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Sequences

Sequence NM_025021

CCAGCCGGCGCTTGCGCGGTGGCACGGGCGAGTGGGGGGGCGAGGAGGTGGAGGAGGAGGAGGAGGAGGAGGAGGTGGCGGCGAGAAGATGGCGACTTCG AACAATCCGCGGAAATTCAGCGAGAAGATCGCGCTGCACAATCAGAAGCAGGCGGAGGAGACGGCGGCCTTCGAGGAGGTCATGAAGGACCTGAGCCTGA CGCGGGCCGCGCGGCTCCAGCTCCAGAAATCCCAGTACCTGCAACTGGGCCCCAGCCGAGGCCAGTACTATGGCGGGTCCCTGCCCAACGTGAACCAGAT CGGGAGTGGCACCATGGACCTGCCCTTCCAGACCCCCTTCCAATCCTCGGGCCTGGACACCAGCCGGACCACCCGGCACCATGGGCTGGTGGACAGGGTG TACCGGGAGCGTGGCCGGCTCGGCTCCCCACACCGCCGGCCCCTGTCAGTGGACAAACACGGACGGCAGGCCGACAGCTGCCCCTATGGCACCATGTACC TCTCACCACCCGCGGACACCAGCTGGAGAAGGACCAATTCTGACTCCGCCCTGCACCAGAGCACAATGACGCCCACGCAGCCAGAATCCTTTAGCAGTGG GTCCCAGGACGTGCACCAGAAAAGAGTCTTACTGTTAACAGTCCCAGGAATGGAAGAGACCACATCAGAGGCAGACAAAAACCTTTCCAAGCAAGCATGG GACACCAAGAAGACGGGGTCCAGGCCCAAGTCCTGTGAGGTCCCCGGAATCAACATCTTCCCGTCTGCCGACCAGGAAAACACTACAGCCCTGATCCCCG CCACCCACAACACAGGGGGGTCCCTGCCCGACCTGACCAACATCCACTTCCCCTCCCCGCTCCCGACCCCGCTGGACCCCGAGGAGCCCACCTTCCCTGC ACTGAGCAGCTCCAGCAGCACCGGCAACCTCGCGGCCAACCTGACGCACCTGGGCATCGGTGGCGCCGGCCAGGGAATGAGCACACCTGGCTCCTCTCCA CAGCACCGCCCAGCTGGCGTCAGCCCCCTGTCCCTGAGCACAGAGGCAAGGCGTCAGCAGGCATCGCCCACCCTGTCCCCGCTGTCACCCATCACTCAGG CTGTAGCCATGGACGCCCTGTCTCTGGAGCAGCAGCTGCCCTACGCCTTCTTCACCCAGGCGGGCTCCCAGCAGCCACCGCCGCAGCCCCAGCCCCCGCC GCCTCCTCCACCCGCGTCCCAGCAGCCACCACCCCCGCCACCCCCACAGGCGCCCGTCCGCCTGCCCCCTGGTGGCCCCCTGTTGCCCAGCGCCAGCCTG ACTCGTGGGCCACAGCCGCCCCCGCTTGCAGTCACGGTACCGTCCTCTCTCCCCCAGTCCCCCCCAGAGAACCCTGGCCAGCCATCGATGGGGATCGACA TCGCCTCGGCGCCGGCTCTGCAGCAGTACCGCACTAGCGCCGGCTCCCCGGCCAACCAGTCTCCCACCTCGCCAGTCTCCAATCAAGGCTTCTCCCCAGG GAGCTCCCCGCAACTGGAGCAGTTCAACATGATGGAGAACGCCATCAGCTCCAGCAGCCTGTACAGCCCGGGCTCCACACTCAACTACTCGCAGGCGGCC ATGATGGGCCTCACGGGCAGCCACGGGAGCCTGCCGGACTCGCAGCAACTGGGATACGCCAGCCACAGTGGCATCCCCAACATCATCCTCACAGTGACAG GAGAGTCCCCCCCCAGCCTCTCTAAAGAACTGACCAGCCACCGAGGACACCTTCCGGATGGACCGCCTGTGAGCGGGCACGCCGGCACCCTGCCGCTCAG CCGTCCCGACGGCGCCTCCCCAGCCCGGGGACGGCCGTGCTCCGTCCCTCGCCAACGGCCGAGCTTGTGATTCTGAGCTTGCAATGCCGCCAAGCGCCCC CCGCCAGCCCGCCCCCGGTTGTCCACCTCCCGCGAAGCCCAATCGCGAGGCCGCGAGCCGGGCCGTCCACCCACCCGCCCGCCCAGGGCTGGGCTGGGAT CGGAGGCCGTGAGCCTCCCGCCCCTGCAGACCCTCCCTGCACTGGCTCCCTCGCCCCCAGCCCCGGGGCCTGAGCCGTCCCCTGTAAGATGCGGGAAGTG TCAGCTCCCGGCGTGGCGGGCAGGCTCAGGGGAGGGGCGCGCATGGTCCGCCAGGGCTGTGGGCCGTGGCGCATTTTCCGACTGTTTGTCCAGCTCTCAC TGCCTTCCTTGGTTCCCGGTCCCCCAGCCCATCCGCCATCCCCAGCCCGTGGTCAGGTAGAGAGTGAGCCCCACGCCGCCCCAGGGAGGAGGCGCCAGAG CGCGGGGCAGACGCAAAGTGAAATAAACACTATTTTGACGGC

refseq_CRTC1.F2 (forward primer)
refseq_CRTC1.R2 (reverse primer)
Single exon skipping

Frame 0

PAGACAVARASGGARRWRRRRRRRRWRREDGDF EQSAEIQREDRAAQSEAGGGDGGLRGGHEGPEPD AGRAAPAPEIPVPATGPQPRPVLWRVPAQREPD REWHHGPALPDPLPILGPGHQPDHPAPWAGGQG VPGAWPARLPTPPAPVSGQTRTAGRQLPLWHHVP LTTRGHQLEKDQF*LRPAPEHNDAHAARIL*QW VPGRAPEKSLTVNSPRNGRDHIRGRQKPFQASM GHQEDGVQAQVL*GPRNQHLPVCRPGKHYSPDPR HPQHRGVPARPDQHPLPLPAPDPAGPRGAHLPC TEQLQQHRQPRGQPDAPGHRWRRPGNEHTWLLS TAPPSWRQPPVPEHRGKASAGIAHPVPAVTHHSG CSHGRPVSGAAAALRLLHPGGLPAATAAAPAPA ASSTRVPAATTPATPTGARPPAPWWPPVAQRQP DSWATAAPACSHGTVLSPPVPPREPWPAIDGDRH RLGAGSAAVPH*RRLPGQPVSHLASLQSRLLPR ELPATGAVQHDGERHQLQQPVQPGLHTQLLAGG HDGPHGQPREPAGLAATGIRQPQWHPQHHPHSDR RVPPQPL*RTDQPPRTPSGWTACERARRHPAAQ PSRRRLPSPGTAVLRPSPTAELVILSLQCRQAP PASPPPVVHLPRSPIARPRAGPSTHPPAQGWAGI GGREPPAPADPPCTGSLAPSPGA*AVPCKMREV SAPGVAGRLRGGARMVRQGCGPWRIFRLFVQLS LPSLVPGPPAHPPSPARGQVESEPHAAPGRRRQS AGQTQSEINTILT

Frame 1

QPALARWHGRVGGRGGGGGGGGGGGGGEKMATS NNPRKFSEKIALHNQKQAEETAAFEEVMKDLSL TRAARLQLQKSQYLQLGPSRGQYYGGSLPNVNQI GSGTMDLPFQTPFQSSGLDTSRTTRHHGLVDRV YRERGRLGSPHRRPLSVDKHGRQADSCPYGTMY LSPPADTSWRRTNSDSALHQSTMTPTQPESFSSG SQDVHQKRVLLLTVPGMEETTSEADKNLSKQAW DTKKTGSRPKSCEVPGINIFPSADQENTTALIP ATHNTGGSLPDLTNIHFPSPLPTPLDPEEPTFPA LSSSSSTGNLAANLTHLGIGGAGQGMSTPGSSP QHRPAGVSPLSLSTEARRQQASPTLSPLSPITQ AVAMDALSLEQQLPYAFFTQAGSQQPPPQPQPPP PPPPASQQPPPPPPPQAPVRLPPGGPLLPSASL TRGPQPPPLAVTVPSSLPQSPPENPGQPSMGID IASAPALQQYRTSAGSPANQSPTSPVSNQGFSPG SSPQLEQFNMMENAISSSSLYSPGSTLNYSQAA MMGLTGSHGSLPDSQQLGYASHSGIPNIILTVT GESPPSLSKELTSHRGHLPDGPPVSGHAGTLPLS RPDGASPARGRPCSVPRQRPSL*F*ACNAAKRP PPARPRLSTSREAQSRGREPGRPPTRPPRAGLG SEAVSLPPLQTLPALAPSPPAPGPEPSPVRCGKC QLPAWRAGSGEGRAWSARAVGRGAFSDCLSSSH CLPWFPVPQPIRHPQPVVR*RVSPTPPQGGGAR ARGRRKVK*TLF*R

Frame 2

SRRLRGGTGEWGGEEVEEEEEEEEVAARRWRLR TIRGNSARRSRCTIRSRRRRRRPSRRS*RT*A* RGPRGSSSRNPSTCNWAPAEASTMAGPCPT*TR SGVAPWTCPSRPPSNPRAWTPAGPPGTMGWWTGC TGSVAGSAPHTAGPCQWTNTDGRPTAAPMAPCT SHHPRTPAGEGPILTPPCTRAQ*RPRSQNPLAV GPRTCTRKESYC*QSQEWKRPHQRQTKTFPSKHG TPRRRGPGPSPVRSPESTSSRLPTRKTLQP*SP PPTTQGGPCPT*PTSTSPPRSRPRWTPRSPPSL H*AAPAAPATSRPT*RTWASVAPARE*AHLAPLH STAQLASAPCP*AQRQGVSRHRPPCPRCHPSLR L*PWTPCLWSSSCPTPSSPRRAPSSHRRSPSPR RLLHPRPSSHHPRHPHRRPSACPLVAPCCPAPA* LVGHSRPRLQSRYRPLSPSPPQRTLASHRWGST SPRRRLCSSTALAPAPRPTSLPPRQSPIKASPQ GAPRNWSSST*WRTPSAPAACTARAPHSTTRRRP *WASRAATGACRTRSNWDTPATVASPTSSSQ*Q ESPPPASLKN*PATEDTFRMDRL*AGTPAPCRS AVPTAPPQPGDGRAPSLANGRACDSELAMPPSAP RQPAPGCPPPAKPNREAASRAVHPPARPGLGWD RRP*ASRPCRPSLHWLPRPQPRGLSRPL*DAGS VSSRRGGQAQGRGAHGPPGLWAVAHFPTVCPALT AFLGSRSPSPSAIPSPWSGRE*APRRPREEAPE RGADAK*NKHYFDG

Sequence NM_015321

CCAGCCGGCGCTTGCGCGGTGGCACGGGCGAGTGGGGGGGCGAGGAGGTGGAGGAGGAGGAGGAGGAGGAGGAGGTGGCGGCGAGAAGATGGCGACTTCG AACAATCCGCGGAAATTCAGCGAGAAGATCGCGCTGCACAATCAGAAGCAGGCGGAGGAGACGGCGGCCTTCGAGGAGGTCATGAAGGACCTGAGCCTGA CGCGGGCCGCGCGGCTCCAGCTCCAGAAATCCCAGTACCTGCAACTGGGCCCCAGCCGAGGCCAGTACTATGGCGGGTCCCTGCCCAACGTGAACCAGAT CGGGAGTGGCACCATGGACCTGCCCTTCCAGACCCCCTTCCAATCCTCGGGCCTGGACACCAGCCGGACCACCCGGCACCATGGGCTGGTGGACAGGGTG TACCGGGAGCGTGGCCGGCTCGGCTCCCCACACCGCCGGCCCCTGTCAGTGGACAAACACGGACGGCAGGCCGACAGCTGCCCCTATGGCACCATGTACC TCTCACCACCCGCGGACACCAGCTGGAGAAGGACCAATTCTGACTCCGCCCTGCACCAGAGCACAATGACGCCCACGCAGCCAGAATCCTTTAGCAGTGG GTCCCAGGACGTGCACCAGAAAAGAGTCTTACTGTTAACAGTCCCAGGAATGGAAGAGACCACATCAGAGGCAGACAAAAACCTTTCCAAGCAAGCATGG GACACCAAGAAGACGGGGTCCAGGCCCAAGTCCTGTGAGGTCCCCGGAATCAACATCTTCCCGTCTGCCGACCAGGAAAACACTACAGCCCTGATCCCCG CCACCCACAACACAGGGGGGTCCCTGCCCGACCTGACCAACATCCACTTCCCCTCCCCGCTCCCGACCCCGCTGGACCCCGAGGAGCCCACCTTCCCTGC ACTGAGCAGCTCCAGCAGCACCGGCAACCTCGCGGCCAACCTGACGCACCTGGGCATCGGTGGCGCCGGCCAGGGAATGAGCACACCTGGCTCCTCTCCA CAGCACCGCCCAGCTGGCGTCAGCCCCCTGTCCCTGAGCACAGAGGCAAGGCGTCAGCAGGCATCGCCCACCCTGTCCCCGCTGTCACCCATCACTCAGG CTGTAGCCATGGACGCCCTGTCTCTGGAGCAGCAGCTGCCCTACGCCTTCTTCACCCAGGCGGGCTCCCAGCAGCCACCGCCGCAGCCCCAGCCCCCGCC GCCTCCTCCACCCGCGTCCCAGCAGCCACCACCCCCGCCACCCCCACAGGCGCCCGTCCGCCTGCCCCCTGGTGGCCCCCTGTTGCCCAGCGCCAGCCTG ACTCGTGGGCCACAGCCGCCCCCGCTTGCAGTCACGGTACCGTCCTCTCTCCCCCAGTCCCCCCCAGAGAACCCTGGCCAGCCATCGATGGGGATCGACA TCGCCTCGGCGCCGGCTCTGCAGCAGTACCGCACTAGCGCCGGCTCCCCGGCCAACCAGTCTCCCACCTCGCCAGTCTCCAATCAAGGCTTCTCCCCAGG GAGCTCCCCGCAACACACTTCCACCCTGGGCAGCGTGTTTGGGGACGCGTACTATGAGCAGCAGATGGCGGCCAGGCAGGCCAATGCTCTGTCCCACCAG CTGGAGCAGTTCAACATGATGGAGAACGCCATCAGCTCCAGCAGCCTGTACAGCCCGGGCTCCACACTCAACTACTCGCAGGCGGCCATGATGGGCCTCA CGGGCAGCCACGGGAGCCTGCCGGACTCGCAGCAACTGGGATACGCCAGCCACAGTGGCATCCCCAACATCATCCTCACAGTGACAGGAGAGTCCCCCCC CAGCCTCTCTAAAGAACTGACCAGCTCTCTGGCCGGGGTCGGCGACGTCAGCTTCGACTCCGACAGCCAGTTTCCCCTGGACGAACTCAAGATCGACCCC CTGACCCTCGACGGACTGCACATGCTCAACGACCCCGACATGGTTCTGGCCGACCCAGCCACCGAGGACACCTTCCGGATGGACCGCCTGTGAGCGGGCA CGCCGGCACCCTGCCGCTCAGCCGTCCCGACGGCGCCTCCCCAGCCCGGGGACGGCCGTGCTCCGTCCCTCGCCAACGGCCGAGCTTGTGATTCTGAGCT TGCAATGCCGCCAAGCGCCCCCCGCCAGCCCGCCCCCGGTTGTCCACCTCCCGCGAAGCCCAATCGCGAGGCCGCGAGCCGGGCCGTCCACCCACCCGCC CGCCCAGGGCTGGGCTGGGATCGGAGGCCGTGAGCCTCCCGCCCCTGCAGACCCTCCCTGCACTGGCTCCCTCGCCCCCAGCCCCGGGGCCTGAGCCGTC CCCTGTAAGATGCGGGAAGTGTCAGCTCCCGGCGTGGCGGGCAGGCTCAGGGGAGGGGCGCGCATGGTCCGCCAGGGCTGTGGGCCGTGGCGCATTTTCC GACTGTTTGTCCAGCTCTCACTGCCTTCCTTGGTTCCCGGTCCCCCAGCCCATCCGCCATCCCCAGCCCGTGGTCAGGTAGAGAGTGAGCCCCACGCCGC CCCAGGGAGGAGGCGCCAGAGCGCGGGGCAGACGCAAAGTGAAATAAACACTATTTTGA

refseq_CRTC1.F2 (forward primer)
refseq_CRTC1.R2 (reverse primer)
Single exon skipping

Frame 0

PAGACAVARASGGARRWRRRRRRRRWRREDGDF EQSAEIQREDRAAQSEAGGGDGGLRGGHEGPEPD AGRAAPAPEIPVPATGPQPRPVLWRVPAQREPD REWHHGPALPDPLPILGPGHQPDHPAPWAGGQG VPGAWPARLPTPPAPVSGQTRTAGRQLPLWHHVP LTTRGHQLEKDQF*LRPAPEHNDAHAARIL*QW VPGRAPEKSLTVNSPRNGRDHIRGRQKPFQASM GHQEDGVQAQVL*GPRNQHLPVCRPGKHYSPDPR HPQHRGVPARPDQHPLPLPAPDPAGPRGAHLPC TEQLQQHRQPRGQPDAPGHRWRRPGNEHTWLLS TAPPSWRQPPVPEHRGKASAGIAHPVPAVTHHSG CSHGRPVSGAAAALRLLHPGGLPAATAAAPAPA ASSTRVPAATTPATPTGARPPAPWWPPVAQRQP DSWATAAPACSHGTVLSPPVPPREPWPAIDGDRH RLGAGSAAVPH*RRLPGQPVSHLASLQSRLLPR ELPATHFHPGQRVWGRVL*AADGGQAGQCSVPP AGAVQHDGERHQLQQPVQPGLHTQLLAGGHDGPH GQPREPAGLAATGIRQPQWHPQHHPHSDRRVPP QPL*RTDQLSGRGRRRQLRLRQPVSPGRTQDRP PDPRRTAHAQRPRHGSGRPSHRGHLPDGPPVSGH AGTLPLSRPDGASPARGRPCSVPRQRPSL*F*A CNAAKRPPPARPRLSTSREAQSRGREPGRPPTR PPRAGLGSEAVSLPPLQTLPALAPSPPAPGPEPS PVRCGKCQLPAWRAGSGEGRAWSARAVGRGAFS DCLSSSHCLPWFPVPQPIRHPQPVVR*RVSPTP PQGGGARARGRRKVK*TLF*

Frame 1

QPALARWHGRVGGRGGGGGGGGGGGGGEKMATS NNPRKFSEKIALHNQKQAEETAAFEEVMKDLSL TRAARLQLQKSQYLQLGPSRGQYYGGSLPNVNQI GSGTMDLPFQTPFQSSGLDTSRTTRHHGLVDRV YRERGRLGSPHRRPLSVDKHGRQADSCPYGTMY LSPPADTSWRRTNSDSALHQSTMTPTQPESFSSG SQDVHQKRVLLLTVPGMEETTSEADKNLSKQAW DTKKTGSRPKSCEVPGINIFPSADQENTTALIP ATHNTGGSLPDLTNIHFPSPLPTPLDPEEPTFPA LSSSSSTGNLAANLTHLGIGGAGQGMSTPGSSP QHRPAGVSPLSLSTEARRQQASPTLSPLSPITQ AVAMDALSLEQQLPYAFFTQAGSQQPPPQPQPPP PPPPASQQPPPPPPPQAPVRLPPGGPLLPSASL TRGPQPPPLAVTVPSSLPQSPPENPGQPSMGID IASAPALQQYRTSAGSPANQSPTSPVSNQGFSPG SSPQHTSTLGSVFGDAYYEQQMAARQANALSHQ LEQFNMMENAISSSSLYSPGSTLNYSQAAMMGL TGSHGSLPDSQQLGYASHSGIPNIILTVTGESPP SLSKELTSSLAGVGDVSFDSDSQFPLDELKIDP LTLDGLHMLNDPDMVLADPATEDTFRMDRL*AG TPAPCRSAVPTAPPQPGDGRAPSLANGRACDSEL AMPPSAPRQPAPGCPPPAKPNREAASRAVHPPA RPGLGWDRRP*ASRPCRPSLHWLPRPQPRGLSR PL*DAGSVSSRRGGQAQGRGAHGPPGLWAVAHFP TVCPALTAFLGSRSPSPSAIPSPWSGRE*APRR PREEAPERGADAK*NKHYF

Frame 2

SRRLRGGTGEWGGEEVEEEEEEEEVAARRWRLR TIRGNSARRSRCTIRSRRRRRRPSRRS*RT*A* RGPRGSSSRNPSTCNWAPAEASTMAGPCPT*TR SGVAPWTCPSRPPSNPRAWTPAGPPGTMGWWTGC TGSVAGSAPHTAGPCQWTNTDGRPTAAPMAPCT SHHPRTPAGEGPILTPPCTRAQ*RPRSQNPLAV GPRTCTRKESYC*QSQEWKRPHQRQTKTFPSKHG TPRRRGPGPSPVRSPESTSSRLPTRKTLQP*SP PPTTQGGPCPT*PTSTSPPRSRPRWTPRSPPSL H*AAPAAPATSRPT*RTWASVAPARE*AHLAPLH STAQLASAPCP*AQRQGVSRHRPPCPRCHPSLR L*PWTPCLWSSSCPTPSSPRRAPSSHRRSPSPR RLLHPRPSSHHPRHPHRRPSACPLVAPCCPAPA* LVGHSRPRLQSRYRPLSPSPPQRTLASHRWGST SPRRRLCSSTALAPAPRPTSLPPRQSPIKASPQ GAPRNTLPPWAACLGTRTMSSRWRPGRPMLCPTS WSSST*WRTPSAPAACTARAPHSTTRRRP*WAS RAATGACRTRSNWDTPATVASPTSSSQ*QESPP PASLKN*PALWPGSATSASTPTASFPWTNSRSTP *PSTDCTCSTTPTWFWPTQPPRTPSGWTACERA RRHPAAQPSRRRLPSPGTAVLRPSPTAELVILS LQCRQAPPASPPPVVHLPRSPIARPRAGPSTHPP AQGWAGIGGREPPAPADPPCTGSLAPSPGA*AV PCKMREVSAPGVAGRLRGGARMVRQGCGPWRIF RLFVQLSLPSLVPGPPAHPPSPARGQVESEPHAA PGRRRQSAGQTQSEINTIL