS
KYFTTNKKGEIFELKAELNNEKKEKRKEAVKKV
IAAMTVGKDVSSLFPDVVNCMQTDNLELKKLVY
LYLMNYAKSQPDMAIMAVNSFVKDCEDPNPLIRA
LAVRTMGCIRVDKITEYLCEPLRKCLKDEDPYV
RKTAAVCVAKLHDINAQMVEDQGFLDSLRDLIA
DSNPMVVANAVAALSEISESHPNSNLLDLNPQNI
NKLLTALNECTEWGQIFILDCLSNYNPKDDREA
QSICERVTPRLSHANSAVVLSAVKVLMKFLELL
PKDSDYYNMLLKKLAPPLVTLLSGEPEVQYVALR
NINLIVQKRPEILKQEIKVFFVKYNDPIYVKLE
KLDIMIRLASQANIAQVLAELKEYATEVDVDFV
RKAVRAIGRCAIKVEQSAERCVSTLLDLIQTKVN
YVVQEAIVVIRDIFRKYPNKYESIIATLCENLD
SLDEPDARAAMIWIVGEYAERIDNADELLESFL
EGFHDESTQVQLTLLTAIVKLFLKKPSETQELVQ
QVLSLATQDSDNPDLRDRGYIYWRLLSTDPVTA
KEVVLSEKPLISEETDLIEPTLLDELICHIGSL
ASVYHKPPNAFVEGSHGIHRKHLPIHHGSTDAGD
SPVGTTTATNLEQPQVIPSQGDLLGDLLNLDLG
PPVNVPQVSSMQMGAVDLLGGGLDSLVGQSFIP
S
SVPATFAPSPTPAVVSSGLNDLFELSTGIGMAP
GGYVAPKAVWLPAVKAKGLEISGTFTHRQGHIY
MEMNFTNKALQHMTDFAIQFNKNSFGVIPSTPL
AIHTPLMPNQSIDVSLPLNTLGPVMKMEPLNNLQ
VAVKNNIDVFYFSCLIPLNVLFVEDGKMERQVF
LATWKDIPNENELQFQIKECHLNADTVSSKLQN
NNVYTIAKRNVEGQDMLYQSLKLTNGIWILAELR
IQPGNPNYTLSLKCRAPEVSQYIYQVYDSILKN
*QDWSSTLQPCCDRCKSRTLNWKKLYCCVESEH
TEAT*QGSN*SNLC*H*GTTCWIVLASCEHL*PL
LQSPPTSCHLLLLSVLTCGLLHAVPMAGFFYTL
F*V*FGIL*LRAHFKSRKRQQILKQGKV*LKHC
TLLFYTFVHMRNQGISATSRKH*NDCH*PHSPGG
RDAVTYPSF*WVLLPVVALSLVIWIFSLLFSFF
PLQTPFPWPSLHASPFPYYNLI*LLCSWER*SS
*MMFQCAKTIEPVSTKADRSYTLLLSFPLNKPAN
PTNSGI*VEMGNKNPDAVPSPPLLYFSGPVQI*
NSTFRVETE**LI*PSFPTKEKDKRHKGYRQGP
SAV*WQSRDRVS*VPVSVVFTTGLSLVVFP*CLL
LPFLCLVFGSSHIPY*F*RSVYWHQVAAEYLLN
YSKVKPDARMKV*PVFPICPWSPTY*GQQNRCR
DEVSLEMLQMLFIPSAL*SALSS*YLVCRAY*DH
PRGSGSSCHL*KDWGI*NLPPTPLNALDMIFQR
MLHAQNTSLFSSVTLFDLRALVALPGTQYSGSM
TKTGLLRCPA*IRGTSGSTGVMLD*DLTHWTQRR
NRGKQEQNYPTPLFHV*NNPVSYQLQSLWGAVP
QSTFLNLENLQEKNIWGRREEICPLHTTPEAHG
SRKQHRIVCGRWIGR*CVERKSRLVKFPSWDLFL
ESVDTSSAEGSHCK*CSHLKANYHSRRKSVSGQ
ADNTISYQNMSLNPRNKASLSLPTSDG*QLLFS
ADLTEPTHELFTPWGSHLPSHP*AELGRNSTSHK
RTSPERQNLLPPPRLPSWLIPSLAKLGKWDGGC
PASPLLCLSVSL*CQLASYKEQEKQTPRTLLLV
RDSLSVCPHPSLLCVCVVKLETLERNGEGGQGKC
CPKNASHSSVLIGSCFSGGWGLGEA*PCVFVNK
LTFTQNE

Frame 1

SEFPAHHLCPWQSGFCAVA*T*KRIVTGRKPLH
HHLGCALRLPPPPPPSPSPPPPVHIKDPKS*LT
PSISQPIKKEKYLN*KLNSTMKRKKRERRL*RK*
LLL*PWGRMLVLSFQT**TVCRLTIWN*RSLCI
ST**TTPRVSQTWPSWL*TAL*RTVKILIL*FE
PWQSEPWGASG*TKLQNISVSRSASA*RMRIPMF
GKQQQSAWQNSMISMPKWWKIRDFWILYGIS*Q
IQIQWWWLMP*RHYLKSVSLTQTATYLI*THRT
LISC*QP*MNALNGARFSSWTACLITTLKMIGRL
RASVSG*LPGYPMPTQQWCFQR*KS**SF*NCY
LRILTTTICC*RS*PLHLSLCCLGSQKCSMSP*
GTST*LSRKGLKS*SRKSKSSL*STMIPSMLN*R
SWTS*FVWHLKPTLLRFWQN*KNMLQRWMLTLF
EKLCGPLDGVPSRWSNLQSAV*AHCLI*SRPK*
IMWSKKQLLSSGTSSANTPTSMKVSSPLCVRT*T
RWMSQMLEQL*FGLWENMLKELTMQMSY*KASW
RVFTMKAPRCSSLCLLP**SCFSRNHQKHRS*S
SRS*VWQHRILIILTFETGAIFIGAFSQLTLLQL
KK*SCLRSH*SLRRRTLLSQLCWMS*SATLVLW
PLCIISLPMLLWKEVMEFIVNTCQFIMGALMQV
TALLALPLQRTWNSLRLSPLKVIF*GIF*TLTSV
PQSMCHRCPPCRWEQWIS*EED*IVWWDNPSSH
H
RCLQPLLLHLHLLWSAVD*MTCLNSPQG*AWH
LVDMWLLRLSGYLQ*RLKAWRFPEHLLTAKGTSI
WK*TSPIKLCST*QILQSSLTKIALVSSPALLW
PSIHH*CQTRALMSPCLSIPWAQS*RWNL*ITS
RWL*KTISMSSTSAASSHSMCFL*KMAKWSARSS
LQHGRIFPMKMNFSFRLRNVI*MLTLFPASCKT
TMFILLPRGMWKGRTCCTNP*SSLMAFGFWPNY
VSSQETPITRCH*SVELLKSLNTSIRSTTAF*KT
NKTGPVPFNHAVIGASQELLTGRNCIAA*NLNT
LRPPSKVVTSLTCANIRAQPVG*F*LPVNICNH
CFSHLPPLATCCCYLSLLVGFSMLCQWLAFSTPS
FECSLVFCN*ELISKAEKDNKY*SKEKCN*NTA
LYCFILLYI*EIKGLVQPVESIEMTVINHTVLE
AEMQLPTLAFDGFSYL**PYPWSFGFSVCFFLFF
PSKLLFLGQAFMLPPFHIIISFDCSAVGNGDLL
E*CFSVQKL*SLSAPKLTEVIPYSFPFP*TNLL
IPLIQEFE*RWGTRTQMLSPHPLSCISQVQFKSK
ILLLELKQSNNLSNPLFLQRRKIKGTKVTAKAR
QLCSGKAETESPKSPSVWFSPQDCLLSFSPNAF
SCLFCA*FLALHIFHIDFDALYIGIRWQLNIF*I
TRR*SQMPE*RCSQCFPYAPGAPLIEASRIGAE
MK*A*RCCKCSLSLQLSDLLFLHDT*SAGHIKI
IPEVQAVPVISEKTGGYEIFPLPHLMRWI*FFKE
CFMPKIPACLAVLHCLICGHLLHCLAPNIQGP*
LRLVFSDALLKSGALQAPQASCWTET*LTGLRG
GIVENKSKTTPHPYFMSEITLFHTSCKACGERSH
KALS*TLRISKRKIFGEGGRKYVPCTPPLKHMA
VGNSIGLYVGGG*VGDVWSGKAGW*SSLLGTYS
WSQWIQVVQKVHTANSVLISKQTIIPEGKVCQGK
QTTQFPIRICPSTPETRLLSASPPVMDNSSYSQ
LT*LSQPMNSSLLGEATSHHTPEQS*GGILLPI
KGPLLRGKTCCLHHGFPLGSFQAWPNWGSGMEVA
LHPPSSA*VCLCNVSWHHTKSRRSKHPELFCWS
EIP*VSVLTQACSVSVL*SLRLWKEMGRGGRGN
VALRMLLIPLFLLGPVFREGGGWGKLDLVSSSIN
SHLHKM

Frame 2

QSFLPTIFVPGKVGFAQWLRPRKES*RAGNHYT
TTWAVLSGSRRHPRPRLRLRLRCTLKIQSHD*L
QVFHNQ*KRRNI*TKS*TQQ*KERKEKGGCEES
DCCYDRGEGC*FSLSRRSELYAD*QSGTKEACVS
LLDELRQESARHGHHGCKQLCEGL*RS*SFDSS
LGSQNHGVHPGRQNYRISL*AAPQVLEG*GSLC
SENSSSLRGKTP*YQCPNGGRSGISGFSTGSHSR
FKSNGGG*CRSGII*NQ*VSPKQQLT*SEPTEH
**AADSPE*MH*MGPDFHPGLPV*LQP*R*SGG
SEHL*AGNSPAIPCQLSSGAFSGKSPNEVSRIVT
*GF*LLQYAAEEVSPSTCHFAVWGARSAVCRPE
EHQLNCPEKA*NLEAGNQSLLCEVQ*SHLC*TR
EVGHHDSFGISSQHCSGSGRTERICYRGGC*LCS
KSCAGHWTVCHQGGAICRALCKHIA*SNPDQSE
LCGPRSNCCHQGHLPQIPQQV*KYHRHSV*ELR
LAG*ARCSSSYDLDCGRIC*KN*QCR*VTRKLPG
GFSR*KHPGAAHSAYCHSEAVSQETIRNTGASP
AGLEFGNTGF**S*PSRPGLYLLAPSLN*PCYS
*RSSLV*EATDL*GDGPY*ANSAG*ANLPHWFFG
LCVS*ASQCFCGRKSWNSS*TLANSSWEH*CR*
QPCWHYHCNEPGTASGYPLSR*SSRGSFKP*PR
SPSQCATGVLHADGSSGSPRRRTR*SGGTILHPI
IGACNLCSFTYTCCGQQWTE*PV*TLHRDRHGT
WWICGS*GCLATCSKG*RLGDFRNIYSPPRAHL
YGNELHQ*SSAAHDRFCNPV*QK*LWCHPQHSSG
HPYTTDAKPEH*CLPASQYLGPSHEDGTSE*PP
GGCEKQYRCLLLQLPHPTQCAFCRRWQNGAPGL
PCNMEGYSQ*K*TSVSD*GMSFKC*HCFQQVAKQ
QCLYYCQEECGRAGHAVPIPEAH*WHLDFGRTT
YPARKPQLHAVTEV*SS*SLSIHLSGLRQHFEK
LTRLVQYPSTML*SVQVKNS*LEEIVLLRRI*TH
*GHLAR**LV*PVLTLGHNLLDSFSFL*TFVTT
ASVTSHLLPPAAAICPYLWASPCCANGWLFLHP
LLSVVWYFVIESSFQKQKKTTNIKARKSVTETLH
FTVLYFCTYEKSRD*CNQ*KALK*LSLTTQSWR
QRCSYLP*LLMGSLTCSSLIPGHLDFQFAFFFF
SPPNSFSLAKPSCFPLSIL*SHLIALQLGTVIFL
NDVSVCKNYRACQHQS*QKLYLTPFLSPEQTC*
SH*FRNLSRDGEQEPRCCPLTPSPVFLRSSSNL
KFYF*S*NRVITYLTLFSYKGER*KAQRLPPRPV
SCVVAKPRPSLLSPRQCGFHHRTVSCRFPLMPS
PAFSVPSFWLFTYSILILTLCILASGGS*ISFE
LLEGKARCQNEGVASVSHMPLEPHLLRPAE*VQR
*SELRDVANALYPFSSLICSFFMILSLQGILRS
SQRFRQFLSSLKRLGDMKSSPYPT*CVGYDFSK
NASCPKYQPV*QCYTV*SAGTCCIAWHPIFRVHD
*DWSSQMPCLNQGHFRLHRRHVGLRPNSLDSEE
ESWKTRAKLPHTPISCLK*PCFIPVAKLVGSGP
TKHFLKP*ESPREKYLGKEGGNMSLAHHP*STWQ
*ETA*DCMWEVDRSVMCGAEKQVGKVPFLGLIP
GVSGYK*CRRFTLQIVFSSQSKLSFQKEKCVRA
SRQHNFLSEYVPQPPKQGFSQPPHQ*WITAPILS
*PD*ANP*TLHSLGKPPPITPLSRVREEFYFP*
KDLS*EAKPVASTTASLLAHSKLGQIGEVGWRL
PCIPPPLPECVFVMSAGIIQRAGEANTQNSFAGQ
RFPECLSSPKPALCLCCEA*DSGKKWGGGAGEM
LP*ECFSFLCSYWVLFFGRVGVGGSLTLCLRQ*
THIYTK*

Sequence NM_001030006

GTCAGAGTTTCCTGCCCACCATCTTTGTCCCTGGCAAAGTGGGTTTTGCGCAGTGGCTTAGACCTAGAAAAGAATCGTGACGGGCAGGAAACCATTACAC
CACCACCTGGGCTGTGCTCTCCGGCTCCCGCCGCCACCCCCGCCCTCGCCTTCGCCTCCGCCTCCGGTGCACATTAAAGATCCAAAGTCATGACTGACTC
CAAGTATTTCACAACCAATAAAAAAGGAGAAATATTTGAACTAAAAGCTGAACTCAACAATGAAAAGAAAGAAAAGAGAAAGGAGGCTGTGAAGAAAGTG
ATTGCTGCTATGACCGTGGGGAAGGATGTTAGTTCTCTCTTTCCAGACGTAGTGAACTGTATGCAGACTGACAATCTGGAACTAAAGAAGCTTGTGTATC
TCTACTTGATGAACTACGCCAAGAGTCAGCCAGACATGGCCATCATGGCTGTAAACAGCTTTGTGAAGGACTGTGAAGATCCTAATCCTTTGATTCGAGC
CTTGGCAGTCAGAACCATGGGGTGCATCCGGGTAGACAAAATTACAGAATATCTCTGTGAGCCGCTCCGCAAGTGCTTGAAGGATGAGGATCCCTATGTT
CGGAAAACAGCAGCAGTCTGCGTGGCAAAACTCCATGATATCAATGCCCAAATGGTGGAAGATCAGGGATTTCTGGATTCTCTACGGGATCTCATAGCAG
ATTCAAATCCAATGGTGGTGGCTAATGCCGTAGCGGCATTATCTGAAATCAGTGAGTCTCACCCAAACAGCAACTTACTTGATCTGAACCCACAGAACAT
TAATAAGCTGCTGACAGCCCTGAATGAATGCACTGAATGGGGCCAGATTTTCATCCTGGACTGCCTGTCTAATTACAACCCTAAAGATGATCGGGAGGCT
CAGAGCATCTGTGAGCGGGTAACTCCCCGGCTATCCCATGCCAACTCAGCAGTGGTGCTTTCAGCGGTAAAAGTCCTAATGAAGTTTCTAGAATTGTTAC
CTAAGGATTCTGACTACTACAATATGCTGCTGAAGAAGTTAGCCCCTCCACTTGTCACTTTGCTGTCTGGGGAGCCAGAAGTGCAGTATGTCGCCCTGAG
GAACATCAACTTAATTGTCCAGAAAAGGCCTGAAATCTTGAAGCAGGAAATCAAAGTCTTCTTTGTGAAGTACAATGATCCCATCTATGTTAAACTAGAG
AAGTTGGACATCATGATTCGTTTGGCATCTCAAGCCAACATTGCTCAGGTTCTGGCAGAACTGAAAGAATATGCTACAGAGGTGGATGTTGACTTTGTTC
GAAAAGCTGTGCGGGCCATTGGACGGTGTGCCATCAAGGTGGAGCAATCTGCAGAGCGCTGTGTAAGCACATTGCTTGATCTAATCCAGACCAAAGTGAA
TTATGTGGTCCAAGAAGCAATTGTTGTCATCAGGGACATCTTCCGCAAATACCCCAACAAGTATGAAAGTATCATCGCCACTCTGTGTGAGAACTTAGAC
TCGCTGGATGAGCCAGATGCTCGAGCAGCTATGATTTGGATTGTGGGAGAATATGCTGAAAGAATTGACAATGCAGATGAGTTACTAGAAAGCTTCCTGG
AGGGTTTTCACGATGAAAGCACCCAGGTGCAGCTCACTCTGCTTACTGCCATAGTGAAGCTGTTTCTCAAGAAACCATCAGAAACACAGGAGCTAGTCCA
GCAGGTCTTGAGTTTGGCAACACAGGATTCTGATAATCCTGACCTTCGAGACCGGGGCTATATTTATTGGCGCCTTCTCTCAACTGACCCTGTTACAGCT
AAAGAAGTAGTCTTGTCTGAGAAGCCACTGATCTCTGAGGAGACGGACCTTATTGAGCCAACTCTGCTGGATGAGCTAATCTGCCACATTGGTTCTTTGG
CCTCTGTGTATCATAAGCCTCCCAATGCTTTTGTGGAAGGAAGTCATGGAATTCATCGTAAACACTTGCCAATTCATCATGGGAGCACTGATGCAGGTGA
CAGCCCTGTTGGCACTACCACTGCAACGAACCTGGAACAGCCTCAGGTTATCCCCTCTCAAGGTGATCTTCTAGGGGATCTTTTAAACCTTGACCTCGGT
CCCCCAGTCAATGTGCCACAGGTGTCCTCCATGCAGATGGGAGCAGTGGATCTCCTAGGAGGAGGACTAGATAGTCTGCTTGGCAGTGACCTTGGCGGGG
GCATTGGAGGAAGTCCGGCA
GTGGGACAATCCTTCATCCCATCATCGGTGCCTGCAACCTTTGCTCCTTCACCTACACCTGCTGTGGTCAGCAGTGGACT
GAATGACCTGTTTGAACTCTCCACAGGGATAGGCATGGCACCTGGTGGATATGTGGCTCCTAAGGCTGTCTGGCTACCTGCAGTAAAGGCTAAAGGCTTG
GAGATTTCCGGAACATTTACTCACCGCCAAGGGCACATCTATATGGAAATGAACTTCACCAATAAAGCTCTGCAGCACATGACAGATTTTGCAATCCAGT
TTAACAAAAATAGCTTTGGTGTCATCCCCAGCACTCCTCTGGCCATCCATACACCACTGATGCCAAACCAGAGCATTGATGTCTCCCTGCCTCTCAATAC
CTTGGGCCCAGTCATGAAGATGGAACCTCTGAATAACCTCCAGGTGGCTGTGAAAAACAATATCGATGTCTTCTACTTCAGCTGCCTCATCCCACTCAAT
GTGCTTTTTGTAGAAGATGGCAAAATGGAGCGCCAGGTCTTCCTTGCAACATGGAAGGATATTCCCAATGAAAATGAACTTCAGTTTCAGATTAAGGAAT
GTCATTTAAATGCTGACACTGTTTCCAGCAAGTTGCAAAACAACAATGTTTATACTATTGCCAAGAGGAATGTGGAAGGGCAGGACATGCTGTACCAATC
CCTGAAGCTCACTAATGGCATTTGGATTTTGGCCGAACTACGTATCCAGCCAGGAAACCCCAATTACACGCTGTCACTGAAGTGTAGAGCTCCTGAAGTC
TCTCAATACATCTATCAGGTCTACGACAGCATTTTGAAAAACTAACAAGACTGGTCCAGTACCCTTCAACCATGCTGTGATCGGTGCAAGTCAAGAACTC
TTAACTGGAAGAAATTGTATTGCTGCGTAGAATCTGAACACACTGAGGCCACCTAGCAAGGTAGTAACTAGTCTAACCTGTGCTAACATTAGGGCACAAC
CTGTTGGATAGTTTTAGCTTCCTGTGAACATTTGTAACCACTGCTTCAGTCACCTCCCACCTCTTGCCACCTGCTGCTGCTATCTGTCCTTACTTGTGGG
CTTCTCCATGCTGTGCCAATGGCTGGCTTTTTCTACACCCTCTTTTGAGTGTAGTTTGGTATTTTGTAATTGAGAGCTCATTTCAAAAGCAGAAAAAGAC
AACAAATATTAAAGCAAGGAAAAGTGTAACTGAAACACTGCACTTTACTGTTTTATACTTTTGTACATATGAGAAATCAAGGGATTAGTGCAACCAGTAG
AAAGCATTGAAATGACTGTCATTAACCACACAGTCCTGGAGGCAGAGATGCAGTTACCTACCCTAGCTTTTGATGGGTTCTCTTACCTGTAGTAGCCTTA
TCCCTGGTCATTTGGATTTTCAGTTTGCTTTTTTCTTTTTTTCCCCTCCAAACTCCTTTTCCTTGGCCAAGCCTTCATGCTTCCCCCTTTCCATATTATA
ATCTCATTTGATTGCTCTGCAGTTGGGAACGGTGATCTTCTTGAATGATGTTTCAGTGTGCAAAAACTATAGAGCCTGTCAGCACCAAAGCTGACAGAAG
TTATACCTTACTCCTTTCCTTTCCCCTGAACAAACCTGCTAATCCCACTAATTCAGGAATTTGAGTAGAGATGGGGAACAAGAACCCAGATGCTGTCCCC
TCACCCCCTCTCCTGTATTTCTCAGGTCCAGTTCAAATCTAAAATTCTACTTTTAGAGTTGAAACAGAGTAATAACTTATCTAACCCTCTTTTCCTACAA
AGGAGAAAGATAAAAGGCACAAAGGTTACCGCCAAGGCCCGTCAGCTGTGTAGTGGCAAAGCCGAGACCGAGTCTCCTAAGTCCCCGTCAGTGTGGTTTT
CACCACAGGACTGTCTCTTGTCGTTTTCCCCTAATGCCTTCTCCTGCCTTTTCTGTGCCTAGTTTTTGGCTCTTCACATATTCCATATTGATTTTGACGC
TCTGTATATTGGCATCAGGTGGCAGCTGAATATCTTTTGAATTACTCGAAGGTAAAGCCAGATGCCAGAATGAAGGTGTAGCCAGTGTTTCCCATATGCC
CCTGGAGCCCCACTTATTGAGGCCAGCAGAATAGGTGCAGAGATGAAGTGAGCTTAGAGATGTTGCAAATGCTCTTTATCCCTTCAGCTCTCTGATCTGC
TCTTTCTTCATGATACTTAGTCTGCAGGGCATATTAAGATCATCCCAGAGGTTCAGGCAGTTCCTGTCATCTCTGAAAAGACTGGGGGATATGAAATCTT
CCCCCTACCCCACTTAATGCGTTGGATATGATTTTTCAAAGAATGCTTCATGCCCAAAATACCAGCCTGTTTAGCAGTGTTACACTGTTTGATCTGCGGG
CACTTGTTGCATTGCCTGGCACCCAATATTCAGGGTCCATGACTAAGACTGGTCTTCTCAGATGCCCTGCTTAAATCAGGGGCACTTCAGGCTCCACAGG
CGTCATGTTGGACTGAGACCTAACTCACTGGACTCAGAGGAGGAATCGTGGAAAACAAGAGCAAAACTACCCCACACCCCTATTTCATGTCTGAAATAAC
CCTGTTTCATACCAGTTGCAAAGCTTGTGGGGAGCGGTCCCACAAAGCACTTTCTTAAACCTTGAGAATCTCCAAGAGAAAAATATTTGGGGAAGGAGGG
AGGAAATATGTCCCTTGCACACCACCCCTGAAGCACATGGCAGTAGGAAACAGCATAGGATTGTATGTGGGAGGTGGATAGGTCGGTGATGTGTGGAGCG
GAAAAGCAGGTTGGTAAAGTTCCCTTCTTGGGACTTATTCCTGGAGTCAGTGGATACAAGTAGTGCAGAAGGTTCACACTGCAAATAGTGTTCTCATCTC
AAAGCAAACTATCATTCCAGAAGGAAAAGTGTGTCAGGGCAAGCAGACAACACAATTTCCTATCAGAATATGTCCCTCAACCCCCGAAACAAGGCTTCTC
TCAGCCTCCCCACCAGTGATGGATAACAGCTCCTATTCTCAGCTGACCTGACTGAGCCAACCCATGAACTCTTCACTCCTTGGGGAAGCCACCTCCCATC
ACACCCCTGAGCAGAGTTAGGGAGGAATTCTACTTCCCATAAAAGGACCTCTCCTGAGAGGCAAAACCTGTTGCCTCCACCACGGCTTCCCTCTTGGCTC
ATTCCAAGCTTGGCCAAATTGGGGAAGTGGGATGGAGGTTGCCCTGCATCCCCCCTCCTCTGCCTGAGTGTGTCTTTGTAATGTCAGCTGGCATCATACA
AAGAGCAGGAGAAGCAAACACCCAGAACTCTTTTGCTGGTCAGAGATTCCCTGAGTGTCTGTCCTCACCCAAGCCTGCTCTGTGTCTGTGTTGTGAAGCT
TGAGACTCTGGAAAGAAATGGGGAGGGGGGGCAGGGGAAATGTTGCCCTAAGAATGCTTCTCATTCCTCTGTTCTTATTGGGTCCTGTTTTTCGGGAGGG
TGGGGGTTGGGGGAAGCTTGACCTTGTGTCTTCGTCAATAAACTCACATTTACACAAAATGAA
  • refseq_AP2B1.F1 (forward primer)
  • refseq_AP2B1.R1 (reverse primer)
  • Single exon skipping

Frame 0

VRVSCPPSLSLAKWVLRSGLDLEKNRDGQETIT
PPPGLCSPAPAATPALAFASASGAH*RSKVMTDS
KYFTTNKKGEIFELKAELNNEKKEKRKEAVKKV
IAAMTVGKDVSSLFPDVVNCMQTDNLELKKLVY
LYLMNYAKSQPDMAIMAVNSFVKDCEDPNPLIRA
LAVRTMGCIRVDKITEYLCEPLRKCLKDEDPYV
RKTAAVCVAKLHDINAQMVEDQGFLDSLRDLIA
DSNPMVVANAVAALSEISESHPNSNLLDLNPQNI
NKLLTALNECTEWGQIFILDCLSNYNPKDDREA
QSICERVTPRLSHANSAVVLSAVKVLMKFLELL
PKDSDYYNMLLKKLAPPLVTLLSGEPEVQYVALR
NINLIVQKRPEILKQEIKVFFVKYNDPIYVKLE
KLDIMIRLASQANIAQVLAELKEYATEVDVDFV
RKAVRAIGRCAIKVEQSAERCVSTLLDLIQTKVN
YVVQEAIVVIRDIFRKYPNKYESIIATLCENLD
SLDEPDARAAMIWIVGEYAERIDNADELLESFL
EGFHDESTQVQLTLLTAIVKLFLKKPSETQELVQ
QVLSLATQDSDNPDLRDRGYIYWRLLSTDPVTA
KEVVLSEKPLISEETDLIEPTLLDELICHIGSL
ASVYHKPPNAFVEGSHGIHRKHLPIHHGSTDAGD
SPVGTTTATNLEQPQVIPSQGDLLGDLLNLDLG
PPVNVPQVSSMQMGAVDLLGGGLDSLLGSDLGG
GIGGSPA
VGQSFIPSSVPATFAPSPTPAVVSSGL
NDLFELSTGIGMAPGGYVAPKAVWLPAVKAKGL
EISGTFTHRQGHIYMEMNFTNKALQHMTDFAIQ
FNKNSFGVIPSTPLAIHTPLMPNQSIDVSLPLNT
LGPVMKMEPLNNLQVAVKNNIDVFYFSCLIPLN
VLFVEDGKMERQVFLATWKDIPNENELQFQIKE
CHLNADTVSSKLQNNNVYTIAKRNVEGQDMLYQS
LKLTNGIWILAELRIQPGNPNYTLSLKCRAPEV
SQYIYQVYDSILKN*QDWSSTLQPCCDRCKSRT
LNWKKLYCCVESEHTEAT*QGSN*SNLC*H*GTT
CWIVLASCEHL*PLLQSPPTSCHLLLLSVLTCG
LLHAVPMAGFFYTLF*V*FGIL*LRAHFKSRKR
QQILKQGKV*LKHCTLLFYTFVHMRNQGISATSR
KH*NDCH*PHSPGGRDAVTYPSF*WVLLPVVAL
SLVIWIFSLLFSFFPLQTPFPWPSLHASPFPYY
NLI*LLCSWER*SS*MMFQCAKTIEPVSTKADRS
YTLLLSFPLNKPANPTNSGI*VEMGNKNPDAVP
SPPLLYFSGPVQI*NSTFRVETE**LI*PSFPT
KEKDKRHKGYRQGPSAV*WQSRDRVS*VPVSVVF
TTGLSLVVFP*CLLLPFLCLVFGSSHIPY*F*R
SVYWHQVAAEYLLNYSKVKPDARMKV*PVFPIC
PWSPTY*GQQNRCRDEVSLEMLQMLFIPSAL*SA
LSS*YLVCRAY*DHPRGSGSSCHL*KDWGI*NL
PPTPLNALDMIFQRMLHAQNTSLFSSVTLFDLR
ALVALPGTQYSGSMTKTGLLRCPA*IRGTSGSTG
VMLD*DLTHWTQRRNRGKQEQNYPTPLFHV*NN
PVSYQLQSLWGAVPQSTFLNLENLQEKNIWGRR
EEICPLHTTPEAHGSRKQHRIVCGRWIGR*CVER
KSRLVKFPSWDLFLESVDTSSAEGSHCK*CSHL
KANYHSRRKSVSGQADNTISYQNMSLNPRNKAS
LSLPTSDG*QLLFSADLTEPTHELFTPWGSHLPS
HP*AELGRNSTSHKRTSPERQNLLPPPRLPSWL
IPSLAKLGKWDGGCPASPLLCLSVSL*CQLASY
KEQEKQTPRTLLLVRDSLSVCPHPSLLCVCVVKL
ETLERNGEGGQGKCCPKNASHSSVLIGSCFSGG
WGLGEA*PCVFVNKLTFTQNE

Frame 1

SEFPAHHLCPWQSGFCAVA*T*KRIVTGRKPLH
HHLGCALRLPPPPPPSPSPPPPVHIKDPKS*LT
PSISQPIKKEKYLN*KLNSTMKRKKRERRL*RK*
LLL*PWGRMLVLSFQT**TVCRLTIWN*RSLCI
ST**TTPRVSQTWPSWL*TAL*RTVKILIL*FE
PWQSEPWGASG*TKLQNISVSRSASA*RMRIPMF
GKQQQSAWQNSMISMPKWWKIRDFWILYGIS*Q
IQIQWWWLMP*RHYLKSVSLTQTATYLI*THRT
LISC*QP*MNALNGARFSSWTACLITTLKMIGRL
RASVSG*LPGYPMPTQQWCFQR*KS**SF*NCY
LRILTTTICC*RS*PLHLSLCCLGSQKCSMSP*
GTST*LSRKGLKS*SRKSKSSL*STMIPSMLN*R
SWTS*FVWHLKPTLLRFWQN*KNMLQRWMLTLF
EKLCGPLDGVPSRWSNLQSAV*AHCLI*SRPK*
IMWSKKQLLSSGTSSANTPTSMKVSSPLCVRT*T
RWMSQMLEQL*FGLWENMLKELTMQMSY*KASW
RVFTMKAPRCSSLCLLP**SCFSRNHQKHRS*S
SRS*VWQHRILIILTFETGAIFIGAFSQLTLLQL
KK*SCLRSH*SLRRRTLLSQLCWMS*SATLVLW
PLCIISLPMLLWKEVMEFIVNTCQFIMGALMQV
TALLALPLQRTWNSLRLSPLKVIF*GIF*TLTSV
PQSMCHRCPPCRWEQWIS*EED*IVCLAVTLAG
ALEEVRQ
WDNPSSHHRCLQPLLLHLHLLWSAVD
*MTCLNSPQG*AWHLVDMWLLRLSGYLQ*RLKAW
RFPEHLLTAKGTSIWK*TSPIKLCST*QILQSS
LTKIALVSSPALLWPSIHH*CQTRALMSPCLSI
PWAQS*RWNL*ITSRWL*KTISMSSTSAASSHSM
CFL*KMAKWSARSSLQHGRIFPMKMNFSFRLRN
VI*MLTLFPASCKTTMFILLPRGMWKGRTCCTN
P*SSLMAFGFWPNYVSSQETPITRCH*SVELLKS
LNTSIRSTTAF*KTNKTGPVPFNHAVIGASQEL
LTGRNCIAA*NLNTLRPPSKVVTSLTCANIRAQ
PVG*F*LPVNICNHCFSHLPPLATCCCYLSLLVG
FSMLCQWLAFSTPSFECSLVFCN*ELISKAEKD
NKY*SKEKCN*NTALYCFILLYI*EIKGLVQPV
ESIEMTVINHTVLEAEMQLPTLAFDGFSYL**PY
PWSFGFSVCFFLFFPSKLLFLGQAFMLPPFHII
ISFDCSAVGNGDLLE*CFSVQKL*SLSAPKLTE
VIPYSFPFP*TNLLIPLIQEFE*RWGTRTQMLSP
HPLSCISQVQFKSKILLLELKQSNNLSNPLFLQ
RRKIKGTKVTAKARQLCSGKAETESPKSPSVWF
SPQDCLLSFSPNAFSCLFCA*FLALHIFHIDFDA
LYIGIRWQLNIF*ITRR*SQMPE*RCSQCFPYA
PGAPLIEASRIGAEMK*A*RCCKCSLSLQLSDL
LFLHDT*SAGHIKIIPEVQAVPVISEKTGGYEIF
PLPHLMRWI*FFKECFMPKIPACLAVLHCLICG
HLLHCLAPNIQGP*LRLVFSDALLKSGALQAPQ
ASCWTET*LTGLRGGIVENKSKTTPHPYFMSEIT
LFHTSCKACGERSHKALS*TLRISKRKIFGEGG
RKYVPCTPPLKHMAVGNSIGLYVGGG*VGDVWS
GKAGW*SSLLGTYSWSQWIQVVQKVHTANSVLIS
KQTIIPEGKVCQGKQTTQFPIRICPSTPETRLL
SASPPVMDNSSYSQLT*LSQPMNSSLLGEATSH
HTPEQS*GGILLPIKGPLLRGKTCCLHHGFPLGS
FQAWPNWGSGMEVALHPPSSA*VCLCNVSWHHT
KSRRSKHPELFCWSEIP*VSVLTQACSVSVL*S
LRLWKEMGRGGRGNVALRMLLIPLFLLGPVFREG
GGWGKLDLVSSSINSHLHKM

Frame 2

QSFLPTIFVPGKVGFAQWLRPRKES*RAGNHYT
TTWAVLSGSRRHPRPRLRLRLRCTLKIQSHD*L
QVFHNQ*KRRNI*TKS*TQQ*KERKEKGGCEES
DCCYDRGEGC*FSLSRRSELYAD*QSGTKEACVS
LLDELRQESARHGHHGCKQLCEGL*RS*SFDSS
LGSQNHGVHPGRQNYRISL*AAPQVLEG*GSLC
SENSSSLRGKTP*YQCPNGGRSGISGFSTGSHSR
FKSNGGG*CRSGII*NQ*VSPKQQLT*SEPTEH
**AADSPE*MH*MGPDFHPGLPV*LQP*R*SGG
SEHL*AGNSPAIPCQLSSGAFSGKSPNEVSRIVT
*GF*LLQYAAEEVSPSTCHFAVWGARSAVCRPE
EHQLNCPEKA*NLEAGNQSLLCEVQ*SHLC*TR
EVGHHDSFGISSQHCSGSGRTERICYRGGC*LCS
KSCAGHWTVCHQGGAICRALCKHIA*SNPDQSE
LCGPRSNCCHQGHLPQIPQQV*KYHRHSV*ELR
LAG*ARCSSSYDLDCGRIC*KN*QCR*VTRKLPG
GFSR*KHPGAAHSAYCHSEAVSQETIRNTGASP
AGLEFGNTGF**S*PSRPGLYLLAPSLN*PCYS
*RSSLV*EATDL*GDGPY*ANSAG*ANLPHWFFG
LCVS*ASQCFCGRKSWNSS*TLANSSWEH*CR*
QPCWHYHCNEPGTASGYPLSR*SSRGSFKP*PR
SPSQCATGVLHADGSSGSPRRRTR*SAWQ*PWRG
HWRKSG
SGTILHPIIGACNLCSFTYTCCGQQWT
E*PV*TLHRDRHGTWWICGS*GCLATCSKG*RL
GDFRNIYSPPRAHLYGNELHQ*SSAAHDRFCNPV
*QK*LWCHPQHSSGHPYTTDAKPEH*CLPASQY
LGPSHEDGTSE*PPGGCEKQYRCLLLQLPHPTQ
CAFCRRWQNGAPGLPCNMEGYSQ*K*TSVSD*GM
SFKC*HCFQQVAKQQCLYYCQEECGRAGHAVPI
PEAH*WHLDFGRTTYPARKPQLHAVTEV*SS*S
LSIHLSGLRQHFEKLTRLVQYPSTML*SVQVKNS
*LEEIVLLRRI*TH*GHLAR**LV*PVLTLGHN
LLDSFSFL*TFVTTASVTSHLLPPAAAICPYLW
ASPCCANGWLFLHPLLSVVWYFVIESSFQKQKKT
TNIKARKSVTETLHFTVLYFCTYEKSRD*CNQ*
KALK*LSLTTQSWRQRCSYLP*LLMGSLTCSSL
IPGHLDFQFAFFFFSPPNSFSLAKPSCFPLSIL*
SHLIALQLGTVIFLNDVSVCKNYRACQHQS*QK
LYLTPFLSPEQTC*SH*FRNLSRDGEQEPRCCP
LTPSPVFLRSSSNLKFYF*S*NRVITYLTLFSYK
GER*KAQRLPPRPVSCVVAKPRPSLLSPRQCGF
HHRTVSCRFPLMPSPAFSVPSFWLFTYSILILT
LCILASGGS*ISFELLEGKARCQNEGVASVSHMP
LEPHLLRPAE*VQR*SELRDVANALYPFSSLIC
SFFMILSLQGILRSSQRFRQFLSSLKRLGDMKS
SPYPT*CVGYDFSKNASCPKYQPV*QCYTV*SAG
TCCIAWHPIFRVHD*DWSSQMPCLNQGHFRLHR
RHVGLRPNSLDSEEESWKTRAKLPHTPISCLK*
PCFIPVAKLVGSGPTKHFLKP*ESPREKYLGKEG
GNMSLAHHP*STWQ*ETA*DCMWEVDRSVMCGA
EKQVGKVPFLGLIPGVSGYK*CRRFTLQIVFSS
QSKLSFQKEKCVRASRQHNFLSEYVPQPPKQGFS
QPPHQ*WITAPILS*PD*ANP*TLHSLGKPPPI
TPLSRVREEFYFP*KDLS*EAKPVASTTASLLA
HSKLGQIGEVGWRLPCIPPPLPECVFVMSAGIIQ
RAGEANTQNSFAGQRFPECLSSPKPALCLCCEA
*DSGKKWGGGAGEMLP*ECFSFLCSYWVLFFGR
VGVGGSLTLCLRQ*THIYTK*

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