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Sequences

Sequence NM_024117

TCCGGAACGCCGGGGTGTGGTTCCGGGTCGTGTGCGGCTCGGGGTAATAGGGCTGCTGCTCGGCCGGCCGGCGGCGGCGAGCAGCAGGGGCATGAGGGCT
AACCCGGGAAGCGGCAGCTGAGCGGGCCGGGAGGAGCGCCGGTCCCCGTGGATCCCGAGAGTGCAGAGCTCGGGGCAGGGGCCGGGAGGCGTGGGGGAGC
CGGGCCCTCCCCTCAGGAACGTGTCCCGGGGCCGACCCGGCCCGTAGTGTGGAAGCAGCTTCAGGTAGGTGAGCTCGTGAAACAATATGAAGAGGAGAAA
ATAGCCTTTTAAGGAAATTGGCCCACAGAAAGGATGGCCTTCTTGGACAATCCAACTATCATTCTAGCTCATATTCGACAGTCACATGTGACCAGTGATG
ACACGGGAATGTGTGAGATGGTTCTCATTGATCATGATGTTGACCTAGAGAAGATTCATCCTCCTTCAATGCCTGGAGACAGTGGGTCAGAAATTCAGGG
AAGCAATGGTGAGACTCAGGGCTATGTATATGCCCAGTCAGTCGATATTACCTCAAGTTGGGACTTTGGTATTAGAAGACGCTCAAACACAGCTCAAAGA
TTAGAACGACTCCGAAAAGAGAGACAAAACCAGATCAAATGCAAAAATATTCAGTGGAAAGAAAGAAATTCTAAGCAATCAGCCCAGGAGTTAAAGTCAC
TGTTTGAAAAAAAATCTCTCAAAGAGAAGCCTCCAATTTCTGGGAAGCAGTCGATATTATCTGTACGCCTAGAACAGTGCCCTCTGCAGCTGAATAACCC
TTTTAACGAGTATTCCAAATTTGATGGCAAGGGTCATGTAGGTACAACAGCAACCAAGAAGATCGATGTCTACCTCCCTCTGCACTCGAGCCAGGACAGA
CTGCTGCCAATGACCGTGGTGACAATGGCCAGCGCCAGGGTGCAGGACCTGATCGGGCTCATCTGCTGGCAGTATACAAGCGAAGGACGGGAGCCGAAGC
TCAATGACAATGTCAGTGCCTACTGCCTGCATATTGCTGAGGATGATGGGGAGGTGGACACCGATTTCCCCCCGCTGGATTCCAATGAGCCCATTCATAA
GTTTGGCTTCAGTACTTTGGCCCTGGTTGAAAAGTACTCATCTCCTGGTCTGACATCCAAAGAGTCACTCTTTGTTCGAATAAATGCTGCTCATGGATTC
TCCCTTATTCAGGTGGACAACACAAAGGTTACCATGAAGGAAATCTTACTGAAGGCAGTGAAGCGAAGAAAAGGATCCCAGAAAGTTTCAGGTTCAAGGG
CAGACGGGGTTTTTGAGGAGGATTCGCAAATTGACATAGCCACAGTACAGGATATGCTTAGCAGCCACCATTACAAGTCATTCAAAGTCAGCATGATCCA
CAGACTGCGATTCACAACCGACGTACAGCTAGGTATCTCTGGAGACAAAGTAGAGATAGACCCTGTTACGAATCAGAAAGCCAGCACTAAGTTTTGGATT
AAGCAGAAACCCATCTCAATCGATTCCGACCTGCTCTGTGCCTGTGACCTTGCTGAAGAGAAAAGCCCCAGTCACGCAATATTTAAACTCACGTATCTAA
GCAATCACGACTATAAACACCTCTACTTTGAATCGGACGCTGCTACCGTCAATGAAATTGTGCTCAAGGTTAACTACATCCTGGAATCGCGAGCTAGCAC
TGCCCGGGCTGACTACTTTGCTCAAAAACAAAGAAAACTGAACAGACGTACGAGCTTCAGCTTCCAGAAGGAGAAGAAATCCGGGCAGCAGTGACACTGG
CCTCCAGCCTCAATCTGTTCCGTAGCTCAGAGCCTGCCTGCCAGGGCCAAGTGCCCTAGAGTCCACCCGGTGTCCTGAAGTCCTCGGGGGGAGGCCAGCC
CCTGGCTCACTGGCACAGGGCAGGTGGGCTCTCGGGGAAGGTGTCGGGGGCCCCCTAGGAGGGAGCGCTGGGGACATTGCCATGGGACGGAAGTCTGCTT
GGCAGTGGCTTTGATAAGCGATGCTTGGGGGTCAGACCACCCCCTAGAGGAGCCACGTGCCGCCCAGCCACCTTCAATGCCTGCCACCCTGCCCGAGGAT
GTACAGAGCCGTGCCCACACATTTCCTTGCAACTTGATCAAATTTCTTAAAGCAAACAACAAAAATGTACATTTCTGTTTTTCCTTTTAATAAACAGGTG
TACTCTTTATCATGGTTGGTATGATGGACCATTCTTTGGGGCGGAGGATTGATTATGTTACTCTCTTTAAAATCTGTTCCCATATTGAACAGGCAGATTG
GAAAAGCTATGGTTCGATTTCTCAGAAGAAATGTTTAGGTCTTAGTCAATAGTTTTAACTATGCCATTTGTTTAAATGAGTGCATTTGCTTCGAGGGTAG
TGTCTTACTAAAAGTTAGGAACAGAGACCTAGTGGTGTGTCCAAGGCCGTGTCACTTTCCCCTTCAGCACACCCCAGCTTCTGACCTCAGAGCCCAGGAG
CTGCGTGGACAGTGTGGGGTGCCAGGAGGAGGGGCGGTGGCTGGTCCTCAGGCACGCTGCACTCCCAGCCAGACATGGTCTTTCCGTTTCTTAAGTAGCA
AGTGTAGGTTTCAGCTGGCAGTTCCACCTGCATGTTCTCTGCTTCGCTGCCTTGGAAGGGGCCACATTCCCCATTCCTCTTCTCCTTACAGCGCCTGCCT
CCTTTTTCAAGCAGGCGGAAAGCTGCTGTTTCTCACGTTTCAGGGAGAGGGGTGAGCGGAGGGAGACCTGTGTCCGTGCCGTCCGGCTCCCTGGGTGGGA
ACAGGCAAGGGATCAGATGCCCCTGACACCACGCCTCTGGCCACACCAGATGCCTCTGCAGTCCTCGACAGCCTCTTCAGTGTCCCTCCTGCGGTGATGT
CCTTACTGTCCCCAGCCAGGGCCGGGGACCGGTGTTTCACTGAGGACCTGCATTAGAAACATTTTTTAAATTGTTGTACAGGAAGAGATGTGTCTAAAAC
AGCATCTTAAAGCTGAGTGTATTTCTTTGCACAAGGGGTCATGCTGATGAATTCTTCTTTCATTCTGATCTTTGTTCAGCCAACAGGAGCGTCCTTTTCT
AATGTCTTCCATTCCTACCCCCCACCCAAAAACAAAAGAAATATTTGTAGCTTGCTATCTGTATTTGAATTTTTAGCAATTTTATATTTAGATACTTTGA
AAAATGTAAATGACTAATTTGGTCATTAAATCTTGTGACATATTCGATATTAAAATGATATTAAAATAAAAGTCATATAAATACACA
  • refseq_MAPKAP1.F3 (forward primer)
  • refseq_MAPKAP1.R3 (reverse primer)
  • Single exon skipping

Frame 0

SGTPGCGSGSCAARGNRAAARPAGGGEQQGHEG
*PGKRQLSGPGGAPVPVDPESAELGAGAGRRGGA
GPSPQERVPGPTRPVVWKQLQVGELVKQYEEEK
IAF*GNWPTERMAFLDNPTIILAHIRQSHVTSD
DTGMCEMVLIDHDVDLEKIHPPSMPGDSGSEIQG
SNGETQGYVYAQSVDITSSWDFGIRRRSNTAQR
LERLRKERQNQIKCKNIQWKERNSKQSAQELKS
LFEKKSLKEKPPISGKQSILSVRLEQCPLQLNNP
FNEYSKFDGKGHVGTTATKKIDVYLPLHSSQDR
LLPMTVVTMASARVQDLIGLICWQYTSEGREPK
LNDNVSAYCLHIAEDDGEVDTDFPPLDSNEPIHK
FGFSTLALVEKYSSPGLTSKESLFVRINAAHGF
SLIQVDNTKVTMKEILLKAVKRRKGSQKVSGSR
ADGVFEEDSQIDIATVQDMLSSHHYKSFKVSMIH
RLRFTTDVQLGISGDKVEIDPVTNQKASTKFWI
KQKPISIDSDLLCACDLAEEKSPSHAIFKLTYL
SNHDYKHLYFESDAATVNEIVLKVNYILESRAST
ARADYFAQKQRKLNRRTSFSFQKEKKSGQQ*HW
PPASICSVAQSLPARAKCPRVHPVS*SPRGEAS
PWLTGTGQVGSRGRCRGPPRRERWGHCHGTEVCL
AVALISDAWGSDHPLEEPRAAQPPSMPATLPED
VQSRAHTFPCNLIKFLKANNKNVHFCFSF**TG
VLFIMVGMMDHSLGRRIDYVTLFKICSHIEQADW
KSYGSISQKKCLGLSQ*F*LCHLFK*VHLLRG*
CLTKS*EQRPSGVSKAVSLSPSAHPSF*PQSPG
AAWTVWGARRRGGGWSSGTLHSQPDMVFPFLK*Q
V*VSAGSSTCMFSASLPWKGPHSPFLFSLQRLP
PFSSRRKAAVSHVSGRGVSGGRPVSVPSGSLGG
NRQGIRCP*HHASGHTRCLCSPRQPLQCPSCGDV
LTVPSQGRGPVFH*GPALETFFKLLYRKRCV*N
SILKLSVFLCTRGHADEFFFHSDLCSANRSVLF
*CLPFLPPTQKQKKYL*LAICI*IFSNFIFRYFE
KCK*LIWSLNLVTYSILK*Y*NKSHINT

Frame 1

PERRGVVPGRVRLGVIGLLLGRPAAASSRGMRA
NPGSGS*AGREERRSPWIPRVQSSGQGPGGVGE
PGPPLRNVSRGRPGP*CGSSFR*VSS*NNMKRRK
*PFKEIGPQKGWPSWTIQLSF*LIFDSHM*PVM
TRECVRWFSLIMMLT*RRFILLQCLETVGQKFR
EAMVRLRAMYMPSQSILPQVGTLVLEDAQTQLKD
*NDSEKRDKTRSNAKIFSGKKEILSNQPRS*SH
CLKKNLSKRSLQFLGSSRYYLYA*NSALCS*IT
LLTSIPNLMARVM*VQQQPRRSMSTSLCTRARTD
CCQ*PW*QWPAPGCRT*SGSSAGSIQAKDGSRS
SMTMSVPTACILLRMMGRWTPISPRWIPMSPFI
SLASVLWPWLKSTHLLV*HPKSHSLFE*MLLMDS
PLFRWTTQRLP*RKSY*RQ*SEEKDPRKFQVQG
QTGFLRRIRKLT*PQYRICLAATITSHSKSA*S
TDCDSQPTYS*VSLETK*R*TLLRIRKPALSFGL
SRNPSQSIPTCSVPVTLLKRKAPVTQYLNSRI*
AITTINTSTLNRTLLPSMKLCSRLTTSWNRELA
LPGLTTLLKNKEN*TDVRASASRRRRNPGSSDTG
LQPQSVP*LRACLPGPSALESTRCPEVLGGRPA
PGSLAQGRWALGEGVGGPLGGSAGDIAMGRKSA
WQWL**AMLGGQTTP*RSHVPPSHLQCLPPCPRM
YRAVPTHFLAT*SNFLKQTTKMYISVFPFNKQV
YSLSWLV*WTILWGGGLIMLLSLKSVPILNRQI
GKAMVRFLRRNV*VLVNSFNYAICLNECICFEGS
VLLKVRNRDLVVCPRPCHFPLQHTPASDLRAQE
LRGQCGVPGGGAVAGPQARCTPSQTWSFRFLSS
KCRFQLAVPPACSLLRCLGRGHIPHSSSPYSACL
LFQAGGKLLFLTFQGEG*AEGDLCPCRPAPWVG
TGKGSDAPDTTPLATPDASAVLDSLFSVPPAVM
SLLSPARAGDRCFTEDLH*KHFLNCCTGRDVSKT
AS*S*VYFFAQGVMLMNSSFILIFVQPTGASFS
NVFHSYPPPKNKRNICSLLSVFEFLAILYLDTL
KNVND*FGH*IL*HIRY*NDIKIKVI*IH

Frame 2

RNAGVWFRVVCGSG**GCCSAGRRRRAAGA*GL
TREAAAERAGRSAGPRGSRECRARGRGREAWGS
RALPSGTCPGADPARSVEAASGR*ARETI*RGE
NSLLRKLAHRKDGLLGQSNYHSSSYSTVTCDQ**
HGNV*DGSH*S*C*PREDSSSFNAWRQWVRNSG
KQW*DSGLCICPVSRYYLKLGLWY*KTLKHSSK
IRTTPKRETKPDQMQKYSVERKKF*AISPGVKVT
V*KKISQREASNFWEAVDIICTPRTVPSAAE*P
F*RVFQI*WQGSCRYNSNQEDRCLPPSALEPGQ
TAANDRGDNGQRQGAGPDRAHLLAVYKRRTGAEA
Q*QCQCLLPAYC*G*WGGGHRFPPAGFQ*AHS*
VWLQYFGPG*KVLISWSDIQRVTLCSNKCCSWI
LPYSGGQHKGYHEGNLTEGSEAKKRIPESFRFKG
RRGF*GGFAN*HSHSTGYA*QPPLQVIQSQHDP
QTAIHNRRTARYLWRQSRDRPCYESESQH*VLD
*AETHLNRFRPALCL*PC*REKPQSRNI*THVSK
QSRL*TPLL*IGRCYRQ*NCAQG*LHPGIAS*H
CPG*LLCSKTKKTEQTYELQLPEGEEIRAAVTL
ASSLNLFRSSEPACQGQVP*SPPGVLKSSGGGQP
LAHWHRAGGLSGKVSGAP*EGALGTLPWDGSLL
GSGFDKRCLGVRPPPRGATCRPATFNACHPARG
CTEPCPHISLQLDQIS*SKQQKCTFLFFLLINRC
TLYHGWYDGPFFGAED*LCYSL*NLFPY*TGRL
EKLWFDFSEEMFRS*SIVLTMPFV*MSAFASRV
VSY*KLGTET*WCVQGRVTFPFSTPQLLTSEPRS
CVDSVGCQEEGRWLVLRHAALPARHGLSVS*VA
SVGFSWQFHLHVLCFAALEGATFPIPLLLTAPA
SFFKQAESCCFSRFRERGERRETCVRAVRLPGWE
QARDQMPLTPRLWPHQMPLQSSTASSVSLLR*C
PYCPQPGPGTGVSLRTCIRNIF*IVVQEEMCLK
QHLKAECISLHKGSC**ILLSF*SLFSQQERPFL
MSSIPTPHPKTKEIFVACYLYLNF*QFYI*IL*
KM*MTNLVIKSCDIFDIKMILK*KSYKYT

Sequence NM_001006620

TCCGGAACGCCGGGGTGTGGTTCCGGGTCGTGTGCGGCTCGGGGTAATAGGGCTGCTGCTCGGCCGGCCGGCGGCGGCGAGCAGCAGGGGCATGAGGGCT
AACCCGGGAAGCGGCAGCTGAGCGGGCCGGGAGGAGCGCCGGTCCCCGTGGATCCCGAGAGTGCAGAGCTCGGGGCAGGGGCCGGGAGGCGTGGGGGAGC
CGGGCCCTCCCCTCAGGAACGTGTCCCGGGGCCGACCCGGCCCGTAGTGTGGAAGCAGCTTCAGCTCAAAGATTAGAACGACTCCGAAAAGAGAGACAAA
ACCAGATCAAATGCAAAAATATTCAGTGGAAAGAAAGAAATTCTAAGCAATCAGCCCAGGAGTTAAAGTCACTGTTTGAAAAAAAATCTCTCAAAGAGAA
GCCTCCAATTTCTGGGAAGCAGTCGATATTATCTGTACGCCTAGAACAGTGCCCTCTGCAGCTGAATAACCCTTTTAACGAGTATTCCAAATTTGATGGC
AAGGGTCATGTAGGTACAACAGCAACCAAGAAGATCGATGTCTACCTCCCTCTGCACTCGAGCCAGGACAGACTGCTGCCAATGACCGTGGTGACAATGG
CCAGCGCCAGGGTGCAGGACCTGATCGGGCTCATCTGCTGGCAGTATACAAGCGAAGGACGGGAGCCGAAGCTCAATGACAATGTCAGTGCCTACTGCCT
GCATATTGCTGAGGATGATGGGGAGGTGGACACCGATTTCCCCCCGCTGGATTCCAATGAGCCCATTCATAAGTTTGGCTTCAGTACTTTGGCCCTGGTT
GAAAAGTACTCATCTCCTGGTCTGACATCCAAAGAGTCACTCTTTGTTCGAATAAATGCTGCTCATGGATTCTCCCTTATTCAGGTGGACAACACAAAGG
TTACCATGAAGGAAATCTTACTGAAGGCAGTGAAGCGAAGAAAAGGATCCCAGAAAGTTTCAGGCCCTCAGTACCGCCTGGAGAAGCAGAGCGAGCCCAA
TGTCGCCGTTGACCTGGACAGCACTTTGGAGAGCCAGAGCGCATGGGAGTTCTGCCTGGTCCGCGAGAACAGTTCAAGGGCAGACGGGGTTTTTGAGGAG
GATTCGCAAATTGACATAGCCACAGTACAGGATATGCTTAGCAGCCACCATTACAAGTCATTCAAAGTCAGCATGATCCACAGACTGCGATTCACAACCG
ACGTACAGCTAGGTATCTCTGGAGACAAAGTAGAGATAGACCCTGTTACGAATCAGAAAGCCAGCACTAAGTTTTGGATTAAGCAGAAACCCATCTCAAT
CGATTCCGACCTGCTCTGTGCCTGTGACCTTGCTGAAGAGAAAAGCCCCAGTCACGCAATATTTAAACTCACGTATCTAAGCAATCACGACTATAAACAC
CTCTACTTTGAATCGGACGCTGCTACCGTCAATGAAATTGTGCTCAAGGTTAACTACATCCTGGAATCGCGAGCTAGCACTGCCCGGGCTGACTACTTTG
CTCAAAAACAAAGAAAACTGAACAGACGTACGAGCTTCAGCTTCCAGAAGGAGAAGAAATCCGGGCAGCAGTGACACTGGCCTCCAGCCTCAATCTGTTC
CGTAGCTCAGAGCCTGCCTGCCAGGGCCAAGTGCCCTAGAGTCCACCCGGTGTCCTGAAGTCCTCGGGGGGAGGCCAGCCCCTGGCTCACTGGCACAGGG
CAGGTGGGCTCTCGGGGAAGGTGTCGGGGGCCCCCTAGGAGGGAGCGCTGGGGACATTGCCATGGGACGGAAGTCTGCTTGGCAGTGGCTTTGATAAGCG
ATGCTTGGGGGTCAGACCACCCCCTAGAGGAGCCACGTGCCGCCCAGCCACCTTCAATGCCTGCCACCCTGCCCGAGGATGTACAGAGCCGTGCCCACAC
ATTTCCTTGCAACTTGATCAAATTTCTTAAAGCAAACAACAAAAATGTACATTTCTGTTTTTCCTTTTAATAAACAGGTGTACTCTTTATCATGGTTGGT
ATGATGGACCATTCTTTGGGGCGGAGGATTGATTATGTTACTCTCTTTAAAATCTGTTCCCATATTGAACAGGCAGATTGGAAAAGCTATGGTTCGATTT
CTCAGAAGAAATGTTTAGGTCTTAGTCAATAGTTTTAACTATGCCATTTGTTTAAATGAGTGCATTTGCTTCGAGGGTAGTGTCTTACTAAAAGTTAGGA
ACAGAGACCTAGTGGTGTGTCCAAGGCCGTGTCACTTTCCCCTTCAGCACACCCCAGCTTCTGACCTCAGAGCCCAGGAGCTGCGTGGACAGTGTGGGGT
GCCAGGAGGAGGGGCGGTGGCTGGTCCTCAGGCACGCTGCACTCCCAGCCAGACATGGTCTTTCCGTTTCTTAAGTAGCAAGTGTAGGTTTCAGCTGGCA
GTTCCACCTGCATGTTCTCTGCTTCGCTGCCTTGGAAGGGGCCACATTCCCCATTCCTCTTCTCCTTACAGCGCCTGCCTCCTTTTTCAAGCAGGCGGAA
AGCTGCTGTTTCTCACGTTTCAGGGAGAGGGGTGAGCGGAGGGAGACCTGTGTCCGTGCCGTCCGGCTCCCTGGGTGGGAACAGGCAAGGGATCAGATGC
CCCTGACACCACGCCTCTGGCCACACCAGATGCCTCTGCAGTCCTCGACAGCCTCTTCAGTGTCCCTCCTGCGGTGATGTCCTTACTGTCCCCAGCCAGG
GCCGGGGACCGGTGTTTCACTGAGGACCTGCATTAGAAACATTTTTTAAATTGTTGTACAGGAAGAGATGTGTCTAAAACAGCATCTTAAAGCTGAGTGT
ATTTCTTTGCACAAGGGGTCATGCTGATGAATTCTTCTTTCATTCTGATCTTTGTTCAGCCAACAGGAGCGTCCTTTTCTAATGTCTTCCATTCCTACCC
CCCACCCAAAAACAAAAGAAATATTTGTAGCTTGCTATCTGTATTTGAATTTTTAGCAATTTTATATTTAGATACTTTGAAAAATGTAAATGACTAATTT
GGTCATTAAATCTTGTGACATATTCGATATTAAAATGATATTAAAATAAAAGTCATATAAATACACA
  • refseq_MAPKAP1.F3 (forward primer)
  • refseq_MAPKAP1.R3 (reverse primer)
  • Single exon skipping

Frame 0

SGTPGCGSGSCAARGNRAAARPAGGGEQQGHEG
*PGKRQLSGPGGAPVPVDPESAELGAGAGRRGGA
GPSPQERVPGPTRPVVWKQLQLKD*NDSEKRDK
TRSNAKIFSGKKEILSNQPRS*SHCLKKNLSKR
SLQFLGSSRYYLYA*NSALCS*ITLLTSIPNLMA
RVM*VQQQPRRSMSTSLCTRARTDCCQ*PW*QW
PAPGCRT*SGSSAGSIQAKDGSRSSMTMSVPTA
CILLRMMGRWTPISPRWIPMSPFISLASVLWPWL
KSTHLLV*HPKSHSLFE*MLLMDSPLFRWTTQR
LP*RKSY*RQ*SEEKDPRKFQALSTAWRSRASP
MSPLTWTALWRARAHGSSAWSARTVQGQTGFLRR
IRKLT*PQYRICLAATITSHSKSA*STDCDSQP
TYS*VSLETK*R*TLLRIRKPALSFGLSRNPSQ
SIPTCSVPVTLLKRKAPVTQYLNSRI*AITTINT
STLNRTLLPSMKLCSRLTTSWNRELALPGLTTL
LKNKEN*TDVRASASRRRRNPGSSDTGLQPQSV
P*LRACLPGPSALESTRCPEVLGGRPAPGSLAQG
RWALGEGVGGPLGGSAGDIAMGRKSAWQWL**A
MLGGQTTP*RSHVPPSHLQCLPPCPRMYRAVPT
HFLAT*SNFLKQTTKMYISVFPFNKQVYSLSWLV
*WTILWGGGLIMLLSLKSVPILNRQIGKAMVRF
LRRNV*VLVNSFNYAICLNECICFEGSVLLKVR
NRDLVVCPRPCHFPLQHTPASDLRAQELRGQCGV
PGGGAVAGPQARCTPSQTWSFRFLSSKCRFQLA
VPPACSLLRCLGRGHIPHSSSPYSACLLFQAGG
KLLFLTFQGEG*AEGDLCPCRPAPWVGTGKGSDA
PDTTPLATPDASAVLDSLFSVPPAVMSLLSPAR
AGDRCFTEDLH*KHFLNCCTGRDVSKTAS*S*V
YFFAQGVMLMNSSFILIFVQPTGASFSNVFHSYP
PPKNKRNICSLLSVFEFLAILYLDTLKNVND*F
GH*IL*HIRY*NDIKIKVI*IH

Frame 1

PERRGVVPGRVRLGVIGLLLGRPAAASSRGMRA
NPGSGS*AGREERRSPWIPRVQSSGQGPGGVGE
PGPPLRNVSRGRPGP*CGSSFSSKIRTTPKRETK
PDQMQKYSVERKKF*AISPGVKVTV*KKISQRE
ASNFWEAVDIICTPRTVPSAAE*PF*RVFQI*W
QGSCRYNSNQEDRCLPPSALEPGQTAANDRGDNG
QRQGAGPDRAHLLAVYKRRTGAEAQ*QCQCLLP
AYC*G*WGGGHRFPPAGFQ*AHS*VWLQYFGPG
*KVLISWSDIQRVTLCSNKCCSWILPYSGGQHKG
YHEGNLTEGSEAKKRIPESFRPSVPPGEAERAQ
CRR*PGQHFGEPERMGVLPGPREQFKGRRGF*G
GFAN*HSHSTGYA*QPPLQVIQSQHDPQTAIHNR
RTARYLWRQSRDRPCYESESQH*VLD*AETHLN
RFRPALCL*PC*REKPQSRNI*THVSKQSRL*T
PLL*IGRCYRQ*NCAQG*LHPGIAS*HCPG*LLC
SKTKKTEQTYELQLPEGEEIRAAVTLASSLNLF
RSSEPACQGQVP*SPPGVLKSSGGGQPLAHWHR
AGGLSGKVSGAP*EGALGTLPWDGSLLGSGFDKR
CLGVRPPPRGATCRPATFNACHPARGCTEPCPH
ISLQLDQIS*SKQQKCTFLFFLLINRCTLYHGW
YDGPFFGAED*LCYSL*NLFPY*TGRLEKLWFDF
SEEMFRS*SIVLTMPFV*MSAFASRVVSY*KLG
TET*WCVQGRVTFPFSTPQLLTSEPRSCVDSVG
CQEEGRWLVLRHAALPARHGLSVS*VASVGFSWQ
FHLHVLCFAALEGATFPIPLLLTAPASFFKQAE
SCCFSRFRERGERRETCVRAVRLPGWEQARDQM
PLTPRLWPHQMPLQSSTASSVSLLR*CPYCPQPG
PGTGVSLRTCIRNIF*IVVQEEMCLKQHLKAEC
ISLHKGSC**ILLSF*SLFSQQERPFLMSSIPT
PHPKTKEIFVACYLYLNF*QFYI*IL*KM*MTNL
VIKSCDIFDIKMILK*KSYKYT

Frame 2

RNAGVWFRVVCGSG**GCCSAGRRRRAAGA*GL
TREAAAERAGRSAGPRGSRECRARGRGREAWGS
RALPSGTCPGADPARSVEAASAQRLERLRKERQ
NQIKCKNIQWKERNSKQSAQELKSLFEKKSLKEK
PPISGKQSILSVRLEQCPLQLNNPFNEYSKFDG
KGHVGTTATKKIDVYLPLHSSQDRLLPMTVVTM
ASARVQDLIGLICWQYTSEGREPKLNDNVSAYCL
HIAEDDGEVDTDFPPLDSNEPIHKFGFSTLALV
EKYSSPGLTSKESLFVRINAAHGFSLIQVDNTK
VTMKEILLKAVKRRKGSQKVSGPQYRLEKQSEPN
VAVDLDSTLESQSAWEFCLVRENSSRADGVFEE
DSQIDIATVQDMLSSHHYKSFKVSMIHRLRFTT
DVQLGISGDKVEIDPVTNQKASTKFWIKQKPISI
DSDLLCACDLAEEKSPSHAIFKLTYLSNHDYKH
LYFESDAATVNEIVLKVNYILESRASTARADYF
AQKQRKLNRRTSFSFQKEKKSGQQ*HWPPASICS
VAQSLPARAKCPRVHPVS*SPRGEASPWLTGTG
QVGSRGRCRGPPRRERWGHCHGTEVCLAVALIS
DAWGSDHPLEEPRAAQPPSMPATLPEDVQSRAHT
FPCNLIKFLKANNKNVHFCFSF**TGVLFIMVG
MMDHSLGRRIDYVTLFKICSHIEQADWKSYGSI
SQKKCLGLSQ*F*LCHLFK*VHLLRG*CLTKS*E
QRPSGVSKAVSLSPSAHPSF*PQSPGAAWTVWG
ARRRGGGWSSGTLHSQPDMVFPFLK*QV*VSAG
SSTCMFSASLPWKGPHSPFLFSLQRLPPFSSRRK
AAVSHVSGRGVSGGRPVSVPSGSLGGNRQGIRC
P*HHASGHTRCLCSPRQPLQCPSCGDVLTVPSQ
GRGPVFH*GPALETFFKLLYRKRCV*NSILKLSV
FLCTRGHADEFFFHSDLCSANRSVLF*CLPFLP
PTQKQKKYL*LAICI*IFSNFIFRYFEKCK*LI
WSLNLVTYSILK*Y*NKSHINT

Sequence NM_001006617

TCCGGAACGCCGGGGTGTGGTTCCGGGTCGTGTGCGGCTCGGGGTAATAGGGCTGCTGCTCGGCCGGCCGGCGGCGGCGAGCAGCAGGGGCATGAGGGCT
AACCCGGGAAGCGGCAGCTGAGCGGGCCGGGAGGAGCGCCGGTCCCCGTGGATCCCGAGAGTGCAGAGCTCGGGGCAGGGGCCGGGAGGCGTGGGGGAGC
CGGGCCCTCCCCTCAGGAACGTGTCCCGGGGCCGACCCGGCCCGTAGTGTGGAAGCAGCTTCAGGTAGGTGAGCTCGTGAAACAATATGAAGAGGAGAAA
ATAGCCTTTTAAGGAAATTGGCCCACAGAAAGGATGGCCTTCTTGGACAATCCAACTATCATTCTAGCTCATATTCGACAGTCACATGTGACCAGTGATG
ACACGGGAATGTGTGAGATGGTTCTCATTGATCATGATGTTGACCTAGAGAAGATTCATCCTCCTTCAATGCCTGGAGACAGTGGGTCAGAAATTCAGGG
AAGCAATGGTGAGACTCAGGGCTATGTATATGCCCAGTCAGTCGATATTACCTCAAGTTGGGACTTTGGTATTAGAAGACGCTCAAACACAGCTCAAAGA
TTAGAACGACTCCGAAAAGAGAGACAAAACCAGATCAAATGCAAAAATATTCAGTGGAAAGAAAGAAATTCTAAGCAATCAGCCCAGGAGTTAAAGTCAC
TGTTTGAAAAAAAATCTCTCAAAGAGAAGCCTCCAATTTCTGGGAAGCAGTCGATATTATCTGTACGCCTAGAACAGTGCCCTCTGCAGCTGAATAACCC
TTTTAACGAGTATTCCAAATTTGATGGCAAGGGTCATGTAGGTACAACAGCAACCAAGAAGATCGATGTCTACCTCCCTCTGCACTCGAGCCAGGACAGA
CTGCTGCCAATGACCGTGGTGACAATGGCCAGCGCCAGGGTGCAGGACCTGATCGGGCTCATCTGCTGGCAGTATACAAGCGAAGGACGGGAGCCGAAGC
TCAATGACAATGTCAGTGCCTACTGCCTGCATATTGCTGAGGATGATGGGGAGGTGGACACCGATTTCCCCCCGCTGGATTCCAATGAGCCCATTCATAA
GTTTGGCTTCAGTACTTTGGCCCTGGTTGAAAAGTACTCATCTCCTGGTCTGACATCCAAAGAGTCACTCTTTGTTCGAATAAATGCTGCTCATGGATTC
TCCCTTATTCAGGTGGACAACACAAAGGTTACCATGAAGGAAATCTTACTGAAGGCAGTGAAGCGAAGAAAAGGATCCCAGAAAGTTTCAGGCCCTCAGT
ACCGCCTGGAGAAGCAGAGCGAGCCCAATGTCGCCGTTGACCTGGACAGCACTTTGGAGAGCCAGAGCGCATGGGAGTTCTGCCTGGTCCGCGAGAACAG
TTCAAGGGCAGACGGGGTTTTTGAGGAGGATTCGCAAATTGACATAGCCACAGTACAGGATATGCTTAGCAGCCACCATTACAAGTCATTCAAAGTCAGC
ATGATCCACAGACTGCGATTCACAACCGACGTACAGCTAGGTATCTCTGGAGACAAAGTAGAGATAGACCCTGTTACGAATCAGAAAGCCAGCACTAAGT
TTTGGATTAAGCAGAAACCCATCTCAATCGATTCCGACCTGCTCTGTGCCTGTGACCTTGCTGAAGAGAAAAGCCCCAGTCACGCAATATTTAAACTCAC
GTATCTAAGCAATCACGACTATAAACACCTCTACTTTGAATCGGACGCTGCTACCGTCAATGAAATTGTGCTCAAGGTTAACTACATCCTGGAATCGCGA
GCTAGCACTGCCCGGGCTGACTACTTTGCTCAAAAACAAAGAAAACTGAACAGACGTACGAGCTTCAGCTTCCAGAAGGAGAAGAAATCCGGGCAGCAGT
GACACTGGCCTCCAGCCTCAATCTGTTCCGTAGCTCAGAGCCTGCCTGCCAGGGCCAAGTGCCCTAGAGTCCACCCGGTGTCCTGAAGTCCTCGGGGGGA
GGCCAGCCCCTGGCTCACTGGCACAGGGCAGGTGGGCTCTCGGGGAAGGTGTCGGGGGCCCCCTAGGAGGGAGCGCTGGGGACATTGCCATGGGACGGAA
GTCTGCTTGGCAGTGGCTTTGATAAGCGATGCTTGGGGGTCAGACCACCCCCTAGAGGAGCCACGTGCCGCCCAGCCACCTTCAATGCCTGCCACCCTGC
CCGAGGATGTACAGAGCCGTGCCCACACATTTCCTTGCAACTTGATCAAATTTCTTAAAGCAAACAACAAAAATGTACATTTCTGTTTTTCCTTTTAATA
AACAGGTGTACTCTTTATCATGGTTGGTATGATGGACCATTCTTTGGGGCGGAGGATTGATTATGTTACTCTCTTTAAAATCTGTTCCCATATTGAACAG
GCAGATTGGAAAAGCTATGGTTCGATTTCTCAGAAGAAATGTTTAGGTCTTAGTCAATAGTTTTAACTATGCCATTTGTTTAAATGAGTGCATTTGCTTC
GAGGGTAGTGTCTTACTAAAAGTTAGGAACAGAGACCTAGTGGTGTGTCCAAGGCCGTGTCACTTTCCCCTTCAGCACACCCCAGCTTCTGACCTCAGAG
CCCAGGAGCTGCGTGGACAGTGTGGGGTGCCAGGAGGAGGGGCGGTGGCTGGTCCTCAGGCACGCTGCACTCCCAGCCAGACATGGTCTTTCCGTTTCTT
AAGTAGCAAGTGTAGGTTTCAGCTGGCAGTTCCACCTGCATGTTCTCTGCTTCGCTGCCTTGGAAGGGGCCACATTCCCCATTCCTCTTCTCCTTACAGC
GCCTGCCTCCTTTTTCAAGCAGGCGGAAAGCTGCTGTTTCTCACGTTTCAGGGAGAGGGGTGAGCGGAGGGAGACCTGTGTCCGTGCCGTCCGGCTCCCT
GGGTGGGAACAGGCAAGGGATCAGATGCCCCTGACACCACGCCTCTGGCCACACCAGATGCCTCTGCAGTCCTCGACAGCCTCTTCAGTGTCCCTCCTGC
GGTGATGTCCTTACTGTCCCCAGCCAGGGCCGGGGACCGGTGTTTCACTGAGGACCTGCATTAGAAACATTTTTTAAATTGTTGTACAGGAAGAGATGTG
TCTAAAACAGCATCTTAAAGCTGAGTGTATTTCTTTGCACAAGGGGTCATGCTGATGAATTCTTCTTTCATTCTGATCTTTGTTCAGCCAACAGGAGCGT
CCTTTTCTAATGTCTTCCATTCCTACCCCCCACCCAAAAACAAAAGAAATATTTGTAGCTTGCTATCTGTATTTGAATTTTTAGCAATTTTATATTTAGA
TACTTTGAAAAATGTAAATGACTAATTTGGTCATTAAATCTTGTGACATATTCGATATTAAAATGATATTAAAATAAAAGTCATATAAATACACA
  • refseq_MAPKAP1.F3 (forward primer)
  • refseq_MAPKAP1.R3 (reverse primer)
  • Single exon skipping

Frame 0

SGTPGCGSGSCAARGNRAAARPAGGGEQQGHEG
*PGKRQLSGPGGAPVPVDPESAELGAGAGRRGGA
GPSPQERVPGPTRPVVWKQLQVGELVKQYEEEK
IAF*GNWPTERMAFLDNPTIILAHIRQSHVTSD
DTGMCEMVLIDHDVDLEKIHPPSMPGDSGSEIQG
SNGETQGYVYAQSVDITSSWDFGIRRRSNTAQR
LERLRKERQNQIKCKNIQWKERNSKQSAQELKS
LFEKKSLKEKPPISGKQSILSVRLEQCPLQLNNP
FNEYSKFDGKGHVGTTATKKIDVYLPLHSSQDR
LLPMTVVTMASARVQDLIGLICWQYTSEGREPK
LNDNVSAYCLHIAEDDGEVDTDFPPLDSNEPIHK
FGFSTLALVEKYSSPGLTSKESLFVRINAAHGF
SLIQVDNTKVTMKEILLKAVKRRKGSQKVSGPQ
YRLEKQSEPNVAVDLDSTLESQSAWEFCLVRENS
SRADGVFEEDSQIDIATVQDMLSSHHYKSFKVS
MIHRLRFTTDVQLGISGDKVEIDPVTNQKASTK
FWIKQKPISIDSDLLCACDLAEEKSPSHAIFKLT
YLSNHDYKHLYFESDAATVNEIVLKVNYILESR
ASTARADYFAQKQRKLNRRTSFSFQKEKKSGQQ
*HWPPASICSVAQSLPARAKCPRVHPVS*SPRGE
ASPWLTGTGQVGSRGRCRGPPRRERWGHCHGTE
VCLAVALISDAWGSDHPLEEPRAAQPPSMPATL
PEDVQSRAHTFPCNLIKFLKANNKNVHFCFSF**
TGVLFIMVGMMDHSLGRRIDYVTLFKICSHIEQ
ADWKSYGSISQKKCLGLSQ*F*LCHLFK*VHLL
RG*CLTKS*EQRPSGVSKAVSLSPSAHPSF*PQS
PGAAWTVWGARRRGGGWSSGTLHSQPDMVFPFL
K*QV*VSAGSSTCMFSASLPWKGPHSPFLFSLQ
RLPPFSSRRKAAVSHVSGRGVSGGRPVSVPSGSL
GGNRQGIRCP*HHASGHTRCLCSPRQPLQCPSC
GDVLTVPSQGRGPVFH*GPALETFFKLLYRKRC
V*NSILKLSVFLCTRGHADEFFFHSDLCSANRSV
LF*CLPFLPPTQKQKKYL*LAICI*IFSNFIFR
YFEKCK*LIWSLNLVTYSILK*Y*NKSHINT

Frame 1

PERRGVVPGRVRLGVIGLLLGRPAAASSRGMRA
NPGSGS*AGREERRSPWIPRVQSSGQGPGGVGE
PGPPLRNVSRGRPGP*CGSSFR*VSS*NNMKRRK
*PFKEIGPQKGWPSWTIQLSF*LIFDSHM*PVM
TRECVRWFSLIMMLT*RRFILLQCLETVGQKFR
EAMVRLRAMYMPSQSILPQVGTLVLEDAQTQLKD
*NDSEKRDKTRSNAKIFSGKKEILSNQPRS*SH
CLKKNLSKRSLQFLGSSRYYLYA*NSALCS*IT
LLTSIPNLMARVM*VQQQPRRSMSTSLCTRARTD
CCQ*PW*QWPAPGCRT*SGSSAGSIQAKDGSRS
SMTMSVPTACILLRMMGRWTPISPRWIPMSPFI
SLASVLWPWLKSTHLLV*HPKSHSLFE*MLLMDS
PLFRWTTQRLP*RKSY*RQ*SEEKDPRKFQALS
TAWRSRASPMSPLTWTALWRARAHGSSAWSART
VQGQTGFLRRIRKLT*PQYRICLAATITSHSKSA
*STDCDSQPTYS*VSLETK*R*TLLRIRKPALS
FGLSRNPSQSIPTCSVPVTLLKRKAPVTQYLNS
RI*AITTINTSTLNRTLLPSMKLCSRLTTSWNRE
LALPGLTTLLKNKEN*TDVRASASRRRRNPGSS
DTGLQPQSVP*LRACLPGPSALESTRCPEVLGG
RPAPGSLAQGRWALGEGVGGPLGGSAGDIAMGRK
SAWQWL**AMLGGQTTP*RSHVPPSHLQCLPPC
PRMYRAVPTHFLAT*SNFLKQTTKMYISVFPFN
KQVYSLSWLV*WTILWGGGLIMLLSLKSVPILNR
QIGKAMVRFLRRNV*VLVNSFNYAICLNECICF
EGSVLLKVRNRDLVVCPRPCHFPLQHTPASDLR
AQELRGQCGVPGGGAVAGPQARCTPSQTWSFRFL
SSKCRFQLAVPPACSLLRCLGRGHIPHSSSPYS
ACLLFQAGGKLLFLTFQGEG*AEGDLCPCRPAP
WVGTGKGSDAPDTTPLATPDASAVLDSLFSVPPA
VMSLLSPARAGDRCFTEDLH*KHFLNCCTGRDV
SKTAS*S*VYFFAQGVMLMNSSFILIFVQPTGA
SFSNVFHSYPPPKNKRNICSLLSVFEFLAILYLD
TLKNVND*FGH*IL*HIRY*NDIKIKVI*IH

Frame 2

RNAGVWFRVVCGSG**GCCSAGRRRRAAGA*GL
TREAAAERAGRSAGPRGSRECRARGRGREAWGS
RALPSGTCPGADPARSVEAASGR*ARETI*RGE
NSLLRKLAHRKDGLLGQSNYHSSSYSTVTCDQ**
HGNV*DGSH*S*C*PREDSSSFNAWRQWVRNSG
KQW*DSGLCICPVSRYYLKLGLWY*KTLKHSSK
IRTTPKRETKPDQMQKYSVERKKF*AISPGVKVT
V*KKISQREASNFWEAVDIICTPRTVPSAAE*P
F*RVFQI*WQGSCRYNSNQEDRCLPPSALEPGQ
TAANDRGDNGQRQGAGPDRAHLLAVYKRRTGAEA
Q*QCQCLLPAYC*G*WGGGHRFPPAGFQ*AHS*
VWLQYFGPG*KVLISWSDIQRVTLCSNKCCSWI
LPYSGGQHKGYHEGNLTEGSEAKKRIPESFRPSV
PPGEAERAQCRR*PGQHFGEPERMGVLPGPREQ
FKGRRGF*GGFAN*HSHSTGYA*QPPLQVIQSQ
HDPQTAIHNRRTARYLWRQSRDRPCYESESQH*V
LD*AETHLNRFRPALCL*PC*REKPQSRNI*TH
VSKQSRL*TPLL*IGRCYRQ*NCAQG*LHPGIA
S*HCPG*LLCSKTKKTEQTYELQLPEGEEIRAAV
TLASSLNLFRSSEPACQGQVP*SPPGVLKSSGG
GQPLAHWHRAGGLSGKVSGAP*EGALGTLPWDG
SLLGSGFDKRCLGVRPPPRGATCRPATFNACHPA
RGCTEPCPHISLQLDQIS*SKQQKCTFLFFLLI
NRCTLYHGWYDGPFFGAED*LCYSL*NLFPY*T
GRLEKLWFDFSEEMFRS*SIVLTMPFV*MSAFAS
RVVSY*KLGTET*WCVQGRVTFPFSTPQLLTSE
PRSCVDSVGCQEEGRWLVLRHAALPARHGLSVS
*VASVGFSWQFHLHVLCFAALEGATFPIPLLLTA
PASFFKQAESCCFSRFRERGERRETCVRAVRLP
GWEQARDQMPLTPRLWPHQMPLQSSTASSVSLL
R*CPYCPQPGPGTGVSLRTCIRNIF*IVVQEEMC
LKQHLKAECISLHKGSC**ILLSF*SLFSQQER
PFLMSSIPTPHPKTKEIFVACYLYLNF*QFYI*
IL*KM*MTNLVIKSCDIFDIKMILK*KSYKYT

Sequence NM_001006621

TCCGGAACGCCGGGGTGTGGTTCCGGGTCGTGTGCGGCTCGGGGTAATAGGGCTGCTGCTCGGCCGGCCGGCGGCGGCGAGCAGCAGGGGCATGAGGGCT
AACCCGGGAAGCGGCAGCTGAGCGGGCCGGGAGGAGCGCCGGTCCCCGTGGATCCCGAGAGTGCAGAGCTCGGGGCAGGGGCCGGGAGGCGTGGGGGAGC
CGGGCCCTCCCCTCAGGAACGTGTCCCGGGGCCGACCCGGCCCGTAGTGTGGAAGCAGCTTCAGCCCAGGAGTTAAAGTCACTGTTTGAAAAAAAATCTC
TCAAAGAGAAGCCTCCAATTTCTGGGAAGCAGTCGATATTATCTGTACGCCTAGAACAGTGCCCTCTGCAGCTGAATAACCCTTTTAACGAGTATTCCAA
ATTTGATGGCAAGGGTCATGTAGGTACAACAGCAACCAAGAAGATCGATGTCTACCTCCCTCTGCACTCGAGCCAGGACAGACTGCTGCCAATGACCGTG
GTGACAATGGCCAGCGCCAGGGTGCAGGACCTGATCGGGCTCATCTGCTGGCAGTATACAAGCGAAGGACGGGAGCCGAAGCTCAATGACAATGTCAGTG
CCTACTGCCTGCATATTGCTGAGGATGATGGGGAGGTGGACACCGATTTCCCCCCGCTGGATTCCAATGAGCCCATTCATAAGTTTGGCTTCAGTACTTT
GGCCCTGGTTGAAAAGTACTCATCTCCTGGTCTGACATCCAAAGAGTCACTCTTTGTTCGAATAAATGCTGCTCATGGATTCTCCCTTATTCAGGTGGAC
AACACAAAGGTTACCATGAAGGAAATCTTACTGAAGGCAGTGAAGCGAAGAAAAGGATCCCAGAAAGTTTCAGGCCCTCAGTACCGCCTGGAGAAGCAGA
GCGAGCCCAATGTCGCCGTTGACCTGGACAGCACTTTGGAGAGCCAGAGCGCATGGGAGTTCTGCCTGGTCCGCGAGAACAGTTCAAGGGCAGACGGGGT
TTTTGAGGAGGATTCGCAAATTGACATAGCCACAGTACAGGATATGCTTAGCAGCCACCATTACAAGTCATTCAAAGTCAGCATGATCCACAGACTGCGA
TTCACAACCGACGTACAGCTAGGTATCTCTGGAGACAAAGTAGAGATAGACCCTGTTACGAATCAGAAAGCCAGCACTAAGTTTTGGATTAAGCAGAAAC
CCATCTCAATCGATTCCGACCTGCTCTGTGCCTGTGACCTTGCTGAAGAGAAAAGCCCCAGTCACGCAATATTTAAACTCACGTATCTAAGCAATCACGA
CTATAAACACCTCTACTTTGAATCGGACGCTGCTACCGTCAATGAAATTGTGCTCAAGGTTAACTACATCCTGGAATCGCGAGCTAGCACTGCCCGGGCT
GACTACTTTGCTCAAAAACAAAGAAAACTGAACAGACGTACGAGCTTCAGCTTCCAGAAGGAGAAGAAATCCGGGCAGCAGTGACACTGGCCTCCAGCCT
CAATCTGTTCCGTAGCTCAGAGCCTGCCTGCCAGGGCCAAGTGCCCTAGAGTCCACCCGGTGTCCTGAAGTCCTCGGGGGGAGGCCAGCCCCTGGCTCAC
TGGCACAGGGCAGGTGGGCTCTCGGGGAAGGTGTCGGGGGCCCCCTAGGAGGGAGCGCTGGGGACATTGCCATGGGACGGAAGTCTGCTTGGCAGTGGCT
TTGATAAGCGATGCTTGGGGGTCAGACCACCCCCTAGAGGAGCCACGTGCCGCCCAGCCACCTTCAATGCCTGCCACCCTGCCCGAGGATGTACAGAGCC
GTGCCCACACATTTCCTTGCAACTTGATCAAATTTCTTAAAGCAAACAACAAAAATGTACATTTCTGTTTTTCCTTTTAATAAACAGGTGTACTCTTTAT
CATGGTTGGTATGATGGACCATTCTTTGGGGCGGAGGATTGATTATGTTACTCTCTTTAAAATCTGTTCCCATATTGAACAGGCAGATTGGAAAAGCTAT
GGTTCGATTTCTCAGAAGAAATGTTTAGGTCTTAGTCAATAGTTTTAACTATGCCATTTGTTTAAATGAGTGCATTTGCTTCGAGGGTAGTGTCTTACTA
AAAGTTAGGAACAGAGACCTAGTGGTGTGTCCAAGGCCGTGTCACTTTCCCCTTCAGCACACCCCAGCTTCTGACCTCAGAGCCCAGGAGCTGCGTGGAC
AGTGTGGGGTGCCAGGAGGAGGGGCGGTGGCTGGTCCTCAGGCACGCTGCACTCCCAGCCAGACATGGTCTTTCCGTTTCTTAAGTAGCAAGTGTAGGTT
TCAGCTGGCAGTTCCACCTGCATGTTCTCTGCTTCGCTGCCTTGGAAGGGGCCACATTCCCCATTCCTCTTCTCCTTACAGCGCCTGCCTCCTTTTTCAA
GCAGGCGGAAAGCTGCTGTTTCTCACGTTTCAGGGAGAGGGGTGAGCGGAGGGAGACCTGTGTCCGTGCCGTCCGGCTCCCTGGGTGGGAACAGGCAAGG
GATCAGATGCCCCTGACACCACGCCTCTGGCCACACCAGATGCCTCTGCAGTCCTCGACAGCCTCTTCAGTGTCCCTCCTGCGGTGATGTCCTTACTGTC
CCCAGCCAGGGCCGGGGACCGGTGTTTCACTGAGGACCTGCATTAGAAACATTTTTTAAATTGTTGTACAGGAAGAGATGTGTCTAAAACAGCATCTTAA
AGCTGAGTGTATTTCTTTGCACAAGGGGTCATGCTGATGAATTCTTCTTTCATTCTGATCTTTGTTCAGCCAACAGGAGCGTCCTTTTCTAATGTCTTCC
ATTCCTACCCCCCACCCAAAAACAAAAGAAATATTTGTAGCTTGCTATCTGTATTTGAATTTTTAGCAATTTTATATTTAGATACTTTGAAAAATGTAAA
TGACTAATTTGGTCATTAAATCTTGTGACATATTCGATATTAAAATGATATTAAAATAAAAGTCATATAAATACACA
  • refseq_MAPKAP1.F3 (forward primer)
  • refseq_MAPKAP1.R3 (reverse primer)
  • Single exon skipping

Frame 0

SGTPGCGSGSCAARGNRAAARPAGGGEQQGHEG
*PGKRQLSGPGGAPVPVDPESAELGAGAGRRGGA
GPSPQERVPGPTRPVVWKQLQPRS*SHCLKKNL
SKRSLQFLGSSRYYLYA*NSALCS*ITLLTSIP
NLMARVM*VQQQPRRSMSTSLCTRARTDCCQ*PW
*QWPAPGCRT*SGSSAGSIQAKDGSRSSMTMSV
PTACILLRMMGRWTPISPRWIPMSPFISLASVL
WPWLKSTHLLV*HPKSHSLFE*MLLMDSPLFRWT
TQRLP*RKSY*RQ*SEEKDPRKFQALSTAWRSR
ASPMSPLTWTALWRARAHGSSAWSARTVQGQTG
FLRRIRKLT*PQYRICLAATITSHSKSA*STDCD
SQPTYS*VSLETK*R*TLLRIRKPALSFGLSRN
PSQSIPTCSVPVTLLKRKAPVTQYLNSRI*AIT
TINTSTLNRTLLPSMKLCSRLTTSWNRELALPGL
TTLLKNKEN*TDVRASASRRRRNPGSSDTGLQP
QSVP*LRACLPGPSALESTRCPEVLGGRPAPGS
LAQGRWALGEGVGGPLGGSAGDIAMGRKSAWQWL
**AMLGGQTTP*RSHVPPSHLQCLPPCPRMYRA
VPTHFLAT*SNFLKQTTKMYISVFPFNKQVYSL
SWLV*WTILWGGGLIMLLSLKSVPILNRQIGKAM
VRFLRRNV*VLVNSFNYAICLNECICFEGSVLL
KVRNRDLVVCPRPCHFPLQHTPASDLRAQELRG
QCGVPGGGAVAGPQARCTPSQTWSFRFLSSKCRF
QLAVPPACSLLRCLGRGHIPHSSSPYSACLLFQ
AGGKLLFLTFQGEG*AEGDLCPCRPAPWVGTGK
GSDAPDTTPLATPDASAVLDSLFSVPPAVMSLLS
PARAGDRCFTEDLH*KHFLNCCTGRDVSKTAS*
S*VYFFAQGVMLMNSSFILIFVQPTGASFSNVF
HSYPPPKNKRNICSLLSVFEFLAILYLDTLKNVN
D*FGH*IL*HIRY*NDIKIKVI*IH

Frame 1

PERRGVVPGRVRLGVIGLLLGRPAAASSRGMRA
NPGSGS*AGREERRSPWIPRVQSSGQGPGGVGE
PGPPLRNVSRGRPGP*CGSSFSPGVKVTV*KKIS
QREASNFWEAVDIICTPRTVPSAAE*PF*RVFQ
I*WQGSCRYNSNQEDRCLPPSALEPGQTAANDR
GDNGQRQGAGPDRAHLLAVYKRRTGAEAQ*QCQC
LLPAYC*G*WGGGHRFPPAGFQ*AHS*VWLQYF
GPG*KVLISWSDIQRVTLCSNKCCSWILPYSGG
QHKGYHEGNLTEGSEAKKRIPESFRPSVPPGEAE
RAQCRR*PGQHFGEPERMGVLPGPREQFKGRRG
F*GGFAN*HSHSTGYA*QPPLQVIQSQHDPQTA
IHNRRTARYLWRQSRDRPCYESESQH*VLD*AET
HLNRFRPALCL*PC*REKPQSRNI*THVSKQSR
L*TPLL*IGRCYRQ*NCAQG*LHPGIAS*HCPG
*LLCSKTKKTEQTYELQLPEGEEIRAAVTLASSL
NLFRSSEPACQGQVP*SPPGVLKSSGGGQPLAH
WHRAGGLSGKVSGAP*EGALGTLPWDGSLLGSG
FDKRCLGVRPPPRGATCRPATFNACHPARGCTEP
CPHISLQLDQIS*SKQQKCTFLFFLLINRCTLY
HGWYDGPFFGAED*LCYSL*NLFPY*TGRLEKL
WFDFSEEMFRS*SIVLTMPFV*MSAFASRVVSY*
KLGTET*WCVQGRVTFPFSTPQLLTSEPRSCVD
SVGCQEEGRWLVLRHAALPARHGLSVS*VASVG
FSWQFHLHVLCFAALEGATFPIPLLLTAPASFFK
QAESCCFSRFRERGERRETCVRAVRLPGWEQAR
DQMPLTPRLWPHQMPLQSSTASSVSLLR*CPYC
PQPGPGTGVSLRTCIRNIF*IVVQEEMCLKQHLK
AECISLHKGSC**ILLSF*SLFSQQERPFLMSS
IPTPHPKTKEIFVACYLYLNF*QFYI*IL*KM*
MTNLVIKSCDIFDIKMILK*KSYKYT

Frame 2

RNAGVWFRVVCGSG**GCCSAGRRRRAAGA*GL
TREAAAERAGRSAGPRGSRECRARGRGREAWGS
RALPSGTCPGADPARSVEAASAQELKSLFEKKS
LKEKPPISGKQSILSVRLEQCPLQLNNPFNEYSK
FDGKGHVGTTATKKIDVYLPLHSSQDRLLPMTV
VTMASARVQDLIGLICWQYTSEGREPKLNDNVS
AYCLHIAEDDGEVDTDFPPLDSNEPIHKFGFSTL
ALVEKYSSPGLTSKESLFVRINAAHGFSLIQVD
NTKVTMKEILLKAVKRRKGSQKVSGPQYRLEKQ
SEPNVAVDLDSTLESQSAWEFCLVRENSSRADGV
FEEDSQIDIATVQDMLSSHHYKSFKVSMIHRLR
FTTDVQLGISGDKVEIDPVTNQKASTKFWIKQK
PISIDSDLLCACDLAEEKSPSHAIFKLTYLSNHD
YKHLYFESDAATVNEIVLKVNYILESRASTARA
DYFAQKQRKLNRRTSFSFQKEKKSGQQ*HWPPA
SICSVAQSLPARAKCPRVHPVS*SPRGEASPWLT
GTGQVGSRGRCRGPPRRERWGHCHGTEVCLAVA
LISDAWGSDHPLEEPRAAQPPSMPATLPEDVQS
RAHTFPCNLIKFLKANNKNVHFCFSF**TGVLFI
MVGMMDHSLGRRIDYVTLFKICSHIEQADWKSY
GSISQKKCLGLSQ*F*LCHLFK*VHLLRG*CLT
KS*EQRPSGVSKAVSLSPSAHPSF*PQSPGAAWT
VWGARRRGGGWSSGTLHSQPDMVFPFLK*QV*V
SAGSSTCMFSASLPWKGPHSPFLFSLQRLPPFS
SRRKAAVSHVSGRGVSGGRPVSVPSGSLGGNRQG
IRCP*HHASGHTRCLCSPRQPLQCPSCGDVLTV
PSQGRGPVFH*GPALETFFKLLYRKRCV*NSIL
KLSVFLCTRGHADEFFFHSDLCSANRSVLF*CLP
FLPPTQKQKKYL*LAICI*IFSNFIFRYFEKCK
*LIWSLNLVTYSILK*Y*NKSHINT

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