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Sequences

Sequence NM_001040285

CCAGCGGAGGGCGGGCCGCGGGGGGCGGCCGAGCAGACGGCGGCGGGGTCGTGTACAGCGGGACCCCGTGGAAACGGAGGAACTACAACCAGGGAGTCGT GGGTCTGCATGAAGAAATCAGTGATTTTTATGAATACATGTCTCCAAGACCTGAGGAGGAGAAGATGCGGATGGAGGTGGTGAACAGGATCGAGAGTGTA ATTAAGGAGCTCTGGCCCAGCGCTGACGTCCAGATATTTGGAAGTTTTAAAACTGGACTTTATTTACCTACTAGTGACATCGACCTAGTGGTGTTTGGGA AGTGGGAGAACCTACCCCTCTGGACTCTGGAAGAAGCTCTTCGGAAACACAAAGTCGCAGATGAGGATTCGGTGAAAGTTTTAGACAAAGCAACTGTACC TATTATTAAATTAACAGATTCTTTTACTGAAGTGAAAGTTGATATCAGCTTTAATGTACAGAATGGCGTGAGAGCAGCTGACCTCATCAAAGATTTTACC AAGAAATATCCTGTATTGCCATACTTGGTTTTAGTATTGAAACAATTCCTATTGCAGAGGGACCTTAATGAAGTATTTACAGGTGGAATTGGTTCTTATA GTCTCTTTTTAATGGCAGTCAGTTTCCTTCAGTTACATCCCAGGGAAGATGCTTGCATCCCCAATACAAACTATGGTGTTCTCTTAATAGAATTTTTTGA ATTATATGGACGACACTTCAATTATTTAAAGACTGGCATCCGGATAAAGGATGGTGGTTCATATGTGGCCAAAGATGAAGTACAGAAAAATATGCTAGAT GGCTACAGGCCATCAATGCTTTATATCGAAGATCCTTTACAACCAGGTAACGATGTTGGAAGGAGTTCATATGGGGCCATGCAAGTGAAGCAGGCCTTTG ATTATGCCTACGTTGTTTTGAGTCATGCTGTATCACCAATAGCAAAGTACTATCCCAACAATGAAACAGAAAGCATACTAGGTAGAATAATTAGAGTAAC AGATGAAGTTGCCACATATAGAGATTGGATATCAAAGCAGTGGGGCTTGAAGAATAGACCTGAGCCTTCATGCAATGGTCCAGTGTCGTCCTCTTCTGCC ACACAGTCCAGCTCTAGTGATGTAGATTCCGATGCAACACCATGCAAAACCCCGAAACAGCTGCTTTGCCGTCCGTCCACTGGGAACCGAGTAGGGTCGC AAGATGTATCCTTGGAGTCCTCTCAGGCAGTTGGGAAAATGCAAAGCACCCAAACCACTAACACATCCAACAGCACCAACAAATCTCAGCATGGATCAGC AAGGCTCTTTCGTTCTTCCAGCAAAGGCTTCCAAGGTACAACTCAAACAAGCCATGGTTCCTTGATGACAAACAAACAACATCAAGGCAAATCCAATAAT CAGTATTACCATGGCAAAAAGAGGAAACACAAGAGGGACGCGCCCCTCTCAGACCTCTGTAGATAGTCAGCGCTGCGCGGTGGACTGTCTTCTCTGTGCA ATGATCTCATGCTCAGGACAGTTGCGCAGGGACTCCTGGGAGATATTCAGGAGCCTCACACTGTTCAGACGTTGACTTAGCAACTGCGTTTTTTCCCAGC TCGCCACAGAATGGATCATGAAGACTGACAACTGCAAAAAAAACAAAACAAAACAAAAAAAAAAGCAAGCAAAAAAGAGGGAAAAAAAAGGCTGCTTATT TGATAAGTCATATGCTACAACAGGGTCATTTTAAGATTTAAAGCTTGAATGTAAAATAAATATATTTCTCATTGGCTTTATGCAGAGTTATAGGGAATAG TATTCAGTGTTGGTAGGGTGATAGAAACAAAAAACAGTATCAGAGGATGAGGTGGGGAAGGAAAACAAAGGTATCTGATAGGAAGTCCAGATTCCAAAGG GGAAAGTGATCTGTGCATGTTTTTTTTTTAAATATTTTTGCATATATTTACCATTTTATTGTGTGTATATATAGAAGACCATATAGGAGATTGATATTTG TAATAGTGGATTTGTTAATAATACTTTTTACATAACATTACTGTTTAAATTGTAAACAGATTTTTTCTCAGGATTAGTTTGAAAAATAATCTAAATTGTC ATCTTAACATCCATATATAGGGAAGTGATTAGTTCTATTACTCAATTTGTTTTTCTCAGCATTGAAATGACTTAATAGAACCCTTGTGTCCTGCTGCAAA AATTTTTCCTCTCTAAAGAAAAGGTTTATGGTGGCAAATGATGTTTATTTTATTTTGTAAAAAAAAAAAAATGTACTATGTACTTTTGTGTAAACACTGA AAAATCTCTGGTCATCTCCGAGAATTAACTTGCAACTGTTTTCTATAGTGCTGTCGTCTTGGGCAATGGGCAATTACATGACTTTGTGTTTGCTTCCTTT GCAGTCTTTTTTTTTTCCCCCCATTTCTTCCTAATAGGAAAAAAAAAAAAAAAAAGGTCACCCATGTCTGGTCTCATTCCTGTTGCAGTGAAACTTCGAG TTCCACAGACTTTGCATGCTGGCTTCTCTAACCCTGTGTGCTGCGTGTGCCTGTTTCTCATCTCTTATTCTTTTTAAAATTCATGCTTAACTACTGTGGG AGAATAACTGTAAACAGCTTTAATTAAATCATACTTATAAAAAACTATTTTCTTATATTCCACTCTATGCTTTTGGTATTGTTGATCTTTACAAATTAAA TGGTCTTTGATAATGGATCTATTTTGTATTGCCTTATTAAGACCAAATACTTCTTGTCATCCCATTCTTTATCCTCTTCTTTCATGGAATTGTTATCGTT AATTAAAACTTTTTTAAACATTGGCTTGTTTCAATCATACTGTAAATTTTGGTTGTAGTCAGCTTTGAGTGCAATGAGATGTATAATTCTGTTATCATTA CCTGTTGAGTTTGAAACTCAGTTGGGAATATTTAATATAATAGAATGTAAGTGACATTTCTGAAAATGCTTTCTTTCAGGGTGAAAGCTCTTATGTTTAG CATCAATGTGTATGGCTCTGTTAAATGCAGCCATTTCTGAGACGAGATTCTTTTATATATATATACATATAAAGTACTATTGGCTTTTAGGAGTTTCTTT TATATACATTTATGAAATACTGAAGACCAATCAGACCATTAATGGACACTTAGTGTAACTTTTTATAAAGAAAATAATGCTAAAGTAAGACCAAAACTGA TGTCATCACTGAAATTAACAATTTTCAATATGTTCATATTTTAATTCACAATGGAAAAATGTGTTCCAAAACTGGAAACTCATAGTACTCGTGTAAACTG TGGAAGATTTCAAATGTGATGTTATTTTGACAATGTTTTAAATTTTAGAGTCACATTTTATTCTGATCAGAATTTTTATTGAGATGTTGAGCTTTTGTTT TTGAAACTAGTTTGTCATAACATTGTGCATAATCACAGTATTTATTTTCTAGGACAATTGTGAATGTGTAGACTTATGTTTACTGCTAAGGGAACAATTA TTTATAAAATAATATTAAATCCAGTATTAGCTGCCTATTTCAGACACTTAATACTTGCAGAGATCTATGTTACATTTACCACACTGAAGTTTTTTTTGTT GTTTTTTGTTTGTTTTTAAAGAATCACCCTCATTGTTGAAAGTAAATGTACTCTTAGGGTGCGAATATTAGTGTTCCAATAAGCATGTGATTATATTAAG GTGGTGGTAGCGGGAAGATAATTCTGATTCCATTGGGAATCTTAGGTTTTCGTAAATTTATTGGGAAAATAGTTTTTCCTGTACTGCTGAAGTTTCTTTT TGGTAAACAGTATCTTTCTAAAAGAAAAAAGCATGAAGGAGAAATTGAGGTGTGTATACATTTCCTCAAATGACCAGCATTGTATTCGTGAATACTGTGT ATCTTGCAGTGAACAGTGTGGAAGCTGTTCATTTTTCAATCTGAAGTAAAATACTTTCAAGAACTTTTAGTTTGCCTGCTCATTTGTTTTATACATTTCA TCTATTTGACTCCTATCTTATTTCTTTTTTGAGTTTTAATACTTCCTATATTTTGTGAATATATCAGAAATGTGTCATTTATATATTAGAGTCCATTCAT ATCCATGAATCATAACCTTCCTTTGCTAATACTTGTTGAATGGGATTTTACAAATTCTCCCTCACTCTGGTGACATTTCTCAGGCAGTCATGTATGTGTA CCTGGCCATTAGAAATATTAATATTTAAAGACTGTTTTTTAGAGGAGCTGATGGGTTGGTGAGGTGTCAGCACAAAATCTTACTGGTTATGTTTTGATGA TAAAAGTATATCCATTTTTTCCCTCCAGCTTTAAGGTGACTGTGAAGGTGCCTGGTTTTGAATGTCTTTGTTTGGTTTGGAGATGTCGCACTCAGTTTTC AAATCTAGCTTGGATCTGTAGGACCTATGTTTTTTACAAGTAATTGCCCTCCAGTCTTCAACAGTTGATTCTGTTTTATTTTTATCCTGTTTTGAGTGTA CTTTACCTTTACTTGCATTTTGAGCCTCATTAATATTTAGGTTATTTGATTTGGCTCCAGATATTCCTAGATCTGCACAGGGCAAAACATGGGCTATAGG GTGAGCATTTTTAATTGTCTTTTTCTGCTGGAACCTTATATCTCTCCATGTGTTTTCTGCTCCTTCCCTCCCCCATGAAATGGTAAGTGTGACTTGTGTT TGCCTGAACCTGTGGACTAGTGTTTGGGGTTTCTGGAAACACTAGAGGGTCAGAAAAGAGTAATGACCACCGTGACGTGCAGGATTCTCTTGCTGTGACA TGTTCATTGCAAAGCCCTCTCCAGTGACTAGGAGGTGTAGTTATTAAGGTTGATCTGTTAGAAATCACCATTATTAGGTATTAGTGGTAGATGTTGCTGA TACTTTTATTGGTCATGACTACATCTCAGTTTTACTTTAATATTGATCTATAGTTTGATCAGTTCCTTGAATTCTAATATGTTGATTTCTCAGTGTTTCT GTCACTAACCAAGAATGTTTCTAGGCAGTTGGTTGCTTCACAGTCAAAACTAAATGGTAAACTATCAAAAATACATTCCCAATTTTGCTGTGATAAATAT TGAAATGTTAAAATTAATGAACAGAAGAATTTATTCTTACCCATCTATTCTTGTTCTCCTAGTTCATTAAACTTTCAGTTATTGGAAAGGCACATTCTCA AAGTATTTTATGAGCAAAATATTCTATAAATGCGTCTAACAAACCTAATTGAATATAAAAGTTATATTTAGTAGTTACTGTTGATAGTAATTTTCATCAG GGTCATAGTTCATCTAGTAAAATATTTAGAGAATGATGTTAACATTCCAGCATTAAAGTGGGAACAAAGATTTATATATGAAATTCCTTAAAAGAGTTCA TCTTGCCTTGGTTTCTGACCCTCAAGACTCTAGCTACCTGCCATCTTGTCAAAACATTTGTGGGTAGAATAAGTGTTAAAGATCAAATTTTAATATGCTT CTCGATATTTAACATAGCTAAGAAGCCAGATTTTACTGTAGAAGTTATTTACATGATTTGAAAACTTGACCTAACTGGAAGCCTTTTTCTCAGTCATCTT GTTCTAAGCCATCTTGACTTCACACCCTTAGCGACTTTTCTTTTTTTTTTGGTCAAAGATAATGAGCTAAATATATATAGACGTTGAATGTTGACAAAAT TATTAACCAGAAAAATTGCTTATAAAGGCTGCTGATCTATTTGATACCTAGAATTAAATATTTGAGGACAGTTTTTAGTTAATAAACTGCTAATGTTTAT TTTACTGTCTCTCAGGTTTTTGGTTTTTTTAAAAAAAATGTGTTTGGCCTTTACATTTTCTACTTAAGTGTGTACTTTATTGAGTTTAACCTTGTCTGTA GCCTAGTAGCCTGAAAGAAAAGGAGACAGAACCAGAGAGATGGATGTAGTGCATTCCCTTTGGTTATTACACATTTGTGGTAGCTCCTGGATTTACTGAG AGATATTTTAGCTATGTCAATAAGAACAGCTAATGATGTGGAAATCAGGTGTTCTCTTGTGTATTTCAGTGAACATTTTTATTAGTAGTTGCATATCATC TCTAGTTCCACATTTTAACTTAACGTCTTTGTGGCTTCACCACTGAGCTACCTTTCACTACACCAGCTTCTGTGTGGCCTGGTAACATGGAAGGTCTCTC CTAAGGACAGTCTGGACGTATTTTGGGGGAATGTTATTTATCTTAAAGATGCCTAGAAACAAAACGCATATAGTACCAGTGAGAAACTATGAAGTAAACA AGTTGCTCAGGCCGGGCATGGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCCGAAGCGGGAGGATGGCTTGAGGCTGGGAGTTTGAGACCTTCAT CTCTTAAAAAAACAAACAAAAACCTGAATGGTGAGGTGTGGTGGAATTGGGTAGGGGAGGGAAAGGAGGACTTGGAAAAGCATTCTCCAAAGCCAGCAAC TTGGTGAAGTTCAGTACTTGCCTCTTAGAGGTTAGGCCATGCCTTTCAAAGAGAGTGAAATGATGGGTTATCAGCCACATTCTTGGAGTTAATATTTTTC TTCATCTTTCAGTTTGGGTTCTGTGCTATTCATAGTTCTTCCCTAAGACCATTTCATTATTACCTTTTATATTTAGTTGCAATTTATTATAATATGTTGT TTTGTCCCTGAACTTAATCTCCTAATTTTAAGATCCTCTCTGATTTTTGCATATTGAAACTTACAGAAGTCACTTTAAAAAAGTCTTTTGAAAGTCCTAC AATCCTAAAATAAATCACAAGCTTGTTTGTTAGACGTGTCAAGAGTCTCCAGTCTTTACTACTAAAAAGCAGCACTGCCTTAACACACATTGTTATGGGT GAAAAGTGAGGGACGACCAGTGTAGTTTCTGGATATAAAGTGTGAAGGACTGTTGAGTTAAACATTTTTAGTGGAATATACATAGATAACGTGTATTTAG AAACTTTGGTGAAGCCAGTATTTGTTTTTAGTAACCTTTTTATGTATTTCCTTCTTTGATTAGCATTGTCTTCAGTGTTAAGAAATGTGGACTCCTGTGA GGTGCTGGAGGTTTGAATCATCTTGAAAACTTTCCAATCTTGTCTAGTTACCACTGCAGAGACACTAAGGAATTTACCAGAAAAAGATATTTGATACAAG TGATTTAAGAAATCTCAACATTTCCTGAGGCCGTATCACTGGGCAACCAGTGATGAAAACTATGAATGAATTGCACACCTGGAAGATTTTTTAAGCTAAT GACAGTTTCTTCAAAGATGTCAATTATTTGCCTTGGAAATTTTATAAATTGCATTTCTATGCACATCGGCCTCTAGTGCTTACCACTCGGTTTATTATTC ATAATCTGCAATTCAATAAAGGCTTTGTGTTTTCATTTATCTTCAAAA

refseq_PAPD5.F2 (forward primer)
refseq_PAPD5.R2 (reverse primer)
Alternative acceptor

Frame 0

PAEGGPRGAAEQTAAGSCTAGPRGNGGTTTRES WVCMKKSVIFMNTCLQDLRRRRCGWRW*TGSRV* LRSSGPALTSRYLEVLKLDFIYLLVTST*WCLG SGRTYPSGLWKKLFGNTKSQMRIR*KF*TKQLY LLLN*QILLLK*KLISALMYRMA*EQLTSSKILP RNILYCHTWF*Y*NNSYCRGTLMKYLQVELVLI VSF*WQSVSFSYIPGKMLASPIQTMVFS**NFL NYMDDTSII*RLASG*RMVVHMWPKMKYRKIC*M ATGHQCFISKILYNQVTMLEGVHMGPCK*SRPL IMPTLF*VMLYHQ*QSTIPTMKQKAY*VE*LE* QMKLPHIEIGYQSSGA*RIDLSLHAMVQCRPLLP HSPALVM*IPMQHHAKPRNSCFAVRPLGTE*GR KMYPWSPLRQLGKCKAPKPLTHPTAPTNLSMDQ QGSFVLPAKASKVQLKQAMVP**QTNNIKANPII SITMAKRGNTRGTRPSQTSVDSQRCAVDCLLCA MISCSGQLRRDSWEIFRSLTLFRR*LSNCVFSQ LATEWIMKTDNCKKNKTKQKKKQAKKREKKGCLF DKSYATTGSF*DLKLECKINIFLIGFMQSYRE* YSVLVG**KQKTVSEDEVGKENKGI**EVQIPK GKVICACFFFKYFCIYLPFYCVYI*KTI*EIDIC NSGFVNNTFYITLLFKL*TDFFSGLV*KII*IV ILTSIYREVISSITQFVFLSIEMT**NPCVLLQ KFFLSKEKVYGGK*CLFYFVKKKKCTMYFCVNTE KSLVISEN*LATVFYSAVVLGNGQLHDFVFASF AVFFFSPHFFLIGKKKKKRSPMSGLIPVAVKLR VPQTLHAGFSNPVCCVCLFLISYSF*NSCLTTVG E*L*TALIKSYL*KTIFLYSTLCFWYC*SLQIK WSLIMDLFCIALLRPNTSCHPILYPLLSWNCYR *LKLF*TLACFNHTVNFGCSQL*VQ*DV*FCYHY LLSLKLSWEYLI**NVSDISENAFFQGESSYV* HQCVWLC*MQPFLRRDSFIYIYI*STIGF*EFL LYTFMKY*RPIRPLMDT*CNFL*RK*C*SKTKTD VITEINNFQYVHILIHNGKMCSKTGNS*YSCKL WKISNVMLF*QCFKF*SHILF*SEFLLRC*AFV FETSLS*HCA*SQYLFSRTIVNV*TYVYC*GNNY L*NNIKSSISCLFQTLNTCRDLCYIYHTEVFFV VFCLFLKNHPHC*K*MYS*GANISVPISM*LY* GGGSGKIILIPLGILGFRKFIGKIVFPVLLKFLF GKQYLSKRKKHEGEIEVCIHFLK*PALYS*ILC ILQ*TVWKLFIFQSEVKYFQELLVCLLICFIHF IYLTPILFLF*VLILPIFCEYIRNVSFIY*SPFI SMNHNLPLLILVEWDFTNSPSLW*HFSGSHVCV PGH*KY*YLKTVF*RS*WVGEVSAQNLTGYVLM IKVYPFFPSSFKVTVKVPGFECLCLVWRCRTQFS NLAWICRTYVFYK*LPSSLQQLILFYFYPVLSV LYLYLHFEPH*YLGYLIWLQIFLDLHRAKHGL* GEHF*LSFSAGTLYLSMCFLLLPSPMKW*V*LVF A*TCGLVFGVSGNTRGSEKSNDHRDVQDSLAVT CSLQSPLQ*LGGVVIKVDLLEITIIRY*W*MLL ILLLVMTTSQFYFNIDL*FDQFLEF*YVDFSVFL SLTKNVSRQLVASQSKLNGKLSKIHSQFCCDKY *NVKINEQKNLFLPIYSCSPSSLNFQLLERHIL KVFYEQNIL*MRLTNLIEYKSYI**LLLIVIFIR VIVHLVKYLENDVNIPALKWEQRFIYEIP*KSS SCLGF*PSRL*LPAILSKHLWVE*VLKIKF*YA SRYLT*LRSQILL*KLFT*FENLT*LEAFFSVIL F*AILTSHP*RLFFFFWSKIMS*IYIDVEC*QN Y*PEKLLIKAADLFDT*N*IFEDSF*LINC*CL FYCLSGFWFF*KKCVWPLHFLLKCVLY*V*PCL* PSSLKEKETEPERWM*CIPFGYYTFVVAPGFTE RYFSYVNKNS**CGNQVFSCVFQ*TFLLVVAYH L*FHILT*RLCGFTTELPFTTPASVWPGNMEGLS *GQSGRILGECYLS*RCLETKRI*YQ*ETMK*T SCSGRAWWLTPVIPALWEAEAGGWLEAGSLRPS SLKKTNKNLNGEVWWNWVGEGKEDLEKHSPKPAT W*SSVLAS*RLGHAFQRE*NDGLSATFLELIFF FIFQFGFCAIHSSSLRPFHYYLLYLVAIYYNML FCP*T*SPNFKILSDFCILKLTEVTLKKSFESPT ILK*ITSLFVRRVKSLQSLLLKSSTALTHIVMG EK*GTTSVVSGYKV*RTVELNIFSGIYIDNVYL ETLVKPVFVFSNLFMYFLL*LALSSVLRNVDSCE VLEV*IILKTFQSCLVTTAETLRNLPEKDI*YK *FKKSQHFLRPYHWATSDENYE*IAHLEDFLS* *QFLQRCQLFALEIL*IAFLCTSASSAYHSVYYS *SAIQ*RLCVFIYLQ

Frame 1

QRRAGRGGRPSRRRRGRVQRDPVETEELQPGSR GSA*RNQ*FL*IHVSKT*GGEDADGGGEQDREC N*GALAQR*RPDIWKF*NWTLFTY**HRPSGVWE VGEPTPLDSGRSSSETQSRR*GFGESFRQSNCT YY*INRFFY*SES*YQL*CTEWRESS*PHQRFY QEISCIAILGFSIETIPIAEGP**SIYRWNWFL* SLFNGSQFPSVTSQGRCLHPQYKLWCSLNRIF* IIWTTLQLFKDWHPDKGWWFICGQR*STEKYAR WLQAINALYRRSFTTR*RCWKEFIWGHASEAGL* LCLRCFESCCITNSKVLSQQ*NRKHTR*NN*SN R*SCHI*RLDIKAVGLEE*T*AFMQWSSVVLFC HTVQL**CRFRCNTMQNPETAALPSVHWEPSRVA RCILGVLSGSWENAKHPNH*HIQQHQQISAWIS KALSFFQQRLPRYNSNKPWFLDDKQTTSRQIQ* SVLPWQKEETQEGRAPLRPL*IVSAARWTVFSVQ *SHAQDSCAGTPGRYSGASHCSDVDLATAFFPS SPQNGS*RLTTAKKTKQNKKKSKQKRGKKKAAY LISHMLQQGHFKI*SLNVK*IYFSLALCRVIGNS IQCW*GDRNKKQYQRMRWGRKTKVSDRKSRFQR GK*SVHVFFLNIFAYIYHFIVCIYRRPYRRLIF VIVDLLIILFT*HYCLNCKQIFSQD*FEK*SKLS S*HPYIGK*LVLLLNLFFSALK*LNRTLVSCCK NFSSLKKRFMVANDVYFIL*KKKNVLCTFV*TL KNLWSSPRINLQLFSIVLSSWAMGNYMTLCLLPL QSFFFPPISS**EKKKKKGHPCLVSFLLQ*NFE FHRLCMLASLTLCAACACFSSLILFKIHA*LLW ENNCKQL*LNHTYKKLFSYIPLYAFGIVDLYKLN GL**WIYFVLPY*DQILLVIPFFILFFHGIVIV N*NFFKHWLVSIIL*ILVVVSFECNEMYNSVII TC*V*NSVGNI*YNRM*VTFLKMLSFRVKALMFS INVYGSVKCSHF*DEILLYIYTYKVLLAFRSFF YIHL*NTEDQSDH*WTLSVTFYKENNAKVRPKL MSSLKLTIFNMFIF*FTMEKCVPKLETHSTRVNC GRFQM*CYFDNVLNFRVTFYSDQNFY*DVELLF LKLVCHNIVHNHSIYFLGQL*MCRLMFTAKGTI IYKIILNPVLAAYFRHLILAEIYVTFTTLKFFLL FFVCF*RITLIVESKCTLRVRILVFQ*ACDYIK VVVAGR*F*FHWES*VFVNLLGK*FFLYC*SFF LVNSIFLKEKSMKEKLRCVYISSNDQHCIREYCV SCSEQCGSCSFFNLK*NTFKNF*FACSFVLYIS SI*LLSYFFFEF*YFLYFVNISEMCHLYIRVHS YP*IITFLC*YLLNGILQILPHSGDISQAVMYVY LAIRNINI*RLFFRGADGLVRCQHKILLVMF** *KYIHFFPPALR*L*RCLVLNVFVWFGDVALSF QI*LGSVGPMFFTSNCPPVFNS*FCFIFILF*VY FTFTCILSLINI*VI*FGSRYS*ICTGQNMGYR VSIFNCLFLLEPYISPCVFCSFPPP*NGKCDLC LPEPVD*CLGFLETLEGQKRVMTTVTCRILLL*H VHCKALSSD*EV*LLRLIC*KSPLLGISGRCC* YFYWS*LHLSFTLILIYSLISSLNSNMLISQCF CH*PRMFLGSWLLHSQN*MVNYQKYIPNFAVINI EMLKLMNRRIYSYPSILVLLVH*TFSYWKGTFS KYFMSKIFYKCV*QT*LNIKVIFSSYC***FSS GS*FI**NI*RMMLTFQH*SGNKDLYMKFLKRVH LALVSDPQDSSYLPSCQNICG*NKC*RSNFNML LDI*HS*EARFYCRSYLHDLKT*PNWKPFSQSS CSKPS*LHTLSDFSFFFGQR**AKYI*TLNVDKI INQKNCL*RLLIYLIPRIKYLRTVFS**TANVY FTVSQVFGFFKKNVFGLYIFYLSVYFIEFNLVC SLVA*KKRRQNQRDGCSAFPLVITHLW*LLDLLR DILAMSIRTANDVEIRCSLVYFSEHFY**LHII SSSTF*LNVFVASPLSYLSLHQLLCGLVTWKVS PKDSLDVFWGNVIYLKDA*KQNAYSTSEKL*SKQ VAQAGHGGSRL*SQHFGRPKREDGLRLGV*DLH LLKKQTKT*MVRCGGIG*GRERRTWKSILQSQQ LGEVQYLPLRG*AMPFKESEMMGYQPHSWS*YFS SSFSLGSVLFIVLP*DHFIITFYI*LQFIIICC FVPELNLLILRSSLIFAY*NLQKSL*KSLLKVL QS*NKSQACLLDVSRVSSLYY*KAALP*HTLLWV KSEGRPV*FLDIKCEGLLS*TFLVEYT*ITCI* KLW*SQYLFLVTFLCISFFD*HCLQC*EMWTPV RCWRFESS*KLSNLV*LPLQRH*GIYQKKIFDTS DLRNLNIS*GRITGQPVMKTMNELHTWKIF*AN DSFFKDVNYLPWKFYKLHFYAHRPLVLTTRFII HNLQFNKGFVFSFIFK

Frame 2

SGGRAAGGGRADGGGVVYSGTPWKRRNYNQGVV GLHEEISDFYEYMSPRPEEEKMRMEVVNRIESV IKELWPSADVQIFGSFKTGLYLPTSDIDLVVFG KWENLPLWTLEEALRKHKVADEDSVKVLDKATVP IIKLTDSFTEVKVDISFNVQNGVRAADLIKDFT KKYPVLPYLVLVLKQFLLQRDLNEVFTGGIGSY SLFLMAVSFLQLHPREDACIPNTNYGVLLIEFFE LYGRHFNYLKTGIRIKDGGSYVAKDEVQKNMLD GYRPSMLYIEDPLQPGNDVGRSSYGAMQVKQAF DYAYVVLSHAVSPIAKYYPNNETESILGRIIRVT DEVATYRDWISKQWGLKNRPEPSCNGPVSSSSA TQSSSSDVDSDATPCKTPKQLLCRPSTGNRVGS QDVSLESSQAVGKMQSTQTTNTSNSTNKSQHGSA RLFRSSSKGFQGTTQTSHGSLMTNKQHQGKSNN QYYHGKKRKHKRDAPLSDLCR*SALRGGLSSLC NDLMLRTVAQGLLGDIQEPHTVQTLT*QLRFFPA RHRMDHED*QLQKKQNKTKKKASKKEGKKRLLI **VICYNRVILRFKA*M*NKYISHWLYAEL*GI VFSVGRVIETKNSIRG*GGEGKQRYLIGSPDSKG ESDLCMFFF*IFLHIFTILLCVYIEDHIGD*YL **WIC**YFLHNITV*IVNRFFLRISLKNNLNC HLNIHI*GSD*FYYSICFSQH*NDLIEPLCPAAK IFPL*RKGLWWQMMFILFCKKKKMYYVLLCKH* KISGHLRELTCNCFL*CCRLGQWAIT*LCVCFL CSLFFFPPFLPNRKKKKKKVTHVWSHSCCSETSS STDFACWLL*PCVLRVPVSHLLFFLKFMLNYCG RITVNSFN*IILIKNYFLIFHSMLLVLLIFTN* MVFDNGSILYCLIKTKYFLSSHSLSSSFMELLSL IKTFLNIGLFQSYCKFWL*SALSAMRCIILLSL PVEFETQLGIFNIIECK*HF*KCFLSG*KLLCL ASMCMALLNAAISETRFFYIYIHIKYYWLLGVSF IYIYEILKTNQTINGHLV*LFIKKIMLK*DQN* CHH*N*QFSICSYFNSQWKNVFQNWKLIVLV*T VEDFKCDVILTMF*ILESHFILIRIFIEMLSFCF *N*FVITLCIITVFIF*DNCECVDLCLLLREQL FIK*Y*IQY*LPISDT*YLQRSMLHLPH*SFFC CFLFVFKESPSLLKVNVLLGCEY*CSNKHVIILR WW*REDNSDSIGNLRFS*IYWENSFSCTAEVSF W*TVSF*KKKA*RRN*GVYTFPQMTSIVFVNTV YLAVNSVEAVHFSI*SKILSRTFSLPAHLFYTFH LFDSYLISFLSFNTSYIL*IYQKCVIYILESIH IHES*PSFANTC*MGFYKFSLTLVTFLRQSCMC TWPLEILIFKDCFLEELMGW*GVSTKSYWLCFDD KSISIFSLQL*GDCEGAWF*MSLFGLEMSHSVF KSSLDL*DLCFLQVIALQSSTVDSVLFLSCFEC TLPLLAF*ASLIFRLFDLAPDIPRSAQGKTWAIG *AFLIVFFCWNLISLHVFSAPSLPHEMVSVTCV CLNLWTSVWGFWKH*RVRKE**PP*RAGFSCCD MFIAKPSPVTRRCSY*G*SVRNHHY*VLVVDVAD TFIGHDYISVLL*Y*SIV*SVP*ILIC*FLSVS VTNQECF*AVGCFTVKTKW*TIKNTFPILL**I LKC*N**TEEFILTHLFLFS*FIKLSVIGKAHSQ SIL*AKYSINASNKPN*I*KLYLVVTVDSNFHQ GHSSSSKIFRE*C*HSSIKVGTKIYI*NSLKEF ILPWFLTLKTLATCHLVKTFVGRISVKDQILICF SIFNIAKKPDFTVEVIYMI*KLDLTGSLFLSHL VLSHLDFTPLATFLFFLVKDNELNIYRR*MLTK LLTRKIAYKGC*SI*YLELNI*GQFLVNKLLMFI LLSLRFLVFLKKMCLAFTFST*VCTLLSLTLSV A**PERKGDRTREMDVVHSLWLLHICGSSWIY* EIF*LCQ*EQLMMWKSGVLLCISVNIFISSCISS LVPHFNLTSLWLHH*ATFHYTSFCVAW*HGRSL LRTVWTYFGGMLFILKMPRNKTHIVPVRNYEVN KLLRPGMVAHACNPSTLGGRSGRMA*GWEFETFI S*KNKQKPEW*GVVELGRGGKGGLGKAFSKASN LVKFSTCLLEVRPCLSKRVK*WVISHILGVNIF LHLSVWVLCYS*FFPKTISLLPFIFSCNLL*YVV LSLNLIS*F*DPL*FLHIETYRSHFKKVF*KSY NPKINHKLVC*TCQESPVFTTKKQHCLNTHCYG *KVRDDQCSFWI*SVKDC*VKHF*WNIHR*RVFR NFGEASICF**PFYVFPSLISIVFSVKKCGLL* GAGGLNHLENFPILSSYHCRDTKEFTRKRYLIQ VI*EISTFPEAVSLGNQ**KL*MNCTPGRFFKLM TVSSKMSIICLGNFINCISMHIGL*CLPLGLLF IICNSIKALCFHLSSK

Sequence NM_001040284

CCAGCGGAGGGCGGGCCGCGGGGGGCGGCCGAGCAGACGGCGGCGGGGTCGTGTACAGCGGGACCCCGTGGAAACGGAGGAACTACAACCAGGGAGTCGT GGGTCTGCATGAAGAAATCAGTGATTTTTATGAATACATGTCTCCAAGACCTGAGGAGGAGAAGATGCGGATGGAGGTGGTGAACAGGATCGAGAGTGTA ATTAAGGAGCTCTGGCCCAGCGCTGACGTCCAGATATTTGGAAGTTTTAAAACTGGACTTTATTTACCTACTAGTGACATCGACCTAGTGGTGTTTGGGA AGTGGGAGAACCTACCCCTCTGGACTCTGGAAGAAGCTCTTCGGAAACACAAAGTCGCAGATGAGGATTCGGTGAAAGTTTTAGACAAAGCAACTGTACC TATTATTAAATTAACAGATTCTTTTACTGAAGTGAAAGTTGATATCAGCTTTAATGTACAGAATGGCGTGAGAGCAGCTGACCTCATCAAAGATTTTACC AAGAAATATCCTGTATTGCCATACTTGGTTTTAGTATTGAAACAATTCCTATTGCAGAGGGACCTTAATGAAGTATTTACAGGTGGAATTGGTTCTTATA GTCTCTTTTTAATGGCAGTCAGTTTCCTTCAGTTACATCCCAGGGAAGATGCTTGCATCCCCAATACAAACTATGGTGTTCTCTTAATAGAATTTTTTGA ATTATATGGACGACACTTCAATTATTTAAAGACTGGCATCCGGATAAAGGATGGTGGTTCATATGTGGCCAAAGATGAAGTACAGAAAAATATGCTAGAT GGCTACAGGCCATCAATGCTTTATATCGAAGATCCTTTACAACCAGGTAACGATGTTGGAAGGAGTTCATATGGGGCCATGCAAGTGAAGCAGGCCTTTG ATTATGCCTACGTTGTTTTGAGTCATGCTGTATCACCAATAGCAAAGTACTATCCCAACAATGAAACAGAAAGCATACTAGGTAGAATAATTAGAGTAAC AGATGAAGTTGCCACATATAGAGATTGGATATCAAAGCAGTGGGGCTTGAAGAATAGACCTGAGCCTTCATGCAATGGAAATGGTGTTACCTTGATAGTA GATACTCAGCAGTTAGATAAATGTAATAATAATCTATCTGAAGAAAATGAAGCCCTTGGAAAATGTAGAAGTAAAACCTCGGAATCTCTTAGTAAACACT CTTCAAACTCTTCATCAGGTCCAGTGTCGTCCTCTTCTGCCACACAGTCCAGCTCTAGTGATGTAGATTCCGATGCAACACCATGCAAAACCCCGAAACA GCTGCTTTGCCGTCCGTCCACTGGGAACCGAGTAGGGTCGCAAGATGTATCCTTGGAGTCCTCTCAGGCAGTTGGGAAAATGCAAAGCACCCAAACCACT AACACATCCAACAGCACCAACAAATCTCAGCATGGATCAGCAAGGCTCTTTCGTTCTTCCAGCAAAGGCTTCCAAGGTACAACTCAAACAAGCCATGGTT CCTTGATGACAAACAAACAACATCAAGGCAAATCCAATAATCAGTATTACCATGGCAAAAAGAGGAAACACAAGAGGGACGCGCCCCTCTCAGACCTCTG TAGATAGTCAGCGCTGCGCGGTGGACTGTCTTCTCTGTGCAATGATCTCATGCTCAGGACAGTTGCGCAGGGACTCCTGGGAGATATTCAGGAGCCTCAC ACTGTTCAGACGTTGACTTAGCAACTGCGTTTTTTCCCAGCTCGCCACAGAATGGATCATGAAGACTGACAACTGCAAAAAAAACAAAACAAAACAAAAA AAAAAGCAAGCAAAAAAGAGGGAAAAAAAAGGCTGCTTATTTGATAAGTCATATGCTACAACAGGGTCATTTTAAGATTTAAAGCTTGAATGTAAAATAA ATATATTTCTCATTGGCTTTATGCAGAGTTATAGGGAATAGTATTCAGTGTTGGTAGGGTGATAGAAACAAAAAACAGTATCAGAGGATGAGGTGGGGAA GGAAAACAAAGGTATCTGATAGGAAGTCCAGATTCCAAAGGGGAAAGTGATCTGTGCATGTTTTTTTTTTAAATATTTTTGCATATATTTACCATTTTAT TGTGTGTATATATAGAAGACCATATAGGAGATTGATATTTGTAATAGTGGATTTGTTAATAATACTTTTTACATAACATTACTGTTTAAATTGTAAACAG ATTTTTTCTCAGGATTAGTTTGAAAAATAATCTAAATTGTCATCTTAACATCCATATATAGGGAAGTGATTAGTTCTATTACTCAATTTGTTTTTCTCAG CATTGAAATGACTTAATAGAACCCTTGTGTCCTGCTGCAAAAATTTTTCCTCTCTAAAGAAAAGGTTTATGGTGGCAAATGATGTTTATTTTATTTTGTA AAAAAAAAAAAATGTACTATGTACTTTTGTGTAAACACTGAAAAATCTCTGGTCATCTCCGAGAATTAACTTGCAACTGTTTTCTATAGTGCTGTCGTCT TGGGCAATGGGCAATTACATGACTTTGTGTTTGCTTCCTTTGCAGTCTTTTTTTTTTCCCCCCATTTCTTCCTAATAGGAAAAAAAAAAAAAAAAAGGTC ACCCATGTCTGGTCTCATTCCTGTTGCAGTGAAACTTCGAGTTCCACAGACTTTGCATGCTGGCTTCTCTAACCCTGTGTGCTGCGTGTGCCTGTTTCTC ATCTCTTATTCTTTTTAAAATTCATGCTTAACTACTGTGGGAGAATAACTGTAAACAGCTTTAATTAAATCATACTTATAAAAAACTATTTTCTTATATT CCACTCTATGCTTTTGGTATTGTTGATCTTTACAAATTAAATGGTCTTTGATAATGGATCTATTTTGTATTGCCTTATTAAGACCAAATACTTCTTGTCA TCCCATTCTTTATCCTCTTCTTTCATGGAATTGTTATCGTTAATTAAAACTTTTTTAAACATTGGCTTGTTTCAATCATACTGTAAATTTTGGTTGTAGT CAGCTTTGAGTGCAATGAGATGTATAATTCTGTTATCATTACCTGTTGAGTTTGAAACTCAGTTGGGAATATTTAATATAATAGAATGTAAGTGACATTT CTGAAAATGCTTTCTTTCAGGGTGAAAGCTCTTATGTTTAGCATCAATGTGTATGGCTCTGTTAAATGCAGCCATTTCTGAGACGAGATTCTTTTATATA TATATACATATAAAGTACTATTGGCTTTTAGGAGTTTCTTTTATATACATTTATGAAATACTGAAGACCAATCAGACCATTAATGGACACTTAGTGTAAC TTTTTATAAAGAAAATAATGCTAAAGTAAGACCAAAACTGATGTCATCACTGAAATTAACAATTTTCAATATGTTCATATTTTAATTCACAATGGAAAAA TGTGTTCCAAAACTGGAAACTCATAGTACTCGTGTAAACTGTGGAAGATTTCAAATGTGATGTTATTTTGACAATGTTTTAAATTTTAGAGTCACATTTT ATTCTGATCAGAATTTTTATTGAGATGTTGAGCTTTTGTTTTTGAAACTAGTTTGTCATAACATTGTGCATAATCACAGTATTTATTTTCTAGGACAATT GTGAATGTGTAGACTTATGTTTACTGCTAAGGGAACAATTATTTATAAAATAATATTAAATCCAGTATTAGCTGCCTATTTCAGACACTTAATACTTGCA GAGATCTATGTTACATTTACCACACTGAAGTTTTTTTTGTTGTTTTTTGTTTGTTTTTAAAGAATCACCCTCATTGTTGAAAGTAAATGTACTCTTAGGG TGCGAATATTAGTGTTCCAATAAGCATGTGATTATATTAAGGTGGTGGTAGCGGGAAGATAATTCTGATTCCATTGGGAATCTTAGGTTTTCGTAAATTT ATTGGGAAAATAGTTTTTCCTGTACTGCTGAAGTTTCTTTTTGGTAAACAGTATCTTTCTAAAAGAAAAAAGCATGAAGGAGAAATTGAGGTGTGTATAC ATTTCCTCAAATGACCAGCATTGTATTCGTGAATACTGTGTATCTTGCAGTGAACAGTGTGGAAGCTGTTCATTTTTCAATCTGAAGTAAAATACTTTCA AGAACTTTTAGTTTGCCTGCTCATTTGTTTTATACATTTCATCTATTTGACTCCTATCTTATTTCTTTTTTGAGTTTTAATACTTCCTATATTTTGTGAA TATATCAGAAATGTGTCATTTATATATTAGAGTCCATTCATATCCATGAATCATAACCTTCCTTTGCTAATACTTGTTGAATGGGATTTTACAAATTCTC CCTCACTCTGGTGACATTTCTCAGGCAGTCATGTATGTGTACCTGGCCATTAGAAATATTAATATTTAAAGACTGTTTTTTAGAGGAGCTGATGGGTTGG TGAGGTGTCAGCACAAAATCTTACTGGTTATGTTTTGATGATAAAAGTATATCCATTTTTTCCCTCCAGCTTTAAGGTGACTGTGAAGGTGCCTGGTTTT GAATGTCTTTGTTTGGTTTGGAGATGTCGCACTCAGTTTTCAAATCTAGCTTGGATCTGTAGGACCTATGTTTTTTACAAGTAATTGCCCTCCAGTCTTC AACAGTTGATTCTGTTTTATTTTTATCCTGTTTTGAGTGTACTTTACCTTTACTTGCATTTTGAGCCTCATTAATATTTAGGTTATTTGATTTGGCTCCA GATATTCCTAGATCTGCACAGGGCAAAACATGGGCTATAGGGTGAGCATTTTTAATTGTCTTTTTCTGCTGGAACCTTATATCTCTCCATGTGTTTTCTG CTCCTTCCCTCCCCCATGAAATGGTAAGTGTGACTTGTGTTTGCCTGAACCTGTGGACTAGTGTTTGGGGTTTCTGGAAACACTAGAGGGTCAGAAAAGA GTAATGACCACCGTGACGTGCAGGATTCTCTTGCTGTGACATGTTCATTGCAAAGCCCTCTCCAGTGACTAGGAGGTGTAGTTATTAAGGTTGATCTGTT AGAAATCACCATTATTAGGTATTAGTGGTAGATGTTGCTGATACTTTTATTGGTCATGACTACATCTCAGTTTTACTTTAATATTGATCTATAGTTTGAT CAGTTCCTTGAATTCTAATATGTTGATTTCTCAGTGTTTCTGTCACTAACCAAGAATGTTTCTAGGCAGTTGGTTGCTTCACAGTCAAAACTAAATGGTA AACTATCAAAAATACATTCCCAATTTTGCTGTGATAAATATTGAAATGTTAAAATTAATGAACAGAAGAATTTATTCTTACCCATCTATTCTTGTTCTCC TAGTTCATTAAACTTTCAGTTATTGGAAAGGCACATTCTCAAAGTATTTTATGAGCAAAATATTCTATAAATGCGTCTAACAAACCTAATTGAATATAAA AGTTATATTTAGTAGTTACTGTTGATAGTAATTTTCATCAGGGTCATAGTTCATCTAGTAAAATATTTAGAGAATGATGTTAACATTCCAGCATTAAAGT GGGAACAAAGATTTATATATGAAATTCCTTAAAAGAGTTCATCTTGCCTTGGTTTCTGACCCTCAAGACTCTAGCTACCTGCCATCTTGTCAAAACATTT GTGGGTAGAATAAGTGTTAAAGATCAAATTTTAATATGCTTCTCGATATTTAACATAGCTAAGAAGCCAGATTTTACTGTAGAAGTTATTTACATGATTT GAAAACTTGACCTAACTGGAAGCCTTTTTCTCAGTCATCTTGTTCTAAGCCATCTTGACTTCACACCCTTAGCGACTTTTCTTTTTTTTTTGGTCAAAGA TAATGAGCTAAATATATATAGACGTTGAATGTTGACAAAATTATTAACCAGAAAAATTGCTTATAAAGGCTGCTGATCTATTTGATACCTAGAATTAAAT ATTTGAGGACAGTTTTTAGTTAATAAACTGCTAATGTTTATTTTACTGTCTCTCAGGTTTTTGGTTTTTTTAAAAAAAATGTGTTTGGCCTTTACATTTT CTACTTAAGTGTGTACTTTATTGAGTTTAACCTTGTCTGTAGCCTAGTAGCCTGAAAGAAAAGGAGACAGAACCAGAGAGATGGATGTAGTGCATTCCCT TTGGTTATTACACATTTGTGGTAGCTCCTGGATTTACTGAGAGATATTTTAGCTATGTCAATAAGAACAGCTAATGATGTGGAAATCAGGTGTTCTCTTG TGTATTTCAGTGAACATTTTTATTAGTAGTTGCATATCATCTCTAGTTCCACATTTTAACTTAACGTCTTTGTGGCTTCACCACTGAGCTACCTTTCACT ACACCAGCTTCTGTGTGGCCTGGTAACATGGAAGGTCTCTCCTAAGGACAGTCTGGACGTATTTTGGGGGAATGTTATTTATCTTAAAGATGCCTAGAAA CAAAACGCATATAGTACCAGTGAGAAACTATGAAGTAAACAAGTTGCTCAGGCCGGGCATGGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCCGA AGCGGGAGGATGGCTTGAGGCTGGGAGTTTGAGACCTTCATCTCTTAAAAAAACAAACAAAAACCTGAATGGTGAGGTGTGGTGGAATTGGGTAGGGGAG GGAAAGGAGGACTTGGAAAAGCATTCTCCAAAGCCAGCAACTTGGTGAAGTTCAGTACTTGCCTCTTAGAGGTTAGGCCATGCCTTTCAAAGAGAGTGAA ATGATGGGTTATCAGCCACATTCTTGGAGTTAATATTTTTCTTCATCTTTCAGTTTGGGTTCTGTGCTATTCATAGTTCTTCCCTAAGACCATTTCATTA TTACCTTTTATATTTAGTTGCAATTTATTATAATATGTTGTTTTGTCCCTGAACTTAATCTCCTAATTTTAAGATCCTCTCTGATTTTTGCATATTGAAA CTTACAGAAGTCACTTTAAAAAAGTCTTTTGAAAGTCCTACAATCCTAAAATAAATCACAAGCTTGTTTGTTAGACGTGTCAAGAGTCTCCAGTCTTTAC TACTAAAAAGCAGCACTGCCTTAACACACATTGTTATGGGTGAAAAGTGAGGGACGACCAGTGTAGTTTCTGGATATAAAGTGTGAAGGACTGTTGAGTT AAACATTTTTAGTGGAATATACATAGATAACGTGTATTTAGAAACTTTGGTGAAGCCAGTATTTGTTTTTAGTAACCTTTTTATGTATTTCCTTCTTTGA TTAGCATTGTCTTCAGTGTTAAGAAATGTGGACTCCTGTGAGGTGCTGGAGGTTTGAATCATCTTGAAAACTTTCCAATCTTGTCTAGTTACCACTGCAG AGACACTAAGGAATTTACCAGAAAAAGATATTTGATACAAGTGATTTAAGAAATCTCAACATTTCCTGAGGCCGTATCACTGGGCAACCAGTGATGAAAA CTATGAATGAATTGCACACCTGGAAGATTTTTTAAGCTAATGACAGTTTCTTCAAAGATGTCAATTATTTGCCTTGGAAATTTTATAAATTGCATTTCTA TGCACATCGGCCTCTAGTGCTTACCACTCGGTTTATTATTCATAATCTGCAATTCAATAAAGGCTTTGTGTTTTCATTTATCTTCAAAA

refseq_PAPD5.F2 (forward primer)
refseq_PAPD5.R2 (reverse primer)
Alternative acceptor

Frame 0

PAEGGPRGAAEQTAAGSCTAGPRGNGGTTTRES WVCMKKSVIFMNTCLQDLRRRRCGWRW*TGSRV* LRSSGPALTSRYLEVLKLDFIYLLVTST*WCLG SGRTYPSGLWKKLFGNTKSQMRIR*KF*TKQLY LLLN*QILLLK*KLISALMYRMA*EQLTSSKILP RNILYCHTWF*Y*NNSYCRGTLMKYLQVELVLI VSF*WQSVSFSYIPGKMLASPIQTMVFS**NFL NYMDDTSII*RLASG*RMVVHMWPKMKYRKIC*M ATGHQCFISKILYNQVTMLEGVHMGPCK*SRPL IMPTLF*VMLYHQ*QSTIPTMKQKAY*VE*LE* QMKLPHIEIGYQSSGA*RIDLSLHAMEMVLP*** ILSS*INVIIIYLKKMKPLENVEVKPRNLLVNT LQTLHQVQCRPLLPHSPALVM*IPMQHHAKPRN SCFAVRPLGTE*GRKMYPWSPLRQLGKCKAPKPL THPTAPTNLSMDQQGSFVLPAKASKVQLKQAMV P**QTNNIKANPIISITMAKRGNTRGTRPSQTS VDSQRCAVDCLLCAMISCSGQLRRDSWEIFRSLT LFRR*LSNCVFSQLATEWIMKTDNCKKNKTKQK KKQAKKREKKGCLFDKSYATTGSF*DLKLECKI NIFLIGFMQSYRE*YSVLVG**KQKTVSEDEVGK ENKGI**EVQIPKGKVICACFFFKYFCIYLPFY CVYI*KTI*EIDICNSGFVNNTFYITLLFKL*T DFFSGLV*KII*IVILTSIYREVISSITQFVFLS IEMT**NPCVLLQKFFLSKEKVYGGK*CLFYFV KKKKCTMYFCVNTEKSLVISEN*LATVFYSAVV LGNGQLHDFVFASFAVFFFSPHFFLIGKKKKKRS PMSGLIPVAVKLRVPQTLHAGFSNPVCCVCLFL ISYSF*NSCLTTVGE*L*TALIKSYL*KTIFLY STLCFWYC*SLQIKWSLIMDLFCIALLRPNTSCH PILYPLLSWNCYR*LKLF*TLACFNHTVNFGCS QL*VQ*DV*FCYHYLLSLKLSWEYLI**NVSDI SENAFFQGESSYV*HQCVWLC*MQPFLRRDSFIY IYI*STIGF*EFLLYTFMKY*RPIRPLMDT*CN FL*RK*C*SKTKTDVITEINNFQYVHILIHNGK MCSKTGNS*YSCKLWKISNVMLF*QCFKF*SHIL F*SEFLLRC*AFVFETSLS*HCA*SQYLFSRTI VNV*TYVYC*GNNYL*NNIKSSISCLFQTLNTC RDLCYIYHTEVFFVVFCLFLKNHPHC*K*MYS*G ANISVPISM*LY*GGGSGKIILIPLGILGFRKF IGKIVFPVLLKFLFGKQYLSKRKKHEGEIEVCI HFLK*PALYS*ILCILQ*TVWKLFIFQSEVKYFQ ELLVCLLICFIHFIYLTPILFLF*VLILPIFCE YIRNVSFIY*SPFISMNHNLPLLILVEWDFTNS PSLW*HFSGSHVCVPGH*KY*YLKTVF*RS*WVG EVSAQNLTGYVLMIKVYPFFPSSFKVTVKVPGF ECLCLVWRCRTQFSNLAWICRTYVFYK*LPSSL QQLILFYFYPVLSVLYLYLHFEPH*YLGYLIWLQ IFLDLHRAKHGL*GEHF*LSFSAGTLYLSMCFL LLPSPMKW*V*LVFA*TCGLVFGVSGNTRGSEK SNDHRDVQDSLAVTCSLQSPLQ*LGGVVIKVDLL EITIIRY*W*MLLILLLVMTTSQFYFNIDL*FD QFLEF*YVDFSVFLSLTKNVSRQLVASQSKLNG KLSKIHSQFCCDKY*NVKINEQKNLFLPIYSCSP SSLNFQLLERHILKVFYEQNIL*MRLTNLIEYK SYI**LLLIVIFIRVIVHLVKYLENDVNIPALK WEQRFIYEIP*KSSSCLGF*PSRL*LPAILSKHL WVE*VLKIKF*YASRYLT*LRSQILL*KLFT*F ENLT*LEAFFSVILF*AILTSHP*RLFFFFWSK IMS*IYIDVEC*QNY*PEKLLIKAADLFDT*N*I FEDSF*LINC*CLFYCLSGFWFF*KKCVWPLHF LLKCVLY*V*PCL*PSSLKEKETEPERWM*CIP FGYYTFVVAPGFTERYFSYVNKNS**CGNQVFSC VFQ*TFLLVVAYHL*FHILT*RLCGFTTELPFT TPASVWPGNMEGLS*GQSGRILGECYLS*RCLE TKRI*YQ*ETMK*TSCSGRAWWLTPVIPALWEAE AGGWLEAGSLRPSSLKKTNKNLNGEVWWNWVGE GKEDLEKHSPKPATW*SSVLAS*RLGHAFQRE* NDGLSATFLELIFFFIFQFGFCAIHSSSLRPFHY YLLYLVAIYYNMLFCP*T*SPNFKILSDFCILK LTEVTLKKSFESPTILK*ITSLFVRRVKSLQSL LLKSSTALTHIVMGEK*GTTSVVSGYKV*RTVEL NIFSGIYIDNVYLETLVKPVFVFSNLFMYFLL* LALSSVLRNVDSCEVLEV*IILKTFQSCLVTTA ETLRNLPEKDI*YK*FKKSQHFLRPYHWATSDEN YE*IAHLEDFLS**QFLQRCQLFALEIL*IAFL CTSASSAYHSVYYS*SAIQ*RLCVFIYLQ

Frame 1

QRRAGRGGRPSRRRRGRVQRDPVETEELQPGSR GSA*RNQ*FL*IHVSKT*GGEDADGGGEQDREC N*GALAQR*RPDIWKF*NWTLFTY**HRPSGVWE VGEPTPLDSGRSSSETQSRR*GFGESFRQSNCT YY*INRFFY*SES*YQL*CTEWRESS*PHQRFY QEISCIAILGFSIETIPIAEGP**SIYRWNWFL* SLFNGSQFPSVTSQGRCLHPQYKLWCSLNRIF* IIWTTLQLFKDWHPDKGWWFICGQR*STEKYAR WLQAINALYRRSFTTR*RCWKEFIWGHASEAGL* LCLRCFESCCITNSKVLSQQ*NRKHTR*NN*SN R*SCHI*RLDIKAVGLEE*T*AFMQWKWCYLDS RYSAVR*M***SI*RK*SPWKM*K*NLGIS**TL FKLFIRSSVVLFCHTVQL**CRFRCNTMQNPET AALPSVHWEPSRVARCILGVLSGSWENAKHPNH *HIQQHQQISAWISKALSFFQQRLPRYNSNKPWF LDDKQTTSRQIQ*SVLPWQKEETQEGRAPLRPL *IVSAARWTVFSVQ*SHAQDSCAGTPGRYSGAS HCSDVDLATAFFPSSPQNGS*RLTTAKKTKQNKK KSKQKRGKKKAAYLISHMLQQGHFKI*SLNVK* IYFSLALCRVIGNSIQCW*GDRNKKQYQRMRWG RKTKVSDRKSRFQRGK*SVHVFFLNIFAYIYHFI VCIYRRPYRRLIFVIVDLLIILFT*HYCLNCKQ IFSQD*FEK*SKLSS*HPYIGK*LVLLLNLFFS ALK*LNRTLVSCCKNFSSLKKRFMVANDVYFIL* KKKNVLCTFV*TLKNLWSSPRINLQLFSIVLSS WAMGNYMTLCLLPLQSFFFPPISS**EKKKKKG HPCLVSFLLQ*NFEFHRLCMLASLTLCAACACFS SLILFKIHA*LLWENNCKQL*LNHTYKKLFSYI PLYAFGIVDLYKLNGL**WIYFVLPY*DQILLV IPFFILFFHGIVIVN*NFFKHWLVSIIL*ILVVV SFECNEMYNSVIITC*V*NSVGNI*YNRM*VTF LKMLSFRVKALMFSINVYGSVKCSHF*DEILLY IYTYKVLLAFRSFFYIHL*NTEDQSDH*WTLSVT FYKENNAKVRPKLMSSLKLTIFNMFIF*FTMEK CVPKLETHSTRVNCGRFQM*CYFDNVLNFRVTF YSDQNFY*DVELLFLKLVCHNIVHNHSIYFLGQL *MCRLMFTAKGTIIYKIILNPVLAAYFRHLILA EIYVTFTTLKFFLLFFVCF*RITLIVESKCTLR VRILVFQ*ACDYIKVVVAGR*F*FHWES*VFVNL LGK*FFLYC*SFFLVNSIFLKEKSMKEKLRCVY ISSNDQHCIREYCVSCSEQCGSCSFFNLK*NTF KNF*FACSFVLYISSI*LLSYFFFEF*YFLYFVN ISEMCHLYIRVHSYP*IITFLC*YLLNGILQIL PHSGDISQAVMYVYLAIRNINI*RLFFRGADGL VRCQHKILLVMF***KYIHFFPPALR*L*RCLVL NVFVWFGDVALSFQI*LGSVGPMFFTSNCPPVF NS*FCFIFILF*VYFTFTCILSLINI*VI*FGS RYS*ICTGQNMGYRVSIFNCLFLLEPYISPCVFC SFPPP*NGKCDLCLPEPVD*CLGFLETLEGQKR VMTTVTCRILLL*HVHCKALSSD*EV*LLRLIC *KSPLLGISGRCC*YFYWS*LHLSFTLILIYSLI SSLNSNMLISQCFCH*PRMFLGSWLLHSQN*MV NYQKYIPNFAVINIEMLKLMNRRIYSYPSILVL LVH*TFSYWKGTFSKYFMSKIFYKCV*QT*LNIK VIFSSYC***FSSGS*FI**NI*RMMLTFQH*S GNKDLYMKFLKRVHLALVSDPQDSSYLPSCQNI CG*NKC*RSNFNMLLDI*HS*EARFYCRSYLHDL KT*PNWKPFSQSSCSKPS*LHTLSDFSFFFGQR **AKYI*TLNVDKIINQKNCL*RLLIYLIPRIK YLRTVFS**TANVYFTVSQVFGFFKKNVFGLYIF YLSVYFIEFNLVCSLVA*KKRRQNQRDGCSAFP LVITHLW*LLDLLRDILAMSIRTANDVEIRCSL VYFSEHFY**LHIISSSTF*LNVFVASPLSYLSL HQLLCGLVTWKVSPKDSLDVFWGNVIYLKDA*K QNAYSTSEKL*SKQVAQAGHGGSRL*SQHFGRP KREDGLRLGV*DLHLLKKQTKT*MVRCGGIG*GR ERRTWKSILQSQQLGEVQYLPLRG*AMPFKESE MMGYQPHSWS*YFSSSFSLGSVLFIVLP*DHFI ITFYI*LQFIIICCFVPELNLLILRSSLIFAY*N LQKSL*KSLLKVLQS*NKSQACLLDVSRVSSLY Y*KAALP*HTLLWVKSEGRPV*FLDIKCEGLLS *TFLVEYT*ITCI*KLW*SQYLFLVTFLCISFFD *HCLQC*EMWTPVRCWRFESS*KLSNLV*LPLQ RH*GIYQKKIFDTSDLRNLNIS*GRITGQPVMK TMNELHTWKIF*ANDSFFKDVNYLPWKFYKLHFY AHRPLVLTTRFIIHNLQFNKGFVFSFIFK

Frame 2

SGGRAAGGGRADGGGVVYSGTPWKRRNYNQGVV GLHEEISDFYEYMSPRPEEEKMRMEVVNRIESV IKELWPSADVQIFGSFKTGLYLPTSDIDLVVFG KWENLPLWTLEEALRKHKVADEDSVKVLDKATVP IIKLTDSFTEVKVDISFNVQNGVRAADLIKDFT KKYPVLPYLVLVLKQFLLQRDLNEVFTGGIGSY SLFLMAVSFLQLHPREDACIPNTNYGVLLIEFFE LYGRHFNYLKTGIRIKDGGSYVAKDEVQKNMLD GYRPSMLYIEDPLQPGNDVGRSSYGAMQVKQAF DYAYVVLSHAVSPIAKYYPNNETESILGRIIRVT DEVATYRDWISKQWGLKNRPEPSCNGNGVTLIV DTQQLDKCNNNLSEENEALGKCRSKTSESLSKH SSNSSSGPVSSSSATQSSSSDVDSDATPCKTPKQ LLCRPSTGNRVGSQDVSLESSQAVGKMQSTQTT NTSNSTNKSQHGSARLFRSSSKGFQGTTQTSHG SLMTNKQHQGKSNNQYYHGKKRKHKRDAPLSDLC R*SALRGGLSSLCNDLMLRTVAQGLLGDIQEPH TVQTLT*QLRFFPARHRMDHED*QLQKKQNKTK KKASKKEGKKRLLI**VICYNRVILRFKA*M*NK YISHWLYAEL*GIVFSVGRVIETKNSIRG*GGE GKQRYLIGSPDSKGESDLCMFFF*IFLHIFTIL LCVYIEDHIGD*YL**WIC**YFLHNITV*IVNR FFLRISLKNNLNCHLNIHI*GSD*FYYSICFSQ H*NDLIEPLCPAAKIFPL*RKGLWWQMMFILFC KKKKMYYVLLCKH*KISGHLRELTCNCFL*CCRL GQWAIT*LCVCFLCSLFFFPPFLPNRKKKKKKV THVWSHSCCSETSSSTDFACWLL*PCVLRVPVS HLLFFLKFMLNYCGRITVNSFN*IILIKNYFLIF HSMLLVLLIFTN*MVFDNGSILYCLIKTKYFLS SHSLSSSFMELLSLIKTFLNIGLFQSYCKFWL* SALSAMRCIILLSLPVEFETQLGIFNIIECK*HF *KCFLSG*KLLCLASMCMALLNAAISETRFFYI YIHIKYYWLLGVSFIYIYEILKTNQTINGHLV* LFIKKIMLK*DQN*CHH*N*QFSICSYFNSQWKN VFQNWKLIVLV*TVEDFKCDVILTMF*ILESHF ILIRIFIEMLSFCF*N*FVITLCIITVFIF*DN CECVDLCLLLREQLFIK*Y*IQY*LPISDT*YLQ RSMLHLPH*SFFCCFLFVFKESPSLLKVNVLLG CEY*CSNKHVIILRWW*REDNSDSIGNLRFS*I YWENSFSCTAEVSFW*TVSF*KKKA*RRN*GVYT FPQMTSIVFVNTVYLAVNSVEAVHFSI*SKILS RTFSLPAHLFYTFHLFDSYLISFLSFNTSYIL* IYQKCVIYILESIHIHES*PSFANTC*MGFYKFS LTLVTFLRQSCMCTWPLEILIFKDCFLEELMGW *GVSTKSYWLCFDDKSISIFSLQL*GDCEGAWF *MSLFGLEMSHSVFKSSLDL*DLCFLQVIALQSS TVDSVLFLSCFECTLPLLAF*ASLIFRLFDLAP DIPRSAQGKTWAIG*AFLIVFFCWNLISLHVFS APSLPHEMVSVTCVCLNLWTSVWGFWKH*RVRKE **PP*RAGFSCCDMFIAKPSPVTRRCSY*G*SV RNHHY*VLVVDVADTFIGHDYISVLL*Y*SIV* SVP*ILIC*FLSVSVTNQECF*AVGCFTVKTKW* TIKNTFPILL**ILKC*N**TEEFILTHLFLFS *FIKLSVIGKAHSQSIL*AKYSINASNKPN*I* KLYLVVTVDSNFHQGHSSSSKIFRE*C*HSSIKV GTKIYI*NSLKEFILPWFLTLKTLATCHLVKTF VGRISVKDQILICFSIFNIAKKPDFTVEVIYMI *KLDLTGSLFLSHLVLSHLDFTPLATFLFFLVKD NELNIYRR*MLTKLLTRKIAYKGC*SI*YLELN I*GQFLVNKLLMFILLSLRFLVFLKKMCLAFTF ST*VCTLLSLTLSVA**PERKGDRTREMDVVHSL WLLHICGSSWIY*EIF*LCQ*EQLMMWKSGVLL CISVNIFISSCISSLVPHFNLTSLWLHH*ATFH YTSFCVAW*HGRSLLRTVWTYFGGMLFILKMPRN KTHIVPVRNYEVNKLLRPGMVAHACNPSTLGGR SGRMA*GWEFETFIS*KNKQKPEW*GVVELGRG GKGGLGKAFSKASNLVKFSTCLLEVRPCLSKRVK *WVISHILGVNIFLHLSVWVLCYS*FFPKTISL LPFIFSCNLL*YVVLSLNLIS*F*DPL*FLHIE TYRSHFKKVF*KSYNPKINHKLVC*TCQESPVFT TKKQHCLNTHCYG*KVRDDQCSFWI*SVKDC*V KHF*WNIHR*RVFRNFGEASICF**PFYVFPSL ISIVFSVKKCGLL*GAGGLNHLENFPILSSYHCR DTKEFTRKRYLIQVI*EISTFPEAVSLGNQ**K L*MNCTPGRFFKLMTVSSKMSIICLGNFINCIS MHIGL*CLPLGLLFIICNSIKALCFHLSSK