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Sequences

Sequence NM_001009811

CTCACCCCGGCCGTCCGGCCGCTTCATTGTCACCGGGCCTCGGGGCAGTGTTGGGGGTGGCGGGGCGCCAGGTCGCCGACCCGAGGTTTGGGCGCGACTG GTTCCGCATCCCCTCCCCGCCGGCCGAATCTGCAGGCCCCGCGCGCCAGGCAGGCTTCGCGGCTGCGCCCCCGGCCCGCGCAGGACCTGCCTTGTCCACC ATGAAAGGCACCCGGGCCATCGGCAGCGTCCCGGAGCGCAGCCCAGCAGGTGTGGACCTGAGTCTGACAGGTCTCCCTCCGCCTGTGTCCCGGCGTCCTG GCAGTGCCGCCACCACCAAGCCCATCGTCCGCTCTGTCTCCGTGGTCACAGGCAGCGAGCAGAAGAGGAAGGTGCTGGAGGCCACAGGGCCTGGGGGCTC CCAGGCCATCAACAACCTTAGAAGATCCAACAGCACCACGCAGGTCAGCCAGCCTCGGAGCGGCTCCCCCAGGCCAACGGAGCCCACAGACTTCCTGATG CTCTTCGAGGGCAGCCCCAGTGGGAAAAAGAGGCCTGCCAGCCTGAGCACAGCCCCCAGCGAGAAGGGAGCCACCTGGAACGTCCTGGATGACCAGCCCC GGGGCTTCACCTTGCCATCCAATGCCCGGAGTTCCAGTGCCCTTGACTCACCAGCGGGCCCGCGGAGGAAAGAATGCACCGTGGCCCTGGCCCCCAACTT CACTGCTAACAACAGGAGCAACAAGGGAGCAGTGGGCAACTGCGTCACCACCATGGTGCACAACCGCTACACCCCCTCGGAGAGGGCGCCTCCGCTCAAG AGCTCCAACCAGACTGCCCCCTCCCTCAACAACATCATCAAGGCAGCCACCTGTGAGGGCAGTGAGAGCAGCGGCTTTGGGAAGCTGCCGAAGAATGTCT CCAGTGCCACCCACTCAGCCCGGAACAATACTGGGGGCAGCACGGGCTTGCCCAGGCGGAAGGAGGTGACGGAGGAGGAGGCTGAGAGGTTTATCCACCA GGTGAACCAGGCCACTGTCACCATCCAGCGCTGGTACCGGCACCAGGTGCAGCGGCGCGGAGCAGGAGCTGCCCGCCTGGAGCACTTGCTTCAGGCCAAG CGGGAGGAGCAGCGGCAGCGGTCAGGCGAGGGGACCCTCTTGGACCTGCACCAGCAGAAAGAGGCAGCCAGGAGGAAGGCCCGGGAGGAGAAGGCACGCC AAGCCAGGCGAGCAGCCATTCAGGAGCTGCAACAGAAACGAGCCCTGAGAGCCCAGAAGGCGAGCACTGCCGAGCGTGGGCCACCTGAGAATCCCAGGGA GACCAGAGTGCCAGGAATGCGGCAGCCTGCTCAGGAGCTGTCCCCCACACCAGGCGGCACTGCCCACCAGGCCCTCAAGGCCAACAATACTGGTGGTGGC CTCCCTGCTGCAGGCCCCGGAGACCGCTGCCTGCCCACCTCCGACTCATCCCCAGAACCACAGCAGCCTCCAGAGGACAGGACGCAGGACGTTCTTGCCC AGGATGCAGCTGGGGACAACCTGGAGATGATGGCCCCGAGCAGGGGGAGCGCCAAGTCCAGGGGGCCACTGGAGGAGCTGCTGCACACACTGCAGCTGCT GGAGAAGGAGCCGGACGTGCTGCCCCGCCCCAGGACCCATCACAGGGGCAGATACGCCTGGGCCAGCGAGGAGGATGACGCCAGCTCTCTGACAGCTGAC AACTTGGAGAAATTTGGAAAACTCAGTGCGTTCCCCGAACCTCCTGAGGATGGGACGCTGCTATCGGAGGCCAAGCTACAAAGCATCATGAGCTTCTTGG ACGAGATGGAGAAGTCTGGGCAGGACCAGCTGGACTCCCAGCAGGAGGGGTGGGTGCCGGAGGCGGGGCCGGGGCCCCTGGAGCTGGGGTCCGAGGTGAG CACGTCTGTGATGCGGCTGAAGCTGGAGGTGGAGGAGAAGAAGCAGGCCATGCTGCTGCTGCAGAGAGCGCTGGCGCAGCAGCGAGACCTCACGGCCCGG CGGGTCAAGGAGACAGAGAAGGCGCTGAGCCGGCAGCTGCAGCGGCAGAGGGAGCACTACGAGGCCACCATCCAGCGGCACTTGGCCTTCATTGACCAGC TGATTGAGGACAAGAAGGTCCTGAGTGAAAAGTGCGAGGCTGTGGTGGCCGAGCTGAAGCAGGAGGACCAGAGATGCACCGAGCGTGTGGCCCAGGCACA GGCGCAGCACGAGCTGGAGATTAAAAAACTCAAAGAATTAATGAGCGCCACCGAGAAAGCCCGCCGGGAGAAGTGGATCAGTGAGAAAACCAAGAAGATC AAGGAGGTCACTGTCCGAGGTCTGGAGCCCGAGATCCAGAAGCTGATTGCAAGGCACAAGCAGGAAGTGCGGAGGCTCAAGAGCCTGCACGAGGCGGAGC TGCTGCAGTCGGATGAGCGGGCCTCGCAGCGCTGCCTGCGCCAGGCCGAGGAGCTGCGGGAGCAGCTGGAGCGGGAGAAGGAGGCGCTGGGCCAGCAGGA GCGCGAACGTGCTCGGCAGCGGCAGCGGGCGGAGCTGGAAGAGCTGAGGCAGCAGCTGGAGGAGAGCAGCTCTGCACTGACCCGAGCCCTGAGGGCTGAG TTTGAGAAGGGCAGGGAGGAGCAGGAGCGCCGGCACCAGATGGAGCTGAATACCCTGAAGCAGCAGCTGGAGCTGGAGAGGCAGGCGTGGGAGGCCGGCC GCACCAGGAAGGAGGAGGCGTGGCTGCTGAACCGGGAACAGGAGCTGAGGGAAGAAATCCGGAAAGGCCGGGACAAGGAGATTGAGCTGGTCATTCACCG GCTGGAGGCCGACATGGCGCTGGCCAAGGAGGAGAGTGAGAAGGCTGCCGAGAGCCGCATCAAGCGCTTACGGGACAAGTACGAGGCCGAGCTCTCCGAG CTGGAGCAGTCGGAGCGGAAGCTTCAGGAGCGGTGCTCGGAGCTGAAGGGCCAGCTTGGGGAGGCCGAGGGCGAGAATCTGCGTCTGCAGGGCCTTGTGC GGCAGAAGGAGCGGGCGCTGGAGGATGCGCAGGCGGTGAACGAGCAGCTTTCTAGCGAGCGCAGCAACCTGGCCCAGGTGATCCGCCAGGAGTTCGAGGA CCGGCTGGCAGCCTCTGAGGAGGAGACGCGGCAGGCCAAGGCCGAGCTGGCCACGCTGCAGGCCCGCCAGCAGCTGGAGCTGGAGGAGGTGCACCGGAGG GTGAAGACAGCCCTCGCGAGGAAGGAGGAGGCCGTGAGCAGCCTCCGGACACAACATGAGGCTGCGGTGAAGCGGGCCGACCACCTGGAGGAGCTGCTGG AGCAGCACAGGAGGCCCACGCCAAGTACCAAGTGACCAGGGATGCCGGGAACACTGTCGAAGAACGGAAGGCAGAGGACAGAGGCTGGACGTGGGCCCAG AGGCCCACAGGGACGCCCACCTGCCCCCCACAGAGGCTGGTGGTTGAGATGCCCACGGCTAAGCACCTGTGGCTGCATTTTAACAGTAAAGGAGGCCGTT GTTTTCAGCGC

refseq_AZI1.F2 (forward primer)
refseq_AZI1.R2 (reverse primer)
Single exon skipping

Frame 0

LTPAVRPLHCHRASGQCWGWRGARSPTRGLGAT GSASPPRRPNLQAPRARQASRLRPRPAQDLPCPP *KAPGPSAASRSAAQQVWT*V*QVSLRLCPGVL AVPPPPSPSSALSPWSQAASRRGRCWRPQGLGA PRPSTTLEDPTAPRRSASLGAAPPGQRSPQTS*C SSRAAPVGKRGLPA*AQPPARREPPGTSWMTSP GASPCHPMPGVPVPLTHQRARGGKNAPWPWPPT SLLTTGATREQWATASPPWCTTATPPRRGRLRSR APTRLPPPSTTSSRQPPVRAVRAAALGSCRRMS PVPPTQPGTILGAARACPGGRR*RRRRLRGLST R*TRPLSPSSAGTGTRCSGAEQELPAWSTCFRPS GRSSGSGQARGPSWTCTSRKRQPGGRPGRRRHA KPGEQPFRSCNRNEP*EPRRRALPSVGHLRIPG RPECQECGSLLRSCPPHQAALPTRPSRPTILVVA SLLQAPETAACPPPTHPQNHSSLQRTGRRTFLP RMQLGTTWR*WPRAGGAPSPGGHWRSCCTHCSC WRRSRTCCPAPGPITGADTPGPARRMTPAL*QLT TWRNLENSVRSPNLLRMGRCYRRPSYKAS*ASW TRWRSLGRTSWTPSRRGGCRRRGRGPWSWGPR* ARL*CG*SWRWRRRSRPCCCCRERWRSSETSRPG GSRRQRRR*AGSCSGRGSTTRPPSSGTWPSLTS *LRTRRS*VKSARLWWPS*SRRTRDAPSVWPRH RRSTSWRLKNSKN**APPRKPAGRSGSVRKPRRS RRSLSEVWSPRSRS*LQGTSRKCGGSRACTRRS CCSRMSGPRSAACARPRSCGSSWSGRRRRWASR SANVLGSGSGRSWKS*GSSWRRAALH*PEP*GLS LRRAGRSRSAGTRWS*IP*SSSWSWRGRRGRPA APGRRRRGC*TGNRS*GKKSGKAGTRRLSWSFT GWRPTWRWPRRRVRRLPRAASSAYGTSTRPSSPS WSSRSGSFRSGARS*RASLGRPRARICVCRALC GRRSGRWRMRRR*TSSFLASAATWPR*SARSSR TGWQPLRRRRGRPRPSWPRCRPASSWSWRRCTGG *RQPSRGRRRP*AASGHNMRLR*SGPTTWRSCW SSTGGPRQVPSDQGCREHCRRTEGRGQRLDVGP EAHRDAHLPPTEAGG*DAHG*APVAAF*Q*RRPL FSA

Frame 1

SPRPSGRFIVTGPRGSVGGGGAPGRRPEVWARL VPHPLPAGRICRPRAPGRLRGCAPGPRRTCLVH HERHPGHRQRPGAQPSRCGPESDRSPSACVPASW QCRHHQAHRPLCLRGHRQRAEEEGAGGHRAWGL PGHQQP*KIQQHHAGQPASERLPQANGAHRLPD ALRGQPQWEKEACQPEHSPQREGSHLERPG*PAP GLHLAIQCPEFQCP*LTSGPAEERMHRGPGPQL HC*QQEQQGSSGQLRHHHGAQPLHPLGEGASAQ ELQPDCPLPQQHHQGSHL*GQ*EQRLWEAAEECL QCHPLSPEQYWGQHGLAQAEGGDGGGG*EVYPP GEPGHCHHPALVPAPGAAARSRSCPPGALASGQ AGGAAAAVRRGDPLGPAPAERGSQEEGPGGEGTP SQASSHSGAATETSPESPEGEHCRAWAT*ESQG DQSARNAAACSGAVPHTRRHCPPGPQGQQYWWW PPCCRPRRPLPAHLRLIPRTTAASRGQDAGRSCP GCSWGQPGDDGPEQGERQVQGATGGAAAHTAAA GEGAGRAAPPQDPSQGQIRLGQRGG*RQLSDS* QLGEIWKTQCVPRTS*GWDAAIGGQATKHHELLG RDGEVWAGPAGLPAGGVGAGGGAGAPGAGVRGE HVCDAAEAGGGGEEAGHAAAAESAGAAARPHGP AGQGDREGAEPAAAAAEGALRGHHPAALGLH*PA D*GQEGPE*KVRGCGGRAEAGGPEMHRACGPGT GAARAGD*KTQRINERHRESPPGEVDQ*ENQED QGGHCPRSGARDPEADCKAQAGSAEAQEPARGGA AAVG*AGLAALPAPGRGAAGAAGAGEGGAGPAG ARTCSAAAAGGAGRAEAAAGGEQLCTDPSPEG* V*EGQGGAGAPAPDGAEYPEAAAGAGEAGVGGRP HQEGGGVAAEPGTGAEGRNPERPGQGD*AGHSP AGGRHGAGQGGE*EGCREPHQALTGQVRGRALR AGAVGAEASGAVLGAEGPAWGGRGRESASAGPCA AEGAGAGGCAGGERAAF*RAQQPGPGDPPGVRG PAGSL*GGDAAGQGRAGHAAGPPAAGAGGGAPE GEDSPREEGGGREQPPDTT*GCGEAGRPPGGAAG AAQEAHAKYQVTRDAGNTVEERKAEDRGWTWAQ RPTGTPTCPPQRLVVEMPTAKHLWLHFNSKGGR CFQR

Frame 2

HPGRPAASLSPGLGAVLGVAGRQVADPRFGRDW FRIPSPPAESAGPARQAGFAAAPPARAGPALST MKGTRAIGSVPERSPAGVDLSLTGLPPPVSRRP GSAATTKPIVRSVSVVTGSEQKRKVLEATGPGGS QAINNLRRSNSTTQVSQPRSGSPRPTEPTDFLM LFEGSPSGKKRPASLSTAPSEKGATWNVLDDQP RGFTLPSNARSSSALDSPAGPRRKECTVALAPNF TANNRSNKGAVGNCVTTMVHNRYTPSERAPPLK SSNQTAPSLNNIIKAATCEGSESSGFGKLPKNV SSATHSARNNTGGSTGLPRRKEVTEEEAERFIHQ VNQATVTIQRWYRHQVQRRGAGAARLEHLLQAK REEQRQRSGEGTLLDLHQQKEAARRKAREEKAR QARRAAIQELQQKRALRAQKASTAERGPPENPRE TRVPGMRQPAQELSPTPGGTAHQALKANNTGGG LPAAGPGDRCLPTSDSSPEPQQPPEDRTQDVLA QDAAGDNLEMMAPSRGSAKSRGPLEELLHTLQLL EKEPDVLPRPRTHHRGRYAWASEEDDASSLTAD NLEKFGKLSAFPEPPEDGTLLSEAKLQSIMSFL DEMEKSGQDQLDSQQEGWVPEAGPGPLELGSEVS TSVMRLKLEVEEKKQAMLLLQRALAQQRDLTAR RVKETEKALSRQLQRQREHYEATIQRHLAFIDQ LIEDKKVLSEKCEAVVAELKQEDQRCTERVAQAQ AQHELEIKKLKELMSATEKARREKWISEKTKKI KEVTVRGLEPEIQKLIARHKQEVRRLKSLHEAE LLQSDERASQRCLRQAEELREQLEREKEALGQQE RERARQRQRAELEELRQQLEESSSALTRALRAE FEKGREEQERRHQMELNTLKQQLELERQAWEAG RTRKEEAWLLNREQELREEIRKGRDKEIELVIHR LEADMALAKEESEKAAESRIKRLRDKYEAELSE LEQSERKLQERCSELKGQLGEAEGENLRLQGLV RQKERALEDAQAVNEQLSSERSNLAQVIRQEFED RLAASEEETRQAKAELATLQARQQLELEEVHRR VKTALARKEEAVSSLRTQHEAAVKRADHLEELL EQHRRPTPSTK*PGMPGTLSKNGRQRTEAGRGPR GPQGRPPAPHRGWWLRCPRLSTCGCILTVKEAV VFS

Sequence NM_014984

CTCACCCCGGCCGTCCGGCCGCTTCATTGTCACCGGGCCTCGGGGCAGTGTTGGGGGTGGCGGGGCGCCAGGTCGCCGACCCGAGGTTTGGGCGCGACTG GTTCCGCATCCCCTCCCCGCCGGCCGAATCTGCAGGCCCCGCGCGCCAGGCAGGCTTCGCGGCTGCGCCCCCGGCCCGCGCAGGACCTGCCTTGTCCACC ATGAAAGGCACCCGGGCCATCGGCAGCGTCCCGGAGCGCAGCCCAGCAGGTGTGGACCTGAGTCTGACAGGTCTCCCTCCGCCTGTGTCCCGGCGTCCTG GCAGTGCCGCCACCACCAAGCCCATCGTCCGCTCTGTCTCCGTGGTCACAGGCAGCGAGCAGAAGAGGAAGGTGCTGGAGGCCACAGGGCCTGGGGGCTC CCAGGCCATCAACAACCTTAGAAGATCCAACAGCACCACGCAGGTCAGCCAGCCTCGGAGCGGCTCCCCCAGGCCAACGGAGCCCACAGACTTCCTGATG CTCTTCGAGGGCAGCCCCAGTGGGAAAAAGAGGCCTGCCAGCCTGAGCACAGCCCCCAGCGAGAAGGGAGCCACCTGGAACGTCCTGGATGACCAGCCCC GGGGCTTCACCTTGCCATCCAATGCCCGGAGTTCCAGTGCCCTTGACTCACCAGCGGGCCCGCGGAGGAAAGAATGCACCGTGGCCCTGGCCCCCAACTT CACTGCTAACAACAGGAGCAACAAGGGAGCAGTGGGCAACTGCGTCACCACCATGGTGCACAACCGCTACACCCCCTCGGAGAGGGCGCCTCCGCTCAAG AGCTCCAACCAGACTGCCCCCTCCCTCAACAACATCATCAAGGCAGCCACCTGTGAGGGCAGTGAGAGCAGCGGCTTTGGGAAGCTGCCGAAGAATGTCT CCAGTGCCACCCACTCAGCCCGGAACAATACTGGGGGCAGCACGGGCTTGCCCAGGCGGAAGGAGGTGACGGAGGAGGAGGCTGAGAGGTTTATCCACCA GGTGAACCAGGCCACTGTCACCATCCAGCGCTGGTACCGGCACCAGGTGCAGCGGCGCGGAGCAGGAGCTGCCCGCCTGGAGCACTTGCTTCAGGCCAAG CGGGAGGAGCAGCGGCAGCGGTCAGGCGAGGGGACCCTCTTGGACCTGCACCAGCAGAAAGAGGCAGCCAGGAGGAAGGCCCGGGAGGAGAAGGCACGCC AAGCCAGGCGAGCAGCCATTCAGGAGCTGCAACAGAAACGAGCCCTGAGAGCCCAGAAGGCGAGCACTGCCGAGCGTGGGCCACCTGAGAATCCCAGGGA GACCAGAGTGCCAGGAATGCGGCAGCCTGCTCAGGAGCTGTCCCCCACACCAGGCGGCACTGCCCACCAGGCCCTCAAGGCCAACAATACTGGTGGTGGC CTCCCTGCTGCAGGCCCCGGAGACCGCTGCCTGCCCACCTCCGACTCATCCCCAGAACCACAGCAGCCTCCAGAGGACAGGACGCAGGACGTTCTTGCCC AGGATGCAGCTGGGGACAACCTGGAGATGATGGCCCCGAGCAGGGGGAGCGCCAAGTCCAGGGGGCCACTGGAGGAGCTGCTGCACACACTGCAGCTGCT GGAGAAGGAGCCGGACGTGCTGCCCCGCCCCAGGACCCATCACAGGGGCAGATACGCCTGGGCCAGCGAGGAGGATGACGCCAGCTCTCTGACAGCTGAC AACTTGGAGAAATTTGGAAAACTCAGTGCGTTCCCCGAACCTCCTGAGGATGGGACGCTGCTATCGGAGGCCAAGCTACAAAGCATCATGAGCTTCTTGG ACGAGATGGAGAAGTCTGGGCAGGACCAGCTGGACTCCCAGCAGGAGGGGTGGGTGCCGGAGGCGGGGCCGGGGCCCCTGGAGCTGGGGTCCGAGGTGAG CACGTCTGTGATGCGGCTGAAGCTGGAGGTGGAGGAGAAGAAGCAGGCCATGCTGCTGCTGCAGAGAGCGCTGGCGCAGCAGCGAGACCTCACGGCCCGG CGGGTCAAGGAGACAGAGAAGGCGCTGAGCCGGCAGCTGCAGCGGCAGAGGGAGCACTACGAGGCCACCATCCAGCGGCACTTGGCCTTCATTGACCAGC TGATTGAGGACAAGAAGGTCCTGAGTGAAAAGTGCGAGGCTGTGGTGGCCGAGCTGAAGCAGGAGGACCAGAGATGCACCGAGCGTGTGGCCCAGGCACA GGCGCAGCACGAGCTGGAGATTAAAAAACTCAAAGAATTAATGAGCGCCACCGAGAAAGCCCGCCGGGAGAAGTGGATCAGTGAGAAAACCAAGAAGATC AAGGAGGTCACTGTCCGAGGTCTGGAGCCCGAGATCCAGAAGCTGATTGCAAGGCACAAGCAGGAAGTGCGGAGGCTCAAGAGCCTGCACGAGGCGGAGC TGCTGCAGTCGGATGAGCGGGCCTCGCAGCGCTGCCTGCGCCAGGCCGAGGAGCTGCGGGAGCAGCTGGAGCGGGAGAAGGAGGCGCTGGGCCAGCAGGA GCGCGAACGTGCTCGGCAGCGGTTCCAGCAGCACCTGGAGCAGGAGCAGTGGGCGCTGCAGCAGCAACGGCAGCGGCTGTACAGTGAGGTGGCTGAGGAG AGGGAGCGGCTGGGCCAGCAGGCAGCCAGGCAGCGGGCGGAGCTGGAAGAGCTGAGGCAGCAGCTGGAGGAGAGCAGCTCTGCACTGACCCGAGCCCTGA GGGCTGAGTTTGAGAAGGGCAGGGAGGAGCAGGAGCGCCGGCACCAGATGGAGCTGAATACCCTGAAGCAGCAGCTGGAGCTGGAGAGGCAGGCGTGGGA GGCCGGCCGCACCAGGAAGGAGGAGGCGTGGCTGCTGAACCGGGAACAGGAGCTGAGGGAAGAAATCCGGAAAGGCCGGGACAAGGAGATTGAGCTGGTC ATTCACCGGCTGGAGGCCGACATGGCGCTGGCCAAGGAGGAGAGTGAGAAGGCTGCCGAGAGCCGCATCAAGCGCTTACGGGACAAGTACGAGGCCGAGC TCTCCGAGCTGGAGCAGTCGGAGCGGAAGCTTCAGGAGCGGTGCTCGGAGCTGAAGGGCCAGCTTGGGGAGGCCGAGGGCGAGAATCTGCGTCTGCAGGG CCTTGTGCGGCAGAAGGAGCGGGCGCTGGAGGATGCGCAGGCGGTGAACGAGCAGCTTTCTAGCGAGCGCAGCAACCTGGCCCAGGTGATCCGCCAGGAG TTCGAGGACCGGCTGGCAGCCTCTGAGGAGGAGACGCGGCAGGCCAAGGCCGAGCTGGCCACGCTGCAGGCCCGCCAGCAGCTGGAGCTGGAGGAGGTGC ACCGGAGGGTGAAGACAGCCCTCGCGAGGAAGGAGGAGGCCGTGAGCAGCCTCCGGACACAACATGAGGCTGCGGTGAAGCGGGCCGACCACCTGGAGGA GCTGCTGGAGCAGCACAGGAGGCCCACGCCAAGTACCAAGTGACCAGGGATGCCGGGAACACTGTCGAAGAACGGAAGGCAGAGGACAGAGGCTGGACGT GGGCCCAGAGGCCCACAGGGACGCCCACCTGCCCCCCACAGAGGCTGGTGGTTGAGATGCCCACGGCTAAGCACCTGTGGCTGCATTTTAACAGTAAAGG AGGCCGTTGTTTTCAGCGC

refseq_AZI1.F2 (forward primer)
refseq_AZI1.R2 (reverse primer)
Single exon skipping

Frame 0

LTPAVRPLHCHRASGQCWGWRGARSPTRGLGAT GSASPPRRPNLQAPRARQASRLRPRPAQDLPCPP *KAPGPSAASRSAAQQVWT*V*QVSLRLCPGVL AVPPPPSPSSALSPWSQAASRRGRCWRPQGLGA PRPSTTLEDPTAPRRSASLGAAPPGQRSPQTS*C SSRAAPVGKRGLPA*AQPPARREPPGTSWMTSP GASPCHPMPGVPVPLTHQRARGGKNAPWPWPPT SLLTTGATREQWATASPPWCTTATPPRRGRLRSR APTRLPPPSTTSSRQPPVRAVRAAALGSCRRMS PVPPTQPGTILGAARACPGGRR*RRRRLRGLST R*TRPLSPSSAGTGTRCSGAEQELPAWSTCFRPS GRSSGSGQARGPSWTCTSRKRQPGGRPGRRRHA KPGEQPFRSCNRNEP*EPRRRALPSVGHLRIPG RPECQECGSLLRSCPPHQAALPTRPSRPTILVVA SLLQAPETAACPPPTHPQNHSSLQRTGRRTFLP RMQLGTTWR*WPRAGGAPSPGGHWRSCCTHCSC WRRSRTCCPAPGPITGADTPGPARRMTPAL*QLT TWRNLENSVRSPNLLRMGRCYRRPSYKAS*ASW TRWRSLGRTSWTPSRRGGCRRRGRGPWSWGPR* ARL*CG*SWRWRRRSRPCCCCRERWRSSETSRPG GSRRQRRR*AGSCSGRGSTTRPPSSGTWPSLTS *LRTRRS*VKSARLWWPS*SRRTRDAPSVWPRH RRSTSWRLKNSKN**APPRKPAGRSGSVRKPRRS RRSLSEVWSPRSRS*LQGTSRKCGGSRACTRRS CCSRMSGPRSAACARPRSCGSSWSGRRRRWASR SANVLGSGSSSTWSRSSGRCSSNGSGCTVRWLRR GSGWASRQPGSGRSWKS*GSSWRRAALH*PEP* GLSLRRAGRSRSAGTRWS*IP*SSSWSWRGRRG RPAAPGRRRRGC*TGNRS*GKKSGKAGTRRLSWS FTGWRPTWRWPRRRVRRLPRAASSAYGTSTRPS SPSWSSRSGSFRSGARS*RASLGRPRARICVCR ALCGRRSGRWRMRRR*TSSFLASAATWPR*SARS SRTGWQPLRRRRGRPRPSWPRCRPASSWSWRRC TGG*RQPSRGRRRP*AASGHNMRLR*SGPTTWR SCWSSTGGPRQVPSDQGCREHCRRTEGRGQRLDV GPEAHRDAHLPPTEAGG*DAHG*APVAAF*Q*R RPLFSA

Frame 1

SPRPSGRFIVTGPRGSVGGGGAPGRRPEVWARL VPHPLPAGRICRPRAPGRLRGCAPGPRRTCLVH HERHPGHRQRPGAQPSRCGPESDRSPSACVPASW QCRHHQAHRPLCLRGHRQRAEEEGAGGHRAWGL PGHQQP*KIQQHHAGQPASERLPQANGAHRLPD ALRGQPQWEKEACQPEHSPQREGSHLERPG*PAP GLHLAIQCPEFQCP*LTSGPAEERMHRGPGPQL HC*QQEQQGSSGQLRHHHGAQPLHPLGEGASAQ ELQPDCPLPQQHHQGSHL*GQ*EQRLWEAAEECL QCHPLSPEQYWGQHGLAQAEGGDGGGG*EVYPP GEPGHCHHPALVPAPGAAARSRSCPPGALASGQ AGGAAAAVRRGDPLGPAPAERGSQEEGPGGEGTP SQASSHSGAATETSPESPEGEHCRAWAT*ESQG DQSARNAAACSGAVPHTRRHCPPGPQGQQYWWW PPCCRPRRPLPAHLRLIPRTTAASRGQDAGRSCP GCSWGQPGDDGPEQGERQVQGATGGAAAHTAAA GEGAGRAAPPQDPSQGQIRLGQRGG*RQLSDS* QLGEIWKTQCVPRTS*GWDAAIGGQATKHHELLG RDGEVWAGPAGLPAGGVGAGGGAGAPGAGVRGE HVCDAAEAGGGGEEAGHAAAAESAGAAARPHGP AGQGDREGAEPAAAAAEGALRGHHPAALGLH*PA D*GQEGPE*KVRGCGGRAEAGGPEMHRACGPGT GAARAGD*KTQRINERHRESPPGEVDQ*ENQED QGGHCPRSGARDPEADCKAQAGSAEAQEPARGGA AAVG*AGLAALPAPGRGAAGAAGAGEGGAGPAG ARTCSAAVPAAPGAGAVGAAAATAAAVQ*GG*G EGAAGPAGSQAAGGAGRAEAAAGGEQLCTDPSPE G*V*EGQGGAGAPAPDGAEYPEAAAGAGEAGVG GRPHQEGGGVAAEPGTGAEGRNPERPGQGD*AG HSPAGGRHGAGQGGE*EGCREPHQALTGQVRGRA LRAGAVGAEASGAVLGAEGPAWGGRGRESASAG PCAAEGAGAGGCAGGERAAF*RAQQPGPGDPPG VRGPAGSL*GGDAAGQGRAGHAAGPPAAGAGGGA PEGEDSPREEGGGREQPPDTT*GCGEAGRPPGG AAGAAQEAHAKYQVTRDAGNTVEERKAEDRGWT WAQRPTGTPTCPPQRLVVEMPTAKHLWLHFNSKG GRCFQR

Frame 2

HPGRPAASLSPGLGAVLGVAGRQVADPRFGRDW FRIPSPPAESAGPARQAGFAAAPPARAGPALST MKGTRAIGSVPERSPAGVDLSLTGLPPPVSRRP GSAATTKPIVRSVSVVTGSEQKRKVLEATGPGGS QAINNLRRSNSTTQVSQPRSGSPRPTEPTDFLM LFEGSPSGKKRPASLSTAPSEKGATWNVLDDQP RGFTLPSNARSSSALDSPAGPRRKECTVALAPNF TANNRSNKGAVGNCVTTMVHNRYTPSERAPPLK SSNQTAPSLNNIIKAATCEGSESSGFGKLPKNV SSATHSARNNTGGSTGLPRRKEVTEEEAERFIHQ VNQATVTIQRWYRHQVQRRGAGAARLEHLLQAK REEQRQRSGEGTLLDLHQQKEAARRKAREEKAR QARRAAIQELQQKRALRAQKASTAERGPPENPRE TRVPGMRQPAQELSPTPGGTAHQALKANNTGGG LPAAGPGDRCLPTSDSSPEPQQPPEDRTQDVLA QDAAGDNLEMMAPSRGSAKSRGPLEELLHTLQLL EKEPDVLPRPRTHHRGRYAWASEEDDASSLTAD NLEKFGKLSAFPEPPEDGTLLSEAKLQSIMSFL DEMEKSGQDQLDSQQEGWVPEAGPGPLELGSEVS TSVMRLKLEVEEKKQAMLLLQRALAQQRDLTAR RVKETEKALSRQLQRQREHYEATIQRHLAFIDQ LIEDKKVLSEKCEAVVAELKQEDQRCTERVAQAQ AQHELEIKKLKELMSATEKARREKWISEKTKKI KEVTVRGLEPEIQKLIARHKQEVRRLKSLHEAE LLQSDERASQRCLRQAEELREQLEREKEALGQQE RERARQRFQQHLEQEQWALQQQRQRLYSEVAEE RERLGQQAARQRAELEELRQQLEESSSALTRAL RAEFEKGREEQERRHQMELNTLKQQLELERQAWE AGRTRKEEAWLLNREQELREEIRKGRDKEIELV IHRLEADMALAKEESEKAAESRIKRLRDKYEAE LSELEQSERKLQERCSELKGQLGEAEGENLRLQG LVRQKERALEDAQAVNEQLSSERSNLAQVIRQE FEDRLAASEEETRQAKAELATLQARQQLELEEV HRRVKTALARKEEAVSSLRTQHEAAVKRADHLEE LLEQHRRPTPSTK*PGMPGTLSKNGRQRTEAGR GPRGPQGRPPAPHRGWWLRCPRLSTCGCILTVK EAVVFS