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Sequences

Sequence NM_003939

TAAGAGAGGGCGGGGGGAAGGAAGAGGAGGCGGGATCCGGGCGCTGCGTTGGCTGCGGCCTGGCACCAAAGGGGCGGCCCCGGCGGAGAGCGGACCCAGT
GGCCTCGGCGAT
TATGGACCCGGCCGAGGCGGTGCTGCAAGAGAAGGCACTCAAGTTTATGAATTCCTCAGAGAGAGAAGACTGTAATAATGGCGAACCC
CCTAGGAAGATAATACCAGAGAAGAATTCACTTAGACAGACATACAACAGCTGTGCCAGACTCTGCTTAAACCAAGAAACAGTATGTTTAGCAAGCACTG
CTATGAAGACTGAGAATTGTGTGGCCAAAACAAAACTTGCCAATGGCACTTCCAGTATGATTGTGCCCAAGCAACGGAAACTCTCAGCAAGCTATGAAAA
GGAAAAGGAACTGTGTGTCAAATACTTTGAGCAGTGGTCAGAGTCAGATCAAGTGGAATTTGTGGAACATCTTATATCCCAAATGTGTCATTACCAACAT
GGGCACATAAACTCGTATCTTAAACCTATGTTGCAGAGAGATTTCATAACTGCTCTGCCAGCTCGGGGATTGGATCATATTGCTGAGAACATTCTGTCAT
ACCTGGATGCCAAATCACTATGTGCTGCTGAACTTGTGTGCAAGGAATGGTACCGAGTGACCTCTGATGGCATGCTGTGGAAGAAGCTTATCGAGAGAAT
GGTCAGGACAGATTCTCTGTGGAGAGGCCTGGCAGAACGAAGAGGATGGGGACAGTATTTATTCAAAAACAAACCTCCTGACGGGAATGCTCCTCCCAAC
TCTTTTTATAGAGCACTTTATCCTAAAATTATACAAGACATTGAGACAATAGAATCTAATTGGAGATGTGGAAGACATAGTTTACAGAGAATTCACTGCC
GAAGTGAAACAAGCAAAGGAGTTTACTGTTTACAGTATGATGATCAGAAAATAGTAAGCGGCCTTCGAGACAACACAATCAAGATCTGGGATAAAAACAC
ATTGGAATGCAAGCGAATTCTCACAGGCCATACAGGTTCAGTCCTCTGTCTCCAGTATGATGAGAGAGTGATCATAACAGGATCATCGGATTCCACGGTC
AGAGTGTGGGATGTAAATACAGGTGAAATGCTAAACACGTTGATTCACCATTGTGAAGCAGTTCTGCACTTGCGTTTCAATAATGGCATGATGGTGACCT
GCTCCAAAGATCGTTCCATTGCTGTATGGGATATGGCCTCCCCAACTGACATTACCCTCCGGAGGGTGCTGGTCGGACACCGAGCTGCTGTCAATGTTGT
AGACTTTGATGACAAGTACATTGTTTCTGCATCTGGGGATAGAACTATAAAGGTATGGAACACAAGTACTTGTGAATTTGTAAGGACCTTAAATGGACAC
AAACGAGGCATTGCCTGTTTGCAGTACAGGGACAGGCTGGTAGTGAGTGGCTCATCTGACAACACTATCAGATTATGGGACATAGAATGTGGTGCATGTT
TACGAGTGTTAGAAGGCCATGAGGAATTGGTGCGTTGTATTCGATTTGATAACAAGAGGATAGTCAGTGGGGCCTATGATGGAAAAATTAAAGTGTGGGA
TCTTGTGGCTGCTTTGGACCCCCGTGCTCCTGCAGGGACACTCTGTCTACGGACCCTTGTGGAGCATTCCGGAAGAGTTTTTCGACTACAGTTTGATGAA
TTCCAGATTGTCAGTAGTTCACATGATGACACAATCCTCATCTGGGACTTCCTAAATGATCCAGCTGCCCAAGCTGAACCCCCCCGTTCCCCTTCTCGAA
CATACACCTACATCTCCAGATAAATAACCATACACTGACCTCATACTTGCCCAGGACCCATTAAAGTTGCGGTATTTAACGTATCTGCCAATACCAGGAT
GAGCAACAACAGTAACAATCAAACTACTGCCCAGTTTCCCTGGACTAGCCGAGGAGCAGGGCTTTGAGACTCCTGTTGGGACACAGTTGGTCTGCAGTCG
GCCCAGGACGGTCTACTCAGCACAACTGACTGCTTCAGTGCTGCTATCAGAAGATGTCTTCTATCTTTTGTGAATGATTGGAACTTTTAAACCTCCCCTC
CTCTCCTCCTTTCACCTCTGCACCTAGTTTTTTCCCATTGGTTCCAGACAAAGGTGACTTATAAATATATTTAGTGTTTTGCCAGAATCTCTCTTGCTTT
GCCATTAAGCAGAAGAACTAGTTTCCCTGTATAGCCTGCTGGGAGAGACCCACTTCTAGGGTATGGGGGATGCAGCTTCAAGCCCAGTGCCCAGTGTCTC
CCTGTTAACTGCAGGAATGCCAAGCACCTGGCCAGAGCAGCCCAGCCCCAATATGCTTAGGAGGAGACAGAGTTCCCTCTGTATAGCCTCTGGGACAAGA
AAAAGAAAACACAAGAATGTATACACTGGAAGATTTGGGCCTCCTGCCTGCCTTCTCTTTGTTTCTGTTCCTCTTCCCATCTACTCCCCTACGCCCCTTC
AACCTTTTTTCTCTGTCTGCTTCACCTGAGAAGAAAGTGTACGAAGAGAGTGTCCTCCTCTCACATGAGCCAGATCAGCCAGAAAATGCAACACTTGGAA
GAGTTAAATGCTGTTCAGTGAAGATTTCAGCCCCAGGCCTTTGCTGCAAGTGACCCTGTGGCAACAGTGGATTCTCAGACATGATACTCTCATCATATTT
GCAACTCTTCTCTCTCTTTCTTCCCCACACCCAAGAGGAGGATTGGTGGTAGGGGGCAGGCAGAGGGGGTGGGGAGAAGTTTCCTGGGCTCCATCAATGG
CTGCATCTTTTCTGGACTCAGCAGTCTCCTTGATTCCATGTAGAGTGTGGAAAGGAGTTGCTGATTGCATTTCCTCTCATTAACAATTGGGTGTGTAATA
AAAAGCATTGTACTTCATCTTAAATCACTGGTAAGGCTCAGCCTACAGAAAGATTTGAAATGGCCAGAGCCAATCGCTTGGTGCATTCTGCGTAATGGTT
TCCATCTCCGATTTCCTCATCAGGGCCTGTGAATACCCAGGTGCCTGTATCTTTGCCAAGACCGTGATCAAGGTAGCTTAAGAGAGATGGTCAGGAGAAA
ACACTGTTTTTGTTTTTTTTGTTGTTTTGTTTTGTTTTGGCCAGTTAAATATCATCTCTCAAATATTGATCTCACCGTGTCAACCTTGCACTGCACAACC
TTCCTTCTGCTTCTCCCACACCCAGTATTTGCAGAAGGGCAAAGCTGCTTAAGAGAGAGGATCAGGGTGAAGTTTGGCACACAGGGTTTATTAATGGGGC
AAAAACTGCCTTTTCTTCCTCCTCCTGACCTTATTTTGCTCTTCACTCTCCCCAGCCAATAAAGCGTCTGTGGCGATTGGTGAACAGCATAAACAGCTGG
ACCTCAGCAAGGGTCAGGCAAACCCAGTCACTCGGAAGGCAGCTGTGTGAGCTGCCAAGCTAGTGGGCTTCAGGTGCAAGGGTACCTGTGCCACACCAAC
CTGGGAGCACACAGAATACTATTAATGTGCACCCAGCTGGTCTCCCCAGGCAAGAAGGTATCCTCTTCCCAAGGTGTACCCACTGAATGTTGTTACTACA
TATTGAGAGTCATTTTATGCATATGCATTCTACCTTTCCTGCTTTATGAGTATTTTTAAGCTTTTAGTTCAAGGTTATATTCAGAAAATATTTCCCAGTA
TAATGATACATCGTAGCCTAAGAAATATTTTCTCAATGTAATTCCCTTCCCAGCTACCCAAATGCTACAGAGAAATGTTTTCTACTTGGCCACTATCAGG
GTTCGTCATCTATTGTGTTGACTATTAATGGCTTTTTGATTGGGTAAGGATTTTGCTATAGATGAAGGTAGAGGGCTGTCAGCCCTGAAAAACACACAGG
TCAGACATTTAAAAGGCATGGGTTTCGAGCTGTCTCAAAATATTGCCCAATAGCCATAATTTTACCAGCCTTTCTGTCATATGCTGCTATTACAAAGTGG
AAGCTGTTGAATGTTTATTGGTGCCCAGGGTTTTGCTCTCCAATCTAGGTTCAGTTGAAGGAATATTGTTTCTAAGACTGTTTTGAGACATGTCCAGTAC
ATCACAAAGGAGATCGGGGCGACCCCTGCAGATGTGGAGCCATTAGCCCAGTTGAGGATATTCTCCAAGTTGTCCTCTCTCCTGCTGATGGAAATGGGAA
TGAAGTTAAGTGGTCTGAAAAACTTGAATCGTTCACATTTCTCAGCTCTGGGGGTCATTTACCAGTTTGTTGTAGAAGAAATAATCAGGTAAGTTAAAAG
TTCATTTCCAGAGAAGGTAAACCCCACTTACCATCTCTGCATGATTTCAGTGGGAATTGATTATCACTAATCCCCAACTGGGCTAGAATAAATGTAAAGT
TTGACCTTTTTAAAACGAAAAGAGAGACAAAGTCTCAGCACATTCCAAGGAGTGGTAGAAACAGAGCTGAAGGTGTCCCCATTGTAGATTAGTCTCTTCT
CACTAAAATTTACTTTCCAACGTAGGGCCTAAAGGAAACCTTTCTTAAAGACAGGCTGAAACCCCTTCAAAGGCAGATGAGGAGGTACAGACACGTGACC
TTTTGGTGCACACTGGAGCTACTTGGACAAGACCAGCATGCCTTGCTGCACGTGTGTGTATTTCACTGCTGAGAACATCCTTTAACTTGGTGTGCAATTT
GAAAGGATGTGAATCATGGATGGAAGGCCATTTGTACATGTCCCTTGGCAAAATTCTTTCTGGTGTCTCCTAACTTCAGAGACAGGGACTCTTTTTGGAT
CTCTATTGACAAGTAATAAAAGTCTGGCCCTCATAACTTGTTTCCGAACTAGAAAAGTCTGTGAGACCCCTACATCATTCTGGTTTTTTTGCTTGAGTAA
GAACAATCCTTTTTTATTTTTCTTCTGTACAGTCTAAAGCTACAGAGAAAAAAAAATGCACTCTTCCCTTGCCGGCTCCTGGTACCATTGGTCTGAACAG
CTGTAGTTGGTCTACTCCTTACTTAGCACTTGATTGTGTGGGGAAACAAAGGTGGGAGGGGTGGGGAATACTGGAAATAATCAGGGCAATTTTTTTCTTT
CCCATAATTGGACTAGATACCTTGGTACTGTTGACCTTCTCAGCATCTCCCTTTTGCCTTAGATGGCAACACCCTCCAGTCTGTAGCAGAGCAGTCCAAC
CCAGATTAGTGCAGCCCGGAGGCTTAGGGTGCAGCCTCCCTGGTCTTCCTCCACACAGTTGTTCACCAACAGACCAGACCTCCTTTAACCACAGTGTCAA
CATAGTATCGGAAAGAGAGCCATTTCTTAGGGGAATAAAACAGTTTCGCTTCTTTAGCTCATCTGTGGTGTCAGAATCCTTGGAGCTGAAGAGAGAAATC
AAAAGAGCATGATGATGGCTGCCTGGTTTCAGGTGGAACTTAATGCATTGATCTTTAGAAGCTCCTTCTGTTGGAAGTTGAGTACCTGTGATCTAAAATG
TCCTGGAGGCAGATGACATCTAAAATATGTGCTTTCCAACCAGCACAGCTGGCGCTCTTAGCTCCTGATTGGTTGTGTGTTTTATTAAGGATCAGTGCAG
TTAAGTCGTATTTTAAAGTGTTACCTCCCCTCCTAACCCTTCCCCTTCTTGGACACTGAAGGAAAAGGCCAACTAGGGTGTTAGCCCTCTGGGCACCAAG
GAAACTAACAGCTTTCTCAAAGCGGTGACCACTCAGGCCAGCCCAGACAAATCTGAGGGATGGCCAGTGCACTCCAATGATGGGACAGGCCTAACAACAC
ATGTAAGCTTCCCCGAGAGCTTTCAGCTGGTTCACCTCTTTGTTCTCTAGACTCTTAAGTACTGACTGCTTTGACTTTTGTGATTATGTTATGGTGATGT
GTAGTCAGTGTACCAATATGTTCACAACCTAGGATCATGATAATGGAGTGTGTTTTGGGTTTTTTTTAACTGTTCAGAAAAAAAGTAAATTACAAATATA
AGATTAAAGTGAA
  • refseq_BTRC.F1 (forward primer)
  • refseq_BTRC.R1 (reverse primer)
  • Single exon skipping

Frame 0

*ERAGGRKRRRDPGAALAAAWHQRGGPGGERTQ
WPRR
LWTRPRRCCKRRHSSL*IPQREKTVIMANP
LGR*YQRRIHLDRHTTAVPDSA*TKKQYV*QAL
L*RLRIVWPKQNLPMALPV*LCPSNGNSQQAMK
RKRNCVSNTLSSGQSQIKWNLWNILYPKCVITNM
GT*TRILNLCCREIS*LLCQLGDWIILLRTFCH
TWMPNHYVLLNLCARNGTE*PLMACCGRSLSRE
WSGQILCGEAWQNEEDGDSIYSKTNLLTGMLLPT
LFIEHFILKLYKTLRQ*NLIGDVEDIVYREFTA
EVKQAKEFTVYSMMIRK**AAFETTQSRSGIKT
HWNASEFSQAIQVQSSVSSMMRE*S*QDHRIPRS
ECGM*IQVKC*TR*FTIVKQFCTCVSIMA*W*P
APKIVPLLYGIWPPQLTLPSGGCWSDTELLSML
*TLMTSTLFLHLGIEL*RYGTQVLVNL*GP*MDT
NEALPVCSTGTGW**VAHLTTLSDYGT*NVVHV
YEC*KAMRNWCVVFDLITRG*SVGPMMEKLKCG
ILWLLWTPVLLQGHSVYGPLWSIPEEFFDYSLMN
SRLSVVHMMTQSSSGTS*MIQLPKLNPPVPLLE
HTPTSPDK*PYTDLILAQDPLKLRYLTYLPIPG
*ATTVTIKLLPSFPGLAEEQGFETPVGTQLVCSR
PRTVYSAQLTASVLLSEDVFYLL*MIGTFKPPL
LSSFHLCT*FFPIGSRQR*LINIFSVLPESLLL
CH*AEELVSLYSLLGETHF*GMGDAASSPVPSVS
LLTAGMPSTWPEQPSPNMLRRRQSSLCIASGTR
KRKHKNVYTGRFGPPACLLFVSVPLPIYSPTPL
QPFFSVCFT*EESVRRECPPLT*ARSARKCNTWK
S*MLFSEDFSPRPLLQVTLWQQWILRHDTLIIF
ATLLSLSSPHPRGGLVVGGRQRGWGEVSWAPSM
AASFLDSAVSLIPCRVWKGVADCISSH*QLGV**
KALYFILNHW*GSAYRKI*NGQSQSLGAFCVMV
SISDFLIRACEYPGACIFAKTVIKVA*ERWSGE
NTVFVFFVVLFCFGQLNIISQILISPCQPCTAQP
SFCFSHTQYLQKGKAA*ERGSG*SLAHRVY*WG
KNCLFFLLLTLFCSSLSPANKASVAIGEQHKQL
DLSKGQANPVTRKAAV*AAKLVGFRCKGTCATPT
WEHTEYY*CAPSWSPQARRYPLPKVYPLNVVTT
Y*ESFYAYAFYLSCFMSIFKLLVQGYIQKIFPS
IMIHRSLRNIFSM*FPSQLPKCYREMFSTWPLSG
FVIYCVDY*WLFDWVRILL*MKVEGCQP*KTHR
SDI*KAWVSSCLKILPNSHNFTSLSVICCYYKV
EAVECLLVPRVLLSNLGSVEGILFLRLF*DMSST
SQRRSGRPLQMWSH*PS*GYSPSCPLSC*WKWE
*S*VV*KT*IVHISQLWGSFTSLL*KK*SGKLK
VHFQRR*TPLTISA*FQWELIITNPQLG*NKCKV
*PF*NEKRDKVSAHSKEW*KQS*RCPHCRLVSS
H*NLLSNVGPKGNLS*RQAETPSKADEEVQTRD
LLVHTGATWTRPACLAARVCISLLRTSFNLVCNL
KGCESWMEGHLYMSLGKILSGVS*LQRQGLFLD
LY*QVIKVWPS*LVSELEKSVRPLHHSGFFA*V
RTILFYFSSVQSKATEKKKCTLPLPAPGTIGLNS
CSWSTPYLALDCVGKQRWEGWGILEIIRAIFFF
PIIGLDTLVLLTFSASPFCLRWQHPPVCSRAVQ
PRLVQPGGLGCSLPGLPPHSCSPTDQTSFNHSVN
IVSEREPFLRGIKQFRFFSSSVVSESLELKREI
KRA**WLPGFRWNLMH*SLEAPSVGS*VPVI*N
VLEADDI*NMCFPTSTAGALSS*LVVCFIKDQCS
*VVF*SVTSPPNPSPSWTLKEKAN*GVSPLGTK
ETNSFLKAVTTQASPDKSEGWPVHSNDGTGLTT
HVSFPESFQLVHLFVL*TLKY*LL*LL*LCYGDV
*SVYQYVHNLGS**WSVFWVFFNCSEKK*ITNI
RLK*

Frame 1

KRGRGEGRGGGIRALRWLRPGTKGAAPAESGPS
GLGD
YGPGRGGAAREGTQVYEFLRERRL**WRT
P*EDNTREEFT*TDIQQLCQTLLKPRNSMFSKHC
YED*ELCGQNKTCQWHFQYDCAQATETLSKL*K
GKGTVCQIL*AVVRVRSSGICGTSYIPNVSLPT
WAHKLVS*TYVAERFHNCSASSGIGSYC*EHSVI
PGCQITMCC*TCVQGMVPSDL*WHAVEEAYREN
GQDRFSVERPGRTKRMGTVFIQKQTS*RECSSQ
LFL*STLS*NYTRH*DNRI*LEMWKT*FTENSLP
K*NKQRSLLFTV**SENSKRPSRQHNQDLG*KH
IGMQANSHRPYRFSPLSPV**ESDHNRIIGFHG
QSVGCKYR*NAKHVDSPL*SSSALAFQ*WHDGDL
LQRSFHCCMGYGLPN*HYPPEGAGRTPSCCQCC
RL**QVHCFCIWG*NYKGMEHKYL*ICKDLKWT
QTRHCLFAVQGQAGSEWLI*QHYQIMGHRMWCMF
TSVRRP*GIGALYSI**QEDSQWGL*WKN*SVG
SCGCFGPPCSCRDTLSTDPCGAFRKSFSTTV**
IPDCQ*FT**HNPHLGLPK*SSCPS*TPPFPFSN
IHLHLQINNHTLTSYLPRTH*SCGI*RICQYQD
EQQQ*QSNYCPVSLD*PRSRALRLLLGHSWSAV
GPGRSTQHN*LLQCCYQKMSSIFCE*LELLNLPS
SPPFTSAPSFFPLVPDKGDL*IYLVFCQNLSCF
AIKQKN*FPCIACWERPTSRVWGMQLQAQCPVS
PC*LQECQAPGQSSPAPICLGGDRVPSV*PLGQE
KENTRMYTLEDLGLLPAFSLFLFLFPSTPLRPF
NLFSLSASPEKKVYEESVLLSHEPDQPENATLG
RVKCCSVKISAPGLCCK*PCGNSGFSDMILSSYL
QLFSLFLPHTQEEDWW*GAGRGGGEKFPGLHQW
LHLFWTQQSP*FHVECGKELLIAFPLINNWVCN
KKHCTSS*ITGKAQPTERFEMARANRLVHSA*WF
PSPISSSGPVNTQVPVSLPRP*SR*LKRDGQEK
TLFLFFLLFCFVLAS*ISSLKY*SHRVNLALHN
LPSASPTPSICRRAKLLKREDQGEVWHTGFINGA
KTAFSSSS*PYFALHSPQPIKRLWRLVNSINSW
TSARVRQTQSLGRQLCELPS*WASGARVPVPHQ
PGSTQNTINVHPAGLPRQEGILFPRCTH*MLLLH
IESHFMHMHSTFPAL*VFLSF*FKVIFRKYFPV
**YIVA*EIFSQCNSLPSYPNATEKCFLLGHYQ
GSSSIVLTINGFLIG*GFCYR*R*RAVSPEKHTG
QTFKRHGFRAVSKYCPIAIILPAFLSYAAITKW
KLLNVYWCPGFCSPI*VQLKEYCF*DCFETCPV
HHKGDRGDPCRCGAISPVEDILQVVLSPADGNGN
EVKWSEKLESFTFLSSGGHLPVCCRRNNQVS*K
FISREGKPHLPSLHDFSGN*LSLIPNWARINVK
FDLFKTKRETKSQHIPRSGRNRAEGVPIVD*SLL
TKIYFPT*GLKETFLKDRLKPLQRQMRRYRHVT
FWCTLELLGQDQHALLHVCVFHC*EHPLTWCAI
*KDVNHGWKAICTCPLAKFFLVSPNFRDRDSFWI
SIDK**KSGPHNLFPN*KSL*DPYIILVFLLE*
EQSFFIFLLYSLKLQRKKNALFPCRLLVPLV*T
AVVGLLLT*HLIVWGNKGGRGGEYWK*SGQFFSF
P*LD*IPWYC*PSQHLPFALDGNTLQSVAEQSN
PD*CSPEA*GAASLVFLHTVVHQQTRPPLTTVS
T*YRKESHFLGE*NSFASLAHLWCQNPWS*REKS
KEHDDGCLVSGGT*CIDL*KLLLLEVEYL*SKM
SWRQMTSKICAFQPAQLALLAPDWLCVLLRISA
VKSYFKVLPPLLTLPLLGH*RKRPTRVLALWAPR
KLTAFSKR*PLRPAQTNLRDGQCTPMMGQA*QH
M*ASPRAFSWFTSLFSRLLSTDCFDFCDYVMVM
CSQCTNMFTT*DHDNGVCFGFFLTVQKKSKLQI*
D*SE

Frame 2

REGGGKEEEAGSGRCVGCGLAPKGRPRRRADPV
ASAI
MDPAEAVLQEKALKFMNSSEREDCNNGEP
PRKIIPEKNSLRQTYNSCARLCLNQETVCLAST
AMKTENCVAKTKLANGTSSMIVPKQRKLSASYEK
EKELCVKYFEQWSESDQVEFVEHLISQMCHYQH
GHINSYLKPMLQRDFITALPARGLDHIAENILS
YLDAKSLCAAELVCKEWYRVTSDGMLWKKLIERM
VRTDSLWRGLAERRGWGQYLFKNKPPDGNAPPN
SFYRALYPKIIQDIETIESNWRCGRHSLQRIHC
RSETSKGVYCLQYDDQKIVSGLRDNTIKIWDKNT
LECKRILTGHTGSVLCLQYDERVIITGSSDSTV
RVWDVNTGEMLNTLIHHCEAVLHLRFNNGMMVT
CSKDRSIAVWDMASPTDITLRRVLVGHRAAVNVV
DFDDKYIVSASGDRTIKVWNTSTCEFVRTLNGH
KRGIACLQYRDRLVVSGSSDNTIRLWDIECGAC
LRVLEGHEELVRCIRFDNKRIVSGAYDGKIKVWD
LVAALDPRAPAGTLCLRTLVEHSGRVFRLQFDE
FQIVSSSHDDTILIWDFLNDPAAQAEPPRSPSR
TYTYISR*ITIH*PHTCPGPIKVAVFNVSANTRM
SNNSNNQTTAQFPWTSRGAGL*DSCWDTVGLQS
AQDGLLSTTDCFSAAIRRCLLSFVNDWNF*TSP
PLLLSPLHLVFSHWFQTKVTYKYI*CFARISLAL
PLSRRTSFPV*PAGRDPLLGYGGCSFKPSAQCL
PVNCRNAKHLARAAQPQYA*EETEFPLYSLWDK
KKKTQECIHWKIWASCLPSLCFCSSSHLLPYAPS
TFFLCLLHLRRKCTKRVSSSHMSQISQKMQHLE
ELNAVQ*RFQPQAFAASDPVATVDSQT*YSHHI
CNSSLSFFPTPKRRIGGRGQAEGVGRSFLGSING
CIFSGLSSLLDSM*SVERSC*LHFLSLTIGCVI
KSIVLHLKSLVRLSLQKDLKWPEPIAWCILRNG
FHLRFPHQGL*IPRCLYLCQDRDQGSLREMVRRK
HCFCFFCCFVLFWPVKYHLSNIDLTVSTLHCTT
FLLLLPHPVFAEGQSCLRERIRVKFGTQGLLMG
QKLPFLPPPDLILLFTLPSQ*SVCGDW*TA*TAG
PQQGSGKPSHSEGSCVSCQASGLQVQGYLCHTN
LGAHRILLMCTQLVSPGKKVSSSQGVPTECCYY
ILRVILCICILPFLLYEYF*AFSSRLYSENISQY
NDTS*PKKYFLNVIPFPATQMLQRNVFYLATIR
VRHLLC*LLMAF*LGKDFAIDEGRGLSALKNTQ
VRHLKGMGFELSQNIAQ*P*FYQPFCHMLLLQSG
SC*MFIGAQGFALQSRFS*RNIVSKTVLRHVQY
ITKEIGATPADVEPLAQLRIFSKLSSLLLMEMG
MKLSGLKNLNRSHFSALGVIYQFVVEEIIR*VKS
SFPEKVNPTYHLCMISVGIDYH*SPTGLE*M*S
LTFLKRKERQSLSTFQGVVETELKVSPL*ISLF
SLKFTFQRRA*RKPFLKTG*NPFKGR*GGTDT*P
FGAHWSYLDKTSMPCCTCVYFTAENIL*LGVQF
ERM*IMDGRPFVHVPWQNSFWCLLTSETGTLFG
SLLTSNKSLALITCFRTRKVCETPTSFWFFCLSK
NNPFLFFFCTV*SYREKKMHSSLAGSWYHWSEQ
L*LVYSLLST*LCGETKVGGVGNTGNNQGNFFL
SHNWTRYLGTVDLLSISLLP*MATPSSL*QSSPT
QISAARRLRVQPPWSSSTQLFTNRPDLL*PQCQ
HSIGKRAIS*GNKTVSLL*LICGVRILGAEERN
QKSMMMAAWFQVELNALIFRSSFCWKLSTCDLKC
PGGR*HLKYVLSNQHSWRS*LLIGCVFY*GSVQ
LSRILKCYLPS*PFPFLDTEGKGQLGC*PSGHQ
GN*QLSQSGDHSGQPRQI*GMASALQ*WDRPNNT
CKLPRELSAGSPLCSLDS*VLTALTFVIMLW*C
VVSVPICSQPRIMIMECVLGFF*LFRKKVNYKY
KIKV

Sequence NM_033637

TAAGAGAGGGCGGGGGGAAGGAAGAGGAGGCGGGATCCGGGCGCTGCGTTGGCTGCGGCCTGGCACCAAAGGGGCGGCCCCGGCGGAGAGCGGACCCAGT
GGCCTCGGCGAT
TATGGACCCGGCCGAGGCGGTGCTGCAAGAGAAGGCACTCAAGTTTATGTGCTCTATGCCCAGGTCTCTGTGGCTGGGCTGCTCCAGC
CTGGCGGACAGCATGCCTTCGCTGCGATGCCTGTATAACCCAGGGACTGGCGCACTCACAGCTTTCCAG
AATTCCTCAGAGAGAGAAGACTGTAATAATG
GCGAACCCCCTAGGAAGATAATACCAGAGAAGAATTCACTTAGACAGACATACAACAGCTGTGCCAGACTCTGCTTAAACCAAGAAACAGTATGTTTAGC
AAGCACTGCTATGAAGACTGAGAATTGTGTGGCCAAAACAAAACTTGCCAATGGCACTTCCAGTATGATTGTGCCCAAGCAACGGAAACTCTCAGCAAGC
TATGAAAAGGAAAAGGAACTGTGTGTCAAATACTTTGAGCAGTGGTCAGAGTCAGATCAAGTGGAATTTGTGGAACATCTTATATCCCAAATGTGTCATT
ACCAACATGGGCACATAAACTCGTATCTTAAACCTATGTTGCAGAGAGATTTCATAACTGCTCTGCCAGCTCGGGGATTGGATCATATTGCTGAGAACAT
TCTGTCATACCTGGATGCCAAATCACTATGTGCTGCTGAACTTGTGTGCAAGGAATGGTACCGAGTGACCTCTGATGGCATGCTGTGGAAGAAGCTTATC
GAGAGAATGGTCAGGACAGATTCTCTGTGGAGAGGCCTGGCAGAACGAAGAGGATGGGGACAGTATTTATTCAAAAACAAACCTCCTGACGGGAATGCTC
CTCCCAACTCTTTTTATAGAGCACTTTATCCTAAAATTATACAAGACATTGAGACAATAGAATCTAATTGGAGATGTGGAAGACATAGTTTACAGAGAAT
TCACTGCCGAAGTGAAACAAGCAAAGGAGTTTACTGTTTACAGTATGATGATCAGAAAATAGTAAGCGGCCTTCGAGACAACACAATCAAGATCTGGGAT
AAAAACACATTGGAATGCAAGCGAATTCTCACAGGCCATACAGGTTCAGTCCTCTGTCTCCAGTATGATGAGAGAGTGATCATAACAGGATCATCGGATT
CCACGGTCAGAGTGTGGGATGTAAATACAGGTGAAATGCTAAACACGTTGATTCACCATTGTGAAGCAGTTCTGCACTTGCGTTTCAATAATGGCATGAT
GGTGACCTGCTCCAAAGATCGTTCCATTGCTGTATGGGATATGGCCTCCCCAACTGACATTACCCTCCGGAGGGTGCTGGTCGGACACCGAGCTGCTGTC
AATGTTGTAGACTTTGATGACAAGTACATTGTTTCTGCATCTGGGGATAGAACTATAAAGGTATGGAACACAAGTACTTGTGAATTTGTAAGGACCTTAA
ATGGACACAAACGAGGCATTGCCTGTTTGCAGTACAGGGACAGGCTGGTAGTGAGTGGCTCATCTGACAACACTATCAGATTATGGGACATAGAATGTGG
TGCATGTTTACGAGTGTTAGAAGGCCATGAGGAATTGGTGCGTTGTATTCGATTTGATAACAAGAGGATAGTCAGTGGGGCCTATGATGGAAAAATTAAA
GTGTGGGATCTTGTGGCTGCTTTGGACCCCCGTGCTCCTGCAGGGACACTCTGTCTACGGACCCTTGTGGAGCATTCCGGAAGAGTTTTTCGACTACAGT
TTGATGAATTCCAGATTGTCAGTAGTTCACATGATGACACAATCCTCATCTGGGACTTCCTAAATGATCCAGCTGCCCAAGCTGAACCCCCCCGTTCCCC
TTCTCGAACATACACCTACATCTCCAGATAAATAACCATACACTGACCTCATACTTGCCCAGGACCCATTAAAGTTGCGGTATTTAACGTATCTGCCAAT
ACCAGGATGAGCAACAACAGTAACAATCAAACTACTGCCCAGTTTCCCTGGACTAGCCGAGGAGCAGGGCTTTGAGACTCCTGTTGGGACACAGTTGGTC
TGCAGTCGGCCCAGGACGGTCTACTCAGCACAACTGACTGCTTCAGTGCTGCTATCAGAAGATGTCTTCTATCTTTTGTGAATGATTGGAACTTTTAAAC
CTCCCCTCCTCTCCTCCTTTCACCTCTGCACCTAGTTTTTTCCCATTGGTTCCAGACAAAGGTGACTTATAAATATATTTAGTGTTTTGCCAGAATCTCT
CTTGCTTTGCCATTAAGCAGAAGAACTAGTTTCCCTGTATAGCCTGCTGGGAGAGACCCACTTCTAGGGTATGGGGGATGCAGCTTCAAGCCCAGTGCCC
AGTGTCTCCCTGTTAACTGCAGGAATGCCAAGCACCTGGCCAGAGCAGCCCAGCCCCAATATGCTTAGGAGGAGACAGAGTTCCCTCTGTATAGCCTCTG
GGACAAGAAAAAGAAAACACAAGAATGTATACACTGGAAGATTTGGGCCTCCTGCCTGCCTTCTCTTTGTTTCTGTTCCTCTTCCCATCTACTCCCCTAC
GCCCCTTCAACCTTTTTTCTCTGTCTGCTTCACCTGAGAAGAAAGTGTACGAAGAGAGTGTCCTCCTCTCACATGAGCCAGATCAGCCAGAAAATGCAAC
ACTTGGAAGAGTTAAATGCTGTTCAGTGAAGATTTCAGCCCCAGGCCTTTGCTGCAAGTGACCCTGTGGCAACAGTGGATTCTCAGACATGATACTCTCA
TCATATTTGCAACTCTTCTCTCTCTTTCTTCCCCACACCCAAGAGGAGGATTGGTGGTAGGGGGCAGGCAGAGGGGGTGGGGAGAAGTTTCCTGGGCTCC
ATCAATGGCTGCATCTTTTCTGGACTCAGCAGTCTCCTTGATTCCATGTAGAGTGTGGAAAGGAGTTGCTGATTGCATTTCCTCTCATTAACAATTGGGT
GTGTAATAAAAAGCATTGTACTTCATCTTAAATCACTGGTAAGGCTCAGCCTACAGAAAGATTTGAAATGGCCAGAGCCAATCGCTTGGTGCATTCTGCG
TAATGGTTTCCATCTCCGATTTCCTCATCAGGGCCTGTGAATACCCAGGTGCCTGTATCTTTGCCAAGACCGTGATCAAGGTAGCTTAAGAGAGATGGTC
AGGAGAAAACACTGTTTTTGTTTTTTTTGTTGTTTTGTTTTGTTTTGGCCAGTTAAATATCATCTCTCAAATATTGATCTCACCGTGTCAACCTTGCACT
GCACAACCTTCCTTCTGCTTCTCCCACACCCAGTATTTGCAGAAGGGCAAAGCTGCTTAAGAGAGAGGATCAGGGTGAAGTTTGGCACACAGGGTTTATT
AATGGGGCAAAAACTGCCTTTTCTTCCTCCTCCTGACCTTATTTTGCTCTTCACTCTCCCCAGCCAATAAAGCGTCTGTGGCGATTGGTGAACAGCATAA
ACAGCTGGACCTCAGCAAGGGTCAGGCAAACCCAGTCACTCGGAAGGCAGCTGTGTGAGCTGCCAAGCTAGTGGGCTTCAGGTGCAAGGGTACCTGTGCC
ACACCAACCTGGGAGCACACAGAATACTATTAATGTGCACCCAGCTGGTCTCCCCAGGCAAGAAGGTATCCTCTTCCCAAGGTGTACCCACTGAATGTTG
TTACTACATATTGAGAGTCATTTTATGCATATGCATTCTACCTTTCCTGCTTTATGAGTATTTTTAAGCTTTTAGTTCAAGGTTATATTCAGAAAATATT
TCCCAGTATAATGATACATCGTAGCCTAAGAAATATTTTCTCAATGTAATTCCCTTCCCAGCTACCCAAATGCTACAGAGAAATGTTTTCTACTTGGCCA
CTATCAGGGTTCGTCATCTATTGTGTTGACTATTAATGGCTTTTTGATTGGGTAAGGATTTTGCTATAGATGAAGGTAGAGGGCTGTCAGCCCTGAAAAA
CACACAGGTCAGACATTTAAAAGGCATGGGTTTCGAGCTGTCTCAAAATATTGCCCAATAGCCATAATTTTACCAGCCTTTCTGTCATATGCTGCTATTA
CAAAGTGGAAGCTGTTGAATGTTTATTGGTGCCCAGGGTTTTGCTCTCCAATCTAGGTTCAGTTGAAGGAATATTGTTTCTAAGACTGTTTTGAGACATG
TCCAGTACATCACAAAGGAGATCGGGGCGACCCCTGCAGATGTGGAGCCATTAGCCCAGTTGAGGATATTCTCCAAGTTGTCCTCTCTCCTGCTGATGGA
AATGGGAATGAAGTTAAGTGGTCTGAAAAACTTGAATCGTTCACATTTCTCAGCTCTGGGGGTCATTTACCAGTTTGTTGTAGAAGAAATAATCAGGTAA
GTTAAAAGTTCATTTCCAGAGAAGGTAAACCCCACTTACCATCTCTGCATGATTTCAGTGGGAATTGATTATCACTAATCCCCAACTGGGCTAGAATAAA
TGTAAAGTTTGACCTTTTTAAAACGAAAAGAGAGACAAAGTCTCAGCACATTCCAAGGAGTGGTAGAAACAGAGCTGAAGGTGTCCCCATTGTAGATTAG
TCTCTTCTCACTAAAATTTACTTTCCAACGTAGGGCCTAAAGGAAACCTTTCTTAAAGACAGGCTGAAACCCCTTCAAAGGCAGATGAGGAGGTACAGAC
ACGTGACCTTTTGGTGCACACTGGAGCTACTTGGACAAGACCAGCATGCCTTGCTGCACGTGTGTGTATTTCACTGCTGAGAACATCCTTTAACTTGGTG
TGCAATTTGAAAGGATGTGAATCATGGATGGAAGGCCATTTGTACATGTCCCTTGGCAAAATTCTTTCTGGTGTCTCCTAACTTCAGAGACAGGGACTCT
TTTTGGATCTCTATTGACAAGTAATAAAAGTCTGGCCCTCATAACTTGTTTCCGAACTAGAAAAGTCTGTGAGACCCCTACATCATTCTGGTTTTTTTGC
TTGAGTAAGAACAATCCTTTTTTATTTTTCTTCTGTACAGTCTAAAGCTACAGAGAAAAAAAAATGCACTCTTCCCTTGCCGGCTCCTGGTACCATTGGT
CTGAACAGCTGTAGTTGGTCTACTCCTTACTTAGCACTTGATTGTGTGGGGAAACAAAGGTGGGAGGGGTGGGGAATACTGGAAATAATCAGGGCAATTT
TTTTCTTTCCCATAATTGGACTAGATACCTTGGTACTGTTGACCTTCTCAGCATCTCCCTTTTGCCTTAGATGGCAACACCCTCCAGTCTGTAGCAGAGC
AGTCCAACCCAGATTAGTGCAGCCCGGAGGCTTAGGGTGCAGCCTCCCTGGTCTTCCTCCACACAGTTGTTCACCAACAGACCAGACCTCCTTTAACCAC
AGTGTCAACATAGTATCGGAAAGAGAGCCATTTCTTAGGGGAATAAAACAGTTTCGCTTCTTTAGCTCATCTGTGGTGTCAGAATCCTTGGAGCTGAAGA
GAGAAATCAAAAGAGCATGATGATGGCTGCCTGGTTTCAGGTGGAACTTAATGCATTGATCTTTAGAAGCTCCTTCTGTTGGAAGTTGAGTACCTGTGAT
CTAAAATGTCCTGGAGGCAGATGACATCTAAAATATGTGCTTTCCAACCAGCACAGCTGGCGCTCTTAGCTCCTGATTGGTTGTGTGTTTTATTAAGGAT
CAGTGCAGTTAAGTCGTATTTTAAAGTGTTACCTCCCCTCCTAACCCTTCCCCTTCTTGGACACTGAAGGAAAAGGCCAACTAGGGTGTTAGCCCTCTGG
GCACCAAGGAAACTAACAGCTTTCTCAAAGCGGTGACCACTCAGGCCAGCCCAGACAAATCTGAGGGATGGCCAGTGCACTCCAATGATGGGACAGGCCT
AACAACACATGTAAGCTTCCCCGAGAGCTTTCAGCTGGTTCACCTCTTTGTTCTCTAGACTCTTAAGTACTGACTGCTTTGACTTTTGTGATTATGTTAT
GGTGATGTGTAGTCAGTGTACCAATATGTTCACAACCTAGGATCATGATAATGGAGTGTGTTTTGGGTTTTTTTTAACTGTTCAGAAAAAAAGTAAATTA
CAAATATAAGATTAAAGTGAA
  • refseq_BTRC.F1 (forward primer)
  • refseq_BTRC.R1 (reverse primer)
  • Single exon skipping

Frame 0

*ERAGGRKRRRDPGAALAAAWHQRGGPGGERTQ
WPRR
LWTRPRRCCKRRHSSLCALCPGLCGWAAPA
WRTACLRCDACITQGLAHSQLSR
IPQREKTVIM
ANPLGR*YQRRIHLDRHTTAVPDSA*TKKQYV*
QALL*RLRIVWPKQNLPMALPV*LCPSNGNSQQA
MKRKRNCVSNTLSSGQSQIKWNLWNILYPKCVI
TNMGT*TRILNLCCREIS*LLCQLGDWIILLRT
FCHTWMPNHYVLLNLCARNGTE*PLMACCGRSLS
REWSGQILCGEAWQNEEDGDSIYSKTNLLTGML
LPTLFIEHFILKLYKTLRQ*NLIGDVEDIVYRE
FTAEVKQAKEFTVYSMMIRK**AAFETTQSRSGI
KTHWNASEFSQAIQVQSSVSSMMRE*S*QDHRI
PRSECGM*IQVKC*TR*FTIVKQFCTCVSIMA*
W*PAPKIVPLLYGIWPPQLTLPSGGCWSDTELLS
ML*TLMTSTLFLHLGIEL*RYGTQVLVNL*GP*
MDTNEALPVCSTGTGW**VAHLTTLSDYGT*NV
VHVYEC*KAMRNWCVVFDLITRG*SVGPMMEKLK
CGILWLLWTPVLLQGHSVYGPLWSIPEEFFDYS
LMNSRLSVVHMMTQSSSGTS*MIQLPKLNPPVP
LLEHTPTSPDK*PYTDLILAQDPLKLRYLTYLPI
PG*ATTVTIKLLPSFPGLAEEQGFETPVGTQLV
CSRPRTVYSAQLTASVLLSEDVFYLL*MIGTFK
PPLLSSFHLCT*FFPIGSRQR*LINIFSVLPESL
LLCH*AEELVSLYSLLGETHF*GMGDAASSPVP
SVSLLTAGMPSTWPEQPSPNMLRRRQSSLCIAS
GTRKRKHKNVYTGRFGPPACLLFVSVPLPIYSPT
PLQPFFSVCFT*EESVRRECPPLT*ARSARKCN
TWKS*MLFSEDFSPRPLLQVTLWQQWILRHDTL
IIFATLLSLSSPHPRGGLVVGGRQRGWGEVSWAP
SMAASFLDSAVSLIPCRVWKGVADCISSH*QLG
V**KALYFILNHW*GSAYRKI*NGQSQSLGAFC
VMVSISDFLIRACEYPGACIFAKTVIKVA*ERWS
GENTVFVFFVVLFCFGQLNIISQILISPCQPCT
AQPSFCFSHTQYLQKGKAA*ERGSG*SLAHRVY
*WGKNCLFFLLLTLFCSSLSPANKASVAIGEQHK
QLDLSKGQANPVTRKAAV*AAKLVGFRCKGTCA
TPTWEHTEYY*CAPSWSPQARRYPLPKVYPLNV
VTTY*ESFYAYAFYLSCFMSIFKLLVQGYIQKIF
PSIMIHRSLRNIFSM*FPSQLPKCYREMFSTWP
LSGFVIYCVDY*WLFDWVRILL*MKVEGCQP*K
THRSDI*KAWVSSCLKILPNSHNFTSLSVICCYY
KVEAVECLLVPRVLLSNLGSVEGILFLRLF*DM
SSTSQRRSGRPLQMWSH*PS*GYSPSCPLSC*W
KWE*S*VV*KT*IVHISQLWGSFTSLL*KK*SGK
LKVHFQRR*TPLTISA*FQWELIITNPQLG*NK
CKV*PF*NEKRDKVSAHSKEW*KQS*RCPHCRL
VSSH*NLLSNVGPKGNLS*RQAETPSKADEEVQT
RDLLVHTGATWTRPACLAARVCISLLRTSFNLV
CNLKGCESWMEGHLYMSLGKILSGVS*LQRQGL
FLDLY*QVIKVWPS*LVSELEKSVRPLHHSGFFA
*VRTILFYFSSVQSKATEKKKCTLPLPAPGTIG
LNSCSWSTPYLALDCVGKQRWEGWGILEIIRAI
FFFPIIGLDTLVLLTFSASPFCLRWQHPPVCSRA
VQPRLVQPGGLGCSLPGLPPHSCSPTDQTSFNH
SVNIVSEREPFLRGIKQFRFFSSSVVSESLELK
REIKRA**WLPGFRWNLMH*SLEAPSVGS*VPVI
*NVLEADDI*NMCFPTSTAGALSS*LVVCFIKD
QCS*VVF*SVTSPPNPSPSWTLKEKAN*GVSPL
GTKETNSFLKAVTTQASPDKSEGWPVHSNDGTGL
TTHVSFPESFQLVHLFVL*TLKY*LL*LL*LCY
GDV*SVYQYVHNLGS**WSVFWVFFNCSEKK*I
TNIRLK*

Frame 1

KRGRGEGRGGGIRALRWLRPGTKGAAPAESGPS
GLGD
YGPGRGGAAREGTQVYVLYAQVSVAGLLQ
PGGQHAFAAMPV*PRDWRTHSFP
EFLRERRL**W
RTP*EDNTREEFT*TDIQQLCQTLLKPRNSMFS
KHCYED*ELCGQNKTCQWHFQYDCAQATETLSK
L*KGKGTVCQIL*AVVRVRSSGICGTSYIPNVSL
PTWAHKLVS*TYVAERFHNCSASSGIGSYC*EH
SVIPGCQITMCC*TCVQGMVPSDL*WHAVEEAY
RENGQDRFSVERPGRTKRMGTVFIQKQTS*RECS
SQLFL*STLS*NYTRH*DNRI*LEMWKT*FTEN
SLPK*NKQRSLLFTV**SENSKRPSRQHNQDLG
*KHIGMQANSHRPYRFSPLSPV**ESDHNRIIGF
HGQSVGCKYR*NAKHVDSPL*SSSALAFQ*WHD
GDLLQRSFHCCMGYGLPN*HYPPEGAGRTPSCC
QCCRL**QVHCFCIWG*NYKGMEHKYL*ICKDLK
WTQTRHCLFAVQGQAGSEWLI*QHYQIMGHRMW
CMFTSVRRP*GIGALYSI**QEDSQWGL*WKN*
SVGSCGCFGPPCSCRDTLSTDPCGAFRKSFSTTV
**IPDCQ*FT**HNPHLGLPK*SSCPS*TPPFP
FSNIHLHLQINNHTLTSYLPRTH*SCGI*RICQ
YQDEQQQ*QSNYCPVSLD*PRSRALRLLLGHSWS
AVGPGRSTQHN*LLQCCYQKMSSIFCE*LELLN
LPSSPPFTSAPSFFPLVPDKGDL*IYLVFCQNL
SCFAIKQKN*FPCIACWERPTSRVWGMQLQAQCP
VSPC*LQECQAPGQSSPAPICLGGDRVPSV*PL
GQEKENTRMYTLEDLGLLPAFSLFLFLFPSTPL
RPFNLFSLSASPEKKVYEESVLLSHEPDQPENAT
LGRVKCCSVKISAPGLCCK*PCGNSGFSDMILS
SYLQLFSLFLPHTQEEDWW*GAGRGGGEKFPGL
HQWLHLFWTQQSP*FHVECGKELLIAFPLINNWV
CNKKHCTSS*ITGKAQPTERFEMARANRLVHSA
*WFPSPISSSGPVNTQVPVSLPRP*SR*LKRDG
QEKTLFLFFLLFCFVLAS*ISSLKY*SHRVNLAL
HNLPSASPTPSICRRAKLLKREDQGEVWHTGFI
NGAKTAFSSSS*PYFALHSPQPIKRLWRLVNSI
NSWTSARVRQTQSLGRQLCELPS*WASGARVPVP
HQPGSTQNTINVHPAGLPRQEGILFPRCTH*ML
LLHIESHFMHMHSTFPAL*VFLSF*FKVIFRKY
FPV**YIVA*EIFSQCNSLPSYPNATEKCFLLGH
YQGSSSIVLTINGFLIG*GFCYR*R*RAVSPEK
HTGQTFKRHGFRAVSKYCPIAIILPAFLSYAAI
TKWKLLNVYWCPGFCSPI*VQLKEYCF*DCFETC
PVHHKGDRGDPCRCGAISPVEDILQVVLSPADG
NGNEVKWSEKLESFTFLSSGGHLPVCCRRNNQV
S*KFISREGKPHLPSLHDFSGN*LSLIPNWARIN
VKFDLFKTKRETKSQHIPRSGRNRAEGVPIVD*
SLLTKIYFPT*GLKETFLKDRLKPLQRQMRRYR
HVTFWCTLELLGQDQHALLHVCVFHC*EHPLTWC
AI*KDVNHGWKAICTCPLAKFFLVSPNFRDRDS
FWISIDK**KSGPHNLFPN*KSL*DPYIILVFL
LE*EQSFFIFLLYSLKLQRKKNALFPCRLLVPLV
*TAVVGLLLT*HLIVWGNKGGRGGEYWK*SGQF
FSFP*LD*IPWYC*PSQHLPFALDGNTLQSVAE
QSNPD*CSPEA*GAASLVFLHTVVHQQTRPPLTT
VST*YRKESHFLGE*NSFASLAHLWCQNPWS*R
EKSKEHDDGCLVSGGT*CIDL*KLLLLEVEYL*
SKMSWRQMTSKICAFQPAQLALLAPDWLCVLLRI
SAVKSYFKVLPPLLTLPLLGH*RKRPTRVLALW
APRKLTAFSKR*PLRPAQTNLRDGQCTPMMGQA
*QHM*ASPRAFSWFTSLFSRLLSTDCFDFCDYVM
VMCSQCTNMFTT*DHDNGVCFGFFLTVQKKSKL
QI*D*SE

Frame 2

REGGGKEEEAGSGRCVGCGLAPKGRPRRRADPV
ASAI
MDPAEAVLQEKALKFMCSMPRSLWLGCSS
LADSMPSLRCLYNPGTGALTAFQ
NSSEREDCNN
GEPPRKIIPEKNSLRQTYNSCARLCLNQETVCLA
STAMKTENCVAKTKLANGTSSMIVPKQRKLSAS
YEKEKELCVKYFEQWSESDQVEFVEHLISQMCH
YQHGHINSYLKPMLQRDFITALPARGLDHIAENI
LSYLDAKSLCAAELVCKEWYRVTSDGMLWKKLI
ERMVRTDSLWRGLAERRGWGQYLFKNKPPDGNA
PPNSFYRALYPKIIQDIETIESNWRCGRHSLQRI
HCRSETSKGVYCLQYDDQKIVSGLRDNTIKIWD
KNTLECKRILTGHTGSVLCLQYDERVIITGSSD
STVRVWDVNTGEMLNTLIHHCEAVLHLRFNNGMM
VTCSKDRSIAVWDMASPTDITLRRVLVGHRAAV
NVVDFDDKYIVSASGDRTIKVWNTSTCEFVRTL
NGHKRGIACLQYRDRLVVSGSSDNTIRLWDIECG
ACLRVLEGHEELVRCIRFDNKRIVSGAYDGKIK
VWDLVAALDPRAPAGTLCLRTLVEHSGRVFRLQ
FDEFQIVSSSHDDTILIWDFLNDPAAQAEPPRSP
SRTYTYISR*ITIH*PHTCPGPIKVAVFNVSAN
TRMSNNSNNQTTAQFPWTSRGAGL*DSCWDTVG
LQSAQDGLLSTTDCFSAAIRRCLLSFVNDWNF*T
SPPLLLSPLHLVFSHWFQTKVTYKYI*CFARIS
LALPLSRRTSFPV*PAGRDPLLGYGGCSFKPSA
QCLPVNCRNAKHLARAAQPQYA*EETEFPLYSLW
DKKKKTQECIHWKIWASCLPSLCFCSSSHLLPY
APSTFFLCLLHLRRKCTKRVSSSHMSQISQKMQ
HLEELNAVQ*RFQPQAFAASDPVATVDSQT*YSH
HICNSSLSFFPTPKRRIGGRGQAEGVGRSFLGS
INGCIFSGLSSLLDSM*SVERSC*LHFLSLTIG
CVIKSIVLHLKSLVRLSLQKDLKWPEPIAWCILR
NGFHLRFPHQGL*IPRCLYLCQDRDQGSLREMV
RRKHCFCFFCCFVLFWPVKYHLSNIDLTVSTLH
CTTFLLLLPHPVFAEGQSCLRERIRVKFGTQGLL
MGQKLPFLPPPDLILLFTLPSQ*SVCGDW*TA*
TAGPQQGSGKPSHSEGSCVSCQASGLQVQGYLC
HTNLGAHRILLMCTQLVSPGKKVSSSQGVPTECC
YYILRVILCICILPFLLYEYF*AFSSRLYSENI
SQYNDTS*PKKYFLNVIPFPATQMLQRNVFYLA
TIRVRHLLC*LLMAF*LGKDFAIDEGRGLSALKN
TQVRHLKGMGFELSQNIAQ*P*FYQPFCHMLLL
QSGSC*MFIGAQGFALQSRFS*RNIVSKTVLRH
VQYITKEIGATPADVEPLAQLRIFSKLSSLLLME
MGMKLSGLKNLNRSHFSALGVIYQFVVEEIIR*
VKSSFPEKVNPTYHLCMISVGIDYH*SPTGLE*
M*SLTFLKRKERQSLSTFQGVVETELKVSPL*IS
LFSLKFTFQRRA*RKPFLKTG*NPFKGR*GGTD
T*PFGAHWSYLDKTSMPCCTCVYFTAENIL*LG
VQFERM*IMDGRPFVHVPWQNSFWCLLTSETGTL
FGSLLTSNKSLALITCFRTRKVCETPTSFWFFC
LSKNNPFLFFFCTV*SYREKKMHSSLAGSWYHW
SEQL*LVYSLLST*LCGETKVGGVGNTGNNQGNF
FLSHNWTRYLGTVDLLSISLLP*MATPSSL*QS
SPTQISAARRLRVQPPWSSSTQLFTNRPDLL*P
QCQHSIGKRAIS*GNKTVSLL*LICGVRILGAEE
RNQKSMMMAAWFQVELNALIFRSSFCWKLSTCD
LKCPGGR*HLKYVLSNQHSWRS*LLIGCVFY*G
SVQLSRILKCYLPS*PFPFLDTEGKGQLGC*PSG
HQGN*QLSQSGDHSGQPRQI*GMASALQ*WDRP
NNTCKLPRELSAGSPLCSLDS*VLTALTFVIML
W*CVVSVPICSQPRIMIMECVLGFF*LFRKKVNY
KYKIKV

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