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Sequences

Sequence NM_012095

CCTGAATCTAGATGGAGAGAAACCCACCATTTTTCTAGGCCCTGGATTATGTAGAAGATTTAGATACTAAGCCTCAAGAGACGTCTTTCCTCTCATTTAC
GGTCTTCCTGC
ATATTTAAAATTTCTAATACGGTAGACAGAGTCGGTGTCTTTGAAGCTGTTAATCAGGCAATTTCCTGGGCACTCCAGCTGCGGGTCCT
CGCGGCCTTCTCGGCTTCTCCAGCTTCGGTAGGAGAGGATCCGGCGCCGAATCACTGACTGGCACAGGTGTTGGGAAAATGATCCACAGTCTATTTCTCA
TAAACTGTTCCGGTGACATATTTCTAGAGAAGCACTGGAAGAGCGTTGTGAGCCAGTCTGTCTGTGATTATTTCTTTGAAGCTCAAGAGAAAGCTGCTGA
TGTTGAAAATGTACCACCTGTCATTTCAACACCTCACCACTACCTCATCAGTATCTACCGGGATAAGCTCTTCTTTGTATCTGTCATACAGACCGAAGTG
CCACCTCTCTTTGTAATTGAGTTCCTACATCGAGTTGCTGACACTTTTCAGGACTACTTTGGTGAGTGTTCAGAGGCTGCAATTAAGGATAATGTGGTCA
TAGTATATGAACTCTTAGAAGAAATGTTAGACAATGGATTTCCACTGGCTACCGAATCTAACATTTTGAAAGAATTGATTAAACCACCAACAATTCTACG
CTCTGTTGTCAACTCTATTACAGGCAGTAGTAATGTTGGGGACACACTCCCCACCGGGCAGCTGTCCAACATACCATGGCGTCGGGCAGGGGTAAAGTAC
ACAAACAATGAAGCCTATTTTGATGTTGTTGAAGAAATAGACGCAATTATAGATAAATCAGGATCTACAGTCTTTGCAGAAATTCAGGGGGTCATTGATG
CTTGCATTAAACTATCTGGAATGCCTGATCTCTCCCTTTCTTTCATGAACCCTAGGCTTCTGGATGATGTCAGCTTTCACCCCTGCATCCGGTTCAAGCG
TTGGGAATCTGAAAGAGTTTTGTCATTTATTCCTCCAGATGGAAATTTCCGACTCATATCATACCGTGTCAGCTCACAAAATCTAGTGGCAATACCAGTG
TATGTGAAACATAGTATCAGCTTTAAGGAGAACAGTTCTTGCGGCAGATTTGATATAACAATTGGACCAAAGCAGAATATGGGGAAAACTATTGAAGGAA
TTACAGTGACAGTTCACATGCCAAAAGTTGTGCTGAACATGAACCTGACACCCACACAAGGCAGCTATACATTTGATCCAGTCACCAAGGTACTAACATG
GGATGTGGGAAAAATTACTCCACAAAAGCTCCCAAGTCTTAAAGGACTGGTAAATTTACAGTCTGGAGCCCCCAAACCAGAAGAGAATCCGAGCCTCAAC
ATACAGTTTAAGATCCAGCAGCTTGCTATTTCAGGCTTAAAAGTAAACCGTTTGGACATGTATGGGGAGAAATATAAGCCATTTAAAGGAGTCAAATACG
TCACGAAAGCTGGAAAGTTCCAAGTGAGGACATGAGAAGAGGCCAAAATTCCTCAGGACCAGTTTGTTTTCCAAGTGTCATTACGATGTATCACTATTAG
GTACCAAGTGAGTGGGAATACATATTCTAGTTAAAGCATTTGTGTCTAGCTACACACCGCTAACAAAGTTACTTAGTTATCAATGTAGGATTCTTAAGGA
GCTTTAAGCTAAGGAAACCTTTTAGTGACTTAGCTTATTTTGTATCTTTTCACTTAGGAAGATTTTGGAGGTGATTTTTTTCCATAGGAGGATACCATCT
GGCGGCTGCACATTGTAACAGTAAAGGCAGAAAGCTGTAGTGATAACCTCTCTCCTAAAAGAGTTAACTGGTCTCATCCAGCAGAAGCTATCTTAAATCT
GTGATGTGTCAGGTGCAGCCAAATATCACACCTTCTGATCTTAGCCATCCCAAACCAGTATCTGTCCCGAGAGGAAATTCCCCCCACCCCCAGAAGTTTA
CAGAAAACTGCCTCTTCAAGTGTTTGCCTTATTCAGCTTTTCACTTGTGCCATTAAGCAAGCACTGTAGCAAAAGCCACTTCCACATGGCCCTGGCAGGG
AGCACTGCTGCTCCATGCTCCATTCTCACTGTACTTGGTATTGTATTTTTTATAAATAAGATTTTTATGTAAAGCTTAGAATTTGATTTACAGGGACCTT
GCTGCAGTAAATACCATCTCAATTTTGTGCCACTGGTTCAGCTGTTAGCACAGTAAAAAAATCATTTGTATCAAAGGGGCAAATGCTTTATTAAGGTAGT
AAAAGGGAACATTACTTCTGCTTTTAGGAAGTTACTGCAAGCACAAGCATTTGTGCTTTTAAGCAAATTAAAGTAGTAAAAGAAAAACTTAAGTGAAACC
TTTGCCATCTTCATGTTTTATAATATAAAGCTTACCCAACACCAGTTAAGCCATGGTTAACCTAAATGCCTCATGCCCCAGTTCAGCAAAAGGAGGAAAA
TGTGCCTGCCTCACAGTCATCAGTCTTTTTAAATCTTTTTTGTTGTTGTTCTTAAGGGTTTGAATTTGTCTGCATTCCTTGTCTTTAGGGGAAATTCCCT
TTTCATATTGTGTGCTTCCCAAAGCTATAGTCATAGATTTCTTCCAGAAACTATTGTCATAATTGTCACTGGAGTGCTTAAATATACGTACTATACTGAC
AAAATACATGGAAGTGAGTTATAATGAGGCAGAAACAAAATCCTCGGTAACATTGATGATACTCTACCGATCACCGTGGTTTTGGAAAGTCAGTCAACAG
TTGTATTATTGCACTCAATTTCATTGTGACATTTTATTTAACTTCTTCATCTTGGTGGTCCTTGCCCAGTTATTTTGCCTCATTAGACATCAAGAAATGG
AGAAAGACTGAAAGTTAATATCTTAAGTGCTTGTTCTTCATGTTTCCTTCTTGTTATTTATGCTATTCTCTTTGTGGCTCCATTCTTCTTTCAATCTTCT
CAGCTTATAACCGTCTTTCCCTTATGCTAAGGATAGCCCTTACACTCATCCCATCTATGCTGTCAAGGGCTGCTGGTTGGTGCTGGTACAAGGAGCCCAC
TCAGCAGTTTTCTTACCTTTGCCTGCCCTGCCTTTCATGGAATAAGAAAGGCAACGTTTTGCAGCTTCCAAATTTCTGAAGAAACTAATCTCAGATTGGC
AGTTAAAGTCAAAATGTTGCCAAATATTTATTCCTTTTGCCTAAGTTTGGCTACCCGGTTCAATTGCTTTTTATTTTTAATGTCTTGACTCTTCAGAGTT
CGTACCTCAAAAGAACAATGAGAACATTTGCTTTGCTTTCTGCTGAATCCCTAATCTCAACAATCTATACCTGGACTGTCCAGTTCTCCTCCTGTGCTAT
CTTCTCTTCTATCCAAGTAGAATGTACGCCAGGAGCTCCTTCCCTCTAGCAATTTCTACTAAAATGTCCAAGTAGAATGTTTCCTTTTACAATCAAATTA
CTGTATTTATTAATTTGCTAGAATCCAGTAAATCATTTTGGTAGCTCTGGCTGTGCTATCAATAAAAAGATGAAAGCAACAAGTTGA
  • refseq_AP3M1.F1 (forward primer)
  • refseq_AP3M1.R1 (reverse primer)
  • Single exon skipping

Frame 0

PESRWRETHHFSRPWIM*KI*ILSLKRRLSSHL
RSSC
IFKISNTVDRVGVFEAVNQAISWALQLRVL
AAFSASPASVGEDPAPNH*LAQVLGK*STVYFS
*TVPVTYF*RSTGRAL*ASLSVIISLKLKRKLL
MLKMYHLSFQHLTTTSSVSTGISSSLYLSYRPKC
HLSL*LSSYIELLTLFRTTLVSVQRLQLRIMWS
*YMNS*KKC*TMDFHWLPNLTF*KN*LNHQQFY
ALLSTLLQAVVMLGTHSPPGSCPTYHGVGQG*ST
QTMKPILMLLKK*TQL*INQDLQSLQKFRGSLM
LALNYLECLISPFLS*TLGFWMMSAFTPASGSS
VGNLKEFCHLFLQMEISDSYHTVSAHKI*WQYQC
M*NIVSALRRTVLAADLI*QLDQSRIWGKLLKE
LQ*QFTCQKLC*T*T*HPHKAAIHLIQSPRY*H
GMWEKLLHKSSQVLKDW*IYSLEPPNQKRIRAST
YSLRSSSLLFQA*K*TVWTCMGRNISHLKESNT
SRKLESSK*GHEKRPKFLRTSLFSKCHYDVSLL
GTK*VGIHILVKAFVSSYTPLTKLLSYQCRILKE
L*AKETF**LSLFCIFSLRKILEVIFFHRRIPS
GGCTL*Q*RQKAVVITSLLKELTGLIQQKLS*I
CDVSGAAKYHTF*S*PSQTSICPERKFPPPPEVY
RKLPLQVFALFSFSLVPLSKHCSKSHFHMALAG
STAAPCSILTVLGIVFFINKIFM*SLEFDLQGP
CCSKYHLNFVPLVQLLAQ*KNHLYQRGKCFIKVV
KGNITSAFRKLLQAQAFVLLSKLK**KKNLSET
FAIFMFYNIKLTQHQLSHG*PKCLMPQFSKRRK
MCLPHSHQSF*IFFVVVLKGLNLSAFLVFRGNSL
FILCASQSYSHRFLPETIVIIVTGVLKYTYYTD
KIHGSEL**GRNKILGNIDDTLPITVVLESQST
VVLLHSISL*HFI*LLHLGGPCPVILPH*TSRNG
ERLKVNILSACSSCFLLVIYAILFVAPFFFQSS
QLITVFPLC*G*PLHSSHLCCQGLLVGAGTRSP
LSSFLTFACPAFHGIRKATFCSFQISEETNLRLA
VKVKMLPNIYSFCLSLATRFNCFLFLMS*LFRV
RTSKEQ*EHLLCFLLNP*SQQSIPGLSSSPPVL
SSLLSK*NVRQELLPSSNFY*NVQVECFLLQSNY
CIY*FARIQ*IILVALAVLSIKR*KQQV

Frame 1

LNLDGEKPTIFLGPGLCRRFRY*ASRDVFPLIY
GLPA
YLKFLIR*TESVSLKLLIRQFPGHSSCGS
SRPSRLLQLR*ERIRRRITDWHRCWENDPQSISH
KLFR*HISREALEERCEPVCL*LFL*SSRESC*
C*KCTTCHFNTSPLPHQYLPG*ALLCICHTDRS
ATSLCN*VPTSSC*HFSGLLW*VFRGCN*G*CGH
SI*TLRRNVRQWISTGYRI*HFERID*TTNNST
LCCQLYYRQ**CWGHTPHRAAVQHTMASGRGKV
HKQ*SLF*CC*RNRRNYR*IRIYSLCRNSGGH*C
LH*TIWNA*SLPFFHEP*ASG*CQLSPLHPVQA
LGI*KSFVIYSSRWKFPTHIIPCQLTKSSGNTS
VCET*YQL*GEQFLRQI*YNNWTKAEYGENY*RN
YSDSSHAKSCAEHEPDTHTRQLYI*SSHQGTNM
GCGKNYSTKAPKS*RTGKFTVWSPQTRRESEPQ
HTV*DPAACYFRLKSKPFGHVWGEI*AI*RSQIR
HESWKVPSEDMRRGQNSSGPVCFPSVITMYHY*
VPSEWEYIF*LKHLCLATHR*QSYLVINVGFLR
SFKLRKPFSDLAYFVSFHLGRFWR*FFSIGGYHL
AAAHCNSKGRKL***PLS*KS*LVSSSRSYLKS
VMCQVQPNITPSDLSHPKPVSVPRGNSPHPQKF
TENCLFKCLPYSAFHLCH*ASTVAKATSTWPWQG
ALLLHAPFSLYLVLYFL*IRFLCKA*NLIYRDL
AAVNTISILCHWFSC*HSKKIICIKGANALLR*
*KGTLLLLLGSYCKHKHLCF*AN*SSKRKT*VKP
LPSSCFII*SLPNTS*AMVNLNASCPSSAKGGK
CACLTVISLFKSFLLLFLRV*ICLHSLSLGEIP
FSYCVLPKAIVIDFFQKLLS*LSLECLNIRTILT
KYMEVSYNEAETKSSVTLMILYRSPWFWKVSQQ
LYYCTQFHCDILFNFFILVVLAQLFCLIRHQEM
EKD*KLIS*VLVLHVSFLLFMLFSLWLHSSFNLL
SL*PSFPYAKDSPYTHPIYAVKGCWLVLVQGAH
SAVFLPLPALPFME*ERQRFAASKFLKKLISDW
QLKSKCCQIFIPFA*VWLPGSIAFYF*CLDSSEF
VPQKNNENICFAFC*IPNLNNLYLDCPVLLLCY
LLFYPSRMYARSSFPLAISTKMSK*NVSFYNQI
TVFINLLESSKSFW*LWLCYQ*KDESNKL

Frame 2

*I*MERNPPFF*ALDYVEDLDTKPQETSFLSFT
VFL
HI*NF*YGRQSRCL*SC*SGNFLGTPAAGP
RGLLGFSSFGRRGSGAESLTGTGVGKMIHSLFL
INCSGDIFLEKHWKSVVSQSVCDYFFEAQEKAAD
VENVPPVISTPHHYLISIYRDKLFFVSVIQTEV
PPLFVIEFLHRVADTFQDYFGECSEAAIKDNVV
IVYELLEEMLDNGFPLATESNILKELIKPPTILR
SVVNSITGSSNVGDTLPTGQLSNIPWRRAGVKY
TNNEAYFDVVEEIDAIIDKSGSTVFAEIQGVID
ACIKLSGMPDLSLSFMNPRLLDDVSFHPCIRFKR
WESERVLSFIPPDGNFRLISYRVSSQNLVAIPV
YVKHSISFKENSSCGRFDITIGPKQNMGKTIEG
ITVTVHMPKVVLNMNLTPTQGSYTFDPVTKVLTW
DVGKITPQKLPSLKGLVNLQSGAPKPEENPSLN
IQFKIQQLAISGLKVNRLDMYGEKYKPFKGVKY
VTKAGKFQVRT*EEAKIPQDQFVFQVSLRCITIR
YQVSGNTYSS*SICV*LHTANKVT*LSM*DS*G
ALS*GNLLVT*LILYLFT*EDFGGDFFP*EDTI
WRLHIVTVKAESCSDNLSPKRVNWSHPAEAILNL
*CVRCSQISHLLILAIPNQYLSREEIPPTPRSL
QKTASSSVCLIQLFTCAIKQAL*QKPLPHGPGR
EHCCSMLHSHCTWYCIFYK*DFYVKLRI*FTGTL
LQ*IPSQFCATGSAVSTVKKSFVSKGQMLY*GS
KREHYFCF*EVTASTSICAFKQIKVVKEKLK*N
LCHLHVL*YKAYPTPVKPWLT*MPHAPVQQKEEN
VPASQSSVFLNLFCCCS*GFEFVCIPCL*GKFP
FHIVCFPKL*S*ISSRNYCHNCHWSA*IYVLY*
QNTWK*VIMRQKQNPR*H**YSTDHRGFGKSVNS
CIIALNFIVTFYLTSSSWWSLPSYFASLDIKKW
RKTES*YLKCLFFMFPSCYLCYSLCGSILLSIF
SAYNRLSLMLRIALTLIPSMLSRAAGWCWYKEPT
QQFSYLCLPCLSWNKKGNVLQLPNF*RN*SQIG
S*SQNVAKYLFLLPKFGYPVQLLFIFNVLTLQS
SYLKRTMRTFALLSAESLISTIYTWTVQFSSCAI
FSSIQVECTPGAPSL*QFLLKCPSRMFPFTIKL
LYLLIC*NPVNHFGSSGCAINKKMKATS*

Sequence NM_207012

CCTGAATCTAGATGGAGAGAAACCCACCATTTTTCTAGGCCCTGGATTATGTAGAAGATTTAGATACTAAGCCTCAAGAGACGTCTTTCCTCTCATTTAC
GGTCTTCCTGC
ATATTTAAAATTTCTAATACGGTAGACAGAGTCGGTGTCTTTGAAGCTGTTAATCAGGCAATTTCCTGGGCACTCCAGCTGCGGGTCCT
CGCGGCCTTCTCGGCTTCTCCAGCTTCGGTAGGAGAGGATCCGGCGCCGAATCACTGACTGGCACAGGTGTTGGGATAGTGTCTCACTTGGTCACCCAGG
CTGGAGTGCAGTGGCGCAATCTTAGCTCTCTACAGCGTCGATCTTCCTCCTGGGCTCAAGCAATTCTCCTGCTTCATCCTCCTGAGTACCTAGGACTACA
G
AAAATGATCCACAGTCTATTTCTCATAAACTGTTCCGGTGACATATTTCTAGAGAAGCACTGGAAGAGCGTTGTGAGCCAGTCTGTCTGTGATTATTTC
TTTGAAGCTCAAGAGAAAGCTGCTGATGTTGAAAATGTACCACCTGTCATTTCAACACCTCACCACTACCTCATCAGTATCTACCGGGATAAGCTCTTCT
TTGTATCTGTCATACAGACCGAAGTGCCACCTCTCTTTGTAATTGAGTTCCTACATCGAGTTGCTGACACTTTTCAGGACTACTTTGGTGAGTGTTCAGA
GGCTGCAATTAAGGATAATGTGGTCATAGTATATGAACTCTTAGAAGAAATGTTAGACAATGGATTTCCACTGGCTACCGAATCTAACATTTTGAAAGAA
TTGATTAAACCACCAACAATTCTACGCTCTGTTGTCAACTCTATTACAGGCAGTAGTAATGTTGGGGACACACTCCCCACCGGGCAGCTGTCCAACATAC
CATGGCGTCGGGCAGGGGTAAAGTACACAAACAATGAAGCCTATTTTGATGTTGTTGAAGAAATAGACGCAATTATAGATAAATCAGGATCTACAGTCTT
TGCAGAAATTCAGGGGGTCATTGATGCTTGCATTAAACTATCTGGAATGCCTGATCTCTCCCTTTCTTTCATGAACCCTAGGCTTCTGGATGATGTCAGC
TTTCACCCCTGCATCCGGTTCAAGCGTTGGGAATCTGAAAGAGTTTTGTCATTTATTCCTCCAGATGGAAATTTCCGACTCATATCATACCGTGTCAGCT
CACAAAATCTAGTGGCAATACCAGTGTATGTGAAACATAGTATCAGCTTTAAGGAGAACAGTTCTTGCGGCAGATTTGATATAACAATTGGACCAAAGCA
GAATATGGGGAAAACTATTGAAGGAATTACAGTGACAGTTCACATGCCAAAAGTTGTGCTGAACATGAACCTGACACCCACACAAGGCAGCTATACATTT
GATCCAGTCACCAAGGTACTAACATGGGATGTGGGAAAAATTACTCCACAAAAGCTCCCAAGTCTTAAAGGACTGGTAAATTTACAGTCTGGAGCCCCCA
AACCAGAAGAGAATCCGAGCCTCAACATACAGTTTAAGATCCAGCAGCTTGCTATTTCAGGCTTAAAAGTAAACCGTTTGGACATGTATGGGGAGAAATA
TAAGCCATTTAAAGGAGTCAAATACGTCACGAAAGCTGGAAAGTTCCAAGTGAGGACATGAGAAGAGGCCAAAATTCCTCAGGACCAGTTTGTTTTCCAA
GTGTCATTACGATGTATCACTATTAGGTACCAAGTGAGTGGGAATACATATTCTAGTTAAAGCATTTGTGTCTAGCTACACACCGCTAACAAAGTTACTT
AGTTATCAATGTAGGATTCTTAAGGAGCTTTAAGCTAAGGAAACCTTTTAGTGACTTAGCTTATTTTGTATCTTTTCACTTAGGAAGATTTTGGAGGTGA
TTTTTTTCCATAGGAGGATACCATCTGGCGGCTGCACATTGTAACAGTAAAGGCAGAAAGCTGTAGTGATAACCTCTCTCCTAAAAGAGTTAACTGGTCT
CATCCAGCAGAAGCTATCTTAAATCTGTGATGTGTCAGGTGCAGCCAAATATCACACCTTCTGATCTTAGCCATCCCAAACCAGTATCTGTCCCGAGAGG
AAATTCCCCCCACCCCCAGAAGTTTACAGAAAACTGCCTCTTCAAGTGTTTGCCTTATTCAGCTTTTCACTTGTGCCATTAAGCAAGCACTGTAGCAAAA
GCCACTTCCACATGGCCCTGGCAGGGAGCACTGCTGCTCCATGCTCCATTCTCACTGTACTTGGTATTGTATTTTTTATAAATAAGATTTTTATGTAAAG
CTTAGAATTTGATTTACAGGGACCTTGCTGCAGTAAATACCATCTCAATTTTGTGCCACTGGTTCAGCTGTTAGCACAGTAAAAAAATCATTTGTATCAA
AGGGGCAAATGCTTTATTAAGGTAGTAAAAGGGAACATTACTTCTGCTTTTAGGAAGTTACTGCAAGCACAAGCATTTGTGCTTTTAAGCAAATTAAAGT
AGTAAAAGAAAAACTTAAGTGAAACCTTTGCCATCTTCATGTTTTATAATATAAAGCTTACCCAACACCAGTTAAGCCATGGTTAACCTAAATGCCTCAT
GCCCCAGTTCAGCAAAAGGAGGAAAATGTGCCTGCCTCACAGTCATCAGTCTTTTTAAATCTTTTTTGTTGTTGTTCTTAAGGGTTTGAATTTGTCTGCA
TTCCTTGTCTTTAGGGGAAATTCCCTTTTCATATTGTGTGCTTCCCAAAGCTATAGTCATAGATTTCTTCCAGAAACTATTGTCATAATTGTCACTGGAG
TGCTTAAATATACGTACTATACTGACAAAATACATGGAAGTGAGTTATAATGAGGCAGAAACAAAATCCTCGGTAACATTGATGATACTCTACCGATCAC
CGTGGTTTTGGAAAGTCAGTCAACAGTTGTATTATTGCACTCAATTTCATTGTGACATTTTATTTAACTTCTTCATCTTGGTGGTCCTTGCCCAGTTATT
TTGCCTCATTAGACATCAAGAAATGGAGAAAGACTGAAAGTTAATATCTTAAGTGCTTGTTCTTCATGTTTCCTTCTTGTTATTTATGCTATTCTCTTTG
TGGCTCCATTCTTCTTTCAATCTTCTCAGCTTATAACCGTCTTTCCCTTATGCTAAGGATAGCCCTTACACTCATCCCATCTATGCTGTCAAGGGCTGCT
GGTTGGTGCTGGTACAAGGAGCCCACTCAGCAGTTTTCTTACCTTTGCCTGCCCTGCCTTTCATGGAATAAGAAAGGCAACGTTTTGCAGCTTCCAAATT
TCTGAAGAAACTAATCTCAGATTGGCAGTTAAAGTCAAAATGTTGCCAAATATTTATTCCTTTTGCCTAAGTTTGGCTACCCGGTTCAATTGCTTTTTAT
TTTTAATGTCTTGACTCTTCAGAGTTCGTACCTCAAAAGAACAATGAGAACATTTGCTTTGCTTTCTGCTGAATCCCTAATCTCAACAATCTATACCTGG
ACTGTCCAGTTCTCCTCCTGTGCTATCTTCTCTTCTATCCAAGTAGAATGTACGCCAGGAGCTCCTTCCCTCTAGCAATTTCTACTAAAATGTCCAAGTA
GAATGTTTCCTTTTACAATCAAATTACTGTATTTATTAATTTGCTAGAATCCAGTAAATCATTTTGGTAGCTCTGGCTGTGCTATCAATAAAAAGATGAA
AGCAACAAGTTGA
  • refseq_AP3M1.F1 (forward primer)
  • refseq_AP3M1.R1 (reverse primer)
  • Single exon skipping

Frame 0

PESRWRETHHFSRPWIM*KI*ILSLKRRLSSHL
RSSC
IFKISNTVDRVGVFEAVNQAISWALQLRVL
AAFSASPASVGEDPAPNH*LAQVLG*CLTWSPR
LECSGAILALYSVDLPPGLKQFSCFILLST*DY
R
K*STVYFS*TVPVTYF*RSTGRAL*ASLSVIIS
LKLKRKLLMLKMYHLSFQHLTTTSSVSTGISSS
LYLSYRPKCHLSL*LSSYIELLTLFRTTLVSVQ
RLQLRIMWS*YMNS*KKC*TMDFHWLPNLTF*KN
*LNHQQFYALLSTLLQAVVMLGTHSPPGSCPTY
HGVGQG*STQTMKPILMLLKK*TQL*INQDLQS
LQKFRGSLMLALNYLECLISPFLS*TLGFWMMSA
FTPASGSSVGNLKEFCHLFLQMEISDSYHTVSA
HKI*WQYQCM*NIVSALRRTVLAADLI*QLDQS
RIWGKLLKELQ*QFTCQKLC*T*T*HPHKAAIHL
IQSPRY*HGMWEKLLHKSSQVLKDW*IYSLEPP
NQKRIRASTYSLRSSSLLFQA*K*TVWTCMGRN
ISHLKESNTSRKLESSK*GHEKRPKFLRTSLFSK
CHYDVSLLGTK*VGIHILVKAFVSSYTPLTKLL
SYQCRILKEL*AKETF**LSLFCIFSLRKILEV
IFFHRRIPSGGCTL*Q*RQKAVVITSLLKELTGL
IQQKLS*ICDVSGAAKYHTF*S*PSQTSICPER
KFPPPPEVYRKLPLQVFALFSFSLVPLSKHCSK
SHFHMALAGSTAAPCSILTVLGIVFFINKIFM*S
LEFDLQGPCCSKYHLNFVPLVQLLAQ*KNHLYQ
RGKCFIKVVKGNITSAFRKLLQAQAFVLLSKLK
**KKNLSETFAIFMFYNIKLTQHQLSHG*PKCLM
PQFSKRRKMCLPHSHQSF*IFFVVVLKGLNLSA
FLVFRGNSLFILCASQSYSHRFLPETIVIIVTG
VLKYTYYTDKIHGSEL**GRNKILGNIDDTLPIT
VVLESQSTVVLLHSISL*HFI*LLHLGGPCPVI
LPH*TSRNGERLKVNILSACSSCFLLVIYAILF
VAPFFFQSSQLITVFPLC*G*PLHSSHLCCQGLL
VGAGTRSPLSSFLTFACPAFHGIRKATFCSFQI
SEETNLRLAVKVKMLPNIYSFCLSLATRFNCFL
FLMS*LFRVRTSKEQ*EHLLCFLLNP*SQQSIPG
LSSSPPVLSSLLSK*NVRQELLPSSNFY*NVQV
ECFLLQSNYCIY*FARIQ*IILVALAVLSIKR*
KQQV

Frame 1

LNLDGEKPTIFLGPGLCRRFRY*ASRDVFPLIY
GLPA
YLKFLIR*TESVSLKLLIRQFPGHSSCGS
SRPSRLLQLR*ERIRRRITDWHRCWDSVSLGHPG
WSAVAQS*LSTASIFLLGSSNSPASSS*VPRTT
ENDPQSISHKLFR*HISREALEERCEPVCL*LF
L*SSRESC*C*KCTTCHFNTSPLPHQYLPG*ALL
CICHTDRSATSLCN*VPTSSC*HFSGLLW*VFR
GCN*G*CGHSI*TLRRNVRQWISTGYRI*HFER
ID*TTNNSTLCCQLYYRQ**CWGHTPHRAAVQHT
MASGRGKVHKQ*SLF*CC*RNRRNYR*IRIYSL
CRNSGGH*CLH*TIWNA*SLPFFHEP*ASG*CQ
LSPLHPVQALGI*KSFVIYSSRWKFPTHIIPCQL
TKSSGNTSVCET*YQL*GEQFLRQI*YNNWTKA
EYGENY*RNYSDSSHAKSCAEHEPDTHTRQLYI
*SSHQGTNMGCGKNYSTKAPKS*RTGKFTVWSPQ
TRRESEPQHTV*DPAACYFRLKSKPFGHVWGEI
*AI*RSQIRHESWKVPSEDMRRGQNSSGPVCFP
SVITMYHY*VPSEWEYIF*LKHLCLATHR*QSYL
VINVGFLRSFKLRKPFSDLAYFVSFHLGRFWR*
FFSIGGYHLAAAHCNSKGRKL***PLS*KS*LV
SSSRSYLKSVMCQVQPNITPSDLSHPKPVSVPRG
NSPHPQKFTENCLFKCLPYSAFHLCH*ASTVAK
ATSTWPWQGALLLHAPFSLYLVLYFL*IRFLCK
A*NLIYRDLAAVNTISILCHWFSC*HSKKIICIK
GANALLR**KGTLLLLLGSYCKHKHLCF*AN*S
SKRKT*VKPLPSSCFII*SLPNTS*AMVNLNAS
CPSSAKGGKCACLTVISLFKSFLLLFLRV*ICLH
SLSLGEIPFSYCVLPKAIVIDFFQKLLS*LSLE
CLNIRTILTKYMEVSYNEAETKSSVTLMILYRS
PWFWKVSQQLYYCTQFHCDILFNFFILVVLAQLF
CLIRHQEMEKD*KLIS*VLVLHVSFLLFMLFSL
WLHSSFNLLSL*PSFPYAKDSPYTHPIYAVKGC
WLVLVQGAHSAVFLPLPALPFME*ERQRFAASKF
LKKLISDWQLKSKCCQIFIPFA*VWLPGSIAFY
F*CLDSSEFVPQKNNENICFAFC*IPNLNNLYL
DCPVLLLCYLLFYPSRMYARSSFPLAISTKMSK*
NVSFYNQITVFINLLESSKSFW*LWLCYQ*KDE
SNKL

Frame 2

*I*MERNPPFF*ALDYVEDLDTKPQETSFLSFT
VFL
HI*NF*YGRQSRCL*SC*SGNFLGTPAAGP
RGLLGFSSFGRRGSGAESLTGTGVGIVSHLVTQ
AGVQWRNLSSLQRRSSSWAQAILLLHPPEYLGLQ
KMIHSLFLINCSGDIFLEKHWKSVVSQSVCDYF
FEAQEKAADVENVPPVISTPHHYLISIYRDKLF
FVSVIQTEVPPLFVIEFLHRVADTFQDYFGECSE
AAIKDNVVIVYELLEEMLDNGFPLATESNILKE
LIKPPTILRSVVNSITGSSNVGDTLPTGQLSNI
PWRRAGVKYTNNEAYFDVVEEIDAIIDKSGSTVF
AEIQGVIDACIKLSGMPDLSLSFMNPRLLDDVS
FHPCIRFKRWESERVLSFIPPDGNFRLISYRVS
SQNLVAIPVYVKHSISFKENSSCGRFDITIGPKQ
NMGKTIEGITVTVHMPKVVLNMNLTPTQGSYTF
DPVTKVLTWDVGKITPQKLPSLKGLVNLQSGAP
KPEENPSLNIQFKIQQLAISGLKVNRLDMYGEKY
KPFKGVKYVTKAGKFQVRT*EEAKIPQDQFVFQ
VSLRCITIRYQVSGNTYSS*SICV*LHTANKVT
*LSM*DS*GALS*GNLLVT*LILYLFT*EDFGGD
FFP*EDTIWRLHIVTVKAESCSDNLSPKRVNWS
HPAEAILNL*CVRCSQISHLLILAIPNQYLSRE
EIPPTPRSLQKTASSSVCLIQLFTCAIKQAL*QK
PLPHGPGREHCCSMLHSHCTWYCIFYK*DFYVK
LRI*FTGTLLQ*IPSQFCATGSAVSTVKKSFVS
KGQMLY*GSKREHYFCF*EVTASTSICAFKQIKV
VKEKLK*NLCHLHVL*YKAYPTPVKPWLT*MPH
APVQQKEENVPASQSSVFLNLFCCCS*GFEFVC
IPCL*GKFPFHIVCFPKL*S*ISSRNYCHNCHWS
A*IYVLY*QNTWK*VIMRQKQNPR*H**YSTDH
RGFGKSVNSCIIALNFIVTFYLTSSSWWSLPSY
FASLDIKKWRKTES*YLKCLFFMFPSCYLCYSLC
GSILLSIFSAYNRLSLMLRIALTLIPSMLSRAA
GWCWYKEPTQQFSYLCLPCLSWNKKGNVLQLPN
F*RN*SQIGS*SQNVAKYLFLLPKFGYPVQLLFI
FNVLTLQSSYLKRTMRTFALLSAESLISTIYTW
TVQFSSCAIFSSIQVECTPGAPSL*QFLLKCPS
RMFPFTIKLLYLLIC*NPVNHFGSSGCAINKKMK
ATS*

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