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Sequences

Sequence NM_198310

GACGCCGCCAGCTCTTCACTCCACGCCCACCTCTCTCCTGGAGCGCTGGGCCTTCGCTGGCCGCACCGGCAGCCATGAGCTCGGAGATGGAGCCGCTGCT CCTGGCCTGGAGCTATTTTAGGCGCAGGAAGTTCCAGCTCTGCGCCGATCTATGCACGCAGATGCTGGAGAAGTCCCCTTATGACCAGGCAGCTTGGATC TTAAAAGCAAGAGCGCTAACAGAAATGGTATACATAGATGAAATTGATGTAGATCAGGAAGGAATTGCAGAAATGATGCTGGATGAAAATGCTATAGCTC AAGTTCCACGCCCTGGAACGTCTTTGAAACTCCCTGGAACTAATCAGACAGGAGGGCCTAGCCAGGCCGTTAGGCCAATCACACAAGCTGGAAGACCCAT TACAGGTTTCCTCAGGCCCAGCACGCAGAGTGGAAGGCCAGGCACTATGGAACAGGCTATCAGAACACCCAGAACCGCCTACACAGCCCGCCCTATCACC AGCTCCTCCGGAAGATTTGTCAGGCTGGGAACGGCTTTGTTTGAGTATATCTTTCATCATGAAAATGATGTTAAGACTGCTTTGGATCTGGCTGCCCTCT CCACAGAACATTCTCAGTACAAGGACTGGTGGTGGAAAGTACAGATTGGAAAATGTTACTACAGGTTGGGAATGTATCGTGAAGCAGAAAAACAGTTTAA ATCAGCCCTGAAGCAGCAGGAAATGGTAGATACATTTCTGTACTTGGCAAAAGTTTATGTCTCATTGGATCAACCTGTGACTGCTTTAAATCTTTTCAAA CAAGGCTTAGATAAGTTTCCAGGAGAAGTAACCCTGCTCTGTGGAATTGCAAGAATCTATGAGGAAATGAACAATATGTCATCAGCAGCAGAATATTACA AAGAAGTTTTGAAACAAGACAATACTCATGTGGAAGCCATCGCATGCATTGGAAGCAACCACTTCTATTCTGATCAGCCAGAAATAGCTCTCCGGTTTTA CAGGCGGCTGCTGCAGATGGGCATTTATAACGGCCAGCTTTTTAACAATCTGGGGCTGTGTTGCTTCTATGCCCAGCAGTATGATATGACTCTGACCTCA TTTGAACGTGCCCTTTCTTTGGCTGAAAATGAAGAAGAGGCAGCTGATGTCTGGTACAACTTGGGACATGTAGCTGTGGGAATAGGAGATACAAATTTGG CCCATCAGTGCTTCAGGCTGGCTCTGGTCAACAACAACAACCACGCCGAGGCCTACAACAACCTGGCTGTGCTGGAGATGCGGAAGGGCCACGTTGAACA GGCAAGGGCACTATTACAAACTGCATCATCATTAGCACCCCATATGTATGAACCGCATTTTAATTTTGCAACAATCTCTGATAAGATTGGAGATCTGCAG AGAAGCTATGTTGCTGCGCAGAAGTCTGAAGCAGCATTTCCAGACCATGTGGACACACAACATTTAATTAAACAATTAAGGCAGCATTTTGCTATGCTCT GATTGTTCCTTAGACCACATATGTTCTTATGAAGCAGCATTATGCAAGGGGAAAAAAGCACTATGTCTGTGTATGTATGTATATAGTGTAATACGTATAT TTTAACAAACCTGTCCTTGATATTAGTTAAGGTGACACATAAGGGTGACACAGAATGTGTAATGCAAATTTCATAGTAATAGTAACTTTATAAAATAATA TTATAAAATACAGGATTTAAACCTTTCTAAATAGATCCTGAAACTGTCTCTCACATTATATAGTAGATGTTTGTTTATAATGTTTACAAAACATTTTGGT GAATTTCCTCAATGTTTTATAAATGTACATTTTTTAAGTCCTTAAGCTGACTCTTAGCCATCATGTAGCTTAAGGAGTCTGAAATCTGCCATTAAAACTG CACCTTTAAGCCAGGTGTGGTAGCATGTGCCTATAGTCCCAGCTACTTGGGAGGTGGAGGTGGGAGGATTATAAATAGAGACTTTCCTTAAGACTTTAAA AATGTATTTAAAACTATTTTTTATTAAATACTTTGTGATTTCCTATTAAGCTTTAAAATAAATCATTGTGTAAAACACCATCA

refseq_TTC8.F2 (forward primer)
refseq_TTC8.R2 (reverse primer)
Single exon skipping

Sequence Tools

Translations

Frame 0

DAASSSLHAHLSPGALGLRWPHRQP*ARRWSRC SWPGAILGAGSSSSAPIYARRCWRSPLMTRQLGS *KQER*QKWYT*MKLM*IRKELQK*CWMKML*L KFHALERL*NSLELIRQEGLARPLGQSHKLEDP LQVSSGPARRVEGQALWNRLSEHPEPPTQPALSP APPEDLSGWERLCLSISFIMKMMLRLLWIWLPS PQNILSTRTGGGKYRLENVTTGWECIVKQKNSL NQP*SSRKW*IHFCTWQKFMSHWINL*LL*IFSN KA*ISFQEK*PCSVELQESMRK*TICHQQQNIT KKF*NKTILMWKPSHALEATTSILISQK*LSGF TGGCCRWAFITASFLTIWGCVASMPSSMI*L*PH LNVPFLWLKMKKRQLMSGTTWDM*LWE*EIQIW PISASGWLWSTTTTTPRPTTTWLCWRCGRATLN RQGHYYKLHHH*HPICMNRILILQQSLIRLEICR EAMLLRRSLKQHFQTMWTHNI*LNN*GSILLCS DCSLDHICSYEAALCKGKKALCLCMYVYSVIRI F*QTCP*Y*LR*HIRVTQNV*CKFHSNSNFIK*Y YKIQDLNLSK*ILKLSLTLYSRCLFIMFTKHFG EFPQCFINVHFLSP*ADS*PSCSLRSLKSAIKT APLSQVW*HVPIVPATWEVEVGGL*IETFLKTLK MYLKLFFIKYFVISY*ALK*IIV*NTI

Frame 1

TPPALHSTPTSLLERWAFAGRTGSHELGDGAAA PGLELF*AQEVPALRRSMHADAGEVPL*PGSLD LKSKSANRNGIHR*N*CRSGRNCRNDAG*KCYSS SSTPWNVFETPWN*SDRRA*PGR*ANHTSWKTH YRFPQAQHAEWKARHYGTGYQNTQNRLHSPPYH QLLRKICQAGNGFV*VYLSS*K*C*DCFGSGCPL HRTFSVQGLVVESTDWKMLLQVGNVS*SRKTV* ISPEAAGNGRYISVLGKSLCLIGSTCDCFKSFQ TRLR*VSRRSNPALWNCKNL*GNEQYVISSRILQ RSFETRQYSCGSHRMHWKQPLLF*SARNSSPVL QAAAADGHL*RPAF*QSGAVLLLCPAV*YDSDL I*TCPFFG*K*RRGS*CLVQLGTCSCGNRRYKFG PSVLQAGSGQQQQPRRGLQQPGCAGDAEGPR*T GKGTITNCIIISTPYV*TAF*FCNNL**DWRSA EKLCCCAEV*SSISRPCGHTTFN*TIKAAFCYAL IVP*TTYVLMKQHYARGKKHYVCVCMYIV*YVY FNKPVLDIS*GDT*G*HRMCNANFIVIVTL*NN IIKYRI*TFLNRS*NCLSHYIVDVCL*CLQNILV NFLNVL*MYIF*VLKLTLSHHVA*GV*NLPLKL HL*ARCGSMCL*SQLLGRWRWEDYK*RLSLRL* KCI*NYFLLNTL*FPIKL*NKSLCKTPS

Frame 2

RRQLFTPRPPLSWSAGPSLAAPAAMSSEMEPLL LAWSYFRRRKFQLCADLCTQMLEKSPYDQAAWI LKARALTEMVYIDEIDVDQEGIAEMMLDENAIA QVPRPGTSLKLPGTNQTGGPSQAVRPITQAGRPI TGFLRPSTQSGRPGTMEQAIRTPRTAYTARPIT SSSGRFVRLGTALFEYIFHHENDVKTALDLAAL STEHSQYKDWWWKVQIGKCYYRLGMYREAEKQFK SALKQQEMVDTFLYLAKVYVSLDQPVTALNLFK QGLDKFPGEVTLLCGIARIYEEMNNMSSAAEYY KEVLKQDNTHVEAIACIGSNHFYSDQPEIALRFY RRLLQMGIYNGQLFNNLGLCCFYAQQYDMTLTS FERALSLAENEEEAADVWYNLGHVAVGIGDTNL AHQCFRLALVNNNNHAEAYNNLAVLEMRKGHVEQ ARALLQTASSLAPHMYEPHFNFATISDKIGDLQ RSYVAAQKSEAAFPDHVDTQHLIKQLRQHFAML *LFLRPHMFL*SSIMQGEKSTMSVYVCI*CNTYI LTNLSLILVKVTHKGDTECVMQIS****LYKII L*NTGFKPF*IDPETVSHII**MFVYNVYKTFW *ISSMFYKCTFFKSLS*LLAIM*LKESEICH*NC TFKPGVVACAYSPSYLGGGGGRIINRDFP*DFK NVFKTIFY*ILCDFLLSFKINHCVKHH

Sequence NM_198309

GACGCCGCCAGCTCTTCACTCCACGCCCACCTCTCTCCTGGAGCGCTGGGCCTTCGCTGGCCGCACCGGCAGCCATGAGCTCGGAGATGGAGCCGCTGCT CCTGGCCTGGAGCTATTTTAGGCGCAGGAAGTTCCAGCTCTGCGCCGATCTATGCACGCAGATGCTGGAGAAGTCCCCTTATGACCAGGCAGCTTGGATC TTAAAAGCAAGAGCGCTAACAGAAATGGTATACATAGATGAAATTGATGTAGATCAGGAAGGAATTGCAGAAATGATGCTGGATGAAAATGCTATAGCTC AAGTTCCACGCCCTGGAACGTCTTTGAAACTCCCTGGAACTAATCAGACAGGAGGGCCTAGCCAGGCCGTTAGGCCAATCACACAAGCTGGAAGACCCAT TACAGGTTTCCTCAGGCCCAGCACGCAGAGTGGAAGGCCAGGCACTATGGAACAGGCTATCAGAACACCCAGAACCGCCTACACAGCCCGCCCTATCACC AGCTCCTCCGGAAGATTTGTCAGGCTGGGAACGGCTTCCATGCTTACAAGTCCTGATGGACCATTTATAAATTTATCTAGGCTGAATTTAACAAAGTATT CCCAGAAACCTAAGTTGGCAAAGGCTTTGTTTGAGTATATCTTTCATCATGAAAATGATGTTAAGACTGCTTTGGATCTGGCTGCCCTCTCCACAGAACA TTCTCAGTACAAGGACTGGTGGTGGAAAGTACAGATTGGAAAATGTTACTACAGGTTGGGAATGTATCGTGAAGCAGAAAAACAGTTTAAATCAGCCCTG AAGCAGCAGGAAATGGTAGATACATTTCTGTACTTGGCAAAAGTTTATGTCTCATTGGATCAACCTGTGACTGCTTTAAATCTTTTCAAACAAGGCTTAG ATAAGTTTCCAGGAGAAGTAACCCTGCTCTGTGGAATTGCAAGAATCTATGAGGAAATGAACAATATGTCATCAGCAGCAGAATATTACAAAGAAGTTTT GAAACAAGACAATACTCATGTGGAAGCCATCGCATGCATTGGAAGCAACCACTTCTATTCTGATCAGCCAGAAATAGCTCTCCGGTTTTACAGGCGGCTG CTGCAGATGGGCATTTATAACGGCCAGCTTTTTAACAATCTGGGGCTGTGTTGCTTCTATGCCCAGCAGTATGATATGACTCTGACCTCATTTGAACGTG CCCTTTCTTTGGCTGAAAATGAAGAAGAGGCAGCTGATGTCTGGTACAACTTGGGACATGTAGCTGTGGGAATAGGAGATACAAATTTGGCCCATCAGTG CTTCAGGCTGGCTCTGGTCAACAACAACAACCACGCCGAGGCCTACAACAACCTGGCTGTGCTGGAGATGCGGAAGGGCCACGTTGAACAGGCAAGGGCA CTATTACAAACTGCATCATCATTAGCACCCCATATGTATGAACCGCATTTTAATTTTGCAACAATCTCTGATAAGATTGGAGATCTGCAGAGAAGCTATG TTGCTGCGCAGAAGTCTGAAGCAGCATTTCCAGACCATGTGGACACACAACATTTAATTAAACAATTAAGGCAGCATTTTGCTATGCTCTGATTGTTCCT TAGACCACATATGTTCTTATGAAGCAGCATTATGCAAGGGGAAAAAAGCACTATGTCTGTGTATGTATGTATATAGTGTAATACGTATATTTTAACAAAC CTGTCCTTGATATTAGTTAAGGTGACACATAAGGGTGACACAGAATGTGTAATGCAAATTTCATAGTAATAGTAACTTTATAAAATAATATTATAAAATA CAGGATTTAAACCTTTCTAAATAGATCCTGAAACTGTCTCTCACATTATATAGTAGATGTTTGTTTATAATGTTTACAAAACATTTTGGTGAATTTCCTC AATGTTTTATAAATGTACATTTTTTAAGTCCTTAAGCTGACTCTTAGCCATCATGTAGCTTAAGGAGTCTGAAATCTGCCATTAAAACTGCACCTTTAAG CCAGGTGTGGTAGCATGTGCCTATAGTCCCAGCTACTTGGGAGGTGGAGGTGGGAGGATTATAAATAGAGACTTTCCTTAAGACTTTAAAAATGTATTTA AAACTATTTTTTATTAAATACTTTGTGATTTCCTATTAAGCTTTAAAATAAATCATTGTGTAAAACACCATCA

refseq_TTC8.F2 (forward primer)
refseq_TTC8.R2 (reverse primer)
Single exon skipping

Sequence Tools

Translations

Frame 0

DAASSSLHAHLSPGALGLRWPHRQP*ARRWSRC SWPGAILGAGSSSSAPIYARRCWRSPLMTRQLGS *KQER*QKWYT*MKLM*IRKELQK*CWMKML*L KFHALERL*NSLELIRQEGLARPLGQSHKLEDP LQVSSGPARRVEGQALWNRLSEHPEPPTQPALSP APPEDLSGWERLPCLQVLMDHL*IYLG*I*QSI PRNLSWQRLCLSISFIMKMMLRLLWIWLPSPQN ILSTRTGGGKYRLENVTTGWECIVKQKNSLNQP* SSRKW*IHFCTWQKFMSHWINL*LL*IFSNKA* ISFQEK*PCSVELQESMRK*TICHQQQNITKKF *NKTILMWKPSHALEATTSILISQK*LSGFTGGC CRWAFITASFLTIWGCVASMPSSMI*L*PHLNV PFLWLKMKKRQLMSGTTWDM*LWE*EIQIWPIS ASGWLWSTTTTTPRPTTTWLCWRCGRATLNRQGH YYKLHHH*HPICMNRILILQQSLIRLEICREAM LLRRSLKQHFQTMWTHNI*LNN*GSILLCSDCS LDHICSYEAALCKGKKALCLCMYVYSVIRIF*QT CP*Y*LR*HIRVTQNV*CKFHSNSNFIK*YYKI QDLNLSK*ILKLSLTLYSRCLFIMFTKHFGEFP QCFINVHFLSP*ADS*PSCSLRSLKSAIKTAPLS QVW*HVPIVPATWEVEVGGL*IETFLKTLKMYL KLFFIKYFVISY*ALK*IIV*NTI

Frame 1

TPPALHSTPTSLLERWAFAGRTGSHELGDGAAA PGLELF*AQEVPALRRSMHADAGEVPL*PGSLD LKSKSANRNGIHR*N*CRSGRNCRNDAG*KCYSS SSTPWNVFETPWN*SDRRA*PGR*ANHTSWKTH YRFPQAQHAEWKARHYGTGYQNTQNRLHSPPYH QLLRKICQAGNGFHAYKS*WTIYKFI*AEFNKVF PET*VGKGFV*VYLSS*K*C*DCFGSGCPLHRT FSVQGLVVESTDWKMLLQVGNVS*SRKTV*ISP EAAGNGRYISVLGKSLCLIGSTCDCFKSFQTRLR *VSRRSNPALWNCKNL*GNEQYVISSRILQRSF ETRQYSCGSHRMHWKQPLLF*SARNSSPVLQAA AADGHL*RPAF*QSGAVLLLCPAV*YDSDLI*TC PFFG*K*RRGS*CLVQLGTCSCGNRRYKFGPSV LQAGSGQQQQPRRGLQQPGCAGDAEGPR*TGKG TITNCIIISTPYV*TAF*FCNNL**DWRSAEKLC CCAEV*SSISRPCGHTTFN*TIKAAFCYALIVP *TTYVLMKQHYARGKKHYVCVCMYIV*YVYFNK PVLDIS*GDT*G*HRMCNANFIVIVTL*NNIIKY RI*TFLNRS*NCLSHYIVDVCL*CLQNILVNFL NVL*MYIF*VLKLTLSHHVA*GV*NLPLKLHL* ARCGSMCL*SQLLGRWRWEDYK*RLSLRL*KCI* NYFLLNTL*FPIKL*NKSLCKTPS

Frame 2

RRQLFTPRPPLSWSAGPSLAAPAAMSSEMEPLL LAWSYFRRRKFQLCADLCTQMLEKSPYDQAAWI LKARALTEMVYIDEIDVDQEGIAEMMLDENAIA QVPRPGTSLKLPGTNQTGGPSQAVRPITQAGRPI TGFLRPSTQSGRPGTMEQAIRTPRTAYTARPIT SSSGRFVRLGTASMLTSPDGPFINLSRLNLTKY SQKPKLAKALFEYIFHHENDVKTALDLAALSTEH SQYKDWWWKVQIGKCYYRLGMYREAEKQFKSAL KQQEMVDTFLYLAKVYVSLDQPVTALNLFKQGL DKFPGEVTLLCGIARIYEEMNNMSSAAEYYKEVL KQDNTHVEAIACIGSNHFYSDQPEIALRFYRRL LQMGIYNGQLFNNLGLCCFYAQQYDMTLTSFER ALSLAENEEEAADVWYNLGHVAVGIGDTNLAHQC FRLALVNNNNHAEAYNNLAVLEMRKGHVEQARA LLQTASSLAPHMYEPHFNFATISDKIGDLQRSY VAAQKSEAAFPDHVDTQHLIKQLRQHFAML*LFL RPHMFL*SSIMQGEKSTMSVYVCI*CNTYILTN LSLILVKVTHKGDTECVMQIS****LYKIIL*N TGFKPF*IDPETVSHII**MFVYNVYKTFW*ISS MFYKCTFFKSLS*LLAIM*LKESEICH*NCTFK PGVVACAYSPSYLGGGGGRIINRDFP*DFKNVF KTIFY*ILCDFLLSFKINHCVKHH

Sequence NM_144596

GACGCCGCCAGCTCTTCACTCCACGCCCACCTCTCTCCTGGAGCGCTGGGCCTTCGCTGGCCGCACCGGCAGCCATGAGCTCGGAGATGGAGCCGCTGCT CCTGGCCTGGAGCTATTTTAGGCGCAGGAAGTTCCAGCTCTGCGCCGATCTATGCACGCAGATGCTGGAGAAGTCCCCTTATGACCAGGAACCAGATCCT GAATTGCCAGTGCATCAGGCAGCTTGGATCTTAAAAGCAAGAGCGCTAACAGAAATGGTATACATAGATGAAATTGATGTAGATCAGGAAGGAATTGCAG AAATGATGCTGGATGAAAATGCTATAGCTCAAGTTCCACGCCCTGGAACGTCTTTGAAACTCCCTGGAACTAATCAGACAGGAGGGCCTAGCCAGGCCGT TAGGCCAATCACACAAGCTGGAAGACCCATTACAGGTTTCCTCAGGCCCAGCACGCAGAGTGGAAGGCCAGGCACTATGGAACAGGCTATCAGAACACCC AGAACCGCCTACACAGCCCGCCCTATCACCAGCTCCTCCGGAAGATTTGTCAGGCTGGGAACGGCTTCCATGCTTACAAGTCCTGATGGACCATTTATAA ATTTATCTAGGCTGAATTTAACAAAGTATTCCCAGAAACCTAAGTTGGCAAAGGCTTTGTTTGAGTATATCTTTCATCATGAAAATGATGTTAAGACTGC TTTGGATCTGGCTGCCCTCTCCACAGAACATTCTCAGTACAAGGACTGGTGGTGGAAAGTACAGATTGGAAAATGTTACTACAGGTTGGGAATGTATCGT GAAGCAGAAAAACAGTTTAAATCAGCCCTGAAGCAGCAGGAAATGGTAGATACATTTCTGTACTTGGCAAAAGTTTATGTCTCATTGGATCAACCTGTGA CTGCTTTAAATCTTTTCAAACAAGGCTTAGATAAGTTTCCAGGAGAAGTAACCCTGCTCTGTGGAATTGCAAGAATCTATGAGGAAATGAACAATATGTC ATCAGCAGCAGAATATTACAAAGAAGTTTTGAAACAAGACAATACTCATGTGGAAGCCATCGCATGCATTGGAAGCAACCACTTCTATTCTGATCAGCCA GAAATAGCTCTCCGGTTTTACAGGCGGCTGCTGCAGATGGGCATTTATAACGGCCAGCTTTTTAACAATCTGGGGCTGTGTTGCTTCTATGCCCAGCAGT ATGATATGACTCTGACCTCATTTGAACGTGCCCTTTCTTTGGCTGAAAATGAAGAAGAGGCAGCTGATGTCTGGTACAACTTGGGACATGTAGCTGTGGG AATAGGAGATACAAATTTGGCCCATCAGTGCTTCAGGCTGGCTCTGGTCAACAACAACAACCACGCCGAGGCCTACAACAACCTGGCTGTGCTGGAGATG CGGAAGGGCCACGTTGAACAGGCAAGGGCACTATTACAAACTGCATCATCATTAGCACCCCATATGTATGAACCGCATTTTAATTTTGCAACAATCTCTG ATAAGATTGGAGATCTGCAGAGAAGCTATGTTGCTGCGCAGAAGTCTGAAGCAGCATTTCCAGACCATGTGGACACACAACATTTAATTAAACAATTAAG GCAGCATTTTGCTATGCTCTGATTGTTCCTTAGACCACATATGTTCTTATGAAGCAGCATTATGCAAGGGGAAAAAAGCACTATGTCTGTGTATGTATGT ATATAGTGTAATACGTATATTTTAACAAACCTGTCCTTGATATTAGTTAAGGTGACACATAAGGGTGACACAGAATGTGTAATGCAAATTTCATAGTAAT AGTAACTTTATAAAATAATATTATAAAATACAGGATTTAAACCTTTCTAAATAGATCCTGAAACTGTCTCTCACATTATATAGTAGATGTTTGTTTATAA TGTTTACAAAACATTTTGGTGAATTTCCTCAATGTTTTATAAATGTACATTTTTTAAGTCCTTAAGCTGACTCTTAGCCATCATGTAGCTTAAGGAGTCT GAAATCTGCCATTAAAACTGCACCTTTAAGCCAGGTGTGGTAGCATGTGCCTATAGTCCCAGCTACTTGGGAGGTGGAGGTGGGAGGATTATAAATAGAG ACTTTCCTTAAGACTTTAAAAATGTATTTAAAACTATTTTTTATTAAATACTTTGTGATTTCCTATTAAGCTTTAAAATAAATCATTGTGTAAAACACCA TCA

refseq_TTC8.F2 (forward primer)
refseq_TTC8.R2 (reverse primer)
Single exon skipping

Sequence Tools

Translations

Frame 0

DAASSSLHAHLSPGALGLRWPHRQP*ARRWSRC SWPGAILGAGSSSSAPIYARRCWRSPLMTRNQIL NCQCIRQLGS*KQER*QKWYT*MKLM*IRKELQ K*CWMKML*LKFHALERL*NSLELIRQEGLARP LGQSHKLEDPLQVSSGPARRVEGQALWNRLSEHP EPPTQPALSPAPPEDLSGWERLPCLQVLMDHL* IYLG*I*QSIPRNLSWQRLCLSISFIMKMMLRL LWIWLPSPQNILSTRTGGGKYRLENVTTGWECIV KQKNSLNQP*SSRKW*IHFCTWQKFMSHWINL* LL*IFSNKA*ISFQEK*PCSVELQESMRK*TIC HQQQNITKKF*NKTILMWKPSHALEATTSILISQ K*LSGFTGGCCRWAFITASFLTIWGCVASMPSS MI*L*PHLNVPFLWLKMKKRQLMSGTTWDM*LW E*EIQIWPISASGWLWSTTTTTPRPTTTWLCWRC GRATLNRQGHYYKLHHH*HPICMNRILILQQSL IRLEICREAMLLRRSLKQHFQTMWTHNI*LNN* GSILLCSDCSLDHICSYEAALCKGKKALCLCMYV YSVIRIF*QTCP*Y*LR*HIRVTQNV*CKFHSN SNFIK*YYKIQDLNLSK*ILKLSLTLYSRCLFI MFTKHFGEFPQCFINVHFLSP*ADS*PSCSLRSL KSAIKTAPLSQVW*HVPIVPATWEVEVGGL*IE TFLKTLKMYLKLFFIKYFVISY*ALK*IIV*NT I

Frame 1

TPPALHSTPTSLLERWAFAGRTGSHELGDGAAA PGLELF*AQEVPALRRSMHADAGEVPL*PGTRS *IASASGSLDLKSKSANRNGIHR*N*CRSGRNCR NDAG*KCYSSSSTPWNVFETPWN*SDRRA*PGR *ANHTSWKTHYRFPQAQHAEWKARHYGTGYQNT QNRLHSPPYHQLLRKICQAGNGFHAYKS*WTIYK FI*AEFNKVFPET*VGKGFV*VYLSS*K*C*DC FGSGCPLHRTFSVQGLVVESTDWKMLLQVGNVS *SRKTV*ISPEAAGNGRYISVLGKSLCLIGSTCD CFKSFQTRLR*VSRRSNPALWNCKNL*GNEQYV ISSRILQRSFETRQYSCGSHRMHWKQPLLF*SA RNSSPVLQAAAADGHL*RPAF*QSGAVLLLCPAV *YDSDLI*TCPFFG*K*RRGS*CLVQLGTCSCG NRRYKFGPSVLQAGSGQQQQPRRGLQQPGCAGD AEGPR*TGKGTITNCIIISTPYV*TAF*FCNNL* *DWRSAEKLCCCAEV*SSISRPCGHTTFN*TIK AAFCYALIVP*TTYVLMKQHYARGKKHYVCVCM YIV*YVYFNKPVLDIS*GDT*G*HRMCNANFIVI VTL*NNIIKYRI*TFLNRS*NCLSHYIVDVCL* CLQNILVNFLNVL*MYIF*VLKLTLSHHVA*GV *NLPLKLHL*ARCGSMCL*SQLLGRWRWEDYK*R LSLRL*KCI*NYFLLNTL*FPIKL*NKSLCKTP S

Frame 2

RRQLFTPRPPLSWSAGPSLAAPAAMSSEMEPLL LAWSYFRRRKFQLCADLCTQMLEKSPYDQEPDP ELPVHQAAWILKARALTEMVYIDEIDVDQEGIA EMMLDENAIAQVPRPGTSLKLPGTNQTGGPSQAV RPITQAGRPITGFLRPSTQSGRPGTMEQAIRTP RTAYTARPITSSSGRFVRLGTASMLTSPDGPFI NLSRLNLTKYSQKPKLAKALFEYIFHHENDVKTA LDLAALSTEHSQYKDWWWKVQIGKCYYRLGMYR EAEKQFKSALKQQEMVDTFLYLAKVYVSLDQPV TALNLFKQGLDKFPGEVTLLCGIARIYEEMNNMS SAAEYYKEVLKQDNTHVEAIACIGSNHFYSDQP EIALRFYRRLLQMGIYNGQLFNNLGLCCFYAQQ YDMTLTSFERALSLAENEEEAADVWYNLGHVAVG IGDTNLAHQCFRLALVNNNNHAEAYNNLAVLEM RKGHVEQARALLQTASSLAPHMYEPHFNFATIS DKIGDLQRSYVAAQKSEAAFPDHVDTQHLIKQLR QHFAML*LFLRPHMFL*SSIMQGEKSTMSVYVC I*CNTYILTNLSLILVKVTHKGDTECVMQIS** **LYKIIL*NTGFKPF*IDPETVSHII**MFVYN VYKTFW*ISSMFYKCTFFKSLS*LLAIM*LKES EICH*NCTFKPGVVACAYSPSYLGGGGGRIINR DFP*DFKNVFKTIFY*ILCDFLLSFKINHCVKHH