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Sequences

Sequence NM_178156

CGTTTAGTACAGAAATCTCATGGGAGAGAGCATCCATGCATTTACAAATTGTTATTGAATTATTTTATTGAATGATGACACCCAAACTGAGCTAGAACAT AATTCTGGCTCTGCTAGTACATCTTCTGTGTGATCTTGGACAAGTCACTCTACTTTCCTTTCAATTTTCTTTTCTCACAGGGAGATAATCATAAAAACGA CTGTAAAGTACAGCACTTCATAGAGTGCTTTTTGTTTAAAGAGCTGACAATAAATACGAGTCTCAAGGTCTAGGAAAGCCTCCCTCACAACCTGAGCTGC TTGAGGACAAGGGATTTTCTTTTGAATCAGCAGTACCTTATTTGTGTATCTGTGATAGAGTTCCTGGTACATAAGAAGGTCTCAATAAATATGTGAATTT ATGAATATTAGGCAGATTGCAACCTTGACAGGCCACTGCCTCTTAAATCTCCTTTCTGTGATCTTTTAATATTTAACATCTAAAAGGCCGCCGCTACTTG CTTTGGGATAAGTATCCCCGGTATGTACTTTAAAATGCCCAAGCCTAGAGAAATGATTCTTGTCTTAAGGGCACCATTTCGCTCTCCCACCGTAAAGCGC CCCAGGCTTGGGATCTGGGTCCCAAGGCTACAGGGAAGAGTTTGGAACGGGAAGCTCATCTTCCGGCCCTCTGATTGGCCGGCTCGCACTCCACTCACGC GGCGCGCAGCTCTGATTGGCCTCGGCGGCACCCCTCGTCCCGCGACTACTTTGTGTGCTGGGGCGGCGCGCTCCGGTCCTCCCGCTCAGCTGGCGGTCTG GGCTGCTCTGGGGCAGCCCTTCGGTCCACTGCTCTGCATCGCGGGCGCCGGGAATTTTCCGAGTCCGAGCGGCATGTAGAGCGCATGAAGTACAGGACAA TAAAGCTTCCTACACATATCACCAGGAGGATCTCTTTGAAAGATTCACTGCAGGACTACCAGAGAGAATAATTTGTCTGAAGCATCATGTGTTGAAACAA CAGAAGTCTATTCACCTGTGCACTAACTAGAAACAGAGTTACAATGTTTTCAATTCTTTGAGCTCCAGGACTCCAGGGAAGTGAGTTGAAAATCTGAAAA TGCGGCCATGGACTGGTTCCTGGCGTTGGATTATGCTCATTCTTTTTGCCTGGGGGACCTTGCTGTTTTATATAGGTGGTCACTTGGTACGAGATAATGA CCATCCTGATCACTCTAGCCGAGAACTGTCCAAGATTCTGGCAAAGCTTGAACGCTTAAAACAACAGAATGAAGACTTGAGGCGAATGGCCGAATCTCTC CGGATACCAGAAGGCCCTATTGATCAGGGGCCAGCTATAGGAAGAGTACGCGTTTTAGAAGAGCAGCTTGTTAAGGCCAAAGAACAGATTGAAAATTACA AGAAACAGACCAGAAATGGTCTGGGGAAGGATCATGAAATCCTGAGGAGGAGGATTGAAAATGGAGCTAAAGAGCTCTGGTTTTTCCTACAGAGTGAATT GAAGAAATTAAAGAACTTAGAAGGAAATGAACTCCAAAGACATGCAGATGAATTTCTTTTGGATTTAGGACATCATGAAAGGTCTATAATGACGGATCTA TACTACCTCAGTCAGACAGATGGAGCAGGTGATTGGCGGGAAAAAGAGGCCAAAGATCTGACAGAACTGGTTCAGCGGAGAATAACATATCTTCAGAATC CCAAGGACTGCAGCAAAGCCAAAAAGCTGGTGTGTAATATCAACAAAGGCTGTGGCTATGGCTGTCAGCTCCATCATGTGGTCTACTGCTTCATGATTGC ATATGGCACCCAGCGAACACTCATCTTGGAATCTCAGAATTGGCGCTATGCTACTGGTGGATGGGAGACTGTATTTAGGCCTGTAAGTGAGACATGCACA GACAGATCTGGCATCTCCACTGGACACTGGTCAGGTGAAGTGAAGGACAAAAATGTTCAAGTGGTCGAGCTTCCCATTGTAGACAGTCTTCATCCCCGTC CTCCATATTTACCCTTGGCTGTACCAGAAGACCTCGCAGATCGACTTGTACGAGTGCATGGTGACCCTGCAGTGTGGTGGGTGTCTCAGTTTGTCAAATA CTTGATCCGCCCACAGCCTTGGCTAGAAAAAGAAATAGAAGAAGCCACCAAGAAGCTTGGCTTCAAACATCCAGTTATTGGAGTCCATGTCAGACGCACA GACAAAGTGGGAACAGAAGCTGCCTTCCATCCCATTGAAGAGTACATGGTGCATGTTGAAGAACATTTTCAGCTTCTTGCACGCAGAATGCAAGTGGACA AAAAAAGAGTGTATTTGGCCACAGATGACCCTTCTTTATTAAAGGAGGCAAAAACAAAGTACCCCAATTATGAATTTATTAGTGATAACTCTATTTCCTG GTCAGCTGGACTGCACAATCGATACACAGAAAATTCACTTCGTGGAGTGATCCTGGATATACATTTTCTCTCTCAGGCAGACTTCCTAGTGTGTACTTTT TCATCCCAGGTCTGTCGAGTTGCTTATGAAATTATGCAAACACTACATCCTGATGCCTCTGCAAACTTCCATTCTTTAGATGACATCTACTATTTTGGGG GCCAGAATGCCCACAATCAAATTGCCATTTATGCTCACCAACCCCGAACTGCAGATGAAATTCCCATGGAACCTGGAGATATCATTGGTGTGGCTGGAAA TCATTGGGATGGCTATTCTAAAGGTGTCAACAGGAAATTGGGAAGGACGGGCCTATATCCCTCCTACAAAGTTCGAGAGAAGATAGAAACGGTCAAGTAC CCCACATATCCTGAGGCTGAGAAATAAAGCTCAGATGGAAGAGATAAACGACCAAACTCAGTTCGACCAAACTCAGTTCAAACCATTTCAGCCAAACTGT AGATGAAGAGGGCTCTGATCTAACAAAATAAGGTTATATGAGTAGATACTCTCAGCACCAAGAGCAGCTGGGAACTGACATAGGCTTCAATTGGTGGAAT TCCTCTTTAACAAGGGCTGCAATGCCCTCATACCCATGCACAGTACAATAATGTACTCACATATAACATGCAAACAGGTTGTTTTCTACTTTGCCCCTTT CAGTATGTCCCCATAAGACAAACACTGCCATATTGTGTAATTTAAGTGACACAGACATTTTGTGTGAGACTTAAAACATGGTGCCTATATCTGAGAGACC TGTGTGAACTATTGAGAAGATCGGAACAGCTCCTTACTCTGAGGAAGTTGATTCTTATTTGATGGTGGTATTGTGACCACTGAATTCACTCCAGTCAACA GATTCAGAATGAGAATGGACGTTTGGTTTTTTTTTGTTTTTGTTTTTGTTTTTTCCTTTATAAGGTTGTCTGTTTTTTTTTTTTTAAATAATTGCATCAG TTCATTGACCTCATCATTAATAAGTGAAGAATACATCAGAAAATAAAATATTCACTCTCCATTAGAAAATTTTGTAAAACAATGCCATGAACAAATTCTT TAGTACTCAATGTTTCTGGACATTCTCTTTGATAACAAAAAATAAATTTTAAAAAGGAATTTTGTAAAGTTTCTAGAATTTTATATCATTGGATGATATG TTGATCAGCCTTATGTGGAAGAACTGTGATAAAAAGAGGAGCTTTTTAGTTTTTCAGCTTA

refseq_FUT8.F3 (forward primer)
refseq_FUT8.R3 (reverse primer)
Single exon skipping

Frame 0

RLVQKSHGREHPCIYKLLLNYFIE**HPN*ART *FWLC*YIFCVILDKSLYFPFNFLFSQGDNHKND CKVQHFIECFLFKELTINTSLKV*ESLPHNLSC LRTRDFLLNQQYLICVSVIEFLVHKKVSINM*I YEY*ADCNLDRPLPLKSPFCDLLIFNI*KAAATC FGISIPGMYFKMPKPREMILVLRAPFRSPTVKR PRLGIWVPRLQGRVWNGKLIFRPSDWPARTPLT RRAALIGLGGTPRPATTLCAGAARSGPPAQLAVW AALGQPFGPLLCIAGAGNFPSPSGM*SA*STGQ *SFLHISPGGSL*KIHCRTTRENNLSEASCVET TEVYSPVH*LETELQCFQFFELQDSREVS*KSEN AAMDWFLALDYAHSFCLGDLAVLYRWSLGTR** PS*SL*PRTVQDSGKA*TLKTTE*RLEANGRIS PDTRRPY*SGASYRKSTRFRRAAC*GQRTD*KLQ ETDQKWSGEGS*NPEEED*KWS*RALVFPTE*I EEIKELRRK*TPKTCR*ISFGFRTS*KVYNDGS ILPQSDRWSR*LAGKRGQRSDRTGSAENNISSES QGLQQSQKAGV*YQQRLWLWLSAPSCGLLLHDC IWHPANTHLGISELALCYWWMGDCI*ACK*DMH RQIWHLHWTLVR*SEGQKCSSGRASHCRQSSSPS SIFTLGCTRRPRRSTCTSAW*PCSVVGVSVCQI LDPPTALARKRNRRSHQEAWLQTSSYWSPCQTH RQSGNRSCLPSH*RVHGAC*RTFSASCTQNASGQ KKSVFGHR*PFFIKGGKNKVPQL*IY***LYFL VSWTAQSIHRKFTSWSDPGYTFSLSGRLPSVYF FIPGLSSCL*NYANTTS*CLCKLPFFR*HLLFWG PECPQSNCHLCSPTPNCR*NSHGTWRYHWCGWK SLGWLF*RCQQEIGKDGPISLLQSSREDRNGQV PHIS*G*EIKLRWKR*TTKLSSTKLSSNHFSQTV DEEGSDLTK*GYMSRYSQHQEQLGTDIGFNWWN SSLTRAAMPSYPCTVQ*CTHI*HANRLFSTLPL SVCPHKTNTAILCNLSDTDILCET*NMVPISERP V*TIEKIGTAPYSEEVDSYLMVVL*PLNSLQST DSE*EWTFGFFLFLFLFFPL*GCLFFFF*IIAS VH*PHH**VKNTSENKIFTLH*KIL*NNAMNKFF STQCFWTFSLITKNKF*KGIL*SF*NFISLDDM LISLMWKNCDKKRSFLVFQL

Frame 1

V*YRNLMGESIHAFTNCY*IILLNDDTQTELEH NSGSASTSSV*SWTSHSTFLSIFFSHREIIIKT TVKYSTS*SAFCLKS*Q*IRVSRSRKASLTT*AA *GQGIFF*ISSTLFVYL**SSWYIRRSQ*ICEF MNIRQIATLTGHCLLNLLSVIF*YLTSKRPPLL ALG*VSPVCTLKCPSLEK*FLS*GHHFALPP*SA PGLGSGSQGYREEFGTGSSSSGPLIGRLALHSR GAQL*LASAAPLVPRLLCVLGRRAPVLPLSWRS GLLWGSPSVHCSASRAPGIFRVRAACRAHEVQDN KASYTYHQEDLFERFTAGLPERIICLKHHVLKQ QKSIHLCTN*KQSYNVFNSLSSRTPGK*VENLK MRPWTGSWRWIMLILFAWGTLLFYIGGHLVRDND HPDHSSRELSKILAKLERLKQQNEDLRRMAESL RIPEGPIDQGPAIGRVRVLEEQLVKAKEQIENY KKQTRNGLGKDHEILRRRIENGAKELWFFLQSEL KKLKNLEGNELQRHADEFLLDLGHHERSIMTDL YYLSQTDGAGDWREKEAKDLTELVQRRITYLQN PKDCSKAKKLVCNINKGCGYGCQLHHVVYCFMIA YGTQRTLILESQNWRYATGGWETVFRPVSETCT DRSGISTGHWSGEVKDKNVQVVELPIVDSLHPR PPYLPLAVPEDLADRLVRVHGDPAVWWVSQFVKY LIRPQPWLEKEIEEATKKLGFKHPVIGVHVRRT DKVGTEAAFHPIEEYMVHVEEHFQLLARRMQVD KKRVYLATDDPSLLKEAKTKYPNYEFISDNSISW SAGLHNRYTENSLRGVILDIHFLSQADFLVCTF SSQVCRVAYEIMQTLHPDASANFHSLDDIYYFG GQNAHNQIAIYAHQPRTADEIPMEPGDIIGVAGN HWDGYSKGVNRKLGRTGLYPSYKVREKIETVKY PTYPEAEK*SSDGRDKRPNSVRPNSVQTISAKL *MKRALI*QNKVI*VDTLSTKSSWELT*ASIGGI PL*QGLQCPHTHAQYNNVLTYNMQTGCFLLCPF QYVPIRQTLPYCVI*VTQTFCVRLKTWCLYLRD LCELLRRSEQLLTLRKLILI*WWYCDH*IHSSQQ IQNENGRLVFFCFCFCFFLYKVVCFFFFK*LHQ FIDLIINK*RIHQKIKYSLSIRKFCKTMP*TNS LVLNVSGHSL**QKINFKKEFCKVSRILYHWMIC *SALCGRTVIKRGAF*FFSL

Frame 2

FSTEISWERASMHLQIVIELFY*MMTPKLS*NI ILALLVHLLCDLGQVTLLSFQFSFLTGR*S*KR L*STALHRVLFV*RADNKYESQGLGKPPSQPEL LEDKGFSFESAVPYLCICDRVPGT*EGLNKYVNL *ILGRLQP*QATAS*ISFL*SFNI*HLKGRRYL LWDKYPRYVL*NAQA*RNDSCLKGTISLSHRKA PQAWDLGPKATGKSLEREAHLPAL*LAGSHSTHA ARSSDWPRRHPSSRDYFVCWGGALRSSRSAGGL GCSGAALRSTALHRGRREFSESERHVERMKYRT IKLPTHITRRISLKDSLQDYQRE*FV*SIMC*NN RSLFTCALTRNRVTMFSIL*APGLQGSELKI*K CGHGLVPGVGLCSFFLPGGPCCFI*VVTWYEIM TILITLAENCPRFWQSLNA*NNRMKT*GEWPNLS GYQKALLIRGQL*EEYAF*KSSLLRPKNRLKIT RNRPEMVWGRIMKS*GGGLKMELKSSGFSYRVN *RN*RT*KEMNSKDMQMNFFWI*DIMKGL**RIY TTSVRQMEQVIGGKKRPKI*QNWFSGE*HIFRI PRTAAKPKSWCVISTKAVAMAVSSIMWSTAS*L HMAPSEHSSWNLRIGAMLLVDGRLYLGL*VRHAQ TDLASPLDTGQVK*RTKMFKWSSFPL*TVFIPV LHIYPWLYQKTSQIDLYECMVTLQCGGCLSLSN T*SAHSLG*KKK*KKPPRSLASNIQLLESMSDAQ TKWEQKLPSIPLKSTWCMLKNIFSFLHAECKWT KKECIWPQMTLLY*RRQKQSTPIMNLLVITLFP GQLDCTIDTQKIHFVE*SWIYIFSLRQTS*CVLF HPRSVELLMKLCKHYILMPLQTSIL*MTSTILG ARMPTIKLPFMLTNPELQMKFPWNLEISLVWLE IIGMAILKVSTGNWEGRAYIPPTKFERR*KRSST PHILRLRNKAQMEEINDQTQFDQTQFKPFQPNC R*RGL*SNKIRLYE*ILSAPRAAGN*HRLQLVE FLFNKGCNALIPMHSTIMYSHITCKQVVFYFAPF SMSP*DKHCHIV*FK*HRHFV*DLKHGAYI*ET CVNY*EDRNSSLL*GS*FLFDGGIVTTEFTPVN RFRMRMDVWFFFVFVFVFSFIRLSVFFFLNNCIS SLTSSLISEEYIRK*NIHSPLENFVKQCHEQIL *YSMFLDILFDNKK*ILKRNFVKFLEFYIIG*Y VDQPYVEEL**KEELFSFSA

Sequence NM_178155

CGTTTAGTACAGAAATCTCATGGGAGAGAGCATCCATGCATTTACAAATTGTTATTGAATTATTTTATTGAATGATGACACCCAAACTGAGCTAGAACAT AATTCTGGCTCTGCTAGTACATCTTCTGTGTGATCTTGGACAAGTCACTCTACTTTCCTTTCAATTTTCTTTTCTCACAGGGAGATAATCATAAAAACGA CTGTAAAGTACAGCACTTCATAGAGTGCTTTTTGTTTAAAGAGCTGACAATAAATACGAGTCTCAAGGTCTAGGAAAGCCTCCCTCACAACCTGAGCTGC TTGAGGACAAGGGATTTTCTTTTGAATCAGCAGTACCTTATTTGTGTATCTGTGATAGAGTTCCTGGTACATAAGAAGGTCTCAATAAATATGTGAATTT ATGAATATTAGGCAGATTGCAACCTTGACAGGCCACTGCCTCTTAAATCTCCTTTCTGTGATCTTTTAATATTTAACATCTAAAAGGCCGCCGCTACTTG CTTTGGGATAAGTATCCCCGGTATGTACTTTAAAATGCCCAAGCCTAGAGAAATGATTCTTGTCTTAAGGGCACCATTTCGCTCTCCCACCGTAAAGCGC CCCAGGCTTGGGATCTGGGTCCCAAGGCTACAGGGAAGAGTTTGGAACGGGAAGCTCATCTTCCGGCCCTCTGATTGGCCGGCTCGCACTCCACTCACGC GGCGCGCAGCTCTGATTGGCCTCGGCGGCACCCCTCGTCCCGCGACTACTTTGTGTGCTGGGGCGGCGCGCTCCGGTCCTCCCGCTCAGCTGGCGGTCTG GGCTGCTCTGGGGCAGCCCTTCGGTCCACTGCTCTGCATCGCGGGCGCCGGGAATTTTCCGAGTCCGAGCGGGTTGCTGCTTTTGCTCAGAGGACATCCA TGACCCTAATGGTCTTTTTGTTCAAGATAAAGTGATTTTTTGCCTTTGTTGATTAACTGGACAAATTCAGCATGTAGAGCGCATGAAGTACAGGACAATA AAGCTTCCTACACATATCACCAGGAGGATCTCTTTGAAAGATTCACTGCAGGACTACCAGAGAGAATAATTTGTCTGAAGCATCATGTGTTGAAACAACA GAAGTCTATTCACCTGTGCACTAACTAGAAACAGAGTTACAATGTTTTCAATTCTTTGAGCTCCAGGACTCCAGGGAAGTGAGTTGAAAATCTGAAAATG CGGCCATGGACTGGTTCCTGGCGTTGGATTATGCTCATTCTTTTTGCCTGGGGGACCTTGCTGTTTTATATAGGTGGTCACTTGGTACGAGATAATGACC ATCCTGATCACTCTAGCCGAGAACTGTCCAAGATTCTGGCAAAGCTTGAACGCTTAAAACAACAGAATGAAGACTTGAGGCGAATGGCCGAATCTCTCCG GATACCAGAAGGCCCTATTGATCAGGGGCCAGCTATAGGAAGAGTACGCGTTTTAGAAGAGCAGCTTGTTAAGGCCAAAGAACAGATTGAAAATTACAAG AAACAGACCAGAAATGGTCTGGGGAAGGATCATGAAATCCTGAGGAGGAGGATTGAAAATGGAGCTAAAGAGCTCTGGTTTTTCCTACAGAGTGAATTGA AGAAATTAAAGAACTTAGAAGGAAATGAACTCCAAAGACATGCAGATGAATTTCTTTTGGATTTAGGACATCATGAAAGGTCTATAATGACGGATCTATA CTACCTCAGTCAGACAGATGGAGCAGGTGATTGGCGGGAAAAAGAGGCCAAAGATCTGACAGAACTGGTTCAGCGGAGAATAACATATCTTCAGAATCCC AAGGACTGCAGCAAAGCCAAAAAGCTGGTGTGTAATATCAACAAAGGCTGTGGCTATGGCTGTCAGCTCCATCATGTGGTCTACTGCTTCATGATTGCAT ATGGCACCCAGCGAACACTCATCTTGGAATCTCAGAATTGGCGCTATGCTACTGGTGGATGGGAGACTGTATTTAGGCCTGTAAGTGAGACATGCACAGA CAGATCTGGCATCTCCACTGGACACTGGTCAGGTGAAGTGAAGGACAAAAATGTTCAAGTGGTCGAGCTTCCCATTGTAGACAGTCTTCATCCCCGTCCT CCATATTTACCCTTGGCTGTACCAGAAGACCTCGCAGATCGACTTGTACGAGTGCATGGTGACCCTGCAGTGTGGTGGGTGTCTCAGTTTGTCAAATACT TGATCCGCCCACAGCCTTGGCTAGAAAAAGAAATAGAAGAAGCCACCAAGAAGCTTGGCTTCAAACATCCAGTTATTGGAGTCCATGTCAGACGCACAGA CAAAGTGGGAACAGAAGCTGCCTTCCATCCCATTGAAGAGTACATGGTGCATGTTGAAGAACATTTTCAGCTTCTTGCACGCAGAATGCAAGTGGACAAA AAAAGAGTGTATTTGGCCACAGATGACCCTTCTTTATTAAAGGAGGCAAAAACAAAGTACCCCAATTATGAATTTATTAGTGATAACTCTATTTCCTGGT CAGCTGGACTGCACAATCGATACACAGAAAATTCACTTCGTGGAGTGATCCTGGATATACATTTTCTCTCTCAGGCAGACTTCCTAGTGTGTACTTTTTC ATCCCAGGTCTGTCGAGTTGCTTATGAAATTATGCAAACACTACATCCTGATGCCTCTGCAAACTTCCATTCTTTAGATGACATCTACTATTTTGGGGGC CAGAATGCCCACAATCAAATTGCCATTTATGCTCACCAACCCCGAACTGCAGATGAAATTCCCATGGAACCTGGAGATATCATTGGTGTGGCTGGAAATC ATTGGGATGGCTATTCTAAAGGTGTCAACAGGAAATTGGGAAGGACGGGCCTATATCCCTCCTACAAAGTTCGAGAGAAGATAGAAACGGTCAAGTACCC CACATATCCTGAGGCTGAGAAATAAAGCTCAGATGGAAGAGATAAACGACCAAACTCAGTTCGACCAAACTCAGTTCAAACCATTTCAGCCAAACTGTAG ATGAAGAGGGCTCTGATCTAACAAAATAAGGTTATATGAGTAGATACTCTCAGCACCAAGAGCAGCTGGGAACTGACATAGGCTTCAATTGGTGGAATTC CTCTTTAACAAGGGCTGCAATGCCCTCATACCCATGCACAGTACAATAATGTACTCACATATAACATGCAAACAGGTTGTTTTCTACTTTGCCCCTTTCA GTATGTCCCCATAAGACAAACACTGCCATATTGTGTAATTTAAGTGACACAGACATTTTGTGTGAGACTTAAAACATGGTGCCTATATCTGAGAGACCTG TGTGAACTATTGAGAAGATCGGAACAGCTCCTTACTCTGAGGAAGTTGATTCTTATTTGATGGTGGTATTGTGACCACTGAATTCACTCCAGTCAACAGA TTCAGAATGAGAATGGACGTTTGGTTTTTTTTTGTTTTTGTTTTTGTTTTTTCCTTTATAAGGTTGTCTGTTTTTTTTTTTTTAAATAATTGCATCAGTT CATTGACCTCATCATTAATAAGTGAAGAATACATCAGAAAATAAAATATTCACTCTCCATTAGAAAATTTTGTAAAACAATGCCATGAACAAATTCTTTA GTACTCAATGTTTCTGGACATTCTCTTTGATAACAAAAAATAAATTTTAAAAAGGAATTTTGTAAAGTTTCTAGAATTTTATATCATTGGATGATATGTT GATCAGCCTTATGTGGAAGAACTGTGATAAAAAGAGGAGCTTTTTAGTTTTTCAGCTTA

refseq_FUT8.F3 (forward primer)
refseq_FUT8.R3 (reverse primer)
Single exon skipping

Frame 0

RLVQKSHGREHPCIYKLLLNYFIE**HPN*ART *FWLC*YIFCVILDKSLYFPFNFLFSQGDNHKND CKVQHFIECFLFKELTINTSLKV*ESLPHNLSC LRTRDFLLNQQYLICVSVIEFLVHKKVSINM*I YEY*ADCNLDRPLPLKSPFCDLLIFNI*KAAATC FGISIPGMYFKMPKPREMILVLRAPFRSPTVKR PRLGIWVPRLQGRVWNGKLIFRPSDWPARTPLT RRAALIGLGGTPRPATTLCAGAARSGPPAQLAVW AALGQPFGPLLCIAGAGNFPSPSGLLLLLRGHP *P*WSFCSR*SDFLPLLINWTNSACRAHEVQDN KASYTYHQEDLFERFTAGLPERIICLKHHVLKQQ KSIHLCTN*KQSYNVFNSLSSRTPGK*VENLKM RPWTGSWRWIMLILFAWGTLLFYIGGHLVRDND HPDHSSRELSKILAKLERLKQQNEDLRRMAESLR IPEGPIDQGPAIGRVRVLEEQLVKAKEQIENYK KQTRNGLGKDHEILRRRIENGAKELWFFLQSEL KKLKNLEGNELQRHADEFLLDLGHHERSIMTDLY YLSQTDGAGDWREKEAKDLTELVQRRITYLQNP KDCSKAKKLVCNINKGCGYGCQLHHVVYCFMIA YGTQRTLILESQNWRYATGGWETVFRPVSETCTD RSGISTGHWSGEVKDKNVQVVELPIVDSLHPRP PYLPLAVPEDLADRLVRVHGDPAVWWVSQFVKY LIRPQPWLEKEIEEATKKLGFKHPVIGVHVRRTD KVGTEAAFHPIEEYMVHVEEHFQLLARRMQVDK KRVYLATDDPSLLKEAKTKYPNYEFISDNSISW SAGLHNRYTENSLRGVILDIHFLSQADFLVCTFS SQVCRVAYEIMQTLHPDASANFHSLDDIYYFGG QNAHNQIAIYAHQPRTADEIPMEPGDIIGVAGN HWDGYSKGVNRKLGRTGLYPSYKVREKIETVKYP TYPEAEK*SSDGRDKRPNSVRPNSVQTISAKL* MKRALI*QNKVI*VDTLSTKSSWELT*ASIGGI PL*QGLQCPHTHAQYNNVLTYNMQTGCFLLCPFQ YVPIRQTLPYCVI*VTQTFCVRLKTWCLYLRDL CELLRRSEQLLTLRKLILI*WWYCDH*IHSSQQ IQNENGRLVFFCFCFCFFLYKVVCFFFFK*LHQF IDLIINK*RIHQKIKYSLSIRKFCKTMP*TNSL VLNVSGHSL**QKINFKKEFCKVSRILYHWMIC *SALCGRTVIKRGAF*FFSL

Frame 1

V*YRNLMGESIHAFTNCY*IILLNDDTQTELEH NSGSASTSSV*SWTSHSTFLSIFFSHREIIIKT TVKYSTS*SAFCLKS*Q*IRVSRSRKASLTT*AA *GQGIFF*ISSTLFVYL**SSWYIRRSQ*ICEF MNIRQIATLTGHCLLNLLSVIF*YLTSKRPPLL ALG*VSPVCTLKCPSLEK*FLS*GHHFALPP*SA PGLGSGSQGYREEFGTGSSSSGPLIGRLALHSR GAQL*LASAAPLVPRLLCVLGRRAPVLPLSWRS GLLWGSPSVHCSASRAPGIFRVRAGCCFCSEDIH DPNGLFVQDKVIFCLC*LTGQIQHVERMKYRTI KLPTHITRRISLKDSLQDYQRE*FV*SIMC*NN RSLFTCALTRNRVTMFSIL*APGLQGSELKI*KC GHGLVPGVGLCSFFLPGGPCCFI*VVTWYEIMT ILITLAENCPRFWQSLNA*NNRMKT*GEWPNLS GYQKALLIRGQL*EEYAF*KSSLLRPKNRLKITR NRPEMVWGRIMKS*GGGLKMELKSSGFSYRVN* RN*RT*KEMNSKDMQMNFFWI*DIMKGL**RIY TTSVRQMEQVIGGKKRPKI*QNWFSGE*HIFRIP RTAAKPKSWCVISTKAVAMAVSSIMWSTAS*LH MAPSEHSSWNLRIGAMLLVDGRLYLGL*VRHAQ TDLASPLDTGQVK*RTKMFKWSSFPL*TVFIPVL HIYPWLYQKTSQIDLYECMVTLQCGGCLSLSNT *SAHSLG*KKK*KKPPRSLASNIQLLESMSDAQ TKWEQKLPSIPLKSTWCMLKNIFSFLHAECKWTK KECIWPQMTLLY*RRQKQSTPIMNLLVITLFPG QLDCTIDTQKIHFVE*SWIYIFSLRQTS*CVLF HPRSVELLMKLCKHYILMPLQTSIL*MTSTILGA RMPTIKLPFMLTNPELQMKFPWNLEISLVWLEI IGMAILKVSTGNWEGRAYIPPTKFERR*KRSST PHILRLRNKAQMEEINDQTQFDQTQFKPFQPNCR *RGL*SNKIRLYE*ILSAPRAAGN*HRLQLVEF LFNKGCNALIPMHSTIMYSHITCKQVVFYFAPF SMSP*DKHCHIV*FK*HRHFV*DLKHGAYI*ETC VNY*EDRNSSLL*GS*FLFDGGIVTTEFTPVNR FRMRMDVWFFFVFVFVFSFIRLSVFFFLNNCIS SLTSSLISEEYIRK*NIHSPLENFVKQCHEQIL* YSMFLDILFDNKK*ILKRNFVKFLEFYIIG*YV DQPYVEEL**KEELFSFSA

Frame 2

FSTEISWERASMHLQIVIELFY*MMTPKLS*NI ILALLVHLLCDLGQVTLLSFQFSFLTGR*S*KR L*STALHRVLFV*RADNKYESQGLGKPPSQPEL LEDKGFSFESAVPYLCICDRVPGT*EGLNKYVNL *ILGRLQP*QATAS*ISFL*SFNI*HLKGRRYL LWDKYPRYVL*NAQA*RNDSCLKGTISLSHRKA PQAWDLGPKATGKSLEREAHLPAL*LAGSHSTHA ARSSDWPRRHPSSRDYFVCWGGALRSSRSAGGL GCSGAALRSTALHRGRREFSESERVAAFAQRTS MTLMVFLFKIK*FFAFVD*LDKFSM*SA*STGQ* SFLHISPGGSL*KIHCRTTRENNLSEASCVETT EVYSPVH*LETELQCFQFFELQDSREVS*KSEN AAMDWFLALDYAHSFCLGDLAVLYRWSLGTR**P S*SL*PRTVQDSGKA*TLKTTE*RLEANGRISP DTRRPY*SGASYRKSTRFRRAAC*GQRTD*KLQ ETDQKWSGEGS*NPEEED*KWS*RALVFPTE*IE EIKELRRK*TPKTCR*ISFGFRTS*KVYNDGSI LPQSDRWSR*LAGKRGQRSDRTGSAENNISSES QGLQQSQKAGV*YQQRLWLWLSAPSCGLLLHDCI WHPANTHLGISELALCYWWMGDCI*ACK*DMHR QIWHLHWTLVR*SEGQKCSSGRASHCRQSSSPS SIFTLGCTRRPRRSTCTSAW*PCSVVGVSVCQIL DPPTALARKRNRRSHQEAWLQTSSYWSPCQTHR QSGNRSCLPSH*RVHGAC*RTFSASCTQNASGQ KKSVFGHR*PFFIKGGKNKVPQL*IY***LYFLV SWTAQSIHRKFTSWSDPGYTFSLSGRLPSVYFF IPGLSSCL*NYANTTS*CLCKLPFFR*HLLFWG PECPQSNCHLCSPTPNCR*NSHGTWRYHWCGWKS LGWLF*RCQQEIGKDGPISLLQSSREDRNGQVP HIS*G*EIKLRWKR*TTKLSSTKLSSNHFSQTV DEEGSDLTK*GYMSRYSQHQEQLGTDIGFNWWNS SLTRAAMPSYPCTVQ*CTHI*HANRLFSTLPLS VCPHKTNTAILCNLSDTDILCET*NMVPISERP V*TIEKIGTAPYSEEVDSYLMVVL*PLNSLQSTD SE*EWTFGFFLFLFLFFPL*GCLFFFF*IIASV H*PHH**VKNTSENKIFTLH*KIL*NNAMNKFF STQCFWTFSLITKNKF*KGIL*SF*NFISLDDML ISLMWKNCDKKRSFLVFQL