Sequences - Rnomics 📊 Palace

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Sequences

Sequence NM_182641

CGCCCCCCCTGCGCCCGCCCCTCCCCCTTCGCTTTCCTTCTCCCCCCGCCTCGGCTCCGACATGAGGGGCCGGCGGGGCAGGCCGCCCAAGCAGCCCGCG GCTCCCGCTGCGGAGCGCTGCGCCCCGGCCCCGCCGCCACCGCCGCCGCCGCCCACGTCCGGACCCATCGGGGGGCTCCGCTCGCGGCACCGCGGCAGCA GCCGGGGCAGGTGGGCCGCCGCCCAGGCTGAGGTGGCGCCCAAGACGCGGCTGAGCTCGCCCAGGGGGGGCAGCAGTAGCCGGAGGAAGCCGCCGCCGCC GCCGCCGGCCCCCCCCAGCACCAGCGCCCCGGGCCGGGGGGGGCGAGGAGGCGGGGGCGGCAGGACGGGGGGCGGGGGCGGCGGCGGCCACCTGGCCCGG ACCACCGCGGCCCGGAGGGCCGTCAACAAAGTGGTGTACGATGACCACGAGAGCGAGGAGGAGGAGGAAGAGGAGGACATGGTCTCCGAGGAGGAGGAGG AGGAGGACGGCGACGCCGAGGAGACCCAGGATTCTGAGGACGACGAGGAGGATGAGATGGAAGAGGACGACGATGACTCCGATTATCCGGAGGAGATGGA AGACGACGACGACGACGCCAGTTACTGCACGGAAAGCAGCTTCAGGAGCCATAGTACCTACAGCAGCACTCCAGGTAGGCGAAAACCAAGAGTACATCGG CCTCGTTCTCCTATATTGGAAGAAAAAGACATCCCGCCCCTTGAATTTCCCAAGTCCTCTGAGGATTTAATGGTGCCTAATGAGCATATAATGAATGTCA TTGCCATTTACGAGGTACTGCGGAACTTTGGCACTGTTTTGAGATTATCTCCTTTTCGCTTTGAGGACTTTTGTGCAGCTCTGGTGAGCCAAGAGCAGTG CACACTCATGGCAGAGATGCATGTTGTGCTTTTGAAAGCAGTTCTGCGTGAAGAAGACACTTCCAATACTACCTTTGGACCTGCTGATCTGAAAGATAGC GTTAATTCCACACTGTATTTCATAGATGGGATGACGTGGCCAGAGGTGCTGCGGGTGTACTGTGAGAGTGATAAGGAGTACCATCACGTTCTTCCTTACC AAGAGGCAGAGGACTACCCATATGGACCAGTAGAGAACAAGATCAAAGTTCTACAGTTTCTAGTCGATCAGTTTCTTACAACAAATATTGCTCGAGAGGA ATTGATGTCTGAAGGGGTGATACAGTATGATGACCATTGTAGGGTTTGTCACAAACTTGGGGATTTGCTTTGCTGTGAGACATGTTCAGCAGTATACCAT TTGGAATGTGTGAAGCCACCTCTTGAGGAGGTGCCAGAGGACGAGTGGCAGTGTGAAGTCTGTGTAGCACACAAGGTGCCTGGTGTGACTGACTGTGTTG CTGAAATCCAAAAAAATAAACCATATATTCGACATGAACCTATTGGATATGATAGAAGTCGGAGGAAATACTGGTTCTTGAACCGAAGACTCATAATAGA AGAAGATACAGAAAATGAAAATGAAAAGAAAATTTGGTATTACAGCACAAAGGTCCAACTTGCAGAATTAATTGACTGTCTAGACAAAGATTATTGGGAA GCAGAACTCTGCAAAATTCTAGAAGAAATGCGTGAAGAAATCCACCGACACATGGACATAACTGAAGACCTGACCAATAAGGCTCGGGGCAGTAACAAAT CCTTTCTGGCGGCAGCTAATGAAGAAATTTTGGAATCCATAAGAGCCAAAAAGGGAGACATTGATAATGTTAAAAGCCCAGAAGAAACAGAAAAAGACAA GAATGAGACTGAGAATGACTCTAAAGATGCTGAGAAAAACAGAGAAGAATTTGAAGACCAGTCCCTTGAAAAAGACAGTGACGACAAAACACCAGATGAT GACCCTGAGCAAGGAAAATCTGAGGTAGGTGATTTCAAATCGGAGAAGTCCAACGGGGAGCTAAGTGAATCTCCTGGAGCTGGAAAAGGAGCATCTGGCT CAACTCGAATCATCACCAGATTGCGGAATCCAGATAGCAAACTTAGTCAGCTGAAGAGCCAGCAGGTGGCAGCCGCTGCACATGAAGCAAATAAATTATT TAAGGAGGGCAAAGAGGTACTGGTAGTTAACTCTCAAGGAGAAATTTCACGGTTGAGCACCAAAAAGGAAGTGATCATGAAAGGAAATATCAACAATTAT TTTAAATTGGGTCAAGAAGGGAAGTATCGCGTCTACCACAATCAATACTCCACCAATTCATTTGCTTTGAATAAGCACCAGCACAGAGAAGACCATGATA AGAGAAGGCATCTTGCACATAAGTTCTGTCTGACTCCAGCAGGAGAGTTCAAATGGAACGGTTCTGTCCATGGGTCCAAAGTTCTTACCATATCTACTCT GAGACTGACTATCACCCAATTAGAAAACAACATCCCTTCATCCTTTCTTCATCCCAACTGGGCATCACATAGGGCAAATTGGATCAAGGCAGTTCAGATG TGTAGCAAACCCAGAGAATTTGCATTGGCTTTAGCCATTTTGGAGTGTGCAGTTAAACCAGTTGTGATGCTACCAATATGGCGAGAATCTTTAGGACATA CCAGGTTACACCGGATGACATCAATTGAAAGAGAAGAAAAGGAGAAAGTCAAAAAAAAAGAGAAGAAACAGGAAGAAGAAGAAACGATGCAGCAAGCGAC ATGGGTAAAATACACATTTCCAGTTAAGCATCAGGTTTGGAAACAAAAAGGTGAAGAGTACAGAGTGACAGGATATGGTGGTTGGAGCTGGATTAGTAAA ACTCATGTTTATAGGTTTGTTCCTAAATTGCCAGGCAATACTAATGTGAATTACAGAAAGTCGTTAGAAGGAACCAAAAATAATATGGATGAAAATATGG ATGAGTCAGATAAAAGAAAATGTTCACGAAGTCCAAAAAAAATAAAAATAGAGCCTGATTCTGAAAAAGATGAGGTAAAAGGTTCAGATGCTGCAAAAGG AGCAGACCAAAATGAAATGGATATCTCAAAGATTACTGAGAAGAAGGACCAAGATGTGAAGGAGCTCTTAGATTCTGACAGTGATAAACCCTGCAAGGAA GAACCAATGGAAGTAGACGATGACATGAAAACAGAGTCACATGTAAATTGTCAGGAGAGTTCTCAAGTAGATGTGGTCAATGTTAGTGAGGGTTTTCATC TAAGGACTAGTTACAAAAAGAAAACAAAATCATCCAAACTAGATGGACTTCTTGAAAGGAGAATTAAACAGTTTACACTGGAAGAAAAACAGCGACTCGA AAAAATCAAGTTGGAGGGTGGAATTAAGGGTATAGGAAAGACTTCTACAAATTCTTCAAAAAATCTCTCTGAATCACCAGTAATAACGAAAGCAAAAGAA GGGTGTCAGAGTGACTCGATGAGACAAGAACAGAGCCCAAATGCAAATAATGATCAACCTGAGGACTTGATTCAGGGATGTTCAGAAAGTGATTCCTCAG TTCTTAGAATGAGTGATCCTAGTCATACCACAAACAAACTTTATCCAAAAGATCGAGTGTTAGATGATGTCTCCATTCGGAGCCCAGAAACAAAATGTCC GAAACAAAATTCCATTGAAAATGACATAGAAGAAAAAGTCTCTGACCTTGCCAGTAGAGGCCAGGAACCCAGTAAGAGTAAAACAAAAGGAAATGATTTT TTCATCGATGACTCTAAACTAGCCAGTGCAGATGATATTGGTACTTTGATCTGTAAGAACAAAAAACCGCTCATACAGGAGGAAAGTGACACCATTGTTT CTTCTTCCAAGAGTGCTTTACATTCATCAGTGCCTAAAAGTACCAATGACAGAGATGCCACACCTCTGTCAAGAGCAATGGACTTTGAAGGAAAACTGGG ATGTGACTCTGAATCTAATAGCACTTTGGAAAATAGTTCTGATACCGTGTCTATTCAGGATAGCAGTGAAGAAGATATGATTGTTCAGAATAGCAATGAA AGCATTTCTGAACAGTTCAGAACTCGAGAACAAGATGTTGAAGTCTTGGAGCCGTTAAAGTGTGAGTTGGTTTCTGGTGAGTCCACTGGAAACTGTGAGG ACAGGCTGCCGGTCAAGGGGACTGAAGCAAATGGTAAAAAACCAAGTCAGCAGAAGAAATTAGAGGAGAGACCAGTTAATAAATGTAGTGATCAAATAAA GCTAAAAAATACCACTGACAAAAAGAATAATGAAAATCGAGAGTCTGAAAAGAAAGGACAGAGAACAAGTACATTTCAAATAAATGGAAAAGATAATAAA CCCAAAATATATTTGAAAGGTGAATGCTTGAAAGAAATTTCTGAGAGTAGAGTAGTAAGTGGTAATGTTGAACCAAAGGTTAATAATATAAATAAAATAA TCCCTGAGAATGATATTAAATCATTGACTGTTAAAGAATCTGCTATAAGGCCATTCATTAATGGTGATGTCATCATGGAAGATTTTAATGAAAGAAACAG CTCCGAAACAAAATCGCATTTGCTGAGTTCTTCAGATGCTGAAGGTAACTACCGAGATAGCCTTGAGACCCTGCCATCAACCAAAGAGTCTGACAGTACA CAGACGACCACACCCTCAGCATCTTGTCCAGAAAGCAATTCAGTTAATCAGGTAGAAGATATGGAAATAGAAACCTCAGAAGTTAAGAAAGTTACTTCAT CACCTATTACTTCTGAAGAGGAATCTAATCTCAGTAATGACTTTATTGATGAAAATGGTCTGCCCATCAACAAAAATGAAAATGTCAATGGAGAATCTAA AAGAAAAACCGTCATCACAGAAGTCACCACGATGACCTCCACAGTGGCCACAGAATCAAAAACTGTGATCAAGGTAGAAAAAGGCGATAAGCAAACTGTG GTTTCTTCCACAGAAAATTGTGCAAAATCCACTGTCACAACCACCACTACAACAGTGACCAAGCTTTCCACACCCTCCACAGGCGGCAGTGTGGACATCA TCTCTGTAAAGGAGCAGAGCAAAACCGTGGTCACCACGACAGTGACAGACTCCCTGACCACCACGGGAGGCACACTGGTTACATCTATGACTGTGAGCAA AGAGTATTCCACACGAGACAAAGTGAAACTGATGAAATTTTCAAGACCAAAGAAGACTCGTTCAGGTACAGCTCTGCCATCCTATAGAAAATTTGTTACC AAGAGCAGCAAGAAGAGCATTTTTGTTTTGCCTAATGATGACTTAAAAAAGTTGGCCCGAAAAGGAGGAATCCGAGAGGTCCCTTATTTTAATTACAATG CAAAACCTGCTTTGGATATATGGCCATATCCTTCTCCTAGACCGACCTTTGGCATCACTTGGAGGTATAGACTTCAGACAGTAAAGTCCTTAGCTGGAGT GAGCCTGATGTTACGGTTACTGTGGGCAAGTTTGAGATGGGATGATATGGCGGCCAAGGCTCCTCCAGGAGGAGGGACTACACGGACAGAAACATCCGAA ACTGAAATCACAACAACAGAAATAATTAAGAGGAGAGATGTTGGTCCTTATGGCATTCGATCTGAATATTGTATCAGGAAAATCATTTGTCCCATTGGAG TTCCAGAAACACCAAAAGAAACGCCTACACCTCAGAGGAAAGGCCTTCGATCAAGTGCACTGCGGCCAAAGAGACCAGAAACGCCCAAGCAAACTGGCCC TGTTATTATTGAAACCTGGGTAGCAGAAGAAGAACTGGAATTGTGGGAGATCAGGGCATTTGCTGAGAGAGTGGAGAAAGAAAAGGCACAAGCAGTTGAG CAACAGGCTAAGAAACGACTGGAGCAGCAGAAGCCGACAGTGATTGCAACTTCCACTACTTCCCCAACAAGCAGTACAACCAGCACCATCTCTCCAGCAC AGAAGGTTATGGTGGCCCCCATAAGTGGCTCAGTTACAACTGGAACCAAAATGGTACTAACTACTAAAGTTGGATCTCCAGCTACAGTAACATTCCAACA AAACAAGAACTTTCATCAAACCTTTGCTACATGGGTTAAGCAAGGCCAGTCAAATTCAGGCGTTGTTCAAGTACAGCAGAAAGTCCTGGGTATCATTCCA TCAAGTACAGGTACCAGTCAGCAAACCTTTACTTCATTCCAGCCCAGGACAGCAACAGTCACAATTAGGCCCAATACCTCAGGCTCTGGAGGAACCACAA GCAATTCACAAGTAATCACAGGGCCTCAGATTCGCCCTGGTATGACCGTGATTAGAACACCACTCCAACAGTCAACACTAGGAAAGGCAATTATTCGAAC ACCTGTGATGGTACAGCCAGGTGCTCCTCAGCAAGTGATGACTCAAATCATCAGGGGGCAGCCTGTCTCCACTGCAGTCTCCGCCCCTAACACGGTTTCC TCAACACCTGGGCAGAAAAGCTTAACTTCAGCAACGTCCACTTCAAATATACAGTCTTCAGCCTCACAACCCCCTCGCCCCCAACAAGGACAAGTGAAGC TCACCATGGCTCAACTTACTCAGTTAACACAGGGCCACGGTGGCAATCAAGGTTTGACAGTAGTAATTCAAGGACAAGGTCAAACTACTGGACAGTTGCA GTTGATACCTCAAGGGGTGACTGTACTCCCAGGCCCAGGCCAGCAGCTAATGCAAGCTGCAATGCCAAATGGTACTGTTCAGCGATTCCTCTTTACCCCA TTGGCAACAACAGCCACCACAGCCAGCACCACCACCACCACTGTTTCCACGACAGCAGCAGGTACAGGTGAACAAAGGCAGAGTAAACTGTCACCCCAGA TGCAGGTACATCAAGACAAAACCCTGCCACCAGCTCAGTCATCAAGTGTGGGTCCAGCAGAAGCCCAGCCACAGACTGCTCAGCCTTCAGCTCAGCCCCA GCCCCAAACCCAGCCCCAGTCCCCAGCTCAGCCTGAAGTTCAGACTCAGCCTGAAGTTCAGACCCAAACAACTGTTTCATCCCATGTCCCTTCTGAAGCA CAACCCACCCACGCACAGTCATCCAAGCCCCAAGTTGCAGCACAGTCTCAGCCTCAAAGTAATGTCCAAGGACAGTCTCCTGTTCGTGTCCAAAGTCCAT CACAGACTCGAATACGTCCATCAACTCCATCCCAACTGTCTCCTGGACAACAATCCCAGGTTCAGACTACAACCTCACAACCGATTCCAATTCAACCACA TACATCTCTTCAGATACCTTCCCAAGGCCAGCCACAGTCACAACCCCAGGTACAGTCTTCAACTCAAACTCTTTCATCAGGACAAACTTTAAATCAAGTT ACTGTTTCATCCCCATCCCGTCCTCAGCTACAAATACAGCAGCCACAGCCCCAAGTCATTGCTGTGCCTCAGCTGCAACAACAAGTCCAGGTTCTCTCTC AGATCCAGTCACAGGTTGTGGCTCAGATACAGGCTCAGCAAAGTGGTGTGCCCCAGCAAATCAAACTCCAGTTACCTATCCAAATTCAGCAAAGCAGTGC TGTGCAGACTCACCAGATTCAGAATGTGGTTACAGTGCAGGCAGCCAGTGTGCAAGAGCAGTTGCAAAGGGTTCAGCAACTCAGGGATCAGCAGCAAAAG AAGAAACAGCAACAGATAGAAATTAAGCGTGAACACACCCTCCAAGCTTCTAATCAAAGTGAAATCATTCAGAAACAGGTGGTGATGAAGCATAATGCTG TAATAGAACATTTAAAACAGAAAAAGAGCATGACTCCAGCTGAAAGAGAAGAGAATCAAAGAATGATTGTCTGTAACCAGGTGATGAAGTATATTTTGGA TAAGATAGATAAAGAAGAAAAACAGGCAGCAAAAAAACGGAAGCGTGAAGAGAGTGTGGAGCAGAAACGTAGCAAGCAGAATGCCACTAAGCTGTCAGCT CTGCTCTTCAAGCACAAAGAGCAGCTCAGAGCCGAGATCCTGAAGAAGAGAGCACTCCTGGACAAGGATCTGCAAATTGAAGTGCAGGAAGAGCTGAAGA GAGACCTGAAAATTAAGAAAGAAAAAGACCTGATGCAGTTGGCTCAGGCCACAGCAGTAGCTGCACCCTGCCCCCCAGTGACACCAGCTCCTCCAGCCCC TCCAGCCCCTCCACCTTCACCTCCCCCTCCACCTGCTGTGCAACACACAGGCCTTCTGTCCACGCCCACCTTACCTGCTGCTTCCCAGAAGAGGAAGCGG GAAGAGGAAAAAGACTCCAGCTCAAAGTCCAAGAAAAAGAAAATGATCTCTACTACCTCAAAGGAAACTAAGAAGGACACAAAGCTTTACTGTATCTGTA AAACGCCTTATGATGAATCTAAATTTTATATTGGCTGTGATCGGTGTCAGAATTGGTACCATGGGCGCTGCGTTGGCATCTTGCAAAGTGAGGCAGAGCT CATTGATGAGTATGTCTGTCCACAGTGCCAGTCAACAGAGGATGCCATGACAGTGCTCACGCCACTAACAGAGAAGGATTATGAGGGGTTGAAGAGGGTG CTCCGTTCCTTACAGGCCCATAAGATGGCCTGGCCTTTCCTTGAACCAGTAGACCCTAATGATGCACCAGATTATTATGGTGTTATTAAGGAACCTATGG ACCTTGCCACCATGGAAGAAAGAGTACAAAGACGATATTATGAAAAGCTGACGGAATTTGTGGCAGATATGACCAAAATTTTTGATAACTGTCGTTACTA CAATCCAAGTGACTCCCCATTTTACCAGTGTGCAGAAGTTCTCGAATCATTCTTTGTACAGAAATTGAAAGGCTTCAAAGCTAGCAGGTCTCATAACAAC AAACTGCAGTCTACAGCTTCTTAAAGTTCAGCGTGTTAACCTAACATAAAACACAGCAAGAATCTGGTTGTCTGAACTATTTTAAATTAAGGAGCCAGAT GTTTTTAGTCAGGCTATCCTGACAAGACTTGACCTAAACTTCGTTTTTATTGGTCATAACAGTCCAATTATATTCTTGGCCAATTTTGTCCAACGGACAA GAAAAAAGCAAAGTCAACGACACCATTATCTTGTCAAGATCAGATGGTTTTACTATTGTGGCAGAAGCGAGAAAACTTTGTTTATTGAAAAAAAAAGAAA AAGAAAGCAAGAAAAAAAGATACTATGGGGTCAAGTGTAACTCCATGGAAATGCCACGTCTGCTCTTCAGTGAAGAAGCTGGTTTAGAGTCTCACAGAAA ACTTTTGACTGTATTTATTTATTGTTGCAAAAAAGACGCTTTTTTATTGCTGCCCTCATTTGTCAGCTAATTATTTTTTCTTATAAAATCCAGCCCCGGT TACATATAATCATCTGTATCTTATCATGATTCCTGTAGGTAAAAGTACAAGACGACCTCTAGATGTCTTTTCTTTCTATGAAAGGAGCTGCTATGTACAC ATGTGCACACACACACAACTGGGAATCAACAATGAGTTTATTGTTCATGGTAGATTAAAATTAAGCTTGCATAAAGGTTGGGCTAAGTGGTCCTGGACTA CAGACTCTGTTGCCTTGAATATAACAGTACAATTTGTCAATTACTCTGCACCAGGCTAAAATGAGTAAAATCTATTTGAAGGTATCTTGTTTGTAAACAT TTGTCAGATTCTAATTTTTTTCTTTTGTATTAAAATTCAACTATGGATGTATATGAAACAAAATAAATGGAGATAATTTTTCTCCCACAGACAGAGGTGT CTTTGAATGTGCGCTAATGATTATCTGTAAGCCTTTGTGGGGAGGGAGGCCTGCAAGGTCATGAAAGGCAGAAGAGTCTAATTGTGCCTGGATTTCTCCA GGACAGCAGTGGCCCCTCGTTTTATCATTCCCAGTCCATTGTCATCACGTCAGAGAAAAATCTTCAGGGGTGCTAATCCTGTTGCATCAGTTGATCATAC TAACGAGAACGGTAATGCGACAAGATACACATTGCCTTCATCTGTACATTCTGTGATACCAGGCAAATTACCAATTACACACAGCTACTTATATTTTATG AAGGGCATTTTTTAGATGACCTCATCCTCTGTGTTATTTGTTGATTGGGTTTGTTTTCTGTTTGTTGGTTTGTTTGTTTCTTCCACGTAAGGAAAAGTAG TGTAAACAGTAGCGAGAAAATGGAAACCACAGAGGAAGATGTATTTTGCATGTTTTTCCTTTCAGTGTTCTTACACGTTGTATCACTGCATTGTGGTAAT AGCTTCTATAAAATCTGCCATAGTTGGATTATGCAGCTTTGCAAAAATTTTTACTAGATTTTGCACTAACTCATATTAGCTTTGTCCTACCAACTTCTGG AATTTATCTAATTATTGTTTTTCAAAGTTTCTTTCCTTTTAATGTTTCCCTGCTATGCAAAACCTTTCCCAGACCTCAGTTTCTTAAAAGAAAGATGTTG CTACAGTTCCCGATTCTTTCTTATTACAGGCTCAGGTGTACAGGTTATTCTGGGTTAATTTTATCTAATGAAGCCCATTCCTTTTTGTACATAAAGATGT CACTTAAACTTATGCTTACAAACTAAAGACTAATCGCTCAATATGAAAACATGAAAAAATTTTTGCTTAAAGTATTAAGATGGAAGTAGTTAAATATGGG TTATTTTGTCCTTTTACTTTTTTAAAAAATGTTACATATTGTATGCACTGTGCTGATGCAAGAATTCTACATTTTAATGAGTTATAAAATTATTCTGCAT CTCATCACGTCACAGTATTTCTGTACTATTTATTCATATATATAAATATATATGGGCTTAATCATTTAAAATTTGTTGCAGCAAGAACTTTCCTACCTGT AGGCAATAGATTGCTATGTTTTTAACAAATTGTGGCAAATTCTAAACAGCAATTCTTTTGTACGTAATAGGACATTTCATCCTAGAAAAATAAAGTAATG TTTTTGACATTG

refseq_FALZ.F1 (forward primer)
refseq_FALZ.R1 (reverse primer)
Multiple exon skipping

Frame 0

RPPCARPSPFAFLLPPPRLRHEGPAGQAAQAAR GSRCGALRPGPAATAAAAHVRTHRGAPLAAPRQQ PGQVGRRPG*GGAQDAAELAQGGQQ*PEEAAAA AAGPPQHQRPGPGGARRRGRQDGGRGRRRPPGP DHRGPEGRQQSGVR*PRERGGGGRGGHGLRGGGG GGRRRRGDPGF*GRRGG*DGRGRR*LRLSGGDG RRRRRRQLLHGKQLQEP*YLQQHSR*AKTKSTS ASFSYIGRKRHPAP*ISQVL*GFNGA**AYNECH CHLRGTAELWHCFEIISFSL*GLLCSSGEPRAV HTHGRDACCAFESSSA*RRHFQYYLWTC*SER* R*FHTVFHRWDDVARGAAGVL*E**GVPSRSSLP RGRGLPIWTSREQDQSSTVSSRSVSYNKYCSRG IDV*RGDTV**PL*GLSQTWGFALL*DMFSSIP FGMCEATS*GGARGRVAV*SLCSTQGAWCD*LCC *NPKK*TIYST*TYWI**KSEEILVLEPKTHNR RRYRK*K*KENLVLQHKGPTCRIN*LSRQRLLG SRTLQNSRRNA*RNPPTHGHN*RPDQ*GSGQ*QI LSGGS**RNFGIHKSQKGRH**C*KPRRNRKRQ E*D*E*L*RC*EKQRRI*RPVP*KRQ*RQNTR* *P*ARKI*GR*FQIGEVQRGAK*ISWSWKRSIWL NSNHHQIAESR*QT*SAEEPAGGSRCT*SK*II *GGQRGTGS*LSRRNFTVEHQKGSDHERKYQQL F*IGSRREVSRLPQSILHQFICFE*APAQRRP** EKASCT*VLSDSSRRVQMERFCPWVQSSYHIYS ETDYHPIRKQHPFILSSSQLGIT*GKLDQGSSD V*QTQRICIGFSHFGVCS*TSCDATNMARIFRTY QVTPDDIN*KRRKGESQKKREETGRRRNDAASD MGKIHISS*ASGLETKR*RVQSDRIWWLELD** NSCL*VCS*IARQY*CELQKVVRRNQK*YG*KYG *VR*KKMFTKSKKNKNRA*F*KR*GKRFRCCKR SRPK*NGYLKDY*EEGPRCEGALRF*Q**TLQG RTNGSRR*HENRVTCKLSGEFSSRCGQC**GFSS KD*LQKENKIIQTRWTS*KEN*TVYTGRKTATR KNQVGGWN*GYRKDFYKFFKKSL*ITSNNESKR RVSE*LDETRTEPKCK**ST*GLDSGMFRK*FLS S*NE*S*SYHKQTLSKRSSVR*CLHSEPRNKMS ETKFH*K*HRRKSL*PCQ*RPGTQ*E*NKRK*F FHR*L*TSQCR*YWYFDL*EQKTAHTGGK*HHCF FFQECFTFISA*KYQ*QRCHTSVKSNGL*RKTG M*L*I**HFGK*F*YRVYSG*Q*RRYDCSE*Q* KHF*TVQNSRTRC*SLGAVKV*VGFW*VHWKL*G QAAGQGD*SKW*KTKSAEEIRGETS**M**SNK AKKYH*QKE**KSRV*KERTENKYISNKWKR** TQNIFER*MLERNF*E*SSKW*C*TKG**YK*NN P*E*Y*IIDC*RICYKAIH*W*CHHGRF**KKQ LRNKIAFAEFFRC*R*LPR*P*DPAINQRV*QY TDDHTLSILSRKQFS*SGRRYGNRNLRS*ESYFI TYYF*RGI*SQ**LY**KWSAHQQK*KCQWRI* KKNRHHRSHHDDLHSGHRIKNCDQGRKRR*ANC GFFHRKLCKIHCHNHHYNSDQAFHTLHRRQCGHH LCKGAEQNRGHHDSDRLPDHHGRHTGYIYDCEQ RVFHTRQSETDEIFKTKEDSFRYSSAIL*KICY QEQQEEHFCFA***LKKVGPKRRNPRGPLF*LQC KTCFGYMAISFS*TDLWHHLEV*TSDSKVLSWS EPDVTVTVGKFEMG*YGGQGSSRRRDYTDRNIR N*NHNNRNN*EERCWSLWHSI*ILYQENHLSHWS SRNTKRNAYTSEERPSIKCTAAKETRNAQANWP CYY*NLGSRRRTGIVGDQGIC*ESGERKGTSS* ATG*ETTGAAEADSDCNFHYFPNKQYNQHHLSST EGYGGPHKWLSYNWNQNGTNY*SWISSYSNIPT KQELSSNLCYMG*ARPVKFRRCSSTAESPGYHS IKYRYQSANLYFIPAQDSNSHN*AQYLRLWRNHK QFTSNHRASDSPWYDRD*NTTPTVNTRKGNYSN TCDGTARCSSASDDSNHQGAACLHCSLRP*HGF LNTWAEKLNFSNVHFKYTVFSLTTPSPPTRTSEA HHGSTYSVNTGPRWQSRFDSSNSRTRSNYWTVA VDTSRGDCTPRPRPAANASCNAKWYCSAIPLYP IGNNSHHSQHHHHHCFHDSSRYR*TKAE*TVTPD AGTSRQNPATSSVIKCGSSRSPATDCSAFSSAP APNPAPVPSSA*SSDSA*SSDPNNCFIPCPF*S TTHPRTVIQAPSCSTVSASK*CPRTVSCSCPKSI TDSNTSINSIPTVSWTTIPGSDYNLTTDSNSTT YISSDTFPRPATVTTPGTVFNSNSFIRTNFKSS YCFIPIPSSATNTAATAPSHCCASAATTSPGSLS DPVTGCGSDTGSAKWCAPANQTPVTYPNSAKQC CADSPDSECGYSAGSQCARAVAKGSATQGSAAK EETATDRN*A*THPPSF*SK*NHSETGGDEA*CC NRTFKTEKEHDSS*KRRESKNDCL*PGDEVYFG *DR*RRKTGSKKTEA*RECGAET*QAECH*AVS SALQAQRAAQSRDPEEESTPGQGSAN*SAGRAEE RPEN*ERKRPDAVGSGHSSSCTLPPSDTSSSSP SSPSTFTSPSTCCATHRPSVHAHLTCCFPEEEA GRGKRLQLKVQEKENDLYYLKGN*EGHKALLYL* NAL**I*ILYWL*SVSELVPWALRWHLAK*GRA H**VCLSTVPVNRGCHDSAHATNREGL*GVEEG APFLTGP*DGLAFP*TSRP**CTRLLWCY*GTYG PCHHGRKSTKTIL*KADGICGRYDQNF**LSLL QSK*LPILPVCRSSRIILCTEIERLQS*QVS*Q QTAVYSFLKFSVLT*HKTQQESGCLNYFKLRSQM FLVRLS*QDLT*TSFLLVITVQLYSWPILSNGQ EKSKVNDTIILSRSDGFTIVAEARKLCLLKKKE KESKKKRYYGVKCNSMEMPRLLFSEEAGLESHRK LLTVFIYCCKKDAFLLLPSFVS*LFFLIKSSPG YI*SSVSYHDSCR*KYKTTSRCLFFL*KELLCT HVHTHTTGNQQ*VYCSW*IKIKLA*RLG*VVLDY RLCCLEYNSTICQLLCTRLK*VKSI*RYLVCKH LSDSNFFLLY*NSTMDVYETK*MEIIFLPQTEV SLNVR**LSVSLCGEGGLQGHERQKSLIVPGFLQ DSSGPSFYHSQSIVITSEKNLQGC*SCCIS*SY *RER*CDKIHIAFICTFCDTRQITNYTQLLIFY EGHFLDDLILCVIC*LGLFSVCWFVCFFHVRKSS VNSSEKMETTEEDVFCMFFLSVFLHVVSLHCGN SFYKICHSWIMQLCKNFY*ILH*LILALSYQLL EFI*LLFFKVSFLLMFPCYAKPFPDLSFLKERCC YSSRFFLITGSGVQVILG*FYLMKPIPFCT*RC HLNLCLQTKD*SLNMKT*KNFCLKY*DGSS*IW VILSFYFFKKCYILYALC*CKNSTF**VIKLFCI SSRHSISVLFIHIYKYIWA*SFKICCSKNFPTC RQ*IAMFLTNCGKF*TAILLYVIGHFILEK*SN VFDI

Frame 1

APPAPAPPPSLSFSPRLGSDMRGRRGRPPKQPA APAAERCAPAPPPPPPPPTSGPIGGLRSRHRGS SRGRWAAAQAEVAPKTRLSSPRGGSSSRRKPPPP PPAPPSTSAPGRGGRGGGGGRTGGGGGGGHLAR TTAARRAVNKVVYDDHESEEEEEEEDMVSEEEE EEDGDAEETQDSEDDEEDEMEEDDDDSDYPEEME DDDDDASYCTESSFRSHSTYSSTPGRRKPRVHR PRSPILEEKDIPPLEFPKSSEDLMVPNEHIMNV IAIYEVLRNFGTVLRLSPFRFEDFCAALVSQEQC TLMAEMHVVLLKAVLREEDTSNTTFGPADLKDS VNSTLYFIDGMTWPEVLRVYCESDKEYHHVLPY QEAEDYPYGPVENKIKVLQFLVDQFLTTNIAREE LMSEGVIQYDDHCRVCHKLGDLLCCETCSAVYH LECVKPPLEEVPEDEWQCEVCVAHKVPGVTDCV AEIQKNKPYIRHEPIGYDRSRRKYWFLNRRLIIE EDTENENEKKIWYYSTKVQLAELIDCLDKDYWE AELCKILEEMREEIHRHMDITEDLTNKARGSNK SFLAAANEEILESIRAKKGDIDNVKSPEETEKDK NETENDSKDAEKNREEFEDQSLEKDSDDKTPDD DPEQGKSEVGDFKSEKSNGELSESPGAGKGASG STRIITRLRNPDSKLSQLKSQQVAAAAHEANKLF KEGKEVLVVNSQGEISRLSTKKEVIMKGNINNY FKLGQEGKYRVYHNQYSTNSFALNKHQHREDHD KRRHLAHKFCLTPAGEFKWNGSVHGSKVLTISTL RLTITQLENNIPSSFLHPNWASHRANWIKAVQM CSKPREFALALAILECAVKPVVMLPIWRESLGH TRLHRMTSIEREEKEKVKKKEKKQEEEETMQQAT WVKYTFPVKHQVWKQKGEEYRVTGYGGWSWISK THVYRFVPKLPGNTNVNYRKSLEGTKNNMDENM DESDKRKCSRSPKKIKIEPDSEKDEVKGSDAAKG ADQNEMDISKITEKKDQDVKELLDSDSDKPCKE EPMEVDDDMKTESHVNCQESSQVDVVNVSEGFH LRTSYKKKTKSSKLDGLLERRIKQFTLEEKQRLE KIKLEGGIKGIGKTSTNSSKNLSESPVITKAKE GCQSDSMRQEQSPNANNDQPEDLIQGCSESDSS VLRMSDPSHTTNKLYPKDRVLDDVSIRSPETKCP KQNSIENDIEEKVSDLASRGQEPSKSKTKGNDF FIDDSKLASADDIGTLICKNKKPLIQEESDTIV SSSKSALHSSVPKSTNDRDATPLSRAMDFEGKLG CDSESNSTLENSSDTVSIQDSSEEDMIVQNSNE SISEQFRTREQDVEVLEPLKCELVSGESTGNCE DRLPVKGTEANGKKPSQQKKLEERPVNKCSDQIK LKNTTDKKNNENRESEKKGQRTSTFQINGKDNK PKIYLKGECLKEISESRVVSGNVEPKVNNINKI IPENDIKSLTVKESAIRPFINGDVIMEDFNERNS SETKSHLLSSSDAEGNYRDSLETLPSTKESDST QTTTPSASCPESNSVNQVEDMEIETSEVKKVTS SPITSEEESNLSNDFIDENGLPINKNENVNGESK RKTVITEVTTMTSTVATESKTVIKVEKGDKQTV VSSTENCAKSTVTTTTTTVTKLSTPSTGGSVDI ISVKEQSKTVVTTTVTDSLTTTGGTLVTSMTVSK EYSTRDKVKLMKFSRPKKTRSGTALPSYRKFVT KSSKKSIFVLPNDDLKKLARKGGIREVPYFNYN AKPALDIWPYPSPRPTFGITWRYRLQTVKSLAGV SLMLRLLWASLRWDDMAAKAPPGGGTTRTETSE TEITTTEIIKRRDVGPYGIRSEYCIRKIICPIG VPETPKETPTPQRKGLRSSALRPKRPETPKQTGP VIIETWVAEEELELWEIRAFAERVEKEKAQAVE QQAKKRLEQQKPTVIATSTTSPTSSTTSTISPA QKVMVAPISGSVTTGTKMVLTTKVGSPATVTFQQ NKNFHQTFATWVKQGQSNSGVVQVQQKVLGIIP SSTGTSQQTFTSFQPRTATVTIRPNTSGSGGTT SNSQVITGPQIRPGMTVIRTPLQQSTLGKAIIRT PVMVQPGAPQQVMTQIIRGQPVSTAVSAPNTVS STPGQKSLTSATSTSNIQSSASQPPRPQQGQVK LTMAQLTQLTQGHGGNQGLTVVIQGQGQTTGQLQ LIPQGVTVLPGPGQQLMQAAMPNGTVQRFLFTP LATTATTASTTTTTVSTTAAGTGEQRQSKLSPQ MQVHQDKTLPPAQSSSVGPAEAQPQTAQPSAQPQ PQTQPQSPAQPEVQTQPEVQTQTTVSSHVPSEA QPTHAQSSKPQVAAQSQPQSNVQGQSPVRVQSP SQTRIRPSTPSQLSPGQQSQVQTTTSQPIPIQPH TSLQIPSQGQPQSQPQVQSSTQTLSSGQTLNQV TVSSPSRPQLQIQQPQPQVIAVPQLQQQVQVLS QIQSQVVAQIQAQQSGVPQQIKLQLPIQIQQSSA VQTHQIQNVVTVQAASVQEQLQRVQQLRDQQQK KKQQQIEIKREHTLQASNQSEIIQKQVVMKHNA VIEHLKQKKSMTPAEREENQRMIVCNQVMKYILD KIDKEEKQAAKKRKREESVEQKRSKQNATKLSA LLFKHKEQLRAEILKKRALLDKDLQIEVQEELK RDLKIKKEKDLMQLAQATAVAAPCPPVTPAPPAP PAPPPSPPPPPAVQHTGLLSTPTLPAASQKRKR EEEKDSSSKSKKKKMISTTSKETKKDTKLYCIC KTPYDESKFYIGCDRCQNWYHGRCVGILQSEAEL IDEYVCPQCQSTEDAMTVLTPLTEKDYEGLKRV LRSLQAHKMAWPFLEPVDPNDAPDYYGVIKEPM DLATMEERVQRRYYEKLTEFVADMTKIFDNCRYY NPSDSPFYQCAEVLESFFVQKLKGFKASRSHNN KLQSTAS*SSAC*PNIKHSKNLVV*TILN*GAR CF*SGYPDKT*PKLRFYWS*QSNYILGQFCPTDK KKAKSTTPLSCQDQMVLLLWQKRENFVY*KKKK KKARKKDTMGSSVTPWKCHVCSSVKKLV*SLTE NF*LYLFIVAKKTLFYCCPHLSANYFFL*NPAPV TYNHLYLIMIPVGKSTRRPLDVFSFYERSCYVH MCTHTQLGINNEFIVHGRLKLSLHKGWAKWSWT TDSVALNITVQFVNYSAPG*NE*NLFEGILFVNI CQILIFFFCIKIQLWMYMKQNKWR*FFSHRQRC L*MCANDYL*AFVGREACKVMKGRRV*LCLDFS RTAVAPRFIIPSPLSSRQRKIFRGANPVASVDHT NENGNATRYTLPSSVHSVIPGKLPITHSYLYFM KGIF*MTSSSVLFVDWVCFLFVGLFVSST*GKV V*TVARKWKPQRKMYFACFSFQCSYTLYHCIVVI ASIKSAIVGLCSFAKIFTRFCTNSY*LCPTNFW NLSNYCFSKFLSF*CFPAMQNLSQTSVS*KKDV ATVPDSFLLQAQVYRLFWVNFI**SPFLFVHKDV T*TYAYKLKTNRSI*KHEKIFA*SIKMEVVKYG LFCPFTFLKNVTYCMHCADARILHFNEL*NYSA SHHVTVFLYYLFIYINIYGLNHLKFVAARTFLPV GNRLLCF*QIVANSKQQFFCT**DISS*KNKVM FLTL

Frame 2

PPLRPPLPLRFPSPPASAPT*GAGGAGRPSSPR LPLRSAAPRPRRHRRRRPRPDPSGGSARGTAAA AGAGGPPPRLRWRPRRG*ARPGGAAVAGGSRRR RRRPPPAPAPRAGGGEEAGAAGRGAGAAAATWPG PPRPGGPSTKWCTMTTRARRRRKRRTWSPRRRR RRTATPRRPRILRTTRRMRWKRTTMTPIIRRRW KTTTTTPVTARKAASGAIVPTAALQVGENQEYIG LVLLYWKKKTSRPLNFPSPLRI*WCLMSI**MS LPFTRYCGTLALF*DYLLFALRTFVQLW*AKSS AHSWQRCMLCF*KQFCVKKTLPILPLDLLI*KIA LIPHCIS*MG*RGQRCCGCTVRVIRSTITFFLT KRQRTTHMDQ*RTRSKFYSF*SISFLQQILLER N*CLKG*YSMMTIVGFVTNLGICFAVRHVQQYTI WNV*SHLLRRCQRTSGSVKSV*HTRCLV*LTVL LKSKKINHIFDMNLLDMIEVGGNTGS*TEDS** KKIQKMKMKRKFGITAQRSNLQN*LTV*TKIIGK QNSAKF*KKCVKKSTDTWT*LKT*PIRLGAVTN PFWRQLMKKFWNP*EPKRETLIMLKAQKKQKKT RMRLRMTLKMLRKTEKNLKTSPLKKTVTTKHQMM TLSKENLR*VISNRRSPTGS*VNLLELEKEHLA QLESSPDCGIQIANLVS*RASRWQPLHMKQINY LRRAKRYW*LTLKEKFHG*APKRK*S*KEISTII LNWVKKGSIASTTINTPPIHLL*ISTSTEKTMI REGILHISSV*LQQESSNGTVLSMGPKFLPYLL *D*LSPN*KTTSLHPFFIPTGHHIGQIGSRQFRC VANPENLHWL*PFWSVQLNQL*CYQYGENL*DI PGYTG*HQLKEKKRRKSKKKRRNRKKKKRCSKR HG*NTHFQLSIRFGNKKVKSTE*QDMVVGAGLVK LMFIGLFLNCQAILM*ITESR*KEPKIIWMKIW MSQIKENVHEVQKK*K*SLILKKMR*KVQMLQK EQTKMKWISQRLLRRRTKM*RSS*ILTVINPARK NQWK*TMT*KQSHM*IVRRVLK*MWSMLVRVFI *GLVTKRKQNHPN*MDFLKGELNSLHWKKNSDS KKSSWRVELRV*ERLLQILQKISLNHQ**RKQKK GVRVTR*DKNRAQMQIMINLRT*FRDVQKVIPQ FLE*VILVIPQTNFIQKIEC*MMSPFGAQKQNV RNKIPLKMT*KKKSLTLPVEARNPVRVKQKEMIF SSMTLN*PVQMILVL*SVRTKNRSYRRKVTPLF LLPRVLYIHQCLKVPMTEMPHLCQEQWTLKENW DVTLNLIALWKIVLIPCLFRIAVKKI*LFRIAMK AFLNSSELENKMLKSWSR*SVSWFLVSPLETVR TGCRSRGLKQMVKNQVSRRN*RRDQLINVVIK* S*KIPLTKRIMKIESLKRKDREQVHFK*MEKIIN PKYI*KVNA*KKFLRVE**VVMLNQRLII*IK* SLRMILNH*LLKNLL*GHSLMVMSSWKILMKET APKQNRIC*VLQMLKVTTEIALRPCHQPKSLTVH RRPHPQHLVQKAIQLIR*KIWK*KPQKLRKLLH HLLLLKRNLISVMTLLMKMVCPSTKMKMSMENL KEKPSSQKSPR*PPQWPQNQKL*SR*KKAISKLW FLPQKIVQNPLSQPPLQQ*PSFPHPPQAAVWTS SL*RSRAKPWSPRQ*QTP*PPREAHWLHL*L*A KSIPHETK*N**NFQDQRRLVQVQLCHPIENLLP RAARRAFLFCLMMT*KSWPEKEESERSLILITM QNLLWIYGHILLLDRPLASLGGIDFRQ*SP*LE *A*CYGYCGQV*DGMIWRPRLLQEEGLHGQKHPK LKSQQQK*LRGEMLVLMAFDLNIVSGKSFVPLE FQKHQKKRLHLRGKAFDQVHCGQRDQKRPSKLA LLLLKPG*QKKNWNCGRSGHLLREWRKKRHKQLS NRLRNDWSSRSRQ*LQLPLLPQQAVQPAPSLQH RRLWWPP*VAQLQLEPKWY*LLKLDLQLQ*HSN KTRTFIKPLLHGLSKASQIQALFKYSRKSWVSFH QVQVPVSKPLLHSSPGQQQSQLGPIPQALEEPQ AIHK*SQGLRFALV*P*LEHHSNSQH*ERQLFE HL*WYSQVLLSK**LKSSGGSLSPLQSPPLTRFP QHLGRKA*LQQRPLQIYSLQPHNPLAPNKDK*S SPWLNLLS*HRATVAIKV*Q**FKDKVKLLDSC S*YLKG*LYSQAQASS*CKLQCQMVLFSDSSLPH WQQQPPQPAPPPPLFPRQQQVQVNKGRVNCHPR CRYIKTKPCHQLSHQVWVQQKPSHRLLSLQLSP SPKPSPSPQLSLKFRLSLKFRPKQLFHPMSLLKH NPPTHSHPSPKLQHSLSLKVMSKDSLLFVSKVH HRLEYVHQLHPNCLLDNNPRFRLQPHNRFQFNH IHLFRYLPKASHSHNPRYSLQLKLFHQDKL*IKL LFHPHPVLSYKYSSHSPKSLLCLSCNNKSRFSL RSSHRLWLRYRLSKVVCPSKSNSSYLSKFSKAV LCRLTRFRMWLQCRQPVCKSSCKGFSNSGISSKR RNSNR*KLSVNTPSKLLIKVKSFRNRW**SIML **NI*NRKRA*LQLKEKRIKE*LSVTR**SIFW IR*IKKKNRQQKNGSVKRVWSRNVASRMPLSCQL CSSSTKSSSEPRS*RREHSWTRICKLKCRKS*R ET*KLRKKKT*CSWLRPQQ*LHPAPQ*HQLLQP LQPLHLHLPLHLLCNTQAFCPRPPYLLLPRRGSG KRKKTPAQSPRKRK*SLLPQRKLRRTQSFTVSV KRLMMNLNFILAVIGVRIGTMGAALASCKVRQS SLMSMSVHSASQQRMP*QCSRH*QRRIMRG*RGC SVPYRPIRWPGLSLNQ*TLMMHQIIMVLLRNLW TLPPWKKEYKDDIMKS*RNLWQI*PKFLITVVT TIQVTPHFTSVQKFSNHSLYRN*KASKLAGLITT NCSLQLLKVQRVNLT*NTARIWLSELF*IKEPD VFSQAILTRLDLNFVFIGHNSPIIFLANFVQRT RKKQSQRHHYLVKIRWFYYCGRSEKTLFIEKKRK RKQEKKILWGQV*LHGNATSALQ*RSWFRVSQK TFDCIYLLLQKRRFFIAALICQLIIFSYKIQPR LHIIICILS*FL*VKVQDDL*MSFLSMKGAAMYT CAHTHNWESTMSLLFMVD*N*ACIKVGLSGPGL QTLLP*I*QYNLSITLHQAKMSKIYLKVSCL*T FVRF*FFSFVLKFNYGCI*NKINGDNFSPTDRGV FECALMIICKPLWGGRPARS*KAEESNCAWISP GQQWPLVLSFPVHCHHVREKSSGVLILLHQLII LTRTVMRQDTHCLHLYIL*YQANYQLHTATYIL* RAFFR*PHPLCYLLIGFVFCLLVCLFLPRKEK* CKQ*RENGNHRGRCILHVFPFSVLTRCITALW* *LL*NLP*LDYAALQKFLLDFALTHISFVLPTSG IYLIIVFQSFFPFNVSLLCKTFPRPQFLKRKML LQFPILSYYRLRCTGYSGLILSNEAHSFLYIKM SLKLMLTN*RLIAQYENMKKFLLKVLRWK*LNMG YFVLLLF*KMLHIVCTVLMQEFYILMSYKIILH LITSQYFCTIYSYI*IYMGLII*NLLQQELSYL *AIDCYVFNKLWQILNSNSFVRNRTFHPRKIK*C F*H

Sequence NM_004459

CGCCCCCCCTGCGCCCGCCCCTCCCCCTTCGCTTTCCTTCTCCCCCCGCCTCGGCTCCGACATGAGGGGCCGGCGGGGCAGGCCGCCCAAGCAGCCCGCG GCTCCCGCTGCGGAGCGCTGCGCCCCGGCCCCGCCGCCACCGCCGCCGCCGCCCACGTCCGGACCCATCGGGGGGCTCCGCTCGCGGCACCGCGGCAGCA GCCGGGGCAGGTGGGCCGCCGCCCAGGCTGAGGTGGCGCCCAAGACGCGGCTGAGCTCGCCCAGGGGGGGCAGCAGTAGCCGGAGGAAGCCGCCGCCGCC GCCGCCGGCCCCCCCCAGCACCAGCGCCCCGGGCCGGGGGGGGCGAGGAGGCGGGGGCGGCAGGACGGGGGGCGGGGGCGGCGGCGGCCACCTGGCCCGG ACCACCGCGGCCCGGAGGGCCGTCAACAAAGTGGTGTACGATGACCACGAGAGCGAGGAGGAGGAGGAAGAGGAGGACATGGTCTCCGAGGAGGAGGAGG AGGAGGACGGCGACGCCGAGGAGACCCAGGATTCTGAGGACGACGAGGAGGATGAGATGGAAGAGGACGACGATGACTCCGATTATCCGGAGGAGATGGA AGACGACGACGACGACGCCAGTTACTGCACGGAAAGCAGCTTCAGGAGCCATAGTACCTACAGCAGCACTCCAGGTAGGCGAAAACCAAGAGTACATCGG CCTCGTTCTCCTATATTGGAAGAAAAAGACATCCCGCCCCTTGAATTTCCCAAGTCCTCTGAGGATTTAATGGTGCCTAATGAGCATATAATGAATGTCA TTGCCATTTACGAGGTACTGCGGAACTTTGGCACTGTTTTGAGATTATCTCCTTTTCGCTTTGAGGACTTTTGTGCAGCTCTGGTGAGCCAAGAGCAGTG CACACTCATGGCAGAGATGCATGTTGTGCTTTTGAAAGCAGTTCTGCGTGAAGAAGACACTTCCAATACTACCTTTGGACCTGCTGATCTGAAAGATAGC GTTAATTCCACACTGTATTTCATAGATGGGATGACGTGGCCAGAGGTGCTGCGGGTGTACTGTGAGAGTGATAAGGAGTACCATCACGTTCTTCCTTACC AAGAGGCAGAGGACTACCCATATGGACCAGTAGAGAACAAGATCAAAGTTCTACAGTTTCTAGTCGATCAGTTTCTTACAACAAATATTGCTCGAGAGGA ATTGATGTCTGAAGGGGTGATACAGTATGATGACCATTGTAGGGTTTGTCACAAACTTGGGGATTTGCTTTGCTGTGAGACATGTTCAGCAGTATACCAT TTGGAATGTGTGAAGCCACCTCTTGAGGAGGTGCCAGAGGACGAGTGGCAGTGTGAAGTCTGTGTAGCACACAAGGTGCCTGGTGTGACTGACTGTGTTG CTGAAATCCAAAAAAATAAACCATATATTCGACATGAACCTATTGGATATGATAGAAGTCGGAGGAAATACTGGTTCTTGAACCGAAGACTCATAATAGA AGAAGATACAGAAAATGAAAATGAAAAGAAAATTTGGTATTACAGCACAAAGGTCCAACTTGCAGAATTAATTGACTGTCTAGACAAAGATTATTGGGAA GCAGAACTCTGCAAAATTCTAGAAGAAATGCGTGAAGAAATCCACCGACACATGGACATAACTGAAGACCTGACCAATAAGGCTCGGGGCAGTAACAAAT CCTTTCTGGCGGCAGCTAATGAAGAAATTTTGGAATCCATAAGAGCCAAAAAGGGAGACATTGATAATGTTAAAAGCCCAGAAGAAACAGAAAAAGACAA GAATGAGACTGAGAATGACTCTAAAGATGCTGAGAAAAACAGAGAAGAATTTGAAGACCAGTCCCTTGAAAAAGACAGTGACGACAAAACACCAGATGAT GACCCTGAGCAAGGAAAATCTGAGGAGCCAACAGAAGTTGGGGATAAAGGTAACTCTGTGTCAGCAAATCTTGGCGACAACACAACAAATGCAACTTCAG AAGAGACTAGTCCCTCTGAAGGGAGGAGCCCTGTGGGGTGTCTCTCAGAAACCCCCGATAGCAGCAACATGGCAGAGAAGAAGGTGGCATCTGAGCTCCC CCAGGATGTGCCAGAAGAACCTAACAAGACATGTGAGAGCAGTAACACTAGTGCTACCACTACCTCCATCCAGCCTAATCTGGAAAACAGTAACAGCAGC AGTGAACTAAATTCTTCCCAGAGTGAATCTGCTAAGGCAGCTGATGATCCTGAAAATGGAGAAAGAGAATCTCATACACCTGTCTCTATTCAGGAAGAGA TAGTAGGTGATTTCAAATCGGAGAAGTCCAACGGGGAGCTAAGTGAATCTCCTGGAGCTGGAAAAGGAGCATCTGGCTCAACTCGAATCATCACCAGATT GCGGAATCCAGATAGCAAACTTAGTCAGCTGAAGAGCCAGCAGGTGGCAGCCGCTGCACATGAAGCAAATAAATTATTTAAGGAGGGCAAAGAGGTACTG GTAGTTAACTCTCAAGGAGAAATTTCACGGTTGAGCACCAAAAAGGAAGTGATCATGAAAGGAAATATCAACAATTATTTTAAATTGGGTCAAGAAGGGA AGTATCGCGTCTACCACAATCAATACTCCACCAATTCATTTGCTTTGAATAAGCACCAGCACAGAGAAGACCATGATAAGAGAAGGCATCTTGCACATAA GTTCTGTCTGACTCCAGCAGGAGAGTTCAAATGGAACGGTTCTGTCCATGGGTCCAAAGTTCTTACCATATCTACTCTGAGACTGACTATCACCCAATTA GAAAACAACATCCCTTCATCCTTTCTTCATCCCAACTGGGCATCACATAGGGCAAATTGGATCAAGGCAGTTCAGATGTGTAGCAAACCCAGAGAATTTG CATTGGCTTTAGCCATTTTGGAGTGTGCAGTTAAACCAGTTGTGATGCTACCAATATGGCGAGAATCTTTAGGACATACCAGGTTACACCGGATGACATC AATTGAAAGAGAAGAAAAGGAGAAAGTCAAAAAAAAAGAGAAGAAACAGGAAGAAGAAGAAACGATGCAGCAAGCGACATGGGTAAAATACACATTTCCA GTTAAGCATCAGGTTTGGAAACAAAAAGGTGAAGAGTACAGAGTGACAGGATATGGTGGTTGGAGCTGGATTAGTAAAACTCATGTTTATAGGTTTGTTC CTAAATTGCCAGGCAATACTAATGTGAATTACAGAAAGTCGTTAGAAGGAACCAAAAATAATATGGATGAAAATATGGATGAGTCAGATAAAAGAAAATG TTCACGAAGTCCAAAAAAAATAAAAATAGAGCCTGATTCTGAAAAAGATGAGGTAAAAGGTTCAGATGCTGCAAAAGGAGCAGACCAAAATGAAATGGAT ATCTCAAAGATTACTGAGAAGAAGGACCAAGATGTGAAGGAGCTCTTAGATTCTGACAGTGATAAACCCTGCAAGGAAGAACCAATGGAAGTAGACGATG ACATGAAAACAGAGTCACATGTAAATTGTCAGGAGAGTTCTCAAGTAGATGTGGTCAATGTTAGTGAGGGTTTTCATCTAAGGACTAGTTACAAAAAGAA AACAAAATCATCCAAACTAGATGGACTTCTTGAAAGGAGAATTAAACAGTTTACACTGGAAGAAAAACAGCGACTCGAAAAAATCAAGTTGGAGGGTGGA ATTAAGGGTATAGGAAAGACTTCTACAAATTCTTCAAAAAATCTCTCTGAATCACCAGTAATAACGAAAGCAAAAGAAGGGTGTCAGAGTGACTCGATGA GACAAGAACAGAGCCCAAATGCAAATAATGATCAACCTGAGGACTTGATTCAGGGATGTTCAGAAAGTGATTCCTCAGTTCTTAGAATGAGTGATCCTAG TCATACCACAAACAAACTTTATCCAAAAGATCGAGTGTTAGATGATGTCTCCATTCGGAGCCCAGAAACAAAATGTCCGAAACAAAATTCCATTGAAAAT GACATAGAAGAAAAAGTCTCTGACCTTGCCAGTAGAGGCCAGGAACCCAGTAAGAGTAAAACAAAAGGAAATGATTTTTTCATCGATGACTCTAAACTAG CCAGTGCAGATGATATTGGTACTTTGATCTGTAAGAACAAAAAACCGCTCATACAGGAGGAAAGTGACACCATTGTTTCTTCTTCCAAGAGTGCTTTACA TTCATCAGTGCCTAAAAGTACCAATGACAGAGATGCCACACCTCTGTCAAGAGCAATGGACTTTGAAGGAAAACTGGGATGTGACTCTGAATCTAATAGC ACTTTGGAAAATAGTTCTGATACCGTGTCTATTCAGGATAGCAGTGAAGAAGATATGATTGTTCAGAATAGCAATGAAAGCATTTCTGAACAGTTCAGAA CTCGAGAACAAGATGTTGAAGTCTTGGAGCCGTTAAAGTGTGAGTTGGTTTCTGGTGAGTCCACTGGAAACTGTGAGGACAGGCTGCCGGTCAAGGGGAC TGAAGCAAATGGTAAAAAACCAAGTCAGCAGAAGAAATTAGAGGAGAGACCAGTTAATAAATGTAGTGATCAAATAAAGCTAAAAAATACCACTGACAAA AAGAATAATGAAAATCGAGAGTCTGAAAAGAAAGGACAGAGAACAAGTACATTTCAAATAAATGGAAAAGATAATAAACCCAAAATATATTTGAAAGGTG AATGCTTGAAAGAAATTTCTGAGAGTAGAGTAGTAAGTGGTAATGTTGAACCAAAGGTTAATAATATAAATAAAATAATCCCTGAGAATGATATTAAATC ATTGACTGTTAAAGAATCTGCTATAAGGCCATTCATTAATGGTGATGTCATCATGGAAGATTTTAATGAAAGAAACAGCTCCGAAACAAAATCGCATTTG CTGAGTTCTTCAGATGCTGAAGGTAACTACCGAGATAGCCTTGAGACCCTGCCATCAACCAAAGAGTCTGACAGTACACAGACGACCACACCCTCAGCAT CTTGTCCAGAAAGCAATTCAGTTAATCAGGTAGAAGATATGGAAATAGAAACCTCAGAAGTTAAGAAAGTTACTTCATCACCTATTACTTCTGAAGAGGA ATCTAATCTCAGTAATGACTTTATTGATGAAAATGGTCTGCCCATCAACAAAAATGAAAATGTCAATGGAGAATCTAAAAGAAAAACCGTCATCACAGAA GTCACCACGATGACCTCCACAGTGGCCACAGAATCAAAAACTGTGATCAAGGTAGAAAAAGGCGATAAGCAAACTGTGGTTTCTTCCACAGAAAATTGTG CAAAATCCACTGTCACAACCACCACTACAACAGTGACCAAGCTTTCCACACCCTCCACAGGCGGCAGTGTGGACATCATCTCTGTAAAGGAGCAGAGCAA AACCGTGGTCACCACGACAGTGACAGACTCCCTGACCACCACGGGAGGCACACTGGTTACATCTATGACTGTGAGCAAAGAGTATTCCACACGAGACAAA GTGAAACTGATGAAATTTTCAAGACCAAAGAAGACTCGTTCAGGTACAGCTCTGCCATCCTATAGAAAATTTGTTACCAAGAGCAGCAAGAAGAGCATTT TTGTTTTGCCTAATGATGACTTAAAAAAGTTGGCCCGAAAAGGAGGAATCCGAGAGGTCCCTTATTTTAATTACAATGCAAAACCTGCTTTGGATATATG GCCATATCCTTCTCCTAGACCGACCTTTGGCATCACTTGGAGGTATAGACTTCAGACAGTAAAGTCCTTAGCTGGAGTGAGCCTGATGTTACGGTTACTG TGGGCAAGTTTGAGATGGGATGATATGGCGGCCAAGGCTCCTCCAGGAGGAGGGACTACACGGACAGAAACATCCGAAACTGAAATCACAACAACAGAAA TAATTAAGAGGAGAGATGTTGGTCCTTATGGCATTCGATCTGAATATTGTATCAGGAAAATCATTTGTCCCATTGGAGTTCCAGAAACACCAAAAGAAAC GCCTACACCTCAGAGGAAAGGCCTTCGATCAAGTGCACTGCGGCCAAAGAGACCAGAAACGCCCAAGCAAACTGGCCCTGTTATTATTGAAACCTGGGTA GCAGAAGAAGAACTGGAATTGTGGGAGATCAGGGCATTTGCTGAGAGAGTGGAGAAAGAAAAGGCACAAGCAGTTGAGCAACAGGCTAAGAAACGACTGG AGCAGCAGAAGCCGACAGTGATTGCAACTTCCACTACTTCCCCAACAAGCAGTACAACCAGCACCATCTCTCCAGCACAGAAGGTTATGGTGGCCCCCAT AAGTGGCTCAGTTACAACTGGAACCAAAATGGTACTAACTACTAAAGTTGGATCTCCAGCTACAGTAACATTCCAACAAAACAAGAACTTTCATCAAACC TTTGCTACATGGGTTAAGCAAGGCCAGTCAAATTCAGGCGTTGTTCAAGTACAGCAGAAAGTCCTGGGTATCATTCCATCAAGTACAGGTACCAGTCAGC AAACCTTTACTTCATTCCAGCCCAGGACAGCAACAGTCACAATTAGGCCCAATACCTCAGGCTCTGGAGGAACCACAAGCAATTCACAAGTAATCACAGG GCCTCAGATTCGCCCTGGTATGACCGTGATTAGAACACCACTCCAACAGTCAACACTAGGAAAGGCAATTATTCGAACACCTGTGATGGTACAGCCAGGT GCTCCTCAGCAAGTGATGACTCAAATCATCAGGGGGCAGCCTGTCTCCACTGCAGTCTCCGCCCCTAACACGGTTTCCTCAACACCTGGGCAGAAAAGCT TAACTTCAGCAACGTCCACTTCAAATATACAGTCTTCAGCCTCACAACCCCCTCGCCCCCAACAAGGACAAGTGAAGCTCACCATGGCTCAACTTACTCA GTTAACACAGGGCCACGGTGGCAATCAAGGTTTGACAGTAGTAATTCAAGGACAAGGTCAAACTACTGGACAGTTGCAGTTGATACCTCAAGGGGTGACT GTACTCCCAGGCCCAGGCCAGCAGCTAATGCAAGCTGCAATGCCAAATGGTACTGTTCAGCGATTCCTCTTTACCCCATTGGCAACAACAGCCACCACAG CCAGCACCACCACCACCACTGTTTCCACGACAGCAGCAGGTACAGGTGAACAAAGGCAGAGTAAACTGTCACCCCAGATGCAGGTACATCAAGACAAAAC CCTGCCACCAGCTCAGTCATCAAGTGTGGGTCCAGCAGAAGCCCAGCCACAGACTGCTCAGCCTTCAGCTCAGCCCCAGCCCCAAACCCAGCCCCAGTCC CCAGCTCAGCCTGAAGTTCAGACTCAGCCTGAAGTTCAGACCCAAACAACTGTTTCATCCCATGTCCCTTCTGAAGCACAACCCACCCACGCACAGTCAT CCAAGCCCCAAGTTGCAGCACAGTCTCAGCCTCAAAGTAATGTCCAAGGACAGTCTCCTGTTCGTGTCCAAAGTCCATCACAGACTCGAATACGTCCATC AACTCCATCCCAACTGTCTCCTGGACAACAATCCCAGGTTCAGACTACAACCTCACAACCGATTCCAATTCAACCACATACATCTCTTCAGATACCTTCC CAAGGCCAGCCACAGTCACAACCCCAGGTGGTGATGAAGCATAATGCTGTAATAGAACATTTAAAACAGAAAAAGAGCATGACTCCAGCTGAAAGAGAAG AGAATCAAAGAATGATTGTCTGTAACCAGGTGATGAAGTATATTTTGGATAAGATAGATAAAGAAGAAAAACAGGCAGCAAAAAAACGGAAGCGTGAAGA GAGTGTGGAGCAGAAACGTAGCAAGCAGAATGCCACTAAGCTGTCAGCTCTGCTCTTCAAGCACAAAGAGCAGCTCAGAGCCGAGATCCTGAAGAAGAGA GCACTCCTGGACAAGGATCTGCAAATTGAAGTGCAGGAAGAGCTGAAGAGAGACCTGAAAATTAAGAAAGAAAAAGACCTGATGCAGTTGGCTCAGGCCA CAGCAGTAGCTGCACCCTGCCCCCCAGTGACACCAGCTCCTCCAGCCCCTCCAGCCCCTCCACCTTCACCTCCCCCTCCACCTGCTGTGCAACACACAGG CCTTCTGTCCACGCCCACCTTACCTGCTGCTTCCCAGAAGAGGAAGCGGGAAGAGGAAAAAGACTCCAGCTCAAAGTCCAAGAAAAAGAAAATGATCTCT ACTACCTCAAAGGAAACTAAGAAGGACACAAAGCTTTACTGTATCTGTAAAACGCCTTATGATGAATCTAAATTTTATATTGGCTGTGATCGGTGTCAGA ATTGGTACCATGGGCGCTGCGTTGGCATCTTGCAAAGTGAGGCAGAGCTCATTGATGAGTATGTCTGTCCACAGTGCCAGTCAACAGAGGATGCCATGAC AGTGCTCACGCCACTAACAGAGAAGGATTATGAGGGGTTGAAGAGGGTGCTCCGTTCCTTACAGGCCCATAAGATGGCCTGGCCTTTCCTTGAACCAGTA GACCCTAATGATGCACCAGATTATTATGGTGTTATTAAGGAACCTATGGACCTTGCCACCATGGAAGAAAGAGTACAAAGACGATATTATGAAAAGCTGA CGGAATTTGTGGCAGATATGACCAAAATTTTTGATAACTGTCGTTACTACAATCCAAGTGACTCCCCATTTTACCAGTGTGCAGAAGTTCTCGAATCATT CTTTGTACAGAAATTGAAAGGCTTCAAAGCTAGCAGGTCTCATAACAACAAACTGCAGTCTACAGCTTCTTAAAGTTCAGCGTGTTAACCTAACATAAAA CACAGCAAGAATCTGGTTGTCTGAACTATTTTAAATTAAGGAGCCAGATGTTTTTAGTCAGGCTATCCTGACAAGACTTGACCTAAACTTCGTTTTTATT GGTCATAACAGTCCAATTATATTCTTGGCCAATTTTGTCCAACGGACAAGAAAAAAGCAAAGTCAACGACACCATTATCTTGTCAAGATCAGATGGTTTT ACTATTGTGGCAGAAGCGAGAAAACTTTGTTTATTGAAAAAAAAAGAAAAAGAAAGCAAGAAAAAAAGATACTATGGGGTCAAGTGTAACTCCATGGAAA TGCCACGTCTGCTCTTCAGTGAAGAAGCTGGTTTAGAGTCTCACAGAAAACTTTTGACTGTATTTATTTATTGTTGCAAAAAAGACGCTTTTTTATTGCT GCCCTCATTTGTCAGCTAATTATTTTTTCTTATAAAATCCAGCCCCGGTTACATATAATCATCTGTATCTTATCATGATTCCTGTAGGTAAAAGTACAAG ACGACCTCTAGATGTCTTTTCTTTCTATGAAAGGAGCTGCTATGTACACATGTGCACACACACACAACTGGGAATCAACAATGAGTTTATTGTTCATGGT AGATTAAAATTAAGCTTGCATAAAGGTTGGGCTAAGTGGTCCTGGACTACAGACTCTGTTGCCTTGAATATAACAGTACAATTTGTCAATTACTCTGCAC CAGGCTAAAATGAGTAAAATCTATTTGAAGGTATCTTGTTTGTAAACATTTGTCAGATTCTAATTTTTTTCTTTTGTATTAAAATTCAACTATGGATGTA TATGAAACAAAATAAATGGAGATAATTTTTCTCCCACAGACAGAGGTGTCTTTGAATGTGCGCTAATGATTATCTGTAAGCCTTTGTGGGGAGGGAGGCC TGCAAGGTCATGAAAGGCAGAAGAGTCTAATTGTGCCTGGATTTCTCCAGGACAGCAGTGGCCCCTCGTTTTATCATTCCCAGTCCATTGTCATCACGTC AGAGAAAAATCTTCAGGGGTGCTAATCCTGTTGCATCAGTTGATCATACTAACGAGAACGGTAATGCGACAAGATACACATTGCCTTCATCTGTACATTC TGTGATACCAGGCAAATTACCAATTACACACAGCTACTTATATTTTATGAAGGGCATTTTTTAGATGACCTCATCCTCTGTGTTATTTGTTGATTGGGTT TGTTTTCTGTTTGTTGGTTTGTTTGTTTCTTCCACGTAAGGAAAAGTAGTGTAAACAGTAGCGAGAAAATGGAAACCACAGAGGAAGATGTATTTTGCAT GTTTTTCCTTTCAGTGTTCTTACACGTTGTATCACTGCATTGTGGTAATAGCTTCTATAAAATCTGCCATAGTTGGATTATGCAGCTTTGCAAAAATTTT TACTAGATTTTGCACTAACTCATATTAGCTTTGTCCTACCAACTTCTGGAATTTATCTAATTATTGTTTTTCAAAGTTTCTTTCCTTTTAATGTTTCCCT GCTATGCAAAACCTTTCCCAGACCTCAGTTTCTTAAAAGAAAGATGTTGCTACAGTTCCCGATTCTTTCTTATTACAGGCTCAGGTGTACAGGTTATTCT GGGTTAATTTTATCTAATGAAGCCCATTCCTTTTTGTACATAAAGATGTCACTTAAACTTATGCTTACAAACTAAAGACTAATCGCTCAATATGAAAACA TGAAAAAATTTTTGCTTAAAGTATTAAGATGGAAGTAGTTAAATATGGGTTATTTTGTCCTTTTACTTTTTTAAAAAATGTTACATATTGTATGCACTGT GCTGATGCAAGAATTCTACATTTTAATGAGTTATAAAATTATTCTGCATCTCATCACGTCACAGTATTTCTGTACTATTTATTCATATATATAAATATAT ATGGGCTTAATCATTTAAAATTTGTTGCAGCAAGAACTTTCCTACCTGTAGGCAATAGATTGCTATGTTTTTAACAAATTGTGGCAAATTCTAAACAGCA ATTCTTTTGTACGTAATAGGACATTTCATCCTAGAAAAATAAAGTAATGTTTTTGACATTG

refseq_FALZ.F1 (forward primer)
refseq_FALZ.R1 (reverse primer)
Multiple exon skipping

Frame 0

RPPCARPSPFAFLLPPPRLRHEGPAGQAAQAAR GSRCGALRPGPAATAAAAHVRTHRGAPLAAPRQQ PGQVGRRPG*GGAQDAAELAQGGQQ*PEEAAAA AAGPPQHQRPGPGGARRRGRQDGGRGRRRPPGP DHRGPEGRQQSGVR*PRERGGGGRGGHGLRGGGG GGRRRRGDPGF*GRRGG*DGRGRR*LRLSGGDG RRRRRRQLLHGKQLQEP*YLQQHSR*AKTKSTS ASFSYIGRKRHPAP*ISQVL*GFNGA**AYNECH CHLRGTAELWHCFEIISFSL*GLLCSSGEPRAV HTHGRDACCAFESSSA*RRHFQYYLWTC*SER* R*FHTVFHRWDDVARGAAGVL*E**GVPSRSSLP RGRGLPIWTSREQDQSSTVSSRSVSYNKYCSRG IDV*RGDTV**PL*GLSQTWGFALL*DMFSSIP FGMCEATS*GGARGRVAV*SLCSTQGAWCD*LCC *NPKK*TIYST*TYWI**KSEEILVLEPKTHNR RRYRK*K*KENLVLQHKGPTCRIN*LSRQRLLG SRTLQNSRRNA*RNPPTHGHN*RPDQ*GSGQ*QI LSGGS**RNFGIHKSQKGRH**C*KPRRNRKRQ E*D*E*L*RC*EKQRRI*RPVP*KRQ*RQNTR* *P*ARKI*GANRSWG*R*LCVSKSWRQHNKCNFR RD*SL*REEPCGVSLRNPR*QQHGREEGGI*AP PGCARRT*QDM*EQ*H*CYHYLHPA*SGKQ*QQ Q*TKFFPE*IC*GS**S*KWRKRISYTCLYSGRD SR*FQIGEVQRGAK*ISWSWKRSIWLNSNHHQI AESR*QT*SAEEPAGGSRCT*SK*II*GGQRGT GS*LSRRNFTVEHQKGSDHERKYQQLF*IGSRRE VSRLPQSILHQFICFE*APAQRRP**EKASCT* VLSDSSRRVQMERFCPWVQSSYHIYSETDYHPI RKQHPFILSSSQLGIT*GKLDQGSSDV*QTQRIC IGFSHFGVCS*TSCDATNMARIFRTYQVTPDDI N*KRRKGESQKKREETGRRRNDAASDMGKIHIS S*ASGLETKR*RVQSDRIWWLELD**NSCL*VCS *IARQY*CELQKVVRRNQK*YG*KYG*VR*KKM FTKSKKNKNRA*F*KR*GKRFRCCKRSRPK*NG YLKDY*EEGPRCEGALRF*Q**TLQGRTNGSRR* HENRVTCKLSGEFSSRCGQC**GFSSKD*LQKE NKIIQTRWTS*KEN*TVYTGRKTATRKNQVGGW N*GYRKDFYKFFKKSL*ITSNNESKRRVSE*LDE TRTEPKCK**ST*GLDSGMFRK*FLSS*NE*S* SYHKQTLSKRSSVR*CLHSEPRNKMSETKFH*K *HRRKSL*PCQ*RPGTQ*E*NKRK*FFHR*L*TS QCR*YWYFDL*EQKTAHTGGK*HHCFFFQECFT FISA*KYQ*QRCHTSVKSNGL*RKTGM*L*I** HFGK*F*YRVYSG*Q*RRYDCSE*Q*KHF*TVQN SRTRC*SLGAVKV*VGFW*VHWKL*GQAAGQGD *SKW*KTKSAEEIRGETS**M**SNKAKKYH*Q KE**KSRV*KERTENKYISNKWKR**TQNIFER* MLERNF*E*SSKW*C*TKG**YK*NNP*E*Y*I IDC*RICYKAIH*W*CHHGRF**KKQLRNKIAF AEFFRC*R*LPR*P*DPAINQRV*QYTDDHTLSI LSRKQFS*SGRRYGNRNLRS*ESYFITYYF*RG I*SQ**LY**KWSAHQQK*KCQWRI*KKNRHHR SHHDDLHSGHRIKNCDQGRKRR*ANCGFFHRKLC KIHCHNHHYNSDQAFHTLHRRQCGHHLCKGAEQ NRGHHDSDRLPDHHGRHTGYIYDCEQRVFHTRQ SETDEIFKTKEDSFRYSSAIL*KICYQEQQEEHF CFA***LKKVGPKRRNPRGPLF*LQCKTCFGYM AISFS*TDLWHHLEV*TSDSKVLSWSEPDVTVT VGKFEMG*YGGQGSSRRRDYTDRNIRN*NHNNRN N*EERCWSLWHSI*ILYQENHLSHWSSRNTKRN AYTSEERPSIKCTAAKETRNAQANWPCYY*NLG SRRRTGIVGDQGIC*ESGERKGTSS*ATG*ETTG AAEADSDCNFHYFPNKQYNQHHLSSTEGYGGPH KWLSYNWNQNGTNY*SWISSYSNIPTKQELSSN LCYMG*ARPVKFRRCSSTAESPGYHSIKYRYQSA NLYFIPAQDSNSHN*AQYLRLWRNHKQFTSNHR ASDSPWYDRD*NTTPTVNTRKGNYSNTCDGTAR CSSASDDSNHQGAACLHCSLRP*HGFLNTWAEKL NFSNVHFKYTVFSLTTPSPPTRTSEAHHGSTYS VNTGPRWQSRFDSSNSRTRSNYWTVAVDTSRGD CTPRPRPAANASCNAKWYCSAIPLYPIGNNSHHS QHHHHHCFHDSSRYR*TKAE*TVTPDAGTSRQN PATSSVIKCGSSRSPATDCSAFSSAPAPNPAPV PSSA*SSDSA*SSDPNNCFIPCPF*STTHPRTVI QAPSCSTVSASK*CPRTVSCSCPKSITDSNTSI NSIPTVSWTTIPGSDYNLTTDSNSTTYISSDTF PRPATVTTPGGDEA*CCNRTFKTEKEHDSS*KRR ESKNDCL*PGDEVYFG*DR*RRKTGSKKTEA*R ECGAET*QAECH*AVSSALQAQRAAQSRDPEEE STPGQGSAN*SAGRAEERPEN*ERKRPDAVGSGH SSSCTLPPSDTSSSSPSSPSTFTSPSTCCATHR PSVHAHLTCCFPEEEAGRGKRLQLKVQEKENDL YYLKGN*EGHKALLYL*NAL**I*ILYWL*SVSE LVPWALRWHLAK*GRAH**VCLSTVPVNRGCHD SAHATNREGL*GVEEGAPFLTGP*DGLAFP*TS RP**CTRLLWCY*GTYGPCHHGRKSTKTIL*KAD GICGRYDQNF**LSLLQSK*LPILPVCRSSRII LCTEIERLQS*QVS*QQTAVYSFLKFSVLT*HK TQQESGCLNYFKLRSQMFLVRLS*QDLT*TSFLL VITVQLYSWPILSNGQEKSKVNDTIILSRSDGF TIVAEARKLCLLKKKEKESKKKRYYGVKCNSME MPRLLFSEEAGLESHRKLLTVFIYCCKKDAFLLL PSFVS*LFFLIKSSPGYI*SSVSYHDSCR*KYK TTSRCLFFL*KELLCTHVHTHTTGNQQ*VYCSW *IKIKLA*RLG*VVLDYRLCCLEYNSTICQLLCT RLK*VKSI*RYLVCKHLSDSNFFLLY*NSTMDV YETK*MEIIFLPQTEVSLNVR**LSVSLCGEGG LQGHERQKSLIVPGFLQDSSGPSFYHSQSIVITS EKNLQGC*SCCIS*SY*RER*CDKIHIAFICTF CDTRQITNYTQLLIFYEGHFLDDLILCVIC*LG LFSVCWFVCFFHVRKSSVNSSEKMETTEEDVFCM FFLSVFLHVVSLHCGNSFYKICHSWIMQLCKNF Y*ILH*LILALSYQLLEFI*LLFFKVSFLLMFP CYAKPFPDLSFLKERCCYSSRFFLITGSGVQVIL G*FYLMKPIPFCT*RCHLNLCLQTKD*SLNMKT *KNFCLKY*DGSS*IWVILSFYFFKKCYILYAL C*CKNSTF**VIKLFCISSRHSISVLFIHIYKYI WA*SFKICCSKNFPTCRQ*IAMFLTNCGKF*TA ILLYVIGHFILEK*SNVFDI

Frame 1

APPAPAPPPSLSFSPRLGSDMRGRRGRPPKQPA APAAERCAPAPPPPPPPPTSGPIGGLRSRHRGS SRGRWAAAQAEVAPKTRLSSPRGGSSSRRKPPPP PPAPPSTSAPGRGGRGGGGGRTGGGGGGGHLAR TTAARRAVNKVVYDDHESEEEEEEEDMVSEEEE EEDGDAEETQDSEDDEEDEMEEDDDDSDYPEEME DDDDDASYCTESSFRSHSTYSSTPGRRKPRVHR PRSPILEEKDIPPLEFPKSSEDLMVPNEHIMNV IAIYEVLRNFGTVLRLSPFRFEDFCAALVSQEQC TLMAEMHVVLLKAVLREEDTSNTTFGPADLKDS VNSTLYFIDGMTWPEVLRVYCESDKEYHHVLPY QEAEDYPYGPVENKIKVLQFLVDQFLTTNIAREE LMSEGVIQYDDHCRVCHKLGDLLCCETCSAVYH LECVKPPLEEVPEDEWQCEVCVAHKVPGVTDCV AEIQKNKPYIRHEPIGYDRSRRKYWFLNRRLIIE EDTENENEKKIWYYSTKVQLAELIDCLDKDYWE AELCKILEEMREEIHRHMDITEDLTNKARGSNK SFLAAANEEILESIRAKKGDIDNVKSPEETEKDK NETENDSKDAEKNREEFEDQSLEKDSDDKTPDD DPEQGKSEEPTEVGDKGNSVSANLGDNTTNATS EETSPSEGRSPVGCLSETPDSSNMAEKKVASELP QDVPEEPNKTCESSNTSATTTSIQPNLENSNSS SELNSSQSESAKAADDPENGERESHTPVSIQEE IVGDFKSEKSNGELSESPGAGKGASGSTRIITRL RNPDSKLSQLKSQQVAAAAHEANKLFKEGKEVL VVNSQGEISRLSTKKEVIMKGNINNYFKLGQEG KYRVYHNQYSTNSFALNKHQHREDHDKRRHLAHK FCLTPAGEFKWNGSVHGSKVLTISTLRLTITQL ENNIPSSFLHPNWASHRANWIKAVQMCSKPREF ALALAILECAVKPVVMLPIWRESLGHTRLHRMTS IEREEKEKVKKKEKKQEEEETMQQATWVKYTFP VKHQVWKQKGEEYRVTGYGGWSWISKTHVYRFV PKLPGNTNVNYRKSLEGTKNNMDENMDESDKRKC SRSPKKIKIEPDSEKDEVKGSDAAKGADQNEMD ISKITEKKDQDVKELLDSDSDKPCKEEPMEVDD DMKTESHVNCQESSQVDVVNVSEGFHLRTSYKKK TKSSKLDGLLERRIKQFTLEEKQRLEKIKLEGG IKGIGKTSTNSSKNLSESPVITKAKEGCQSDSM RQEQSPNANNDQPEDLIQGCSESDSSVLRMSDPS HTTNKLYPKDRVLDDVSIRSPETKCPKQNSIEN DIEEKVSDLASRGQEPSKSKTKGNDFFIDDSKL ASADDIGTLICKNKKPLIQEESDTIVSSSKSALH SSVPKSTNDRDATPLSRAMDFEGKLGCDSESNS TLENSSDTVSIQDSSEEDMIVQNSNESISEQFR TREQDVEVLEPLKCELVSGESTGNCEDRLPVKGT EANGKKPSQQKKLEERPVNKCSDQIKLKNTTDK KNNENRESEKKGQRTSTFQINGKDNKPKIYLKG ECLKEISESRVVSGNVEPKVNNINKIIPENDIKS LTVKESAIRPFINGDVIMEDFNERNSSETKSHL LSSSDAEGNYRDSLETLPSTKESDSTQTTTPSA SCPESNSVNQVEDMEIETSEVKKVTSSPITSEEE SNLSNDFIDENGLPINKNENVNGESKRKTVITE VTTMTSTVATESKTVIKVEKGDKQTVVSSTENC AKSTVTTTTTTVTKLSTPSTGGSVDIISVKEQSK TVVTTTVTDSLTTTGGTLVTSMTVSKEYSTRDK VKLMKFSRPKKTRSGTALPSYRKFVTKSSKKSI FVLPNDDLKKLARKGGIREVPYFNYNAKPALDIW PYPSPRPTFGITWRYRLQTVKSLAGVSLMLRLL WASLRWDDMAAKAPPGGGTTRTETSETEITTTE IIKRRDVGPYGIRSEYCIRKIICPIGVPETPKET PTPQRKGLRSSALRPKRPETPKQTGPVIIETWV AEEELELWEIRAFAERVEKEKAQAVEQQAKKRL EQQKPTVIATSTTSPTSSTTSTISPAQKVMVAPI SGSVTTGTKMVLTTKVGSPATVTFQQNKNFHQT FATWVKQGQSNSGVVQVQQKVLGIIPSSTGTSQ QTFTSFQPRTATVTIRPNTSGSGGTTSNSQVITG PQIRPGMTVIRTPLQQSTLGKAIIRTPVMVQPG APQQVMTQIIRGQPVSTAVSAPNTVSSTPGQKS LTSATSTSNIQSSASQPPRPQQGQVKLTMAQLTQ LTQGHGGNQGLTVVIQGQGQTTGQLQLIPQGVT VLPGPGQQLMQAAMPNGTVQRFLFTPLATTATT ASTTTTTVSTTAAGTGEQRQSKLSPQMQVHQDKT LPPAQSSSVGPAEAQPQTAQPSAQPQPQTQPQS PAQPEVQTQPEVQTQTTVSSHVPSEAQPTHAQS SKPQVAAQSQPQSNVQGQSPVRVQSPSQTRIRPS TPSQLSPGQQSQVQTTTSQPIPIQPHTSLQIPS QGQPQSQPQVVMKHNAVIEHLKQKKSMTPAERE ENQRMIVCNQVMKYILDKIDKEEKQAAKKRKREE SVEQKRSKQNATKLSALLFKHKEQLRAEILKKR ALLDKDLQIEVQEELKRDLKIKKEKDLMQLAQA TAVAAPCPPVTPAPPAPPAPPPSPPPPPAVQHTG LLSTPTLPAASQKRKREEEKDSSSKSKKKKMIS TTSKETKKDTKLYCICKTPYDESKFYIGCDRCQ NWYHGRCVGILQSEAELIDEYVCPQCQSTEDAMT VLTPLTEKDYEGLKRVLRSLQAHKMAWPFLEPV DPNDAPDYYGVIKEPMDLATMEERVQRRYYEKL TEFVADMTKIFDNCRYYNPSDSPFYQCAEVLESF FVQKLKGFKASRSHNNKLQSTAS*SSAC*PNIK HSKNLVV*TILN*GARCF*SGYPDKT*PKLRFY WS*QSNYILGQFCPTDKKKAKSTTPLSCQDQMVL LLWQKRENFVY*KKKKKKARKKDTMGSSVTPWK CHVCSSVKKLV*SLTENF*LYLFIVAKKTLFYC CPHLSANYFFL*NPAPVTYNHLYLIMIPVGKSTR RPLDVFSFYERSCYVHMCTHTQLGINNEFIVHG RLKLSLHKGWAKWSWTTDSVALNITVQFVNYSA PG*NE*NLFEGILFVNICQILIFFFCIKIQLWMY MKQNKWR*FFSHRQRCL*MCANDYL*AFVGREA CKVMKGRRV*LCLDFSRTAVAPRFIIPSPLSSR QRKIFRGANPVASVDHTNENGNATRYTLPSSVHS VIPGKLPITHSYLYFMKGIF*MTSSSVLFVDWV CFLFVGLFVSST*GKVV*TVARKWKPQRKMYFA CFSFQCSYTLYHCIVVIASIKSAIVGLCSFAKIF TRFCTNSY*LCPTNFWNLSNYCFSKFLSF*CFP AMQNLSQTSVS*KKDVATVPDSFLLQAQVYRLF WVNFI**SPFLFVHKDVT*TYAYKLKTNRSI*KH EKIFA*SIKMEVVKYGLFCPFTFLKNVTYCMHC ADARILHFNEL*NYSASHHVTVFLYYLFIYINI YGLNHLKFVAARTFLPVGNRLLCF*QIVANSKQQ FFCT**DISS*KNKVMFLTL

Frame 2

PPLRPPLPLRFPSPPASAPT*GAGGAGRPSSPR LPLRSAAPRPRRHRRRRPRPDPSGGSARGTAAA AGAGGPPPRLRWRPRRG*ARPGGAAVAGGSRRR RRRPPPAPAPRAGGGEEAGAAGRGAGAAAATWPG PPRPGGPSTKWCTMTTRARRRRKRRTWSPRRRR RRTATPRRPRILRTTRRMRWKRTTMTPIIRRRW KTTTTTPVTARKAASGAIVPTAALQVGENQEYIG LVLLYWKKKTSRPLNFPSPLRI*WCLMSI**MS LPFTRYCGTLALF*DYLLFALRTFVQLW*AKSS AHSWQRCMLCF*KQFCVKKTLPILPLDLLI*KIA LIPHCIS*MG*RGQRCCGCTVRVIRSTITFFLT KRQRTTHMDQ*RTRSKFYSF*SISFLQQILLER N*CLKG*YSMMTIVGFVTNLGICFAVRHVQQYTI WNV*SHLLRRCQRTSGSVKSV*HTRCLV*LTVL LKSKKINHIFDMNLLDMIEVGGNTGS*TEDS** KKIQKMKMKRKFGITAQRSNLQN*LTV*TKIIGK QNSAKF*KKCVKKSTDTWT*LKT*PIRLGAVTN PFWRQLMKKFWNP*EPKRETLIMLKAQKKQKKT RMRLRMTLKMLRKTEKNLKTSPLKKTVTTKHQMM TLSKENLRSQQKLGIKVTLCQQILATTQQMQLQ KRLVPLKGGALWGVSQKPPIAATWQRRRWHLSS PRMCQKNLTRHVRAVTLVLPLPPSSLIWKTVTAA VN*ILPRVNLLRQLMILKMEKENLIHLSLFRKR **VISNRRSPTGS*VNLLELEKEHLAQLESSPD CGIQIANLVS*RASRWQPLHMKQINYLRRAKRYW *LTLKEKFHG*APKRK*S*KEISTIILNWVKKG SIASTTINTPPIHLL*ISTSTEKTMIREGILHI SSV*LQQESSNGTVLSMGPKFLPYLL*D*LSPN* KTTSLHPFFIPTGHHIGQIGSRQFRCVANPENL HWL*PFWSVQLNQL*CYQYGENL*DIPGYTG*H QLKEKKRRKSKKKRRNRKKKKRCSKRHG*NTHFQ LSIRFGNKKVKSTE*QDMVVGAGLVKLMFIGLF LNCQAILM*ITESR*KEPKIIWMKIWMSQIKEN VHEVQKK*K*SLILKKMR*KVQMLQKEQTKMKWI SQRLLRRRTKM*RSS*ILTVINPARKNQWK*TM T*KQSHM*IVRRVLK*MWSMLVRVFI*GLVTKR KQNHPN*MDFLKGELNSLHWKKNSDSKKSSWRVE LRV*ERLLQILQKISLNHQ**RKQKKGVRVTR* DKNRAQMQIMINLRT*FRDVQKVIPQFLE*VIL VIPQTNFIQKIEC*MMSPFGAQKQNVRNKIPLKM T*KKKSLTLPVEARNPVRVKQKEMIFSSMTLN* PVQMILVL*SVRTKNRSYRRKVTPLFLLPRVLY IHQCLKVPMTEMPHLCQEQWTLKENWDVTLNLIA LWKIVLIPCLFRIAVKKI*LFRIAMKAFLNSSE LENKMLKSWSR*SVSWFLVSPLETVRTGCRSRG LKQMVKNQVSRRN*RRDQLINVVIK*S*KIPLTK RIMKIESLKRKDREQVHFK*MEKIINPKYI*KV NA*KKFLRVE**VVMLNQRLII*IK*SLRMILN H*LLKNLL*GHSLMVMSSWKILMKETAPKQNRIC *VLQMLKVTTEIALRPCHQPKSLTVHRRPHPQH LVQKAIQLIR*KIWK*KPQKLRKLLHHLLLLKR NLISVMTLLMKMVCPSTKMKMSMENLKEKPSSQK SPR*PPQWPQNQKL*SR*KKAISKLWFLPQKIV QNPLSQPPLQQ*PSFPHPPQAAVWTSSL*RSRA KPWSPRQ*QTP*PPREAHWLHL*L*AKSIPHETK *N**NFQDQRRLVQVQLCHPIENLLPRAARRAF LFCLMMT*KSWPEKEESERSLILITMQNLLWIY GHILLLDRPLASLGGIDFRQ*SP*LE*A*CYGYC GQV*DGMIWRPRLLQEEGLHGQKHPKLKSQQQK *LRGEMLVLMAFDLNIVSGKSFVPLEFQKHQKK RLHLRGKAFDQVHCGQRDQKRPSKLALLLLKPG* QKKNWNCGRSGHLLREWRKKRHKQLSNRLRNDW SSRSRQ*LQLPLLPQQAVQPAPSLQHRRLWWPP *VAQLQLEPKWY*LLKLDLQLQ*HSNKTRTFIKP LLHGLSKASQIQALFKYSRKSWVSFHQVQVPVS KPLLHSSPGQQQSQLGPIPQALEEPQAIHK*SQ GLRFALV*P*LEHHSNSQH*ERQLFEHL*WYSQV LLSK**LKSSGGSLSPLQSPPLTRFPQHLGRKA *LQQRPLQIYSLQPHNPLAPNKDK*SSPWLNLL S*HRATVAIKV*Q**FKDKVKLLDSCS*YLKG*L YSQAQASS*CKLQCQMVLFSDSSLPHWQQQPPQ PAPPPPLFPRQQQVQVNKGRVNCHPRCRYIKTK PCHQLSHQVWVQQKPSHRLLSLQLSPSPKPSPSP QLSLKFRLSLKFRPKQLFHPMSLLKHNPPTHSH PSPKLQHSLSLKVMSKDSLLFVSKVHHRLEYVH QLHPNCLLDNNPRFRLQPHNRFQFNHIHLFRYLP KASHSHNPRW**SIML**NI*NRKRA*LQLKEK RIKE*LSVTR**SIFWIR*IKKKNRQQKNGSVK RVWSRNVASRMPLSCQLCSSSTKSSSEPRS*RRE HSWTRICKLKCRKS*RET*KLRKKKT*CSWLRP QQ*LHPAPQ*HQLLQPLQPLHLHLPLHLLCNTQ AFCPRPPYLLLPRRGSGKRKKTPAQSPRKRK*SL LPQRKLRRTQSFTVSVKRLMMNLNFILAVIGVR IGTMGAALASCKVRQSSLMSMSVHSASQQRMP* QCSRH*QRRIMRG*RGCSVPYRPIRWPGLSLNQ* TLMMHQIIMVLLRNLWTLPPWKKEYKDDIMKS* RNLWQI*PKFLITVVTTIQVTPHFTSVQKFSNH SLYRN*KASKLAGLITTNCSLQLLKVQRVNLT*N TARIWLSELF*IKEPDVFSQAILTRLDLNFVFI GHNSPIIFLANFVQRTRKKQSQRHHYLVKIRWF YYCGRSEKTLFIEKKRKRKQEKKILWGQV*LHGN ATSALQ*RSWFRVSQKTFDCIYLLLQKRRFFIA ALICQLIIFSYKIQPRLHIIICILS*FL*VKVQ DDL*MSFLSMKGAAMYTCAHTHNWESTMSLLFMV D*N*ACIKVGLSGPGLQTLLP*I*QYNLSITLH QAKMSKIYLKVSCL*TFVRF*FFSFVLKFNYGC I*NKINGDNFSPTDRGVFECALMIICKPLWGGRP ARS*KAEESNCAWISPGQQWPLVLSFPVHCHHV REKSSGVLILLHQLIILTRTVMRQDTHCLHLYI L*YQANYQLHTATYIL*RAFFR*PHPLCYLLIGF VFCLLVCLFLPRKEK*CKQ*RENGNHRGRCILH VFPFSVLTRCITALW**LL*NLP*LDYAALQKF LLDFALTHISFVLPTSGIYLIIVFQSFFPFNVSL LCKTFPRPQFLKRKMLLQFPILSYYRLRCTGYS GLILSNEAHSFLYIKMSLKLMLTN*RLIAQYEN MKKFLLKVLRWK*LNMGYFVLLLF*KMLHIVCTV LMQEFYILMSYKIILHLITSQYFCTIYSYI*IY MGLII*NLLQQELSYL*AIDCYVFNKLWQILNS NSFVRNRTFHPRKIK*CF*H