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Sequences

Sequence NM_001009569

ATGGTCTCTAGCGACCGGCCCGTGTCACTGGAGGACGAGGTCTCCCATAGTATGAAGGAGATGATTGGAGGCTGTTGCGTTTGCTCAGACGAGAGAGGCT
GGGCCGAGAACCCGCTGGTTTATTGCGACGGGCACGGCTGCAGCGTCGCGGTGCATCAAGCTTGCTATGGCATTGTTCAAGTACCCACTGGACCGTGGTT
TTGCAGGAAATGTGAATCTCAGGAGAGAGCAGCCAGAGTGAGATGTGAACTTTGTCCCCATAAGGATGGAGCTTTAAAAAGAACAGATAATGGGGGTTGG
GCCCATGTGGTTTGTGCCCTGTATATTCCAGAGGTACAATTTGCCAATGTTTCCACAATGGAACCAATTGTTTTACAGTCTGTTCCGCATGATCGTTATA
ATAAGACTTGCTACATTTGTGATGAACAAGGAAGAGAAAGCAAAGCAGCCACTGGTGCTTGCATGACATGTAATAAACATGGATGTCGACAGGCTTTCCA
TGTAACATGCGCTCAGTTTGCCGGACTGCTTTGTGAAGAAGAAGGTAATGGTGCCGATAATGTCCAATACTGTGGCTACTGTAAATACCATTTTAGTAAG
CTGAAAAAGAGCAAACGGGGATCTAATAGGTCATATGATCAAAGTTTAAGTGATTCTTCCTCTCACTCTCAGGATAAACATCATGAGAAAGAGAAAAAAA
AATATAAAGAGAAGGACAAACACAAACAGAAACACAAGAAGCAGCCAGAACCATCACCTGCATTGGTTCCATCCTTGACTGTTACTACAGAAAAAACTTA
TACAAGCACTAGCAACAACTCTATATCTGGATCATTGAAGCGCTTGGAAGATACTACTGCACGATTTACAAATGCAAATTTCCAGGAAGTCTCTGCACAC
ACCTCTAGTGGAAAAGATGTTTCAGAGACTAGAGGGTCAGAGGGCAAAGGGAAGAAATCTTCAGCTCACAGCTCAGGTCAAAGGGGAAGAAAGCCTGGTG
GTGGAAGAAATCCAGGAACAACTGTGTCAGCAGCTAGCCCTTTTCCTCAAGGCAGTTTTTCAGGAACTCCAGGCAGTGTAAAGTCATCTTCTGGAAGTTC
AGTGCAGTCTCCCCAGGATTTCCTGAGCTTTACAGACTCAGATCTGCGTAATGACAGTTACTCTCACTCCCAACAGTCATCAGCAACCAAAGATGTACAT
AAAGGAGAGTCTGGAAGCCAGGAAGGGGGGGTAAATAGTTTTAGTACCTTAATTGGCCTCCCTTCAACCTCAGCTGTTACTTCACAGCCTAAAAGCTTTG
AAAATTCACCTGGAGATTTGGGTAATTCCAGCCTTCCTACAGCAGGATATAAGCGGGCTCAAACTTCTGGCATAGAAGAAGAAACTGTAAAGGAAAAGAA
AAGGAAAGGAAATAAACAAAGTAAGCATGGGCCTGGCAGACCCAAAGGAAACAAAAATCAAGAGAATGTTTCTCATCTCTCAGTTTCTTCTGCTTCACCA
ACATCATCTGTAGCATCAGCTGCAGGAAGCATAACAAGCTCTAGTCTGCAGAAATCTCCTACATTGCTCAGGAATGGAAGTTTACAGAGCCTCAGTGTTG
GCTCATCTCCAGTTGGTTCAGAAATTTCCATGCAGTATCGGCATGATGGAGCTTGCCCAACAACTACGTTCTCAGAGTTGCTGAATGCAATACACAACGG
TATTTATAACAGCAATGATGTAGCAGTATCGTTTCCAAATGTAGTATCTGGCTCGGGATCTAGTACTCCTGTCTCCAGCTCTCACTTACCTCAGCAGTCT
TCTGGGCATTTGCAACAAGTAGGAGCGCTCTCTCCCTCAGCTGTGTCATCTGCAGCCCCTGCTGTTGCTACAACTCAGGCAAATACTCTATCTGGATCTT
CTCTCAGTCAGGCACCATCTCATATGTATGGCAATAGATCAAATTCATCAATGGCAGCTCTTATAGCTCAGTCTGAAAACAATCAAACAGATCAAGATCT
TGGAGACAATAGCCGCAACCTAGTTGGCAGAGGAAGCTCACCCCGAGGAAGTCTCTCGCCACGATCCCCTGTAAGCAGCTTACAGATTCGCTATGATCAA
CCAGGCAACAGCAGTTTGGAAAATCTGCCTCCAGTAGCAGCCAGCATAGAACAGCTTTTGGAGAGGCAGTGGAGTGAAGGACAGCAATTTTTACTAGAAC
AGGGTACTCCTAGTGACATTTTAGGAATGCTGAAGTCATTACACCAACTTCAAGTTGAAAACCGAAGATTAGAGGAACAAATTAAAAACTTGACTGCCAA
AAAGGAACGGCTTCAGTTATTGAATGCACAGCTTTCAGTGCCTTTTCCAACAATAACAGCAAATCCTAGTCCGTCTCATCAAATACACACATTTTCAGCA
CAGACTGCTCCTACTACTGATTCCTTGAACAGCAGTAAGAGCCCTCATATAGGAAACAGCTTTTTACCTGATAATTCTCTTCCTGTATTAAATCAGGACT
TAACCTCCAGTGGACAAAGTACCAGCAGCTCATCAGCTCTTTCTACCCCACCTCCTGCTGGGCAGAGTCCGGCTCAACAAGGCTCAGGAGTGAGTGGAGT
TCAGCAGGTCAATGGCGTGACAGTGGGGGCACTAGCTAGTGGAATGCAGCCTGTAACTTCCACCATTCCTGCCGTGTCTGCAGTGGGTGGAATAATTGGA
GCTTTGCCAGGTAACCAACTGGCAATTAATGGCATTGTAGGAGCTTTAAATGGGGTTATGCAGACTCCTGTCACAATGTCCCAGAACCCTACCCCTCTCA
CCCACACAACCGTACCACCTAATGCAACACATCCAATGCCAGCTACACTGACTAACAGTGCCTCAGGACTAGGATTACTTTCTGACCAGCAACGACAAAT
ACTTATTCATCAACAGCAGTTTCAGCAGTTGTTAAATTCTCAACAGCTCACACCAGTACACAGGCACCCCCACTTCACACAGCTACCACCAACCCATTTC
TCACCATCCATGGAGATAATGCAAGTCAGAAAGTAGCAAGACTTAGTGATAAAACTGGGCCTGTAGCTCAAGAGAAAAGTTGACACCTGAGAAACATCTA
GAAATTGCCTATCCTGCTGTTCTAGCACTTCATCTGGCTGCCTTTGCAGTCCTTTTACTACAGCTATGAAGAAACGCAACAAGAAACTCAATGCACAACA
AAGGATTAATTGCTGCAAGGACATTCTTGTAAGGCTTTGATTAGTTTTCTTGTTGCTTTGTTGCACTGAAATGGAATTCCCATGCCCCTACCCCTTACCC
CAGTTTTTTGAACATGGAAAGAAAATTTAATAACTTTTTAAAGTGACATAATTTACATGCAATATGTTTATCAACTCAAGAATTTAATATAGTTGGTACA
CAACTAGTTTTGTTTATAAATTGGAGATGCAAATAGCAAAACTAAATACTTGCTCCATTTACAAACTACTTGATTTTATTGTACAAGTTGAAATATGCTC
TTTTGTTTGGGTTACAGTATGCTTGCTCTAAGTCAAATTCCAAGGAACTAATTTCTTCTCCTGGAGTTGCATTGATTCAGTATTACAAATATATAGCACA
TCACCTGGGACTTGGCAATCTTTGTTAAAAAAAAATTTCCTTTCTAATGGGATTTGGCCAATTTTGGTAATGAAGTTAGGATGGTAATGTCTGCATCTGC
TAAAGGTAATTTTCTTTTGAGAATTGCTTTCTTTAGTGTTAAGACCTACTCATATTTTGAAGAAATCTTGAGTTAAGTGAGTTCTGAGGCTGCTGGGGGA
ACCAGATCAATTCAAAGCTAAATACTTCTTTCAGAAAGGGGCCACTGTGGAAAGTGCTGGTGGGGTTTGCCCTTGATCAAGTGCCTCCATTGTGCTGCAA
GGGCTGTAGACAGCAGGGTGGGACAGTCAGTCCTCCGAGCAGCAGGAATCATCCCGTCACCTGCAGCCTTCCCATGCTTCCGCCTTTATTCAGAACTTTC
TGTGCCACTGTAGATAGCTCAGGCAAAACTATTACCTGGGTATTTATCCACTAATGAGTCACAAGAAAAGGAGTGGATTTGGTAAGAATAGAGATTTGTT
TTATTTAAACCACTTCCCATTACTGACCATTAAAAGCTCACCACTAGAGTTCCTGAAACAGGTGAAACCTGTATGACAGCCCTTCCACTTTGGGGAGCCA
CGCTTTTGATGTGACAGTACCGCAGAGTGATTCCCCCACTGAGGATGTCATCATCAAACTCTTCTTTGGTGTGTGAATTATTAGTGGAAAAGACCCAGCT
GTAATTAGACCTCCACTGTGTACTTAGCTGGAAGAACATGTTAATTCTGCAATATGTTTCTTGGTTAAACATTGCACAGTTCTTACCTCATTTCTGTAAA
TAAAGTTTTGTGAATCTGTTTTGTATTGTGACAAATTCATAAGATAACATTGATATTTTGATTTGTAATATTTCTAATTGGTAGATTTAATTGAAAAGTA
AAATTAATTTATTTTTATATGTTCAGGGGAATTTTAAAGTCAAATCTTTTGTAGATAATTTAAAAAATCAGTGTGGTTTATTTTACTTATTTAACCCACT
GGTTGTTATTCTGTAACAGTTTGTATAAATGGTAAATTTTGAATGTGTTGTTATTTTACCTAGATGTAAAATTCCACATGTATTAAAATGTACAAAATGT
TTTGTTAATAAAATTTAATAATGTT
  • refseq_MLLT10.F1 (forward primer)
  • refseq_MLLT10.R1 (reverse primer)
  • Single exon skipping

Frame 0

MVSSDRPVSLEDEVSHSMKEMIGGCCVCSDERG
WAENPLVYCDGHGCSVAVHQACYGIVQVPTGPWF
CRKCESQERAARVRCELCPHKDGALKRTDNGGW
AHVVCALYIPEVQFANVSTMEPIVLQSVPHDRY
NKTCYICDEQGRESKAATGACMTCNKHGCRQAFH
VTCAQFAGLLCEEEGNGADNVQYCGYCKYHFSK
LKKSKRGSNRSYDQSLSDSSSHSQDKHHEKEKK
KYKEKDKHKQKHKKQPEPSPALVPSLTVTTEKTY
TSTSNNSISGSLKRLEDTTARFTNANFQEVSAH
TSSGKDVSETRGSEGKGKKSSAHSSGQRGRKPG
GGRNPGTTVSAASPFPQGSFSGTPGSVKSSSGSS
VQSPQDFLSFTDSDLRNDSYSHSQQSSATKDVH
KGESGSQEGGVNSFSTLIGLPSTSAVTSQPKSF
ENSPGDLGNSSLPTAGYKRAQTSGIEEETVKEKK
RKGNKQSKHGPGRPKGNKNQENVSHLSVSSASP
TSSVASAAGSITSSSLQKSPTLLRNGSLQSLSV
GSSPVGSEISMQYRHDGACPTTTFSELLNAIHNG
IYNSNDVAVSFPNVVSGSGSSTPVSSSHLPQQS
SGHLQQVGALSPSAVSSAAPAVATTQANTLSGS
SLSQAPSHMYGNRSNSSMAALIAQSENNQTDQDL
GDNSRNLVGRGSSPRGSLSPRSPVSSLQIRYDQ
PGNSSLENLPPVAASIEQLLERQWSEGQQFLLE
QGTPSDILGMLKSLHQLQVENRRLEEQIKNLTAK
KERLQLLNAQLSVPFPTITANPSPSHQIHTFSA
QTAPTTDSLNSSKSPHIGNSFLPDNSLPVLNQD
LTSSGQSTSSSSALSTPPPAGQSPAQQGSGVSGV
QQVNGVTVGALASGMQPVTSTIPAVSAVGGIIG
ALPGNQLAINGIVGALNGVMQTPVTMSQNPTPL
THTTVPPNATHPMPATLTNSASGLGLLSDQQRQI
LIHQQQFQQLLNSQQLTPVHRHPHFTQLPPTHF
SPSMEIMQVRK*QDLVIKLGL*LKRKVDT*ETS
RNCLSCCSSTSSGCLCSPFTTAMKKRNKKLNAQQ
RINCCKDILVRL*LVFLLLCCTEMEFPCPYPLP
QFFEHGKKI**LFKVT*FTCNMFINSRI*YSWY
TTSFVYKLEMQIAKLNTCSIYKLLDFIVQVEICS
FVWVTVCLL*VKFQGTNFFSWSCIDSVLQIYST
SPGTWQSLLKKNFLSNGIWPILVMKLGW*CLHL
LKVIFF*ELLSLVLRPTHILKKS*VK*VLRLLGE
PDQFKAKYFFQKGATVESAGGVCP*SSASIVLQ
GL*TAGWDSQSSEQQESSRHLQPSHASAFIQNF
LCHCR*LRQNYYLGIYPLMSHKKRSGFGKNRDLF
YLNHFPLLTIKSSPLEFLKQVKPV*QPFHFGEP
RF*CDSTAE*FPH*GCHHQTLLWCVNY*WKRPS
CN*TSTVYLAGRTC*FCNMFLG*TLHSSYLISVN
KVL*ICFVL*QIHKITLIF*FVIFLIGRFN*KV
KLIYFYMFRGILKSNLL*II*KISVVYFTYLTH
WLLFCNSLYKW*ILNVLLFYLDVKFHMY*NVQNV
LLIKFNNV

Frame 1

WSLATGPCHWRTRSPIV*RR*LEAVAFAQTREA
GPRTRWFIATGTAAASRCIKLAMALFKYPLDRG
FAGNVNLRREQPE*DVNFVPIRMEL*KEQIMGVG
PMWFVPCIFQRYNLPMFPQWNQLFYSLFRMIVI
IRLATFVMNKEEKAKQPLVLA*HVINMDVDRLS
M*HALSLPDCFVKKKVMVPIMSNTVATVNTILVS
*KRANGDLIGHMIKV*VILPLTLRINIMRKRKK
NIKRRTNTNRNTRSSQNHHLHWFHP*LLLQKKL
IQALATTLYLDH*SAWKILLHDLQMQISRKSLHT
PLVEKMFQRLEGQRAKGRNLQLTAQVKGEESLV
VEEIQEQLCQQLALFLKAVFQELQAV*SHLLEV
QCSLPRIS*ALQTQICVMTVTLTPNSHQQPKMYI
KESLEARKGG*IVLVP*LASLQPQLLLHSLKAL
KIHLEIWVIPAFLQQDISGLKLLA*KKKL*RKR
KGKEINKVSMGLADPKETKIKRMFLISQFLLLHQ
HHL*HQLQEA*QALVCRNLLHCSGMEVYRASVL
AHLQLVQKFPCSIGMMELAQQLRSQSC*MQYTT
VFITAMM*QYRFQM*YLARDLVLLSPALTYLSSL
LGICNK*ERSLPQLCHLQPLLLLQLRQILYLDL
LSVRHHLICMAIDQIHQWQLL*LSLKTIKQIKI
LETIAAT*LAEEAHPEEVSRHDPL*AAYRFAMIN
QATAVWKICLQ*QPA*NSFWRGSGVKDSNFY*N
RVLLVTF*EC*SHYTNFKLKTED*RNKLKT*LP
KRNGFSY*MHSFQCLFQQ*QQILVRLIKYTHFQH
RLLLLLIP*TAVRALI*ETAFYLIILFLY*IRT
*PPVDKVPAAHQLFLPHLLLGRVRLNKAQE*VE
FSRSMA*QWGH*LVECSL*LPPFLPCLQWVE*LE
LCQVTNWQLMAL*EL*MGLCRLLSQCPRTLPLS
PTQPYHLMQHIQCQLH*LTVPQD*DYFLTSNDK
YLFINSSFSSC*ILNSSHQYTGTPTSHSYHQPIS
HHPWR*CKSESSKT***NWACSSREKLTPEKHL
EIAYPAVLALHLAAFAVLLLQL*RNATRNSMHN
KGLIAARTFL*GFD*FSCCFVALKWNSHAPTPYP
SFLNMERKFNNFLK*HNLHAICLSTQEFNIVGT
QLVLFINWRCK*QN*ILAPFTNYLILLYKLKYA
LLFGLQYACSKSNSKELISSPGVALIQYYKYIAH
HLGLGNLC*KKISFLMGFGQFW**S*DGNVCIC
*R*FSFENCFL*C*DLLIF*RNLELSEF*GCWG
NQINSKLNTSFRKGPLWKVLVGFALDQVPPLCCK
GCRQQGGTVSPPSSRNHPVTCSLPMLPPLFRTF
CATVDSSGKTITWVFIH**VTRKGVDLVRIEIC
FI*TTSHY*PLKAHH*SS*NR*NLYDSPSTLGSH
AFDVTVPQSDSPTEDVIIKLFFGV*IISGKDPA
VIRPPLCT*LEEHVNSAICFLVKHCTVLTSFL*
IKFCESVLYCDKFIR*H*YFDL*YF*LVDLIEK*
N*FIFICSGEF*SQIFCR*FKKSVWFILLI*PT
GCYSVTVCINGKF*MCCYFT*M*NSTCIKMYKM
FC**NLIM

Frame 2

GL*RPARVTGGRGLP*YEGDDWRLLRLLRRERL
GREPAGLLRRARLQRRGASSLLWHCSSTHWTVV
LQEM*ISGESSQSEM*TLSP*GWSFKKNR*WGL
GPCGLCPVYSRGTICQCFHNGTNCFTVCSA*SL*
*DLLHL**TRKRKQSSHWCLHDM**TWMSTGFP
CNMRSVCRTAL*RRR*WCR*CPILWLL*IPF**
AEKEQTGI**VI*SKFK*FFLSLSG*TS*EREKK
I*REGQTQTETQEAARTITCIGSILDCYYRKNL
YKH*QQLYIWIIEALGRYYCTIYKCKFPGSLCT
HL*WKRCFRD*RVRGQREEIFSSQLRSKGKKAWW
WKKSRNNCVSS*PFSSRQFFRNSRQCKVIFWKF
SAVSPGFPELYRLRSA**QLLSLPTVISNQRCT
*RRVWKPGRGGK*F*YLNWPPFNLSCYFTA*KL*
KFTWRFG*FQPSYSRI*AGSNFWHRRRNCKGKE
KERK*TK*AWAWQTQRKQKSRECFSSLSFFCFT
NIICSISCRKHNKL*SAEISYIAQEWKFTEPQCW
LISSWFRNFHAVSA*WSLPNNYVLRVAECNTQR
YL*QQ*CSSIVSKCSIWLGI*YSCLQLSLTSAV
FWAFATSRSALSLSCVICSPCCCYNSGKYSIWIF
SQSGTISYVWQ*IKFINGSSYSSV*KQSNRSRS
WRQ*PQPSWQRKLTPRKSLATIPCKQLTDSL*S
TRQQQFGKSASSSSQHRTAFGEAVE*RTAIFTRT
GYS**HFRNAEVITPTSS*KPKIRGTN*KLDCQ
KGTASVIECTAFSAFSNNNSKS*SVSSNTHIFS
TDCSYY*FLEQQ*EPSYRKQLFT**FSSCIKSGL
NLQWTKYQQLISSFYPTSCWAESGSTRLRSEWS
SAGQWRDSGGTS*WNAACNFHHSCRVCSGWNNW
SFAR*PTGN*WHCRSFKWGYADSCHNVPEPYPSH
PHNRTT*CNTSNASYTD*QCLRTRITF*PATTN
TYSSTAVSAVVKFSTAHTSTQAPPLHTATTNPF
LTIHGDNASQKVARLSDKTGPVAQEKS*HLRNI*
KLPILLF*HFIWLPLQSFYYSYEETQQETQCTT
KD*LLQGHSCKALISFLVALLH*NGIPMPLPLT
PVF*TWKENLITF*SDIIYMQYVYQLKNLI*LVH
N*FCL*IGDANSKTKYLLHLQTT*FYCTS*NML
FCLGYSMLALSQIPRN*FLLLELH*FSITNI*H
ITWDLAIFVKKKFPF*WDLANFGNEVRMVMSASA
KGNFLLRIAFFSVKTYSYFEEILS*VSSEAAGG
TRSIQS*ILLSERGHCGKCWWGLPLIKCLHCAA
RAVDSRVGQSVLRAAGIIPSPAAFPCFRLYSELS
VPL*IAQAKLLPGYLSTNESQEKEWIW*E*RFV
LFKPLPITDH*KLTTRVPETGETCMTALPLWGA
TLLM*QYRRVIPPLRMSSSNSSLVCELLVEKTQL
*LDLHCVLSWKNMLILQYVSWLNIAQFLPHFCK
*SFVNLFCIVTNS*DNIDILICNISNW*I*LKS
KINLFLYVQGNFKVKSFVDNLKNQCGLFYLFNPL
VVIL*QFV*MVNFECVVILPRCKIPHVLKCTKC
FVNKI**C

Sequence NM_004641

CGCGCACGCAGGGCTAGCCTCGCCCAGGCCTCCTCCCTCACGCCGGCCGCAGGACGGGCGCGCACGCCAAGTGACGCTCCGAGGAGGAAGCGCAGCCCCC
TTCCCCTCCCTCGCTGCCCCTGGCCCAGCGGGAGCCCCCCCTCCCCCCAGTGCGCCTGTGCGGAGGCCCTCTTGATTATGTGTGCCCTCTCCGGGCGCCC
GCGTTAGCGGCCGGGTGGAGGTGGGGAGGGAAGACGCTGAGGAGGAGGAGGAGGCGGAGGAGGCGGTGGAGGGGAGGTGGGGGGAATCAGCAAGGACATG
GCTCCTGACTCCTGTGCGGAACGTGAGTGACTGAGCGGCAAAGCCCGAATGGTCTCTAGCGACCGGCCCGTGTCACTGGAGGACGAGGTCTCCCATAGTA
TGAAGGAGATGATTGGAGGCTGTTGCGTTTGCTCAGACGAGAGAGGCTGGGCCGAGAACCCGCTGGTTTATTGCGACGGGCACGGCTGCAGCGTCGCGGT
GCATCAAGCTTGCTATGGCATTGTTCAAGTACCCACTGGACCGTGGTTTTGCAGGAAATGTGAATCTCAGGAGAGAGCAGCCAGAGTGAGATGTGAACTT
TGTCCCCATAAGGATGGAGCTTTAAAAAGAACAGATAATGGGGGTTGGGCCCATGTGGTTTGTGCCCTGTATATTCCAGAGGTACAATTTGCCAATGTTT
CCACAATGGAACCAATTGTTTTACAGTCTGTTCCGCATGATCGTTATAATAAGACTTGCTACATTTGTGATGAACAAGGAAGAGAAAGCAAAGCAGCCAC
TGGTGCTTGCATGACATGTAATAAACATGGATGTCGACAGGCTTTCCATGTAACATGCGCTCAGTTTGCCGGACTGCTTTGTGAAGAAGAAGGTAATGGT
GCCGATAATGTCCAATACTGTGGCTACTGTAAATACCATTTTAGTAAGCTGAAAAAGAGCAAACGGGGATCTAATAGGTCATATGATCAAAGTTTAAGTG
ATTCTTCCTCTCACTCTCAGGATAAACATCATGAGAAAGAGAAAAAAAAATATAAAGAGAAGGACAAACACAAACAGAAACACAAGAAGCAGCCAGAACC
ATCACCTGCATTGGTTCCATCCTTGACTGTTACTACAGAAAAAACTTATACAAGCACTAGCAACAACTCTATATCTGGATCATTGAAGCGCTTGGAAGAT
ACTACTGCACGATTTACAAATGCAAATTTCCAGGAAGTCTCTGCACACACCTCTAGTGGAAAAGATGTTTCAGAGACTAGAGGGTCAGAGGGCAAAGGGA
AGAAATCTTCAGCTCACAGCTCAGGTCAAAGGGGAAGAAAGCCTGGTGGTGGAAGAAATCCAGGAACAACTGTGTCAGCAGCTAGCCCTTTTCCTCAAGG
CAGTTTTTCAGGAACTCCAGGCAGTGTAAAGTCATCTTCTGGAAGTTCAGTGCAGTCTCCCCAGGATTTCCTGAGCTTTACAGACTCAGATCTGCGTAAT
GACAGTTACTCTCACTCCCAACAGTCATCAGCAACCAAAGATGTACATAAAGGAGAGTCTGGAAGCCAGGAAGGGGGGGTAAATAGTTTTAGTACCTTAA
TTGGCCTCCCTTCAACCTCAGCTGTTACTTCACAGCCTAAAAGCTTTGAAAATTCACCTGGAGATTTGGGTAATTCCAGCCTTCCTACAGCAGGATATAA
GCGGGCTCAAACTTCTGGCATAGAAGAAGAAACTGTAAAGGAAAAGAAAAGGAAAGGAAATAAACAAAGTAAGCATGGGCCTGGCAGACCCAAAGGAAAC
AAAAATCAAGAGAATGTTTCTCATCTCTCAGTTTCTTCTGCTTCACCAACATCATCTGTAGCATCAGCTGCAGGAAGCATAACAAGCTCTAGTCTGCAGA
AATCTCCTACATTGCTCAGGAATGGAAGTTTACAGAGCCTCAGTGTTGGCTCATCTCCAGTTGGTTCAGAAATTTCCATGCAGTATCGGCATGATGGAGC
TTGCCCAACAACTACGTTCTCAGAGTTGCTGAATGCAATACACAACGACAGAGGTGACAGTTCTACACTAACAAAGCAAGAACTTAAATTCATAGGTATT
TATAACAGCAATGATGTAGCAGTATCGTTTCCAAATGTAGTATCTGGCTCGGGATCTAGTACTCCTGTCTCCAGCTCTCACTTACCTCAGCAGTCTTCTG
GGCATTTGCAACAAGTAGG
AGCGCTCTCTCCCTCAGCTGTGTCATCTGCAGCCCCTGCTGTTGCTACAACTCAGGCAAATACTCTATCTGGATCTTCTCT
CAGTCAGGCACCATCTCATATGTATGGCAATAGATCAAATTCATCAATGGCAGCTCTTATAGCTCAGTCTGAAAACAATCAAACAGATCAAGATCTTGGA
GACAATAGCCGCAACCTAGTTGGCAGAGGAAGCTCACCCCGAGGAAGTCTCTCGCCACGATCCCCTGTAAGCAGCTTACAGATTCGCTATGATCAACCAG
GCAACAGCAGTTTGGAAAATCTGCCTCCAGTAGCAGCCAGCATAGAACAGCTTTTGGAGAGGCAGTGGAGTGAAGGACAGCAATTTTTACTAGAACAGGG
TACTCCTAGTGACATTTTAGGAATGCTGAAGTCATTACACCAACTTCAAGTTGAAAACCGAAGATTAGAGGAACAAATTAAAAACTTGACTGCCAAAAAG
GAACGGCTTCAGTTATTGAATGCACAGCTTTCAGTGCCTTTTCCAACAATAACAGCAAATCCTAGTCCGTCTCATCAAATACACACATTTTCAGCACAGA
CTGCTCCTACTACTGATTCCTTGAACAGCAGTAAGAGCCCTCATATAGGAAACAGCTTTTTACCTGATAATTCTCTTCCTGTATTAAATCAGGACTTAAC
CTCCAGTGGACAAAGTACCAGCAGCTCATCAGCTCTTTCTACCCCACCTCCTGCTGGGCAGAGTCCGGCTCAACAAGGCTCAGGAGTGAGTGGAGTTCAG
CAGGTCAATGGCGTGACAGTGGGGGCACTAGCTAGTGGAATGCAGCCTGTAACTTCCACCATTCCTGCCGTGTCTGCAGTGGGTGGAATAATTGGAGCTT
TGCCAGGTAACCAACTGGCAATTAATGGCATTGTAGGAGCTTTAAATGGGGTTATGCAGACTCCTGTCACAATGTCCCAGAACCCTACCCCTCTCACCCA
CACAACCGTACCACCTAATGCAACACATCCAATGCCAGCTACACTGACTAACAGTGCCTCAGGACTAGGATTACTTTCTGACCAGCAACGACAAATACTT
ATTCATCAACAGCAGTTTCAGCAGTTGTTAAATTCTCAACAGCTCACACCAGTACACAGGCACCCCCACTTCACACAGCTACCACCAACCCATTTCTCAC
CATCCATGGAGATAATGCAAGTCAGAAAGTAGCAAGACTTAGTGATAAAACTGGGCCTGTAGCTCAAGAGAAAAGTTGACACCTGAGAAACATCTAGAAA
TTGCCTATCCTGCTGTTCTAGCACTTCATCTGGCTGCCTTTGCAGTCCTTTTACTACAGCTATGAAGAAACGCAACAAGAAACTCAATGCACAACAAAGG
ATTAATTGCTGCAAGGACATTCTTGTAAGGCTTTGATTAGTTTTCTTGTTGCTTTGTTGCACTGAAATGGAATTCCCATGCCCCTACCCCTTACCCCAGT
TTTTTGAACATGGAAAGAAAATTTAATAACTTTTTAAAGTGACATAATTTACATGCAATATGTTTATCAACTCAAGAATTTAATATAGTTGGTACACAAC
TAGTTTTGTTTATAAATTGGAGATGCAAATAGCAAAACTAAATACTTGCTCCATTTACAAACTACTTGATTTTATTGTACAAGTTGAAATATGCTCTTTT
GTTTGGGTTACAGTATGCTTGCTCTAAGTCAAATTCCAAGGAACTAATTTCTTCTCCTGGAGTTGCATTGATTCAGTATTACAAATATATAGCACATCAC
CTGGGACTTGGCAATCTTTGTTAAAAAAAAATTTCCTTTCTAATGGGATTTGGCCAATTTTGGTAATGAAGTTAGGATGGTAATGTCTGCATCTGCTAAA
GGTAATTTTCTTTTGAGAATTGCTTTCTTTAGTGTTAAGACCTACTCATATTTTGAAGAAATCTTGAGTTAAGTGAGTTCTGAGGCTGCTGGGGGAACCA
GATCAATTCAAAGCTAAATACTTCTTTCAGAAAGGGGCCACTGTGGAAAGTGCTGGTGGGGTTTGCCCTTGATCAAGTGCCTCCATTGTGCTGCAAGGGC
TGTAGACAGCAGGGTGGGACAGTCAGTCCTCCGAGCAGCAGGAATCATCCCGTCACCTGCAGCCTTCCCATGCTTCCGCCTTTATTCAGAACTTTCTGTG
CCACTGTAGATAGCTCAGGCAAAACTATTACCTGGGTATTTATCCACTAATGAGTCACAAGAAAAGGAGTGGATTTGGTAAGAATAGAGATTTGTTTTAT
TTAAACCACTTCCCATTACTGACCATTAAAAGCTCACCACTAGAGTTCCTGAAACAGGTGAAACCTGTATGACAGCCCTTCCACTTTGGGGAGCCACGCT
TTTGATGTGACAGTACCGCAGAGTGATTCCCCCACTGAGGATGTCATCATCAAACTCTTCTTTGGTGTGTGAATTATTAGTGGAAAAGACCCAGCTGTAA
TTAGACCTCCACTGTGTACTTAGCTGGAAGAACATGTTAATTCTGCAATATGTTTCTTGGTTAAACATTGCACAGTTCTTACCTCATTTCTGTAAATAAA
GTTTTGTGAATCTGTTTTGTATTGTGACAAATTCATAAGATAACATTGATATTTTGATTTGTAATATTTCTAATTGGTAGATTTAATTGAAAAGTAAAAT
TAATTTATTTTTATATGTTCAGGGGAATTTTAAAGTCAAATCTTTTGTAGATAATTTAAAAAATCAGTGTGGTTTATTTTACTTATTTAACCCACTGGTT
GTTATTCTGTAACAGTTTGTATAAATGGTAAATTTTGAATGTGTTGTTATTTTACCTAGATGTAAAATTCCACATGTATTAAAATGTACAAAATGTTTTG
TTAATAAAATTTAATAATGTT
  • refseq_MLLT10.F1 (forward primer)
  • refseq_MLLT10.R1 (reverse primer)
  • Single exon skipping

Frame 0

RARRASLAQASSLTPAAGRARTPSDAPRRKRSP
LPLPRCPWPSGSPPSPQCACAEALLIMCALSGRP
R*RPGGGGEGRR*GGGGGGGGGGGEVGGISKDM
APDSCAERE*LSGKARMVSSDRPVSLEDEVSHS
MKEMIGGCCVCSDERGWAENPLVYCDGHGCSVAV
HQACYGIVQVPTGPWFCRKCESQERAARVRCEL
CPHKDGALKRTDNGGWAHVVCALYIPEVQFANV
STMEPIVLQSVPHDRYNKTCYICDEQGRESKAAT
GACMTCNKHGCRQAFHVTCAQFAGLLCEEEGNG
ADNVQYCGYCKYHFSKLKKSKRGSNRSYDQSLS
DSSSHSQDKHHEKEKKKYKEKDKHKQKHKKQPEP
SPALVPSLTVTTEKTYTSTSNNSISGSLKRLED
TTARFTNANFQEVSAHTSSGKDVSETRGSEGKG
KKSSAHSSGQRGRKPGGGRNPGTTVSAASPFPQG
SFSGTPGSVKSSSGSSVQSPQDFLSFTDSDLRN
DSYSHSQQSSATKDVHKGESGSQEGGVNSFSTL
IGLPSTSAVTSQPKSFENSPGDLGNSSLPTAGYK
RAQTSGIEEETVKEKKRKGNKQSKHGPGRPKGN
KNQENVSHLSVSSASPTSSVASAAGSITSSSLQ
KSPTLLRNGSLQSLSVGSSPVGSEISMQYRHDGA
CPTTTFSELLNAIHNDRGDSSTLTKQELKFIGI
YNSNDVAVSFPNVVSGSGSSTPVSSSHLPQQSS
GHLQQVG
ALSPSAVSSAAPAVATTQANTLSGSSL
SQAPSHMYGNRSNSSMAALIAQSENNQTDQDLG
DNSRNLVGRGSSPRGSLSPRSPVSSLQIRYDQP
GNSSLENLPPVAASIEQLLERQWSEGQQFLLEQG
TPSDILGMLKSLHQLQVENRRLEEQIKNLTAKK
ERLQLLNAQLSVPFPTITANPSPSHQIHTFSAQ
TAPTTDSLNSSKSPHIGNSFLPDNSLPVLNQDLT
SSGQSTSSSSALSTPPPAGQSPAQQGSGVSGVQ
QVNGVTVGALASGMQPVTSTIPAVSAVGGIIGA
LPGNQLAINGIVGALNGVMQTPVTMSQNPTPLTH
TTVPPNATHPMPATLTNSASGLGLLSDQQRQIL
IHQQQFQQLLNSQQLTPVHRHPHFTQLPPTHFS
PSMEIMQVRK*QDLVIKLGL*LKRKVDT*ETSRN
CLSCCSSTSSGCLCSPFTTAMKKRNKKLNAQQR
INCCKDILVRL*LVFLLLCCTEMEFPCPYPLPQ
FFEHGKKI**LFKVT*FTCNMFINSRI*YSWYTT
SFVYKLEMQIAKLNTCSIYKLLDFIVQVEICSF
VWVTVCLL*VKFQGTNFFSWSCIDSVLQIYSTS
PGTWQSLLKKNFLSNGIWPILVMKLGW*CLHLLK
VIFF*ELLSLVLRPTHILKKS*VK*VLRLLGEP
DQFKAKYFFQKGATVESAGGVCP*SSASIVLQG
L*TAGWDSQSSEQQESSRHLQPSHASAFIQNFLC
HCR*LRQNYYLGIYPLMSHKKRSGFGKNRDLFY
LNHFPLLTIKSSPLEFLKQVKPV*QPFHFGEPR
F*CDSTAE*FPH*GCHHQTLLWCVNY*WKRPSCN
*TSTVYLAGRTC*FCNMFLG*TLHSSYLISVNK
VL*ICFVL*QIHKITLIF*FVIFLIGRFN*KVK
LIYFYMFRGILKSNLL*II*KISVVYFTYLTHWL
LFCNSLYKW*ILNVLLFYLDVKFHMY*NVQNVL
LIKFNNV

Frame 1

AHAGLASPRPPPSRRPQDGRARQVTLRGGSAAP
FPSLAAPGPAGAPPPPSAPVRRPS*LCVPSPGA
RVSGRVEVGREDAEEEEEAEEAVEGRWGESARTW
LLTPVRNVSD*AAKPEWSLATGPCHWRTRSPIV
*RR*LEAVAFAQTREAGPRTRWFIATGTAAASR
CIKLAMALFKYPLDRGFAGNVNLRREQPE*DVNF
VPIRMEL*KEQIMGVGPMWFVPCIFQRYNLPMF
PQWNQLFYSLFRMIVIIRLATFVMNKEEKAKQP
LVLA*HVINMDVDRLSM*HALSLPDCFVKKKVMV
PIMSNTVATVNTILVS*KRANGDLIGHMIKV*V
ILPLTLRINIMRKRKKNIKRRTNTNRNTRSSQN
HHLHWFHP*LLLQKKLIQALATTLYLDH*SAWKI
LLHDLQMQISRKSLHTPLVEKMFQRLEGQRAKG
RNLQLTAQVKGEESLVVEEIQEQLCQQLALFLK
AVFQELQAV*SHLLEVQCSLPRIS*ALQTQICVM
TVTLTPNSHQQPKMYIKESLEARKGG*IVLVP*
LASLQPQLLLHSLKALKIHLEIWVIPAFLQQDI
SGLKLLA*KKKL*RKRKGKEINKVSMGLADPKET
KIKRMFLISQFLLLHQHHL*HQLQEA*QALVCR
NLLHCSGMEVYRASVLAHLQLVQKFPCSIGMME
LAQQLRSQSC*MQYTTTEVTVLH*QSKNLNS*VF
ITAMM*QYRFQM*YLARDLVLLSPALTYLSSLL
GICNK*
ERSLPQLCHLQPLLLLQLRQILYLDLL
SVRHHLICMAIDQIHQWQLL*LSLKTIKQIKILE
TIAAT*LAEEAHPEEVSRHDPL*AAYRFAMINQ
ATAVWKICLQ*QPA*NSFWRGSGVKDSNFY*NR
VLLVTF*EC*SHYTNFKLKTED*RNKLKT*LPKR
NGFSY*MHSFQCLFQQ*QQILVRLIKYTHFQHR
LLLLLIP*TAVRALI*ETAFYLIILFLY*IRT*
PPVDKVPAAHQLFLPHLLLGRVRLNKAQE*VEFS
RSMA*QWGH*LVECSL*LPPFLPCLQWVE*LEL
CQVTNWQLMAL*EL*MGLCRLLSQCPRTLPLSP
TQPYHLMQHIQCQLH*LTVPQD*DYFLTSNDKYL
FINSSFSSC*ILNSSHQYTGTPTSHSYHQPISH
HPWR*CKSESSKT***NWACSSREKLTPEKHLE
IAYPAVLALHLAAFAVLLLQL*RNATRNSMHNKG
LIAARTFL*GFD*FSCCFVALKWNSHAPTPYPS
FLNMERKFNNFLK*HNLHAICLSTQEFNIVGTQ
LVLFINWRCK*QN*ILAPFTNYLILLYKLKYALL
FGLQYACSKSNSKELISSPGVALIQYYKYIAHH
LGLGNLC*KKISFLMGFGQFW**S*DGNVCIC*
R*FSFENCFL*C*DLLIF*RNLELSEF*GCWGNQ
INSKLNTSFRKGPLWKVLVGFALDQVPPLCCKG
CRQQGGTVSPPSSRNHPVTCSLPMLPPLFRTFC
ATVDSSGKTITWVFIH**VTRKGVDLVRIEICFI
*TTSHY*PLKAHH*SS*NR*NLYDSPSTLGSHA
FDVTVPQSDSPTEDVIIKLFFGV*IISGKDPAV
IRPPLCT*LEEHVNSAICFLVKHCTVLTSFL*IK
FCESVLYCDKFIR*H*YFDL*YF*LVDLIEK*N
*FIFICSGEF*SQIFCR*FKKSVWFILLI*PTG
CYSVTVCINGKF*MCCYFT*M*NSTCIKMYKMFC
**NLIM

Frame 2

RTQG*PRPGLLPHAGRRTGAHAK*RSEEEAQPP
SPPSLPLAQREPPLPPVRLCGGPLDYVCPLRAP
ALAAGWRWGGKTLRRRRRRRRRWRGGGGNQQGH
GS*LLCGT*VTERQSPNGL*RPARVTGGRGLP*Y
EGDDWRLLRLLRRERLGREPAGLLRRARLQRRG
ASSLLWHCSSTHWTVVLQEM*ISGESSQSEM*T
LSP*GWSFKKNR*WGLGPCGLCPVYSRGTICQCF
HNGTNCFTVCSA*SL**DLLHL**TRKRKQSSH
WCLHDM**TWMSTGFPCNMRSVCRTAL*RRR*W
CR*CPILWLL*IPF**AEKEQTGI**VI*SKFK*
FFLSLSG*TS*EREKKI*REGQTQTETQEAART
ITCIGSILDCYYRKNLYKH*QQLYIWIIEALGR
YYCTIYKCKFPGSLCTHL*WKRCFRD*RVRGQRE
EIFSSQLRSKGKKAWWWKKSRNNCVSS*PFSSR
QFFRNSRQCKVIFWKFSAVSPGFPELYRLRSA*
*QLLSLPTVISNQRCT*RRVWKPGRGGK*F*YLN
WPPFNLSCYFTA*KL*KFTWRFG*FQPSYSRI*
AGSNFWHRRRNCKGKEKERK*TK*AWAWQTQRK
QKSRECFSSLSFFCFTNIICSISCRKHNKL*SAE
ISYIAQEWKFTEPQCWLISSWFRNFHAVSA*WS
LPNNYVLRVAECNTQRQR*QFYTNKART*IHRY
L*QQ*CSSIVSKCSIWLGI*YSCLQLSLTSAVFW
AFATSR
SALSLSCVICSPCCCYNSGKYSIWIFS
QSGTISYVWQ*IKFINGSSYSSV*KQSNRSRSW
RQ*PQPSWQRKLTPRKSLATIPCKQLTDSL*STR
QQQFGKSASSSSQHRTAFGEAVE*RTAIFTRTG
YS**HFRNAEVITPTSS*KPKIRGTN*KLDCQK
GTASVIECTAFSAFSNNNSKS*SVSSNTHIFSTD
CSYY*FLEQQ*EPSYRKQLFT**FSSCIKSGLN
LQWTKYQQLISSFYPTSCWAESGSTRLRSEWSS
AGQWRDSGGTS*WNAACNFHHSCRVCSGWNNWSF
AR*PTGN*WHCRSFKWGYADSCHNVPEPYPSHP
HNRTT*CNTSNASYTD*QCLRTRITF*PATTNT
YSSTAVSAVVKFSTAHTSTQAPPLHTATTNPFLT
IHGDNASQKVARLSDKTGPVAQEKS*HLRNI*K
LPILLF*HFIWLPLQSFYYSYEETQQETQCTTK
D*LLQGHSCKALISFLVALLH*NGIPMPLPLTPV
F*TWKENLITF*SDIIYMQYVYQLKNLI*LVHN
*FCL*IGDANSKTKYLLHLQTT*FYCTS*NMLF
CLGYSMLALSQIPRN*FLLLELH*FSITNI*HIT
WDLAIFVKKKFPF*WDLANFGNEVRMVMSASAK
GNFLLRIAFFSVKTYSYFEEILS*VSSEAAGGT
RSIQS*ILLSERGHCGKCWWGLPLIKCLHCAARA
VDSRVGQSVLRAAGIIPSPAAFPCFRLYSELSV
PL*IAQAKLLPGYLSTNESQEKEWIW*E*RFVL
FKPLPITDH*KLTTRVPETGETCMTALPLWGATL
LM*QYRRVIPPLRMSSSNSSLVCELLVEKTQL*
LDLHCVLSWKNMLILQYVSWLNIAQFLPHFCK*
SFVNLFCIVTNS*DNIDILICNISNW*I*LKSKI
NLFLYVQGNFKVKSFVDNLKNQCGLFYLFNPLV
VIL*QFV*MVNFECVVILPRCKIPHVLKCTKCF
VNKI**C

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