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Sequences

Sequence NM_183359

GGGTTTCGGCCCTTCCAGACCGTCTCTCCTCAGGGTTGGAGACTTCGGGGCCAAGATGGCGACGGGAACGGGCAAACACAAGCTGCTAAGCACTGGCCCC ACAGAGCCATGGTCCATCCGAGAGAAGCTATGTTTAGCATCTTCTGTCATGAGAAGTGGCGATCAAAATTGGGTATCAGTTAGCAGAGCAATCAAGCCCT TTGCAGAACCTGGCCGCCCTCCAGACTGGTTCTCTCAAAAACATTGTGCTTCCCAGTACTCGGAGCTTTTAGAGACCACTGAGACACCAAAACGGAAACG AGGTGAAAAGGGAGAAGTGGTGGAAACTGTTGAAGATGTTATTGTTCGGAAATTGACTGCTGAGCGAGTTGAAGAACTAAAGAAAGTGATAAAGGAAACC CAGGAGAGATATAGACGGCTAAAGAGAGATGCAGAACTAATTCAAGCTGGACACATGGACAGCAGACTGGATGAGCTTTGCAATGACATTGAAAAAGAAA TTGGAAGAAGAGGAGGCTGAAGTAAAGAGGAAGGCTACAGATGCTGCATACCAGGCTCGTCAAGCAGTAAAAACACCCCCCCGGAGGTTACCCACTGTGA TGGTTCGCTCTCCTATAGATTCTGCCTCCCCAGGAGGTGATTATCCACTTGGGGACTTGACTCCAACCACTATGGAAGAGGCTACCTCTGGGGTAACCCC CGGGACTTTGCCGAGTACCCCAGTCACCTCGTTTCCTGGGATTCCTGACACCCTTCCTCCAGGCTCTGCACCCTTAGAAGCCCCCATGACCCCAGTAACA GATGATTCACCCCAGAAAAAGATGCTTGGACAGAAAGCAACTCCACCCCCCTCCCCTCTGCTGTCAGAGCTCTTGAAGAAGGGCAGCCTCCTGCCTACTA GCCCCAGACTGGTCAATGAGAGTGAAATGGCTGTGGCTTCTGGCCACCTGAACAGTACAGGTGTCCTCCTGGAGGTAGGCGGGGTCCTTCCCATGATACA TGGTGGGGAGATACAGCAAACACCCAATACTGTTGCAGCCTCCCCTGCTGCATCAGAGTCTGTGTCCCAAGCTACCATTGTCATGATGCCTGCGCTGCCA GCACCATCCTCTGCTCCGGCTGTCTCCACTACTGAAAGTGTAGCTCCAGTGAGTCAACCCGACAACTGTGTTCCCATGGAGGCTGTGGGGGATCCACATA CTGTGACTGTTTCCATGGACAGCAGTGAAATATCCATGATCATCAATTCTATCAAAGAAGAGTGTTTTCGATCAGGGGTAGCAGAGGCTCCTGTTGGATC AAAGGCTCCCAGCATAGATGGGAAGGAAGAATTAGATCTGGCTGAGAAGATGGATATTGCTGTGTCTTACACAGGTGAAGAGCTGGATTTTGAGACTGTT GGAGACATCATTGCCATCATTGAGGACAAGGTAGATGATCATCCTGAAGTGCTGGATGTGGCAGCAGTGGAAGCAGCACTGTCATTTTGTGAAGAAAATG ATGATCCTCAGTCCCTGCCTGGCCCCTGGGAGCATCCTATCCAGCAGGAGCGGGACAAGCCAGTACCTCTCCCTGCACCAGAAATGACGGTCAAGCAAGA GAGACTGGACTTTGAGGAAACGGAAAACAAGGGAATACATGAACTGGTGGACATCAGGGAGCCCAGTGCAGAGATCAAGGTGGAACCTGCAGAACCAGAG CCAGTCATTTCAGGAGCCGAAATAGTAGCTGGAGTTGTTCCAGCCACAAGTATGGAGCCACCAGAACTCAGGAGTCAGGACTTAGATGAGGAACTGGGAA GTACTGCAGCTGGAGAGATTGTTGAAGCAGATGTTGCCATTGGGAAAGGCGATGAGACTCCACTTACAAATGTGAAGACAGAGGCATCCCCTGAAAGCAT GTTGTCTCCATCACATGGCTCAAATCCCATTGAAGATCCTTTAGAGGCAGAGACTCAGCACAAGTTTGAAATGTCAGACTCATTGAAAGAAGAATCAGGG ACTATTTTTGGAAGCCAGATAAAGGATGCCCCAGGTGAGGATGAGGAGGAAGATGGTGTCAGTGAAGCGGCCAGCCTAGAGGAGCCTAAGGAAGAGGATC AAGGAGAAGGCTACTTGTCAGAAATGGATAATGAACCTCCTGTGAGCGAGAGTGATGATGGCTTCAGCATACACAATGCTACACTGCAGTCACACACACT GGCAGACTCCATCCCCAGCAGCCCTGCTTCTTCACAGTTCTCTGTCTGTAGTGAGGATCAGGAAGCTATTCAGGCACAGAAAATTTGGAAGAAAGCCATC ATGCTTGTATGGAGAGCTGCAGCTAATCATAGGTATGCCAATGTCTTCCTGCAGCCTGTTACAGATGACATAGCACCTGGCTACCACAGCATTGTGCAGA GGCCTATGGATTTGTCAACTATTAAGAAAAACATAGAAAATGGACTGATCCGAAGCACAGCTGAATTTCAGCGTGACATTATGCTGATGTTTCAGAATGC TGTAATGTACAATAGCTCAGACCATGATGTCTATCACATGGCAGTGGAGATGCAGCGAGATGTCTTGGAACAGATCCAGCAATTCTTGGCCACGCAGTTG ATTATGCAAACATCCGAGTCTGGGATCAGTGCTAAAAGTCTTCGAGGGAGAGATTCTACCCGCAAACAGGATGCTTCAGAGAAGGATGGAGGAACCAGGG GACGCCGCTGTGCCATTGAAGCAGATATGAAGATGAAAAAGTGAAGCCTCAGAGTTACCCTCTTTGAGCCGAACCTAAAATAAAAGTAAACAAGATAGAG CTTGGGCTTGCGGGCCCAGTTCCAGAGGTGGAAGTTACAGAAGAGGAGGTACCTGGGCCACACGACATGAGCTGGAAAATCTCTCTTAGAGAGTTGGAGT AGCACAATTGCCTGTTTTAGGGCAGAAACCATGGGCTATGTTAATGTCCTAATGTGTAGCTAGCAGATCGTAGCTAGTTTGTATTGTCTTGTCAATTGTA CAGACTTTTTAAAAAAAACAACCACCAGTGAAATGTGTGTGTATACAATAAACTGAAAAAAAAAACTA

refseq_BRD8.F2 (forward primer)
refseq_BRD8.R2 (reverse primer)
Single exon skipping

Frame 0

GFRPFQTVSPQGWRLRGQDGDGNGQTQAAKHWP HRAMVHPREAMFSIFCHEKWRSKLGIS*QSNQAL CRTWPPSRLVLSKTLCFPVLGAFRDH*DTKTET R*KGRSGGNC*RCYCSEIDC*AS*RTKESDKGN PGEI*TAKERCRTNSSWTHGQQTG*ALQ*H*KRN WKKRRLK*RGRLQMLHTRLVKQ*KHPPGGYPL* WFALL*ILPPQEVIIHLGT*LQPLWKRLPLG*P PGLCRVPQSPRFLGFLTPFLQALHP*KPP*PQ*Q MIHPRKRCLDRKQLHPPPLCCQSS*RRAASCLL APDWSMRVKWLWLLAT*TVQVSSWR*AGSFP*Y MVGRYSKHPILLQPPLLHQSLCPKLPLS*CLRCQ HHPLLRLSPLLKV*LQ*VNPTTVFPWRLWGIHI L*LFPWTAVKYP*SSILSKKSVFDQG*QRLLLD QRLPA*MGRKN*IWLRRWILLCLTQVKSWILRLL ETSLPSLRTR*MIILKCWMWQQWKQHCHFVKKM MILSPCLAPGSILSSRSGTSQYLSLHQK*RSSK RDWTLRKRKTREYMNWWTSGSPVQRSRWNLQNQS QSFQEPK**LELFQPQVWSHQNSGVRT*MRNWE VLQLERLLKQMLPLGKAMRLHLQM*RQRHPLKA CCLHHMAQIPLKIL*RQRLSTSLKCQTH*KKNQG LFLEAR*RMPQVRMRRKMVSVKRPA*RSLRKRI KEKATCQKWIMNLL*ARVMMASAYTMLHCSHTH WQTPSPAALLLHSSLSVVRIRKLFRHRKFGRKPS CLYGELQLIIGMPMSSCSLLQMT*HLATTALCR GLWICQLLRKT*KMD*SEAQLNFSVTLC*CFRM L*CTIAQTMMSITWQWRCSEMSWNRSSNSWPRS* LCKHPSLGSVLKVFEGEILPANRMLQRRMEEPG DAAVPLKQI*R*KSEASELPSLSRT*NKSKQDR AWACGPSSRGGSYRRGGTWATRHELENLS*RVGV AQLPVLGQKPWAMLMS*CVASRS*LVCIVLSIV QTF*KKQPPVKCVCIQ*TEKKN

Frame 1

GFGPSRPSLLRVGDFGAKMATGTGKHKLLSTGP TEPWSIREKLCLASSVMRSGDQNWVSVSRAIKP FAEPGRPPDWFSQKHCASQYSELLETTETPKRKR GEKGEVVETVEDVIVRKLTAERVEELKKVIKET QERYRRLKRDAELIQAGHMDSRLDELCNDIEKE IGRRGG*SKEEGYRCCIPGSSSSKNTPPEVTHCD GSLSYRFCLPRR*LSTWGLDSNHYGRGYLWGNP RDFAEYPSHLVSWDS*HPSSRLCTLRSPHDPSN R*FTPEKDAWTESNSTPLPSAVRALEEGQPPAY* PQTGQ*E*NGCGFWPPEQYRCPPGGRRGPSHDT WWGDTANTQYCCSLPCCIRVCVPSYHCHDACAA STILCSGCLHY*KCSSSESTRQLCSHGGCGGSTY CDCFHGQQ*NIHDHQFYQRRVFSIRGSRGSCWI KGSQHRWEGRIRSG*EDGYCCVLHR*RAGF*DC WRHHCHH*GQGR*SS*SAGCGSSGSSTVIL*RK* *SSVPAWPLGASYPAGAGQASTSPCTRNDGQAR ETGL*GNGKQGNT*TGGHQGAQCRDQGGTCRTR ASHFRSRNSSWSCSSHKYGATRTQESGLR*GTGK YCSWRDC*SRCCHWERR*DSTYKCEDRGIP*KH VVSITWLKSH*RSFRGRDSAQV*NVRLIERRIR DYFWKPDKGCPR*G*GGRWCQ*SGQPRGA*GRGS RRRLLVRNG**TSCERE**WLQHTQCYTAVTHT GRLHPQQPCFFTVLCL**GSGSYSGTENLEESH HACMESCS*S*VCQCLPAACYR*HSTWLPQHCAE AYGFVNY*EKHRKWTDPKHS*ISA*HYADVSEC CNVQ*LRP*CLSHGSGDAARCLGTDPAILGHAV DYANIRVWDQC*KSSRERFYPQTGCFREGWRNQG TPLCH*SRYEDEKVKPQSYPL*AEPKIKVNKIE LGLAGPVPEVEVTEEEVPGPHDMSWKISLRELE *HNCLF*GRNHGLC*CPNV*LADRS*FVLSCQLY RLFKKNNHQ*NVCVYNKLKKKT

Frame 2

VSALPDRLSSGLETSGPRWRRERANTSC*ALAP QSHGPSERSYV*HLLS*EVAIKIGYQLAEQSSP LQNLAALQTGSLKNIVLPSTRSF*RPLRHQNGN EVKREKWWKLLKMLLFGN*LLSELKN*RK**RKP RRDIDG*REMQN*FKLDTWTADWMSFAMTLKKK LEEEEAEVKRKATDAAYQARQAVKTPPRRLPTV MVRSPIDSASPGGDYPLGDLTPTTMEEATSGVTP GTLPSTPVTSFPGIPDTLPPGSAPLEAPMTPVT DDSPQKKMLGQKATPPPSPLLSELLKKGSLLPT SPRLVNESEMAVASGHLNSTGVLLEVGGVLPMIH GGEIQQTPNTVAASPAASESVSQATIVMMPALP APSSAPAVSTTESVAPVSQPDNCVPMEAVGDPH TVTVSMDSSEISMIINSIKEECFRSGVAEAPVGS KAPSIDGKEELDLAEKMDIAVSYTGEELDFETV GDIIAIIEDKVDDHPEVLDVAAVEAALSFCEEN DDPQSLPGPWEHPIQQERDKPVPLPAPEMTVKQE RLDFEETENKGIHELVDIREPSAEIKVEPAEPE PVISGAEIVAGVVPATSMEPPELRSQDLDEELG STAAGEIVEADVAIGKGDETPLTNVKTEASPESM LSPSHGSNPIEDPLEAETQHKFEMSDSLKEESG TIFGSQIKDAPGEDEEEDGVSEAASLEEPKEED QGEGYLSEMDNEPPVSESDDGFSIHNATLQSHTL ADSIPSSPASSQFSVCSEDQEAIQAQKIWKKAI MLVWRAAANHRYANVFLQPVTDDIAPGYHSIVQ RPMDLSTIKKNIENGLIRSTAEFQRDIMLMFQNA VMYNSSDHDVYHMAVEMQRDVLEQIQQFLATQL IMQTSESGISAKSLRGRDSTRKQDASEKDGGTR GRRCAIEADMKMKK*SLRVTLFEPNLK*K*TR*S LGLRAQFQRWKLQKRRYLGHTT*AGKSLLESWS STIACFRAETMGYVNVLMCS*QIVASLYCLVNC TDFLKKTTTSEMCVYTIN*KKKL

Sequence NM_006696

GGGTTTCGGCCCTTCCAGACCGTCTCTCCTCAGGGTTGGAGACTTCGGGGCCAAGATGGCGACGGGAACGGGCAAACACAAGCTGCTAAGCACTGGCCCC ACAGAGCCATGGTCCATCCGAGAGAAGCTATGTTTAGCATCTTCTGTCATGAGAAGTGGCGATCAAAATTGGGTATCAGTTAGCAGAGCAATCAAGCCCT TTGCAGAACCTGGCCGCCCTCCAGACTGGTTCTCTCAAAAACATTGTGCTTCCCAGTACTCGGAGCTTTTAGAGACCACTGAGACACCAAAACGGAAACG AGGTGAAAAGGGAGAAGTGGTGGAAACTGTTGAAGATGTTATTGTTCGGAAATTGACTGCTGAGCGAGTTGAAGAACTAAAGAAAGTGATAAAGGAAACC CAGGAGAGATATAGACGGCTAAAGAGAGATGCAGAACTAATTCAAGCTGGACACATGGACAGCAGACTGGATGAGCTTTGCAATGACATTGCAACGAAAA AGAAATTGGAAGAAGAGGAGGCTGAAGTAAAGAGGAAGGCTACAGATGCTGCATACCAGGCTCGTCAAGCAGTAAAAACACCCCCCCGGAGGTTACCCAC TGTGATGGTTCGCTCTCCTATAGATTCTGCCTCCCCAGGAGGTGATTATCCACTTGGGGACTTGACTCCAACCACTATGGAAGAGGCTACCTCTGGGGTA ACCCCCGGGACTTTGCCGAGTACCCCAGTCACCTCGTTTCCTGGGATTCCTGACACCCTTCCTCCAGGCTCTGCACCCTTAGAAGCCCCCATGACCCCAG TAACAGATGATTCACCCCAGAAAAAGATGCTTGGACAGAAAGCAACTCCACCCCCCTCCCCTCTGCTGTCAGAGCTCTTGAAGAAGGGCAGCCTCCTGCC TACTAGCCCCAGACTGGTCAATGAGAGTGAAATGGCTGTGGCTTCTGGCCACCTGAACAGTACAGGTGTCCTCCTGGAGGTAGGCGGGGTCCTTCCCATG ATACATGGTGGGGAGATACAGCAAACACCCAATACTGTTGCAGCCTCCCCTGCTGCATCAGGTGCTCCCACTCTTTCCCGGCTTTTAGAAGCTGGTCCTA CACAGTTCACCACACCTCTTGCTTCCTTCACTACTGTTGCCAGTGAGCCTCCAGTTAAACTTGTGCCACCCCCTGTAGAGTCTGTGTCCCAAGCTACCAT TGTCATGATGCCTGCGCTGCCAGCACCATCCTCTGCTCCGGCTGTCTCCACTACTGAAAGTGTAGCTCCAGTGAGTCAACCCGACAACTGTGTTCCCATG GAGGCTGTGGGGGATCCACATACTGTGACTGTTTCCATGGACAGCAGTGAAATATCCATGATCATCAATTCTATCAAAGAAGAGTGTTTTCGATCAGGGG TAGCAGAGGCTCCTGTTGGATCAAAGGCTCCCAGCATAGATGGGAAGGAAGAATTAGATCTGGCTGAGAAGATGGATATTGCTGTGTCTTACACAGGTGA AGAGCTGGATTTTGAGACTGTTGGAGACATCATTGCCATCATTGAGGACAAGGTAGATGATCATCCTGAAGTGCTGGATGTGGCAGCAGTGGAAGCAGCA CTGTCATTTTGTGAAGAAAATGATGATCCTCAGTCCCTGCCTGGCCCCTGGGAGCATCCTATCCAGCAGGAGCGGGACAAGCCAGTACCTCTCCCTGCAC CAGAAATGACGGTCAAGCAAGAGAGACTGGACTTTGAGGAAACGGAAAACAAGGGAATACATGAACTGGTGGACATCAGGGAGCCCAGTGCAGAGATCAA GGTGGAACCTGCAGAACCAGAGCCAGTCATTTCAGGAGCCGAAATAGTAGCTGGAGTTGTTCCAGCCACAAGTATGGAGCCACCAGAACTCAGGAGTCAG GACTTAGATGAGGAACTGGGAAGTACTGCAGCTGGAGAGATTGTTGAAGCAGATGTTGCCATTGGGAAAGGCGATGAGACTCCACTTACAAATGTGAAGA CAGAGGCATCCCCTGAAAGCATGTTGTCTCCATCACATGGCTCAAATCCCATTGAAGATCCTTTAGAGGCAGAGACTCAGCACAAGTTTGAAATGTCAGA CTCATTGAAAGAAGAATCAGGGACTATTTTTGGAAGCCAGATAAAGGATGCCCCAGGTGAGGATGAGGAGGAAGATGGTGTCAGTGAAGCGGCCAGCCTA GAGGAGCCTAAGGAAGAGGATCAAGGAGAAGGCTACTTGTCAGAAATGGATAATGAACCTCCTGTGAGCGAGAGTGATGATGGCTTCAGCATACACAATG CTACACTGCAGTCACACACACTGGCAGACTCCATCCCCAGCAGCCCTGCTTCTTCACAGTTCTCTGTCTGTAGTGAGGATCAGGAAGCTATTCAGGCACA GAAAATTTGGAAGAAAGCCATCATGCTTGTATGGAGAGCTGCAGCTAATCATAGGTATGCCAATGTCTTCCTGCAGCCTGTTACAGATGACATAGCACCT GGCTACCACAGCATTGTGCAGAGGCCTATGGATTTGTCAACTATTAAGAAAAACATAGAAAATGGACTGATCCGAAGCACAGCTGAATTTCAGCGTGACA TTATGCTGATGTTTCAGAATGCTGTAATGTACAATAGCTCAGACCATGATGTCTATCACATGGCAGTGGAGATGCAGCGAGATGTCTTGGAACAGATCCA GCAATTCTTGGCCACGCAGTTGATTATGCAAACATCCGAGTCTGGGATCAGTGCTAAAAGTCTTCGAGGGAGAGATTCTACCCGCAAACAGGATGCTTCA GAGAAGGACAGTGTCCCAATGGGCTCTCCTGCCTTCCTTCTCTCTCTCTTTGATGGAGGAACCAGGGGACGCCGCTGTGCCATTGAAGCAGATATGAAGA TGAAAAAGTGAAGCCTCAGAGTTACCCTCTTTGAGCCGAACCTAAAATAAAAGTAAACAAGATAGAGCTTGGGCTTGCGGGCCCAGTTCCAGAGGTGGAA GTTACAGAAGAGGAGGTACCTGGGCCACACGACATGAGCTGGAAAATCTCTCTTAGAGAGTTGGAGTAGCACAATTGCCTGTTTTAGGGCAGAAACCATG GGCTATGTTAATGTCCTAATGTGTAGCTAGCAGATCGTAGCTAGTTTGTATTGTCTTGTCAATTGTACAGACTTTTTAAAAAAAACAACCACCAGTGAAA TGTGTGTGTATACAATAAACTGAAAAAAAAAACTA

refseq_BRD8.F2 (forward primer)
refseq_BRD8.R2 (reverse primer)
Single exon skipping

Frame 0

GFRPFQTVSPQGWRLRGQDGDGNGQTQAAKHWP HRAMVHPREAMFSIFCHEKWRSKLGIS*QSNQAL CRTWPPSRLVLSKTLCFPVLGAFRDH*DTKTET R*KGRSGGNC*RCYCSEIDC*AS*RTKESDKGN PGEI*TAKERCRTNSSWTHGQQTG*ALQ*HCNEK EIGRRGG*SKEEGYRCCIPGSSSSKNTPPEVTH CDGSLSYRFCLPRR*LSTWGLDSNHYGRGYLWG NPRDFAEYPSHLVSWDS*HPSSRLCTLRSPHDPS NR*FTPEKDAWTESNSTPLPSAVRALEEGQPPA Y*PQTGQ*E*NGCGFWPPEQYRCPPGGRRGPSH DTWWGDTANTQYCCSLPCCIRCSHSFPAFRSWSY TVHHTSCFLHYCCQ*ASS*TCATPCRVCVPSYH CHDACAASTILCSGCLHY*KCSSSESTRQLCSH GGCGGSTYCDCFHGQQ*NIHDHQFYQRRVFSIRG SRGSCWIKGSQHRWEGRIRSG*EDGYCCVLHR* RAGF*DCWRHHCHH*GQGR*SS*SAGCGSSGSS TVIL*RK**SSVPAWPLGASYPAGAGQASTSPCT RNDGQARETGL*GNGKQGNT*TGGHQGAQCRDQ GGTCRTRASHFRSRNSSWSCSSHKYGATRTQES GLR*GTGKYCSWRDC*SRCCHWERR*DSTYKCED RGIP*KHVVSITWLKSH*RSFRGRDSAQV*NVR LIERRIRDYFWKPDKGCPR*G*GGRWCQ*SGQP RGA*GRGSRRRLLVRNG**TSCERE**WLQHTQC YTAVTHTGRLHPQQPCFFTVLCL**GSGSYSGT ENLEESHHACMESCS*S*VCQCLPAACYR*HST WLPQHCAEAYGFVNY*EKHRKWTDPKHS*ISA*H YADVSECCNVQ*LRP*CLSHGSGDAARCLGTDP AILGHAVDYANIRVWDQC*KSSRERFYPQTGCF REGQCPNGLSCLPSLSL*WRNQGTPLCH*SRYED EKVKPQSYPL*AEPKIKVNKIELGLAGPVPEVE VTEEEVPGPHDMSWKISLRELE*HNCLF*GRNH GLC*CPNV*LADRS*FVLSCQLYRLFKKNNHQ*N VCVYNKLKKKT

Frame 1

GFGPSRPSLLRVGDFGAKMATGTGKHKLLSTGP TEPWSIREKLCLASSVMRSGDQNWVSVSRAIKP FAEPGRPPDWFSQKHCASQYSELLETTETPKRKR GEKGEVVETVEDVIVRKLTAERVEELKKVIKET QERYRRLKRDAELIQAGHMDSRLDELCNDIATK KKLEEEEAEVKRKATDAAYQARQAVKTPPRRLPT VMVRSPIDSASPGGDYPLGDLTPTTMEEATSGV TPGTLPSTPVTSFPGIPDTLPPGSAPLEAPMTP VTDDSPQKKMLGQKATPPPSPLLSELLKKGSLLP TSPRLVNESEMAVASGHLNSTGVLLEVGGVLPM IHGGEIQQTPNTVAASPAASGAPTLSRLLEAGP TQFTTPLASFTTVASEPPVKLVPPPVESVSQATI VMMPALPAPSSAPAVSTTESVAPVSQPDNCVPM EAVGDPHTVTVSMDSSEISMIINSIKEECFRSG VAEAPVGSKAPSIDGKEELDLAEKMDIAVSYTGE ELDFETVGDIIAIIEDKVDDHPEVLDVAAVEAA LSFCEENDDPQSLPGPWEHPIQQERDKPVPLPA PEMTVKQERLDFEETENKGIHELVDIREPSAEIK VEPAEPEPVISGAEIVAGVVPATSMEPPELRSQ DLDEELGSTAAGEIVEADVAIGKGDETPLTNVK TEASPESMLSPSHGSNPIEDPLEAETQHKFEMSD SLKEESGTIFGSQIKDAPGEDEEEDGVSEAASL EEPKEEDQGEGYLSEMDNEPPVSESDDGFSIHN ATLQSHTLADSIPSSPASSQFSVCSEDQEAIQAQ KIWKKAIMLVWRAAANHRYANVFLQPVTDDIAP GYHSIVQRPMDLSTIKKNIENGLIRSTAEFQRD IMLMFQNAVMYNSSDHDVYHMAVEMQRDVLEQIQ QFLATQLIMQTSESGISAKSLRGRDSTRKQDAS EKDSVPMGSPAFLLSLFDGGTRGRRCAIEADMK MKK*SLRVTLFEPNLK*K*TR*SLGLRAQFQRWK LQKRRYLGHTT*AGKSLLESWSSTIACFRAETM GYVNVLMCS*QIVASLYCLVNCTDFLKKTTTSE MCVYTIN*KKKL

Frame 2

VSALPDRLSSGLETSGPRWRRERANTSC*ALAP QSHGPSERSYV*HLLS*EVAIKIGYQLAEQSSP LQNLAALQTGSLKNIVLPSTRSF*RPLRHQNGN EVKREKWWKLLKMLLFGN*LLSELKN*RK**RKP RRDIDG*REMQN*FKLDTWTADWMSFAMTLQRK RNWKKRRLK*RGRLQMLHTRLVKQ*KHPPGGYP L*WFALL*ILPPQEVIIHLGT*LQPLWKRLPLG* PPGLCRVPQSPRFLGFLTPFLQALHP*KPP*PQ *QMIHPRKRCLDRKQLHPPPLCCQSS*RRAASC LLAPDWSMRVKWLWLLAT*TVQVSSWR*AGSFP* YMVGRYSKHPILLQPPLLHQVLPLFPGF*KLVL HSSPHLLLPSLLLPVSLQLNLCHPL*SLCPKLP LS*CLRCQHHPLLRLSPLLKV*LQ*VNPTTVFPW RLWGIHIL*LFPWTAVKYP*SSILSKKSVFDQG *QRLLLDQRLPA*MGRKN*IWLRRWILLCLTQV KSWILRLLETSLPSLRTR*MIILKCWMWQQWKQH CHFVKKMMILSPCLAPGSILSSRSGTSQYLSLH QK*RSSKRDWTLRKRKTREYMNWWTSGSPVQRS RWNLQNQSQSFQEPK**LELFQPQVWSHQNSGVR T*MRNWEVLQLERLLKQMLPLGKAMRLHLQM*R QRHPLKACCLHHMAQIPLKIL*RQRLSTSLKCQ TH*KKNQGLFLEAR*RMPQVRMRRKMVSVKRPA* RSLRKRIKEKATCQKWIMNLL*ARVMMASAYTM LHCSHTHWQTPSPAALLLHSSLSVVRIRKLFRH RKFGRKPSCLYGELQLIIGMPMSSCSLLQMT*HL ATTALCRGLWICQLLRKT*KMD*SEAQLNFSVT LC*CFRML*CTIAQTMMSITWQWRCSEMSWNRS SNSWPRS*LCKHPSLGSVLKVFEGEILPANRMLQ RRTVSQWALLPSFSLSLMEEPGDAAVPLKQI*R *KSEASELPSLSRT*NKSKQDRAWACGPSSRGG SYRRGGTWATRHELENLS*RVGVAQLPVLGQKPW AMLMS*CVASRS*LVCIVLSIVQTF*KKQPPVK CVCIQ*TEKKN