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Sequences

Sequence NM_201536

CGGCCCCCCGCATTCCCCGCCCCCACCTCCCCGCCTTGTTGTCCAACTTCTCCCGGAGCAGCCGGAGAGCAGGCGTCGGGACGCAGCAAAGAGAGGAGAG GCCACCATGGCGGAGCTGCAGGAGGTGCAGATCACAGAGGAGAAGCCACTGTTGCCAGGACAGACGCCTGAGGCGGCCAAGACTCACTCTGTGGAGACAC CATACGGCTCTGTCACTTTCACTGTCTATGGCACCCCCAAACCCAAACGCCCAGCGATCCTTACCTACCACGATGTGGGACTCAACTATAAATCTTGCTT CCAGCCACTGTTTCAGTTCGAGGACATGCAGGAAATCATTCAGAACTTTGTGCGGGTTCATGTGGATGCCCCTGGAATGGAAGAGGGAGCCCCTGTGTTC CCTTTGGGATATCAGTACCCATCTCTGGACCAGCTTGCAGACATGATCCCTTGCGTCCTGCAGTACCTAAATTTCTCTACAATAATTGGAGTTGGTGTTG GAGCTGGAGCCTACATCCTGGCGAGATATGCTCTTAACCACCCGGACACTGTTGAAGGTCTTGTCCTCATCAACATTGATCCCAATGCCAAGGGTTGGAT GGATTGGGCAGCCCACAAGCTAACAGGCCTCACCTCTTCCATTCCGGAGATGATCCTTGGACATCTTTTCAGCCAGGAAGAGCTCTCTGGAAATTCTGAG TTGATACAAAAGTACAGAAATATCATTACACATGCACCCAACCTGGATAACATTGAATTGTACTGGAACAGCTACAACAACCGCCGAGACCTGAACTTTG AGCGTGGAGGTGATATCACCCTCAGGTGTCCTGTGATGCTGGTGGTAGGAGACCAAGCACCTCATGAAGATGCAGTGGTGGAATGTAACTCAAAACTGGA CCCCACCCAGACCTCGTTCCTCAAGATGGCTGACTCCGGAGGTCAGCCCCAGCTGACTCAGCCAGGCAAGCTGACCGAGGCCTTCAAGTACTTCCTGCAA GGCATGGGCTACATGGCCTCATCCTGCATGACTCGCCTGTCCCGGTCTCGTACAGCCTCTCTGACCAGTGCAGCATCCGTTGATGGCAACCGGTCCCGCT CTCGCACCCTGTCCCAGAGCAGCGAGTCTGGAACTCTTTCTTCGGGGCCCCCGGGGCACACCATGGAGGTCTCCTGTTGAATGGCCCTTGTTGCCCTAGA GTGGGACCCAGCCCTCACCTCCCCCAGAGCTAACCTGGGAGGTGCTGAAGGGGCATTGGGCCACCGTAAGCAAGGGAAAAAGGGCAGATCATGCGGGGAG ATGACCTTGATCTTTGATTGCTACCCTAACCTTGACCTTTAACCCGTGATTCCCCCCAGCTCCTGGAAGAGATGTCCTAATATCTCTTAGGGACCCAGAC CCCTAAATTCTCCTCCTCCCCCATTTTGATGTTAAGGTGGAGAGGGCATATGCATCCTCTGTCCTGATCTAGGTGTCTATAGCTGAGGGGTAAGAGGTTG TTGTAGTTGTCCTGGTGCCTCCATCAGACTCTCCCTACTTGTCCCATATTTGCAAGGGGAGGGGATTTGGGGCTGGGGCTCCATTCACCAAAGCTGAGGT GGCTTCTCATTAACCCTTTAGGACTCTGAAGGGTATGGACCTACGTGAATGTGTGTCAGGGGGAGACTTGCTGGTGGGTTAGTGGTCCTCAGGATGTGAT AGAAACATCCAGTGTAAAAAGGAAGTTGGAATGGGAGTTGGCGGGCAGTGAACGAGTGTGGGGAAGGATTGGTGCTGGGGCAACAGGAAGGGGCCTGGGG CCGTTTGGCTGCACTAACTTTGGTAGCTCAGTGTGCATCTAGAGTGGGACTGGGGAGGGAGCTAAGCTTGGGCTGGGCTGCTTGGGGCTTGGCATAGGGT GGAAAGGGCTACCCTGGGGCTCTGACCACACTGTAGTATGTGTGGAGGGTGCCCTCCCGTCTCCCACAACTTCTGCTATAACAATAAACTGTAGAGGAAT CTGAGTACCGTTA

refseq_NDRG2.F5 (forward primer)
refseq_NDRG2.R3 (reverse primer)
Single exon skipping

Frame 0

RPPAFPAPTSPPCCPTSPGAAGEQASGRSKERR GHHGGAAGGADHRGEATVARTDA*GGQDSLCGDT IRLCHFHCLWHPQTQTPSDPYLPRCGTQL*ILL PATVSVRGHAGNHSELCAGSCGCPWNGRGSPCV PFGISVPISGPACRHDPLRPAVPKFLYNNWSWCW SWSLHPGEICS*PPGHC*RSCPHQH*SQCQGLD GLGSPQANRPHLFHSGDDPWTSFQPGRALWKF* VDTKVQKYHYTCTQPG*H*IVLEQLQQPPRPEL* AWR*YHPQVSCDAGGRRPSTS*RCSGGM*LKTG PHPDLVPQDG*LRRSAPADSARQADRGLQVLPA RHGLHGLILHDSPVPVSYSLSDQCSIR*WQPVPL SHPVPEQRVWNSFFGAPGAHHGGLLLNGPCCPR VGPSPHLPQS*PGRC*RGIGPP*AREKGQIMRG DDLDL*LLP*P*PLTRDSPQLLEEMS*YLLGTQT PKFSSSPILMLRWRGHMHPLS*SRCL*LRGKRL L*LSWCLHQTLPTCPIFARGGDLGLGLHSPKLR WLLINPLGL*RVWTYVNVCQGETCWWVSGPQDVI ETSSVKRKLEWELAGSERVWGRIGAGATGRGLG PFGCTNFGSSVCI*SGTGEGAKLGLGCLGLGIG WKGLPWGSDHTVVCVEGALPSPTTSAITINCRGI *VPL

Frame 1

GPPHSPPPPPRLVVQLLPEQPESRRRDAAKRGE ATMAELQEVQITEEKPLLPGQTPEAAKTHSVET PYGSVTFTVYGTPKPKRPAILTYHDVGLNYKSCF QPLFQFEDMQEIIQNFVRVHVDAPGMEEGAPVF PLGYQYPSLDQLADMIPCVLQYLNFSTIIGVGV GAGAYILARYALNHPDTVEGLVLINIDPNAKGWM DWAAHKLTGLTSSIPEMILGHLFSQEELSGNSE LIQKYRNIITHAPNLDNIELYWNSYNNRRDLNF ERGGDITLRCPVMLVVGDQAPHEDAVVECNSKLD PTQTSFLKMADSGGQPQLTQPGKLTEAFKYFLQ GMGYMASSCMTRLSRSRTASLTSAASVDGNRSR SRTLSQSSESGTLSSGPPGHTMEVSC*MALVALE WDPALTSPRANLGGAEGALGHRKQGKKGRSCGE MTLIFDCYPNLDL*PVIPPSSWKRCPNIS*GPR PLNSPPPPF*C*GGEGICILCPDLGVYS*GVRGC CSCPGASIRLSLLVPYLQGEGIWGWGSIHQS*G GFSLTL*DSEGYGPT*MCVRGRLAGGLVVLRM* *KHPV*KGSWNGSWRAVNECGEGLVLGQQEGAWG RLAALTLVAQCASRVGLGRELSLGWAAWGLA*G GKGYPGALTTL*YVWRVPSRLPQLLL*Q*TVEE SEYR

Frame 2

APRIPRPHLPALLSNFSRSSRRAGVGTQQREER PPWRSCRRCRSQRRSHCCQDRRLRRPRLTLWRH HTALSLSLSMAPPNPNAQRSLPTTMWDSTINLA SSHCFSSRTCRKSFRTLCGFMWMPLEWKREPLCS LWDISTHLWTSLQT*SLASCST*ISLQ*LELVL ELEPTSWRDMLLTTRTLLKVLSSSTLIPMPRVG WIGQPTS*QASPLPFRR*SLDIFSARKSSLEILS *YKSTEISLHMHPTWITLNCTGTATTTAET*TL SVEVISPSGVL*CWW*ETKHLMKMQWWNVTQNW TPPRPRSSRWLTPEVSPS*LSQAS*PRPSSTSCK AWATWPHPA*LACPGLVQPL*PVQHPLMATGPA LAPCPRAASLELFLRGPRGTPWRSPVEWPLLP* SGTQPSPPPELTWEVLKGHWATVSKGKRADHAGR *P*SLIATLTLTFNP*FPPAPGRDVLISLRDPD P*ILLLPHFDVKVERAYASSVLI*VSIAEG*EV VVVVLVPPSDSPYLSHICKGRGFGAGAPFTKAEV ASH*PFRTLKGMDLRECVSGGDLLVG*WSSGCD RNIQCKKEVGMGVGGQ*TSVGKDWCWGNRKGPG AVWLH*LW*LSVHLEWDWGGS*AWAGLLGAWHRV ERATLGL*PHCSMCGGCPPVSHNFCYNNKL*RN LSTV

Sequence NM_201537

CGGCCCCCCGCATTCCCCGCCCCCACCTCCCCGCCTTGTTGTCCAACTTCTCCCGGAGCAGCCGGAGAGCAGGCGTCGGGACGCAGCAAAGAGAGGAGAG GCCACCATGGCGGAGCTGCAGGAGGTGCAGATCACAGAGGAGAAGCCACTGTTGCCAGGACAGACGCCTGAGGCGGCCAAGGAGGCTGAGTTAGCTGCCC GAATCCTCCTGGACCAGGGACAGACTCACTCTGTGGAGACACCATACGGCTCTGTCACTTTCACTGTCTATGGCACCCCCAAACCCAAACGCCCAGCGAT CCTTACCTACCACGATGTGGGACTCAACTATAAATCTTGCTTCCAGCCACTGTTTCAGTTCGAGGACATGCAGGAAATCATTCAGAACTTTGTGCGGGTT CATGTGGATGCCCCTGGAATGGAAGAGGGAGCCCCTGTGTTCCCTTTGGGATATCAGTACCCATCTCTGGACCAGCTTGCAGACATGATCCCTTGCGTCC TGCAGTACCTAAATTTCTCTACAATAATTGGAGTTGGTGTTGGAGCTGGAGCCTACATCCTGGCGAGATATGCTCTTAACCACCCGGACACTGTTGAAGG TCTTGTCCTCATCAACATTGATCCCAATGCCAAGGGTTGGATGGATTGGGCAGCCCACAAGCTAACAGGCCTCACCTCTTCCATTCCGGAGATGATCCTT GGACATCTTTTCAGCCAGGAAGAGCTCTCTGGAAATTCTGAGTTGATACAAAAGTACAGAAATATCATTACACATGCACCCAACCTGGATAACATTGAAT TGTACTGGAACAGCTACAACAACCGCCGAGACCTGAACTTTGAGCGTGGAGGTGATATCACCCTCAGGTGTCCTGTGATGCTGGTGGTAGGAGACCAAGC ACCTCATGAAGATGCAGTGGTGGAATGTAACTCAAAACTGGACCCCACCCAGACCTCGTTCCTCAAGATGGCTGACTCCGGAGGTCAGCCCCAGCTGACT CAGCCAGGCAAGCTGACCGAGGCCTTCAAGTACTTCCTGCAAGGCATGGGCTACATGGCCTCATCCTGCATGACTCGCCTGTCCCGGTCTCGTACAGCCT CTCTGACCAGTGCAGCATCCGTTGATGGCAACCGGTCCCGCTCTCGCACCCTGTCCCAGAGCAGCGAGTCTGGAACTCTTTCTTCGGGGCCCCCGGGGCA CACCATGGAGGTCTCCTGTTGAATGGCCCTTGTTGCCCTAGAGTGGGACCCAGCCCTCACCTCCCCCAGAGCTAACCTGGGAGGTGCTGAAGGGGCATTG GGCCACCGTAAGCAAGGGAAAAAGGGCAGATCATGCGGGGAGATGACCTTGATCTTTGATTGCTACCCTAACCTTGACCTTTAACCCGTGATTCCCCCCA GCTCCTGGAAGAGATGTCCTAATATCTCTTAGGGACCCAGACCCCTAAATTCTCCTCCTCCCCCATTTTGATGTTAAGGTGGAGAGGGCATATGCATCCT CTGTCCTGATCTAGGTGTCTATAGCTGAGGGGTAAGAGGTTGTTGTAGTTGTCCTGGTGCCTCCATCAGACTCTCCCTACTTGTCCCATATTTGCAAGGG GAGGGGATTTGGGGCTGGGGCTCCATTCACCAAAGCTGAGGTGGCTTCTCATTAACCCTTTAGGACTCTGAAGGGTATGGACCTACGTGAATGTGTGTCA GGGGGAGACTTGCTGGTGGGTTAGTGGTCCTCAGGATGTGATAGAAACATCCAGTGTAAAAAGGAAGTTGGAATGGGAGTTGGCGGGCAGTGAACGAGTG TGGGGAAGGATTGGTGCTGGGGCAACAGGAAGGGGCCTGGGGCCGTTTGGCTGCACTAACTTTGGTAGCTCAGTGTGCATCTAGAGTGGGACTGGGGAGG GAGCTAAGCTTGGGCTGGGCTGCTTGGGGCTTGGCATAGGGTGGAAAGGGCTACCCTGGGGCTCTGACCACACTGTAGTATGTGTGGAGGGTGCCCTCCC GTCTCCCACAACTTCTGCTATAACAATAAACTGTAGAGGAATCTGAGTACCGTTA

refseq_NDRG2.F5 (forward primer)
refseq_NDRG2.R3 (reverse primer)
Single exon skipping

Frame 0

RPPAFPAPTSPPCCPTSPGAAGEQASGRSKERR GHHGGAAGGADHRGEATVARTDA*GGQGG*VSCP NPPGPGTDSLCGDTIRLCHFHCLWHPQTQTPSD PYLPRCGTQL*ILLPATVSVRGHAGNHSELCAG SCGCPWNGRGSPCVPFGISVPISGPACRHDPLRP AVPKFLYNNWSWCWSWSLHPGEICS*PPGHC*R SCPHQH*SQCQGLDGLGSPQANRPHLFHSGDDP WTSFQPGRALWKF*VDTKVQKYHYTCTQPG*H*I VLEQLQQPPRPEL*AWR*YHPQVSCDAGGRRPS TS*RCSGGM*LKTGPHPDLVPQDG*LRRSAPAD SARQADRGLQVLPARHGLHGLILHDSPVPVSYSL SDQCSIR*WQPVPLSHPVPEQRVWNSFFGAPGA HHGGLLLNGPCCPRVGPSPHLPQS*PGRC*RGI GPP*AREKGQIMRGDDLDL*LLP*P*PLTRDSPQ LLEEMS*YLLGTQTPKFSSSPILMLRWRGHMHP LS*SRCL*LRGKRLL*LSWCLHQTLPTCPIFAR GGDLGLGLHSPKLRWLLINPLGL*RVWTYVNVCQ GETCWWVSGPQDVIETSSVKRKLEWELAGSERV WGRIGAGATGRGLGPFGCTNFGSSVCI*SGTGE GAKLGLGCLGLGIGWKGLPWGSDHTVVCVEGALP SPTTSAITINCRGI*VPL

Frame 1

GPPHSPPPPPRLVVQLLPEQPESRRRDAAKRGE ATMAELQEVQITEEKPLLPGQTPEAAKEAELAA RILLDQGQTHSVETPYGSVTFTVYGTPKPKRPAI LTYHDVGLNYKSCFQPLFQFEDMQEIIQNFVRV HVDAPGMEEGAPVFPLGYQYPSLDQLADMIPCV LQYLNFSTIIGVGVGAGAYILARYALNHPDTVEG LVLINIDPNAKGWMDWAAHKLTGLTSSIPEMIL GHLFSQEELSGNSELIQKYRNIITHAPNLDNIE LYWNSYNNRRDLNFERGGDITLRCPVMLVVGDQA PHEDAVVECNSKLDPTQTSFLKMADSGGQPQLT QPGKLTEAFKYFLQGMGYMASSCMTRLSRSRTA SLTSAASVDGNRSRSRTLSQSSESGTLSSGPPGH TMEVSC*MALVALEWDPALTSPRANLGGAEGAL GHRKQGKKGRSCGEMTLIFDCYPNLDL*PVIPP SSWKRCPNIS*GPRPLNSPPPPF*C*GGEGICIL CPDLGVYS*GVRGCCSCPGASIRLSLLVPYLQG EGIWGWGSIHQS*GGFSLTL*DSEGYGPT*MCV RGRLAGGLVVLRM**KHPV*KGSWNGSWRAVNEC GEGLVLGQQEGAWGRLAALTLVAQCASRVGLGR ELSLGWAAWGLA*GGKGYPGALTTL*YVWRVPS RLPQLLL*Q*TVEESEYR

Frame 2

APRIPRPHLPALLSNFSRSSRRAGVGTQQREER PPWRSCRRCRSQRRSHCCQDRRLRRPRRLS*LP ESSWTRDRLTLWRHHTALSLSLSMAPPNPNAQR SLPTTMWDSTINLASSHCFSSRTCRKSFRTLCGF MWMPLEWKREPLCSLWDISTHLWTSLQT*SLAS CST*ISLQ*LELVLELEPTSWRDMLLTTRTLLK VLSSSTLIPMPRVGWIGQPTS*QASPLPFRR*SL DIFSARKSSLEILS*YKSTEISLHMHPTWITLN CTGTATTTAET*TLSVEVISPSGVL*CWW*ETK HLMKMQWWNVTQNWTPPRPRSSRWLTPEVSPS*L SQAS*PRPSSTSCKAWATWPHPA*LACPGLVQP L*PVQHPLMATGPALAPCPRAASLELFLRGPRG TPWRSPVEWPLLP*SGTQPSPPPELTWEVLKGHW ATVSKGKRADHAGR*P*SLIATLTLTFNP*FPP APGRDVLISLRDPDP*ILLLPHFDVKVERAYAS SVLI*VSIAEG*EVVVVVLVPPSDSPYLSHICKG RGFGAGAPFTKAEVASH*PFRTLKGMDLRECVS GGDLLVG*WSSGCDRNIQCKKEVGMGVGGQ*TS VGKDWCWGNRKGPGAVWLH*LW*LSVHLEWDWGG S*AWAGLLGAWHRVERATLGL*PHCSMCGGCPP VSHNFCYNNKL*RNLSTV

Sequence NM_016250

CGGCCCCCCGCATTCCCCGCCCCCACCTCCCCGCCTTGTTGTCCAACTTCTCCCGGAGCAGCCGGAGAGCAGGCGTCGGGACGCAGCAAAGAGAGGAGAG ACCCCAGAGTCAGAAGGAGTGAGAACCCTGACCCCTAATCCCACTGCATCCAGCCAATAGGAGCCCAGCCACCATGGCGGAGCTGCAGGAGGTGCAGATC ACAGAGGAGAAGCCACTGTTGCCAGGACAGACGCCTGAGGCGGCCAAGACTCACTCTGTGGAGACACCATACGGCTCTGTCACTTTCACTGTCTATGGCA CCCCCAAACCCAAACGCCCAGCGATCCTTACCTACCACGATGTGGGACTCAACTATAAATCTTGCTTCCAGCCACTGTTTCAGTTCGAGGACATGCAGGA AATCATTCAGAACTTTGTGCGGGTTCATGTGGATGCCCCTGGAATGGAAGAGGGAGCCCCTGTGTTCCCTTTGGGATATCAGTACCCATCTCTGGACCAG CTTGCAGACATGATCCCTTGCGTCCTGCAGTACCTAAATTTCTCTACAATAATTGGAGTTGGTGTTGGAGCTGGAGCCTACATCCTGGCGAGATATGCTC TTAACCACCCGGACACTGTTGAAGGTCTTGTCCTCATCAACATTGATCCCAATGCCAAGGGTTGGATGGATTGGGCAGCCCACAAGCTAACAGGCCTCAC CTCTTCCATTCCGGAGATGATCCTTGGACATCTTTTCAGCCAGGAAGAGCTCTCTGGAAATTCTGAGTTGATACAAAAGTACAGAAATATCATTACACAT GCACCCAACCTGGATAACATTGAATTGTACTGGAACAGCTACAACAACCGCCGAGACCTGAACTTTGAGCGTGGAGGTGATATCACCCTCAGGTGTCCTG TGATGCTGGTGGTAGGAGACCAAGCACCTCATGAAGATGCAGTGGTGGAATGTAACTCAAAACTGGACCCCACCCAGACCTCGTTCCTCAAGATGGCTGA CTCCGGAGGTCAGCCCCAGCTGACTCAGCCAGGCAAGCTGACCGAGGCCTTCAAGTACTTCCTGCAAGGCATGGGCTACATGGCCTCATCCTGCATGACT CGCCTGTCCCGGTCTCGTACAGCCTCTCTGACCAGTGCAGCATCCGTTGATGGCAACCGGTCCCGCTCTCGCACCCTGTCCCAGAGCAGCGAGTCTGGAA CTCTTTCTTCGGGGCCCCCGGGGCACACCATGGAGGTCTCCTGTTGAATGGCCCTTGTTGCCCTAGAGTGGGACCCAGCCCTCACCTCCCCCAGAGCTAA CCTGGGAGGTGCTGAAGGGGCATTGGGCCACCGTAAGCAAGGGAAAAAGGGCAGATCATGCGGGGAGATGACCTTGATCTTTGATTGCTACCCTAACCTT GACCTTTAACCCGTGATTCCCCCCAGCTCCTGGAAGAGATGTCCTAATATCTCTTAGGGACCCAGACCCCTAAATTCTCCTCCTCCCCCATTTTGATGTT AAGGTGGAGAGGGCATATGCATCCTCTGTCCTGATCTAGGTGTCTATAGCTGAGGGGTAAGAGGTTGTTGTAGTTGTCCTGGTGCCTCCATCAGACTCTC CCTACTTGTCCCATATTTGCAAGGGGAGGGGATTTGGGGCTGGGGCTCCATTCACCAAAGCTGAGGTGGCTTCTCATTAACCCTTTAGGACTCTGAAGGG TATGGACCTACGTGAATGTGTGTCAGGGGGAGACTTGCTGGTGGGTTAGTGGTCCTCAGGATGTGATAGAAACATCCAGTGTAAAAAGGAAGTTGGAATG GGAGTTGGCGGGCAGTGAACGAGTGTGGGGAAGGATTGGTGCTGGGGCAACAGGAAGGGGCCTGGGGCCGTTTGGCTGCACTAACTTTGGTAGCTCAGTG TGCATCTAGAGTGGGACTGGGGAGGGAGCTAAGCTTGGGCTGGGCTGCTTGGGGCTTGGCATAGGGTGGAAAGGGCTACCCTGGGGCTCTGACCACACTG TAGTATGTGTGGAGGGTGCCCTCCCGTCTCCCACAACTTCTGCTATAACAATAAACTGTAGAGGAATCTGAGTACCGTTA

refseq_NDRG2.F5 (forward primer)
refseq_NDRG2.R3 (reverse primer)
Single exon skipping

Frame 0

RPPAFPAPTSPPCCPTSPGAAGEQASGRSKERR DPRVRRSENPDP*SHCIQPIGAQPPWRSCRRCRS QRRSHCCQDRRLRRPRLTLWRHHTALSLSLSMA PPNPNAQRSLPTTMWDSTINLASSHCFSSRTCR KSFRTLCGFMWMPLEWKREPLCSLWDISTHLWTS LQT*SLASCST*ISLQ*LELVLELEPTSWRDML LTTRTLLKVLSSSTLIPMPRVGWIGQPTS*QAS PLPFRR*SLDIFSARKSSLEILS*YKSTEISLHM HPTWITLNCTGTATTTAET*TLSVEVISPSGVL *CWW*ETKHLMKMQWWNVTQNWTPPRPRSSRWL TPEVSPS*LSQAS*PRPSSTSCKAWATWPHPA*L ACPGLVQPL*PVQHPLMATGPALAPCPRAASLE LFLRGPRGTPWRSPVEWPLLP*SGTQPSPPPEL TWEVLKGHWATVSKGKRADHAGR*P*SLIATLTL TFNP*FPPAPGRDVLISLRDPDP*ILLLPHFDV KVERAYASSVLI*VSIAEG*EVVVVVLVPPSDS PYLSHICKGRGFGAGAPFTKAEVASH*PFRTLKG MDLRECVSGGDLLVG*WSSGCDRNIQCKKEVGM GVGGQ*TSVGKDWCWGNRKGPGAVWLH*LW*LS VHLEWDWGGS*AWAGLLGAWHRVERATLGL*PHC SMCGGCPPVSHNFCYNNKL*RNLSTV

Frame 1

GPPHSPPPPPRLVVQLLPEQPESRRRDAAKRGE TPESEGVRTLTPNPTASSQ*EPSHHGGAAGGAD HRGEATVARTDA*GGQDSLCGDTIRLCHFHCLWH PQTQTPSDPYLPRCGTQL*ILLPATVSVRGHAG NHSELCAGSCGCPWNGRGSPCVPFGISVPISGP ACRHDPLRPAVPKFLYNNWSWCWSWSLHPGEICS *PPGHC*RSCPHQH*SQCQGLDGLGSPQANRPH LFHSGDDPWTSFQPGRALWKF*VDTKVQKYHYT CTQPG*H*IVLEQLQQPPRPEL*AWR*YHPQVSC DAGGRRPSTS*RCSGGM*LKTGPHPDLVPQDG* LRRSAPADSARQADRGLQVLPARHGLHGLILHD SPVPVSYSLSDQCSIR*WQPVPLSHPVPEQRVWN SFFGAPGAHHGGLLLNGPCCPRVGPSPHLPQS* PGRC*RGIGPP*AREKGQIMRGDDLDL*LLP*P *PLTRDSPQLLEEMS*YLLGTQTPKFSSSPILML RWRGHMHPLS*SRCL*LRGKRLL*LSWCLHQTL PTCPIFARGGDLGLGLHSPKLRWLLINPLGL*R VWTYVNVCQGETCWWVSGPQDVIETSSVKRKLEW ELAGSERVWGRIGAGATGRGLGPFGCTNFGSSV CI*SGTGEGAKLGLGCLGLGIGWKGLPWGSDHT VVCVEGALPSPTTSAITINCRGI*VPL

Frame 2

APRIPRPHLPALLSNFSRSSRRAGVGTQQREER PQSQKE*EP*PLIPLHPANRSPATMAELQEVQI TEEKPLLPGQTPEAAKTHSVETPYGSVTFTVYG TPKPKRPAILTYHDVGLNYKSCFQPLFQFEDMQE IIQNFVRVHVDAPGMEEGAPVFPLGYQYPSLDQ LADMIPCVLQYLNFSTIIGVGVGAGAYILARYA LNHPDTVEGLVLINIDPNAKGWMDWAAHKLTGLT SSIPEMILGHLFSQEELSGNSELIQKYRNIITH APNLDNIELYWNSYNNRRDLNFERGGDITLRCP VMLVVGDQAPHEDAVVECNSKLDPTQTSFLKMAD SGGQPQLTQPGKLTEAFKYFLQGMGYMASSCMT RLSRSRTASLTSAASVDGNRSRSRTLSQSSESG TLSSGPPGHTMEVSC*MALVALEWDPALTSPRAN LGGAEGALGHRKQGKKGRSCGEMTLIFDCYPNL DL*PVIPPSSWKRCPNIS*GPRPLNSPPPPF*C *GGEGICILCPDLGVYS*GVRGCCSCPGASIRLS LLVPYLQGEGIWGWGSIHQS*GGFSLTL*DSEG YGPT*MCVRGRLAGGLVVLRM**KHPV*KGSWN GSWRAVNECGEGLVLGQQEGAWGRLAALTLVAQC ASRVGLGRELSLGWAAWGLA*GGKGYPGALTTL *YVWRVPSRLPQLLL*Q*TVEESEYR

Sequence NM_201535

CGGCCCCCCGCATTCCCCGCCCCCACCTCCCCGCCTTGTTGTCCAACTTCTCCCGGAGCAGCCGGAGAGCAGGCGTCGGGACGCAGCAAAGAGAGGAGAG ACCCCAGAGTCAGAAGGAGTGAGAACCCTGACCCCTAATCCCACTGCATCCAGCCAATAGGAGCCCAGCCACCATGGCGGAGCTGCAGGAGGTGCAGATC ACAGAGGAGAAGCCACTGTTGCCAGGACAGACGCCTGAGGCGGCCAAGGAGGCTGAGTTAGCTGCCCGAATCCTCCTGGACCAGGGACAGACTCACTCTG TGGAGACACCATACGGCTCTGTCACTTTCACTGTCTATGGCACCCCCAAACCCAAACGCCCAGCGATCCTTACCTACCACGATGTGGGACTCAACTATAA ATCTTGCTTCCAGCCACTGTTTCAGTTCGAGGACATGCAGGAAATCATTCAGAACTTTGTGCGGGTTCATGTGGATGCCCCTGGAATGGAAGAGGGAGCC CCTGTGTTCCCTTTGGGATATCAGTACCCATCTCTGGACCAGCTTGCAGACATGATCCCTTGCGTCCTGCAGTACCTAAATTTCTCTACAATAATTGGAG TTGGTGTTGGAGCTGGAGCCTACATCCTGGCGAGATATGCTCTTAACCACCCGGACACTGTTGAAGGTCTTGTCCTCATCAACATTGATCCCAATGCCAA GGGTTGGATGGATTGGGCAGCCCACAAGCTAACAGGCCTCACCTCTTCCATTCCGGAGATGATCCTTGGACATCTTTTCAGCCAGGAAGAGCTCTCTGGA AATTCTGAGTTGATACAAAAGTACAGAAATATCATTACACATGCACCCAACCTGGATAACATTGAATTGTACTGGAACAGCTACAACAACCGCCGAGACC TGAACTTTGAGCGTGGAGGTGATATCACCCTCAGGTGTCCTGTGATGCTGGTGGTAGGAGACCAAGCACCTCATGAAGATGCAGTGGTGGAATGTAACTC AAAACTGGACCCCACCCAGACCTCGTTCCTCAAGATGGCTGACTCCGGAGGTCAGCCCCAGCTGACTCAGCCAGGCAAGCTGACCGAGGCCTTCAAGTAC TTCCTGCAAGGCATGGGCTACATGGCCTCATCCTGCATGACTCGCCTGTCCCGGTCTCGTACAGCCTCTCTGACCAGTGCAGCATCCGTTGATGGCAACC GGTCCCGCTCTCGCACCCTGTCCCAGAGCAGCGAGTCTGGAACTCTTTCTTCGGGGCCCCCGGGGCACACCATGGAGGTCTCCTGTTGAATGGCCCTTGT TGCCCTAGAGTGGGACCCAGCCCTCACCTCCCCCAGAGCTAACCTGGGAGGTGCTGAAGGGGCATTGGGCCACCGTAAGCAAGGGAAAAAGGGCAGATCA TGCGGGGAGATGACCTTGATCTTTGATTGCTACCCTAACCTTGACCTTTAACCCGTGATTCCCCCCAGCTCCTGGAAGAGATGTCCTAATATCTCTTAGG GACCCAGACCCCTAAATTCTCCTCCTCCCCCATTTTGATGTTAAGGTGGAGAGGGCATATGCATCCTCTGTCCTGATCTAGGTGTCTATAGCTGAGGGGT AAGAGGTTGTTGTAGTTGTCCTGGTGCCTCCATCAGACTCTCCCTACTTGTCCCATATTTGCAAGGGGAGGGGATTTGGGGCTGGGGCTCCATTCACCAA AGCTGAGGTGGCTTCTCATTAACCCTTTAGGACTCTGAAGGGTATGGACCTACGTGAATGTGTGTCAGGGGGAGACTTGCTGGTGGGTTAGTGGTCCTCA GGATGTGATAGAAACATCCAGTGTAAAAAGGAAGTTGGAATGGGAGTTGGCGGGCAGTGAACGAGTGTGGGGAAGGATTGGTGCTGGGGCAACAGGAAGG GGCCTGGGGCCGTTTGGCTGCACTAACTTTGGTAGCTCAGTGTGCATCTAGAGTGGGACTGGGGAGGGAGCTAAGCTTGGGCTGGGCTGCTTGGGGCTTG GCATAGGGTGGAAAGGGCTACCCTGGGGCTCTGACCACACTGTAGTATGTGTGGAGGGTGCCCTCCCGTCTCCCACAACTTCTGCTATAACAATAAACTG TAGAGGAATCTGAGTACCGTTA

refseq_NDRG2.F5 (forward primer)
refseq_NDRG2.R3 (reverse primer)
Single exon skipping

Frame 0

RPPAFPAPTSPPCCPTSPGAAGEQASGRSKERR DPRVRRSENPDP*SHCIQPIGAQPPWRSCRRCRS QRRSHCCQDRRLRRPRRLS*LPESSWTRDRLTL WRHHTALSLSLSMAPPNPNAQRSLPTTMWDSTI NLASSHCFSSRTCRKSFRTLCGFMWMPLEWKREP LCSLWDISTHLWTSLQT*SLASCST*ISLQ*LE LVLELEPTSWRDMLLTTRTLLKVLSSSTLIPMP RVGWIGQPTS*QASPLPFRR*SLDIFSARKSSLE ILS*YKSTEISLHMHPTWITLNCTGTATTTAET *TLSVEVISPSGVL*CWW*ETKHLMKMQWWNVT QNWTPPRPRSSRWLTPEVSPS*LSQAS*PRPSST SCKAWATWPHPA*LACPGLVQPL*PVQHPLMAT GPALAPCPRAASLELFLRGPRGTPWRSPVEWPL LP*SGTQPSPPPELTWEVLKGHWATVSKGKRADH AGR*P*SLIATLTLTFNP*FPPAPGRDVLISLR DPDP*ILLLPHFDVKVERAYASSVLI*VSIAEG *EVVVVVLVPPSDSPYLSHICKGRGFGAGAPFTK AEVASH*PFRTLKGMDLRECVSGGDLLVG*WSS GCDRNIQCKKEVGMGVGGQ*TSVGKDWCWGNRK GPGAVWLH*LW*LSVHLEWDWGGS*AWAGLLGAW HRVERATLGL*PHCSMCGGCPPVSHNFCYNNKL *RNLSTV

Frame 1

GPPHSPPPPPRLVVQLLPEQPESRRRDAAKRGE TPESEGVRTLTPNPTASSQ*EPSHHGGAAGGAD HRGEATVARTDA*GGQGG*VSCPNPPGPGTDSLC GDTIRLCHFHCLWHPQTQTPSDPYLPRCGTQL* ILLPATVSVRGHAGNHSELCAGSCGCPWNGRGS PCVPFGISVPISGPACRHDPLRPAVPKFLYNNWS WCWSWSLHPGEICS*PPGHC*RSCPHQH*SQCQ GLDGLGSPQANRPHLFHSGDDPWTSFQPGRALW KF*VDTKVQKYHYTCTQPG*H*IVLEQLQQPPRP EL*AWR*YHPQVSCDAGGRRPSTS*RCSGGM*L KTGPHPDLVPQDG*LRRSAPADSARQADRGLQV LPARHGLHGLILHDSPVPVSYSLSDQCSIR*WQP VPLSHPVPEQRVWNSFFGAPGAHHGGLLLNGPC CPRVGPSPHLPQS*PGRC*RGIGPP*AREKGQI MRGDDLDL*LLP*P*PLTRDSPQLLEEMS*YLLG TQTPKFSSSPILMLRWRGHMHPLS*SRCL*LRG KRLL*LSWCLHQTLPTCPIFARGGDLGLGLHSP KLRWLLINPLGL*RVWTYVNVCQGETCWWVSGPQ DVIETSSVKRKLEWELAGSERVWGRIGAGATGR GLGPFGCTNFGSSVCI*SGTGEGAKLGLGCLGL GIGWKGLPWGSDHTVVCVEGALPSPTTSAITINC RGI*VPL

Frame 2

APRIPRPHLPALLSNFSRSSRRAGVGTQQREER PQSQKE*EP*PLIPLHPANRSPATMAELQEVQI TEEKPLLPGQTPEAAKEAELAARILLDQGQTHS VETPYGSVTFTVYGTPKPKRPAILTYHDVGLNYK SCFQPLFQFEDMQEIIQNFVRVHVDAPGMEEGA PVFPLGYQYPSLDQLADMIPCVLQYLNFSTIIG VGVGAGAYILARYALNHPDTVEGLVLINIDPNAK GWMDWAAHKLTGLTSSIPEMILGHLFSQEELSG NSELIQKYRNIITHAPNLDNIELYWNSYNNRRD LNFERGGDITLRCPVMLVVGDQAPHEDAVVECNS KLDPTQTSFLKMADSGGQPQLTQPGKLTEAFKY FLQGMGYMASSCMTRLSRSRTASLTSAASVDGN RSRSRTLSQSSESGTLSSGPPGHTMEVSC*MALV ALEWDPALTSPRANLGGAEGALGHRKQGKKGRS CGEMTLIFDCYPNLDL*PVIPPSSWKRCPNIS* GPRPLNSPPPPF*C*GGEGICILCPDLGVYS*GV RGCCSCPGASIRLSLLVPYLQGEGIWGWGSIHQ S*GGFSLTL*DSEGYGPT*MCVRGRLAGGLVVL RM**KHPV*KGSWNGSWRAVNECGEGLVLGQQEG AWGRLAALTLVAQCASRVGLGRELSLGWAAWGL A*GGKGYPGALTTL*YVWRVPSRLPQLLL*Q*T VEESEYR