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Sequences

Sequence NM_017751

TTTCGGCGCCGTGGCGGAATGGCGGCTTCCATCTCTGAGGCGAGCGACGCTATGGATCCCACAGTGGTTTGCTAAGAAGGCCATTTTCAACTCTCCACTG GAGGCTGCTATGGCGTTCCCTCACCTGCAGCAGCCCAGCTTTCTACTGGCTAGCCTGAAAGCTGACTCTATAAATAAGCCCTTTGCACAGCAGTGCCAAG ACTTGGTTAAAGTCATTGAGGACTTTCCAGCAAAGGAGCTGCACACCATCTTCCCATGGCTGGTAGAAAGCATTTTTGGCAGCCTAGATGGTGTCCTCGT TGGCTGGAACCTCCGCTGCTTACAGGGGCGCGTGAATCCTGTGGAGTACAGCATCGTGATGGAATTTCTCGACCCTGGTGGCCCAATGATGAAGTTGGTT TATAAGCTTCAAGCTGAAGACTATAAGTTCGACTTTCCTGTCTCCTACTTGCCTGGTCCTGTGAAGGCGTCCATCCAGGAGTGCATCCTCCCTGACAGTC CTCTGTACCACAACAAGGTCCAGTTCACCCCTACTGGGGGCCTTGGTCTGAACTTGGCCCTGAATCCGTTCGAGTATTACATATTCTTCTTTGCCTTGAG CCTCATCACTCAGAAGCCACTTCCTGTGTCCCTCCACGTCCGTACTTCAGACTGTGCCTATTTCATCCTGGTGGACAGGTACCTGTCATGGTTCCTGCCC ACCGAAGGCAGTGTGCCCCCACCACTCTCCTCCAGCCCAGGGGGGACCAGCCCCTCACCACCTCCCAGGACACCAGCCATACCCTTTGCTTCCTATGGCC TCCACCACACTAGCCTCCTAAAGCGACACATCTCTCATCAGACGTCTGTGAATGCAGACCCCGCCTCCCACGAGATCTGGAGGTCAGAAACTCTGCTCCA GGTTTTTGTTGAAATGTGGCTTCATCACTATTCCTTGGAGATGTATCAAAAAATGCAGTCCCCTCATGCCAAGGAGTCGTTCACGCCTACTGAGGAGCAT GTGTTGGTGGTGCGCCTGCTGCTGAAGCACCTGCACGCCTTTGCCAACAGCCTGAAGCCAGAGCAGGCCTCACCCTCCGCCCACTCCCACGCCACCAGCC CCCTGGAGGAGTTCAAACGGGCTGCTGTCCCGAGGTTCGTCCAGCAGAAACTCTACCTCTTCTTGCAGCATTGCTTTGGCCACTGGCCCCTGGACGCATC GTTCAGAGCTGTCCTGGAGATGTGGCTGAGCTACCTGCAGCCGTGGCGGTACGCGCCTGACAAGCAGGCTCCGGGCAGCGACTCCCAGCCCCGGTGTGTG TCGGAGAAATGGGCACCCTTTGTCCAGGAGAACCTGCTGATGTACACCAAGTTGTTTGTGGGCTTTCTGAACCGCGCGCTCCGCACAGACCTGGTCAGCC CCAAGCACGCGCTCATGGTGTTCCGAGTGGCCAAAGTCTTTGCCCAGCCCAACCTGGCTGAGATGATTCAGAAAGGTGAGCAGCTATTCCTGGAGCCAGA GCTGGTCATCCCCCACCGCCAGCACCGACTCTTCACGGCCCCCACATTCACTGGGAGCTTCCTGTCACCCTGGCCACCAGCGGTCACTGATGCCTCCTTC AAGGTGAAGAGCCACGTCTACAGCCTGGAGGGCCAGGACTGCAAGTACACCCCGATGTTTGGGCCCGAGGCCCGCACCCTGGTCCTGCGCCTCGCTCAGC TCATCACACAGGCCAAACACACAGCCAAGTCCATCTCCGACCAGTGTGCGGAGAGCCCGGCTGGCCACTCCTTCCTCTCATGGCTGGGCTTTAGCTCCAT GGACACCAATGGCTCCTACACAGCCAACGACCTGGACGAGATGGGGCAAGACAGTGTCCGGAAGACAGATGAATACCTGGAGAAGGCCCTGGAGTACCTG CGCCAGATATTCCGGCTCAGCGAAGCGCAGCTCAGGCAGTTCACACTCGCCTTGGGCACCACCCAGGATGAGAATGGAAAAAAGCAACTCCCCGACTGCA TCGTGGGTGAGGACGGACTCATCCTTACGCCCCTGGGGCGGTACCAGATCATCAATGGGCTGCGAAGGTTTGAAATTGAGTACCAGGGGGACCCGGAGCT GCAGCCCATCCGGAGCTATGAGATCGCCAGCTTGGTCCGCACACTCTTTAGGCTGTCGTCTGCCATCAACCACAGATTTGCAGGACAGATGGCGGCTCTG TGTTCCCGGGATGACTTCCTCGGCAGCTTCTGTCGCTACCACCTCACAGAACCTGGGCTGGCCAGCAGGCACCTGCTGAGCCCTGTGGGGCGGAGGCAGG TGGCCGGCCACACCCGCGGCCCCAGGCTCAGCCTGCGCTTCCTGGGCAGTTACCGGACGCTGGTCTCGCTGCTGCTGGCCTTCTTCGTGGCCTCTCTGTT CTGCGTCGGGCCCCTCCCATGCACGCTGCTGCTCACCCTGGGCTATGTCCTCTACGCCTCTGCCATGACACTGCTGACCGAGCGGGGGAAGCTGCACCAG CCCTGAAGGTGTCAGCTGCCTTCAGAGCAGGCTGGAGGGATTTGCCACACAGCCCCACCCTTGGGCTGAGAGGACCTGGGAAGCCCCTCCAGGAGGGAAC ACGGTCATCCTCGGGCTTCTGGAGCGGGGTTCCTGCAGCCGCAGAGGCATCTGGAGGAAACGCAACCAAGAAAGGAAGGCAGGTGGGCCCCAGCAAAGGA GTAGCTGCCAGGGCTCAACAGCTACGCTCTGTGACAGCGCAGAGCTCAGCGGCGGCCTTTCCCTCCCTCCGCCAAGGACTCACGGCCAAGCCAGCTCTCG GGGCCTTTTTTCCACTGCCCATTTGGCTACTCTGCTGCACCAAGCTTGGGAGCCAGCCTGCCAACAGCCACCTGGGCCTGGCCTCCCCACTGGCTGGCCT TGAGGTTGGCAGAGTGGGTTGTGGCGCTTCCTCTCTCTGTGTGGGACCAGGACAGTGGCTTAAGTCTCCACTCCAGGAAAGAATCAAAGTTTCTAGAGTT GTGAGAAAACCAGAGAGTGGCTGTCCTGATTCTTCACTGTGAGGGGCGTTCTTCATGTTCTCCCAGCTGTTCCAAGACTGGGCCGTAGAATTCCATGTTT CAGGAGCCTAAGACCCTCCCAGAGCCCAGGGGCTTCACCGCAGACCCCAAGCCATTGAGCACATCACCCAAAGCAGTGGCCAACATCGCGGACCCCTGTG CCTTGTCACAGATGGGTGCTGGTCCTCAGGCGTTGGGGACACTGCTGGGTCGATGGGGTCGGATTCTGCCAGTTTCTGCTCTGCAGCCAAAGATGGTCAG AAGCATTGTCACTTCAGTAACATCAAGTGCTCAAAGACATGGCAACCGTTCAGTGGTACTTAAGTATTCAAAATATACAACTACAGATTCTCTGACAGAA ACCAGCACGGGGTCTTCACCTTCATTCACCCCACAGGCGACATGCGAGGGAGAACAGCATCTCAGTGGTGATTTCCAAACCAAGCCTTTGTTTTCGGTGT GGGGTTTTGGGGGTTTGCTTTAATGTTTTTGAAATTGTAAATGTTGGGCTTTGTATTTTGATGTAAACTGAGCATAATGGCATTTTAGGGCCTGTGACCA AAAATGAAGCTTGTAACGACCATGGATCTGAATAAACATGTCCTTGCTTCTGA

refseq_SMPD4.F4 (forward primer)
refseq_SMPD4.R4 (reverse primer)
Single exon skipping

Frame 0

FRRRGGMAASISEASDAMDPTVVC*EGHFQLST GGCYGVPSPAAAQLSTG*PES*LYK*ALCTAVPR LG*SH*GLSSKGAAHHLPMAGRKHFWQPRWCPR WLEPPLLTGARESCGVQHRDGISRPWWPNDEVG L*ASS*RL*VRLSCLLLAWSCEGVHPGVHPP*QS SVPQQGPVHPYWGPWSELGPESVRVLHILLCLE PHHSEATSCVPPRPYFRLCLFHPGGQVPVMVPA HRRQCAPTTLLQPRGDQPLTTSQDTSHTLCFLWP PPH*PPKATHLSSDVCECRPRLPRDLEVRNSAP GFC*NVASSLFLGDVSKNAVPSCQGVVHAY*GA CVGGAPAAEAPARLCQQPEARAGLTLRPLPRHQP PGGVQTGCCPEVRPAETLPLLAALLWPLAPGRI VQSCPGDVAELPAAVAVRA*QAGSGQRLPAPVC VGEMGTLCPGEPADVHQVVCGLSEPRAPHRPGQP QARAHGVPSGQSLCPAQPG*DDSER*AAIPGAR AGHPPPPAPTLHGPHIHWELPVTLATSGH*CLL QGEEPRLQPGGPGLQVHPDVWARGPHPGPAPRSA HHTGQTHSQVHLRPVCGEPGWPLLPLMAGL*LH GHQWLLHSQRPGRDGARQCPEDR*IPGEGPGVP APDIPAQRSAAQAVHTRLGHHPG*EWKKATPRLH RG*GRTHPYAPGAVPDHQWAAKV*N*VPGGPGA AAHPEL*DRQLGPHTL*AVVCHQPQICRTDGGS VFPG*LPRQLLSLPPHRTWAGQQAPAEPCGAEAG GRPHPRPQAQPALPGQLPDAGLAAAGLLRGLSV LRRAPPMHAAAHPGLCPLRLCHDTADRAGEAAP ALKVSAAFRAGWRDLPHSPTLGLRGPGKPLQEGT RSSSGFWSGVPAAAEASGGNATKKGRQVGPSKG VAARAQQLRSVTAQSSAAAFPSLRQGLTAKPAL GAFFPLPIWLLCCTKLGSQPANSHLGLASPLAGL EVGRVGCGASSLCVGPGQWLKSPLQERIKVSRV VRKPESGCPDSSL*GAFFMFSQLFQDWAVEFHV SGA*DPPRAQGLHRRPQAIEHITQSSGQHRGPLC LVTDGCWSSGVGDTAGSMGSDSASFCSAAKDGQ KHCHFSNIKCSKTWQPFSGT*VFKIYNYRFSDR NQHGVFTFIHPTGDMRGRTASQW*FPNQAFVFGV GFWGFALMFLKL*MLGFVF*CKLSIMAF*GL*P KMKLVTTMDLNKHVLAS

Frame 1

FGAVAEWRLPSLRRATLWIPQWFAKKAIFNSPL EAAMAFPHLQQPSFLLASLKADSINKPFAQQCQ DLVKVIEDFPAKELHTIFPWLVESIFGSLDGVLV GWNLRCLQGRVNPVEYSIVMEFLDPGGPMMKLV YKLQAEDYKFDFPVSYLPGPVKASIQECILPDS PLYHNKVQFTPTGGLGLNLALNPFEYYIFFFALS LITQKPLPVSLHVRTSDCAYFILVDRYLSWFLP TEGSVPPPLSSSPGGTSPSPPPRTPAIPFASYG LHHTSLLKRHISHQTSVNADPASHEIWRSETLLQ VFVEMWLHHYSLEMYQKMQSPHAKESFTPTEEH VLVVRLLLKHLHAFANSLKPEQASPSAHSHATS PLEEFKRAAVPRFVQQKLYLFLQHCFGHWPLDAS FRAVLEMWLSYLQPWRYAPDKQAPGSDSQPRCV SEKWAPFVQENLLMYTKLFVGFLNRALRTDLVS PKHALMVFRVAKVFAQPNLAEMIQKGEQLFLEPE LVIPHRQHRLFTAPTFTGSFLSPWPPAVTDASF KVKSHVYSLEGQDCKYTPMFGPEARTLVLRLAQ LITQAKHTAKSISDQCAESPAGHSFLSWLGFSSM DTNGSYTANDLDEMGQDSVRKTDEYLEKALEYL RQIFRLSEAQLRQFTLALGTTQDENGKKQLPDC IVGEDGLILTPLGRYQIINGLRRFEIEYQGDPEL QPIRSYEIASLVRTLFRLSSAINHRFAGQMAAL CSRDDFLGSFCRYHLTEPGLASRHLLSPVGRRQ VAGHTRGPRLSLRFLGSYRTLVSLLLAFFVASLF CVGPLPCTLLLTLGYVLYASAMTLLTERGKLHQ P*RCQLPSEQAGGICHTAPPLG*EDLGSPSRRE HGHPRASGAGFLQPQRHLEETQPRKEGRWAPAKE *LPGLNSYAL*QRRAQRRPFPPSAKDSRPSQLS GPFFHCPFGYSAAPSLGASLPTATWAWPPHWLA LRLAEWVVALPLSVWDQDSGLSLHSRKESKFLEL *ENQRVAVLILHCEGRSSCSPSCSKTGP*NSMF QEPKTLPEPRGFTADPKPLSTSPKAVANIADPC ALSQMGAGPQALGTLLGRWGRILPVSALQPKMVR SIVTSVTSSAQRHGNRSVVLKYSKYTTTDSLTE TSTGSSPSFTPQATCEGEQHLSGDFQTKPLFSV WGFGGLL*CF*NCKCWALYFDVN*A*WHFRACDQ K*SL*RPWI*INMSLLL

Frame 2

SAPWRNGGFHL*GERRYGSHSGLLRRPFSTLHW RLLWRSLTCSSPAFYWLA*KLTL*ISPLHSSAK TWLKSLRTFQQRSCTPSSHGW*KAFLAA*MVSS LAGTSAAYRGA*ILWSTAS*WNFSTLVAQ**SWF ISFKLKTISSTFLSPTCLVL*RRPSRSASSLTV LCTTTRSSSPLLGALV*TWP*IRSSITYSSLP* ASSLRSHFLCPSTSVLQTVPISSWWTGTCHGSCP PKAVCPHHSPPAQGGPAPHHLPGHQPYPLLPMA STTLAS*SDTSLIRRL*MQTPPPTRSGGQKLCS RFLLKCGFITIPWRCIKKCSPLMPRSRSRLLRSM CWWCACC*STCTPLPTA*SQSRPHPPPTPTPPA PWRSSNGLLSRGSSSRNSTSSCSIALATGPWTH RSELSWRCG*ATCSRGGTRLTSRLRAATPSPGVC RRNGHPLSRRTC*CTPSCLWAF*TARSAQTWSA PSTRSWCSEWPKSLPSPTWLR*FRKVSSYSWSQ SWSSPTASTDSSRPPHSLGASCHPGHQRSLMPPS R*RATSTAWRARTASTPRCLGPRPAPWSCASLS SSHRPNTQPSPSPTSVRRARLATPSSHGWALAP WTPMAPTQPTTWTRWGKTVSGRQMNTWRRPWSTC ARYSGSAKRSSGSSHSPWAPPRMRMEKSNSPTA SWVRTDSSLRPWGGTRSSMGCEGLKLSTRGTRS CSPSGAMRSPAWSAHSLGCRLPSTTDLQDRWRLC VPGMTSSAASVATTSQNLGWPAGTC*ALWGGGR WPATPAAPGSACASWAVTGRWSRCCWPSSWPLC SASGPSHARCCSPWAMSSTPLP*HC*PSGGSCTS PEGVSCLQSRLEGFATQPHPWAERTWEAPPGGN TVILGLLERGSCSRRGIWRKRNQERKAGGPQQR SSCQGSTATLCDSAELSGGLSLPPPRTHGQASSR GLFSTAHLATLLHQAWEPACQQPPGPGLPTGWP *GWQSGLWRFLSLCGTRTVA*VSTPGKNQSF*S CEKTREWLS*FFTVRGVLHVLPAVPRLGRRIPCF RSLRPSQSPGASPQTPSH*AHHPKQWPTSRTPV PCHRWVLVLRRWGHCWVDGVGFCQFLLCSQRWS EALSLQ*HQVLKDMATVQWYLSIQNIQLQIL*QK PARGLHLHSPHRRHARENSISVVISKPSLCFRC GVLGVCFNVFEIVNVGLCILM*TEHNGILGPVT KNEACNDHGSE*TCPCF*

Sequence NM_017951

ACCACAACAAGGTCCAGTTCACCCCTACTGGGGGCCTTGGTCTGAACTTGGCCCTGAATCCGTTCGAGTATTACATATTCTTCTTTGCCTTGAGCCTCAT CACTCAGAAGCCACTTCCTGTGTCCCTCCACGTCCGTACTTCAGACTGTGCCTATTTCATCCTGGTGGACAGGTACCTGTCATGGTTCCTGCCCACCGAA GGCAGTGTGCCCCCACCACTCTCCTCCAGCCCAGGGGGGACCAGCCCCTCACCACCTCCCAGGACACCAGCCATACCCTTTGCTTCCTATGGCCTCCACC ACACTAGCCTCCTAAAGCGACACATCTCTCATCAGACGTCTGTGAATGCAGACCCCGCCTCCCACGAGATCTGGAGGTCAGAAACTCTGCTCCAGGTTTT TGTTGAAATGTGGCTTCATCACTATTCCTTGGAGATGTATCAAAAAATGCAGTCCCCTCATGCCAAGCTGGAGGTTCTGCACTACCGACTCAGTGTCTCC AGCGCCCTCTACAGCCCCGCCCAACCCAGCCTCCAGGCCCTCCACGCCTACCAAGAGTCGTTCACGCCTACTGAGGAGCATGTGTTGGTGGTGCGCCTGC TGCTGAAGCACCTGCACGCCTTTGCCAACAGCCTGAAGCCAGAGCAGGCCTCACCCTCCGCCCACTCCCACGCCACCAGCCCCCTGGAGGAGTTCAAACG AATGGGGCTGAACCTCCCGGAGGTGCCCAGTGCTCTCCCCCGGCGGAGCCAACCCTCACTGATGGGAGCCCTGGGGTCATCTGTGAGCAGGGCCTCCTTA CTGGGCAAGCAGCAGGTGACCCTCCCCATCCCCTGCAGGGCTGCTGTCCCGAGGTTCGTCCAGCAGAAACTCTACCTCTTCTTGCAGCATTGCTTTGGCC ACTGGCCCCTGGACGCATCGTTCAGAGCTGTCCTGGAGATGTGGCTGAGCTACCTGCAGCCGTGGCGGTACGCGCCTGACAAGCAGGCTCCGGGCAGCGA CTCCCAGCCCCGGTGTGTGTCGGAGAAATGGGCACCCTTTGTCCAGGAGAACCTGCTGATGTACACCAAGTTGTTTGTGGGCTTTCTGAACCGCGCGCTC CGCACAGACCTGGTCAGCCCCAAGCACGCGCTCATGGTGTTCCGAGTGGCCAAAGTCTTTGCCCAGCCCAACCTGGCTGAGATGATTCAGAAAGGTGAGC AGCTATTCCTGGAGCCAGAGCTGGTCATCCCCCACCGCCAGCACCGACTCTTCACGGCCCCCACATTCACTGGGAGCTTCCTGTCACCCTGGCCACCAGC GGTCACTGATGCCTCCTTCAAGGTGAAGAGCCACGTCTACAGCCTGGAGGGCCAGGACTGCAAGTACACCCCGATGTTTGGGCCCGAGGCCCGCACCCTG GTCCTGCGCCTCGCTCAGCTCATCACACAGGCCAAACACACAGCCAAGTCCATCTCCGACCAGTGTGCGGAGAGCCCGGCTGGCCACTCCTTCCTCTCAT GGCTGGGCTTTAGCTCCATGGACACCAATGGCTCCTACACAGCCAACGACCTGGACGAGATGGGGCAAGACAGTGTCCGGAAGACAGATGAATACCTGGA GAAGGCCCTGGAGTACCTGCGCCAGATATTCCGGCTCAGCGAAGCGCAGCTCAGGCAGTTCACACTCGCCTTGGGCACCACCCAGGATGAGAATGGAAAA AAGCAACTCCCCGACTGCATCGTGGGTGAGGACGGACTCATCCTTACGCCCCTGGGGCGGTACCAGATCATCAATGGGCTGCGAAGGTTTGAAATTGAGT ACCAGGGGGACCCGGAGCTGCAGCCCATCCGGAGCTATGAGATCGCCAGCTTGGTCCGCACACTCTTTAGGCTGTCGTCTGCCATCAACCACAGATTTGC AGGACAGATGGCGGCTCTGTGTTCCCGGGATGACTTCCTCGGCAGCTTCTGTCGCTACCACCTCACAGAACCTGGGCTGGCCAGCAGGCACCTGCTGAGC CCTGTGGGGCGGAGGCAGGTGGCCGGCCACACCCGCGGCCCCAGGCTCAGCCTGCGCTTCCTGGGCAGTTACCGGACGCTGGTCTCGCTGCTGCTGGCCT TCTTCGTGGCCTCTCTGTTCTGCGTCGGGCCCCTCCCATGCACGCTGCTGCTCACCCTGGGCTATGTCCTCTACGCCTCTGCCATGACACTGCTGACCGA GCGGGGGAAGCTGCACCAGCCCTGAAGGTGTCAGCTGCCTTCAGAGCAGGCTGGAGGGATTTGCCACACAGCCCCACCCTTGGGCTGAGAGGACCTGGGA AGCCCCTCCAGGAGGGAACACGGTCATCCTCGGGCTTCTGGAGCGGGGTTCCTGCAGCCGCAGAGGCATCTGGAGGAAACGCAACCAAGAAAGGAAGGCA GGTGGGCCCCAGCAAAGGAGTAGCTGCCAGGGCTCAACAGCTACGCTCTGTGACAGCGCAGAGCTCAGCGGCGGCCTTTCCCTCCCTCCGCCAAGGACTC ACGGCCAAGCCAGCTCTCGGGGCCTTTTTTCCACTGCCCATTTGGCTACTCTGCTGCACCAAGCTTGGGAGCCAGCCTGCCAACAGCCACCTGGGCCTGG CCTCCCCACTGGCTGGCCTTGAGGTTGGCAGAGTGGGTTGTGGCGCTTCCTCTCTCTGTGTGGGACCAGGACAGTGGCTTAAGTCTCCACTCCAGGAAAG AATCAAAGTTTCTAGAGTTGTGAGAAAACCAGAGAGTGGCTGTCCTGATTCTTCACTGTGAGGGGCGTTCTTCATGTTCTCCCAGCTGTTCCAAGACTGG GCCGTAGAATTCCATGTTTCAGGAGCCTAAGACCCTCCCAGAGCCCAGGGGCTTCACCGCAGACCCCAAGCCATTGAGCACATCACCCAAAGCAGTGGCC AACATCGCGGACCCCTGTGCCTTGTCACAGATGGGTGCTGGTCCTCAGGCGTTGGGGACACTGCTGGGTCGATGGGGTCGGATTCTGCCAGTTTCTGCTC TGCAGCCAAAGATGGTCAGAAGCATTGTCACTTCAGTAACATCAAGTGCTCAAAGACATGGCAACCGTTCAGTGGTACTTAAGTATTCAAAATATACAAC TACAGATTCTCTGACAGAAACCAGCACGGGGTCTTCACCTTCATTCACCCCACAGGCGACATGCGAGGGAGAACAGCATCTCAGTGGTGATTTCCAAACC AAGCCTTTGTTTTCGGTGTGGGGTTTTGGGGGTTTGCTTTAATGTTTTTGAAATTGTAAATGTTGGGCTTTGTATTTTGATGTAAACTGAGCATAATGGC ATTTTAGGGCCTGTGACCAAAAATGAAGCTTGTAACGACCATGGATCTGAATAAACATGTCCTTGCTTCTGA

refseq_SMPD4.F4 (forward primer)
refseq_SMPD4.R4 (reverse primer)
Single exon skipping

Frame 0

TTTRSSSPLLGALV*TWP*IRSSITYSSLP*AS SLRSHFLCPSTSVLQTVPISSWWTGTCHGSCPPK AVCPHHSPPAQGGPAPHHLPGHQPYPLLPMAST TLAS*SDTSLIRRL*MQTPPPTRSGGQKLCSRF LLKCGFITIPWRCIKKCSPLMPSWRFCTTDSVSP APSTAPPNPASRPSTPTKSRSRLLRSMCWWCAC C*STCTPLPTA*SQSRPHPPPTPTPPAPWRSSN EWG*TSRRCPVLSPGGANPH*WEPWGHL*AGPPY WASSR*PSPSPAGLLSRGSSSRNSTSSCSIALA TGPWTHRSELSWRCG*ATCSRGGTRLTSRLRAA TPSPGVCRRNGHPLSRRTC*CTPSCLWAF*TARS AQTWSAPSTRSWCSEWPKSLPSPTWLR*FRKVS SYSWSQSWSSPTASTDSSRPPHSLGASCHPGHQ RSLMPPSR*RATSTAWRARTASTPRCLGPRPAPW SCASLSSSHRPNTQPSPSPTSVRRARLATPSSH GWALAPWTPMAPTQPTTWTRWGKTVSGRQMNTW RRPWSTCARYSGSAKRSSGSSHSPWAPPRMRMEK SNSPTASWVRTDSSLRPWGGTRSSMGCEGLKLS TRGTRSCSPSGAMRSPAWSAHSLGCRLPSTTDL QDRWRLCVPGMTSSAASVATTSQNLGWPAGTC*A LWGGGRWPATPAAPGSACASWAVTGRWSRCCWP SSWPLCSASGPSHARCCSPWAMSSTPLP*HC*P SGGSCTSPEGVSCLQSRLEGFATQPHPWAERTWE APPGGNTVILGLLERGSCSRRGIWRKRNQERKA GGPQQRSSCQGSTATLCDSAELSGGLSLPPPRT HGQASSRGLFSTAHLATLLHQAWEPACQQPPGPG LPTGWP*GWQSGLWRFLSLCGTRTVA*VSTPGK NQSF*SCEKTREWLS*FFTVRGVLHVLPAVPRL GRRIPCFRSLRPSQSPGASPQTPSH*AHHPKQWP TSRTPVPCHRWVLVLRRWGHCWVDGVGFCQFLL CSQRWSEALSLQ*HQVLKDMATVQWYLSIQNIQ LQIL*QKPARGLHLHSPHRRHARENSISVVISKP SLCFRCGVLGVCFNVFEIVNVGLCILM*TEHNG ILGPVTKNEACNDHGSE*TCPCF*

Frame 1

PQQGPVHPYWGPWSELGPESVRVLHILLCLEPH HSEATSCVPPRPYFRLCLFHPGGQVPVMVPAHR RQCAPTTLLQPRGDQPLTTSQDTSHTLCFLWPPP H*PPKATHLSSDVCECRPRLPRDLEVRNSAPGF C*NVASSLFLGDVSKNAVPSCQAGGSALPTQCL QRPLQPRPTQPPGPPRLPRVVHAY*GACVGGAPA AEAPARLCQQPEARAGLTLRPLPRHQPPGGVQT NGAEPPGGAQCSPPAEPTLTDGSPGVICEQGLL TGQAAGDPPHPLQGCCPEVRPAETLPLLAALLWP LAPGRIVQSCPGDVAELPAAVAVRA*QAGSGQR LPAPVCVGEMGTLCPGEPADVHQVVCGLSEPRA PHRPGQPQARAHGVPSGQSLCPAQPG*DDSER*A AIPGARAGHPPPPAPTLHGPHIHWELPVTLATS GH*CLLQGEEPRLQPGGPGLQVHPDVWARGPHP GPAPRSAHHTGQTHSQVHLRPVCGEPGWPLLPLM AGL*LHGHQWLLHSQRPGRDGARQCPEDR*IPG EGPGVPAPDIPAQRSAAQAVHTRLGHHPG*EWK KATPRLHRG*GRTHPYAPGAVPDHQWAAKV*N*V PGGPGAAAHPEL*DRQLGPHTL*AVVCHQPQIC RTDGGSVFPG*LPRQLLSLPPHRTWAGQQAPAE PCGAEAGGRPHPRPQAQPALPGQLPDAGLAAAGL LRGLSVLRRAPPMHAAAHPGLCPLRLCHDTADR AGEAAPALKVSAAFRAGWRDLPHSPTLGLRGPG KPLQEGTRSSSGFWSGVPAAAEASGGNATKKGRQ VGPSKGVAARAQQLRSVTAQSSAAAFPSLRQGL TAKPALGAFFPLPIWLLCCTKLGSQPANSHLGL ASPLAGLEVGRVGCGASSLCVGPGQWLKSPLQER IKVSRVVRKPESGCPDSSL*GAFFMFSQLFQDW AVEFHVSGA*DPPRAQGLHRRPQAIEHITQSSG QHRGPLCLVTDGCWSSGVGDTAGSMGSDSASFCS AAKDGQKHCHFSNIKCSKTWQPFSGT*VFKIYN YRFSDRNQHGVFTFIHPTGDMRGRTASQW*FPN QAFVFGVGFWGFALMFLKL*MLGFVF*CKLSIMA F*GL*PKMKLVTTMDLNKHVLAS

Frame 2

HNKVQFTPTGGLGLNLALNPFEYYIFFFALSLI TQKPLPVSLHVRTSDCAYFILVDRYLSWFLPTE GSVPPPLSSSPGGTSPSPPPRTPAIPFASYGLH HTSLLKRHISHQTSVNADPASHEIWRSETLLQVF VEMWLHHYSLEMYQKMQSPHAKLEVLHYRLSVS SALYSPAQPSLQALHAYQESFTPTEEHVLVVRL LLKHLHAFANSLKPEQASPSAHSHATSPLEEFKR MGLNLPEVPSALPRRSQPSLMGALGSSVSRASL LGKQQVTLPIPCRAAVPRFVQQKLYLFLQHCFG HWPLDASFRAVLEMWLSYLQPWRYAPDKQAPGSD SQPRCVSEKWAPFVQENLLMYTKLFVGFLNRAL RTDLVSPKHALMVFRVAKVFAQPNLAEMIQKGE QLFLEPELVIPHRQHRLFTAPTFTGSFLSPWPPA VTDASFKVKSHVYSLEGQDCKYTPMFGPEARTL VLRLAQLITQAKHTAKSISDQCAESPAGHSFLS WLGFSSMDTNGSYTANDLDEMGQDSVRKTDEYLE KALEYLRQIFRLSEAQLRQFTLALGTTQDENGK KQLPDCIVGEDGLILTPLGRYQIINGLRRFEIE YQGDPELQPIRSYEIASLVRTLFRLSSAINHRFA GQMAALCSRDDFLGSFCRYHLTEPGLASRHLLS PVGRRQVAGHTRGPRLSLRFLGSYRTLVSLLLA FFVASLFCVGPLPCTLLLTLGYVLYASAMTLLTE RGKLHQP*RCQLPSEQAGGICHTAPPLG*EDLG SPSRREHGHPRASGAGFLQPQRHLEETQPRKEG RWAPAKE*LPGLNSYAL*QRRAQRRPFPPSAKDS RPSQLSGPFFHCPFGYSAAPSLGASLPTATWAW PPHWLALRLAEWVVALPLSVWDQDSGLSLHSRK ESKFLEL*ENQRVAVLILHCEGRSSCSPSCSKTG P*NSMFQEPKTLPEPRGFTADPKPLSTSPKAVA NIADPCALSQMGAGPQALGTLLGRWGRILPVSA LQPKMVRSIVTSVTSSAQRHGNRSVVLKYSKYTT TDSLTETSTGSSPSFTPQATCEGEQHLSGDFQT KPLFSVWGFGGLL*CF*NCKCWALYFDVN*A*W HFRACDQK*SL*RPWI*INMSLLL