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Sequences

Sequence NM_153282

CTTCCTCCAGGAGTCTCTGGTGCAGCTGGGGTGGAATCTGGCCAGGCCCTGCTTAGGCCCCCATCCTGGGGTCAGGAAATTTGGAGGATAAGGCCCTTCA GCCCCAAGGTTGTCCTCGACCAGTCCCGTGCCATGGCAGCCCACCTGCTTCCCATCTGCGCCCTCTTCCTGACCTTACTCGATATGGCCCAAGGCTTTAG GGGCCCCTTGCTACCCAACCGGCCCTTCACCACCGTCTGGAATGCAAACACCCAGTGGTGCCTGGAGAGGCACGGTGTGGACGTGGATGTCAGTGTCTTC GATGTGGTAGCCAACCCAGGGCAGACCTTCCGCGGCCCTGACATGACAATTTTCTATAGCTCCCAGCTGGGCACCTACCCCTACTACACGCCCACTGGGG AGCCTGTGTTTGGTGGTCTGCCCCAGAATGCCAGCCTGATTGCCCACCTGGCCCGCACATTCCAGGACATCCTGGCTGCCATACCTGCTCCTGACTTCTC AGGGCTGGCAGTCATCGACTGGGAGGCATGGCGCCCACGCTGGGCCTTCAACTGGGACACCAAGGACATTTACCGGCAGCGCTCACGGGCACTGGTACAG GCACAGCACCCTGATTGGCCAGCTCCTCAGGTGGAGGCAGTAGCCCAGGACCAGTTCCAGGGAGCTGCACGGGCCTGGATGGCAGGCACCCTCCAGCTGG GGCGGGCACTGCGTCCTCGCGGCCTCTGGGGCTTCTATGGCTTCCCTGACTGCTACAACTATGACTTTCTAAGCCCCAACTACACCGGCCAGTGCCCATC AGGCATCCGTGCCCAAAATGACCAGCTAGGGTGGCTGTGGGGCCAGAGCCGTGCCCTCTATCCCAGCATCTACATGCCCGCAGTGCTGGAGGGCACAGGG AAGTCACAGATGTATGTGCAACACCGTGTGGCCGAGGCATTCCGTGTGGCTGTGGCTGCTGGTGACCCCAATCTGCCGGTGCTGCCCTATGTCCAGATCT TCTATGACACGACAAACCACTTTCTGCCCCTGGAATCATGTCAGGCCATCAAGGAGTATATGGACACTACACTGGGGCCCTTCATCCTGAACGTGACCAG TGGGGCCCTTCTCTGCAGTCAAGCCCTGTGCTCCGGCCATGGCCGCTGTGTCCGCCGCACCAGCCACCCCAAAGCCCTCCTCCTCCTTAACCCTGCCAGT TTCTCCATCCAGCTCACGCCTGGTGGTGGGCCCCTGAGCCTGCGGGGTGCCCTCTCACTTGAAGATCAGGCACAGATGGCTGTGGAGTTCAAATGTCGAT GCTACCCTGGCTGGCAGGCACCGTGGTGTGAGCGGAAGAGCATGTGGTGATTGGCCACACACTGAGTTGCACATATTGAGAACCTAATGCACTCTGGGTC TGGCCAGGGCTTCCTCAAATACATGCACAGTCATACAAGTCATGGTCACAGTAAAGAGTACACTCAGCCACTGTCACAGGCATATTCCCTGCACACACAT GCATACTTACAGACTGGAATAGTGGCATAAGGAGTTAGAACCACAGCAGACACCATTCATTCCATGTCCATATGCATCTACTTGGCAAGGTCATAGACAA TTCCTCCAGAGACACTGAGCCAGTCTTTGAACTGCAGCAATCACAAAGGCTGACATTCACTGAGTGCCTACTCTTTGCCAATCCCCGTGCTAAGCGTTTT ATGTGGACTTATTCATTCCTCACAATGAGGCTATGAGGAAACTGAGTCACTCACATTGAGAGTAAGCACGTTGCCCAAGGTTGCACAGCAAGAAAAGGGA GAAGTTGAGATTCAAACCCAGGCTGTCTAGCTCCGGGGGTACAGCCCTTGCACTCCTACTGAGTTTGTGGTAACCAGCCCTGCACGACCCCTGAATCTGC TGAGAGGCACCAGTCCAGCAAATAAAGCAGTCATGATTTACTTA

refseq_HYAL1.F1 (forward primer)
refseq_HYAL1.R1 (reverse primer)
Single exon skipping

Frame 0

LPPGVSGAAGVESGQALLRPPSWGQEIWRIRPF SPKVVLDQSRAMAAHLLPICALFLTLLDMAQGFR GPLLPNRPFTTVWNANTQWCLERHGVDVDVSVF DVVANPGQTFRGPDMTIFYSSQLGTYPYYTPTG EPVFGGLPQNASLIAHLARTFQDILAAIPAPDFS GLAVIDWEAWRPRWAFNWDTKDIYRQRSRALVQ AQHPDWPAPQVEAVAQDQFQGAARAWMAGTLQL GRALRPRGLWGFYGFPDCYNYDFLSPNYTGQCPS GIRAQNDQLGWLWGQSRALYPSIYMPAVLEGTG KSQMYVQHRVAEAFRVAVAAGDPNLPVLPYVQI FYDTTNHFLPLESCQAIKEYMDTTLGPFILNVTS GALLCSQALCSGHGRCVRRTSHPKALLLLNPAS FSIQLTPGGGPLSLRGALSLEDQAQMAVEFKCR CYPGWQAPWCERKSMW*LATH*VAHIENLMHSGS GQGFLKYMHSHTSHGHSKEYTQPLSQAYSLHTH AYLQTGIVA*GVRTTADTIHSMSICIYLARS*T IPPETLSQSLNCSNHKG*HSLSAYSLPIPVLSVL CGLIHSSQ*GYEETESLTLRVSTLPKVAQQEKG EVEIQTQAV*LRGYSPCTPTEFVVTSPARPLNL LRGTSPANKAVMIYL

Frame 1

FLQESLVQLGWNLARPCLGPHPGVRKFGG*GPS APRLSSTSPVPWQPTCFPSAPSS*PYSIWPKAL GAPCYPTGPSPPSGMQTPSGAWRGTVWTWMSVSS MW*PTQGRPSAALT*QFSIAPSWAPTPTTRPLG SLCLVVCPRMPA*LPTWPAHSRTSWLPYLLLTS QGWQSSTGRHGAHAGPSTGTPRTFTGSAHGHWYR HSTLIGQLLRWRQ*PRTSSRELHGPGWQAPSSW GGHCVLAASGASMASLTATTMTF*APTTPASAH QASVPKMTS*GGCGARAVPSIPASTCPQCWRAQG SHRCMCNTVWPRHSVWLWLLVTPICRCCPMSRS SMTRQTTFCPWNHVRPSRSIWTLHWGPSS*T*P VGPFSAVKPCAPAMAAVSAAPATPKPSSSLTLPV SPSSSRLVVGP*ACGVPSHLKIRHRWLWSSNVD ATLAGRHRGVSGRACGDWPHTELHILRT*CTLG LARASSNTCTVIQVMVTVKSTLSHCHRHIPCTHM HTYRLE*WHKELEPQQTPFIPCPYASTWQGHRQ FLQRH*ASL*TAAITKADIH*VPTLCQSPC*AF YVDLFIPHNEAMRKLSHSH*E*ARCPRLHSKKRE KLRFKPRLSSSGGTALALLLSLW*PALHDP*IC *EAPVQQIKQS*FT

Frame 2

SSRSLWCSWGGIWPGPA*APILGSGNLEDKALQ PQGCPRPVPCHGSPPASHLRPLPDLTRYGPRL* GPLATQPALHHRLECKHPVVPGEARCGRGCQCL RCGSQPRADLPRP*HDNFL*LPAGHLPLLHAHWG ACVWWSAPECQPDCPPGPHIPGHPGCHTCS*LL RAGSHRLGGMAPTLGLQLGHQGHLPAALTGTGT GTAP*LASSSGGGSSPGPVPGSCTGLDGRHPPAG AGTASSRPLGLLWLP*LLQL*LSKPQLHRPVPI RHPCPK*PARVAVGPEPCPLSQHLHARSAGGHR EVTDVCATPCGRGIPCGCGCW*PQSAGAALCPDL L*HDKPLSAPGIMSGHQGVYGHYTGALHPERDQ WGPSLQSSPVLRPWPLCPPHQPPQSPPPP*PCQ FLHPAHAWWWAPEPAGCPLT*RSGTDGCGVQMSM LPWLAGTVV*AEEHVVIGHTLSCTY*EPNALWV WPGLPQIHAQSYKSWSQ*RVHSATVTGIFPAHT CILTDWNSGIRS*NHSRHHSFHVHMHLLGKVIDN SSRDTEPVFELQQSQRLTFTECLLFANPRAKRF MWTYSFLTMRL*GN*VTHIESKHVAQGCTARKG RS*DSNPGCLAPGVQPLHSY*VCGNQPCTTPESA ERHQSSK*SSHDLL

Sequence NM_153283

CTTCCTCCAGGAGTCTCTGGTGCAGCTGGGGTGGAATCTGGCCAGGCCCTGCTTAGGCCCCCATCCTGGGGTCAGGAAATTTGGAGGATAAGGCCCTTCA GCCCCAAGGACATCCTGGCTGCCATACCTGCTCCTGACTTCTCAGGGCTGGCAGTCATCGACTGGGAGGCATGGCGCCCACGCTGGGCCTTCAACTGGGA CACCAAGGACATTTACCGGCAGCGCTCACGGGCACTGGTACAGGCACAGCACCCTGATTGGCCAGCTCCTCAGGTGGAGGCAGTAGCCCAGGACCAGTTC CAGGGAGCTGCACGGGCCTGGATGGCAGGCACCCTCCAGCTGGGGCGGGCACTGCGTCCTCGCGGCCTCTGGGGCTTCTATGGCTTCCCTGACTGCTACA ACTATGACTTTCTAAGCCCCAACTACACCGGCCAGTGCCCATCAGGCATCCGTGCCCAAAATGACCAGCTAGGGTGGCTGTGGGGCCAGAGCCGTGCCCT CTATCCCAGCATCTACATGCCCGCAGTGCTGGAGGGCACAGGGAAGTCACAGATGTATGTGCAACACCGTGTGGCCGAGGCATTCCGTGTGGCTGTGGCT GCTGGTGACCCCAATCTGCCGGTGCTGCCCTATGTCCAGATCTTCTATGACACGACAAACCACTTTCTGCCCCTGGATGAGCTGGAGCACAGCCTGGGGG AGAGTGCGGCCCAGGGGGCAGCTGGAGTGGTGCTCTGGGTGAGCTGGGAAAATACAAGAACCAAGGAATCATGTCAGGCCATCAAGGAGTATATGGACAC TACACTGGGGCCCTTCATCCTGAACGTGACCAGTGGGGCCCTTCTCTGCAGTCAAGCCCTGTGCTCCGGCCATGGCCGCTGTGTCCGCCGCACCAGCCAC CCCAAAGCCCTCCTCCTCCTTAACCCTGCCAGTTTCTCCATCCAGCTCACGCCTGGTGGTGGGCCCCTGAGCCTGCGGGGTGCCCTCTCACTTGAAGATC AGGCACAGATGGCTGTGGAGTTCAAATGTCGATGCTACCCTGGCTGGCAGGCACCGTGGTGTGAGCGGAAGAGCATGTGGTGATTGGCCACACACTGAGT TGCACATATTGAGAACCTAATGCACTCTGGGTCTGGCCAGGGCTTCCTCAAATACATGCACAGTCATACAAGTCATGGTCACAGTAAAGAGTACACTCAG CCACTGTCACAGGCATATTCCCTGCACACACATGCATACTTACAGACTGGAATAGTGGCATAAGGAGTTAGAACCACAGCAGACACCATTCATTCCATGT CCATATGCATCTACTTGGCAAGGTCATAGACAATTCCTCCAGAGACACTGAGCCAGTCTTTGAACTGCAGCAATCACAAAGGCTGACATTCACTGAGTGC CTACTCTTTGCCAATCCCCGTGCTAAGCGTTTTATGTGGACTTATTCATTCCTCACAATGAGGCTATGAGGAAACTGAGTCACTCACATTGAGAGTAAGC ACGTTGCCCAAGGTTGCACAGCAAGAAAAGGGAGAAGTTGAGATTCAAACCCAGGCTGTCTAGCTCCGGGGGTACAGCCCTTGCACTCCTACTGAGTTTG TGGTAACCAGCCCTGCACGACCCCTGAATCTGCTGAGAGGCACCAGTCCAGCAAATAAAGCAGTCATGATTTACTTA

refseq_HYAL1.F1 (forward primer)
refseq_HYAL1.R1 (reverse primer)
Single exon skipping

Frame 0

LPPGVSGAAGVESGQALLRPPSWGQEIWRIRPF SPKDILAAIPAPDFSGLAVIDWEAWRPRWAFNWD TKDIYRQRSRALVQAQHPDWPAPQVEAVAQDQF QGAARAWMAGTLQLGRALRPRGLWGFYGFPDCY NYDFLSPNYTGQCPSGIRAQNDQLGWLWGQSRAL YPSIYMPAVLEGTGKSQMYVQHRVAEAFRVAVA AGDPNLPVLPYVQIFYDTTNHFLPLDELEHSLG ESAAQGAAGVVLWVSWENTRTKESCQAIKEYMDT TLGPFILNVTSGALLCSQALCSGHGRCVRRTSH PKALLLLNPASFSIQLTPGGGPLSLRGALSLED QAQMAVEFKCRCYPGWQAPWCERKSMW*LATH*V AHIENLMHSGSGQGFLKYMHSHTSHGHSKEYTQ PLSQAYSLHTHAYLQTGIVA*GVRTTADTIHSM SICIYLARS*TIPPETLSQSLNCSNHKG*HSLSA YSLPIPVLSVLCGLIHSSQ*GYEETESLTLRVS TLPKVAQQEKGEVEIQTQAV*LRGYSPCTPTEF VVTSPARPLNLLRGTSPANKAVMIYL

Frame 1

FLQESLVQLGWNLARPCLGPHPGVRKFGG*GPS APRTSWLPYLLLTSQGWQSSTGRHGAHAGPSTG TPRTFTGSAHGHWYRHSTLIGQLLRWRQ*PRTSS RELHGPGWQAPSSWGGHCVLAASGASMASLTAT TMTF*APTTPASAHQASVPKMTS*GGCGARAVP SIPASTCPQCWRAQGSHRCMCNTVWPRHSVWLWL LVTPICRCCPMSRSSMTRQTTFCPWMSWSTAWG RVRPRGQLEWCSG*AGKIQEPRNHVRPSRSIWT LHWGPSS*T*PVGPFSAVKPCAPAMAAVSAAPAT PKPSSSLTLPVSPSSSRLVVGP*ACGVPSHLKI RHRWLWSSNVDATLAGRHRGVSGRACGDWPHTE LHILRT*CTLGLARASSNTCTVIQVMVTVKSTLS HCHRHIPCTHMHTYRLE*WHKELEPQQTPFIPC PYASTWQGHRQFLQRH*ASL*TAAITKADIH*V PTLCQSPC*AFYVDLFIPHNEAMRKLSHSH*E*A RCPRLHSKKREKLRFKPRLSSSGGTALALLLSL W*PALHDP*IC*EAPVQQIKQS*FT

Frame 2

SSRSLWCSWGGIWPGPA*APILGSGNLEDKALQ PQGHPGCHTCS*LLRAGSHRLGGMAPTLGLQLG HQGHLPAALTGTGTGTAP*LASSSGGGSSPGPV PGSCTGLDGRHPPAGAGTASSRPLGLLWLP*LLQ L*LSKPQLHRPVPIRHPCPK*PARVAVGPEPCP LSQHLHARSAGGHREVTDVCATPCGRGIPCGCG CW*PQSAGAALCPDLL*HDKPLSAPG*AGAQPGG ECGPGGSWSGALGELGKYKNQGIMSGHQGVYGH YTGALHPERDQWGPSLQSSPVLRPWPLCPPHQP PQSPPPP*PCQFLHPAHAWWWAPEPAGCPLT*RS GTDGCGVQMSMLPWLAGTVV*AEEHVVIGHTLS CTY*EPNALWVWPGLPQIHAQSYKSWSQ*RVHS ATVTGIFPAHTCILTDWNSGIRS*NHSRHHSFHV HMHLLGKVIDNSSRDTEPVFELQQSQRLTFTEC LLFANPRAKRFMWTYSFLTMRL*GN*VTHIESK HVAQGCTARKGRS*DSNPGCLAPGVQPLHSY*VC GNQPCTTPESAERHQSSK*SSHDLL

Sequence NM_153281

AGATGTGGGGAGCGCCTCTGCCCTGTCGCCCCGTCCGGGATGTGAGGAGCGTCTCTCCCTGGCCGCCCCGTCTGAGAAGTGAGGAGCCCCTCCGCCCAGC AGCCGCCCTGTCTGAGAAGCTAGTCTTGAATTCCTGACCTCAGGTGATCCTCCCGCGTTGGCCTCCCAAAGTGCTGGGATTACAGGCATGAGCCACCACT CCTGGCCCCAGAAAGTGACATTCTTTACTTACCACAGGAGGAAAAGATCCACGAAAGTAAAGTGCCTAGGGCCCATCAATGTCAGATGCAGCCACGTGGA CAAAGAACACTCCCTGAGCACAAGACACGAAAGAACCCGGTCTCCAGTGTCACAAACAGGCCTGCCCAGCAGGGTCTGCCCCTGCCCACCTCCTCCAGCC TAGGTTGTCCTCGACCAGTCCCGTGCCATGGCAGCCCACCTGCTTCCCATCTGCGCCCTCTTCCTGACCTTACTCGATATGGCCCAAGGCTTTAGGGGCC CCTTGCTACCCAACCGGCCCTTCACCACCGTCTGGAATGCAAACACCCAGTGGTGCCTGGAGAGGCACGGTGTGGACGTGGATGTCAGTGTCTTCGATGT GGTAGCCAACCCAGGGCAGACCTTCCGCGGCCCTGACATGACAATTTTCTATAGCTCCCAGCTGGGCACCTACCCCTACTACACGCCCACTGGGGAGCCT GTGTTTGGTGGTCTGCCCCAGAATGCCAGCCTGATTGCCCACCTGGCCCGCACATTCCAGGACATCCTGGCTGCCATACCTGCTCCTGACTTCTCAGGGC TGGCAGTCATCGACTGGGAGGCATGGCGCCCACGCTGGGCCTTCAACTGGGACACCAAGGACATTTACCGGCAGCGCTCACGGGCACTGGTACAGGCACA GCACCCTGATTGGCCAGCTCCTCAGGTGGAGGCAGTAGCCCAGGACCAGTTCCAGGGAGCTGCACGGGCCTGGATGGCAGGCACCCTCCAGCTGGGGCGG GCACTGCGTCCTCGCGGCCTCTGGGGCTTCTATGGCTTCCCTGACTGCTACAACTATGACTTTCTAAGCCCCAACTACACCGGCCAGTGCCCATCAGGCA TCCGTGCCCAAAATGACCAGCTAGGGTGGCTGTGGGGCCAGAGCCGTGCCCTCTATCCCAGCATCTACATGCCCGCAGTGCTGGAGGGCACAGGGAAGTC ACAGATGTATGTGCAACACCGTGTGGCCGAGGCATTCCGTGTGGCTGTGGCTGCTGGTGACCCCAATCTGCCGGTGCTGCCCTATGTCCAGATCTTCTAT GACACGACAAACCACTTTCTGCCCCTGGATGAGCTGGAGCACAGCCTGGGGGAGAGTGCGGCCCAGGGGGCAGCTGGAGTGGTGCTCTGGGTGAGCTGGG AAAATACAAGAACCAAGGAATCATGTCAGGCCATCAAGGAGTATATGGACACTACACTGGGGCCCTTCATCCTGAACGTGACCAGTGGGGCCCTTCTCTG CAGTCAAGCCCTGTGCTCCGGCCATGGCCGCTGTGTCCGCCGCACCAGCCACCCCAAAGCCCTCCTCCTCCTTAACCCTGCCAGTTTCTCCATCCAGCTC ACGCCTGGTGGTGGGCCCCTGAGCCTGCGGGGTGCCCTCTCACTTGAAGATCAGGCACAGATGGCTGTGGAGTTCAAATGTCGATGCTACCCTGGCTGGC AGGCACCGTGGTGTGAGCGGAAGAGCATGTGGTGATTGGCCACACACTGAGTTGCACATATTGAGAACCTAATGCACTCTGGGTCTGGCCAGGGCTTCCT CAAATACATGCACAGTCATACAAGTCATGGTCACAGTAAAGAGTACACTCAGCCACTGTCACAGGCATATTCCCTGCACACACATGCATACTTACAGACT GGAATAGTGGCATAAGGAGTTAGAACCACAGCAGACACCATTCATTCCATGTCCATATGCATCTACTTGGCAAGGTCATAGACAATTCCTCCAGAGACAC TGAGCCAGTCTTTGAACTGCAGCAATCACAAAGGCTGACATTCACTGAGTGCCTACTCTTTGCCAATCCCCGTGCTAAGCGTTTTATGTGGACTTATTCA TTCCTCACAATGAGGCTATGAGGAAACTGAGTCACTCACATTGAGAGTAAGCACGTTGCCCAAGGTTGCACAGCAAGAAAAGGGAGAAGTTGAGATTCAA ACCCAGGCTGTCTAGCTCCGGGGGTACAGCCCTTGCACTCCTACTGAGTTTGTGGTAACCAGCCCTGCACGACCCCTGAATCTGCTGAGAGGCACCAGTC CAGCAAATAAAGCAGTCATGATTTACTTA

refseq_HYAL1.F1 (forward primer)
refseq_HYAL1.R1 (reverse primer)
Single exon skipping

Frame 0

RCGERLCPVAPSGM*GASLPGRPV*EVRSPSAQ QPPCLRS*S*IPDLR*SSRVGLPKCWDYRHEPPL LAPESDILYLPQEEKIHESKVPRAHQCQMQPRG QRTLPEHKTRKNPVSSVTNRPAQQGLPLPTSSS LGCPRPVPCHGSPPASHLRPLPDLTRYGPRL*GP LATQPALHHRLECKHPVVPGEARCGRGCQCLRC GSQPRADLPRP*HDNFL*LPAGHLPLLHAHWGA CVWWSAPECQPDCPPGPHIPGHPGCHTCS*LLRA GSHRLGGMAPTLGLQLGHQGHLPAALTGTGTGT AP*LASSSGGGSSPGPVPGSCTGLDGRHPPAGA GTASSRPLGLLWLP*LLQL*LSKPQLHRPVPIRH PCPK*PARVAVGPEPCPLSQHLHARSAGGHREV TDVCATPCGRGIPCGCGCW*PQSAGAALCPDLL *HDKPLSAPG*AGAQPGGECGPGGSWSGALGELG KYKNQGIMSGHQGVYGHYTGALHPERDQWGPSL QSSPVLRPWPLCPPHQPPQSPPPP*PCQFLHPA HAWWWAPEPAGCPLT*RSGTDGCGVQMSMLPWLA GTVV*AEEHVVIGHTLSCTY*EPNALWVWPGLP QIHAQSYKSWSQ*RVHSATVTGIFPAHTCILTD WNSGIRS*NHSRHHSFHVHMHLLGKVIDNSSRDT EPVFELQQSQRLTFTECLLFANPRAKRFMWTYS FLTMRL*GN*VTHIESKHVAQGCTARKGRS*DS NPGCLAPGVQPLHSY*VCGNQPCTTPESAERHQS SK*SSHDLL

Frame 1

DVGSASALSPRPGCEERLSLAAPSEK*GAPPPS SRPV*EASLEFLTSGDPPALASQSAGITGMSHH SWPQKVTFFTYHRRKRSTKVKCLGPINVRCSHVD KEHSLSTRHERTRSPVSQTGLPSRVCPCPPPPA *VVLDQSRAMAAHLLPICALFLTLLDMAQGFRG PLLPNRPFTTVWNANTQWCLERHGVDVDVSVFDV VANPGQTFRGPDMTIFYSSQLGTYPYYTPTGEP VFGGLPQNASLIAHLARTFQDILAAIPAPDFSG LAVIDWEAWRPRWAFNWDTKDIYRQRSRALVQAQ HPDWPAPQVEAVAQDQFQGAARAWMAGTLQLGR ALRPRGLWGFYGFPDCYNYDFLSPNYTGQCPSG IRAQNDQLGWLWGQSRALYPSIYMPAVLEGTGKS QMYVQHRVAEAFRVAVAAGDPNLPVLPYVQIFY DTTNHFLPLDELEHSLGESAAQGAAGVVLWVSW ENTRTKESCQAIKEYMDTTLGPFILNVTSGALLC SQALCSGHGRCVRRTSHPKALLLLNPASFSIQL TPGGGPLSLRGALSLEDQAQMAVEFKCRCYPGW QAPWCERKSMW*LATH*VAHIENLMHSGSGQGFL KYMHSHTSHGHSKEYTQPLSQAYSLHTHAYLQT GIVA*GVRTTADTIHSMSICIYLARS*TIPPET LSQSLNCSNHKG*HSLSAYSLPIPVLSVLCGLIH SSQ*GYEETESLTLRVSTLPKVAQQEKGEVEIQ TQAV*LRGYSPCTPTEFVVTSPARPLNLLRGTS PANKAVMIYL

Frame 2

MWGAPLPCRPVRDVRSVSPWPPRLRSEEPLRPA AALSEKLVLNS*PQVILPRWPPKVLGLQA*ATT PGPRK*HSLLTTGGKDPRK*SA*GPSMSDAATW TKNTP*AQDTKEPGLQCHKQACPAGSAPAHLLQP RLSSTSPVPWQPTCFPSAPSS*PYSIWPKALGA PCYPTGPSPPSGMQTPSGAWRGTVWTWMSVSSM W*PTQGRPSAALT*QFSIAPSWAPTPTTRPLGSL CLVVCPRMPA*LPTWPAHSRTSWLPYLLLTSQG WQSSTGRHGAHAGPSTGTPRTFTGSAHGHWYRH STLIGQLLRWRQ*PRTSSRELHGPGWQAPSSWGG HCVLAASGASMASLTATTMTF*APTTPASAHQA SVPKMTS*GGCGARAVPSIPASTCPQCWRAQGS HRCMCNTVWPRHSVWLWLLVTPICRCCPMSRSSM TRQTTFCPWMSWSTAWGRVRPRGQLEWCSG*AG KIQEPRNHVRPSRSIWTLHWGPSS*T*PVGPFS AVKPCAPAMAAVSAAPATPKPSSSLTLPVSPSSS RLVVGP*ACGVPSHLKIRHRWLWSSNVDATLAG RHRGVSGRACGDWPHTELHILRT*CTLGLARAS SNTCTVIQVMVTVKSTLSHCHRHIPCTHMHTYRL E*WHKELEPQQTPFIPCPYASTWQGHRQFLQRH *ASL*TAAITKADIH*VPTLCQSPC*AFYVDLF IPHNEAMRKLSHSH*E*ARCPRLHSKKREKLRFK PRLSSSGGTALALLLSLW*PALHDP*IC*EAPV QQIKQS*FT

Sequence NM_007312

CTTCCTCCAGGAGTCTCTGGTGCAGCTGGGGTGGAATCTGGCCAGGCCCTGCTTAGGCCCCCATCCTGGGGTCAGGAAATTTGGAGGATAAGGCCCTTCA GCCCCAAGGTCAGCAGGGACGAGCGGGCAGACTGGCGGGTGTACAGGAGGGCTGGGTTGACCTGTCCTTGGTCACTGAGGCCATTGGATCTTCCTCCAGT GGCTGCCAGGATTTCTGGTGGAAGAGACAGGAAGGCCTCCCCCCCTTGGTCGGGTCAGCCTGGGGGCTGAGGGCCTGGCTGTCAGCCACTCTTCCCAGAA CATATGTCATGGCCTCAGTGGCTCATGGGGAAGCAGGGGTGGGCGAGCTTAGGCTAGAGCAAGTCCTGTGGGAGATGGCAGAGGCCTGGTCTGAGAGGCA ACTCGGATGTGCCCTCCAGTGGCCATGCTCCCCTCCATGCGTCTCCCCTGCCCTCCTGGAGCCCTGCAGGTCAATGTTTAACAGAAACCAGAGCAGCGGT GGATTAATGCGCAAGGGCTCAGCCCCCCAGCCCTGAGCAGTGGGGGAATCGGAGACTTTGCAACCTGTTCTCAGCTCTGCCTCCCCTGGCCAGGTTGTCC TCGACCAGTCCCGTGCCATGGCAGCCCACCTGCTTCCCATCTGCGCCCTCTTCCTGACCTTACTCGATATGGCCCAAGGCTTTAGGGGCCCCTTGCTACC CAACCGGCCCTTCACCACCGTCTGGAATGCAAACACCCAGTGGTGCCTGGAGAGGCACGGTGTGGACGTGGATGTCAGTGTCTTCGATGTGGTAGCCAAC CCAGGGCAGACCTTCCGCGGCCCTGACATGACAATTTTCTATAGCTCCCAGCTGGGCACCTACCCCTACTACACGCCCACTGGGGAGCCTGTGTTTGGTG GTCTGCCCCAGAATGCCAGCCTGATTGCCCACCTGGCCCGCACATTCCAGGACATCCTGGCTGCCATACCTGCTCCTGACTTCTCAGGGCTGGCAGTCAT CGACTGGGAGGCATGGCGCCCACGCTGGGCCTTCAACTGGGACACCAAGGACATTTACCGGCAGCGCTCACGGGCACTGGTACAGGCACAGCACCCTGAT TGGCCAGCTCCTCAGGTGGAGGCAGTAGCCCAGGACCAGTTCCAGGGAGCTGCACGGGCCTGGATGGCAGGCACCCTCCAGCTGGGGCGGGCACTGCGTC CTCGCGGCCTCTGGGGCTTCTATGGCTTCCCTGACTGCTACAACTATGACTTTCTAAGCCCCAACTACACCGGCCAGTGCCCATCAGGCATCCGTGCCCA AAATGACCAGCTAGGGTGGCTGTGGGGCCAGAGCCGTGCCCTCTATCCCAGCATCTACATGCCCGCAGTGCTGGAGGGCACAGGGAAGTCACAGATGTAT GTGCAACACCGTGTGGCCGAGGCATTCCGTGTGGCTGTGGCTGCTGGTGACCCCAATCTGCCGGTGCTGCCCTATGTCCAGATCTTCTATGACACGACAA ACCACTTTCTGCCCCTGGATGAGCTGGAGCACAGCCTGGGGGAGAGTGCGGCCCAGGGGGCAGCTGGAGTGGTGCTCTGGGTGAGCTGGGAAAATACAAG AACCAAGGAATCATGTCAGGCCATCAAGGAGTATATGGACACTACACTGGGGCCCTTCATCCTGAACGTGACCAGTGGGGCCCTTCTCTGCAGTCAAGCC CTGTGCTCCGGCCATGGCCGCTGTGTCCGCCGCACCAGCCACCCCAAAGCCCTCCTCCTCCTTAACCCTGCCAGTTTCTCCATCCAGCTCACGCCTGGTG GTGGGCCCCTGAGCCTGCGGGGTGCCCTCTCACTTGAAGATCAGGCACAGATGGCTGTGGAGTTCAAATGTCGATGCTACCCTGGCTGGCAGGCACCGTG GTGTGAGCGGAAGAGCATGTGGTGATTGGCCACACACTGAGTTGCACATATTGAGAACCTAATGCACTCTGGGTCTGGCCAGGGCTTCCTCAAATACATG CACAGTCATACAAGTCATGGTCACAGTAAAGAGTACACTCAGCCACTGTCACAGGCATATTCCCTGCACACACATGCATACTTACAGACTGGAATAGTGG CATAAGGAGTTAGAACCACAGCAGACACCATTCATTCCATGTCCATATGCATCTACTTGGCAAGGTCATAGACAATTCCTCCAGAGACACTGAGCCAGTC TTTGAACTGCAGCAATCACAAAGGCTGACATTCACTGAGTGCCTACTCTTTGCCAATCCCCGTGCTAAGCGTTTTATGTGGACTTATTCATTCCTCACAA TGAGGCTATGAGGAAACTGAGTCACTCACATTGAGAGTAAGCACGTTGCCCAAGGTTGCACAGCAAGAAAAGGGAGAAGTTGAGATTCAAACCCAGGCTG TCTAGCTCCGGGGGTACAGCCCTTGCACTCCTACTGAGTTTGTGGTAACCAGCCCTGCACGACCCCTGAATCTGCTGAGAGGCACCAGTCCAGCAAATAA AGCAGTCATGATTTACTTA

refseq_HYAL1.F1 (forward primer)
refseq_HYAL1.R1 (reverse primer)
Single exon skipping

Frame 0

LPPGVSGAAGVESGQALLRPPSWGQEIWRIRPF SPKVSRDERADWRVYRRAGLTCPWSLRPLDLPPV AARISGGRDRKASPPWSGQPGG*GPGCQPLFPE HMSWPQWLMGKQGWASLG*SKSCGRWQRPGLRG NSDVPSSGHAPLHASPLPSWSPAGQCLTETRAAV D*CARAQPPSPEQWGNRRLCNLFSALPPLARLS STSPVPWQPTCFPSAPSS*PYSIWPKALGAPCY PTGPSPPSGMQTPSGAWRGTVWTWMSVSSMW*PT QGRPSAALT*QFSIAPSWAPTPTTRPLGSLCLV VCPRMPA*LPTWPAHSRTSWLPYLLLTSQGWQS STGRHGAHAGPSTGTPRTFTGSAHGHWYRHSTLI GQLLRWRQ*PRTSSRELHGPGWQAPSSWGGHCV LAASGASMASLTATTMTF*APTTPASAHQASVP KMTS*GGCGARAVPSIPASTCPQCWRAQGSHRCM CNTVWPRHSVWLWLLVTPICRCCPMSRSSMTRQ TTFCPWMSWSTAWGRVRPRGQLEWCSG*AGKIQ EPRNHVRPSRSIWTLHWGPSS*T*PVGPFSAVKP CAPAMAAVSAAPATPKPSSSLTLPVSPSSSRLV VGP*ACGVPSHLKIRHRWLWSSNVDATLAGRHR GVSGRACGDWPHTELHILRT*CTLGLARASSNTC TVIQVMVTVKSTLSHCHRHIPCTHMHTYRLE*W HKELEPQQTPFIPCPYASTWQGHRQFLQRH*AS L*TAAITKADIH*VPTLCQSPC*AFYVDLFIPHN EAMRKLSHSH*E*ARCPRLHSKKREKLRFKPRL SSSGGTALALLLSLW*PALHDP*IC*EAPVQQI KQS*FT

Frame 1

FLQESLVQLGWNLARPCLGPHPGVRKFGG*GPS APRSAGTSGQTGGCTGGLG*PVLGH*GHWIFLQ WLPGFLVEETGRPPPLGRVSLGAEGLAVSHSSQN ICHGLSGSWGSRGGRA*ARASPVGDGRGLV*EA TRMCPPVAMLPSMRLPCPPGALQVNV*QKPEQR WINAQGLSPPALSSGGIGDFATCSQLCLPWPGCP RPVPCHGSPPASHLRPLPDLTRYGPRL*GPLAT QPALHHRLECKHPVVPGEARCGRGCQCLRCGSQ PRADLPRP*HDNFL*LPAGHLPLLHAHWGACVWW SAPECQPDCPPGPHIPGHPGCHTCS*LLRAGSH RLGGMAPTLGLQLGHQGHLPAALTGTGTGTAP* LASSSGGGSSPGPVPGSCTGLDGRHPPAGAGTAS SRPLGLLWLP*LLQL*LSKPQLHRPVPIRHPCP K*PARVAVGPEPCPLSQHLHARSAGGHREVTDV CATPCGRGIPCGCGCW*PQSAGAALCPDLL*HDK PLSAPG*AGAQPGGECGPGGSWSGALGELGKYK NQGIMSGHQGVYGHYTGALHPERDQWGPSLQSS PVLRPWPLCPPHQPPQSPPPP*PCQFLHPAHAWW WAPEPAGCPLT*RSGTDGCGVQMSMLPWLAGTV V*AEEHVVIGHTLSCTY*EPNALWVWPGLPQIH AQSYKSWSQ*RVHSATVTGIFPAHTCILTDWNSG IRS*NHSRHHSFHVHMHLLGKVIDNSSRDTEPV FELQQSQRLTFTECLLFANPRAKRFMWTYSFLT MRL*GN*VTHIESKHVAQGCTARKGRS*DSNPGC LAPGVQPLHSY*VCGNQPCTTPESAERHQSSK* SSHDLL

Frame 2

SSRSLWCSWGGIWPGPA*APILGSGNLEDKALQ PQGQQGRAGRLAGVQEGWVDLSLVTEAIGSSSS GCQDFWWKRQEGLPPLVGSAWGLRAWLSATLPR TYVMASVAHGEAGVGELRLEQVLWEMAEAWSERQ LGCALQWPCSPPCVSPALLEPCRSMFNRNQSSG GLMRKGSAPQP*AVGESETLQPVLSSASPGQVV LDQSRAMAAHLLPICALFLTLLDMAQGFRGPLLP NRPFTTVWNANTQWCLERHGVDVDVSVFDVVAN PGQTFRGPDMTIFYSSQLGTYPYYTPTGEPVFG GLPQNASLIAHLARTFQDILAAIPAPDFSGLAVI DWEAWRPRWAFNWDTKDIYRQRSRALVQAQHPD WPAPQVEAVAQDQFQGAARAWMAGTLQLGRALR PRGLWGFYGFPDCYNYDFLSPNYTGQCPSGIRAQ NDQLGWLWGQSRALYPSIYMPAVLEGTGKSQMY VQHRVAEAFRVAVAAGDPNLPVLPYVQIFYDTT NHFLPLDELEHSLGESAAQGAAGVVLWVSWENTR TKESCQAIKEYMDTTLGPFILNVTSGALLCSQA LCSGHGRCVRRTSHPKALLLLNPASFSIQLTPG GGPLSLRGALSLEDQAQMAVEFKCRCYPGWQAPW CERKSMW*LATH*VAHIENLMHSGSGQGFLKYM HSHTSHGHSKEYTQPLSQAYSLHTHAYLQTGIV A*GVRTTADTIHSMSICIYLARS*TIPPETLSQS LNCSNHKG*HSLSAYSLPIPVLSVLCGLIHSSQ *GYEETESLTLRVSTLPKVAQQEKGEVEIQTQA V*LRGYSPCTPTEFVVTSPARPLNLLRGTSPANK AVMIYL

Sequence NM_153285

CTTCCTCCAGGAGTCTCTGGTGCAGCTGGGGTGGAATCTGGCCAGGCCCTGCTTAGGCCCCCATCCTGGGGTCAGGAAATTTGGAGGATAAGGCCCTTCA GCCCCAAGTGCTGGAGGGCACAGGGAAGTCACAGATGTATGTGCAACACCGTGTGGCCGAGGCATTCCGTGTGGCTGTGGCTGCTGGTGACCCCAATCTG CCGGTGCTGCCCTATGTCCAGATCTTCTATGACACGACAAACCACTTTCTGCCCCTGGATGAGCTGGAGCACAGCCTGGGGGAGAGTGCGGCCCAGGGGG CAGCTGGAGTGGTGCTCTGGGTGAGCTGGGAAAATACAAGAACCAAGGAATCATGTCAGGCCATCAAGGAGTATATGGACACTACACTGGGGCCCTTCAT CCTGAACGTGACCAGTGGGGCCCTTCTCTGCAGTCAAGCCCTGTGCTCCGGCCATGGCCGCTGTGTCCGCCGCACCAGCCACCCCAAAGCCCTCCTCCTC CTTAACCCTGCCAGTTTCTCCATCCAGCTCACGCCTGGTGGTGGGCCCCTGAGCCTGCGGGGTGCCCTCTCACTTGAAGATCAGGCACAGATGGCTGTGG AGTTCAAATGTCGATGCTACCCTGGCTGGCAGGCACCGTGGTGTGAGCGGAAGAGCATGTGGTGATTGGCCACACACTGAGTTGCACATATTGAGAACCT AATGCACTCTGGGTCTGGCCAGGGCTTCCTCAAATACATGCACAGTCATACAAGTCATGGTCACAGTAAAGAGTACACTCAGCCACTGTCACAGGCATAT TCCCTGCACACACATGCATACTTACAGACTGGAATAGTGGCATAAGGAGTTAGAACCACAGCAGACACCATTCATTCCATGTCCATATGCATCTACTTGG CAAGGTCATAGACAATTCCTCCAGAGACACTGAGCCAGTCTTTGAACTGCAGCAATCACAAAGGCTGACATTCACTGAGTGCCTACTCTTTGCCAATCCC CGTGCTAAGCGTTTTATGTGGACTTATTCATTCCTCACAATGAGGCTATGAGGAAACTGAGTCACTCACATTGAGAGTAAGCACGTTGCCCAAGGTTGCA CAGCAAGAAAAGGGAGAAGTTGAGATTCAAACCCAGGCTGTCTAGCTCCGGGGGTACAGCCCTTGCACTCCTACTGAGTTTGTGGTAACCAGCCCTGCAC GACCCCTGAATCTGCTGAGAGGCACCAGTCCAGCAAATAAAGCAGTCATGATTTACTTA

refseq_HYAL1.F1 (forward primer)
refseq_HYAL1.R1 (reverse primer)
Single exon skipping

Frame 0

LPPGVSGAAGVESGQALLRPPSWGQEIWRIRPF SPKCWRAQGSHRCMCNTVWPRHSVWLWLLVTPIC RCCPMSRSSMTRQTTFCPWMSWSTAWGRVRPRG QLEWCSG*AGKIQEPRNHVRPSRSIWTLHWGPS S*T*PVGPFSAVKPCAPAMAAVSAAPATPKPSSS LTLPVSPSSSRLVVGP*ACGVPSHLKIRHRWLW SSNVDATLAGRHRGVSGRACGDWPHTELHILRT *CTLGLARASSNTCTVIQVMVTVKSTLSHCHRHI PCTHMHTYRLE*WHKELEPQQTPFIPCPYASTW QGHRQFLQRH*ASL*TAAITKADIH*VPTLCQS PC*AFYVDLFIPHNEAMRKLSHSH*E*ARCPRLH SKKREKLRFKPRLSSSGGTALALLLSLW*PALH DP*IC*EAPVQQIKQS*FT

Frame 1

FLQESLVQLGWNLARPCLGPHPGVRKFGG*GPS APSAGGHREVTDVCATPCGRGIPCGCGCW*PQS AGAALCPDLL*HDKPLSAPG*AGAQPGGECGPGG SWSGALGELGKYKNQGIMSGHQGVYGHYTGALH PERDQWGPSLQSSPVLRPWPLCPPHQPPQSPPP P*PCQFLHPAHAWWWAPEPAGCPLT*RSGTDGCG VQMSMLPWLAGTVV*AEEHVVIGHTLSCTY*EP NALWVWPGLPQIHAQSYKSWSQ*RVHSATVTGI FPAHTCILTDWNSGIRS*NHSRHHSFHVHMHLLG KVIDNSSRDTEPVFELQQSQRLTFTECLLFANP RAKRFMWTYSFLTMRL*GN*VTHIESKHVAQGC TARKGRS*DSNPGCLAPGVQPLHSY*VCGNQPCT TPESAERHQSSK*SSHDLL

Frame 2

SSRSLWCSWGGIWPGPA*APILGSGNLEDKALQ PQVLEGTGKSQMYVQHRVAEAFRVAVAAGDPNL PVLPYVQIFYDTTNHFLPLDELEHSLGESAAQG AAGVVLWVSWENTRTKESCQAIKEYMDTTLGPFI LNVTSGALLCSQALCSGHGRCVRRTSHPKALLL LNPASFSIQLTPGGGPLSLRGALSLEDQAQMAV EFKCRCYPGWQAPWCERKSMW*LATH*VAHIENL MHSGSGQGFLKYMHSHTSHGHSKEYTQPLSQAY SLHTHAYLQTGIVA*GVRTTADTIHSMSICIYL ARS*TIPPETLSQSLNCSNHKG*HSLSAYSLPIP VLSVLCGLIHSSQ*GYEETESLTLRVSTLPKVA QQEKGEVEIQTQAV*LRGYSPCTPTEFVVTSPA RPLNLLRGTSPANKAVMIYL

Sequence NM_033159

CTTCCTCCAGGAGTCTCTGGTGCAGCTGGGGTGGAATCTGGCCAGGCCCTGCTTAGGCCCCCATCCTGGGGTCAGGAAATTTGGAGGATAAGGCCCTTCA GCCCCAAGGTTGTCCTCGACCAGTCCCGTGCCATGGCAGCCCACCTGCTTCCCATCTGCGCCCTCTTCCTGACCTTACTCGATATGGCCCAAGGCTTTAG GGGCCCCTTGCTACCCAACCGGCCCTTCACCACCGTCTGGAATGCAAACACCCAGTGGTGCCTGGAGAGGCACGGTGTGGACGTGGATGTCAGTGTCTTC GATGTGGTAGCCAACCCAGGGCAGACCTTCCGCGGCCCTGACATGACAATTTTCTATAGCTCCCAGCTGGGCACCTACCCCTACTACACGCCCACTGGGG AGCCTGTGTTTGGTGGTCTGCCCCAGAATGCCAGCCTGATTGCCCACCTGGCCCGCACATTCCAGGACATCCTGGCTGCCATACCTGCTCCTGACTTCTC AGGGCTGGCAGTCATCGACTGGGAGGCATGGCGCCCACGCTGGGCCTTCAACTGGGACACCAAGGACATTTACCGGCAGCGCTCACGGGCACTGGTACAG GCACAGCACCCTGATTGGCCAGCTCCTCAGGTGGAGGCAGTAGCCCAGGACCAGTTCCAGGGAGCTGCACGGGCCTGGATGGCAGGCACCCTCCAGCTGG GGCGGGCACTGCGTCCTCGCGGCCTCTGGGGCTTCTATGGCTTCCCTGACTGCTACAACTATGACTTTCTAAGCCCCAACTACACCGGCCAGTGCCCATC AGGCATCCGTGCCCAAAATGACCAGCTAGGGTGGCTGTGGGGCCAGAGCCGTGCCCTCTATCCCAGCATCTACATGCCCGCAGTGCTGGAGGGCACAGGG AAGTCACAGATGTATGTGCAACACCGTGTGGCCGAGGCATTCCGTGTGGCTGTGGCTGCTGGTGACCCCAATCTGCCGGTGCTGCCCTATGTCCAGATCT TCTATGACACGACAAACCACTTTCTGCCCCTGGATGAGCTGGAGCACAGCCTGGGGGAGAGTGCGGCCCAGGGGGCAGCTGGAGTGGTGCTCTGGGTGAG CTGGGAAAATACAAGAACCAAGGAATCATGTCAGGCCATCAAGGAGTATATGGACACTACACTGGGGCCCTTCATCCTGAACGTGACCAGTGGGGCCCTT CTCTGCAGTCAAGCCCTGTGCTCCGGCCATGGCCGCTGTGTCCGCCGCACCAGCCACCCCAAAGCCCTCCTCCTCCTTAACCCTGCCAGTTTCTCCATCC AGCTCACGCCTGGTGGTGGGCCCCTGAGCCTGCGGGGTGCCCTCTCACTTGAAGATCAGGCACAGATGGCTGTGGAGTTCAAATGTCGATGCTACCCTGG CTGGCAGGCACCGTGGTGTGAGCGGAAGAGCATGTGGTGATTGGCCACACACTGAGTTGCACATATTGAGAACCTAATGCACTCTGGGTCTGGCCAGGGC TTCCTCAAATACATGCACAGTCATACAAGTCATGGTCACAGTAAAGAGTACACTCAGCCACTGTCACAGGCATATTCCCTGCACACACATGCATACTTAC AGACTGGAATAGTGGCATAAGGAGTTAGAACCACAGCAGACACCATTCATTCCATGTCCATATGCATCTACTTGGCAAGGTCATAGACAATTCCTCCAGA GACACTGAGCCAGTCTTTGAACTGCAGCAATCACAAAGGCTGACATTCACTGAGTGCCTACTCTTTGCCAATCCCCGTGCTAAGCGTTTTATGTGGACTT ATTCATTCCTCACAATGAGGCTATGAGGAAACTGAGTCACTCACATTGAGAGTAAGCACGTTGCCCAAGGTTGCACAGCAAGAAAAGGGAGAAGTTGAGA TTCAAACCCAGGCTGTCTAGCTCCGGGGGTACAGCCCTTGCACTCCTACTGAGTTTGTGGTAACCAGCCCTGCACGACCCCTGAATCTGCTGAGAGGCAC CAGTCCAGCAAATAAAGCAGTCATGATTTACTTA

refseq_HYAL1.F1 (forward primer)
refseq_HYAL1.R1 (reverse primer)
Single exon skipping

Frame 0

LPPGVSGAAGVESGQALLRPPSWGQEIWRIRPF SPKVVLDQSRAMAAHLLPICALFLTLLDMAQGFR GPLLPNRPFTTVWNANTQWCLERHGVDVDVSVF DVVANPGQTFRGPDMTIFYSSQLGTYPYYTPTG EPVFGGLPQNASLIAHLARTFQDILAAIPAPDFS GLAVIDWEAWRPRWAFNWDTKDIYRQRSRALVQ AQHPDWPAPQVEAVAQDQFQGAARAWMAGTLQL GRALRPRGLWGFYGFPDCYNYDFLSPNYTGQCPS GIRAQNDQLGWLWGQSRALYPSIYMPAVLEGTG KSQMYVQHRVAEAFRVAVAAGDPNLPVLPYVQI FYDTTNHFLPLDELEHSLGESAAQGAAGVVLWVS WENTRTKESCQAIKEYMDTTLGPFILNVTSGAL LCSQALCSGHGRCVRRTSHPKALLLLNPASFSI QLTPGGGPLSLRGALSLEDQAQMAVEFKCRCYPG WQAPWCERKSMW*LATH*VAHIENLMHSGSGQG FLKYMHSHTSHGHSKEYTQPLSQAYSLHTHAYL QTGIVA*GVRTTADTIHSMSICIYLARS*TIPPE TLSQSLNCSNHKG*HSLSAYSLPIPVLSVLCGL IHSSQ*GYEETESLTLRVSTLPKVAQQEKGEVE IQTQAV*LRGYSPCTPTEFVVTSPARPLNLLRGT SPANKAVMIYL

Frame 1

FLQESLVQLGWNLARPCLGPHPGVRKFGG*GPS APRLSSTSPVPWQPTCFPSAPSS*PYSIWPKAL GAPCYPTGPSPPSGMQTPSGAWRGTVWTWMSVSS MW*PTQGRPSAALT*QFSIAPSWAPTPTTRPLG SLCLVVCPRMPA*LPTWPAHSRTSWLPYLLLTS QGWQSSTGRHGAHAGPSTGTPRTFTGSAHGHWYR HSTLIGQLLRWRQ*PRTSSRELHGPGWQAPSSW GGHCVLAASGASMASLTATTMTF*APTTPASAH QASVPKMTS*GGCGARAVPSIPASTCPQCWRAQG SHRCMCNTVWPRHSVWLWLLVTPICRCCPMSRS SMTRQTTFCPWMSWSTAWGRVRPRGQLEWCSG* AGKIQEPRNHVRPSRSIWTLHWGPSS*T*PVGPF SAVKPCAPAMAAVSAAPATPKPSSSLTLPVSPS SSRLVVGP*ACGVPSHLKIRHRWLWSSNVDATL AGRHRGVSGRACGDWPHTELHILRT*CTLGLARA SSNTCTVIQVMVTVKSTLSHCHRHIPCTHMHTY RLE*WHKELEPQQTPFIPCPYASTWQGHRQFLQ RH*ASL*TAAITKADIH*VPTLCQSPC*AFYVDL FIPHNEAMRKLSHSH*E*ARCPRLHSKKREKLR FKPRLSSSGGTALALLLSLW*PALHDP*IC*EA PVQQIKQS*FT

Frame 2

SSRSLWCSWGGIWPGPA*APILGSGNLEDKALQ PQGCPRPVPCHGSPPASHLRPLPDLTRYGPRL* GPLATQPALHHRLECKHPVVPGEARCGRGCQCL RCGSQPRADLPRP*HDNFL*LPAGHLPLLHAHWG ACVWWSAPECQPDCPPGPHIPGHPGCHTCS*LL RAGSHRLGGMAPTLGLQLGHQGHLPAALTGTGT GTAP*LASSSGGGSSPGPVPGSCTGLDGRHPPAG AGTASSRPLGLLWLP*LLQL*LSKPQLHRPVPI RHPCPK*PARVAVGPEPCPLSQHLHARSAGGHR EVTDVCATPCGRGIPCGCGCW*PQSAGAALCPDL L*HDKPLSAPG*AGAQPGGECGPGGSWSGALGE LGKYKNQGIMSGHQGVYGHYTGALHPERDQWGP SLQSSPVLRPWPLCPPHQPPQSPPPP*PCQFLHP AHAWWWAPEPAGCPLT*RSGTDGCGVQMSMLPW LAGTVV*AEEHVVIGHTLSCTY*EPNALWVWPG LPQIHAQSYKSWSQ*RVHSATVTGIFPAHTCILT DWNSGIRS*NHSRHHSFHVHMHLLGKVIDNSSR DTEPVFELQQSQRLTFTECLLFANPRAKRFMWT YSFLTMRL*GN*VTHIESKHVAQGCTARKGRS*D SNPGCLAPGVQPLHSY*VCGNQPCTTPESAERH QSSK*SSHDLL