Sequences - Rnomics 📊 Palace

        ☰
    
        Rnomics 📊 Palace
    
                       Back to Rnomics Platform
            
                       Open Session

1 warning:

Access restricted to public data.
Please sign in at Rnomics Platform to access your data.

Navigation

Home

Sequences

Sequence NM_001011649

AGGAAGAAGCGCCGGGAAAGATGGCGGCGTCTGTGGTTTGAATTCCAGCGGCGCCGCCAGAGTCTGAACAAGAGCTGGGGTGGAGGGGGCGGGGACCTGG GGAGCCCGGCGGGTCGCTATCGCGGGGGGTACTAGTGGCGCCGCCGCCACAGACACCAACGCTGTCGCCACCTCTGTAGCCATGATGGACTTGGTGTTGG AAGAGGACGTCACCGTCCCTGGGACGCTCAGCGGCTGCAGTGGCCTTGTTCCCAGTGTACCAGATGACCTGGATGGCATCAACCCCAATGCTGGGTTGGG AAATGGTCTGCTCCCAAATGTGTCAGAAGAAACAGTGTCTCCCACCAGAGCACGGAACATGAAGGACTTTGAAAATCAAATCACTGAATTGAAGAAAGAA AACTTTAACCTAAAGCTCCGCATCTATTTCCTTGAGGAAAGAATGCAACAGGAATTTCATGGCCCCACTGAACATATCTACAAAACTAACATTGAGCTCA AGGTGGAAGTAGAAAGTCTGAAGCGGGAACTCCAGGAGAGAGAGCAGCTGCTCATCAAAGCCTCCAAAGCAGTTGAGAGCTTAGCTGAAGCAGGTGGCTC TGAAATCCAGCGGGTGAAAGAAGATGCTCGAAAGAAGGTGCAGCAGGTGGAAGATCTCCTAACTAAAAGAATACTCCTTTTGGAAAAGGATGTGACAGCC GCCCAGGCAGAACTGGAAAAGGCCTTTGCAGGGACAGAGACGGAGAAGGCTCTTCGGTTGCGTTTGGAAAGCAAGCTTTCAGAGATGAAGAAGATGCACG AGGGGGACTTGGCGATGGCTCTGGTCCTGGATGAGAAAGACAGACTGATTGAGGAGTTGAAGCTGTCTTTGAAGAGCAAAGAAGCTTTAATTCAGTGCCT TAAAGAGGAGAAATCTCAGATGGCATGTCCTGATGAGAATGTGTCATCTGGAGAGCTCCGAGGACTTTGTGCTGCTCCAAGGGAAGAAAAGGAGAGAGAA ACTGAGGCTGCACAAATGGAGCATCAGAAGGAGAGAAACAGCTTTGAAGAGAGGATCCAGGCACTTGAAGAGGACCTGAGAGAGAAGGAAAGAGAAATTG CTACAGAGAAGAAAAATAGTCTAAAGAGGGATAAAGCCATTCAGGGTTTAACCATGGCATTAAAATCAAAGGAAAAAAAGGTTGAAGAACTTAACTCTGA AATTGAAAAGCTCAGTGCTGCCTTTGCTAAAGCCAGAGAGGCCCTACAGAAAGCACAGACCCAGGAATTTCAGGGGTCTGAAGACTATGAGACTGCTCTA TCAGGAAAGGAAGCCCTTTCGGCTGCGCTGCGCTCACAAAACCTCACCAAGAGTACAGAGAACCACAGACTGCGTAGAAGCATTAAGAAGATCACCCAGG AGCTGAGTGACTTGCAGCAGGAGAGGGAGAGACTGGAGAAGGACCTGGAGGAAGCCCATCGAGAGAAGAGCAAAGGAGACTGCACCATCCGTGATCTTAG AAATGAAGTTGAAAAATTACGCAATGAAGTGAATGAAAGAGAGAAAGCAATGGAAAATCGTTACAAGAGTCTTCTGAGTGAAAGCAATAAAAAATTGCAC AATCAAGAGCAAGTGATCAAACATCTAACAGAAAGTACCAATCAGAAGGACGTGTTGCTTCAGAAATTCAATGAAAAAGATTTGGAAGTAATACAGCAGA ACTGCTATTTAATGGCTGCAGAGGATCTTGAGCTCAGGAGTGAAGGCTTAATAACAGAAAAGTGCTCTTCTCAACAGCCACCAGGCAGCAAAACCATCTT CTCTAAGGAAAAGAAACAATCATCAGACTATGAAGAGCTGATTCAGGTCTTAAAGAAAGAGCAGGACATCTATACCCATCTGGTCAAATCTCTGCAGGAA TCAGACAGTATCAACAACCTGCAGGCTGAGTTAAACAAGATTTTTGCCCTGCGGAAGCAACTGGAGCAGGATGTGCTTTCATATCAGAATTTGCGGAAGA CCTTGGAGGAGCAGATCAGCGAAATTCGGAGGCGGGAAGAAGAATCATTTTCACTTTATAGTGATCAAACATCTTATCTAAGTATTTGCCTTGAAGAAAA CAATCGGTTTCAAGTGGAACATTTTTCTCAAGAAGAACTTAAGAAAAAGGTCAGTGACCTTATACAGCTAGTGAAGGAGCTGTATACAGACAACCAGCAC CTGAAGAAAACCATTTTTGATCTCTCCTGCATGGGTTTCCAGGGAAATGGGTTTCCAGATAGACTTGCGTCTACAGAACAAACAGAGCTTCTGGCTAGCA AGGAGGACGAGGACACGATCAAAATTGGGGAGGATGACGAGATTAATTTCCTGAGTGACCAGCATTTGCAGCAGAGTAATGAGATTATGAAAGACCTTTC CAAAGGAGGCTGCAAAAATGGATACTTAAGGCACACGGAGTCTAAGATTTCAGATTGTGATGGGGCCCACGCACCTGGCTGCCTAGAAGAAGGTGCATTC ATAAACCTGCTTGCCCCTTTGTTCAATGAGAAGGCCACATTATTACTGGAATCCAGGCCAGACCTTCTGAAAGTGGTACGGGAACTGCTTCTGGGACAAC TATTCTTGACAGAGCAGGAAGTTTCTGGAGAACACCTTGATGGTAAAACTGAGAAGACACCTAAGCAAAAAGGTGAACTTGTACATTTTGTCCAAACCAA CTCATTTTCCAAGCCACATGATGAACTGAAGTTGTCTTGTGAGGCCCAGCTAGTAAAGGCAGGCGAAGTGCCCAAGGTAGGACTGAAAGATGCCTCAGTG CAGACTGTGGCCACGGAGGGCGACCTGCTGAGATTCAAGCATGAAGCAACAAGAGAGGCTTGGGAAGAGAAACCGATCAACACTGCACTCAGCGCAGAGC ATCGGCCAGAGAACCTGCACGGGGTGCCTGGGTGGCAGGCTGCCCTCCTTTCCCTCCCTGGTATTACCAACAGAGAGGCTAAGAAGTCCCGCTTGCCAAT CCTAATAAAACCATCCCGGTCATTAGGAAATATGTATCGTCTCCCTGCCACCCAGGAGGTGGTGACGCAGCTGCAGAGCCAGATCTTGGAGCTGCAGGGG GAGCTGAAGGAGTTTAAAACTTGTAATAAGCAACTTCACCAAAAGTTAATTCTGGCTGAAGCAGTGATGGAGGGGAGGCCAACGCCCGACAAAACGTTGC TGAATGCTCAGCCCCCTGTGGGAGCAGCCTACCAGGACAGCCCAGGAGAGCAGAAAGGAATTAAAACCACATCTTCTGTCTGGAGAGACAAGGAAATGGA CAGTGATCAGCAAAGAAGCTACGAGATTGACTCTGAGATTTGCCCACCTGATGACCTTGCCAGCTTGCCATCATGCAAAGAAAATCCTGAAGATGTTCTG AGCCCAACTTCAGTAGCTACTTACCTGAGTTCCAAGAGTCAGCCTTCTGCTAAAGTCAGTGTGATGGGGACTGATCAGTCAGAGAGCATTAATACCTCAA ATGAGACAGAATACTTAAAACAGAAAATCCATGACTTGGAAACTGAGCTGGAAGGCTACCAGAATTTCATATTTCAGCTTCAAAAGCACTCCCAGTGCAG TGAGGCCATAATTACAGTTTTGTGTGGGACAGAAGGGGCCCAGGATGGCTTGAGCAAGCCCAAGAATGGTTCTGATGGGGAAGAAATGACCTTTTCAAGT TTGCACCAAGTGCGATACGTGAAACACGTGAAAATCCTCGGTCCGCTGGCCCCAGAGATGATTGACAGCAGGGTGCTGGAGAACCTCAAACAGCAGCTGG AGGAACAGGAATACAAGCTGCAGAAGGAGCAGAATTTGAACATGCAACTTTTCAGTGAGATCCATAATCTGCAGAATAAGTTCAGAGATCTCTCACCTCC CAGATACGATTCATTAGTTCAGTCCCAAGCCAGGGAGCTCTCCCTTCAACGGCAGCAGATTAAGGATGGCCATGGCATCTGTGTCATCTCCCGTCAACAC ATGAACACCATGATTAAGGCATTTGAGGAGTTGCTGCAGGCCAGTGATGTGGATTACTGTGTGGCCGAGGGTTTCCAGGAACAGCTGAATCAATGTGCTG AGCTGCTGGAGAAATTGGAAAAGCTATTTCTCAACGGAAAATCAGTTGGAGTGGAAATGAACACCCAGAATGAACTGATGGAGAGGATTGAGGAAGACAA CTTAACCTACCAACATCTTCTGCCTGAATCTCCTGAGCCTTCAGCCTCTCATGCGCTCTCTGATTATGAAACATCTGAAAAGTCCTTCTTCTCACGAGAC CAGAAGCAAGATAATGAGACAGAGAAGACTTCAGTTATGGTGAACAGTTTTTCTCAAGACTTACTAATGGAACACATACAGGAAATTCGAACTTTGAGAA AGCGTTTAGAAGAATCTATTAAAACAAATGAGAAGCTACGGAAACAGTTGGAACGGCAAGGATCTGAATTTGTTCAAGGTTCTACAAGCATTTTTGCTTC TGGTTCAGAGCTTCATAGTTCTCTAACATCAGAAATTCATTTCTTGAGGAAGCAGAACCAGGCCCTCAATGCAATGCTCATTAAAGGATCCAGAGATAAA CAGAAGGAGAATGACAAATTACGAGAGTCCCTCTCCAGGAAGACCGTGAGCCTGGAGCACCTTCAGCGGGAGTATGCCAGCGTGAAGGAAGAAAATGAAA GGCTGCAGAAAGAAGGCAGCGAGAAGGAGAGACACAACCAGCAGCTGATCCAGGAGGTCCGCTGCAGCGGCCAGGAGCTGAGCAGGGTGCAGGAGGAGGT GAAGTTGAGGCAGCAGCTGCTCTCACAGAATGACAAGCTATTGCAGTCTCTCCGAGTGGAGCTGAAGGCGTATGAGAAGCTGGATGAAGAGCACAGGAGA CTGAGAGATGGTGACAAATATCCCATGGAAAGTGATAATTCATTTGATCTGTTTGATTCCTCCCAGGCAGTGACACCAAAATCAGTTTCAGAGACTCCTC CACTCTCTGGGAATGACACGGACTCCCTCTCCTGCGACAGTGGCAGTTCGGCAACTAGCACTCCGTGTGTGTCCCGCCTGGTCACTGGCCACCACCTGTG GGCCAGCAAGAATGGCCGCCATGTCCTGGGCCTGATTGAGGACTATGAGGCCCTGCTCAAACAGATCAGCCAGGGACAGAGGCTCCTTGCTGAAATGGAC ATTCAAACCCAAGAGGCTCCCAGCTCCACAAGTCAAGAGCTGGGAACAAAGGGTCCACACCCAGCACCACTGAGCAAGTTTGTGAGCAGTGTGAGCACGG CCAAGCTGACCCTGGAAGAGGCCTACAGGCGGCTGAAGCTTCTCTGGAGAGTCTCACTCCCCGAGGATGGCCAGTGCCCCCTTCACTGTGAGCAGATTGG AGAAATGAAGGCAGAGGTCACCAAACTACATAAAAAATTGTTTGAACAAGAAAAGAAGTTGCAAAACACCATGAAGCTTTTGCAGCTGAGCAAGCGCCAG GAAAAAGTCATCTTTGATCAATTGGTCGTAACCCACAAAATCCTTCGGAAGGCCAGAGGAAACCTGGAGCTTAGGCCTGGGGGAGCCCATCCAGGAACAT GCAGTCCCAGCAGACCAGGCTCCTGAGAAGAACTTTCAGCCAATAAAGCTTGTGCTTCCCCCACCGAGCTCACGCTGTCTCTTTGTTCCAAGTGTGGTTC CTATTTATTGAGGAAGAAAGAGCTGTCTGGCCAAAGGAAATCTATTTTTTCCCTTCATGTTTTCTCTCTGAAAGTTGGCTTGAGAGTTGTTGTCAGAAAG GTGCAGGTGCTCCACAAACGGGTGGTAAAAAGGCCTCGAGCTCTTGGATGTTGTATTTCAGATCAGGGGCAGGCACCGGAGTTGAGGCTGTGCGCCTTGG TGGGCTTCACGTCTTCCCCTGGATTTGCTTAGTACTCAGCCAGTGCCACAGTTTGAAGATTCTCATTAAATGATTCATTTCATTTCACCTTGA

refseq_CDK5RAP2.F1 (forward primer)
refseq_CDK5RAP2.R1 (reverse primer)
Single exon skipping

Frame 0

RKKRRERWRRLWFEFQRRRQSLNKSWGGGGGDL GSPAGRYRGGY*WRRRHRHQRCRHLCSHDGLGVG RGRHRPWDAQRLQWPCSQCTR*PGWHQPQCWVG KWSAPKCVRRNSVSHQSTEHEGL*KSNH*IEER KL*PKAPHLFP*GKNATGISWPH*TYLQN*H*AQ GGSRKSEAGTPGERAAAHQSLQSS*ELS*SRWL *NPAGERRCSKEGAAGGRSPN*KNTPFGKGCDS RPGRTGKGLCRDRDGEGSSVAFGKQAFRDEEDAR GGLGDGSGPG*ERQTD*GVEAVFEEQRSFNSVP *RGEISDGMS**ECVIWRAPRTLCCSKGRKGER N*GCTNGASEGEKQL*REDPGT*RGPEREGKRNC YREEK*SKEG*SHSGFNHGIKIKGKKG*RT*L* N*KAQCCLC*SQRGPTESTDPGISGV*RL*DCS IRKGSPFGCAALTKPHQEYREPQTA*KH*EDHPG AE*LAAGEGETGEGPGGSPSREEQRRLHHP*S* K*S*KITQ*SE*KRESNGKSLQESSE*KQ*KIA QSRASDQTSNRKYQSEGRVASEIQ*KRFGSNTAE LLFNGCRGS*AQE*RLNNRKVLFSTATRQQNHL L*GKETIIRL*RADSGLKERAGHLYPSGQISAG IRQYQQPAG*VKQDFCPAEATGAGCAFISEFAED LGGADQRNSEAGRRIIFTL**SNILSKYLP*RK QSVSSGTFFSRRT*EKGQ*PYTASEGAVYRQPA PEENHF*SLLHGFPGKWVSR*TCVYRTNRASG*Q GGRGHDQNWGG*RD*FPE*PAFAAE**DYERPF QRRLQKWILKAHGV*DFRL*WGPRTWLPRRRCI HKPACPFVQ*EGHIITGIQARPSESGTGTASGTT ILDRAGSFWRTP*W*N*EDT*AKR*TCTFCPNQ LIFQAT**TEVVL*GPASKGRRSAQGRTERCLS ADCGHGGRPAEIQA*SNKRGLGRETDQHCTQRRA SAREPARGAWVAGCPPFPPWYYQQRG*EVPLAN PNKTIPVIRKYVSSPCHPGGGDAAAEPDLGAAG GAEGV*NL**ATSPKVNSG*SSDGGEANARQNVA ECSAPCGSSLPGQPRRAERN*NHIFCLERQGNG Q*SAKKLRD*L*DLPT**PCQLAIMQRKS*RCS EPNFSSYLPEFQESAFC*SQCDGD*SVREH*YLK *DRILKTENP*LGN*AGRLPEFHISASKALPVQ *GHNYSFVWDRRGPGWLEQAQEWF*WGRNDLFK FAPSAIRETRENPRSAGPRDD*QQGAGEPQTAAG GTGIQAAEGAEFEHATFQ*DP*SAE*VQRSLTS QIRFISSVPSQGALPSTAAD*GWPWHLCHLPST HEHHD*GI*GVAAGQ*CGLLCGRGFPGTAESMC* AAGEIGKAISQRKISWSGNEHPE*TDGED*GRQ LNLPTSSA*IS*AFSLSCAL*L*NI*KVLLLTR PEAR**DREDFSYGEQFFSRLTNGTHTGNSNFEK AFRRIY*NK*EATETVGTARI*ICSRFYKHFCF WFRAS*FSNIRNSFLEEAEPGPQCNAH*RIQR* TEGE*QITRVPLQEDREPGAPSAGVCQREGRK*K AAERRQREGETQPAADPGGPLQRPGAEQGAGGG EVEAAAALTE*QAIAVSPSGAEGV*EAG*RAQE TERW*QISHGK**FI*SV*FLPGSDTKISFRDSS TLWE*HGLPLLRQWQFGN*HSVCVPPGHWPPPV GQQEWPPCPGPD*GL*GPAQTDQPGTEAPC*NG HSNPRGSQLHKSRAGNKGSTPSTTEQVCEQCEHG QADPGRGLQAAEASLESLTPRGWPVPPSL*ADW RNEGRGHQTT*KIV*TRKEVAKHHEAFAAEQAP GKSHL*SIGRNPQNPSEGQRKPGA*AWGSPSRNM QSQQTRLLRRTFSQ*SLCFPHRAHAVSLFQVWF LFIEEERAVWPKEIYFFPSCFLSESWLESCCQK GAGAPQTGGKKASSSWMLYFRSGAGTGVEAVRLG GLHVFPWICLVLSQCHSLKILIK*FISFHL

Frame 1

GRSAGKDGGVCGLNSSGAARV*TRAGVEGAGTW GARRVAIAGGTSGAAATDTNAVATSVAMMDLVL EEDVTVPGTLSGCSGLVPSVPDDLDGINPNAGLG NGLLPNVSEETVSPTRARNMKDFENQITELKKE NFNLKLRIYFLEERMQQEFHGPTEHIYKTNIEL KVEVESLKRELQEREQLLIKASKAVESLAEAGGS EIQRVKEDARKKVQQVEDLLTKRILLLEKDVTA AQAELEKAFAGTETEKALRLRLESKLSEMKKMH EGDLAMALVLDEKDRLIEELKLSLKSKEALIQCL KEEKSQMACPDENVSSGELRGLCAAPREEKERE TEAAQMEHQKERNSFEERIQALEEDLREKEREI ATEKKNSLKRDKAIQGLTMALKSKEKKVEELNSE IEKLSAAFAKAREALQKAQTQEFQGSEDYETAL SGKEALSAALRSQNLTKSTENHRLRRSIKKITQ ELSDLQQERERLEKDLEEAHREKSKGDCTIRDLR NEVEKLRNEVNEREKAMENRYKSLLSESNKKLH NQEQVIKHLTESTNQKDVLLQKFNEKDLEVIQQ NCYLMAAEDLELRSEGLITEKCSSQQPPGSKTIF SKEKKQSSDYEELIQVLKKEQDIYTHLVKSLQE SDSINNLQAELNKIFALRKQLEQDVLSYQNLRK TLEEQISEIRRREEESFSLYSDQTSYLSICLEEN NRFQVEHFSQEELKKKVSDLIQLVKELYTDNQH LKKTIFDLSCMGFQGNGFPDRLASTEQTELLAS KEDEDTIKIGEDDEINFLSDQHLQQSNEIMKDLS KGGCKNGYLRHTESKISDCDGAHAPGCLEEGAF INLLAPLFNEKATLLLESRPDLLKVVRELLLGQ LFLTEQEVSGEHLDGKTEKTPKQKGELVHFVQTN SFSKPHDELKLSCEAQLVKAGEVPKVGLKDASV QTVATEGDLLRFKHEATREAWEEKPINTALSAE HRPENLHGVPGWQAALLSLPGITNREAKKSRLPI LIKPSRSLGNMYRLPATQEVVTQLQSQILELQG ELKEFKTCNKQLHQKLILAEAVMEGRPTPDKTL LNAQPPVGAAYQDSPGEQKGIKTTSSVWRDKEMD SDQQRSYEIDSEICPPDDLASLPSCKENPEDVL SPTSVATYLSSKSQPSAKVSVMGTDQSESINTS NETEYLKQKIHDLETELEGYQNFIFQLQKHSQCS EAIITVLCGTEGAQDGLSKPKNGSDGEEMTFSS LHQVRYVKHVKILGPLAPEMIDSRVLENLKQQL EEQEYKLQKEQNLNMQLFSEIHNLQNKFRDLSPP RYDSLVQSQARELSLQRQQIKDGHGICVISRQH MNTMIKAFEELLQASDVDYCVAEGFQEQLNQCA ELLEKLEKLFLNGKSVGVEMNTQNELMERIEEDN LTYQHLLPESPEPSASHALSDYETSEKSFFSRD QKQDNETEKTSVMVNSFSQDLLMEHIQEIRTLR KRLEESIKTNEKLRKQLERQGSEFVQGSTSIFAS GSELHSSLTSEIHFLRKQNQALNAMLIKGSRDK QKENDKLRESLSRKTVSLEHLQREYASVKEENE RLQKEGSEKERHNQQLIQEVRCSGQELSRVQEEV KLRQQLLSQNDKLLQSLRVELKAYEKLDEEHRR LRDGDKYPMESDNSFDLFDSSQAVTPKSVSETP PLSGNDTDSLSCDSGSSATSTPCVSRLVTGHHLW ASKNGRHVLGLIEDYEALLKQISQGQRLLAEMD IQTQEAPSSTSQELGTKGPHPAPLSKFVSSVST AKLTLEEAYRRLKLLWRVSLPEDGQCPLHCEQIG EMKAEVTKLHKKLFEQEKKLQNTMKLLQLSKRQ EKVIFDQLVVTHKILRKARGNLELRPGGAHPGT CSPSRPGS*EELSANKACASPTELTLSLCSKCGS YLLRKKELSGQRKSIFSLHVFSLKVGLRVVVRK VQVLHKRVVKRPRALGCCISDQGQAPELRLCAL VGFTSSPGFA*YSASATV*RFSLNDSFHFTL

Frame 2

EEAPGKMAASVV*IPAAPPESEQELGWRGRGPG EPGGSLSRGVLVAPPPQTPTLSPPL*P*WTWCW KRTSPSLGRSAAAVALFPVYQMTWMASTPMLGW EMVCSQMCQKKQCLPPEHGT*RTLKIKSLN*RKK TLT*SSASISLRKECNRNFMAPLNISTKLTLSS RWK*KV*SGNSRRESSCSSKPPKQLRA*LKQVA LKSSG*KKMLERRCSRWKIS*LKEYSFWKRM*QP PRQNWKRPLQGQRRRRLFGCVWKASFQR*RRCT RGTWRWLWSWMRKTD*LRS*SCL*RAKKL*FSA LKRRNLRWHVLMRMCHLESSEDFVLLQGKKRREK LRLHKWSIRRRETALKRGSRHLKRT*ERRKEKL LQRRKIV*RGIKPFRV*PWH*NQRKKRLKNLTL KLKSSVLPLLKPERPYRKHRPRNFRGLKTMRLLY QERKPFRLRCAHKTSPRVQRTTDCVEALRRSPR S*VTCSRRGRDWRRTWRKPIERRAKETAPSVIL EMKLKNYAMK*MKERKQWKIVTRVF*VKAIKNCT IKSK*SNI*QKVPIRRTCCFRNSMKKIWK*YSR TAI*WLQRILSSGVKA**QKSALLNSHQAAKPS SLRKRNNHQTMKS*FRS*RKSRTSIPIWSNLCRN QTVSTTCRLS*TRFLPCGSNWSRMCFHIRICGR PWRSRSAKFGGGKKNHFHFIVIKHLI*VFALKK TIGFKWNIFLKKNLRKRSVTLYS**RSCIQTTST *RKPFLISPAWVSREMGFQIDLRLQNKQSFWLA RRTRTRSKLGRMTRLIS*VTSICSRVMRL*KTF PKEAAKMDT*GTRSLRFQIVMGPTHLAA*KKVHS *TCLPLCSMRRPHYYWNPGQTF*KWYGNCFWDN YS*QSRKFLENTLMVKLRRHLSKKVNLYILSKP THFPSHMMN*SCLVRPS**RQAKCPR*D*KMPQC RLWPRRATC*DSSMKQQERLGKRNRSTLHSAQS IGQRTCTGCLGGRLPSFPSLVLPTERLRSPACQ S**NHPGH*EICIVSLPPRRW*RSCRARSWSCRG S*RSLKLVISNFTKS*FWLKQ*WRGGQRPTKRC *MLSPLWEQPTRTAQESRKELKPHLLSGETRKW TVISKEATRLTLRFAHLMTLPACHHAKKILKMF* AQLQ*LLT*VPRVSLLLKSV*WGLISQRALIPQ MRQNT*NRKSMTWKLSWKATRISYFSFKSTPSA VRP*LQFCVGQKGPRMA*ASPRMVLMGKK*PFQV CTKCDT*NT*KSSVRWPQR*LTAGCWRTSNSSW RNRNTSCRRSRI*TCNFSVRSIICRISSEISHL PDTIH*FSPKPGSSPFNGSRLRMAMASVSSPVNT *TP*LRHLRSCCRPVMWITVWPRVSRNS*INVL SCWRNWKSYFSTENQLEWK*TPRMN*WRGLRKT T*PTNIFCLNLLSLQPLMRSLIMKHLKSPSSHET RSKIMRQRRLQLW*TVFLKTY*WNTYRKFEL*E SV*KNLLKQMRSYGNSWNGKDLNLFKVLQAFLL LVQSFIVL*HQKFIS*GSRTRPSMQCSLKDPEIN RRRMTNYESPSPGRP*AWSTFSGSMPA*RKKMK GCRKKAARRRDTTSS*SRRSAAAARS*AGCRRR *S*GSSCSHRMTSYCSLSEWS*RRMRSWMKSTGD *EMVTNIPWKVIIHLICLIPPRQ*HQNQFQRLL HSLGMTRTPSPATVAVRQLALRVCPAWSLATTC GPARMAAMSWA*LRTMRPCSNRSARDRGSLLKWT FKPKRLPAPQVKSWEQRVHTQHH*ASL*AV*AR PS*PWKRPTGG*SFSGESHSPRMASAPFTVSRL EK*RQRSPNYIKNCLNKKRSCKTP*SFCS*ASAR KKSSLINWS*PTKSFGRPEETWSLGLGEPIQEH AVPADQAPEKNFQPIKLVLPPPSSRCLFVPSVV PIY*GRKSCLAKGNLFFPFMFSL*KLA*ELLSER CRCSTNGW*KGLELLDVVFQIRGRHRS*GCAPW WASRLPLDLLSTQPVPQFEDSH*MIHFISP*

Sequence NM_018249

AGGAAGAAGCGCCGGGAAAGATGGCGGCGTCTGTGGTTTGAATTCCAGCGGCGCCGCCAGAGTCTGAACAAGAGCTGGGGTGGAGGGGGCGGGGACCTGG GGAGCCCGGCGGGTCGCTATCGCGGGGGGTACTAGTGGCGCCGCCGCCACAGACACCAACGCTGTCGCCACCTCTGTAGCCATGATGGACTTGGTGTTGG AAGAGGACGTCACCGTCCCTGGGACGCTCAGCGGCTGCAGTGGCCTTGTTCCCAGTGTACCAGATGACCTGGATGGCATCAACCCCAATGCTGGGTTGGG AAATGGTCTGCTCCCAAATGTGTCAGAAGAAACAGTGTCTCCCACCAGAGCACGGAACATGAAGGACTTTGAAAATCAAATCACTGAATTGAAGAAAGAA AACTTTAACCTAAAGCTCCGCATCTATTTCCTTGAGGAAAGAATGCAACAGGAATTTCATGGCCCCACTGAACATATCTACAAAACTAACATTGAGCTCA AGGTGGAAGTAGAAAGTCTGAAGCGGGAACTCCAGGAGAGAGAGCAGCTGCTCATCAAAGCCTCCAAAGCAGTTGAGAGCTTAGCTGAAGCAGGTGGCTC TGAAATCCAGCGGGTGAAAGAAGATGCTCGAAAGAAGGTGCAGCAGGTGGAAGATCTCCTAACTAAAAGAATACTCCTTTTGGAAAAGGATGTGACAGCC GCCCAGGCAGAACTGGAAAAGGCCTTTGCAGGGACAGAGACGGAGAAGGCTCTTCGGTTGCGTTTGGAAAGCAAGCTTTCAGAGATGAAGAAGATGCACG AGGGGGACTTGGCGATGGCTCTGGTCCTGGATGAGAAAGACAGACTGATTGAGGAGTTGAAGCTGTCTTTGAAGAGCAAAGAAGCTTTAATTCAGTGCCT TAAAGAGGAGAAATCTCAGATGGCATGTCCTGATGAGAATGTGTCATCTGGAGAGCTCCGAGGACTTTGTGCTGCTCCAAGGGAAGAAAAGGAGAGAGAA ACTGAGGCTGCACAAATGGAGCATCAGAAGGAGAGAAACAGCTTTGAAGAGAGGATCCAGGCACTTGAAGAGGACCTGAGAGAGAAGGAAAGAGAAATTG CTACAGAGAAGAAAAATAGTCTAAAGAGGGATAAAGCCATTCAGGGTTTAACCATGGCATTAAAATCAAAGGAAAAAAAGGTTGAAGAACTTAACTCTGA AATTGAAAAGCTCAGTGCTGCCTTTGCTAAAGCCAGAGAGGCCCTACAGAAAGCACAGACCCAGGAATTTCAGGGGTCTGAAGACTATGAGACTGCTCTA TCAGGAAAGGAAGCCCTTTCGGCTGCGCTGCGCTCACAAAACCTCACCAAGAGTACAGAGAACCACAGACTGCGTAGAAGCATTAAGAAGATCACCCAGG AGCTGAGTGACTTGCAGCAGGAGAGGGAGAGACTGGAGAAGGACCTGGAGGAAGCCCATCGAGAGAAGAGCAAAGGAGACTGCACCATCCGTGATCTTAG AAATGAAGTTGAAAAATTACGCAATGAAGTGAATGAAAGAGAGAAAGCAATGGAAAATCGTTACAAGAGTCTTCTGAGTGAAAGCAATAAAAAATTGCAC AATCAAGAGCAAGTGATCAAACATCTAACAGAAAGTACCAATCAGAAGGACGTGTTGCTTCAGAAATTCAATGAAAAAGATTTGGAAGTAATACAGCAGA ACTGCTATTTAATGGCTGCAGAGGATCTTGAGCTCAGGAGTGAAGGCTTAATAACAGAAAAGTGCTCTTCTCAACAGCCACCAGGCAGCAAAACCATCTT CTCTAAGGAAAAGAAACAATCATCAGACTATGAAGAGCTGATTCAGGTCTTAAAGAAAGAGCAGGACATCTATACCCATCTGGTCAAATCTCTGCAGGAA TCAGACAGTATCAACAACCTGCAGGCTGAGTTAAACAAGATTTTTGCCCTGCGGAAGCAACTGGAGCAGGATGTGCTTTCATATCAGAATTTGCGGAAGA CCTTGGAGGAGCAGATCAGCGAAATTCGGAGGCGGGAAGAAGAATCATTTTCACTTTATAGTGATCAAACATCTTATCTAAGTATTTGCCTTGAAGAAAA CAATCGGTTTCAAGTGGAACATTTTTCTCAAGAAGAACTTAAGAAAAAGGTCAGTGACCTTATACAGCTAGTGAAGGAGCTGTATACAGACAACCAGCAC CTGAAGAAAACCATTTTTGATCTCTCCTGCATGGGTTTCCAGGGAAATGGGTTTCCAGATAGACTTGCGTCTACAGAACAAACAGAGCTTCTGGCTAGCA AGGAGGACGAGGACACGATCAAAATTGGGGAGGATGACGAGATTAATTTCCTGAGTGACCAGCATTTGCAGCAGAGTAATGAGATTATGAAAGACCTTTC CAAAGGAGGCTGCAAAAATGGATACTTAAGGCACACGGAGTCTAAGATTTCAGATTGTGATGGGGCCCACGCACCTGGCTGCCTAGAAGAAGGTGCATTC ATAAACCTGCTTGCCCCTTTGTTCAATGAGAAGGCCACATTATTACTGGAATCCAGGCCAGACCTTCTGAAAGTGGTACGGGAACTGCTTCTGGGACAAC TATTCTTGACAGAGCAGGAAGTTTCTGGAGAACACCTTGATGGTAAAACTGAGAAGACACCTAAGCAAAAAGGTGAACTTGTACATTTTGTCCAAACCAA CTCATTTTCCAAGCCACATGATGAACTGAAGTTGTCTTGTGAGGCCCAGCTAGTAAAGGCAGGCGAAGTGCCCAAGGTAGGACTGAAAGATGCCTCAGTG CAGACTGTGGCCACGGAGGGCGACCTGCTGAGATTCAAGCATGAAGCAACAAGAGAGGCTTGGGAAGAGAAACCGATCAACACTGCACTCAGCGCAGAGC ATCGGCCAGAGAACCTGCACGGGGTGCCTGGGTGGCAGGCTGCCCTCCTTTCCCTCCCTGGTATTACCAACAGAGAGGCTAAGAAGTCCCGCTTGCCAAT CCTAATAAAACCATCCCGGTCATTAGGAAATATGTATCGTCTCCCTGCCACCCAGGAGGTGGTGACGCAGCTGCAGAGCCAGATCTTGGAGCTGCAGGGG GAGCTGAAGGAGTTTAAAACTTGTAATAAGCAACTTCACCAAAAGTTAATTCTGGCTGAAGCAGTGATGGAGGGGAGGCCAACGCCCGACAAAACGTTGC TGAATGCTCAGCCCCCTGTGGGAGCAGCCTACCAGGACAGCCCAGGAGAGCAGAAAGGAATTAAAACCACATCTTCTGTCTGGAGAGACAAGGAAATGGA CAGTGATCAGCAAAGAAGCTACGAGATTGACTCTGAGATTTGCCCACCTGATGACCTTGCCAGCTTGCCATCATGCAAAGAAAATCCTGAAGATGTTCTG AGCCCAACTTCAGTAGCTACTTACCTGAGTTCCAAGAGTCAGCCTTCTGCTAAAGTCAGTGTGATGGGGACTGATCAGTCAGAGAGCATTAATACCTCAA ATGAGACAGAATACTTAAAACAGAAAATCCATGACTTGGAAACTGAGCTGGAAGGCTACCAGAATTTCATATTTCAGCTTCAAAAGCACTCCCAGTGCAG TGAGGCCATAATTACAGTTTTGTGTGGGACAGAAGGGGCCCAGGATGGCTTGAGCAAGCCCAAGAATGGTTCTGATGGGGAAGAAATGACCTTTTCAAGT TTGCACCAAGTGCGATACGTGAAACACGTGAAAATCCTCGGTCCGCTGGCCCCAGAGATGATTGACAGCAGGGTGCTGGAGAACCTCAAACAGCAGCTGG AGGAACAGGAATACAAGCTGCAGAAGGAGCAGAATTTGAACATGCAACTTTTCAGTGAGATCCATAATCTGCAGAATAAGTTCAGAGATCTCTCACCTCC CAGATACGATTCATTAGTTCAGTCCCAAGCCAGGGAGCTCTCCCTTCAACGGCAGCAGATTAAGGATGGCCATGGCATCTGTGTCATCTCCCGTCAACAC ATGAACACCATGATTAAGGCATTTGAGGAGTTGCTGCAGGCCAGTGATGTGGATTACTGTGTGGCCGAGGGTTTCCAGGAACAGCTGAATCAATGTGCTG AGCTGCTGGAGAAATTGGAAAAGCTATTTCTCAACGGAAAATCAGTTGGAGTGGAAATGAACACCCAGAATGAACTGATGGAGAGGATTGAGGAAGACAA CTTAACCTACCAACATCTTCTGCCTGAATCTCCTGAGCCTTCAGCCTCTCATGCGCTCTCTGATTATGAAACATCTGAAAAGTCCTTCTTCTCACGAGAC CAGAAGCAAGATAATGAGACAGAGAAGACTTCAGTTATGGTGAACAGTTTTTCTCAAGACTTACTAATGGAACACATACAGGAAATTCGAACTTTGAGAA AGCGTTTAGAAGAATCTATTAAAACAAATGAGAAGCTACGGAAACAGTTGGAACGGCAAGGATCTGAATTTGTTCAAGGTTCTACAAGCATTTTTGCTTC TGGTTCAGAGCTTCATAGTTCTCTAACATCAGAAATTCATTTCTTGAGGAAGCAGAACCAGGCCCTCAATGCAATGCTCATTAAAGGATCCAGAGATAAA CAGAAGGAGAATGACAAATTACGAGAGTCCCTCTCCAGGAAGACCGTGAGCCTGGAGCACCTTCAGCGGGAGTATGCCAGCGTGAAGGAAGAAAATGAAA GGCTGCAGAAAGAAGGCAGCGAGAAGGAGAGACACAACCAGCAGCTGATCCAGGAGGTCCGCTGCAGCGGCCAGGAGCTGAGCAGGGTGCAGGAGGAGGT GAAGTTGAGGCAGCAGCTGCTCTCACAGAATGACAAGCTATTGCAGTCTCTCCGAGTGGAGCTGAAGGCGTATGAGAAGCTGGATGAAGAGCACAGGAGA CTGAGAGAGGCGTCGGGAGAAGGCTGGAAGGGGCAGGATCCTTTCAGGGACCTGCACAGCCTCCTGATGGAGATCCAGGCTCTGCGCTTGCAACTAGAAA GGAGCATCGAAACCAGCAGCACTCTGCAGAGCAGGCTCAAGGAACAGCTGGCAAGGGGGGCAGAGAAGGCACAGGAAGGAGCCCTCACTCTGGCTGTCCA AGCCGTGTCCATCCCTGAGGTGCCCCTTCAGCCTGACAAACACGATGGTGACAAATATCCCATGGAAAGTGATAATTCATTTGATCTGTTTGATTCCTCC CAGGCAGTGACACCAAAATCAGTTTCAGAGACTCCTCCACTCTCTGGGAATGACACGGACTCCCTCTCCTGCGACAGTGGCAGTTCGGCAACTAGCACTC CGTGTGTGTCCCGCCTGGTCACTGGCCACCACCTGTGGGCCAGCAAGAATGGCCGCCATGTCCTGGGCCTGATTGAGGACTATGAGGCCCTGCTCAAACA GATCAGCCAGGGACAGAGGCTCCTTGCTGAAATGGACATTCAAACCCAAGAGGCTCCCAGCTCCACAAGTCAAGAGCTGGGAACAAAGGGTCCACACCCA GCACCACTGAGCAAGTTTGTGAGCAGTGTGAGCACGGCCAAGCTGACCCTGGAAGAGGCCTACAGGCGGCTGAAGCTTCTCTGGAGAGTCTCACTCCCCG AGGATGGCCAGTGCCCCCTTCACTGTGAGCAGATTGGAGAAATGAAGGCAGAGGTCACCAAACTACATAAAAAATTGTTTGAACAAGAAAAGAAGTTGCA AAACACCATGAAGCTTTTGCAGCTGAGCAAGCGCCAGGAAAAAGTCATCTTTGATCAATTGGTCGTAACCCACAAAATCCTTCGGAAGGCCAGAGGAAAC CTGGAGCTTAGGCCTGGGGGAGCCCATCCAGGAACATGCAGTCCCAGCAGACCAGGCTCCTGAGAAGAACTTTCAGCCAATAAAGCTTGTGCTTCCCCCA CCGAGCTCACGCTGTCTCTTTGTTCCAAGTGTGGTTCCTATTTATTGAGGAAGAAAGAGCTGTCTGGCCAAAGGAAATCTATTTTTTCCCTTCATGTTTT CTCTCTGAAAGTTGGCTTGAGAGTTGTTGTCAGAAAGGTGCAGGTGCTCCACAAACGGGTGGTAAAAAGGCCTCGAGCTCTTGGATGTTGTATTTCAGAT CAGGGGCAGGCACCGGAGTTGAGGCTGTGCGCCTTGGTGGGCTTCACGTCTTCCCCTGGATTTGCTTAGTACTCAGCCAGTGCCACAGTTTGAAGATTCT CATTAAATGATTCATTTCATTTCACCTTGA

refseq_CDK5RAP2.F1 (forward primer)
refseq_CDK5RAP2.R1 (reverse primer)
Single exon skipping

Frame 0

RKKRRERWRRLWFEFQRRRQSLNKSWGGGGGDL GSPAGRYRGGY*WRRRHRHQRCRHLCSHDGLGVG RGRHRPWDAQRLQWPCSQCTR*PGWHQPQCWVG KWSAPKCVRRNSVSHQSTEHEGL*KSNH*IEER KL*PKAPHLFP*GKNATGISWPH*TYLQN*H*AQ GGSRKSEAGTPGERAAAHQSLQSS*ELS*SRWL *NPAGERRCSKEGAAGGRSPN*KNTPFGKGCDS RPGRTGKGLCRDRDGEGSSVAFGKQAFRDEEDAR GGLGDGSGPG*ERQTD*GVEAVFEEQRSFNSVP *RGEISDGMS**ECVIWRAPRTLCCSKGRKGER N*GCTNGASEGEKQL*REDPGT*RGPEREGKRNC YREEK*SKEG*SHSGFNHGIKIKGKKG*RT*L* N*KAQCCLC*SQRGPTESTDPGISGV*RL*DCS IRKGSPFGCAALTKPHQEYREPQTA*KH*EDHPG AE*LAAGEGETGEGPGGSPSREEQRRLHHP*S* K*S*KITQ*SE*KRESNGKSLQESSE*KQ*KIA QSRASDQTSNRKYQSEGRVASEIQ*KRFGSNTAE LLFNGCRGS*AQE*RLNNRKVLFSTATRQQNHL L*GKETIIRL*RADSGLKERAGHLYPSGQISAG IRQYQQPAG*VKQDFCPAEATGAGCAFISEFAED LGGADQRNSEAGRRIIFTL**SNILSKYLP*RK QSVSSGTFFSRRT*EKGQ*PYTASEGAVYRQPA PEENHF*SLLHGFPGKWVSR*TCVYRTNRASG*Q GGRGHDQNWGG*RD*FPE*PAFAAE**DYERPF QRRLQKWILKAHGV*DFRL*WGPRTWLPRRRCI HKPACPFVQ*EGHIITGIQARPSESGTGTASGTT ILDRAGSFWRTP*W*N*EDT*AKR*TCTFCPNQ LIFQAT**TEVVL*GPASKGRRSAQGRTERCLS ADCGHGGRPAEIQA*SNKRGLGRETDQHCTQRRA SAREPARGAWVAGCPPFPPWYYQQRG*EVPLAN PNKTIPVIRKYVSSPCHPGGGDAAAEPDLGAAG GAEGV*NL**ATSPKVNSG*SSDGGEANARQNVA ECSAPCGSSLPGQPRRAERN*NHIFCLERQGNG Q*SAKKLRD*L*DLPT**PCQLAIMQRKS*RCS EPNFSSYLPEFQESAFC*SQCDGD*SVREH*YLK *DRILKTENP*LGN*AGRLPEFHISASKALPVQ *GHNYSFVWDRRGPGWLEQAQEWF*WGRNDLFK FAPSAIRETRENPRSAGPRDD*QQGAGEPQTAAG GTGIQAAEGAEFEHATFQ*DP*SAE*VQRSLTS QIRFISSVPSQGALPSTAAD*GWPWHLCHLPST HEHHD*GI*GVAAGQ*CGLLCGRGFPGTAESMC* AAGEIGKAISQRKISWSGNEHPE*TDGED*GRQ LNLPTSSA*IS*AFSLSCAL*L*NI*KVLLLTR PEAR**DREDFSYGEQFFSRLTNGTHTGNSNFEK AFRRIY*NK*EATETVGTARI*ICSRFYKHFCF WFRAS*FSNIRNSFLEEAEPGPQCNAH*RIQR* TEGE*QITRVPLQEDREPGAPSAGVCQREGRK*K AAERRQREGETQPAADPGGPLQRPGAEQGAGGG EVEAAAALTE*QAIAVSPSGAEGV*EAG*RAQE TERGVGRRLEGAGSFQGPAQPPDGDPGSALATRK EHRNQQHSAEQAQGTAGKGGREGTGRSPHSGCP SRVHP*GAPSA*QTRW*QISHGK**FI*SV*FL PGSDTKISFRDSSTLWE*HGLPLLRQWQFGN*HS VCVPPGHWPPPVGQQEWPPCPGPD*GL*GPAQT DQPGTEAPC*NGHSNPRGSQLHKSRAGNKGSTP STTEQVCEQCEHGQADPGRGLQAAEASLESLTPR GWPVPPSL*ADWRNEGRGHQTT*KIV*TRKEVA KHHEAFAAEQAPGKSHL*SIGRNPQNPSEGQRK PGA*AWGSPSRNMQSQQTRLLRRTFSQ*SLCFPH RAHAVSLFQVWFLFIEEERAVWPKEIYFFPSCF LSESWLESCCQKGAGAPQTGGKKASSSWMLYFR SGAGTGVEAVRLGGLHVFPWICLVLSQCHSLKIL IK*FISFHL

Frame 1

GRSAGKDGGVCGLNSSGAARV*TRAGVEGAGTW GARRVAIAGGTSGAAATDTNAVATSVAMMDLVL EEDVTVPGTLSGCSGLVPSVPDDLDGINPNAGLG NGLLPNVSEETVSPTRARNMKDFENQITELKKE NFNLKLRIYFLEERMQQEFHGPTEHIYKTNIEL KVEVESLKRELQEREQLLIKASKAVESLAEAGGS EIQRVKEDARKKVQQVEDLLTKRILLLEKDVTA AQAELEKAFAGTETEKALRLRLESKLSEMKKMH EGDLAMALVLDEKDRLIEELKLSLKSKEALIQCL KEEKSQMACPDENVSSGELRGLCAAPREEKERE TEAAQMEHQKERNSFEERIQALEEDLREKEREI ATEKKNSLKRDKAIQGLTMALKSKEKKVEELNSE IEKLSAAFAKAREALQKAQTQEFQGSEDYETAL SGKEALSAALRSQNLTKSTENHRLRRSIKKITQ ELSDLQQERERLEKDLEEAHREKSKGDCTIRDLR NEVEKLRNEVNEREKAMENRYKSLLSESNKKLH NQEQVIKHLTESTNQKDVLLQKFNEKDLEVIQQ NCYLMAAEDLELRSEGLITEKCSSQQPPGSKTIF SKEKKQSSDYEELIQVLKKEQDIYTHLVKSLQE SDSINNLQAELNKIFALRKQLEQDVLSYQNLRK TLEEQISEIRRREEESFSLYSDQTSYLSICLEEN NRFQVEHFSQEELKKKVSDLIQLVKELYTDNQH LKKTIFDLSCMGFQGNGFPDRLASTEQTELLAS KEDEDTIKIGEDDEINFLSDQHLQQSNEIMKDLS KGGCKNGYLRHTESKISDCDGAHAPGCLEEGAF INLLAPLFNEKATLLLESRPDLLKVVRELLLGQ LFLTEQEVSGEHLDGKTEKTPKQKGELVHFVQTN SFSKPHDELKLSCEAQLVKAGEVPKVGLKDASV QTVATEGDLLRFKHEATREAWEEKPINTALSAE HRPENLHGVPGWQAALLSLPGITNREAKKSRLPI LIKPSRSLGNMYRLPATQEVVTQLQSQILELQG ELKEFKTCNKQLHQKLILAEAVMEGRPTPDKTL LNAQPPVGAAYQDSPGEQKGIKTTSSVWRDKEMD SDQQRSYEIDSEICPPDDLASLPSCKENPEDVL SPTSVATYLSSKSQPSAKVSVMGTDQSESINTS NETEYLKQKIHDLETELEGYQNFIFQLQKHSQCS EAIITVLCGTEGAQDGLSKPKNGSDGEEMTFSS LHQVRYVKHVKILGPLAPEMIDSRVLENLKQQL EEQEYKLQKEQNLNMQLFSEIHNLQNKFRDLSPP RYDSLVQSQARELSLQRQQIKDGHGICVISRQH MNTMIKAFEELLQASDVDYCVAEGFQEQLNQCA ELLEKLEKLFLNGKSVGVEMNTQNELMERIEEDN LTYQHLLPESPEPSASHALSDYETSEKSFFSRD QKQDNETEKTSVMVNSFSQDLLMEHIQEIRTLR KRLEESIKTNEKLRKQLERQGSEFVQGSTSIFAS GSELHSSLTSEIHFLRKQNQALNAMLIKGSRDK QKENDKLRESLSRKTVSLEHLQREYASVKEENE RLQKEGSEKERHNQQLIQEVRCSGQELSRVQEEV KLRQQLLSQNDKLLQSLRVELKAYEKLDEEHRR LREASGEGWKGQDPFRDLHSLLMEIQALRLQLE RSIETSSTLQSRLKEQLARGAEKAQEGALTLAVQ AVSIPEVPLQPDKHDGDKYPMESDNSFDLFDSS QAVTPKSVSETPPLSGNDTDSLSCDSGSSATST PCVSRLVTGHHLWASKNGRHVLGLIEDYEALLKQ ISQGQRLLAEMDIQTQEAPSSTSQELGTKGPHP APLSKFVSSVSTAKLTLEEAYRRLKLLWRVSLP EDGQCPLHCEQIGEMKAEVTKLHKKLFEQEKKLQ NTMKLLQLSKRQEKVIFDQLVVTHKILRKARGN LELRPGGAHPGTCSPSRPGS*EELSANKACASP TELTLSLCSKCGSYLLRKKELSGQRKSIFSLHVF SLKVGLRVVVRKVQVLHKRVVKRPRALGCCISD QGQAPELRLCALVGFTSSPGFA*YSASATV*RF SLNDSFHFTL

Frame 2

EEAPGKMAASVV*IPAAPPESEQELGWRGRGPG EPGGSLSRGVLVAPPPQTPTLSPPL*P*WTWCW KRTSPSLGRSAAAVALFPVYQMTWMASTPMLGW EMVCSQMCQKKQCLPPEHGT*RTLKIKSLN*RKK TLT*SSASISLRKECNRNFMAPLNISTKLTLSS RWK*KV*SGNSRRESSCSSKPPKQLRA*LKQVA LKSSG*KKMLERRCSRWKIS*LKEYSFWKRM*QP PRQNWKRPLQGQRRRRLFGCVWKASFQR*RRCT RGTWRWLWSWMRKTD*LRS*SCL*RAKKL*FSA LKRRNLRWHVLMRMCHLESSEDFVLLQGKKRREK LRLHKWSIRRRETALKRGSRHLKRT*ERRKEKL LQRRKIV*RGIKPFRV*PWH*NQRKKRLKNLTL KLKSSVLPLLKPERPYRKHRPRNFRGLKTMRLLY QERKPFRLRCAHKTSPRVQRTTDCVEALRRSPR S*VTCSRRGRDWRRTWRKPIERRAKETAPSVIL EMKLKNYAMK*MKERKQWKIVTRVF*VKAIKNCT IKSK*SNI*QKVPIRRTCCFRNSMKKIWK*YSR TAI*WLQRILSSGVKA**QKSALLNSHQAAKPS SLRKRNNHQTMKS*FRS*RKSRTSIPIWSNLCRN QTVSTTCRLS*TRFLPCGSNWSRMCFHIRICGR PWRSRSAKFGGGKKNHFHFIVIKHLI*VFALKK TIGFKWNIFLKKNLRKRSVTLYS**RSCIQTTST *RKPFLISPAWVSREMGFQIDLRLQNKQSFWLA RRTRTRSKLGRMTRLIS*VTSICSRVMRL*KTF PKEAAKMDT*GTRSLRFQIVMGPTHLAA*KKVHS *TCLPLCSMRRPHYYWNPGQTF*KWYGNCFWDN YS*QSRKFLENTLMVKLRRHLSKKVNLYILSKP THFPSHMMN*SCLVRPS**RQAKCPR*D*KMPQC RLWPRRATC*DSSMKQQERLGKRNRSTLHSAQS IGQRTCTGCLGGRLPSFPSLVLPTERLRSPACQ S**NHPGH*EICIVSLPPRRW*RSCRARSWSCRG S*RSLKLVISNFTKS*FWLKQ*WRGGQRPTKRC *MLSPLWEQPTRTAQESRKELKPHLLSGETRKW TVISKEATRLTLRFAHLMTLPACHHAKKILKMF* AQLQ*LLT*VPRVSLLLKSV*WGLISQRALIPQ MRQNT*NRKSMTWKLSWKATRISYFSFKSTPSA VRP*LQFCVGQKGPRMA*ASPRMVLMGKK*PFQV CTKCDT*NT*KSSVRWPQR*LTAGCWRTSNSSW RNRNTSCRRSRI*TCNFSVRSIICRISSEISHL PDTIH*FSPKPGSSPFNGSRLRMAMASVSSPVNT *TP*LRHLRSCCRPVMWITVWPRVSRNS*INVL SCWRNWKSYFSTENQLEWK*TPRMN*WRGLRKT T*PTNIFCLNLLSLQPLMRSLIMKHLKSPSSHET RSKIMRQRRLQLW*TVFLKTY*WNTYRKFEL*E SV*KNLLKQMRSYGNSWNGKDLNLFKVLQAFLL LVQSFIVL*HQKFIS*GSRTRPSMQCSLKDPEIN RRRMTNYESPSPGRP*AWSTFSGSMPA*RKKMK GCRKKAARRRDTTSS*SRRSAAAARS*AGCRRR *S*GSSCSHRMTSYCSLSEWS*RRMRSWMKSTGD *ERRREKAGRGRILSGTCTAS*WRSRLCACN*K GASKPAALCRAGSRNSWQGGQRRHRKEPSLWLS KPCPSLRCPFSLTNTMVTNIPWKVIIHLICLIPP RQ*HQNQFQRLLHSLGMTRTPSPATVAVRQLAL RVCPAWSLATTCGPARMAAMSWA*LRTMRPCSN RSARDRGSLLKWTFKPKRLPAPQVKSWEQRVHTQ HH*ASL*AV*ARPS*PWKRPTGG*SFSGESHSP RMASAPFTVSRLEK*RQRSPNYIKNCLNKKRSC KTP*SFCS*ASARKKSSLINWS*PTKSFGRPEET WSLGLGEPIQEHAVPADQAPEKNFQPIKLVLPP PSSRCLFVPSVVPIY*GRKSCLAKGNLFFPFMF SL*KLA*ELLSERCRCSTNGW*KGLELLDVVFQI RGRHRS*GCAPWWASRLPLDLLSTQPVPQFEDS H*MIHFISP*