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Sequences

Sequence NM_199003

GAGGTTGAAGCTGCCTCCGCCATCTTGGAGATGGGAGACGGGCGATGGCTGTGGTCCTTCTGCTAATGCAAACAACAAAACGGGCACACTAGTCACCCCC
GAGGGAGGCCACCATCACTGTAACTGTTGGCCAAAGCTACAAAAGAAGCGAGGGAATCCAACCGAGCGCAGCGACACTGAGAACAGCTTCCCCTGCCTTC
TGCGGCGGCAGAAGTGAAGTGCCTGAGGACCGGAAGGATGGTGCAGTCCTGCTCCGCCTACGGCTGCAAGAACCGCTACGACAAGGACAAGCCCGTTTCT
TTC
CACAAAAAGAAGATCTTCTGGAGCCACAGGAACAGCTTCCCCCACCTCCTTTACCGCCTCCTGTTTCCCAGGTTGATGCTGCTATTGGATTACTAAT
GCCGCCTCTTCAGACCCCTGTTAATCTCTCAGTTTTCTGTGACCACAACTATACTGTGGAGGATACAATGCACCAGCGGAAAAGGATTCATCAGCTAGAA
CAGCAAGTTGAAAAACTCAGAAAGAAGCTCAAGACCGCACAGCAGCGATGCAGAAGGCAAGAACGGCAGCTTGAAAAATTAAAGGAGGTTGTTCACTTCC
AGAAAGAGAAAGACGACGTATCAGAAAGAGGTTATGTGATTCTACCAAATGACTACTTTGAAATAGTTGAAGTACCAGCATAAAAAAATGAAATGTGTAT
TGATTTCTAATGGGGCAATACCACATATCCTCCTCTAGCCTGTAAAGGAGTTTCATTTAAAAAAATAACATTTGATTACTTATATAAAAACAGTTCAGAA
TATTTTTTTAAAAAAAATTCTATATATACTGTAAAATTATAAATTTTTTTGTTTGTAATTTCAGGTTTTTTACATTTTAACAAAATATTTTAAAAGTTAT
AAACTAACCTCAGACCTCTAATGTAAGTTGGTTTCAAGATTGGGGATTTTGGGGTTTTTTTTTAGTATTTATAGAAATAATGTAAAAATAAAAAGTAAAG
AGAATGAGAACAGTGTGGTAAAAGGGTGATTTCAGTTTAAAACTTAAAATTAGTACTGTTTTATTGAGAGAATTTAGTTATATTTTAAATCAGAAGTATG
GGTCAGATCATGGGACATAACTTCTTAGAATATATATATACATATGTACATATTCTCATATGTAAAGTCACAAGGTTCATTTATCTTTCTGAATCAGTTA
TCAAAGATAAATTGGCAAGTCAGTACTTAAGAAAAAAGATTTGATTATCATCACAGCAGAAAAAAGTCATTGCATATCTGATCAATAACTTCAGATTCTA
AGAGTGGATTTTTTTTTTTTACATGGGCTCCTATTTTTTCCCCTACTGTCTTGCATTATAAAATTAGAAGTGTATTTTCAGTGGAAGAAACATTTTTCAA
TAAATAAAGTAAGGCATTGTCATCAATGAAGTAATTAAAACTGGGACCTGATCTATGATACGCTTTTTTCTTTCATTACACCCTAGCTGAAGGACATCCA
GTTCCCCAGCTGTAGTTATGTATCTGCCTTCAAGTCTCTGACAAATGTGCTGTGTTAGTAGAGTTTGATTTGTATCATATGATAATCTTGCACTTGACTG
AGTTGGGACAAGGCTTCACATAAAAAATTATTTCTTCACTTTTAACACAAGTTAGAAATTATATCCCATTTAGTTAAGTGCGTGATTTATATTCAGAACA
ACCTACTATGTAGCGTTTATTTTACTGAATGTGGAGATTTAAACACTGAGGTTTCTGTTCAAACTGTGAGTTCTGTTCTTTGTGAGAAATTTTACATATA
TTGGAAGTGAAAATATGTTCTGAGTAAACAAATATTGCTATGGGAGTTATCTTTTTAGATTTAGAATAACTGTTCCAATGATAATTATTACTTTTATATT
TCAAAGTACACTAAGATCGTTGAAGAGCAATAGAACCTTTAAGACAGTATTAAAGGTGTGAAACAATGGCA
  • refseq_THAP1.F1 (forward primer)
  • refseq_THAP1.R1 (reverse primer)
  • Single exon skipping

Frame 0

EVEAASAILEMGDGRWLWSFC*CKQQNGHTSHP
RGRPPSL*LLAKATKEARESNRAQRH*EQLPLPS
AAAEVKCLRTGRMVQSCSAYGCKNRYDKDKPVS
F
HKKKIFWSHRNSFPHLLYRLLFPRLMLLLDY*
CRLFRPLLISQFSVTTTILWRIQCTSGKGFIS*N
SKLKNSERSSRPHSSDAEGKNGSLKN*RRLFTS
RKRKTTYQKEVM*FYQMTTLK*LKYQHKKMKCV
LISNGAIPHILL*PVKEFHLKK*HLITYIKTVQN
IFLKKILYIL*NYKFFCL*FQVFYILTKYFKSY
KLTSDL*CKLVSRLGILGFFFSIYRNNVKIKSK
ENENSVVKG*FQFKT*N*YCFIERI*LYFKSEVW
VRSWDITS*NIYIHMYIFSYVKSQGSFIFLNQL
SKINWQVST*EKRFDYHHSRKKSLHI*SITSDS
KSGFFFFTWAPIFSPTVLHYKIRSVFSVEETFFN
K*SKALSSMK*LKLGPDL*YAFFFHYTLAEGHP
VPQL*LCICLQVSDKCAVLVEFDLYHMIILHLT
ELGQGFT*KIISSLLTQVRNYIPFS*VRDLYSEQ
PTM*RLFY*MWRFKH*GFCSNCEFCSL*EILHI
LEVKICSE*TNIAMGVIFLDLE*LFQ**LLLLY
FKVH*DR*RAIEPLRQY*RCETMA

Frame 1

RLKLPPPSWRWETGDGCGPSANANNKTGTLVTP
EGGHHHCNCWPKLQKKRGNPTERSDTENSFPCL
LRRQK*SA*GPEGWCSPAPPTAARTATTRTSPFL
S
TKRRSSGATGTASPTSFTASCFPG*CCYWITN
AASSDPC*SLSFL*PQLYCGGYNAPAEKDSSAR
TAS*KTQKEAQDRTAAMQKARTAA*KIKGGCSLP
ERERRRIRKRLCDSTK*LL*NS*STSIKK*NVY
*FLMGQYHISSSSL*RSFI*KNNI*LLI*KQFR
IFF*KKFYIYCKIINFFVCNFRFFTF*QNILKVI
N*PQTSNVSWFQDWGFWGFFLVFIEIM*K*KVK
RMRTVW*KGDFSLKLKISTVLLREFSYILNQKY
GSDHGT*LLRIYIYICTYSHM*SHKVHLSF*ISY
QR*IGKSVLKKKDLIIITAEKSHCISDQ*LQIL
RVDFFFLHGLLFFPLLSCIIKLEVYFQWKKHFS
INKVRHCHQ*SN*NWDLIYDTLFSFITP*LKDIQ
FPSCSYVSAFKSLTNVLC**SLICII**SCT*L
SWDKASHKKLFLHF*HKLEIISHLVKCVIYIQN
NLLCSVYFTECGDLNTEVSVQTVSSVLCEKFYIY
WK*KYVLSKQILLWELSF*I*NNCSNDNYYFYI
SKYTKIVEEQ*NL*DSIKGVKQW

Frame 2

G*SCLRHLGDGRRAMAVVLLLMQTTKRAH*SPP
REATITVTVGQSYKRSEGIQPSAATLRTASPAF
CGGRSEVPEDRKDGAVLLRLRLQEPLRQGQARF
F
PQKEDLLEPQEQLPPPPLPPPVSQVDAAIGLLM
PPLQTPVNLSVFCDHNYTVEDTMHQRKRIHQLE
QQVEKLRKKLKTAQQRCRRQERQLEKLKEVVHF
QKEKDDVSERGYVILPNDYFEIVEVPA*KNEMCI
DF*WGNTTYPPLACKGVSFKKITFDYLYKNSSE
YFFKKNSIYTVKL*IFLFVISGFLHFNKIF*KL
*TNLRPLM*VGFKIGDFGVFF*YL*K*CKNKK*R
E*EQCGKRVISV*NLKLVLFY*ENLVIF*IRSM
GQIMGHNFLEYIYTYVHILICKVTRFIYLSESV
IKDKLASQYLRKKI*LSSQQKKVIAYLINNFRF*
EWIFFFYMGSYFFPYCLAL*N*KCIFSGRNIFQ
*IK*GIVINEVIKTGT*SMIRFFLSLHPS*RTS
SSPAVVMYLPSSL*QMCCVSRV*FVSYDNLALD*
VGTRLHIKNYFFTFNTS*KLYPI*LSA*FIFRT
TYYVAFILLNVEI*TLRFLFKL*VLFFVRNFTY
IGSENMF*VNKYCYGSYLFRFRITVPMIIITFIF
QSTLRSLKSNRTFKTVLKV*NNG

Sequence NM_018105

GAGGTTGAAGCTGCCTCCGCCATCTTGGAGATGGGAGACGGGCGATGGCTGTGGTCCTTCTGCTAATGCAAACAACAAAACGGGCACACTAGTCACCCCC
GAGGGAGGCCACCATCACTGTAACTGTTGGCCAAAGCTACAAAAGAAGCGAGGGAATCCAACCGAGCGCAGCGACACTGAGAACAGCTTCCCCTGCCTTC
TGCGGCGGCAGAAGTGAAGTGCCTGAGGACCGGAAGGATGGTGCAGTCCTGCTCCGCCTACGGCTGCAAGAACCGCTACGACAAGGACAAGCCCGTTTCT
TTC
CACAAGTTTCCTCTTACTCGACCCAGTCTTTGTAAAGAATGGGAGGCAGCTGTCAGAAGAAAAAACTTTAAACCCACCAAGTATAGCAGTATTTGTT
CAGAGCACTTTACTCCAGACTGCTTTAAGAGAGAGTGCAACAACAAGTTACTGAAAGAGAATGCTGTGCCCACAATATTTCTTTGTACTGAGCCACATGA
CAAG
AAAGAAGATCTTCTGGAGCCACAGGAACAGCTTCCCCCACCTCCTTTACCGCCTCCTGTTTCCCAGGTTGATGCTGCTATTGGATTACTAATGCCG
CCTCTTCAGACCCCTGTTAATCTCTCAGTTTTCTGTGACCACAACTATACTGTGGAGGATACAATGCACCAGCGGAAAAGGATTCATCAGCTAGAACAGC
AAGTTGAAAAACTCAGAAAGAAGCTCAAGACCGCACAGCAGCGATGCAGAAGGCAAGAACGGCAGCTTGAAAAATTAAAGGAGGTTGTTCACTTCCAGAA
AGAGAAAGACGACGTATCAGAAAGAGGTTATGTGATTCTACCAAATGACTACTTTGAAATAGTTGAAGTACCAGCATAAAAAAATGAAATGTGTATTGAT
TTCTAATGGGGCAATACCACATATCCTCCTCTAGCCTGTAAAGGAGTTTCATTTAAAAAAATAACATTTGATTACTTATATAAAAACAGTTCAGAATATT
TTTTTAAAAAAAATTCTATATATACTGTAAAATTATAAATTTTTTTGTTTGTAATTTCAGGTTTTTTACATTTTAACAAAATATTTTAAAAGTTATAAAC
TAACCTCAGACCTCTAATGTAAGTTGGTTTCAAGATTGGGGATTTTGGGGTTTTTTTTTAGTATTTATAGAAATAATGTAAAAATAAAAAGTAAAGAGAA
TGAGAACAGTGTGGTAAAAGGGTGATTTCAGTTTAAAACTTAAAATTAGTACTGTTTTATTGAGAGAATTTAGTTATATTTTAAATCAGAAGTATGGGTC
AGATCATGGGACATAACTTCTTAGAATATATATATACATATGTACATATTCTCATATGTAAAGTCACAAGGTTCATTTATCTTTCTGAATCAGTTATCAA
AGATAAATTGGCAAGTCAGTACTTAAGAAAAAAGATTTGATTATCATCACAGCAGAAAAAAGTCATTGCATATCTGATCAATAACTTCAGATTCTAAGAG
TGGATTTTTTTTTTTTACATGGGCTCCTATTTTTTCCCCTACTGTCTTGCATTATAAAATTAGAAGTGTATTTTCAGTGGAAGAAACATTTTTCAATAAA
TAAAGTAAGGCATTGTCATCAATGAAGTAATTAAAACTGGGACCTGATCTATGATACGCTTTTTTCTTTCATTACACCCTAGCTGAAGGACATCCAGTTC
CCCAGCTGTAGTTATGTATCTGCCTTCAAGTCTCTGACAAATGTGCTGTGTTAGTAGAGTTTGATTTGTATCATATGATAATCTTGCACTTGACTGAGTT
GGGACAAGGCTTCACATAAAAAATTATTTCTTCACTTTTAACACAAGTTAGAAATTATATCCCATTTAGTTAAGTGCGTGATTTATATTCAGAACAACCT
ACTATGTAGCGTTTATTTTACTGAATGTGGAGATTTAAACACTGAGGTTTCTGTTCAAACTGTGAGTTCTGTTCTTTGTGAGAAATTTTACATATATTGG
AAGTGAAAATATGTTCTGAGTAAACAAATATTGCTATGGGAGTTATCTTTTTAGATTTAGAATAACTGTTCCAATGATAATTATTACTTTTATATTTCAA
AGTACACTAAGATCGTTGAAGAGCAATAGAACCTTTAAGACAGTATTAAAGGTGTGAAACAATGGCA
  • refseq_THAP1.F1 (forward primer)
  • refseq_THAP1.R1 (reverse primer)
  • Single exon skipping

Frame 0

EVEAASAILEMGDGRWLWSFC*CKQQNGHTSHP
RGRPPSL*LLAKATKEARESNRAQRH*EQLPLPS
AAAEVKCLRTGRMVQSCSAYGCKNRYDKDKPVS
F
HKFPLTRPSLCKEWEAAVRRKNFKPTKYSSIC
SEHFTPDCFKRECNNKLLKENAVPTIFLCTEPHD
K
KEDLLEPQEQLPPPPLPPPVSQVDAAIGLLMP
PLQTPVNLSVFCDHNYTVEDTMHQRKRIHQLEQ
QVEKLRKKLKTAQQRCRRQERQLEKLKEVVHFQK
EKDDVSERGYVILPNDYFEIVEVPA*KNEMCID
F*WGNTTYPPLACKGVSFKKITFDYLYKNSSEY
FFKKNSIYTVKL*IFLFVISGFLHFNKIF*KL*T
NLRPLM*VGFKIGDFGVFF*YL*K*CKNKK*RE
*EQCGKRVISV*NLKLVLFY*ENLVIF*IRSMG
QIMGHNFLEYIYTYVHILICKVTRFIYLSESVIK
DKLASQYLRKKI*LSSQQKKVIAYLINNFRF*E
WIFFFYMGSYFFPYCLAL*N*KCIFSGRNIFQ*
IK*GIVINEVIKTGT*SMIRFFLSLHPS*RTSSS
PAVVMYLPSSL*QMCCVSRV*FVSYDNLALD*V
GTRLHIKNYFFTFNTS*KLYPI*LSA*FIFRTT
YYVAFILLNVEI*TLRFLFKL*VLFFVRNFTYIG
SENMF*VNKYCYGSYLFRFRITVPMIIITFIFQ
STLRSLKSNRTFKTVLKV*NNG

Frame 1

RLKLPPPSWRWETGDGCGPSANANNKTGTLVTP
EGGHHHCNCWPKLQKKRGNPTERSDTENSFPCL
LRRQK*SA*GPEGWCSPAPPTAARTATTRTSPFL
S
TSFLLLDPVFVKNGRQLSEEKTLNPPSIAVFV
QSTLLQTALRESATTSY*KRMLCPQYFFVLSHM
TR
KKIFWSHRNSFPHLLYRLLFPRLMLLLDY*CR
LFRPLLISQFSVTTTILWRIQCTSGKGFIS*NS
KLKNSERSSRPHSSDAEGKNGSLKN*RRLFTSR
KRKTTYQKEVM*FYQMTTLK*LKYQHKKMKCVLI
SNGAIPHILL*PVKEFHLKK*HLITYIKTVQNI
FLKKILYIL*NYKFFCL*FQVFYILTKYFKSYK
LTSDL*CKLVSRLGILGFFFSIYRNNVKIKSKEN
ENSVVKG*FQFKT*N*YCFIERI*LYFKSEVWV
RSWDITS*NIYIHMYIFSYVKSQGSFIFLNQLS
KINWQVST*EKRFDYHHSRKKSLHI*SITSDSKS
GFFFFTWAPIFSPTVLHYKIRSVFSVEETFFNK
*SKALSSMK*LKLGPDL*YAFFFHYTLAEGHPV
PQL*LCICLQVSDKCAVLVEFDLYHMIILHLTEL
GQGFT*KIISSLLTQVRNYIPFS*VRDLYSEQP
TM*RLFY*MWRFKH*GFCSNCEFCSL*EILHIL
EVKICSE*TNIAMGVIFLDLE*LFQ**LLLLYFK
VH*DR*RAIEPLRQY*RCETMA

Frame 2

G*SCLRHLGDGRRAMAVVLLLMQTTKRAH*SPP
REATITVTVGQSYKRSEGIQPSAATLRTASPAF
CGGRSEVPEDRKDGAVLLRLRLQEPLRQGQARF
F
PQVSSYSTQSL*RMGGSCQKKKL*THQV*QYLF
RALYSRLL*ERVQQQVTERECCAHNISLY*AT*
Q
ERRSSGATGTASPTSFTASCFPG*CCYWITNA
ASSDPC*SLSFL*PQLYCGGYNAPAEKDSSARTA
S*KTQKEAQDRTAAMQKARTAA*KIKGGCSLPE
RERRRIRKRLCDSTK*LL*NS*STSIKK*NVY*
FLMGQYHISSSSL*RSFI*KNNI*LLI*KQFRIF
F*KKFYIYCKIINFFVCNFRFFTF*QNILKVIN
*PQTSNVSWFQDWGFWGFFLVFIEIM*K*KVKR
MRTVW*KGDFSLKLKISTVLLREFSYILNQKYGS
DHGT*LLRIYIYICTYSHM*SHKVHLSF*ISYQ
R*IGKSVLKKKDLIIITAEKSHCISDQ*LQILR
VDFFFLHGLLFFPLLSCIIKLEVYFQWKKHFSIN
KVRHCHQ*SN*NWDLIYDTLFSFITP*LKDIQF
PSCSYVSAFKSLTNVLC**SLICII**SCT*LS
WDKASHKKLFLHF*HKLEIISHLVKCVIYIQNNL
LCSVYFTECGDLNTEVSVQTVSSVLCEKFYIYW
K*KYVLSKQILLWELSF*I*NNCSNDNYYFYIS
KYTKIVEEQ*NL*DSIKGVKQW

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