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Sequences

Sequence NM_198042

AAGCCCCTGAGTAGCTGCTCCGGGAGCTGTGGTGCCCTCTCCTTCTCCCTTTGGCTCCTCTCCTGCTGCCTTACAGTGCCCCCAGAGCCGGCTAGGGGCA
TGGACTTCACCTCCTGGTCCTCTCTTCCTCAGGTATGGCGTTGACGGTGGATGTGGCCGGGCCAGCGCCCTGGGGCTTCCGTATCACAGGGGGCAGGGAT
TTCCACACGCCCATCATGGTGACTAAGGTGGCCGAGCGGGGCAAAGCCAAGGACGCTGACCTCCGGCCTGGAGACATAATCGTGGCCATCAACGGGGAAA
GCGCGGAGGGCATGCTGCATGCCGAGGCCCAGAGCAAGATCCGCCAGAGCCCCTCGCCCCTGCGGCTGCAGCTGGACCGGTCTCAGGCTACGTCTCCAGG
GCAGACCAATGGGGACAGCTCCTTGGAAGTGCTGGCGACTCGCTTCCAGGGCTCCGTGAGGACATACACTGAGAGTCAGTCCTCCTTAAGGTCCTCCTAC
TCCAGCCCAACCTCCCTCAGCCCGAGGGCCGGCAGCCCCTTCTCACCACCACCCTCTAGCAGCTCCCTCACTGGAGAGGCAGCCATCAGCCGCAGCTTCC
AGAGTCTGGCATGTTCCCCGGGCCTCCCCGCTGCTGACCGCCTGTCCTACTCAGGCCGCCCTGGAAGCCGACAGGCCGGCCTCGGCCGCGCTGGCGACTC
GGCGGTGCTGGTGCTGCCGCCTTCCCCGGGCCCTCGTTCCTCCAGGCCCAGCATGGACTCGGAAGGGGGAAGCCTCCTCCTGGACGAGGACTCGGAAGTC
TTCAAGATGCTGCAGGAAAATCGCGAGGGACGGGCGGCCCCCCGACAGTCCAGCTCCTTTCGGCTCTTGCAGGAAGCCCTGGAGGCTGAGGAGAGAGGAA
CCAGGCTGTGCGCAT
CCAGGAGGGCCGGTACCGCCACCCCGGCTGCTACACCTGTGCCGACTGTGGGCTGAACCTGAAGATGCGCGGGCACTTCTGGGTG
GGTGACGAGCTGTACTGTGAGAAGCATGCCCGCCAGCGCTACTCCGCACCTGCCACCCTCAGCTCTCGGGCCTGAGCCCGCCATGCCCTCAGCCTGCCTC
ACTGCTGGGCCAGGGTCATGCCTATATAAGTTGGCATGGCAGGGACAATGGTGGGCAGTTGCTCTTACATGAGCTAAGTTTGGAGACCTGAGGCCCCTTT
GTCCTCGCTGGGTGGGCCAAGGTCTGGGACCTGTCTTGGACTGTGGGAGACTCACCCTCACCTTGCCAGGCCTCTCCCCTGCAGGACTGGCATTGCACTA
GTCTGAGGTGGCCACTGCCTTTGATCAACCTTTGTGTGCGAGGGTCTAAGTAGGGTCGAACACAGAAGTGGGAAGGAGAGGGGTGGGCCAGGGGCTAATG
GTGTCACTGTGTAAAGTTTTTGACATACTAGCTCTATAAATATATGAATATGGACAAAATAAA
  • refseq_PDLIM2.F1 (forward primer)
  • refseq_PDLIM2.R1 (reverse primer)
  • Single exon skipping

Frame 0

KPLSSCSGSCGALSFSLWLLSCCLTVPPEPARG
MDFTSWSSLPQVWR*RWMWPGQRPGASVSQGAGI
STRPSW*LRWPSGAKPRTLTSGLET*SWPSTGK
ARRACCMPRPRARSARAPRPCGCSWTGLRLRLQ
GRPMGTAPWKCWRLASRAP*GHTLRVSPP*GPPT
PAQPPSARGPAAPSHHHPLAAPSLERQPSAAAS
RVWHVPRASPLLTACPTQAALEADRPASAALAT
RRCWCCRLPRALVPPGPAWTRKGEASSWTRTRKS
SRCCRKIARDGRPPDSPAPFGSCRKPWRLRREE
PGCAH
PGGPVPPPRLLHLCRLWAEPEDARALLG
G*RAVL*EACPPALLRTCHPQLSGLSPPCPQPAS
LLGQGHAYISWHGRDNGGQLLLHELSLET*GPF
VLAGWAKVWDLSWTVGDSPSPCQASPLQDWHCT
SLRWPLPLINLCVRGSK*GRTQKWEGEGWARG*W
CHCVKFLTY*LYKYMNMDKI

Frame 1

SP*VAAPGAVVPSPSPFGSSPAALQCPQSRLGA
WTSPPGPLFLRYGVDGGCGRASALGLPYHRGQG
FPHAHHGD*GGRAGQSQGR*PPAWRHNRGHQRGK
RGGHAACRGPEQDPPEPLAPAAAAGPVSGYVSR
ADQWGQLLGSAGDSLPGLREDIH*ESVLLKVLL
LQPNLPQPEGRQPLLTTTL*QLPHWRGSHQPQLP
ESGMFPGPPRC*PPVLLRPPWKPTGRPRPRWRL
GGAGAAAFPGPSFLQAQHGLGRGKPPPGRGLGS
LQDAAGKSRGTGGPPTVQLLSALAGSPGG*GERN
QAVRI
QEGRYRHPGCYTCADCGLNLKMRGHFWV
GDELYCEKHARQRYSAPATLSSRA*ARHALSLP
HCWARVMPI*VGMAGTMVGSCSYMS*VWRPEAPL
SSLGGPRSGTCLGLWETHPHLARPLPCRTGIAL
V*GGHCL*STFVCEGLSRVEHRSGKERGGPGAN
GVTV*SF*HTSSINI*IWTK*

Frame 2

APE*LLRELWCPLLLPLAPLLLPYSAPRAG*GH
GLHLLVLSSSGMALTVDVAGPAPWGFRITGGRD
FHTPIMVTKVAERGKAKDADLRPGDIIVAINGE
SAEGMLHAEAQSKIRQSPSPLRLQLDRSQATSPG
QTNGDSSLEVLATRFQGSVRTYTESQSSLRSSY
SSPTSLSPRAGSPFSPPPSSSSLTGEAAISRSF
QSLACSPGLPAADRLSYSGRPGSRQAGLGRAGDS
AVLVLPPSPGPRSSRPSMDSEGGSLLLDEDSEV
FKMLQENREGRAAPRQSSSFRLLQEALEAEERG
TRLCA
SRRAGTATPAATPVPTVG*T*RCAGTSGW
VTSCTVRSMPASATPHLPPSALGPEPAMPSACL
TAGPGSCLYKLAWQGQWWAVALT*AKFGDLRPL
CPRWVGQGLGPVLDCGRLTLTLPGLSPAGLALH*
SEVATAFDQPLCARV*VGSNTEVGRRGVGQGLM
VSLCKVFDILAL*IYEYGQNK

Sequence NM_176871

AAGCCCCTGAGTAGCTGCTCCGGGAGCTGTGGTGCCCTCTCCTTCTCCCTTTGGCTCCTCTCCTGCTGCCTTACAGTGCCCCCAGAGCCGGCTAGGGGCA
TGGACTTCACCTCCTGGTCCTCTCTTCCTCAGGTATGGCGTTGACGGTGGATGTGGCCGGGCCAGCGCCCTGGGGCTTCCGTATCACAGGGGGCAGGGAT
TTCCACACGCCCATCATGGTGACTAAGGTGGCCGAGCGGGGCAAAGCCAAGGACGCTGACCTCCGGCCTGGAGACATAATCGTGGCCATCAACGGGGAAA
GCGCGGAGGGCATGCTGCATGCCGAGGCCCAGAGCAAGATCCGCCAGAGCCCCTCGCCCCTGCGGCTGCAGCTGGACCGGTCTCAGGCTACGTCTCCAGG
GCAGACCAATGGGGACAGCTCCTTGGAAGTGCTGGCGACTCGCTTCCAGGGCTCCGTGAGGACATACACTGAGAGTCAGTCCTCCTTAAGGTCCTCCTAC
TCCAGCCCAACCTCCCTCAGCCCGAGGGCCGGCAGCCCCTTCTCACCACCACCCTCTAGCAGCTCCCTCACTGGAGAGGCAGCCATCAGCCGCAGCTTCC
AGAGTCTGGCATGTTCCCCGGGCCTCCCCGCTGCTGACCGCCTGTCCTACTCAGGCCGCCCTGGAAGCCGACAGGCCGGCCTCGGCCGCGCTGGCGACTC
GGCGGTGCTGGTGCTGCCGCCTTCCCCGGGCCCTCGTTCCTCCAGGCCCAGCATGGACTCGGAAGGGGGAAGCCTCCTCCTGGACGAGGACTCGGAAGTC
TTCAAGATGCTGCAGGAAAATCGCGAGGGACGGGCGGCCCCCCGACAGTCCAGCTCCTTTCGGCTCTTGCAGGAAGCCCTGGAGGCTGAGGAGAGAGGTG
GCACGCCAGCCTTCTTGCCCAGCTCACTGAGCCCCCAGTCCTCCCTGCCCGCCTCCAGGGCCCTGGCCACCCCTCCCAAGCTCCACACTTGTGAGAAGTG
CAGTACCAGCATCGC
GAACCAGGCTGTGCGCATCCAGGAGGGCCGGTACCGCCACCCCGGCTGCTACACCTGTGCCGACTGTGGGCTGAACCTGAAGATG
CGCGGGCACTTCTGGGAGGACGCTTGTGCTATGGAGGGAATGAGATTGTCACTGGAAGCTTTGGAGGGGATGGTGGAGGGCGCCAAGCGGAGGGACAGGA
GGAAGACCAGGAGACCCATCCAGCCAAGCTGGTGAGACAACCTCTGATCCTGAGGACCGGCCGCCCACCAAGGGTTGGGCCCCCGGGGCCAGGTTGATCT
ACCGACACCTTCCACTTCTTTCCTGGGAGAGACTGCTGGCTTCATTGGTGATTGATTTGGAGGGGGGAAAAAGGGCAGGGTGGCTCAGGCTTTAGGCCCA
GGTACTGGGGAGGCCTGAGGAGCCCTCCTGGAGCTCAGGAGGCCGAGGCTGCCTTAAGCTGTGATCATGCCACTGCATTCCAGCCTGGGAGAGAGAGAGG
ACCTGTCTGTTGAAAAAAACACAAAAACAAATGAATGCATGTGGCCAGTGCCAGGTGAGCTGCCCTGGGGGTTCACTGGAGTTGAGGCAGGGGACAGTAG
TCTCCCCTGCCAGCCTAGGATTTTGGGCGTCATTCACCCACTACCCCTAGTGCTAGTCCCAGAGGATGCTGCGGAGGGGGCAGCCTCAGCTCTCTTTTCA
GAGAAGATCAAAGCTGGGCTTCCCAGGGTGCCTGGCTGGTCCCTGCCGGCAGCTTTGTGCTCTCCGGCTCTTTGTGAAAGGAATCTTGGCGCAGATGTTT
GTGTTGCCTCCTCAGGCACCTGTAGATATAATTTACACCATGATATCATTGTCTCACCTTTTGCCTGGGTGGCTGCCTGAGAAAGGTCTTTCTTTTTATA
GAAAAGATCAAGGCTGTCTGGCGCGGGACTCCATGAGCCCCAGGCGCTGGTCAGAAACGGGGTAGTCTCTTTGGCGCCACCTAGTGTCCAGTTTGGCCCA
TGGCGGGGCCCATTCACGGGGCAACACTGGGCTTCTGGGCACAGCGGGAATACAGAAAGATACAGCACTCCTCATGCCTTCCTGGAGGTAGAAGGCCAGT
GGCAGCGACTGAGCTGGCATGAATGAATAAGAGGATGTGGCACTGAGCGCCAAGGGCTACCTTGGAACGCACCGAGGAGCGTCCCGTGAGTTCAAAGCAG
TGGCCGTGATGCAAAAGGAGGGCTGGGTCTTGGAGACGTGGAGAAGAGGAATGCTGAGTGATGGGGTGGCTGCTGGGGGGATGCTTAGCTCAGAGCAGTG
GCTGATGGGGACACTGAGATAAGATCGGAGGGGAGCTGTCAATGCCAGAAGTGGTTTGAACTTCCCCTTGAGGCTCTAGGGACATTTTGTTTTGAGACAT
GGTCTTGCTCTATTGCCCAGGCTGGAGTGCAGTGGTACAATCTTAGCTCACTGCAGCCTCCACCTCCCAGGCTCAAGAGATCCTCCCACAGCCTCCCAGG
TAGCTGGGACTACAGGCGTGCACCACCACACCCAGCTAATTTTTAAGTTTTTTTTTTTTTTTAAGAGATGGGGTCTCACTATGTTGCCCAGGCTGGTCTC
GAACTTCGGGCCCCAAGCCATCCTCCCACCTTGGCTTTCCAAAGTGTTGGGATTACAAGCGTGAGCTAACCTTGCCCAGCCTCTGGGAACACTTGGAAGG
TTTTAAGCAGAGAAGTGACAGGTTGGAAAAGATGGTTTGGATTATTGATATGGACAGATTCCCACCTGTATGTAGCACGCCATGCTGGGCCAGCAGTGTC
ATAGGAGTGGAGGGGGATAAGTGGGGACTGGGGACATGTGAAATGATGGGCATTCCAGTGAGGCATCGAATGCCTTCTGAGGGCTTTGTAGGTTCCAGCT
CAAATCCCCCTCTGGCTCTTGTTCTTTGGTGTGGCAGCCATCTCTCCTCCCAGGGGTCCTGAGGGTTTCAGCACCAGGGTTCTCTGCAGCCACACAATCA
GCCCGGCTCGGGAGCAAACTCCCCTGGAAGAACGGAGTTATGAGTTGGTCAGCAGAGGAGGCTGGGGACAGGCAGTTTTTGGTCTTTTACCTCTGATCTT
GTCCCCAACCTAAGCCAGCTAGCTGCGTGCTCCCACTCCCTCTGCCGCACGCCGCCCGTCTATGTTCCCGGACTTTGTCCAGTGCAGTGCCCTCTTCCCT
TCCTGCACTGAGGAGATTAACTGAAGTGACAGATTAGAGTTAGAAGTGGCCCAAAGGAGCATCTGGTACAACCCCCTTTGGTTAGAGAAGGGAAAGTGAC
TTTTCCAAAGCTGCACAGCTAGACAGTCATAATGGCTAAGCTCTGGGGGTGCTTTTGATGTGCTAGGGATACTTCCAATGCTTTAACTCACTTAATCCTC
ACAACCCGAGATAGGTACTGTTACCATCCTCTCTGCAGACGAGGAAACCGAGGACCAGGAGGTTCAGTAAATGGTCCAAGTACTCCTAGCTAGTAAGGAA
TGGATCTACAGCCTGCCTCCCAGGTTTCTGGCTTGTGGGGGGCAGAGTTTGTCCCTCTGTCATCAGAGGCAGCCTTCCAGGCACAGCTCTGGTCACCTCT
GGTCACAACTGGAGGTCACCACAGCCCTCCCCAGCGCTCTGTAGGCTCTCAGCTTTGTGCTTCCTCCCACGGGTACTAGCTCCAGCTGAGCTTGCAGGAA
ACCCACTTCCTGAAGCCAGGACTTCCCCATGGGAAGTGCAGGGGCCACTGGGCAGCCTGAGGGCTGACCCTGCTCAGGACACTGTCTGTCTCAGGAACTC
ATGGCAGTGGTTTACCTTGTCAGGAGTGCATGGACGGGCTGCCCCTCCCATTCCTTCAAGCATCACTCAGAGAGCCCTGGCCTGGCTCTAGGCTTGGGAC
TGCGGCTGCCACAGGAAGGGGGCATCCCCCTACTTTGGGTGTTGGGTCAGATCCTGCCCCCGTGCCCGCCAGGGCTCAGGTTCCTCTGAGCTGGTCCTGG
GCCAGGACGCATCTGCATGGCGGTGGTGGGGAGGAGGGGTGCGCCATGGCCTGGAGGGGAGTGTGTGTTGGGGTGTGTGTGTGGAGGTTCTTTTGAGTCA
CACACAAAGCATTGTGCTGAGACACTGCATTCCTGCTGGCTGGGCTTCCTGTTTCCAGATGCATTCCTGTCCCAGAGTCACCACAGAGACTGTTTGGAAT
CCCGCCCCACATTCTCCAAATTCAGGGCGCGATCTGGCAAAGGCTCCCTCCCCCACCCTCTTACTTTGGAGGGAGTCTGGGCTCCCTCCTACCCAGGGAG
GGCTGGCAGGGCTCTGGCACGGCCGGGGTGTGATTCCACACATCTTCTTGGTCTTGCATAAGGCAGTTCCTGGAGACCCAGCACTCTGGTTCTCTCTCTG
CCTGTGAGAAGCGGAATGGGTACTGTCTAGGAGGACTGGGCAGGGTGGGGGCAACCCAGAGGACCCATGGCTAGCAGGGAAGGGCCTGGGCTTGAATGTG
ACTCTGTTGAGACATGGCCAGCAATTCTGGCACTTGGCTGTCATTCGGCTGGCCTGCGCAGAGATTGGCTGTGGGCCTCAGTTTCCCCATTTTATAAAGT
TTTAAAATCTG
  • refseq_PDLIM2.F1 (forward primer)
  • refseq_PDLIM2.R1 (reverse primer)
  • Single exon skipping

Frame 0

KPLSSCSGSCGALSFSLWLLSCCLTVPPEPARG
MDFTSWSSLPQVWR*RWMWPGQRPGASVSQGAGI
STRPSW*LRWPSGAKPRTLTSGLET*SWPSTGK
ARRACCMPRPRARSARAPRPCGCSWTGLRLRLQ
GRPMGTAPWKCWRLASRAP*GHTLRVSPP*GPPT
PAQPPSARGPAAPSHHHPLAAPSLERQPSAAAS
RVWHVPRASPLLTACPTQAALEADRPASAALAT
RRCWCCRLPRALVPPGPAWTRKGEASSWTRTRKS
SRCCRKIARDGRPPDSPAPFGSCRKPWRLRREV
ARQPSCPAH*APSPPCPPPGPWPPLPSSTLVRS
AVPAS
RTRLCASRRAGTATPAATPVPTVG*T*RC
AGTSGRTLVLWRE*DCHWKLWRGWWRAPSGGTG
GRPGDPSSQAGETTSDPEDRPPTKGWAPGARLI
YRHLPLLSWERLLASLVIDLEGGKRAGWLRL*AQ
VLGRPEEPSWSSGGRGCLKL*SCHCIPAWERER
TCLLKKTQKQMNACGQCQVSCPGGSLELRQGTV
VSPASLGFWASFTHYP*C*SQRMLRRGQPQLSFQ
RRSKLGFPGCLAGPCRQLCALRLFVKGILAQMF
VLPPQAPVDIIYTMISLSHLLPGWLPEKGLSFY
RKDQGCLARDSMSPRRWSETG*SLWRHLVSSLAH
GGAHSRGNTGLLGTAGIQKDTALLMPSWR*KAS
GSD*AGMNE*EDVALSAKGYLGTHRGASREFKA
VAVMQKEGWVLETWRRGMLSDGVAAGGMLSSEQW
LMGTLR*DRRGAVNARSGLNFPLRL*GHFVLRH
GLALLPRLECSGTILAHCSLHLPGSRDPPTASQ
VAGTTGVHHHTQLIFKFFFFFKRWGLTMLPRLVS
NFGPQAILPPWLSKVLGLQA*ANLAQPLGTLGR
F*AEK*QVGKDGLDY*YGQIPTCM*HAMLGQQC
HRSGGG*VGTGDM*NDGHSSEASNAF*GLCRFQL
KSPSGSCSLVWQPSLLPGVLRVSAPGFSAATQS
ARLGSKLPWKNGVMSWSAEEAGDRQFLVFYL*S
CPQPKPASCVLPLPLPHAARLCSRTLSSAVPSSL
PALRRLTEVTD*S*KWPKGASGTTPFG*RRESD
FSKAAQLDSHNG*ALGVLLMC*GYFQCFNSLNP
HNPR*VLLPSSLQTRKPRTRRFSKWSKYS*LVRN
GSTACLPGFWLVGGRVCPSVIRGSLPGTALVTS
GHNWRSPQPSPALCRLSALCFLPRVLAPAELAG
NPLPEARTSPWEVQGPLGSLRADPAQDTVCLRNS
WQWFTLSGVHGRAAPPIPSSITQRALAWL*AWD
CGCHRKGASPYFGCWVRSCPRARQGSGSSELVL
GQDASAWRWWGGGVRHGLEGSVCWGVCVEVLLSH
TQSIVLRHCIPAGWASCFQMHSCPRVTTETVWN
PAPHSPNSGRDLAKAPSPTLLLWRESGLPPTQG
GLAGLWHGRGVIPHIFLVLHKAVPGDPALWFSLC
L*EAEWVLSRRTGQGGGNPEDPWLAGKGLGLNV
TLLRHGQQFWHLAVIRLACAEIGCGPQFPHFIK
F*NL

Frame 1

SP*VAAPGAVVPSPSPFGSSPAALQCPQSRLGA
WTSPPGPLFLRYGVDGGCGRASALGLPYHRGQG
FPHAHHGD*GGRAGQSQGR*PPAWRHNRGHQRGK
RGGHAACRGPEQDPPEPLAPAAAAGPVSGYVSR
ADQWGQLLGSAGDSLPGLREDIH*ESVLLKVLL
LQPNLPQPEGRQPLLTTTL*QLPHWRGSHQPQLP
ESGMFPGPPRC*PPVLLRPPWKPTGRPRPRWRL
GGAGAAAFPGPSFLQAQHGLGRGKPPPGRGLGS
LQDAAGKSRGTGGPPTVQLLSALAGSPGG*GERW
HASLLAQLTEPPVLPARLQGPGHPSQAPHL*EV
QYQHR
EPGCAHPGGPVPPPRLLHLCRLWAEPED
ARALLGGRLCYGGNEIVTGSFGGDGGGRQAEGQE
EDQETHPAKLVRQPLILRTGRPPRVGPPGPG*S
TDTFHFFPGRDCWLHW*LIWRGEKGQGGSGFRP
RYWGGLRSPPGAQEAEAALSCDHATAFQPGRERG
PVC*KKHKNK*MHVASAR*AALGVHWS*GRGQ*
SPLPA*DFGRHSPTTPSASPRGCCGGGSLSSLF
REDQSWASQGAWLVPAGSFVLSGSL*KESWRRCL
CCLLRHL*I*FTP*YHCLTFCLGGCLRKVFLFI
EKIKAVWRGTP*APGAGQKRGSLFGAT*CPVWP
MAGPIHGATLGFWAQREYRKIQHSSCLPGGRRPV
AATELA*MNKRMWH*APRATLERTEERPVSSKQ
WP*CKRRAGSWRRGEEEC*VMGWLLGGCLAQSS
G*WGH*DKIGGELSMPEVV*TSP*GSRDILF*DM
VLLYCPGWSAVVQS*LTAASTSQAQEILPQPPR
*LGLQACTTTPS*FLSFFFFLRDGVSLCCPGWS
RTSGPKPSSHLGFPKCWDYKRELTLPSLWEHLEG
FKQRSDRLEKMVWIIDMDRFPPVCSTPCWASSV
IGVEGDKWGLGTCEMMGIPVRHRMPSEGFVGSS
SNPPLALVLWCGSHLSSQGS*GFQHQGSLQPHNQ
PGSGANSPGRTEL*VGQQRRLGTGSFWSFTSDL
VPNLSQLAACSHSLCRTPPVYVPGLCPVQCPLP
FLH*GD*LK*QIRVRSGPKEHLVQPPLVREGKVT
FPKLHS*TVIMAKLWGCF*CARDTSNALTHLIL
TTRDRYCYHPLCRRGNRGPGGSVNGPSTPS**G
MDLQPASQVSGLWGAEFVPLSSEAAFQAQLWSPL
VTTGGHHSPPQRSVGSQLCASSHGY*LQLSLQE
THFLKPGLPHGKCRGHWAA*GLTLLRTLSVSGT
HGSGLPCQECMDGLPLPFLQASLREPWPGSRLGT
AAATGRGHPPTLGVGSDPAPVPARAQVPLSWSW
ARTHLHGGGGEEGCAMAWRGVCVGVCVWRFF*V
THKALC*DTAFLLAGLPVSRCIPVPESPQRLFGI
PPHILQIQGAIWQRLPPPPSYFGGSLGSLLPRE
GWQGSGTAGV*FHTSSWSCIRQFLETQHSGSLS
ACEKRNGYCLGGLGRVGATQRTHG*QGRAWA*M*
LC*DMASNSGTWLSFGWPAQRLAVGLSFPIL*S
FKI

Frame 2

APE*LLRELWCPLLLPLAPLLLPYSAPRAG*GH
GLHLLVLSSSGMALTVDVAGPAPWGFRITGGRD
FHTPIMVTKVAERGKAKDADLRPGDIIVAINGE
SAEGMLHAEAQSKIRQSPSPLRLQLDRSQATSPG
QTNGDSSLEVLATRFQGSVRTYTESQSSLRSSY
SSPTSLSPRAGSPFSPPPSSSSLTGEAAISRSF
QSLACSPGLPAADRLSYSGRPGSRQAGLGRAGDS
AVLVLPPSPGPRSSRPSMDSEGGSLLLDEDSEV
FKMLQENREGRAAPRQSSSFRLLQEALEAEERG
GTPAFLPSSLSPQSSLPASRALATPPKLHTCEKC
STSIA
NQAVRIQEGRYRHPGCYTCADCGLNLKM
RGHFWEDACAMEGMRLSLEALEGMVEGAKRRDR
RKTRRPIQPSW*DNL*S*GPAAHQGLGPRGQVDL
PTPSTSFLGETAGFIGD*FGGGKKGRVAQALGP
GTGEA*GALLELRRPRLP*AVIMPLHSSLGERE
DLSVEKNTKTNECMWPVPGELPWGFTGVEAGDSS
LPCQPRILGVIHPLPLVLVPEDAAEGAASALFS
EKIKAGLPRVPGWSLPAALCSPALCERNLGADV
CVASSGTCRYNLHHDIIVSPFAWVAA*ERSFFL*
KRSRLSGAGLHEPQALVRNGVVSLAPPSVQFGP
WRGPFTGQHWASGHSGNTERYSTPHAFLEVEGQ
WQRLSWHE*IRGCGTERQGLPWNAPRSVP*VQSS
GRDAKGGLGLGDVEKRNAE*WGGCWGDA*LRAV
ADGDTEIRSEGSCQCQKWFELPLEALGTFCFET
WSCSIAQAGVQWYNLSSLQPPPPRLKRSSHSLPG
SWDYRRAPPHPANF*VFFFF*EMGSHYVAQAGL
ELRAPSHPPTLAFQSVGITSVS*PCPASGNTWK
VLSREVTGWKRWFGLLIWTDSHLYVARHAGPAVS
*EWRGISGDWGHVK*WAFQ*GIECLLRAL*VPA
QIPLWLLFFGVAAISPPRGPEGFSTRVLCSHTI
SPAREQTPLEERSYELVSRGGWGQAVFGLLPLIL
SPT*AS*LRAPTPSAARRPSMFPDFVQCSALFP
SCTEEIN*SDRLELEVAQRSIWYNPLWLEKGK*
LFQSCTARQS*WLSSGGAFDVLGILPML*LT*SS
QPEIGTVTILSADEETEDQEVQ*MVQVLLASKE
WIYSLPPRFLACGGQSLSLCHQRQPSRHSSGHL
WSQLEVTTALPSAL*ALSFVLPPTGTSSS*ACRK
PTS*SQDFPMGSAGATGQPEG*PCSGHCLSQEL
MAVVYLVRSAWTGCPSHSFKHHSESPGLALGLG
LRLPQEGGIPLLWVLGQILPPCPPGLRFL*AGPG
PGRICMAVVGRRGAPWPGGECVLGCVCGGSFES
HTKHCAETLHSCWLGFLFPDAFLSQSHHRDCLE
SRPTFSKFRARSGKGSLPHPLTLEGVWAPSYPGR
AGRALARPGCDSTHLLGLA*GSSWRPSTLVLSL
PVRSGMGTV*EDWAGWGQPRGPMASREGPGLEC
DSVETWPAILALGCHSAGLRRDWLWASVSPFYKV
LKS

Sequence NM_021630

AGAGTCGGGTAGACGGCAGCGGGAGCGGTGGCGTCTCCCCGCCTTCCCTCCCTCCCGGGCCTGGGCGCCCAGCCGGACAGGTGAGCGGCAGCCAGGTGAG
CGCGCCCACCTGCGCCTCTCCGCGCGGCCCGCCCTCCCCGGCGCCGGGCTCCTCTCCGCGCCCCTGTCGGCGCGGAACCCTGGCCTCGTCCGCGGCCCAG
CTCCCTGGAGCCTCGCATCAGCGGGGGCGCCCCCGCGAGCTGCGCTCTCCCCGGCCGGAGCGCTCCTCCTCCAGCCCCCAGCCCGCAGGGTACTTTGCCC
TCGGAGCGAAGGAGGCTCCAGAACTGGTAGAGCCGGGCCATCGGGCTGGGCACCTCCCCGCGGCGCCCGCAGCGCGGAGTCCACTGACCGGCTCAAAGGT
ATGGCGTTGACGGTGGATGTGGCCGGGCCAGCGCCCTGGGGCTTCCGTATCACAGGGGGCAGGGATTTCCACACGCCCATCATGGTGACTAAGGTGGCCG
AGCGGGGCAAAGCCAAGGACGCTGACCTCCGGCCTGGAGACATAATCGTGGCCATCAACGGGGAAAGCGCGGAGGGCATGCTGCATGCCGAGGCCCAGAG
CAAGATCCGCCAGAGCCCCTCGCCCCTGCGGCTGCAGCTGGACCGGTCTCAGGCTACGTCTCCAGGGCAGACCAATGGGGACAGCTCCTTGGAAGTGCTG
GCGACTCGCTTCCAGGGCTCCGTGAGGACATACACTGAGAGTCAGTCCTCCTTAAGGTCCTCCTACTCCAGCCCAACCTCCCTCAGCCCGAGGGCCGGCA
GCCCCTTCTCACCACCACCCTCTAGCAGCTCCCTCACTGGAGAGGCAGCCATCAGCCGCAGCTTCCAGAGTCTGGCATGTTCCCCGGGCCTCCCCGCTGC
TGACCGCCTGTCCTACTCAGGCCGCCCTGGAAGCCGACAGGCCGGCCTCGGCCGCGCTGGCGACTCGGCGGTGCTGGTGCTGCCGCCTTCCCCGGGCCCT
CGTTCCTCCAGGCCCAGCATGGACTCGGAAGGGGGAAGCCTCCTCCTGGACGAGGACTCGGAAGTCTTCAAGATGCTGCAGGAAAATCGCGAGGGACGGG
CGGCCCCCCGACAGTCCAGCTCCTTTCGGCTCTTGCAGGAAGCCCTGGAGGCTGAGGAGAGAGGTGGCACGCCAGCCTTCTTGCCCAGCTCACTGAGCCC
CCAGTCCTCCCTGCCCGCCTCCAGGGCCCTGGCCACCCCTCCCAAGCTCCACACTTGTGAGAAGTGCAGTACCAGCATCGC
GAACCAGGCTGTGCGCATC
CAGGAGGGCCGGTACCGCCACCCCGGCTGCTACACCTGTGCCGACTGTGGGCTGAACCTGAAGATGCGCGGGCACTTCTGGGTGGGTGACGAGCTGTACT
GTGAGAAGCATGCCCGCCAGCGCTACTCCGCACCTGCCACCCTCAGCTCTCGGGCCTGAGCCCGCCATGCCCTCAGCCTGCCTCACTGCTGGGCCAGGGT
CATGCCTATATAAGTTGGCATGGCAGGGACAATGGTGGGCAGTTGCTCTTACATGAGCTAAGTTTGGAGACCTGAGGCCCCTTTGTCCTCGCTGGGTGGG
CCAAGGTCTGGGACCTGTCTTGGACTGTGGGAGACTCACCCTCACCTTGCCAGGCCTCTCCCCTGCAGGACTGGCATTGCACTAGTCTGAGGTGGCCACT
GCCTTTGATCAACCTTTGTGTGCGAGGGTCTAAGTAGGGTCGAACACAGAAGTGGGAAGGAGAGGGGTGGGCCAGGGGCTAATGGTGTCACTGTGTAAAG
TTTTTGACATACTAGCTCTATAAATATATGAATATGGACAAAATAAA
  • refseq_PDLIM2.F1 (forward primer)
  • refseq_PDLIM2.R1 (reverse primer)
  • Single exon skipping

Frame 0

RVG*TAAGAVASPRLPSLPGLGAQPDR*AAAR*
ARPPAPLRAARPPRRRAPLRAPVGAEPWPRPRPS
SLEPRISGGAPASCALPGRSAPPPAPSPQGTLP
SERRRLQNW*SRAIGLGTSPRRPQRGVH*PAQR
YGVDGGCGRASALGLPYHRGQGFPHAHHGD*GGR
AGQSQGR*PPAWRHNRGHQRGKRGGHAACRGPE
QDPPEPLAPAAAAGPVSGYVSRADQWGQLLGSA
GDSLPGLREDIH*ESVLLKVLLLQPNLPQPEGRQ
PLLTTTL*QLPHWRGSHQPQLPESGMFPGPPRC
*PPVLLRPPWKPTGRPRPRWRLGGAGAAAFPGP
SFLQAQHGLGRGKPPPGRGLGSLQDAAGKSRGTG
GPPTVQLLSALAGSPGG*GERWHASLLAQLTEP
PVLPARLQGPGHPSQAPHL*EVQYQHR
EPGCAH
PGGPVPPPRLLHLCRLWAEPEDARALLGG*RAVL
*EACPPALLRTCHPQLSGLSPPCPQPASLLGQG
HAYISWHGRDNGGQLLLHELSLET*GPFVLAGW
AKVWDLSWTVGDSPSPCQASPLQDWHCTSLRWPL
PLINLCVRGSK*GRTQKWEGEGWARG*WCHCVK
FLTY*LYKYMNMDKI

Frame 1

ESGRRQRERWRLPAFPPSRAWAPSRTGERQPGE
RAHLRLSARPALPGAGLLSAPLSARNPGLVRGP
APWSLASAGAPPRAALSPAGALLLQPPARRVLCP
RSEGGSRTGRAGPSGWAPPRGARSAESTDRLKG
MALTVDVAGPAPWGFRITGGRDFHTPIMVTKVA
ERGKAKDADLRPGDIIVAINGESAEGMLHAEAQS
KIRQSPSPLRLQLDRSQATSPGQTNGDSSLEVL
ATRFQGSVRTYTESQSSLRSSYSSPTSLSPRAG
SPFSPPPSSSSLTGEAAISRSFQSLACSPGLPAA
DRLSYSGRPGSRQAGLGRAGDSAVLVLPPSPGP
RSSRPSMDSEGGSLLLDEDSEVFKMLQENREGR
AAPRQSSSFRLLQEALEAEERGGTPAFLPSSLSP
QSSLPASRALATPPKLHTCEKCSTSIA
NQAVRI
QEGRYRHPGCYTCADCGLNLKMRGHFWVGDELY
CEKHARQRYSAPATLSSRA*ARHALSLPHCWARV
MPI*VGMAGTMVGSCSYMS*VWRPEAPLSSLGG
PRSGTCLGLWETHPHLARPLPCRTGIALV*GGH
CL*STFVCEGLSRVEHRSGKERGGPGANGVTV*S
F*HTSSINI*IWTK*

Frame 2

SRVDGSGSGGVSPPSLPPGPGRPAGQVSGSQVS
APTCASPRGPPSPAPGSSPRPCRRGTLASSAAQ
LPGASHQRGRPRELRSPRPERSSSSPQPAGYFA
LGAKEAPELVEPGHRAGHLPAAPAARSPLTGSKV
WR*RWMWPGQRPGASVSQGAGISTRPSW*LRWP
SGAKPRTLTSGLET*SWPSTGKARRACCMPRPR
ARSARAPRPCGCSWTGLRLRLQGRPMGTAPWKCW
RLASRAP*GHTLRVSPP*GPPTPAQPPSARGPA
APSHHHPLAAPSLERQPSAAASRVWHVPRASPL
LTACPTQAALEADRPASAALATRRCWCCRLPRAL
VPPGPAWTRKGEASSWTRTRKSSRCCRKIARDG
RPPDSPAPFGSCRKPWRLRREVARQPSCPAH*A
PSPPCPPPGPWPPLPSSTLVRSAVPAS
RTRLCAS
RRAGTATPAATPVPTVG*T*RCAGTSGWVTSCT
VRSMPASATPHLPPSALGPEPAMPSACLTAGPG
SCLYKLAWQGQWWAVALT*AKFGDLRPLCPRWVG
QGLGPVLDCGRLTLTLPGLSPAGLALH*SEVAT
AFDQPLCARV*VGSNTEVGRRGVGQGLMVSLCK
VFDILAL*IYEYGQNK

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