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Sequences

Sequence NM_001002243

GCATGATGGGAGAGTGTGTGGAGTGGGCGGGGGGTCTCCGCGGAGGAGGTGGAGGAGGCGGCGGCGGCGGCGGAAGAGGGCGGAGGGTAGTGGGATGGGG GTCCCGCGGCAGCGGTGAAACTCCGGGTGGGCGTCCATGGTGCTGCTGCGCTGACAGGGCTGTGAGCAGCCGGCCTTCCGCTCTCACCAGTTCCGCGTCG GAATAGACGGTCCTTCCCCGGGGAGTCAGTTCCTCCCCGGGCCCCTGAGCCATGCCCATCGCAGCCGCCCCGAAGGAGCCAGGTGTAAATTAATTATTTG AAAGCAACTGAACAATGGAGCCAGACATCATTCGAATGTACTCTTCATCCCCACCACCATTAGACAATGGAGCAGAGGATGATGATGATGATGAATTTGG GGAATTTGGTGGGTTTTCAGAAGTTAGCCCTTCTGGTGTAGGGTTTGTTGATTTCGATACACCAGATTATACTCGTCCCAAGGAAGAGTTTGTACCTTCA AACCATTTTATGCCAATTCATGAATTCTCAGAAAATGTAGATAGCCTTACAAGCTTTAAGTCCATTAAAAATGGTAATGATAAGGACATCACTGCTGAAC TTTCTGCTCCTGTGAAAGGACAGTCTGATGTTTTACTTTCTACCACCAGCAAAGAAATAATTTCATCTGAAATGTTAGCTACTTCCATTGATGGCATGGA AAGACCAGGAAATTTAAATAAAGTAGTGGAGCAGAGACAGAATGTTGGAACACTTGAAAGTTTCTCTCCAGGAGATTTTAGAACTAATATGAATGTTGTT CATCAAAACAAGCAGTTAGAGAGCTGCAATGGTGAAAAGCCTCCTTGTCTGGAGATTCTAACAAATGGGTTTGCAGTGTTGGAAACTGTAAATCCTCAGG GAACAGATGATCTGGACAATGTAGCTGATTCAAAGGGACGGAAGCCTCTTAGCACTCATAGCACTGAGTATAATTTAGACTCTGTACCTAGTCCTGCTGA GGAATTTGCAGATTTTGCCACATTTTCCAAAAAGGAAAGGATACAATTAGAAGAAATAGAATGTGCAGTTTTAAATGATAGAGAAGCACTAACCATTCGG GAAAACAATAAAATTAATAGAGTCAATGAACTGAATTCTGTAAAAGAAGTGGCTTTGGGTAGAAGCTTGGATAACAAAGGAGACACTGATGGAGAGGATC AGGTTTGTGTTTCAGAAATAAGCATAGTGACTAACAGAGGTTTCAGTGTTGAAAAACAAGGCCTTCCAACACTGCAACAGGATGAATTTTTACAGTCAGG TGTTCAGTCAAAGGCTTGGAGTTTGGTAGACTCAGCTGATAATTCAGAAGCCATTAGGAGAGAACAATGTAAAACTGAAGAAAAACTTGACTTACTTACT TCTAAATGTGCTCACCTATGCATGGATTCTGTTAAAACTTCTGATGATGAAGTTGGTTCTCCCAAAGAAGAAAGTAGAAAGTTTACTAATTTCCAAAGCC CAAACATTGACCCCACAGAAGAAAATGATTTGGATGATTCTTTAAGTGTAAAAAATGGTGATAGTAGTAATGACTTTGTGACTTGCAATGATATCAATGA AGATGATTTTGGTGATTTTGGTGACTTTGGCTCTGCCAGTGGCTCAACTCCACCTTTTGTTACTGGTACTCAAGATTCAATGAGTGATGCCACTTTTGAA GAGTCTTCAGAGCACTTTCCACATTTTAGTGAACCAGGTGATGACTTTGGAGAATTTGGGGATATAAATGCTGTTTCTTGCCAAGAGGAGACAATATTAA CAAAGTCAGACCTAAAACAGACTTCTGATAATTTATCAGAAGAATGTCAATTGGCAAGAAAATCTAGTGGAACAGGCACTGAACCTGTTGCAAAACTTAA AAATGGGCAAGAAGGTGAGATTGGACATTTTGATTCTGTGCCAAATATTCAGGATGACTGCAATGGTTTTCAAGACTCTGATGATTTTGCAGACTTCAGT TCAGCTGGTCCTAGCCAAGTTGTAGATTGGAATGCTTTTGAGGATGAACAAAAAGATAGTTGTTCTTGGGCTGCTTTTGGAGACCAGCAGGCTACTGAAT CTCATCATCGAAAGGAAGCCTGGCAGTCACATAGGACAGATGAAAATATTGATACTCCAGGAACCCCCAAAACGCACAGTGTACCTTCAGCAACTTCCAA AGGAGCAGTTGCTAGTGGCCATTTACAGGAATCAGCCACTTCAGTTCAGACAGCTTTATTAAACCGCCTGGAGCGAATTTTCGAAGCATGTTTTCCTTCC ATACTTGTCCCTGATGCTGAAGAGGAAGTTACTTCCCTGAAGCACTTGCTGGAAACAAGCACTTTGCCAATAAAAACGAGAGAGGCCTTACCTGAAAGTG GGGAATTGCTAGATGTGTGGACTGAGCTACAGGATATCCATGATGCACATGGCTTGAGATACCAGTGGGGCGGCTCCCATAGCAACAAGAAGCTTTTGTC CTCCTTGGGAATAGACACCCGAAACATTCTCTTCACGGGCAATAAGAAGCAGCCTGTTATAGTGCCCATGTATGCAGCAGGATTGGGTATGTTAGAGCCC ACCAAGGAACCACTGAAACCACTTTCTGCTGCAGAAAAAATAGCTTCCATCGGTCAGACAGCCACCATGTCACCAGATATGAACACATGTACATCTGATC AGTTCCAGGAGTCTCTACCACCCGTCCAGTTTGACTGGAGTAGCAGTGGCCTTACTAACCCTTTAGATGGTGTGGATCCGGAGTTGTATGAGTTAACAAC TTCTAAGCTGGAAATCTCCACCTCAAGCCTCAAAGTGACTGATGCATTTGCAAGACTCATGTCTACAGTAGAGAAGACAAGCACATCTACCAGGAAACCG AAAAGAGAAGAGCACCTAAGTGAAGAAGCTATCAAGGTGATCGCTGGCCTTCCTGACTTAACATTCATGCATGCCAAGGTGTTGATGTTCCCAGCCACGT TAACACCTTCCACAAGCTCTCAAGAAAAAGCAGACGGATAACTGATGTGAATTGGACAGTTTCTATTGCTTTTCCTTTTTTCCATCCCTTCCCTACCATC AAAAGCATACCTGCTCTAATTAAAAAAAAAAAAAAAAAAAATTCAAGTTCAGCTGATTTGTTGGTAAGCCGCACTAGAAAGGTATACATAGTAATGTATA TTTATTTACATACTGAAGTCCTAAATTTATATTAGAAAAATGTAAATAATCGGGGGTAAACATTTTTGAAGATTTATTCTTTTTGTGTTGCTGGGGTGTA TACATTTATGTCTTTGTGAAATACACTGGTGGTGTCCTTCTTACAAAACTTTTGAAATAAAAAAAAAACTCAAATCTTCACTGTCTGTGAAATCCCCTTC AGTCTTTTCAGATTGCATTGACTGTCCTCTTGATTTTTCATATTACATGTCAAATTACTTTTGCTATCATAAATAAGCTCCAAAGTCCCCCATTTAATTT TTTTTTAATTTTGTGTATGATGGGTTTCAGATCTGGCTTTTGTTAACATTTTGGGGCTTTTTTAATCTTTTCAATCTGGCGTATTGCTGTTTGACCTTTT GCAAGGTACTTAATTGCTCTTTTGTTATAGGGTATGGATCATTGTCAGAACTTGATTGGAGGGGTTTAAAGAGATTGTGTCTGTTTAAAATCAGTATGAT TCAGAGAAGGACCAAATTATATGAATGTCTTACAATGGAATTTACTTGTTACTGATTTTTTTGTTCTATTGTACCACTATTTTTTGAGGATTTTGCACAG TGTAAAATGACATAATCATAGATTGCTATGGTTTAGGCTGTATATACAGTGAAAACTATGGGTTTTAAATGTTTGGGGAAATTCCTATGGAAAAAAGAGA GACATGTAGAAGAACCTCTAACAAGGTTAATGTGCATGCCCAAGGTCTTTTGAAATTTCAGTGTGTAAATTTCCTTTTAGCTTATACAAAAATAAAATAA TTTAAAAGAAA

refseq_AFTPH.F1 (forward primer)
refseq_AFTPH.R1 (reverse primer)
Single exon skipping

Frame 0

A*WESVWSGRGVSAEEVEEAAAAAEEGGG*WDG GPAAAVKLRVGVHGAAALTGL*AAGLPLSPVPRR NRRSFPGESVPPRAPEPCPSQPPRRSQV*INYL KATEQWSQTSFECTLHPHHH*TMEQRMMMMMNL GNLVGFQKLALLV*GLLISIHQIILVPRKSLYLQ TILCQFMNSQKM*IALQALSPLKMVMIRTSLLN FLLL*KDSLMFYFLPPAKK*FHLKC*LLPLMAW KDQEI*IK*WSRDRMLEHLKVSLQEILELI*MLF IKTSS*RAAMVKSLLVWRF*QMGLQCWKL*ILR EQMIWTM*LIQRDGSLLALIALSII*TLYLVLL RNLQILPHFPKRKGYN*KK*NVQF*MIEKH*PFG KTIKLIESMN*IL*KKWLWVEAWITKETLMERI RFVFQK*A**LTEVSVLKNKAFQHCNRMNFYSQ VFSQRLGVW*TQLIIQKPLGENNVKLKKNLTYLL LNVLTYAWILLKLLMMKLVLPKKKVESLLISKA QTLTPQKKMIWMIL*V*KMVIVVMTL*LAMISM KMILVILVTLALPVAQLHLLLLVLKIQ*VMPLLK SLQSTFHILVNQVMTLENLGI*MLFLAKRRQY* QSQT*NRLLIIYQKNVNWQENLVEQALNLLQNL KMGKKVRLDILILCQIFRMTAMVFKTLMILQTSV QLVLAKL*IGMLLRMNKKIVVLGLLLETSRLLN LIIERKPGSHIGQMKILILQEPPKRTVYLQQLP KEQLLVAIYRNQPLQFRQLY*TAWSEFSKHVFLP YLSLMLKRKLLP*STCWKQALCQ*KRERPYLKV GNC*MCGLSYRISMMHMA*DTSGAAPIATRSFC PPWE*TPETFSSRAIRSSLL*CPCMQQDWVC*SP PRNH*NHFLLQKK*LPSVRQPPCHQI*THVHLI SSRSLYHPSSLTGVAVALLTL*MVWIRSCMS*Q LLSWKSPPQASK*LMHLQDSCLQ*RRQAHLPGNR KEKST*VKKLSR*SLAFLT*HSCMPRC*CSQPR *HLPQALKKKQTDN*CELDSFYCFSFFPSLPYH QKHTCSN*KKKKKKFKFS*FVGKPH*KGIHSNVY LFTY*SPKFILEKCK*SGVNIFEDLFFLCCWGV YIYVFVKYTGGVLLTKLLK*KKNSNLHCL*NPL QSFQIALTVLLIFHITCQITFAIINKLQSPPFNF FLILCMMGFRSGFC*HFGAFLIFSIWRIAV*PF ARYLIALLL*GMDHCQNLIGGV*RDCVCLKSV* FREGPNYMNVLQWNLLVTDFFVLLYHYFLRILHS VK*HNHRLLWFRLYIQ*KLWVLNVWGNSYGKKR DM*KNL*QG*CACPRSFEISVCKFPFSLYKNKI I*KK

Frame 1

HDGRVCGVGGGSPRRRWRRRRRRRKRAEGSGMG VPRQR*NSGWASMVLLR*QGCEQPAFRSHQFRV GIDGPSPGSQFLPGPLSHAHRSRPEGARCKLII* KQLNNGARHHSNVLFIPTTIRQWSRG*****IW GIWWVFRS*PFWCRVC*FRYTRLYSSQGRVCTF KPFYANS*ILRKCR*PYKL*VH*KW***GHHC*T FCSCERTV*CFTFYHQQRNNFI*NVSYFH*WHG KTRKFK*SSGAETECWNT*KFLSRRF*N*YECC SSKQAVRELQW*KASLSGDSNKWVCSVGNCKSSG NR*SGQCS*FKGTEAS*HS*H*V*FRLCT*SC* GICRFCHIFQKGKDTIRRNRMCSFK**RSTNHS GKQ*N**SQ*TEFCKRSGFG*KLG*QRRH*WRGS GLCFRNKHSD*QRFQC*KTRPSNTATG*IFTVR CSVKGLEFGRLS**FRSH*ERTM*N*RKT*LTY F*MCSPMHGFC*NF***SWFSQRRK*KVY*FPKP KH*PHRRK*FG*FFKCKKW*****LCDLQ*YQ* R*FW*FW*LWLCQWLNSTFCYWYSRFNE*CHF* RVFRALSTF**TR**LWRIWGYKCCFLPRGDNIN KVRPKTDF**FIRRMSIGKKI*WNRH*TCCKT* KWARR*DWTF*FCAKYSG*LQWFSRL**FCRLQ FSWS*PSCRLECF*G*TKR*LFLGCFWRPAGY*I SSSKGSLAVT*DR*KY*YSRNPQNAQCTFSNFQ RSSC*WPFTGISHFSSDSFIKPPGANFRSMFSF HTCP*C*RGSYFPEALAGNKHFANKNERGLT*KW GIARCVD*ATGYP*CTWLEIPVGRLP*QQEAFV LLGNRHPKHSLHGQ*EAACYSAHVCSRIGYVRA HQGTTETTFCCRKNSFHRSDSHHVTRYEHMYI*S VPGVSTTRPV*LE*QWPY*PFRWCGSGVV*VNN F*AGNLHLKPQSD*CICKTHVYSREDKHIYQET EKRRAPK*RSYQGDRWPS*LNIHACQGVDVPSHV NTFHKLSRKSRRITDVNWTVSIAFPFFHPFPTI KSIPALIKKKKKKNSSSADLLVSRTRKVYIVMY IYLHTEVLNLY*KNVNNRG*TFLKIYSFCVAGVY TFMSL*NTLVVSFLQNF*NKKKTQIFTVCEIPF SLFRLH*LSS*FFILHVKLLLLS*ISSKVPHLI FF*FCV*WVSDLAFVNILGLF*SFQSGVLLFDLL QGT*LLFCYRVWIIVRT*LEGFKEIVSV*NQYD SEKDQII*MSYNGIYLLLIFLFYCTTIF*GFCT V*NDIIIDCYGLGCIYSENYGF*MFGEIPMEKRE TCRRTSNKVNVHAQGLLKFQCVNFLLAYTKIK* FKR

Frame 2

MMGECVEWAGGLRGGGGGGGGGGGRGRRVVGWG SRGSGETPGGRPWCCCADRAVSSRPSALTSSAS E*TVLPRGVSSSPGP*AMPIAAAPKEPGVN*LF ESN*TMEPDIIRMYSSSPPPLDNGAEDDDDDEFG EFGGFSEVSPSGVGFVDFDTPDYTRPKEEFVPS NHFMPIHEFSENVDSLTSFKSIKNGNDKDITAE LSAPVKGQSDVLLSTTSKEIISSEMLATSIDGME RPGNLNKVVEQRQNVGTLESFSPGDFRTNMNVV HQNKQLESCNGEKPPCLEILTNGFAVLETVNPQ GTDDLDNVADSKGRKPLSTHSTEYNLDSVPSPAE EFADFATFSKKERIQLEEIECAVLNDREALTIR ENNKINRVNELNSVKEVALGRSLDNKGDTDGED QVCVSEISIVTNRGFSVEKQGLPTLQQDEFLQSG VQSKAWSLVDSADNSEAIRREQCKTEEKLDLLT SKCAHLCMDSVKTSDDEVGSPKEESRKFTNFQS PNIDPTEENDLDDSLSVKNGDSSNDFVTCNDINE DDFGDFGDFGSASGSTPPFVTGTQDSMSDATFE ESSEHFPHFSEPGDDFGEFGDINAVSCQEETIL TKSDLKQTSDNLSEECQLARKSSGTGTEPVAKLK NGQEGEIGHFDSVPNIQDDCNGFQDSDDFADFS SAGPSQVVDWNAFEDEQKDSCSWAAFGDQQATE SHHRKEAWQSHRTDENIDTPGTPKTHSVPSATSK GAVASGHLQESATSVQTALLNRLERIFEACFPS ILVPDAEEEVTSLKHLLETSTLPIKTREALPES GELLDVWTELQDIHDAHGLRYQWGGSHSNKKLLS SLGIDTRNILFTGNKKQPVIVPMYAAGLGMLEP TKEPLKPLSAAEKIASIGQTATMSPDMNTCTSD QFQESLPPVQFDWSSSGLTNPLDGVDPELYELTT SKLEISTSSLKVTDAFARLMSTVEKTSTSTRKP KREEHLSEEAIKVIAGLPDLTFMHAKVLMFPAT LTPSTSSQEKADG*LM*IGQFLLLFLFSIPSLPS KAYLL*LKKKKKKIQVQLICW*AALERYT**CI FIYILKS*IYIRKM*IIGGKHF*RFILFVLLGC IHLCLCEIHWWCPSYKTFEIKKKLKSSLSVKSPS VFSDCIDCPLDFSYYMSNYFCYHK*APKSPI*F FFNFVYDGFQIWLLLTFWGFFNLFNLAYCCLTF CKVLNCSFVIGYGSLSELDWRGLKRLCLFKISMI QRRTKLYECLTMEFTCY*FFCSIVPLFFEDFAQ CKMT*S*IAMV*AVYTVKTMGFKCLGKFLWKKE RHVEEPLTRLMCMPKVF*NFSV*ISF*LIQK*NN LKE

Sequence NM_017657

GCATGATGGGAGAGTGTGTGGAGTGGGCGGGGGGTCTCCGCGGAGGAGGTGGAGGAGGCGGCGGCGGCGGCGGAAGAGGGCGGAGGGTAGTGGGATGGGG GTCCCGCGGCAGCGGTGAAACTCCGGGTGGGCGTCCATGGTGCTGCTGCGCTGACAGGGCTGTGAGCAGCCGGCCTTCCGCTCTCACCAGTTCCGCGTCG GAATAGACGGTCCTTCCCCGGGGAGTCAGTTCCTCCCCGGGCCCCTGAGCCATGCCCATCGCAGCCGCCCCGAAGGAGCCAGGTGTAAATTAATTATTTG AAAGCAACTGAACAATGGAGCCAGACATCATTCGAATGTACTCTTCATCCCCACCACCATTAGACAATGGAGCAGAGGATGATGATGATGATGAATTTGG GGAATTTGGTGGGTTTTCAGAAGTTAGCCCTTCTGGTGTAGGGTTTGTTGATTTCGATACACCAGATTATACTCGTCCCAAGGAAGAGTTTGTACCTTCA AACCATTTTATGCCAATTCATGAATTCTCAGAAAATGTAGATAGCCTTACAAGCTTTAAGTCCATTAAAAATGGTAATGATAAGGACATCACTGCTGAAC TTTCTGCTCCTGTGAAAGGACAGTCTGATGTTTTACTTTCTACCACCAGCAAAGAAATAATTTCATCTGAAATGTTAGCTACTTCCATTGATGGCATGGA AAGACCAGGAAATTTAAATAAAGTAGTGGAGCAGAGACAGAATGTTGGAACACTTGAAAGTTTCTCTCCAGGAGATTTTAGAACTAATATGAATGTTGTT CATCAAAACAAGCAGTTAGAGAGCTGCAATGGTGAAAAGCCTCCTTGTCTGGAGATTCTAACAAATGGGTTTGCAGTGTTGGAAACTGTAAATCCTCAGG GAACAGATGATCTGGACAATGTAGCTGATTCAAAGGGACGGAAGCCTCTTAGCACTCATAGCACTGAGTATAATTTAGACTCTGTACCTAGTCCTGCTGA GGAATTTGCAGATTTTGCCACATTTTCCAAAAAGGAAAGGATACAATTAGAAGAAATAGAATGTGCAGTTTTAAATGATAGAGAAGCACTAACCATTCGG GAAAACAATAAAATTAATAGAGTCAATGAACTGAATTCTGTAAAAGAAGTGGCTTTGGGTAGAAGCTTGGATAACAAAGGAGACACTGATGGAGAGGATC AGGTTTGTGTTTCAGAAATAAGCATAGTGACTAACAGAGGTTTCAGTGTTGAAAAACAAGGCCTTCCAACACTGCAACAGGATGAATTTTTACAGTCAGG TGTTCAGTCAAAGGCTTGGAGTTTGGTAGACTCAGCTGATAATTCAGAAGCCATTAGGAGAGAACAATGTAAAACTGAAGAAAAACTTGACTTACTTACT TCTAAATGTGCTCACCTATGCATGGATTCTGTTAAAACTTCTGATGATGAAGTTGGTTCTCCCAAAGAAGAAAGTAGAAAGTTTACTAATTTCCAAAGCC CAAACATTGACCCCACAGAAGAAAATGATTTGGATGATTCTTTAAGTGTAAAAAATGGTGATAGTAGTAATGACTTTGTGACTTGCAATGATATCAATGA AGATGATTTTGGTGATTTTGGTGACTTTGGCTCTGCCAGTGGCTCAACTCCACCTTTTGTTACTGGTACTCAAGATTCAATGAGTGATGCCACTTTTGAA GAGTCTTCAGAGCACTTTCCACATTTTAGTGAACCAGGTGATGACTTTGGAGAATTTGGGGATATAAATGCTGTTTCTTGCCAAGAGGAGACAATATTAA CAAAGTCAGACCTAAAACAGACTTCTGATAATTTATCAGAAGAATGTCAATTGGCAAGAAAATCTAGTGGAACAGGCACTGAACCTGTTGCAAAACTTAA AAATGGGCAAGAAGGTGAGATTGGACATTTTGATTCTGTGCCAAATATTCAGGATGACTGCAATGGTTTTCAAGACTCTGATGATTTTGCAGACTTCAGT TCAGCTGGTCCTAGCCAAGTTGTAGATTGGAATGCTTTTGAGGATGAACAAAAAGATAGTTGTTCTTGGGCTGCTTTTGGAGACCAGCAGGCTACTGAAT CTCATCATCGAAAGGAAGCCTGGCAGTCACATAGGACAGATGAAAATATTGATACTCCAGGAACCCCCAAAACGCACAGTGTACCTTCAGCAACTTCCAA AGGAGCAGTTGCTAGTGGCCATTTACAGGAATCAGCCACTTCAGTTCAGACAGCTTTATTAAACCGCCTGGAGCGAATTTTCGAAGCATGTTTTCCTTCC ATACTTGTCCCTGATGCTGAAGAGGAAGTTACTTCCCTGAAGCACTTGCTGGAAACAAGCACTTTGCCAATAAAAACGAGAGAGGCCTTACCTGAAAGTG GGGAATTGCTAGATGTGTGGACTGAGCTACAGGATATCCATGATGCACATGGCTTGAGATACCAGTGGGGCGGCTCCCATAGCAACAAGAAGCTTTTGTC CTCCTTGGGAATAGACACCCGAAACATTCTCTTCACGGGCAATAAGAAGCAGCCTGTTATAGTGCCCATGTATGCAGCAGGATTGGGTATGTTAGAGCCC ACCAAGGAACCACTGAAACCACTTTCTGCTGCAGAAAAAATAGCTTCCATCGGTCAGACAGCCACCATGTCACCAGATATGAACACATGTACATCTGATC AGTTCCAGGAGTCTCTACCACCCGTCCAGTTTGACTGGAGTAGCAGTGGCCTTACTAACCCTTTAGATGGTGTGGATCCGGAGTTGTATGAGTTAACAAC TTCTAAGCTGGAAATCTCCACCTCAAGCCTCAAAGTGACTGATGCATTTGCAAGACTCATGTCTACAGTAGAGAAGACAAGCACATCTACCAGTAGGAAA CCGAAAAGAGAAGAGCACCTAAGTGAAGAAGCTATCAAGGTGATCGCTGGCCTTCCTGACTTAACATTCATGCATGCCAAGGTGTTGATGTTCCCAGCCA CGTTAACACCTTCCACAAGCTCTCAAGAAAAAGCAGACGGATAACTGATGTGAATTGGACAGTTTCTATTGCTTTTCCTTTTTTCCATCCCTTCCCTACC ATCAAAAGCATACCTGCTCTAATTAAAAAAAAAAAAAAAAAAAATTCAAGTTCAGCTGATTTGTTGGTAAGCCGCACTAGAAAGGTATACATAGTAATGT ATATTTATTTACATACTGAAGTCCTAAATTTATATTAGAAAAATGTAAATAATCGGGGGTAAACATTTTTGAAGATTTATTCTTTTTGTGTTGCTGGGGT GTATACATTTATGTCTTTGTGAAATACACTGGTGGTGTCCTTCTTACAAAACTTTTGAAATAAAAAAAAAACTCAAATCTTCACTGTCTGTGAAATCCCC TTCAGTCTTTTCAGATTGCATTGACTGTCCTCTTGATTTTTCATATTACATGTCAAATTACTTTTGCTATCATAAATAAGCTCCAAAGTCCCCCATTTAA TTTTTTTTTAATTTTGTGTATGATGGGTTTCAGATCTGGCTTTTGTTAACATTTTGGGGCTTTTTTAATCTTTTCAATCTGGCGTATTGCTGTTTGACCT TTTGCAAGGTACTTAATTGCTCTTTTGTTATAGGGTATGGATCATTGTCAGAACTTGATTGGAGGGGTTTAAAGAGATTGTGTCTGTTTAAAATCAGTAT GATTCAGAGAAGGACCAAATTATATGAATGTCTTACAATGGAATTTACTTGTTACTGATTTTTTTGTTCTATTGTACCACTATTTTTTGAGGATTTTGCA CAGTGTAAAATGACATAATCATAGATTGCTATGGTTTAGGCTGTATATACAGTGAAAACTATGGGTTTTAAATGTTTGGGGAAATTCCTATGGAAAAAAG AGAGACATGTAGAAGAACCTCTAACAAGGTTAATGTGCATGCCCAAGGTCTTTTGAAATTTCAGTGTGTAAATTTCCTTTTAGCTTATACAAAAATAAAA TAATTTAAAAGAAA

refseq_AFTPH.F1 (forward primer)
refseq_AFTPH.R1 (reverse primer)
Single exon skipping

Frame 0

A*WESVWSGRGVSAEEVEEAAAAAEEGGG*WDG GPAAAVKLRVGVHGAAALTGL*AAGLPLSPVPRR NRRSFPGESVPPRAPEPCPSQPPRRSQV*INYL KATEQWSQTSFECTLHPHHH*TMEQRMMMMMNL GNLVGFQKLALLV*GLLISIHQIILVPRKSLYLQ TILCQFMNSQKM*IALQALSPLKMVMIRTSLLN FLLL*KDSLMFYFLPPAKK*FHLKC*LLPLMAW KDQEI*IK*WSRDRMLEHLKVSLQEILELI*MLF IKTSS*RAAMVKSLLVWRF*QMGLQCWKL*ILR EQMIWTM*LIQRDGSLLALIALSII*TLYLVLL RNLQILPHFPKRKGYN*KK*NVQF*MIEKH*PFG KTIKLIESMN*IL*KKWLWVEAWITKETLMERI RFVFQK*A**LTEVSVLKNKAFQHCNRMNFYSQ VFSQRLGVW*TQLIIQKPLGENNVKLKKNLTYLL LNVLTYAWILLKLLMMKLVLPKKKVESLLISKA QTLTPQKKMIWMIL*V*KMVIVVMTL*LAMISM KMILVILVTLALPVAQLHLLLLVLKIQ*VMPLLK SLQSTFHILVNQVMTLENLGI*MLFLAKRRQY* QSQT*NRLLIIYQKNVNWQENLVEQALNLLQNL KMGKKVRLDILILCQIFRMTAMVFKTLMILQTSV QLVLAKL*IGMLLRMNKKIVVLGLLLETSRLLN LIIERKPGSHIGQMKILILQEPPKRTVYLQQLP KEQLLVAIYRNQPLQFRQLY*TAWSEFSKHVFLP YLSLMLKRKLLP*STCWKQALCQ*KRERPYLKV GNC*MCGLSYRISMMHMA*DTSGAAPIATRSFC PPWE*TPETFSSRAIRSSLL*CPCMQQDWVC*SP PRNH*NHFLLQKK*LPSVRQPPCHQI*THVHLI SSRSLYHPSSLTGVAVALLTL*MVWIRSCMS*Q LLSWKSPPQASK*LMHLQDSCLQ*RRQAHLPVGN RKEKST*VKKLSR*SLAFLT*HSCMPRC*CSQP R*HLPQALKKKQTDN*CELDSFYCFSFFPSLPY HQKHTCSN*KKKKKKFKFS*FVGKPH*KGIHSNV YLFTY*SPKFILEKCK*SGVNIFEDLFFLCCWG VYIYVFVKYTGGVLLTKLLK*KKNSNLHCL*NP LQSFQIALTVLLIFHITCQITFAIINKLQSPPFN FFLILCMMGFRSGFC*HFGAFLIFSIWRIAV*P FARYLIALLL*GMDHCQNLIGGV*RDCVCLKSV *FREGPNYMNVLQWNLLVTDFFVLLYHYFLRILH SVK*HNHRLLWFRLYIQ*KLWVLNVWGNSYGKK RDM*KNL*QG*CACPRSFEISVCKFPFSLYKNK II*KK

Frame 1

HDGRVCGVGGGSPRRRWRRRRRRRKRAEGSGMG VPRQR*NSGWASMVLLR*QGCEQPAFRSHQFRV GIDGPSPGSQFLPGPLSHAHRSRPEGARCKLII* KQLNNGARHHSNVLFIPTTIRQWSRG*****IW GIWWVFRS*PFWCRVC*FRYTRLYSSQGRVCTF KPFYANS*ILRKCR*PYKL*VH*KW***GHHC*T FCSCERTV*CFTFYHQQRNNFI*NVSYFH*WHG KTRKFK*SSGAETECWNT*KFLSRRF*N*YECC SSKQAVRELQW*KASLSGDSNKWVCSVGNCKSSG NR*SGQCS*FKGTEAS*HS*H*V*FRLCT*SC* GICRFCHIFQKGKDTIRRNRMCSFK**RSTNHS GKQ*N**SQ*TEFCKRSGFG*KLG*QRRH*WRGS GLCFRNKHSD*QRFQC*KTRPSNTATG*IFTVR CSVKGLEFGRLS**FRSH*ERTM*N*RKT*LTY F*MCSPMHGFC*NF***SWFSQRRK*KVY*FPKP KH*PHRRK*FG*FFKCKKW*****LCDLQ*YQ* R*FW*FW*LWLCQWLNSTFCYWYSRFNE*CHF* RVFRALSTF**TR**LWRIWGYKCCFLPRGDNIN KVRPKTDF**FIRRMSIGKKI*WNRH*TCCKT* KWARR*DWTF*FCAKYSG*LQWFSRL**FCRLQ FSWS*PSCRLECF*G*TKR*LFLGCFWRPAGY*I SSSKGSLAVT*DR*KY*YSRNPQNAQCTFSNFQ RSSC*WPFTGISHFSSDSFIKPPGANFRSMFSF HTCP*C*RGSYFPEALAGNKHFANKNERGLT*KW GIARCVD*ATGYP*CTWLEIPVGRLP*QQEAFV LLGNRHPKHSLHGQ*EAACYSAHVCSRIGYVRA HQGTTETTFCCRKNSFHRSDSHHVTRYEHMYI*S VPGVSTTRPV*LE*QWPY*PFRWCGSGVV*VNN F*AGNLHLKPQSD*CICKTHVYSREDKHIYQ*E TEKRRAPK*RSYQGDRWPS*LNIHACQGVDVPSH VNTFHKLSRKSRRITDVNWTVSIAFPFFHPFPT IKSIPALIKKKKKKNSSSADLLVSRTRKVYIVM YIYLHTEVLNLY*KNVNNRG*TFLKIYSFCVAGV YTFMSL*NTLVVSFLQNF*NKKKTQIFTVCEIP FSLFRLH*LSS*FFILHVKLLLLS*ISSKVPHL IFF*FCV*WVSDLAFVNILGLF*SFQSGVLLFDL LQGT*LLFCYRVWIIVRT*LEGFKEIVSV*NQY DSEKDQII*MSYNGIYLLLIFLFYCTTIF*GFC TV*NDIIIDCYGLGCIYSENYGF*MFGEIPMEKR ETCRRTSNKVNVHAQGLLKFQCVNFLLAYTKIK *FKR

Frame 2

MMGECVEWAGGLRGGGGGGGGGGGRGRRVVGWG SRGSGETPGGRPWCCCADRAVSSRPSALTSSAS E*TVLPRGVSSSPGP*AMPIAAAPKEPGVN*LF ESN*TMEPDIIRMYSSSPPPLDNGAEDDDDDEFG EFGGFSEVSPSGVGFVDFDTPDYTRPKEEFVPS NHFMPIHEFSENVDSLTSFKSIKNGNDKDITAE LSAPVKGQSDVLLSTTSKEIISSEMLATSIDGME RPGNLNKVVEQRQNVGTLESFSPGDFRTNMNVV HQNKQLESCNGEKPPCLEILTNGFAVLETVNPQ GTDDLDNVADSKGRKPLSTHSTEYNLDSVPSPAE EFADFATFSKKERIQLEEIECAVLNDREALTIR ENNKINRVNELNSVKEVALGRSLDNKGDTDGED QVCVSEISIVTNRGFSVEKQGLPTLQQDEFLQSG VQSKAWSLVDSADNSEAIRREQCKTEEKLDLLT SKCAHLCMDSVKTSDDEVGSPKEESRKFTNFQS PNIDPTEENDLDDSLSVKNGDSSNDFVTCNDINE DDFGDFGDFGSASGSTPPFVTGTQDSMSDATFE ESSEHFPHFSEPGDDFGEFGDINAVSCQEETIL TKSDLKQTSDNLSEECQLARKSSGTGTEPVAKLK NGQEGEIGHFDSVPNIQDDCNGFQDSDDFADFS SAGPSQVVDWNAFEDEQKDSCSWAAFGDQQATE SHHRKEAWQSHRTDENIDTPGTPKTHSVPSATSK GAVASGHLQESATSVQTALLNRLERIFEACFPS ILVPDAEEEVTSLKHLLETSTLPIKTREALPES GELLDVWTELQDIHDAHGLRYQWGGSHSNKKLLS SLGIDTRNILFTGNKKQPVIVPMYAAGLGMLEP TKEPLKPLSAAEKIASIGQTATMSPDMNTCTSD QFQESLPPVQFDWSSSGLTNPLDGVDPELYELTT SKLEISTSSLKVTDAFARLMSTVEKTSTSTSRK PKREEHLSEEAIKVIAGLPDLTFMHAKVLMFPA TLTPSTSSQEKADG*LM*IGQFLLLFLFSIPSLP SKAYLL*LKKKKKKIQVQLICW*AALERYT**C IFIYILKS*IYIRKM*IIGGKHF*RFILFVLLG CIHLCLCEIHWWCPSYKTFEIKKKLKSSLSVKSP SVFSDCIDCPLDFSYYMSNYFCYHK*APKSPI* FFFNFVYDGFQIWLLLTFWGFFNLFNLAYCCLT FCKVLNCSFVIGYGSLSELDWRGLKRLCLFKISM IQRRTKLYECLTMEFTCY*FFCSIVPLFFEDFA QCKMT*S*IAMV*AVYTVKTMGFKCLGKFLWKK ERHVEEPLTRLMCMPKVF*NFSV*ISF*LIQK*N NLKE

Sequence NM_203437

GCATGATGGGAGAGTGTGTGGAGTGGGCGGGGGGTCTCCGCGGAGGAGGTGGAGGAGGCGGCGGCGGCGGCGGAAGAGGGCGGAGGGTAGTGGGATGGGG GTCCCGCGGCAGCGGTGAAACTCCGGGTGGGCGTCCATGGTGCTGCTGCGCTGACAGGGCTGTGAGCAGCCGGCCTTCCGCTCTCACCAGTTCCGCGTCG GAATAGACGGTCCTTCCCCGGGGAGTCAGTTCCTCCCCGGGCCCCTGAGCCATGCCCATCGCAGCCGCCCCGAAGGAGCCAGGTGTAAATTAATTATTTG AAAGCAACTGAACAATGGAGCCAGACATCATTCGAATGTACTCTTCATCCCCACCACCATTAGACAATGGAGCAGAGGATGATGATGATGATGAATTTGG GGAATTTGGTGGGTTTTCAGAAGTTAGCCCTTCTGGTGTAGGGTTTGTTGATTTCGATACACCAGATTATACTCGTCCCAAGGAAGAGTTTGTACCTTCA AACCATTTTATGCCAATTCATGAATTCTCAGAAAATGTAGATAGCCTTACAAGCTTTAAGTCCATTAAAAATGGTAATGATAAGGACATCACTGCTGAAC TTTCTGCTCCTGTGAAAGGACAGTCTGATGTTTTACTTTCTACCACCAGCAAAGAAATAATTTCATCTGAAATGTTAGCTACTTCCATTGATGGCATGGA AAGACCAGGAAATTTAAATAAAGTAGTGGAGCAGAGACAGAATGTTGGAACACTTGAAAGTTTCTCTCCAGGAGATTTTAGAACTAATATGAATGTTGTT CATCAAAACAAGCAGTTAGAGAGCTGCAATGGTGAAAAGCCTCCTTGTCTGGAGATTCTAACAAATGGGTTTGCAGTGTTGGAAACTGTAAATCCTCAGG GAACAGATGATCTGGACAATGTAGCTGATTCAAAGGGACGGAAGCCTCTTAGCACTCATAGCACTGAGTATAATTTAGACTCTGTACCTAGTCCTGCTGA GGAATTTGCAGATTTTGCCACATTTTCCAAAAAGGAAAGGATACAATTAGAAGAAATAGAATGTGCAGTTTTAAATGATAGAGAAGCACTAACCATTCGG GAAAACAATAAAATTAATAGAGTCAATGAACTGAATTCTGTAAAAGAAGTGGCTTTGGGTAGAAGCTTGGATAACAAAGGAGACACTGATGGAGAGGATC AGGTTTGTGTTTCAGAAATAAGCATAGTGACTAACAGAGGTTTCAGTGTTGAAAAACAAGGCCTTCCAACACTGCAACAGGATGAATTTTTACAGTCAGG TGTTCAGTCAAAGGCTTGGAGTTTGGTAGACTCAGCTGATAATTCAGAAGCCATTAGGAGAGAACAATGTAAAACTGAAGAAAAACTTGACTTACTTACT TCTAAATGTGCTCACCTATGCATGGATTCTGTTAAAACTTCTGATGATGAAGTTGGTTCTCCCAAAGAAGAAAGTAGAAAGTTTACTAATTTCCAAAGCC CAAACATTGACCCCACAGAAGAAAATGATTTGGATGATTCTTTAAGTGTAAAAAATGGTGATAGTAGTAATGACTTTGTGACTTGCAATGATATCAATGA AGATGATTTTGGTGATTTTGGTGACTTTGGCTCTGCCAGTGGCTCAACTCCACCTTTTGTTACTGGTACTCAAGATTCAATGAGTGATGCCACTTTTGAA GAGTCTTCAGAGCACTTTCCACATTTTAGTGAACCAGGTGATGACTTTGGAGAATTTGGGGATATAAATGCTGTTTCTTGCCAAGAGGAGACAATATTAA CAAAGTCAGACCTAAAACAGACTTCTGATAATTTATCAGAAGAATGTCAATTGGCAAGAAAATCTAGTGGAACAGGCACTGAACCTGTTGCAAAACTTAA AAATGGGCAAGAAGGTGAGATTGGACATTTTGATTCTGTGCCAAATATTCAGGATGACTGCAATGGTTTTCAAGACTCTGATGATTTTGCAGACTTCAGT TCAGCTGGTCCTAGCCAAGTTGTAGATTGGAATGCTTTTGAGGATGAACAAAAAGATAGTTGTTCTTGGGCTGCTTTTGGAGACCAGCAGGCTACTGAAT CTCATCATCGAAAGGAAGCCTGGCAGTCACATAGGACAGATGAAAATATTGATACTCCAGGAACCCCCAAAACGCACAGTGTACCTTCAGCAACTTCCAA AGGAGCAGTTGCTAGTGGCCATTTACAGGAATCAGCCACTTCAGTTCAGACAGCTTTATTAAACCGCCTGGAGCGAATTTTCGAAGCATGTTTTCCTTCC ATACTTGTCCCTGATGCTGAAGAGGAAGTTACTTCCCTGAAGCACTTGCTGGAAACAAGCACTTTGCCAATAAAAACGAGAGAGGCCTTACCTGAAAGTG GGGAATTGCTAGATGTGTGGACTGAGCTACAGGATATCCATGATGCACATGGCTTGAGATACCAGTGGGGCGGCTCCCATAGCAACAAGAAGCTTTTGTC CTCCTTGGGAATAGACACCCGAAACATTCTCTTCACGGGCAATAAGAAGCAGCCTGTTATAGTGCCCATGTATGCAGCAGGATTGGGTATGTTAGAGCCC ACCAAGGAACCACTGAAACCACTTTCTGCTGCAGAAAAAATAGCTTCCATCGGTCAGACAGCCACCATGTCACCAGATATGAACACATGTACATCTGATC AGTTCCAGGAGTCTCTACCACCCGTCCAGTTTGACTGGAGTAGCAGTGGCCTTACTAACCCTTTAGATGCTAGTGGAGGTTCCACTCTTCTGAACCTTGA TTTCTTTGGGCCCGTGGATGACAGTAGCTCTAGCAGCAGCACCACAATCCCAGGTGTGGATCCGGAGTTGTATGAGTTAACAACTTCTAAGCTGGAAATC TCCACCTCAAGCCTCAAAGTGACTGATGCATTTGCAAGACTCATGTCTACAGTAGAGAAGACAAGCACATCTACCAGGAAACCGAAAAGAGAAGAGCACC TAAGTGAAGAAGCTATCAAGGTGATCGCTGGCCTTCCTGACTTAACATTCATGCATGCCAAGGTGTTGATGTTCCCAGCCACGTTAACACCTTCCACAAG CTCTCAAGAAAAAGCAGACGGATAACTGATGTGAATTGGACAGTTTCTATTGCTTTTCCTTTTTTCCATCCCTTCCCTACCATCAAAAGCATACCTGCTC TAATTAAAAAAAAAAAAAAAAAAAATTCAAGTTCAGCTGATTTGTTGGTAAGCCGCACTAGAAAGGTATACATAGTAATGTATATTTATTTACATACTGA AGTCCTAAATTTATATTAGAAAAATGTAAATAATCGGGGGTAAACATTTTTGAAGATTTATTCTTTTTGTGTTGCTGGGGTGTATACATTTATGTCTTTG TGAAATACACTGGTGGTGTCCTTCTTACAAAACTTTTGAAATAAAAAAAAAACTCAAATCTTCACTGTCTGTGAAATCCCCTTCAGTCTTTTCAGATTGC ATTGACTGTCCTCTTGATTTTTCATATTACATGTCAAATTACTTTTGCTATCATAAATAAGCTCCAAAGTCCCCCATTTAATTTTTTTTTAATTTTGTGT ATGATGGGTTTCAGATCTGGCTTTTGTTAACATTTTGGGGCTTTTTTAATCTTTTCAATCTGGCGTATTGCTGTTTGACCTTTTGCAAGGTACTTAATTG CTCTTTTGTTATAGGGTATGGATCATTGTCAGAACTTGATTGGAGGGGTTTAAAGAGATTGTGTCTGTTTAAAATCAGTATGATTCAGAGAAGGACCAAA TTATATGAATGTCTTACAATGGAATTTACTTGTTACTGATTTTTTTGTTCTATTGTACCACTATTTTTTGAGGATTTTGCACAGTGTAAAATGACATAAT CATAGATTGCTATGGTTTAGGCTGTATATACAGTGAAAACTATGGGTTTTAAATGTTTGGGGAAATTCCTATGGAAAAAAGAGAGACATGTAGAAGAACC TCTAACAAGGTTAATGTGCATGCCCAAGGTCTTTTGAAATTTCAGTGTGTAAATTTCCTTTTAGCTTATACAAAAATAAAATAATTTAAAAGAAA

refseq_AFTPH.F1 (forward primer)
refseq_AFTPH.R1 (reverse primer)
Single exon skipping

Frame 0

A*WESVWSGRGVSAEEVEEAAAAAEEGGG*WDG GPAAAVKLRVGVHGAAALTGL*AAGLPLSPVPRR NRRSFPGESVPPRAPEPCPSQPPRRSQV*INYL KATEQWSQTSFECTLHPHHH*TMEQRMMMMMNL GNLVGFQKLALLV*GLLISIHQIILVPRKSLYLQ TILCQFMNSQKM*IALQALSPLKMVMIRTSLLN FLLL*KDSLMFYFLPPAKK*FHLKC*LLPLMAW KDQEI*IK*WSRDRMLEHLKVSLQEILELI*MLF IKTSS*RAAMVKSLLVWRF*QMGLQCWKL*ILR EQMIWTM*LIQRDGSLLALIALSII*TLYLVLL RNLQILPHFPKRKGYN*KK*NVQF*MIEKH*PFG KTIKLIESMN*IL*KKWLWVEAWITKETLMERI RFVFQK*A**LTEVSVLKNKAFQHCNRMNFYSQ VFSQRLGVW*TQLIIQKPLGENNVKLKKNLTYLL LNVLTYAWILLKLLMMKLVLPKKKVESLLISKA QTLTPQKKMIWMIL*V*KMVIVVMTL*LAMISM KMILVILVTLALPVAQLHLLLLVLKIQ*VMPLLK SLQSTFHILVNQVMTLENLGI*MLFLAKRRQY* QSQT*NRLLIIYQKNVNWQENLVEQALNLLQNL KMGKKVRLDILILCQIFRMTAMVFKTLMILQTSV QLVLAKL*IGMLLRMNKKIVVLGLLLETSRLLN LIIERKPGSHIGQMKILILQEPPKRTVYLQQLP KEQLLVAIYRNQPLQFRQLY*TAWSEFSKHVFLP YLSLMLKRKLLP*STCWKQALCQ*KRERPYLKV GNC*MCGLSYRISMMHMA*DTSGAAPIATRSFC PPWE*TPETFSSRAIRSSLL*CPCMQQDWVC*SP PRNH*NHFLLQKK*LPSVRQPPCHQI*THVHLI SSRSLYHPSSLTGVAVALLTL*MLVEVPLF*TL ISLGPWMTVALAAAPQSQVWIRSCMS*QLLSWKS PPQASK*LMHLQDSCLQ*RRQAHLPGNRKEKST *VKKLSR*SLAFLT*HSCMPRC*CSQPR*HLPQ ALKKKQTDN*CELDSFYCFSFFPSLPYHQKHTCS N*KKKKKKFKFS*FVGKPH*KGIHSNVYLFTY* SPKFILEKCK*SGVNIFEDLFFLCCWGVYIYVF VKYTGGVLLTKLLK*KKNSNLHCL*NPLQSFQIA LTVLLIFHITCQITFAIINKLQSPPFNFFLILC MMGFRSGFC*HFGAFLIFSIWRIAV*PFARYLI ALLL*GMDHCQNLIGGV*RDCVCLKSV*FREGPN YMNVLQWNLLVTDFFVLLYHYFLRILHSVK*HN HRLLWFRLYIQ*KLWVLNVWGNSYGKKRDM*KN L*QG*CACPRSFEISVCKFPFSLYKNKII*KK

Frame 1

HDGRVCGVGGGSPRRRWRRRRRRRKRAEGSGMG VPRQR*NSGWASMVLLR*QGCEQPAFRSHQFRV GIDGPSPGSQFLPGPLSHAHRSRPEGARCKLII* KQLNNGARHHSNVLFIPTTIRQWSRG*****IW GIWWVFRS*PFWCRVC*FRYTRLYSSQGRVCTF KPFYANS*ILRKCR*PYKL*VH*KW***GHHC*T FCSCERTV*CFTFYHQQRNNFI*NVSYFH*WHG KTRKFK*SSGAETECWNT*KFLSRRF*N*YECC SSKQAVRELQW*KASLSGDSNKWVCSVGNCKSSG NR*SGQCS*FKGTEAS*HS*H*V*FRLCT*SC* GICRFCHIFQKGKDTIRRNRMCSFK**RSTNHS GKQ*N**SQ*TEFCKRSGFG*KLG*QRRH*WRGS GLCFRNKHSD*QRFQC*KTRPSNTATG*IFTVR CSVKGLEFGRLS**FRSH*ERTM*N*RKT*LTY F*MCSPMHGFC*NF***SWFSQRRK*KVY*FPKP KH*PHRRK*FG*FFKCKKW*****LCDLQ*YQ* R*FW*FW*LWLCQWLNSTFCYWYSRFNE*CHF* RVFRALSTF**TR**LWRIWGYKCCFLPRGDNIN KVRPKTDF**FIRRMSIGKKI*WNRH*TCCKT* KWARR*DWTF*FCAKYSG*LQWFSRL**FCRLQ FSWS*PSCRLECF*G*TKR*LFLGCFWRPAGY*I SSSKGSLAVT*DR*KY*YSRNPQNAQCTFSNFQ RSSC*WPFTGISHFSSDSFIKPPGANFRSMFSF HTCP*C*RGSYFPEALAGNKHFANKNERGLT*KW GIARCVD*ATGYP*CTWLEIPVGRLP*QQEAFV LLGNRHPKHSLHGQ*EAACYSAHVCSRIGYVRA HQGTTETTFCCRKNSFHRSDSHHVTRYEHMYI*S VPGVSTTRPV*LE*QWPY*PFRC*WRFHSSEP* FLWARG*Q*L*QQHHNPRCGSGVV*VNNF*AGN LHLKPQSD*CICKTHVYSREDKHIYQETEKRRAP K*RSYQGDRWPS*LNIHACQGVDVPSHVNTFHK LSRKSRRITDVNWTVSIAFPFFHPFPTIKSIPA LIKKKKKKNSSSADLLVSRTRKVYIVMYIYLHTE VLNLY*KNVNNRG*TFLKIYSFCVAGVYTFMSL *NTLVVSFLQNF*NKKKTQIFTVCEIPFSLFRL H*LSS*FFILHVKLLLLS*ISSKVPHLIFF*FCV *WVSDLAFVNILGLF*SFQSGVLLFDLLQGT*L LFCYRVWIIVRT*LEGFKEIVSV*NQYDSEKDQ II*MSYNGIYLLLIFLFYCTTIF*GFCTV*NDII IDCYGLGCIYSENYGF*MFGEIPMEKRETCRRT SNKVNVHAQGLLKFQCVNFLLAYTKIK*FKR

Frame 2

MMGECVEWAGGLRGGGGGGGGGGGRGRRVVGWG SRGSGETPGGRPWCCCADRAVSSRPSALTSSAS E*TVLPRGVSSSPGP*AMPIAAAPKEPGVN*LF ESN*TMEPDIIRMYSSSPPPLDNGAEDDDDDEFG EFGGFSEVSPSGVGFVDFDTPDYTRPKEEFVPS NHFMPIHEFSENVDSLTSFKSIKNGNDKDITAE LSAPVKGQSDVLLSTTSKEIISSEMLATSIDGME RPGNLNKVVEQRQNVGTLESFSPGDFRTNMNVV HQNKQLESCNGEKPPCLEILTNGFAVLETVNPQ GTDDLDNVADSKGRKPLSTHSTEYNLDSVPSPAE EFADFATFSKKERIQLEEIECAVLNDREALTIR ENNKINRVNELNSVKEVALGRSLDNKGDTDGED QVCVSEISIVTNRGFSVEKQGLPTLQQDEFLQSG VQSKAWSLVDSADNSEAIRREQCKTEEKLDLLT SKCAHLCMDSVKTSDDEVGSPKEESRKFTNFQS PNIDPTEENDLDDSLSVKNGDSSNDFVTCNDINE DDFGDFGDFGSASGSTPPFVTGTQDSMSDATFE ESSEHFPHFSEPGDDFGEFGDINAVSCQEETIL TKSDLKQTSDNLSEECQLARKSSGTGTEPVAKLK NGQEGEIGHFDSVPNIQDDCNGFQDSDDFADFS SAGPSQVVDWNAFEDEQKDSCSWAAFGDQQATE SHHRKEAWQSHRTDENIDTPGTPKTHSVPSATSK GAVASGHLQESATSVQTALLNRLERIFEACFPS ILVPDAEEEVTSLKHLLETSTLPIKTREALPES GELLDVWTELQDIHDAHGLRYQWGGSHSNKKLLS SLGIDTRNILFTGNKKQPVIVPMYAAGLGMLEP TKEPLKPLSAAEKIASIGQTATMSPDMNTCTSD QFQESLPPVQFDWSSSGLTNPLDASGGSTLLNLD FFGPVDDSSSSSSTTIPGVDPELYELTTSKLEI STSSLKVTDAFARLMSTVEKTSTSTRKPKREEH LSEEAIKVIAGLPDLTFMHAKVLMFPATLTPSTS SQEKADG*LM*IGQFLLLFLFSIPSLPSKAYLL *LKKKKKKIQVQLICW*AALERYT**CIFIYIL KS*IYIRKM*IIGGKHF*RFILFVLLGCIHLCLC EIHWWCPSYKTFEIKKKLKSSLSVKSPSVFSDC IDCPLDFSYYMSNYFCYHK*APKSPI*FFFNFV YDGFQIWLLLTFWGFFNLFNLAYCCLTFCKVLNC SFVIGYGSLSELDWRGLKRLCLFKISMIQRRTK LYECLTMEFTCY*FFCSIVPLFFEDFAQCKMT* S*IAMV*AVYTVKTMGFKCLGKFLWKKERHVEEP LTRLMCMPKVF*NFSV*ISF*LIQK*NNLKE