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Sequences

Sequence NM_206861

GCCTGCTCCAAGGGAAGGATCAGGAGAGAAGAAACGCAAATCCCAGAACCGTGCCAACATATAAAACCCCACATTAAGGGTTGTACAGTGCACTGGGATT
TCTCAAGTCACCCGCTTGGTCCTCTTCCAAGTATACTTTACTTCCTTTCATTCCTCTCTAAAACTTTTTTAAAAACTTTCACTCCTGCTCTAAAAGTTAT
CTTGGTTTCTTACTCTACCTTATGCCCCTTGGGCGAATTTTTTCCTCTGAGGAGGGAAGAATAGAGTTGCTGCTGCAGACACATCAGATTCCCTACTGGT
AACAGCTGGAGTGCGTCACCTCTGACAAAATTCTGGGGACGCTGGGAACACTGAATCAACATGGGCAATGAGAACAGCACCTCGGACAACCAGAGGACTT
TATCAGCTCAGACTCCAAGGTCCGCGCAGCCACCCGGGAACAGTCAGAATATAAAAAGGAAGCAGCAGGACACGCCCGGAAGCCCTGACCACAGAGACGC
GTCCAGTTCACCTGTGGCAGATGATATCATCCAGCCCGCTGCCCCCGCAGACCTGGAAAGCCCAACCTTAGCTGCCTCTTCCTACCACGGTGATGTTGTT
GGCCAGGTCTCTACGGATCTGATAGCCCAGAGGAGTTCCGATTCTGAAGAGGCATTTGAGACCCCGGAGTCAACGACCCCTGTCAAAGCTCCGCCAGCTC
CACCCCCACCACCCCCCGAAGTCATCCCAGAACCCGAGGTCAGCACACAGCCACCCCCGGAAGAACCAGGATGTGGTTCTGAGACAGTCCCTGTCCCTGA
TGGCCCACGGAGCGACTCGGTGGAAGGAAGTCCCTTCCGTCCCCCGTCACACTCCTTCTCTGCCGTCTTCGATGAAGACAAGCCGATAGCCAGCAGTGGG
ACTTACAACTTGGACTTTGACAACATTGAGCTTGTGGATACCTTTCAGACCTTGGAGCCTCGTGCCTCAGACGCTAAGAATCAGGAGGGCAAAGTGAACA
CACGGAGGAAGTCCACGGATTCCGTCCCCATCTCTAAGTCTACACTGTCCCGGTCGCTCAGCCTGCAAGCCAGTGACTTTGATGGTGCTTCTTCCTCAGG
CAATCCCGAGGCCGTGGCCCTTGCCCCAGATGCATATAGCACGGGTTCCAGCAGTGCTTCTAGTACCCTTAAGCGAACTAAAAAACCGAGGCCGCCTTCC
TTAAAAAAGAAACAGACCACCAAGAAACCCACAGAGACCCCCCCAGTGAAGGAGACGCAACAGGAGCCAGATGAAGAGAGCCTTGTCCCCAGTGGGGAGA
ATCTAGCATCTGAGACGAAAACGGAATCTGCCAAGACGGAAGGTCCTAGCCCAGCCTTATTGGAGGAGACGCCCCTTGAGCCCGCTGTGGGGCCCAAAGC
TGCCTGCCCTCTGGACTCAGAGAGTGCAGAAGGGGTTGTCCCCCCGGCTTCTGGAGGTGGCAGAGTGCAGAACTCACCCCCTGTCGGGAGGAAAACGCTG
CCTCTTACCACGGCCCCGGAGGCAGGGGAGGTAACCCCATCGGATAGCGGGGGGCAAGAGGACTCTCCAGCCAAAGGGCTCTCCGTAAGGCTGGAGTTTG
ACTATTCTGAGGACAAGAGTAGTTGGGACAACCAGCAGGAAAACCCCCCTCCTACCAAAAAGATAGGCAAAAAGCCAGTTGCCAAAATGCCCCTGAGGAG
GCCAAAGATGAAAAAGACACCCGAGAAACTTGACAACACTCCTGCCTCACCTCCCAGATCCCCTGCTGAACCCAATGACATCCCCATTGCTAAAGGTACT
TACACCTTTGATATTGACAAGTGGGATGACCCCAATTTTAACCCTTTTTCTTCCACCTCAAAAATGCAGGAGTCTCCCAAACTGCCCCAACAATCATACA
ACTTTGACCCAGACACCTGTGATGAGTCCGTTGACCCCTTTAAGACATCCTCTAAGACCCCCAGCTCACCTTCTAAATCCCCAGCCTCCTTTGAGATCCC
AGCCAGTGCTATGGAAGCCAATGGAGTGGACGGGGATGGGCTAAACAAGCCCGCCAAGAAGAAGAAGACGCCCCTAAAGACTGACACATTTAGGGTGAAA
AAGTCGCCAAAACGGTCTCCTCTCTCTGATCCACCTTCCCAGGACCCCACCCCAGCTGCTACACCAGAAACACCACCAGTGATCTCTGCGGTGGTCCACG
CCACAGATGAGGAAAAGCTGGCGGTCACCAACCAGAAGTGGACGTGCATGACAGTGGACCTAGAGGCTGACAAACAGGACTACCCGCAGCCCTCGGACCT
GTCCACCTTTGTAAACGAGACCAAATTCAGTTCACCCACTGAGGAGTTGGATTACAGAAACTCCTATGAAATTGAATATATGGAGAAAATTGGCTCCTCC
TTACCTCAGGACGACGATGCCCCGAAGAAGCAGGCCTTGTACCTTATGTTTGACACTTCTCAGGAGAGCCCTGTCAAGTCATCTCCCGTCCGCATGTCAG
AGTCCCCGACGCCGTGTTCAGGGTCAAGTTTTGAAGAGACTGAAGCCCTTGTGAACACTGCTGCGAAAAACCAGCATCCTGTCCCACGAGGACTGGCCCC
TAACCAAGAGTCACACTTGCAGGTGCCAGAGAAATCCTCCCAGAAGGAGCTGGAGGCCATGGGCTTGGGCACCCCTTCAGAAGCGATTGAAATTACAGCT
CCCGAGGGCTCCTTTGCCTCTGCTGACGCCCTCCTCAGCAGGCTAGCTCACCCCGTCTCTCTCTGTGGTGCACTTGACTATCTGGAGCCCGACTTAGCAG
AAAAGAACCCCCCACTATTCGCTCAGAAACTCCAGGAGGAGTTAGAGTTTGCCATCATGCGGATAGAAGCCCTGAAGCTGGCCAGGCAGATTGCTTTGGC
TTCCCGCAGCCACCAGGATGCCAAGAGAGAGGCTGCTCACCCAACAGACGTCTCCATCTCCAAAACAGCCTTGTACTCCCGCATCGGGACCGCTGAGGTG
GAGAAACCTGCAGGCCTTCTGTTCCAGCAGCCCGACCTGGACTCTGCCCTCCAGATCGCCAGAGCAGAGATCATAACCAAGGAGAGAGAGGTCTCAGAAT
GGAAAGATAAATATGAAGAAAGCAGGCGGGAAGTGATGGAAATGAGGAAAATAGTGGCCGAGTATGAGAAGACCATCGCTCAGATGATAGAGGACGAACA
GAGAGAGAAGTCAGTCTCCCACCAGACGGTGCAGCAGCTGGTTCTGGAGAAGGAGCAAGCCCTGGCCGACCTGAACTCCGTGGAGAAGTCTCTGGCCGAC
CTCTTCAGAAGATATGAGAAGATGAAGGAGGTCCTAGAAGGCTTCCGCAAGAATGAAGAGGTGTTGAAGAGATGTGCGCAGGAGTACCTGTCCCGGGTGA
AGAAGGAGGAGCAGAGGTACCAGGCCCTGAAGGTGCACGCGGAGGAGAAACTGGACAGGGCCAATGCTGAGATTGCTCAGGTTCGAGGCAAGGCCCAGCA
GGAGCAAGCCGCCCACCAGGCCAGCCTGCGGAAGGAGCAGCTGCGAGTGGACGCCCTGGAAAGGACGCTGGAGCAGAAGAATAAAGAAATAGAAGAACTC
ACCAAGATTTGTGACGAACTGATTGCCAAAATGGGGAAAAGCTAACTCTGAACCGAATGTTTTGGACTTAACTGTTGCGTGCAATATGACCGTCGGCACA
CTGCTGTTCCTCCAGTTCCATGGACAGGTTCTGTTTTCACTTTTTCGTATGCACTACTGTATTTCCTTTCTAAATAAAATTGATTTGATTGTATGCAGTA
CTAAGGAGACTATCAGAATTTCTTGCTATTGGTTTGCATTTTCCTAGTATAATTCATAGCAAGTTGACCTCAGAGTTCCTGTATCAGGGAGATTGTCTGA
TTCTCTAATAAAAGACACATTGCTGACCTTGGCCTTGCCCTTTGTACACAAGTTCCCAGGGTGAGCAGCTTTTGGATTTAATATGAACATGTACAGCGTG
CATAGGGACTCTTGCCTTAAGGAGTGTAAACTTGATCTGCATTTGCTGATTTGTTTTTAAAAAAACAAGAAATGCATGTTTCAAATAAAATTCTCTATTG
TAAATAAAATTTTTTCTTTGGATCTTGGCAA
  • refseq_TACC2.F4 (forward primer)
  • refseq_TACC2.R4 (reverse primer)
  • Single exon skipping

Frame 0

ACSKGRIRREETQIPEPCQHIKPHIKGCTVHWD
FSSHPLGPLPSILYFLSFLSKTFLKTFTPALKVI
LVSYSTLCPLGEFFPLRREE*SCCCRHIRFPTG
NSWSASPLTKFWGRWEH*INMGNENSTSDNQRT
LSAQTPRSAQPPGNSQNIKRKQQDTPGSPDHRDA
SSSPVADDIIQPAAPADLESPTLAASSYHGDVV
GQVSTDLIAQRSSDSEEAFETPESTTPVKAPPA
PPPPPPEVIPEPEVSTQPPPEEPGCGSETVPVPD
GPRSDSVEGSPFRPPSHSFSAVFDEDKPIASSG
TYNLDFDNIELVDTFQTLEPRASDAKNQEGKVN
TRRKSTDSVPISKSTLSRSLSLQASDFDGASSSG
NPEAVALAPDAYSTGSSSASSTLKRTKKPRPPS
LKKKQTTKKPTETPPVKETQQEPDEESLVPSGE
NLASETKTESAKTEGPSPALLEETPLEPAVGPKA
ACPLDSESAEGVVPPASGGGRVQNSPPVGRKTL
PLTTAPEAGEVTPSDSGGQEDSPAKGLSVRLEF
DYSEDKSSWDNQQENPPPTKKIGKKPVAKMPLRR
PKMKKTPEKLDNTPASPPRSPAEPNDIPIAKGT
YTFDIDKWDDPNFNPFSSTSKMQESPKLPQQSY
NFDPDTCDESVDPFKTSSKTPSSPSKSPASFEIP
ASAMEANGVDGDGLNKPAKKKKTPLKTDTFRVK
KSPKRSPLSDPPSQDPTPAATPETPPVISAVVH
ATDEEKLAVTNQKWTCMTVDLEADKQDYPQPSDL
STFVNETKFSSPTEELDYRNSYEIEYMEKIGSS
LPQDDDAPKKQALYLMFDTSQESPVKSSPVRMS
ESPTPCSGSSFEETEALVNTAAKNQHPVPRGLAP
NQESHLQVPEKSSQKELEAMGLGTPSEAIEITA
PEGSFASADALLSRLAHPVSLCGALDYLEPDLA
EKNPPLFAQKLQEELEFAIMRIEALKLARQIALA
SRSHQDAKREAAHPTDVSISKTALYSRIGTAEV
EKPAGLLFQQPDLDSALQIARAEIITKEREVSE
WKDKYEESRREVMEMRKIVAEYEKTIAQMIEDEQ
REKSVSHQTVQQLVLEKEQALADLNSVEKSLAD
LFRRYEKMKEVLEGFRKNEEVLKRCAQEYLSRV
KKEEQRYQALKVHAEEKLDRANAEIAQVRGKAQQ
EQAAHQASLRKEQLRVDALERTLEQKNKEIEEL
TKICDELIAKMGKS*L*TECFGLNCCVQYDRRH
TAVPPVPWTGSVFTFSYALLYFLSK*N*FDCMQY
*GDYQNFLLLVCIFLV*FIAS*PQSSCIREIV*
FSNKRHIADLGLALCTQVPRVSSFWI*YEHVQR
A*GLLP*GV*T*SAFADLFLKKQEMHVSNKILYC
K*NFFFGSWQ

Frame 1

PAPREGSGEKKRKSQNRANI*NPTLRVVQCTGI
SQVTRLVLFQVYFTSFHSSLKLF*KLSLLL*KL
SWFLTLPYAPWANFFL*GGKNRVAAADTSDSLLV
TAGVRHL*QNSGDAGNTESTWAMRTAPRTTRGL
YQLRLQGPRSHPGTVRI*KGSSRTRPEALTTET
RPVHLWQMISSSPLPPQTWKAQP*LPLPTTVMLL
ARSLRI**PRGVPILKRHLRPRSQRPLSKLRQL
HPHHPPKSSQNPRSAHSHPRKNQDVVLRQSLSL
MAHGATRWKEVPSVPRHTPSLPSSMKTSR*PAVG
LTTWTLTTLSLWIPFRPWSLVPQTLRIRRAK*T
HGGSPRIPSPSLSLHCPGRSACKPVTLMVLLPQ
AIPRPWPLPQMHIARVPAVLLVPLSELKNRGRLP
*KRNRPPRNPQRPPQ*RRRNRSQMKRALSPVGR
I*HLRRKRNLPRRKVLAQPYWRRRPLSPLWGPK
LPALWTQRVQKGLSPRLLEVAECRTHPLSGGKRC
LLPRPRRQGR*PHRIAGGKRTLQPKGSP*GWSL
TILRTRVVGTTSRKTPLLPKR*AKSQLPKCP*G
GQR*KRHPRNLTTLLPHLPDPLLNPMTSPLLKVL
TPLILTSGMTPILTLFLPPQKCRSLPNCPNNHT
TLTQTPVMSPLTPLRHPLRPPAHLLNPQPPLRS
QPVLWKPMEWTGMG*TSPPRRRRRP*RLTHLG*K
SRQNGLLSLIHLPRTPPQLLHQKHHQ*SLRWST
PQMRKSWRSPTRSGRA*QWT*RLTNRTTRSPRT
CPPL*TRPNSVHPLRSWITETPMKLNIWRKLAPP
YLRTTMPRRSRPCTLCLTLLRRALSSHLPSACQ
SPRRRVQGQVLKRLKPL*TLLRKTSILSHEDWP
LTKSHTCRCQRNPPRRSWRPWAWAPLQKRLKLQL
PRAPLPLLTPSSAG*LTPSLSVVHLTIWSPT*Q
KRTPHYSLRNSRRS*SLPSCG*KP*SWPGRLLW
LPAATRMPRERLLTQQTSPSPKQPCTPASGPLRW
RNLQAFCSSSPTWTLPSRSPEQRS*PRRERSQN
GKINMKKAGGK*WK*GK*WPSMRRPSLR**RTN
RERSQSPTRRCSSWFWRRSKPWPT*TPWRSLWPT
SSEDMRR*RRS*KASARMKRC*RDVRRSTCPG*
RRRSRGTRP*RCTRRRNWTGPMLRLLRFEARPS
RSKPPTRPACGRSSCEWTPWKGRWSRRIKK*KNS
PRFVTN*LPKWGKANSEPNVLDLTVACNMTVGT
LLFLQFHGQVLFSLFRMHYCISFLNKIDLIVCS
TKETIRISCYWFAFS*YNS*QVDLRVPVSGRLSD
SLIKDTLLTLALPFVHKFPG*AAFGFNMNMYSV
HRDSCLKECKLDLHLLICF*KNKKCMFQIKFSI
VNKIFSLDLG

Frame 2

LLQGKDQERRNANPRTVPTYKTPH*GLYSALGF
LKSPAWSSSKYTLLPFIPL*NFFKNFHSCSKSY
LGFLLYLMPLGRIFSSEEGRIELLLQTHQIPYW
*QLECVTSDKILGTLGTLNQHGQ*EQHLGQPEDF
ISSDSKVRAATREQSEYKKEAAGHARKP*PQRR
VQFTCGR*YHPARCPRRPGKPNLSCLFLPR*CC
WPGLYGSDSPEEFRF*RGI*DPGVNDPCQSSASS
TPTTPRSHPRTRGQHTATPGRTRMWF*DSPCP*
WPTERLGGRKSLPSPVTLLLCRLR*RQADSQQW
DLQLGL*QH*ACGYLSDLGASCLRR*ESGGQSEH
TEEVHGFRPHL*VYTVPVAQPASQ*L*WCFFLR
QSRGRGPCPRCI*HGFQQCF*YP*AN*KTEAAF
LKKETDHQETHRDPPSEGDATGAR*REPCPQWGE
SSI*DENGICQDGRS*PSLIGGDAP*ARCGAQS
CLPSGLRECRRGCPPGFWRWQSAELTPCREENA
ASYHGPGGRGGNPIG*RGARGLSSQRALRKAGV*
LF*GQE*LGQPAGKPPSYQKDRQKASCQNAPEE
AKDEKDTRET*QHSCLTSQIPC*TQ*HPHC*RY
LHL*Y*QVG*PQF*PFFFHLKNAGVSQTAPTIIQ
L*PRHL**VR*PL*DIL*DPQLTF*IPSLL*DP
SQCYGSQWSGRGWAKQARQEEEDAPKD*HI*GE
KVAKTVSSL*STFPGPHPSCYTRNTTSDLCGGPR
HR*GKAGGHQPEVDVHDSGPRG*QTGLPAALGP
VHLCKRDQIQFTH*GVGLQKLL*N*IYGENWLL
LTSGRRCPEEAGLVPYV*HFSGEPCQVISRPHVR
VPDAVFRVKF*RD*SPCEHCCEKPASCPTRTGP
*PRVTLAGAREILPEGAGGHGLGHPFRSD*NYS
SRGLLCLC*RPPQQASSPRLSLWCT*LSGARLSR
KEPPTIRSETPGGVRVCHHADRSPEAGQADCFG
FPQPPGCQERGCSPNRRLHLQNSLVLPHRDR*G
GETCRPSVPAARPGLCPPDRQSRDHNQGERGLRM
ER*I*RKQAGSDGNEENSGRV*EDHRSDDRGRT
EREVSLPPDGAAAGSGEGASPGRPELRGEVSGR
PLQKI*EDEGGPRRLPQE*RGVEEMCAGVPVPGE
EGGAEVPGPEGARGGETGQGQC*DCSGSRQGPA
GASRPPGQPAEGAAASGRPGKDAGAEE*RNRRT
HQDL*RTDCQNGEKLTLNRMFWT*LLRAI*PSAH
CCSSSSMDRFCFHFFVCTTVFPF*IKLI*LYAV
LRRLSEFLAIGLHFPSIIHSKLTSEFLYQGDCL
IL**KTHC*PWPCPLYTSSQGEQLLDLI*TCTAC
IGTLALRSVNLICIC*FVFKKTRNACFK*NSLL
*IKFFLWILA

Sequence NM_206862

GCCTGCTCCAAGGGAAGGATCAGGAGAGAAGAAACGCAAATCCCAGAACCGTGCCAACATATAAAACCCCACATTAAGGGTTGTACAGTGCACTGGGATT
TCTCAAGTCACCCGCTTGGTCCTCTTCCAAGTATACTTTACTTCCTTTCATTCCTCTCTAAAACTTTTTTAAAAACTTTCACTCCTGCTCTAAAAGTTAT
CTTGGTTTCTTACTCTACCTTATGCCCCTTGGGCGAATTTTTTCCTCTGAGGAGGGAAGAATAGAGTTGCTGCTGCAGACACATCAGATTCCCTACTGGT
AACAGCTGGAGTGCGTCACCTCTGACAAAATTCTGGGGACGCTGGGAACACTGAATCAACATGGGCAATGAGAACAGCACCTCGGACAACCAGAGGACTT
TATCAGCTCAGACTCCAAGGTCCGCGCAGCCACCCGGGAACAGTCAGAATATAAAAAGGAAGCAGCAGGACACGCCCGGAAGCCCTGACCACAGAGACGC
GTCCAGCATTGGCAGCGTTGGGCTTGGAGGCTTCTGCACCGCTTCTGAGAGTTCTGCCAGCCTGGATCCATGCCTTGTGTCCCCAGAGGTGACTGAGCCA
AGGAAGGACCCACAGGGAGCCAGGGGGCCAGAAGGTTCTTTGCTGCCCAGCCCACCACCGTCCCAGGAGCGAGAGCACCCCTCGTCCTCCATGCCCTTTG
CCGAGTGTCCCCCGGAAGGTTGCTTGGCAAGTCCAGCAGCGGCACCTGAAGATGGTCCTCAGACTCAGTCTCCCAGGAGGGAACCTGCCCCAAATGCCCC
AGGAGACATCGCGGCGGCATTTCCCGCTGAGAGGGACAGCTCTACTCCATACCAAGAGATTGCTGCCGTCCCCAGTGCTGGAAGAGAGAGACAGCCGAAG
GAAGAAGGACAGAAGTCCTCCTTCTCCTTCTCCAGTGGCATCGACCAGTCACCTGGAATGTCGCCAGTACCCCTCAGAGAGCCAATGAAGGCACCGCTGT
GTGGAGAGGGGGACCAGCCTGGTGGTTTTGAGTCCCAAGAGAAAGAGGCTGCAGGTGGCTTTCCCCCTGCAGAGTCCAGGCAGGGGGTGGCTTCTGTGCA
AGTGACCCCTGAGGCCCCTGCTGCAGCCCAGCAGGGCACAGAAAGCTCAGCGGTCTTGGAGAAGTCCCCCCTAAAACCCATGGCCCCGATCCCACAAGAT
CCAGCCCCAAGAGCCTCAGACAGAGAAAGAGGCCAAGGGGAGGCGCCGCCTCAGTATTTAACAGATGACTTGGAATTCCTCAGGGCCTGCCATCTCCCTA
GGAGCAATTCAGGGGCTGCCCCAGAAGCAGAAGTGAATGCCGCTTCCCAGGAGAGCTGCCAGCAGCCAGTGGGAGCATATCTGCCGCACGCAGAGCTGCC
CTGGGGCTTGCCAAGTCCTGCCCTGGTGCCAGAGGCTGGGGGCTCTGGGAAGGAGGCTCTGGACACCATTGATGTTCAGGGTCACCCACAGACAGGGATG
CGAGGAACCAAGCCCAATCAAGTTGTCTGTGTGGCAGCAGGCGGCCAGCCCGAAGGGGGTTTGCCTGTGAGCCCTGAACCTTCCCTGCTCACTCCGACTG
AGGAAGCACATCCAGCTTCAAGCCTCGCTTCATTCCCAGCTGCTCAGATTCCTATTGCTGTAGAAGAACCTGGATCATCATCCAGGGAATCAGTTTCCAA
GGCTGGGATGCCAGTTTCTGCAGATGCAGCCAAAGAGGTGGTGGATGCAGGGTTGGTGGGACTGGAGAGGCAGGTGTCAGATCTTGGAAGCAAGGGAGAG
CATCCAGAAGGGGACCCTGGAGAGGTTCCTGCCCCATCACCCCAGGAGAGGGGAGAGCACTTGAACACGGAGCAAAGCCATGAGGTCCAACCAGGAGTAC
CACCCCCTCCTCTTCCCAAGGAGCAAAGCCATGAGGTCCAACCAGGAGCACCACCCCCTCCTCTTCCCAAGGCACCAAGTGAAAGTGCCAGAGGGCCACC
GGGGCCAACGGATGGAGCCAAGGTCCATGAAGATTCCACAAGCCCAGCCGTGGCTAAAGAAGGAAGCAGATCACCTGGTGACAGCCCTGGAGGAAAGGAG
GAAGCCCCAGAGCCACCTGATGGTGGAGACCCAGGGAACCTGCAAGGAGAGGACTCTCAGGCTTTCAGCAGCAAGCGTGATCCAGAAGTAGGCAAAGATG
AGCTTTCAAAGCCAAGCAGTGATGCAGAGAGCAGAGACCATCCCAGCTCACACTCAGCACAGCCACCCAGAAAGGGGGGTGCTGGGCACACGGACGGGCC
CCACTCTCAGACAGCAGAGGCTGATGCATCTGGCCTACCACACAAGCTGGGTGAGGAGGACCCCGTCCTGCCCCCTGTGCCAGATGGAGCTGGTGAGCCC
ACTGTTCCCGAAGGAGCCATCTGGGAGGGGTCAGGATTGCAGCCCAAATGTCCTGACACCCTTCAGAGCAGGGAAGGATTGGGAAGAATGGAGTCTTTCC
TGACTTTAGAATCAGAGAAATCAGATTTTCCACCAACTCCTGTTGCAGAGGTTGCACCCAAAGCCCAGGAAGGTGAGAGCACATTGGAAATAAGGAAGAT
GGGCAGCTGTGATGGGGAGGGCTTGCTGACGTCCCCAGATCAACCCCGCGGGCCGGCGTGTGATGCGTCGAGACAGGAATTTCATGCTGGGGTGCCACAT
CCCCCCCAGGGGGAGAACTTGGCAGCAGACCTGGGGCTCACGGCACTCATCCTGGACCAAGATCAGCAGGGAATCCCATCCTGCCCAGGGGAAGGCTGGA
TAAGAGGAGCTGCATCCGAGTGGCCCCTACTATCTTCTGAGAAGCATCTCCAGCCATCCCAGGCACAACCAGAGACATCCATCTTTGACGTGCTCAAGGA
GCAGGCCCAGCCACCTGAAAATGGGAAAGAGACTTCTCCAAGCCATCCAGGTTTTAAGGACCAGGGAGCAGATTCTTCCCAAATCCATGTACCTGTGGAA
CCTCAGGAAGATAACAACTTGCCCACTCATGGAGGACAGGAGCAGGCTTTGGGATCAGAACTTCAAAGTCAGCTCCCCAAAGGCACCCTGTCTGATACTC
CAACTTCATCTCCCACTGACATGGTTTGGGAGAGTTCTCTGACAGAAGAGTCAGAATTGTCAGCACCAACGAGACAGAAGTTGCCTGCACTAGGGGAGAA
GCGGCCAGAGGGAGCATGCGGTGATGGTCAGTCCTCGAGGGTCTCGCCTCCAGCAGCAGATGTCTTAAAAGACTTTTCTCTTGCAGGGAACTTCAGCAGA
AAGGAAACTTGCTGCACTGGGCAGGGGCCAAACAAGTCTCAACAGGCATTGGCTGATGCCTTGGAAGAAGGCAGCCAGCATGAAGAAGCATGTCAAAGGC
ATCCAGGAGCTTCTGAAGCAGCTGATGGTTGTTCCCCACTCTGGGGCTTGAGTAAGAGGGAGATGGCAAGTGGAAACACAGGGGAGGCCCCACCTTGTCA
GCCTGACTCAGTAGCTCTCCTGGATGCAGTTCCCTGCCTGCCAGCCCTGGCGCCCGCCAGCCCCGGAGTCACACCCACCCAGGATGCCCCAGAGACAGAG
GCATGTGATGAAACCCAGGAAGGCAGGCAGCAACCAGTGCCGGCCCCGCAGCAGAAAATGGAGTGCTGGGCCACTTCGGATGCAGAGTCCCCAAAGCTTC
TTGCAAGTTTCCCATCAGCTGGGGAGCAAGGTGGTGAAGCCGGGGCTGCTGAGACTGGTGGCAGCGCTGGTGCAGGAGACCCAGGAAAGCAGCAGGCTCC
GGAGAAACCTGGAGAAGCTACTTTGAGTTGTGGCCTCCTTCAGACTGAGCACTGCCTTACCTCCGGGGAGGAAGCTTCTACCTCTGCCCTACGTGAGTCC
TGCCAAGCTGAGCACCCCATGGCCAGCTGCCAGGATGCCTTGCTGCCAGCCAGAGAGCTGGGTGGGATTCCCAGGAGCACCATGGATTTTTCTACACACC
AGGCTGTCCCAGACCCAAAGGAGCTCCTGCTGTCTGGGCCACCAGAAGTGGCTGCTCCTGACACCCCTTACCTGCATGTCGACAGTGCTGCCCAGAGAGG
AGCAGAAGACAGTGGAGTGAAAGCTGTTTCCTCTGCAGACCCCAGAGCTCCTGGCGAAAGCCCCTGTCCTGTAGGGGAGCCCCCACTTGCCTTGGAAAAT
GCTGCCTCCTTGAAGCTGTTTGCTGGCTCCCTCGCCCCCCTGTTGCAACCAGGAGCTGCAGGTGGGGAAATCCCTGCAGTGCAAGCCAGCAGTGGTAGTC
CCAAAGCCAGAACCACTGAGGGACCAGTGGACTCCATGCCATGCCTGGACCGGATGCCACTTCTGGCCAAGGGCAAGCAGGCAACAGGGGAAGAGAAAGC
AGCAACAGCTCCAGGTGCAGGTGCCAAGGCCAGTGGGGAGGGCATGGCAGGTGATGCAGCAGGAGAGACAGAGGGCAGCATGGAGAGGATGGGAGAGCCT
TCCCAGGACCCAAAGCAGGGCACATCAGGTGGTGTGGACACAAGCTCTGAGCAAATCGCCACCCTCACTGGCTTCCCAGACTTCAGGGAGCACATCGCCA
AGATCTTCGAGAAGCCTGTGCTCGGAGCCCTGGCCACACCTGGAGAAAAGGCAGGAGCTGGGAGGAGTGCAGTGGGTAAAGACCTCACCAGGCCATTGGG
CCCAGAGAAGCTTCTAGATGGGCCTCCAGGAGTGGATGTCACCCTTCTCCCTGCACCTCCTGCTCGACTCCAGGTGGAGAAGAAGCAACAGTTGGCTGGA
GAGGCTGAGATTTCCCATCTGGCTCTGCAAGATCCAGCTTCAGACAAGCTTCTGGGTCCAGCAGGGCTGACCTGGGAGCGGAACTTGCCAGGTGCCGGTG
TGGGGAAGGAGATGGCAGGTGTCCCACCCACACTGAGGGAAGACGAGAGGCCAGAGGGGCCTGGGGCAGCCTGGCCAGGCCTGGAAGGCCAGGCTTACTC
ACAGCTGGAGAGGAGCAGGCAGGAATTAGCTTCAGGTCTTCCTTCACCAGCAGCTACTCAGGAGCTCCCTGTGGAGAGAGCTGCTGCCTTCCAGGTGGCT
CCCCATAGCCATGGAGAAGAGGCCGTGGCCCAAGACAGAATTCCTTCTGGAAAGCAGCACCAGGAAACATCTGCCTGCGACAGTCCACATGGAGAAGATG
GTCCCGGGGACTTTGCTCACACAGGGGTTCCAGGACATGTGCCAAGGTCCACGTGTGCCCCTTCTCCTCAGAGGGAGGTTTTGACTGTGCCTGAGGCCAA
CAGTGAGCCCTGGACCCTTGACACGCTTGGGGGTGAAAGGAGACCCGGAGTCACTGCTGGCATCTTGGAAATGCGAAATGCCCTGGGCAACCAGAGCACC
CCTGCACCACCAACTGGAGAAGTGGCAGACACTCCCCTGGAGCCTGGCAAGGTGGCAGGCGCTGCTGGGGAAGCAGAGGGTGACATCACCCTGAGCACAG
CTGAGACACAGGCATGTGCGTCCGGTGATCTGCCTGAAGCAGGTACTACGAGGACATTCTCCGTTGTGGCAGGTGACTTGGTGCTGCCAGGAAGCTGTCA
GGACCCAGCCTGCTCTGACAAGGCTCCGGGGATGGAGGGTACAGCTGCCCTTCATGGGGACAGCCCAGCCAGGCCCCAGCAGGCTAAGGAGCAGCCAGGG
CCTGAGCGCCCCATTCCAGCTGGGGATGGGAAGGTGTGCGTCTCCTCACCTCCAGAGCCTGACGAAACTCACGACCCGAAGCTGCAACATTTGGCTCCAG
AAGAGCTCCACACTGACAGAGAGAGCCCCAGGCCTGGCCCATCCATGTTACCTTCGGTTCCTAAGAAGGATGCTCCAAGAGTCATGGATAAAGTCACTTC
AGATGAGACCAGAGGTGCGGAAGGAACAGAAAGTTCACCTGTGGCAGATGATATCATCCAGCCCGCTGCCCCCGCAGACCTGGAAAGCCCAACCTTAGCT
GCCTCTTCCTACC
ACGGTGATGTTGTTGGCCAGGTCTCTACGGATCTGATAGCCCAGAGCATCTCCCCAGCTGCTGCCCATGCGGGTCTTCCTCCCTCGG
CTGCAGAACACATAGTTTCGCCATCTGCCCCAGCTGGTGACAGAGTAGAAGCTTCCACTCCCTCCTGCCCAGATCCGGCCAAGGACCTCAGCAG
GAGTTC
CGATTCTGAAGAGGCATTTGAGACCCCGGAGTCAACGACCCCTGTCAAAGCTCCGCCAGCTCCACCCCCACCACCCCCCGAAGTCATCCCAGAACCCGAG
GTCAGCACACAGCCACCCCCGGAAGAACCAGGATGTGGTTCTGAGACAGTCCCTGTCCCTGATGGCCCACGGAGCGACTCGGTGGAAGGAAGTCCCTTCC
GTCCCCCGTCACACTCCTTCTCTGCCGTCTTCGATGAAGACAAGCCGATAGCCAGCAGTGGGACTTACAACTTGGACTTTGACAACATTGAGCTTGTGGA
TACCTTTCAGACCTTGGAGCCTCGTGCCTCAGACGCTAAGAATCAGGAGGGCAAAGTGAACACACGGAGGAAGTCCACGGATTCCGTCCCCATCTCTAAG
TCTACACTGTCCCGGTCGCTCAGCCTGCAAGCCAGTGACTTTGATGGTGCTTCTTCCTCAGGCAATCCCGAGGCCGTGGCCCTTGCCCCAGATGCATATA
GCACGGGTTCCAGCAGTGCTTCTAGTACCCTTAAGCGAACTAAAAAACCGAGGCCGCCTTCCTTAAAAAAGAAACAGACCACCAAGAAACCCACAGAGAC
CCCCCCAGTGAAGGAGACGCAACAGGAGCCAGATGAAGAGAGCCTTGTCCCCAGTGGGGAGAATCTAGCATCTGAGACGAAAACGGAATCTGCCAAGACG
GAAGGTCCTAGCCCAGCCTTATTGGAGGAGACGCCCCTTGAGCCCGCTGTGGGGCCCAAAGCTGCCTGCCCTCTGGACTCAGAGAGTGCAGAAGGGGTTG
TCCCCCCGGCTTCTGGAGGTGGCAGAGTGCAGAACTCACCCCCTGTCGGGAGGAAAACGCTGCCTCTTACCACGGCCCCGGAGGCAGGGGAGGTAACCCC
ATCGGATAGCGGGGGGCAAGAGGACTCTCCAGCCAAAGGGCTCTCCGTAAGGCTGGAGTTTGACTATTCTGAGGACAAGAGTAGTTGGGACAACCAGCAG
GAAAACCCCCCTCCTACCAAAAAGATAGGCAAAAAGCCAGTTGCCAAAATGCCCCTGAGGAGGCCAAAGATGAAAAAGACACCCGAGAAACTTGACAACA
CTCCTGCCTCACCTCCCAGATCCCCTGCTGAACCCAATGACATCCCCATTGCTAAAGGTACTTACACCTTTGATATTGACAAGTGGGATGACCCCAATTT
TAACCCTTTTTCTTCCACCTCAAAAATGCAGGAGTCTCCCAAACTGCCCCAACAATCATACAACTTTGACCCAGACACCTGTGATGAGTCCGTTGACCCC
TTTAAGACATCCTCTAAGACCCCCAGCTCACCTTCTAAATCCCCAGCCTCCTTTGAGATCCCAGCCAGTGCTATGGAAGCCAATGGAGTGGACGGGGATG
GGCTAAACAAGCCCGCCAAGAAGAAGAAGACGCCCCTAAAGACTGACACATTTAGGGTGAAAAAGTCGCCAAAACGGTCTCCTCTCTCTGATCCACCTTC
CCAGGACCCCACCCCAGCTGCTACACCAGAAACACCACCAGTGATCTCTGCGGTGGTCCACGCCACAGATGAGGAAAAGCTGGCGGTCACCAACCAGAAG
TGGACGTGCATGACAGTGGACCTAGAGGCTGACAAACAGGACTACCCGCAGCCCTCGGACCTGTCCACCTTTGTAAACGAGACCAAATTCAGTTCACCCA
CTGAGGAGTTGGATTACAGAAACTCCTATGAAATTGAATATATGGAGAAAATTGGCTCCTCCTTACCTCAGGACGACGATGCCCCGAAGAAGCAGGCCTT
GTACCTTATGTTTGACACTTCTCAGGAGAGCCCTGTCAAGTCATCTCCCGTCCGCATGTCAGAGTCCCCGACGCCGTGTTCAGGGTCAAGTTTTGAAGAG
ACTGAAGCCCTTGTGAACACTGCTGCGAAAAACCAGCATCCTGTCCCACGAGGACTGGCCCCTAACCAAGAGTCACACTTGCAGGTGCCAGAGAAATCCT
CCCAGAAGGAGCTGGAGGCCATGGGCTTGGGCACCCCTTCAGAAGCGATTGAAATTACAGCTCCCGAGGGCTCCTTTGCCTCTGCTGACGCCCTCCTCAG
CAGGCTAGCTCACCCCGTCTCTCTCTGTGGTGCACTTGACTATCTGGAGCCCGACTTAGCAGAAAAGAACCCCCCACTATTCGCTCAGAAACTCCAGGAG
GAGTTAGAGTTTGCCATCATGCGGATAGAAGCCCTGAAGCTGGCCAGGCAGATTGCTTTGGCTTCCCGCAGCCACCAGGATGCCAAGAGAGAGGCTGCTC
ACCCAACAGACGTCTCCATCTCCAAAACAGCCTTGTACTCCCGCATCGGGACCGCTGAGGTGGAGAAACCTGCAGGCCTTCTGTTCCAGCAGCCCGACCT
GGACTCTGCCCTCCAGATCGCCAGAGCAGAGATCATAACCAAGGAGAGAGAGGTCTCAGAATGGAAAGATAAATATGAAGAAAGCAGGCGGGAAGTGATG
GAAATGAGGAAAATAGTGGCCGAGTATGAGAAGACCATCGCTCAGATGATAGAGGACGAACAGAGAGAGAAGTCAGTCTCCCACCAGACGGTGCAGCAGC
TGGTTCTGGAGAAGGAGCAAGCCCTGGCCGACCTGAACTCCGTGGAGAAGTCTCTGGCCGACCTCTTCAGAAGATATGAGAAGATGAAGGAGGTCCTAGA
AGGCTTCCGCAAGAATGAAGAGGTGTTGAAGAGATGTGCGCAGGAGTACCTGTCCCGGGTGAAGAAGGAGGAGCAGAGGTACCAGGCCCTGAAGGTGCAC
GCGGAGGAGAAACTGGACAGGGCCAATGCTGAGATTGCTCAGGTTCGAGGCAAGGCCCAGCAGGAGCAAGCCGCCCACCAGGCCAGCCTGCGGAAGGAGC
AGCTGCGAGTGGACGCCCTGGAAAGGACGCTGGAGCAGAAGAATAAAGAAATAGAAGAACTCACCAAGATTTGTGACGAACTGATTGCCAAAATGGGGAA
AAGCTAACTCTGAACCGAATGTTTTGGACTTAACTGTTGCGTGCAATATGACCGTCGGCACACTGCTGTTCCTCCAGTTCCATGGACAGGTTCTGTTTTC
ACTTTTTCGTATGCACTACTGTATTTCCTTTCTAAATAAAATTGATTTGATTGTATGCAGTACTAAGGAGACTATCAGAATTTCTTGCTATTGGTTTGCA
TTTTCCTAGTATAATTCATAGCAAGTTGACCTCAGAGTTCCTGTATCAGGGAGATTGTCTGATTCTCTAATAAAAGACACATTGCTGACCTTGGCCTTGC
CCTTTGTACACAAGTTCCCAGGGTGAGCAGCTTTTGGATTTAATATGAACATGTACAGCGTGCATAGGGACTCTTGCCTTAAGGAGTGTAAACTTGATCT
GCATTTGCTGATTTGTTTTTAAAAAAACAAGAAATGCATGTTTCAAATAAAATTCTCTATTGTAAATAAAATTTTTTCTTTGGATCTTGGCAA
  • refseq_TACC2.F4 (forward primer)
  • refseq_TACC2.R4 (reverse primer)
  • Single exon skipping

Frame 0

ACSKGRIRREETQIPEPCQHIKPHIKGCTVHWD
FSSHPLGPLPSILYFLSFLSKTFLKTFTPALKVI
LVSYSTLCPLGEFFPLRREE*SCCCRHIRFPTG
NSWSASPLTKFWGRWEH*INMGNENSTSDNQRT
LSAQTPRSAQPPGNSQNIKRKQQDTPGSPDHRDA
SSIGSVGLGGFCTASESSASLDPCLVSPEVTEP
RKDPQGARGPEGSLLPSPPPSQEREHPSSSMPF
AECPPEGCLASPAAAPEDGPQTQSPRREPAPNAP
GDIAAAFPAERDSSTPYQEIAAVPSAGRERQPK
EEGQKSSFSFSSGIDQSPGMSPVPLREPMKAPL
CGEGDQPGGFESQEKEAAGGFPPAESRQGVASVQ
VTPEAPAAAQQGTESSAVLEKSPLKPMAPIPQD
PAPRASDRERGQGEAPPQYLTDDLEFLRACHLP
RSNSGAAPEAEVNAASQESCQQPVGAYLPHAELP
WGLPSPALVPEAGGSGKEALDTIDVQGHPQTGM
RGTKPNQVVCVAAGGQPEGGLPVSPEPSLLTPT
EEAHPASSLASFPAAQIPIAVEEPGSSSRESVSK
AGMPVSADAAKEVVDAGLVGLERQVSDLGSKGE
HPEGDPGEVPAPSPQERGEHLNTEQSHEVQPGV
PPPPLPKEQSHEVQPGAPPPPLPKAPSESARGPP
GPTDGAKVHEDSTSPAVAKEGSRSPGDSPGGKE
EAPEPPDGGDPGNLQGEDSQAFSSKRDPEVGKD
ELSKPSSDAESRDHPSSHSAQPPRKGGAGHTDGP
HSQTAEADASGLPHKLGEEDPVLPPVPDGAGEP
TVPEGAIWEGSGLQPKCPDTLQSREGLGRMESF
LTLESEKSDFPPTPVAEVAPKAQEGESTLEIRKM
GSCDGEGLLTSPDQPRGPACDASRQEFHAGVPH
PPQGENLAADLGLTALILDQDQQGIPSCPGEGW
IRGAASEWPLLSSEKHLQPSQAQPETSIFDVLKE
QAQPPENGKETSPSHPGFKDQGADSSQIHVPVE
PQEDNNLPTHGGQEQALGSELQSQLPKGTLSDT
PTSSPTDMVWESSLTEESELSAPTRQKLPALGEK
RPEGACGDGQSSRVSPPAADVLKDFSLAGNFSR
KETCCTGQGPNKSQQALADALEEGSQHEEACQR
HPGASEAADGCSPLWGLSKREMASGNTGEAPPCQ
PDSVALLDAVPCLPALAPASPGVTPTQDAPETE
ACDETQEGRQQPVPAPQQKMECWATSDAESPKL
LASFPSAGEQGGEAGAAETGGSAGAGDPGKQQAP
EKPGEATLSCGLLQTEHCLTSGEEASTSALRES
CQAEHPMASCQDALLPARELGGIPRSTMDFSTH
QAVPDPKELLLSGPPEVAAPDTPYLHVDSAAQRG
AEDSGVKAVSSADPRAPGESPCPVGEPPLALEN
AASLKLFAGSLAPLLQPGAAGGEIPAVQASSGS
PKARTTEGPVDSMPCLDRMPLLAKGKQATGEEKA
ATAPGAGAKASGEGMAGDAAGETEGSMERMGEP
SQDPKQGTSGGVDTSSEQIATLTGFPDFREHIA
KIFEKPVLGALATPGEKAGAGRSAVGKDLTRPLG
PEKLLDGPPGVDVTLLPAPPARLQVEKKQQLAG
EAEISHLALQDPASDKLLGPAGLTWERNLPGAG
VGKEMAGVPPTLREDERPEGPGAAWPGLEGQAYS
QLERSRQELASGLPSPAATQELPVERAAAFQVA
PHSHGEEAVAQDRIPSGKQHQETSACDSPHGED
GPGDFAHTGVPGHVPRSTCAPSPQREVLTVPEAN
SEPWTLDTLGGERRPGVTAGILEMRNALGNQST
PAPPTGEVADTPLEPGKVAGAAGEAEGDITLST
AETQACASGDLPEAGTTRTFSVVAGDLVLPGSCQ
DPACSDKAPGMEGTAALHGDSPARPQQAKEQPG
PERPIPAGDGKVCVSSPPEPDETHDPKLQHLAP
EELHTDRESPRPGPSMLPSVPKKDAPRVMDKVTS
DETRGAEGTESSPVADDIIQPAAPADLESPTLA
ASSY
HGDVVGQVSTDLIAQSISPAAAHAGLPPS
AAEHIVSPSAPAGDRVEASTPSCPDPAKDLSR
SS
DSEEAFETPESTTPVKAPPAPPPPPPEVIPEPE
VSTQPPPEEPGCGSETVPVPDGPRSDSVEGSPF
RPPSHSFSAVFDEDKPIASSGTYNLDFDNIELVD
TFQTLEPRASDAKNQEGKVNTRRKSTDSVPISK
STLSRSLSLQASDFDGASSSGNPEAVALAPDAY
STGSSSASSTLKRTKKPRPPSLKKKQTTKKPTET
PPVKETQQEPDEESLVPSGENLASETKTESAKT
EGPSPALLEETPLEPAVGPKAACPLDSESAEGV
VPPASGGGRVQNSPPVGRKTLPLTTAPEAGEVTP
SDSGGQEDSPAKGLSVRLEFDYSEDKSSWDNQQ
ENPPPTKKIGKKPVAKMPLRRPKMKKTPEKLDN
TPASPPRSPAEPNDIPIAKGTYTFDIDKWDDPNF
NPFSSTSKMQESPKLPQQSYNFDPDTCDESVDP
FKTSSKTPSSPSKSPASFEIPASAMEANGVDGD
GLNKPAKKKKTPLKTDTFRVKKSPKRSPLSDPPS
QDPTPAATPETPPVISAVVHATDEEKLAVTNQK
WTCMTVDLEADKQDYPQPSDLSTFVNETKFSSP
TEELDYRNSYEIEYMEKIGSSLPQDDDAPKKQAL
YLMFDTSQESPVKSSPVRMSESPTPCSGSSFEE
TEALVNTAAKNQHPVPRGLAPNQESHLQVPEKS
SQKELEAMGLGTPSEAIEITAPEGSFASADALLS
RLAHPVSLCGALDYLEPDLAEKNPPLFAQKLQE
ELEFAIMRIEALKLARQIALASRSHQDAKREAA
HPTDVSISKTALYSRIGTAEVEKPAGLLFQQPDL
DSALQIARAEIITKEREVSEWKDKYEESRREVM
EMRKIVAEYEKTIAQMIEDEQREKSVSHQTVQQ
LVLEKEQALADLNSVEKSLADLFRRYEKMKEVLE
GFRKNEEVLKRCAQEYLSRVKKEEQRYQALKVH
AEEKLDRANAEIAQVRGKAQQEQAAHQASLRKE
QLRVDALERTLEQKNKEIEELTKICDELIAKMGK
S*L*TECFGLNCCVQYDRRHTAVPPVPWTGSVF
TFSYALLYFLSK*N*FDCMQY*GDYQNFLLLVC
IFLV*FIAS*PQSSCIREIV*FSNKRHIADLGLA
LCTQVPRVSSFWI*YEHVQRA*GLLP*GV*T*S
AFADLFLKKQEMHVSNKILYCK*NFFFGSWQ

Frame 1

PAPREGSGEKKRKSQNRANI*NPTLRVVQCTGI
SQVTRLVLFQVYFTSFHSSLKLF*KLSLLL*KL
SWFLTLPYAPWANFFL*GGKNRVAAADTSDSLLV
TAGVRHL*QNSGDAGNTESTWAMRTAPRTTRGL
YQLRLQGPRSHPGTVRI*KGSSRTRPEALTTET
RPALAALGLEASAPLLRVLPAWIHALCPQR*LSQ
GRTHREPGGQKVLCCPAHHRPRSESTPRPPCPL
PSVPRKVAWQVQQRHLKMVLRLSLPGGNLPQMP
QETSRRHFPLRGTALLHTKRLLPSPVLEERDSRR
KKDRSPPSPSPVASTSHLECRQYPSESQ*RHRC
VERGTSLVVLSPKRKRLQVAFPLQSPGRGWLLC
K*PLRPLLQPSRAQKAQRSWRSPP*NPWPRSHKI
QPQEPQTEKEAKGRRRLSI*QMTWNSSGPAISL
GAIQGLPQKQK*MPLPRRAASSQWEHICRTQSC
PGACQVLPWCQRLGALGRRLWTPLMFRVTHRQGC
EEPSPIKLSVWQQAASPKGVCL*ALNLPCSLRL
RKHIQLQASLHSQLLRFLLL*KNLDHHPGNQFP
RLGCQFLQMQPKRWWMQGWWDWRGRCQILEARES
IQKGTLERFLPHHPRRGEST*TRSKAMRSNQEY
HPLLFPRSKAMRSNQEHHPLLFPRHQVKVPEGH
RGQRMEPRSMKIPQAQPWLKKEADHLVTALEERR
KPQSHLMVETQGTCKERTLRLSAASVIQK*AKM
SFQSQAVMQRAETIPAHTQHSHPERGVLGTRTG
PTLRQQRLMHLAYHTSWVRRTPSCPLCQMELVSP
LFPKEPSGRGQDCSPNVLTPFRAGKDWEEWSLS
*L*NQRNQIFHQLLLQRLHPKPRKVRAHWK*GR
WAAVMGRAC*RPQINPAGRRVMRRDRNFMLGCHI
PPRGRTWQQTWGSRHSSWTKISRESHPAQGKAG
*EELHPSGPYYLLRSISSHPRHNQRHPSLTCSR
SRPSHLKMGKRLLQAIQVLRTREQILPKSMYLWN
LRKITTCPLMEDRSRLWDQNFKVSSPKAPCLIL
QLHLPLTWFGRVL*QKSQNCQHQRDRSCLH*GR
SGQREHAVMVSPRGSRLQQQMS*KTFLLQGTSAE
RKLAALGRGQTSLNRHWLMPWKKAASMKKHVKG
IQELLKQLMVVPHSGA*VRGRWQVETQGRPHLV
SLTQ*LSWMQFPACQPWRPPAPESHPPRMPQRQR
HVMKPRKAGSNQCRPRSRKWSAGPLRMQSPQSF
LQVSHQLGSKVVKPGLLRLVAALVQETQESSRL
RRNLEKLL*VVASFRLSTALPPGRKLLPLPYVSP
AKLSTPWPAARMPCCQPESWVGFPGAPWIFLHT
RLSQTQRSSCCLGHQKWLLLTPLTCMSTVLPRE
EQKTVE*KLFPLQTPELLAKAPVL*GSPHLPWKM
LPP*SCLLAPSPPCCNQELQVGKSLQCKPAVVV
PKPEPLRDQWTPCHAWTGCHFWPRASRQQGKRK
QQQLQVQVPRPVGRAWQVMQQERQRAAWRGWESL
PRTQSRAHQVVWTQALSKSPPSLASQTSGSTSP
RSSRSLCSEPWPHLEKRQELGGVQWVKTSPGHW
AQRSF*MGLQEWMSPFSLHLLLDSRWRRSNSWLE
RLRFPIWLCKIQLQTSFWVQQG*PGSGTCQVPV
WGRRWQVSHPH*GKTRGQRGLGQPGQAWKARLT
HSWRGAGRN*LQVFLHQQLLRSSLWRELLPSRWL
PIAMEKRPWPKTEFLLESSTRKHLPATVHMEKM
VPGTLLTQGFQDMCQGPRVPLLLRGRF*LCLRP
TVSPGPLTRLGVKGDPESLLASWKCEMPWATRAP
LHHQLEKWQTLPWSLARWQALLGKQRVTSP*AQ
LRHRHVRPVICLKQVLRGHSPLWQVTWCCQEAV
RTQPALTRLRGWRVQLPFMGTAQPGPSRLRSSQG
LSAPFQLGMGRCASPHLQSLTKLTTRSCNIWLQ
KSSTLTERAPGLAHPCYLRFLRRMLQESWIKSL
QMRPEVRKEQKVHLWQMISSSPLPPQTWKAQP*L
PLPT
TVMLLARSLRI**PRASPQLLPMRVFLPR
LQNT*FRHLPQLVTE*KLPLPPAQIRPRTSA
GV
PILKRHLRPRSQRPLSKLRQLHPHHPPKSSQNPR
SAHSHPRKNQDVVLRQSLSLMAHGATRWKEVPS
VPRHTPSLPSSMKTSR*PAVGLTTWTLTTLSLW
IPFRPWSLVPQTLRIRRAK*THGGSPRIPSPSLS
LHCPGRSACKPVTLMVLLPQAIPRPWPLPQMHI
ARVPAVLLVPLSELKNRGRLP*KRNRPPRNPQR
PPQ*RRRNRSQMKRALSPVGRI*HLRRKRNLPRR
KVLAQPYWRRRPLSPLWGPKLPALWTQRVQKGL
SPRLLEVAECRTHPLSGGKRCLLPRPRRQGR*P
HRIAGGKRTLQPKGSP*GWSLTILRTRVVGTTSR
KTPLLPKR*AKSQLPKCP*GGQR*KRHPRNLTT
LLPHLPDPLLNPMTSPLLKVLTPLILTSGMTPI
LTLFLPPQKCRSLPNCPNNHTTLTQTPVMSPLTP
LRHPLRPPAHLLNPQPPLRSQPVLWKPMEWTGM
G*TSPPRRRRRP*RLTHLG*KSRQNGLLSLIHL
PRTPPQLLHQKHHQ*SLRWSTPQMRKSWRSPTRS
GRA*QWT*RLTNRTTRSPRTCPPL*TRPNSVHP
LRSWITETPMKLNIWRKLAPPYLRTTMPRRSRP
CTLCLTLLRRALSSHLPSACQSPRRRVQGQVLKR
LKPL*TLLRKTSILSHEDWPLTKSHTCRCQRNP
PRRSWRPWAWAPLQKRLKLQLPRAPLPLLTPSS
AG*LTPSLSVVHLTIWSPT*QKRTPHYSLRNSRR
S*SLPSCG*KP*SWPGRLLWLPAATRMPRERLL
TQQTSPSPKQPCTPASGPLRWRNLQAFCSSSPT
WTLPSRSPEQRS*PRRERSQNGKINMKKAGGK*W
K*GK*WPSMRRPSLR**RTNRERSQSPTRRCSS
WFWRRSKPWPT*TPWRSLWPTSSEDMRR*RRS*
KASARMKRC*RDVRRSTCPG*RRRSRGTRP*RCT
RRRNWTGPMLRLLRFEARPSRSKPPTRPACGRS
SCEWTPWKGRWSRRIKK*KNSPRFVTN*LPKWG
KANSEPNVLDLTVACNMTVGTLLFLQFHGQVLFS
LFRMHYCISFLNKIDLIVCSTKETIRISCYWFA
FS*YNS*QVDLRVPVSGRLSDSLIKDTLLTLAL
PFVHKFPG*AAFGFNMNMYSVHRDSCLKECKLDL
HLLICF*KNKKCMFQIKFSIVNKIFSLDLG

Frame 2

LLQGKDQERRNANPRTVPTYKTPH*GLYSALGF
LKSPAWSSSKYTLLPFIPL*NFFKNFHSCSKSY
LGFLLYLMPLGRIFSSEEGRIELLLQTHQIPYW
*QLECVTSDKILGTLGTLNQHGQ*EQHLGQPEDF
ISSDSKVRAATREQSEYKKEAAGHARKP*PQRR
VQHWQRWAWRLLHRF*EFCQPGSMPCVPRGD*A
KEGPTGSQGARRFFAAQPTTVPGARAPLVLHALC
RVSPGRLLGKSSSGT*RWSSDSVSQEGTCPKCP
RRHRGGISR*EGQLYSIPRDCCRPQCWKRETAE
GRRTEVLLLLLQWHRPVTWNVASTPQRANEGTAV
WRGGPAWWF*VPRERGCRWLSPCRVQAGGGFCA
SDP*GPCCSPAGHRKLSGLGEVPPKTHGPDPTR
SSPKSLRQRKRPRGGAASVFNR*LGIPQGLPSP*
EQFRGCPRSRSECRFPGELPAASGSISAARRAA
LGLAKSCPGARGWGLWEGGSGHH*CSGSPTDRD
ARNQAQSSCLCGSRRPARRGFACEP*TFPAHSD*
GSTSSFKPRFIPSCSDSYCCRRTWIIIQGISFQ
GWDASFCRCSQRGGGCRVGGTGEAGVRSWKQGR
ASRRGPWRGSCPITPGEGRALEHGAKP*GPTRST
TPSSSQGAKP*GPTRSTTPSSSQGTK*KCQRAT
GANGWSQGP*RFHKPSRG*RRKQITW*QPWRKG
GSPRAT*WWRPREPARRGLSGFQQQA*SRSRQR*
AFKAKQ*CREQRPSQLTLSTATQKGGCWAHGRA
PLSDSRG*CIWPTTQAG*GGPRPAPCARWSW*A
HCSRRSHLGGVRIAAQMS*HPSEQGRIGKNGVFP
DFRIREIRFSTNSCCRGCTQSPGR*EHIGNKED
GQL*WGGLADVPRSTPRAGV*CVETGISCWGAT
SPPGGELGSRPGAHGTHPGPRSAGNPILPRGRLD
KRSCIRVAPTIF*EASPAIPGTTRDIHL*RAQG
AGPAT*KWERDFSKPSRF*GPGSRFFPNPCTCG
TSGR*QLAHSWRTGAGFGIRTSKSAPQRHPV*YS
NFISH*HGLGEFSDRRVRIVSTNETEVACTRGE
AARGSMR*WSVLEGLASSSRCLKRLFSCRELQQ
KGNLLHWAGAKQVSTGIG*CLGRRQPA*RSMSKA
SRSF*SS*WLFPTLGLE*EGDGKWKHRGGPTLS
A*LSSSPGCSSLPASPGARQPRSHTHPGCPRDR
GM**NPGRQAATSAGPAAENGVLGHFGCRVPKAS
CKFPISWGARW*SRGC*DWWQRWCRRPRKAAGS
GETWRSYFELWPPSD*ALPYLRGGSFYLCPT*V
LPS*APHGQLPGCLAASQRAGWDSQEHHGFFYTP
GCPRPKGAPAVWATRSGCS*HPLPACRQCCPER
SRRQWSESCFLCRPQSSWRKPLSCRGAPTCLGK
CCLLEAVCWLPRPPVATRSCRWGNPCSASQQW*S
QSQNH*GTSGLHAMPGPDATSGQGQAGNRGRES
SNSSRCRCQGQWGGHGR*CSRRDRGQHGEDGRA
FPGPKAGHIRWCGHKL*ANRHPHWLPRLQGAHRQ
DLREACARSPGHTWRKGRSWEECSG*RPHQAIG
PREASRWASRSGCHPSPCTSCSTPGGEEATVGW
RG*DFPSGSARSSFRQASGSSRADLGAELARCRC
GEGDGRCPTHTEGRREARGAWGSLARPGRPGLL
TAGEEQAGISFRSSFTSSYSGAPCGESCCLPGG
SP*PWRRGRGPRQNSFWKAAPGNICLRQSTWRRW
SRGLCSHRGSRTCAKVHVCPFSSEGGFDCA*GQ
Q*ALDP*HAWG*KETRSHCWHLGNAKCPGQPEH
PCTTNWRSGRHSPGAWQGGRRCWGSRG*HHPEHS
*DTGMCVR*SA*SRYYEDILRCGR*LGAARKLS
GPSLL*QGSGDGGYSCPSWGQPSQAPAG*GAAR
A*APHSSWGWEGVRLLTSRA*RNSRPEAATFGSR
RAPH*QREPQAWPIHVTFGS*EGCSKSHG*SHF
R*DQRCGRNRKFTCGR*YHPARCPRRPGKPNLS
CLFLP
R*CCWPGLYGSDSPEHLPSCCPCGSSSLG
CRTHSFAICPSW*QSRSFHSLLPRSGQGPQQ
EF
RF*RGI*DPGVNDPCQSSASSTPTTPRSHPRTR
GQHTATPGRTRMWF*DSPCP*WPTERLGGRKSLP
SPVTLLLCRLR*RQADSQQWDLQLGL*QH*ACG
YLSDLGASCLRR*ESGGQSEHTEEVHGFRPHL*
VYTVPVAQPASQ*L*WCFFLRQSRGRGPCPRCI*
HGFQQCF*YP*AN*KTEAAFLKKETDHQETHRD
PPSEGDATGAR*REPCPQWGESSI*DENGICQD
GRS*PSLIGGDAP*ARCGAQSCLPSGLRECRRGC
PPGFWRWQSAELTPCREENAASYHGPGGRGGNP
IG*RGARGLSSQRALRKAGV*LF*GQE*LGQPA
GKPPSYQKDRQKASCQNAPEEAKDEKDTRET*QH
SCLTSQIPC*TQ*HPHC*RYLHL*Y*QVG*PQF
*PFFFHLKNAGVSQTAPTIIQL*PRHL**VR*P
L*DIL*DPQLTF*IPSLL*DPSQCYGSQWSGRGW
AKQARQEEEDAPKD*HI*GEKVAKTVSSL*STF
PGPHPSCYTRNTTSDLCGGPRHR*GKAGGHQPE
VDVHDSGPRG*QTGLPAALGPVHLCKRDQIQFTH
*GVGLQKLL*N*IYGENWLLLTSGRRCPEEAGL
VPYV*HFSGEPCQVISRPHVRVPDAVFRVKF*R
D*SPCEHCCEKPASCPTRTGP*PRVTLAGAREIL
PEGAGGHGLGHPFRSD*NYSSRGLLCLC*RPPQ
QASSPRLSLWCT*LSGARLSRKEPPTIRSETPG
GVRVCHHADRSPEAGQADCFGFPQPPGCQERGCS
PNRRLHLQNSLVLPHRDR*GGETCRPSVPAARP
GLCPPDRQSRDHNQGERGLRMER*I*RKQAGSD
GNEENSGRV*EDHRSDDRGRTEREVSLPPDGAAA
GSGEGASPGRPELRGEVSGRPLQKI*EDEGGPR
RLPQE*RGVEEMCAGVPVPGEEGGAEVPGPEGA
RGGETGQGQC*DCSGSRQGPAGASRPPGQPAEGA
AASGRPGKDAGAEE*RNRRTHQDL*RTDCQNGE
KLTLNRMFWT*LLRAI*PSAHCCSSSSMDRFCF
HFFVCTTVFPF*IKLI*LYAVLRRLSEFLAIGLH
FPSIIHSKLTSEFLYQGDCLIL**KTHC*PWPC
PLYTSSQGEQLLDLI*TCTACIGTLALRSVNLI
CIC*FVFKKTRNACFK*NSLL*IKFFLWILA

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