Sequences - Rnomics 📊 Palace

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        Rnomics 📊 Palace
    
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Sequences

Sequence NM_018212

GGGTTCCTCGCGGCGATCCCGACTCTCCTCCCGCGGCTGCAGCAGCTGCCGGTTGCACACGGCCTCGGCGGCGGCGCGGCGAGCGCGGGCCTGTGGAGCG GCGGCCGGGCGCGCGGCCCCGGCGGGCACCCCTCAGAGGGCGGCCGAGGAAGCTCCGGGAGGAGGAGCAGGACCACGAGGAGGTGGGAGGCGGCGGCCGC CTGGGGACCAGCTCCGCGCCTCGGCCTCTCCGCCCCCTCCCCAGCCTTTCTCTCGCCCTCTTCTCCCACACTCCCGGCCGGCGCCTCGGCTTTGTGCGAG GAGATGGTGTAGCCCCCTGGCCGCCGAAGGAGGAGCCGGACACTTGTCTCCCGTCTCCGAGCTGCTCCCCACCCCTGGAGGAGAGACCCCCCCCTCGGCT CGGCGCCTTCTGCGTCTCCCGGCTGGTGGGGAAGCCTCTGCGCCGCCGGCACCATGAGTGAACAGAGTATCTGTCAGGCAAGAGCTGCTGTGATGGTTTA TGATGATGCCAATAAGAAGTGGGTGCCAGCTGGTGGCTCAACTGGATTCAGCAGAGTTCATATCTATCACCATACAGGCAACAACACATTCAGAGTGGTG GGCAGGAAGATTCAGGACCATCAGGTCGTGATAAACTGTGCCATTCCTAAAGGGTTGAAGTACAATCAAGCTACACAGACCTTCCACCAGTGGCGAGATG CTAGACAGGTGTATGGTCTCAACTTTGGCAGCAAAGAGGATGCCAATGTCTTCGCAAGTGCCATGATGCATGCCTTAGAAGTGTTAAATTCACAGGAAAC AGGGCCAACATTGCCTAGACAAAACTCACAACTACCTGCTCAAGTTCAAAATGGCCCATCCCAAGAAGAATTGGAAATTCAAAGAAGACAACTACAAGAA CAGCAACGGCAAAAGGAGCTGGAGCGGGAAAGGCTGGAGCGAGAAAGAATGGAAAGAGAAAGGTTGGAGAGAGAGAGGTTAGAAAGGGAAAGGCTGGAGA GGGAGCGACTGGAACAAGAACAGCTGGAGAGAGAGAGACAAGAACGGGAACGGCAGGAACGCCTGGAGCGGCAGGAACGCCTGGAGCGGCAGGAACGCCT GGAGCGGCAGGAACGCCTGGATCGGGAGAGGCAAGAAAGACAAGAACGAGAGAGGCTGGAGAGACTGGAACGGGAGAGGCAAGAAAGGGAGCGACAAGAG CAGTTAGAAAGGGAACAGCTGGAATGGGAGAGAGAGCGCAGAATATCAAGTGCTGCTGCCCCTGCCTCTGTTGAGACTCCTCTAAACTCTGTGCTGGGAG ACTCTTCTGCTTCTGAGCCAGGCTTGCAGGCAGCCTCTCAGCCGGCCGAGACTCCATCCCAACAGGGCATTGTCTTGGGACCACTTGCACCTCCACCTCC TCCACCACTCCCACCAGGGCCTGCACAGGCTTCAGTAGCCCTCCCTCCTCCCCCAGGGCCCCCTCCACCTCCTCCACTCCCATCCACCGGGCCTCCACCG CCCCCTCCTCCCCCTCCTCTCCCTAATCAAGTACCCCCTCCTCCTCCACCACCTCCTGCCCCACCCCTCCCTGCATCTGGATTCTTTTTGGCATCCATGT CAGAAGACAATCGCCCTTTAACTGGACTTGCAGCTGCAATTGCCGGAGCAAAACTTAGGAAAGTGTCACGGATGGAGGATACCTCTTTCCCAAGTGGAGG GAATGCTATTGGTGTGAACTCCGCCTCATCTAAAACAGATACAGGCCGTGGAAATGGACCCCTTCCTTTAGGGGGTAGTGGTTTAATGGAAGAAATGAGT GCCCTGCTGGCCAGGAGGAGAAGAATTGCTGAAAAGGGATCAACAATAGAAACAGAACAAAAAGAGGACAAAGGTGAAGATTCAGAGCCTGTAACTTCTA AGGCCTCTTCAACAAGTACACCTGAACCAACAAGAAAACCTTGGGAAAGAACAAATACAATGAATGGCAGCAAGTCACCTGTTATCTCCAGACCAAAATC CACACCCTTATCACAGCCCAGTGCCAATGGAGTCCAGACGGAAGGACTTGACTATGACAGGCTGAAGCAGGACATTTTAGATGAAATGAGAAAAGAATTA ACAAAGCTAAAAGAAGAGCTCATTGATGCAATCAGGCAGGAACTGAGCAAGTCAAATACTGCATAGAGGAACAGACTAAGGAGAGATAGGACTTTAATCT GGAGGAAAAATATCCTACAAACAACAACTGTTCACAACAGCAAACCCCTACATTTATGAGCTGTAAGAAGAAAATGGAGACAAACAGAAGGAGGGAAAAA CCAACCTACTCTGAAAGCCTTCAGACATTATGACTCTGGTGATAAGCTCTTTCCCTCTCCGTTTGCTGCTTTTTTCTGGCCTTTACAACAGAATGGAAGA GAATCATTTAAGAGTTCCTGTAACAGTTATGCAGAAAATACTAAAACCCATCAGGCAAGATCACCACGCATTGAAATATTTTCATATCAAGATAAAGTCG CACATTTTCCACAATACATTGCTAAAATAAAGAGGAGAAAGGCTTAGGAAGTTTTTTTGCAGAGAGTGCTGGTAAAGAATTGAGCAAGTTTGCTATTGTA TTGTAATGTTTCTCTCAGGTTTGTTCTTCCTATCATGTTTGATATTCCATGAATAATTGAGATCAGCCCTATGTAAGTTAAGATCATAATATGTGGAACA AATGGAATTGTAAGTGCTTTCAAAGGGTAATATTTATAAGAAAGTGTCCGAAAAATGTTTCTTCAGCTTGAGAAATTTTAGAATGATAGGAAGTTTCTCG AGTTAGCCTTCATGCAATTTTGTAGATTAAAACATAAAATTTGTCCAGAACTTAAAGATTTAGATGCCTTCCTAAATTGTTACAATGCTTTACCAAATCT ATGACTTCTACATAACACAAACCAGTGGTCAAATGTAAACACTATATTGTAGATTTACTGTAGGTTTTCAACCTTTTTTAGATTTATGCATGTGGACATT TTTATAATGTAATTACAATCACCACAAGGTTAGCTTTTTTAATTGCAGACAGTAATGCATGTCACACTAATATGTAGTGGCCTTTTCAAGGCCTAGTCCC AGGGAAAACATTTTGTAGAGTATAGGGGAGTGGGAGGAAGGGGAGGAATAATTTTTTATTTAAAGTTGATTTCTGCACTATCTTTTTCTCAGTTACCTGC ATGAATAAATAATGAGAAATATTTTGTGACTTTAATTGGTAAATATGTTACAAAACCAAGTACTTAATCTTTTACATCATGTCTTCAGCTATTTGTATTT TAACCAGTAATTTCAATGGTCTGAAACATGATTCTGAGCTTCACATAATATCTTAACTGTGGAACTCAAAAGTTTGATCACTGAATTTGGCAGTTATTAT TACCTAGGTACCCCCGCTGTTACACAGGTGTTTAGATACGTGTTCCTGAATGAAGCTGCTTTTGAATTTTGTTATGTTGAAATGCAAGAAATAACAATGA TGGCAGCAATTAAGGTCACAGAAATCATTAGGTAAAGGAAAACCAATGAGGAGTTCTGCAGTTTTCTTTTAATAAGTAAAGTGAGACTTGGGTGGTGGGA AGAAGGAAGGTGGGAAGAAGGAATTAGACACTCTGCCTGCCACTCTGCGTGTGTGTGCTCTCGCGCACGTGCTGTCTATATGGAAGCCACTCCCTTTTCT TTCCTTTGAAACTGGTAAGGTTAAAATAGGGGAGAAATCCTACATGTTGGAATGATAGCTTTTTGGAAAATTTAAGAAACTCTCCAGGCTCTCCATCTTG ATTTATGCTTGAGTTGTTATGTGCCATATTTGCTTTGAACTCTGATTATCAGAAGTTTTACTAAAACTTTGAAATAATTCACTTTCATCTGCTTTCTAGA TTTTGTACATCTCAGTCCATAAAGCAAAGCTTGTTGATAGTGTAGTTTTCTAAACGCTGCAAATTTGCAGCCTTTACCACTACAAAGAAGTTTGGATGAG GGATTTTTTTTTTCTTTGTCAAAATAGTTCCTGTTTCTGTAGAAATTTCATTTTTAGATTAAACTGTGATGGATGAGCTATCATAATTCAAGTATACATT TCTTTTTTCTATCAGATATTCATTGTCATGCAGTAGTAGTAAAAACATCAAAGATGCAGCAAGCTTATTAAGTATTATTTTCTAAAAGAAATAGGAGGCA TTTTCATCTTTATTATTGTACTTTTGGTTATGCAAACACTTTGATAATATAAACAGTTATGTCCCCTATAAATCTGGTCAGCAACCTCTTTTGATTTTGT TGGGTAAGTTAAATAGTCTGTAGTAGGTAGAGTACTGGGTACAAGTGGTCCAAACTAAGATAAGAGACTAAAATAAAATGCTAAATCTTAAAAGAAACTG GGTTTATGCACTAAACGTTTTGTGCCTTGGTCTAATATTAACATGATGTATGTGTAAACTGACAAAAAAAAAAAAAAAAAAAAACCAGTGTTGAATCATG CTATATTTCCCATCATCCCAGATTGCTAAATGTTCTTTCCAAGAAGTCTGAATGAATTATTATATACATTTGCTATCATACATGACAGTTGTGTCATTAT TAGAGATTTCAGTAATTAAAATGGGAAACAGAAGCCTAAGTTATTTACCTTATCAAAACCACGTTCCTTGGAACCACATTATTATGATGGTTTTTGTGCT CTTGTACGTTGGATGTCTTAAGCTGAGTACAGTTTAGGGGATCCTTTCTAATGACAGGAAGGCACTGCTTTCCTCAACACTGTGATCTGACCTGTGACAA GTCTGTACTATCCACTATGTAAATGGCTCACAAGTCAATTGCAAACAAACTGAATGTACAAATCTTAGTGCTGGTGCTGAAATCTCTTCAGAATAGTCAT CATGATTTAAAAGTTTGTTTAAAAATTTGCAAGCATCAAGTGTCAATCAAAACTGAAGATGAAACACTAATGAATGTTGAATTCTCATGCTTTTAGGTGT ACTTCCTTTTTAGAATTTTCAGTTTTCTGCTATTTTTACCGTAACTATTTCGTTTAAATTTGTTTCATTTAAGTTTCCTACACGCTAACTTCGTTTGTGC GATTGAAATAAAATTGCAGTATATATATGTTGCTTGTTTGTGACACTTAGATAATCTTCTGAAATAATTTGTTTTAAAGTAAGTTATATTGGATGTGAAA AACACCTTTTAAAGTCCAAGACTTTACTACTTAAAAGTTTACATGTCACGTCACTATTCTTTACAGATTTCATAGAAGTCGTGAATACTAAGTAATGTAT ACAAAAGAAATATGTGATGATGTGTCTACTTTTTGTTTGAAATAACTGTTGGGTGTTCCCTCTTCTTATTTTCTCTCTGCCCACCTTGACACAGTAACTT CCTCTTATAGTCAAGATGATGATTAAGTGTTTAATTTTTATTCCATTTTGTTCTGCAACACGTTCAGGTACTTAAAACTCATTCATGCAGTTAGAATTAT CCTTTATGTAGTTTGCATGGTAAAGGACATTGTGTGGTAAAGGGCATTATTGAGTAATGAATTTTAAGTATAGCAAAATATGTATAGTGTTTATACATGA TGCTGATTTCTTAAAACCTACATATAAGCAGTAGTACTTTTTCTCTATTATAAAGTATTAATTTTGAGTTCCATTTTATAATTCTGATGTCTTCATTAGA AATACAAAAATACAATCCTTGTATTTTTTCTTTGACCAGACCCAAATTTTCCCCTTCCCCCCTCCATTCTCCTCTCCACTTCTCGTGGACCGCGTGTTCC CAATATTCATTAACATTTGCAGCCATTACAGAGTTACAGTTGTAAAATTTTCAGCTGTTTTTTTTTTTTTTTTTTTGCTCTAGCCTGTCTCATGTTCTTG CTTCTCTTCATATGTAAGTCAGTATTTTTGTCTACAAATTAAAAGTCACTTGTCATTCAAAAATGAGTTAAGTAACATGATAATCTTTTAAATTTACCTA GCTACAACTTTTATGTCTCTTGTAAATTTATATATACTTTCAGTGCCATTGTGAAGAATTGGCCTTTTAATTCTAAGTAGTATTACCCTATGAAGCACAG TGTGCAAAGGTATGCTACAAGGTCTCTTTAATTCCTGTGTGGCCATTATAATTTTATAACACCATTACCCTTTAAATTCTACCGATTATAAGCAGCGTAA AAGTAACTATATAAAGCAAACATCGCAAAGGAACTCTGCAGGAGCTCTTAATTCCTTTATGTAGCTATCATAAAATTCACTTTCCTGAAGACATTTACTC TCATTCACTTCCAAACTCCAAACCTTTTTCTGGTAGCACCACTTTTGTTTTTAATAGAAAGATGAGTTCATATCTGTACATCTCTCCAAAGCTCTAAGGA ATGAGAAAAGGATCCTAGTATATTGAAATTACTGATGTTTAATACCTCTGCCTTTTCACTAAAAGCCATTTAATATTTTTAAAGTCAAAACTTGACATAC AGGTATTTATAAGGAATCTCCATGACTCTGAAGGAATGAAATTGATGTAGGTAGCTTTGGCTATGTAAAGACATAGTAGAGGACAATTACTTAAAGAAGA GTTTTCTTTTGAGGATTTGTAGATTTGACTAAGCAGCTGAAGTCAGTAACCCCTCAAGAAAGTCCGTTTATAGAAGCCAAGAACTGTTGGAGGTCTGTGA TGCAGGTTTTTCTGTTCCCAACATCAAAAGCTGTGGATTATTTGGTGTGTTCCCCTTTATGTTATCTCTCGATAATTTTTGAGACATCAAGATTTTTTAA AATATCAATACTGGAAAGATGAAACCTTCAAATTAAAACCTAAAATTGATTAGAAAGAAAAGTAAAATATTAATGCAGTAAATTTAGGATGGTTACAGAT ACTCACCATCAACATAAATAAATGGAGTTCTAGGATAAATTATTTGTGGAATACTAATGGTCAAGTCACATAAGAGTAAAATCTTTTGGTGAGGAGACAC ATTTGACAACTGCTAAAGAATTAACTAAATTTGTCTTTCTAAATAGTTTTCTTTATAAAGTAACAGAAACATTGTAAAAGGATAAATGACTGTCATAATG ACTTAGGATGTTGTAAGAATGTCTGCCACATTTATTGGTTATTTCTGTTGAAATCTGAAGGAATCGATACATCTGAAAATTGAGAAAGGGAAATAGGACT GTCCCCGTTACAGATACTCTGTGATGCACACAACCTTCTAAACGGAAGTGTTAGTATCATTTAAAGCACATAGTAGGCCTTGAGTATTTGCAGATTAACA TGCAGAAAAAATCAAAGATGAAGCCCCAATTAAGTGTTTGAACCAAAGAATCACAGTCACTGAGCTGCACCCCCGTTCTGTGAAGCATGTTAAATACTCA TAAAGAGCAGAGAGCAGGGCCCGTAGACGCTTCTGGTGTAGGACACAGGAATTCTAGGCAGAGGGAGAAAATTAGGGGCCCCAGTTGGTGGCTGAGAGTA AAAAGAATATACCATTTGAGTAGTGCTGTTCTTTTTCCTCAGTTTTTAAAGACATATAATTCCTAGTAGTTAGGACATCTAAATAGCTCGGTAAACTGGT CAGAGGCGGGAGGATTGCTTGAGGCCAGAAGTTTTGAGATCAGCCTGGGTAACAGGGAGACTCATTTCTACAAAAAAATTTAAAAATTTAGGCCAGGCAT GGTGGTGCACACCTGTAATCCCAGCTACTCAGGAGACTGAAGCGGGAGGATCACCTGAGCCCAGGGAGGACGCGGCTGCAGTGAGCCGTTATCATGCCAC TGTACTCCAGCCTGGGTGACAGAGCGAGAACCTGTCTCTAAAAAAAAAAAAAAAAAATTCTAAGAGAATATAGCTTTTCATAGAAATTATTAGAAAAGCT TACATATTTCATTAGAGAGCCCAGTTTGTTAGACTACATTTATTCCGTAAAAGTTCTATATACAAATGACAACCCATAGTTTATCATGTAAATCTGATTT AACTGTTCCCTTCAATTCCAAGAAAGATTTCTTCAGCAGTAGATGACAATTCTAAAAGCATAAAGAAATAACTAATAAAGGAGATGGATGATGTTATAGG TTGGTTTGGTTGGGTTTTAGTAAATAGTTATTCTTCTAAGAAGGCTTAGAAAATCGAGAATTGAATAGTTGGTACTTTGAATTCCATAGGAAAAAGCACT CAGAAGAAAAAGTCTACATTGGCTAGTGTTTAGATTGAGAGTTAATTTTCCCATCAAGTCCAAAAGTTTCCATCCAAGTCTATAGAAACTGAGAGAAAAG GTTCTTGGCTTACACTTAAAATACACATTGTTGCAACCATATAAGAGAGATACATTACAGAACGCTTTTAAAAATTTGGTCTCTTAAGCGCCTAACAGTC CATGCTTTAGTCACATCTGTGAAACCTCTTTTCTTTTTTTCTTTTTCTTTTATTTTTTTTTTTAAAGATTAAAGGCATTTTAAAAATAAATGTTTCATGG CCGGGCATGGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCTGAGGTGGGCAGATCACCTGAGGTCAGGAGTTTGAGACCAGCCTGGCCAACATGA TGAAACCCCATCTCTACTAAAAATACAAAAAAATTGGCTGGGCATAGTGGTGGGCACCTGTAATCCCAGCTCTTCGGGAGGCTGAGACAGAAGAGTCGCT TGAATCCAGGAGGTGGAGGTTGCAGTGAGCTAAGACCGCGCCACTGTACTCCAGCCTGGGCGACAGAGCGAGATTCCATCTCTAAATAAATAAATGTTTT TCAACGTGTTTTATGTGAGAAATACCAGCTTTTCATTATTACTACCAGTTGATCTCAGGTGTCACTTGGTTGGTTCTGCTGACCGAGGCACTGGGCATTT TAAATATGGAGTTTCCCTCCACCCATTGATCAAGTCTGAGGTTTGTCCATCCTTGGTGGCAGGCTAGCTTAACCATGGATTCACAAACCCCATTTGATTG TCGTAAGTCATAAGGCCACCCCAGTGCCAGTGGTTGGGCATCACAGTGAGTCTGAGGTGATGAATTTGAGTTAGCTGTAGGCTAGTTCCGCAACTCAGCA ATAGCCCATGGATGGTTGGTAAAAGACGTTGACTTTGCCACTTAAATTTCCAGGAGAAGAATAGCTTATAGTTTATCTGAGGAAAGTAATTGGGAAGGCT TAGATATTGAGAAGAAAGCCCTGTTAAAATCTAGGTAGCATTTCCTTTCTTCTTTATTACTAGAGGGATGGGAGGTTCAGGCCTGAGTCAGGACTTTACA ATTTGGTGTCCTTCCCAGAGGTACTTTGGGCTTGATCATTTTAAGTTTCAATTGCAAAAAAAAATTTTTGACGGAGTGTTGCTCTGTCACTCAGGTTGGA GTGCAGTGGTGCGATCTCGGCTCACTGCAACTTCCCCCCCCTGGGTTCAAAGGGATTTTCCTGCCTCAGCCTCCCAAGTAGCTGGGACTACAGGCGCGTG CCACCATGCCCGACTAATTTTTGTATTTTTAGTAGAGATGGGGTTTCACCATGTTGCCCAGGCTGGTCTTGAACTCCTGAGCTCAGGTGATCTGCCCGCC TCGGCCTTCAATTGCAGAAGTTTTTGAAGGGAGAATATTTGATCCTCACATAAAATGTCCTTGTTTCTGAAAGAAAACATGGTAAAAATTGTTATTGAGT CCATGTCTTTGCCACCTTGTTGGACTTGATTTCCCTTTCTCTGTGTTCCTCCCGCCCTCAGTCTCTCTCAGTCTGTCCTTTTTTGTGTGTGGAGTTGTGG GCAGGTCATTGGACTGGGACTGACTTTACCAGTTTTCAGGCTGTGGGGCTAGTCAGTCATTCTCTCTGAGCCTTCTACCTCTAAAGTTGAGTTCTTTTTT TAAATTCTTTTTGTTTTGTTTTTATTTTTTCCTTGCCACTATACAAGCAAGGATAGATAAAGCTTTTTATTATTATTGTTATTATTATTATTTCGAGACA GTCTCGCTCTGTCATCCAGGCTGGAGTGCAGTGGTGTGATTTCAGCTCACTGCAACCTCTGCCTCCCGGGTTCAAGCGATTCTCCTACCTCAGCCTCCTT AGTAGCTGGGACTACAGGCATGCGCCACCACACCCGGCTAATTTTTGTATTTTTAGTAGAGACAGGGTTTCACCGTATTGGCCAGGCTGGTCTCGAACTC CTGACCTCAGGTGATCCACCCACCTTGGCCTCCCAAAGTGTTGGGATTACAGGCATAAGCGACCGTGCCCATCCCCGATAAAGTTGAGTTCTGAATTTCC TCTTTCACTGTATTCTCGGCAGCTACTGGTTGGTTTATTCTTTTTTTTTAATCTTTTTTGGTTTATTCTTCTTTTGATCTTTGAAGAGAAGGAGAAAAAA GATCTGAGTTTGGCTCTCCCATCTTAAGTGCAGCTTTTAGTTGTTTTATAGTCATAGACGCTATTGCACTGGACAGCATGCATCCTGGATGTAAACAATG CGGAAAAATCAATGGAGTGACCATCTTGGGGTCAGTGGTGTTGCATAAAGCACCAGTGGTGTGCTGTTCTGTGTCAGTTTCCTCTGCGCCACGTGCTTTC ACAGTTTGAATTACCAGCATCTCTGTGGTGGCTTCAGTACATTCTCCATTGTGCTTCAACCTGGAAGCACATTCTGCCGTTCAGAAAGACTGATTCCAAT CATGTAATGGGACCACACGAGATCCATGCTCCAATTATATGAATAGCAGAAGGTCCATTTGACTCTTGTAGTTCAAGAGCTGTTTCTAAGTAAACAGACT TTCCAGAGCTCGATGAAGTGAAGAAGCCCTTCTTTCAATTCCTGGGCAGAATTCAGTGGTTTTCATATCATCTGAACCTGCTGTGCTGCTGTTTATTCTA TCACTGTCAGCCTTGAAAGGAAAAAAGGAATAATCTTACCCTCCTGCCCTTCTTATTTTATATCTTCCATCTTATCCATCTATATCCATGTAGTCATTCC TTCCGAGTTCCCTGGTTTTAATCCAAAAGACTCTGTTTAACAGCAATGTCTTGGCAGACCAGGTGCCGCTTCCGTGCCATTTGAGGGCTCTGAGTCTTTG CTTCGTCTTAGGAAGATAAAGATAATTTGGCAGAAAGTCAGAGATGGAAATAGCAGTTTGGGATGATAAAAGATGGGTCCTGTTTTGCTGACATTCTTTT ACTTTGGTTCTTGGTGCGTGTCCTTTGGGATTCATTTCTTGCTAGCATGAATAGGACATGCTTTTCGTTAGGTGCTTTTCTTTTTTGGAGAACATGAAGT GTTTCTAACAAAACTGAATGAGCTAGAAAGAATTCTATTTTGAGACATCTGTAGTTGATGCAAAGTATTTCTGTAATCCTCAATGACAGTACTTACATAT TTGCATAGAATTTTTTTTTTAATTTTTGAGGAAACCTCTCTGGAGTCTGTATTTATAGGAGCATCCTGAAAGTCCCTATTATGTAGCTGGTGGGAGCGAG AGAGGGACAGCCACACTCGTGCTGTGAGCAGAGCACAACTTCAGGCAGAGTGAATGCCTTCTGAGTTCTCATTGGAAGCTTTCTGTTGCTCAGCCTCTGG CAGATTTCAGAACCTTCTACTTAAGCCAGGTGTGGTGGTGCGTGCTCCTAGGCACAGCGACTCGGGGGGCTGAGGCAGAAGGATCACTTGAGCCCAAAGT TGGAGGCCAGCCTGGGCAACATAGCGAGGCCTGTCTCCTTAAAAAATAAATAAATAAATAATAAATAAATAAATAAATAAAAACCTTGTCCTTGACTATT GTGCTGTCTGCTGCCCCTTTGTAGGGATGGGGTTGGGGTCAGAATAAGCATGTGCATGAATGGCGGAAAGCTTTGGTGGTGTTTGTTTGTTTGTTTGTTT TTTGAGAGGTGGGGGAGTCAGCAGTGAACCTTTCTGGTTAAAGAACAACGTACATAATTTCTATTATGAGATTTAGAAGGTTAAATACTTTTTTTTTTCA GGCCTACCAAGTTGATAGACCAAAAGTATATAGTAGAACAGCACAGTAGAAAAAATTTAAAAGTGAATTTCTTATGGTCCAAAAGGATGGATAGTCACAG TCCATAACCTTTCATAATATATGCTGGAATTGGAATCTCTTGTCATCTTGCTTTGCTCTGAATTTTAGAACTAGAAGTGTGCATGTATGTCAAAAGATTA TGCAGAGCTATTTTCTTTGCTAACAATGTAAACATTTGCACCCCATGAATGGGACTTTATAATCTGGAAGTGAGCCTAAGGTTGCGTATACTGAAGTCAT GTTTTAAAAGTTAAGGTTGACTTAAACATATACAAGGCTGTATTTTAATTGTAACTAGAAATCATTTACTATGCATACAGAACCTCATGTATCTTATCAT GGAATTTGTGAATTAATGGGCCTTGCCGAATTCAAGGGTAAGGGAAACTGGTAACAACTTGTTTTAAATCAACATACTATAAGCTCCTGCTTGCTTGACT CAAGTTGTTTGAAAATCTGAATTAAACAGGATCTCATTGTCAGGAAACATCTTCTAAGCTTGACATCTACGTTTAAGAAGGGAACGTGGAAGAGAAGGTG AGACATGAAACTAAAACAGCTGGGAGGGTAGGATCAGACTGCACCTGATTTTTGGACCAAAGTTTCATATAGGAATAAATAAAAAGGAGGACCACTTGTG AGCCAACCTAGGAAGGACTTGCCAGAAAGTAGCAGCTCCTGCTGCAAAATACAGTGCCTTCAAAATGATTCTCTGTGTGAATTGCATGCAATTTCATGTA ACCATAAAGTGTAACCTGTATGTGCATGACATGTGTCTAGAATGTGTAAAGTTAGGATTCAGCAGGAAGGGGCCTGGCCCTGTCACTGTGGTGGATCAGT GGACCTGCTGAAGTCACTGGACTCATGTGACTTAGGTTTGCAGCATCAGACCCCTGTGTTTGCATTAAGTGGCCACATCGTTGAAATCGGATCAATCTCT CCCTCAGCTTTCTTTCCTACTTTGCAGCTTTGCTGGTTTTAACTGCTTCATTCTTCTGCTTCTTGGTATCCTTTTTTCTTTTGAAATAAAAACATGAAAT ACTTAATTC

refseq_ENAH.F1 (forward primer)
refseq_ENAH.R1 (reverse primer)
Single exon skipping

Frame 0

GFLAAIPTLLPRLQQLPVAHGLGGGAASAGLWS GGRARGPGGHPSEGGRGSSGRRSRTTRRWEAAAA WGPAPRLGLSAPSPAFLSPSSPTLPAGASALCE EMV*PPGRRRRSRTLVSRLRAAPHPWRRDPPLG SAPSASPGWWGSLCAAGTMSEQSICQARAAVMVY DDANKKWVPAGGSTGFSRVHIYHHTGNNTFRVV GRKIQDHQVVINCAIPKGLKYNQATQTFHQWRD ARQVYGLNFGSKEDANVFASAMMHALEVLNSQET GPTLPRQNSQLPAQVQNGPSQEELEIQRRQLQE QQRQKELERERLERERMERERLERERLERERLE RERLEQEQLERERQERERQERLERQERLERQERL ERQERLDRERQERQERERLERLERERQERERQE QLEREQLEWERERRISSAAAPASVETPLNSVLG DSSASEPGLQAASQPAETPSQQGIVLGPLAPPPP PPLPPGPAQASVALPPPPGPPPPPPLPSTGPPP PPPPPPLPNQVPPPPPPPPAPPLPASGFFLASM SEDNRPLTGLAAAIAGAKLRKVSRMEDTSFPSGG NAIGVNSASSKTDTGRGNGPLPLGGSGLMEEMS ALLARRRRIAEKGSTIETEQKEDKGEDSEPVTS KASSTSTPEPTRKPWERTNTMNGSKSPVISRPKS TPLSQPSANGVQTEGLDYDRLKQDILDEMRKEL TKLKEELIDAIRQELSKSNTA*RNRLRRDRTLI WRKNILQTTTVHNSKPLHL*AVRRKWRQTEGGKN QPTLKAFRHYDSGDKLFPSPFAAFFWPLQQNGR ESFKSSCNSYAENTKTHQARSPRIEIFSYQDKV AHFPQYIAKIKRRKA*EVFLQRVLVKN*ASLLLY CNVSLRFVLPIMFDIP*IIEISPM*VKIIICGT NGIVSAFKG*YL*ESVRKMFLQLEKF*NDRKFL ELAFMQFCRLKHKICPELKDLDAFLNCYNALPNL *LLHNTNQWSNVNTIL*IYCRFSTFFRFMHVDI FIM*LQSPQG*LF*LQTVMHVTLICSGLFKA*S QGKHFVEYRGVGGRGGIIFYLKLISALSFSQLPA *INNEKYFVTLIGKYVTKPST*SFTSCLQLFVF *PVISMV*NMILSFT*YLNCGTQKFDH*IWQLL LPRYPRCYTGV*IRVPE*SCF*ILLC*NARNNND GSN*GHRNH*VKENQ*GVLQFSFNK*SETWVVG RRKVGRRN*TLCLPLCVCVLSRTCCLYGSHSLF FPLKLVRLK*GRNPTCWNDSFLENLRNSPGSPS* FMLELLCAIFALNSDYQKFY*NFEIIHFHLLSR FCTSQSIKQSLLIV*FSKRCKFAAFTTTKKFG* GIFFFFVKIVPVSVEISFLD*TVMDELS*FKYTF LFSIRYSLSCSSSKNIKDAASLLSIIF*KK*EA FSSLLLYFWLCKHFDNINSYVPYKSGQQPLLIL LGKLNSL**VEYWVQVVQTKIRD*NKMLNLKRNW VYALNVLCLGLILT*CMCKLTKKKKKKNQC*IM LYFPSSQIAKCSFQEV*MNYYIHLLSYMTVVSL LEISVIKMGNRSLSYLPYQNHVPWNHIIMMVFVL LYVGCLKLSTV*GILSNDRKALLSSTL*SDL*Q VCTIHYVNGSQVNCKQTECTNLSAGAEISSE*S S*FKSLFKNLQASSVNQN*R*NTNEC*ILMLLGV LPF*NFQFSAIFTVTISFKFVSFKFPTR*LRLC D*NKIAVYICCLFVTLR*SSEIICFKVSYIGCE KHLLKSKTLLLKSLHVTSLFFTDFIEVVNTK*CI QKKYVMMCLLFV*NNCWVFPLLIFSLPTLTQ*L PLIVKMMIKCLIFIPFCSATRSGT*NSFMQLEL SFM*FAW*RTLCGKGHY*VMNFKYSKICIVFIHD ADFLKPTYKQ*YFFSIIKY*F*VPFYNSDVFIR NTKIQSLYFFFDQTQIFPFPPPFSSPLLVDRVF PIFINICSHYRVTVVKFSAVFFFFFLL*PVSCSC FSSYVSQYFCLQIKSHLSFKNELSNMIIF*IYL ATTFMSLVNLYILSVPL*RIGLLILSSITL*ST VCKGMLQGLFNSCVAIIIL*HHYPLNSTDYKQRK SNYIKQTSQRNSAGALNSFM*LS*NSLS*RHLL SFTSKLQTFFW*HHFCF**KDEFISVHLSKALR NEKRILVY*NY*CLIPLPFH*KPFNIFKVKT*HT GIYKESP*L*RNEIDVGSFGYVKT**RTIT*RR VFF*GFVDLTKQLKSVTPQESPFIEAKNCWRSV MQVFLFPTSKAVDYLVCSPLCYLSIIFETSRFFK ISILER*NLQIKT*N*LERKVKY*CSKFRMVTD THHQHK*MEF*DKLFVEY*WSSHIRVKSFGEET HLTTAKELTKFVFLNSFLYKVTETL*KDK*LS** LRML*ECLPHLLVISVEI*RNRYI*KLRKGNRT VPVTDTL*CTQPSKRKC*YHLKHIVGLEYLQIN MQKKSKMKPQLSV*TKESQSLSCTPVL*SMLNTH KEQRAGPVDASGVGHRNSRQREKIRGPSWWLRV KRIYHLSSAVLFPQFLKTYNS**LGHLNSSVNW SEAGGLLEARSFEISLGNRETHFYKKI*KFRPGM VVHTCNPSYSGD*SGRIT*AQGGRGCSEPLSCH CTPAWVTEREPVSKKKKKKF*ENIAFHRNY*KS LHISLESPVC*TTFIP*KFYIQMTTHSLSCKSDL TVPFNSKKDFFSSR*QF*KHKEITNKGDG*CYR LVWLGFSK*LFF*EGLENRELNSWYFEFHRKKH SEEKVYIG*CLD*ELIFPSSPKVSIQVYRN*EKR FLAYT*NTHCCNHIREIHYRTLLKIWSLKRLTV HALVTSVKPLFFFSFSFIFFFKD*RHFKNKCFM AGHGGSRL*SQHFGRLRWADHLRSGV*DQPGQHD ETPSLLKIQKNWLGIVVGTCNPSSSGG*DRRVA *IQEVEVAVS*DRATVLQPGRQSEIPSLNK*MF FNVFYVRNTSFSLLLPVDLRCHLVGSADRGTGHF KYGVSLHPLIKSEVCPSLVAG*LNHGFTNPI*L S*VIRPPQCQWLGITVSLR**I*VSCRLVPQLS NSPWMVGKRR*LCHLNFQEKNSL*FI*GK*LGRL RY*EESPVKI*VAFPFFFITRGMGGSGLSQDFT IWCPSQRYFGLDHFKFQLQKKIFDGVLLCHSGW SAVVRSRLTATSPPWVQRDFPASASQVAGTTGAC HHARLIFVFLVEMGFHHVAQAGLELLSSGDLPA SAFNCRSF*RENI*SSHKMSLFLKENMVKIVIE SMSLPPCWT*FPFLCVPPALSLSQSVLFCVWSCG QVIGLGLTLPVFRLWG*SVILSEPSTSKVEFFF *ILFVLFLFFPCHYTSKDR*SFLLLLLLLLFRD SLALSSRLECSGVISAHCNLCLPGSSDSPTSASL VAGTTGMRHHTRLIFVFLVETGFHRIGQAGLEL LTSGDPPTLASQSVGITGISDRAHPR*S*VLNF LFHCILGSYWLVYSFFLIFFGLFFF*SLKRRRKK I*VWLSHLKCSF*LFYSHRRYCTGQHASWM*TM RKNQWSDHLGVSGVA*STSGVLFCVSFLCATCF HSLNYQHLCGGFSTFSIVLQPGSTFCRSERLIPI M*WDHTRSMLQLYE*QKVHLTLVVQELFLSKQT FQSSMK*RSPSFNSWAEFSGFHII*TCCAAVYS ITVSLERKKGIILPSCPSYFISSILSIYIHVVIP SEFPGFNPKDSV*QQCLGRPGAASVPFEGSESL LRLRKIKIIWQKVRDGNSSLG**KMGPVLLTFF YFGSWCVSFGIHFLLA*IGHAFR*VLFFFGEHEV FLTKLNELERILF*DICS*CKVFL*SSMTVLTY LHRIFFLIFEETSLESVFIGAS*KSLLCSWWER ERDSHTRAVSRAQLQAE*MPSEFSLEAFCCSASG RFQNLLLKPGVVVRAPRHSDSGG*GRRIT*AQS WRPAWAT*RGLSP*KINK*IINK*INKNLVLDY CAVCCPFVGMGLGSE*ACA*MAESFGGVCLFVCF LRGGGVSSEPFWLKNNVHNFYYEI*KVKYFFFS GLPS**TKSI**NSTVEKI*K*ISYGPKGWIVT VHNLS*YMLELESLVILLCSEF*N*KCACMSKDY AELFSLLTM*TFAPHEWDFIIWK*A*GCVY*SH VLKVKVDLNIYKAVF*L*LEIIYYAYRTSCILS WNL*INGPCRIQG*GKLVTTCFKSTYYKLLLA*L KLFENLN*TGSHCQETSSKLDIYV*EGNVEEKV RHETKTAGRVGSDCT*FLDQSFI*E*IKRRTTC EPT*EGLARK*QLLLQNTVPSK*FSV*IACNFM* P*SVTCMCMTCV*NV*S*DSAGRGLALSLWWIS GPAEVTGLM*LRFAASDPCVCIKWPHR*NRINL SLSFLSYFAALLVLTASFFCFLVSFFLLK*KHEI LN

Frame 1

GSSRRSRLSSRGCSSCRLHTASAAARRARACGA AAGRAAPAGTPQRAAEEAPGGGAGPRGGGRRRP PGDQLRASASPPPPQPFSRPLLPHSRPAPRLCAR RWCSPLAAEGGAGHLSPVSELLPTPGGETPPSA RRLLRLPAGGEASAPPAP*VNRVSVRQELL*WF MMMPIRSGCQLVAQLDSAEFISITIQATTHSEWW AGRFRTIRS**TVPFLKG*STIKLHRPSTSGEM LDRCMVSTLAAKRMPMSSQVP*CMP*KC*IHRK QGQHCLDKTHNYLLKFKMAHPKKNWKFKEDNYKN SNGKRSWSGKGWSEKEWKEKGWRERG*KGKGWR GSDWNKNSWRERDKNGNGRNAWSGRNAWSGRNA WSGRNAWIGRGKKDKNERGWRDWNGRGKKGSDKS S*KGNSWNGRESAEYQVLLPLPLLRLL*TLCWE TLLLLSQACRQPLSRPRLHPNRALSWDHLHLHL LHHSHQGLHRLQ*PSLLPQGPLHLLHSHPPGLHR PLLPLLSLIKYPLLLHHLLPHPSLHLDSFWHPC QKTIAL*LDLQLQLPEQNLGKCHGWRIPLSQVE GMLLV*TPPHLKQIQAVEMDPFL*GVVV*WKK*V PCWPGGEELLKRDQQ*KQNKKRTKVKIQSL*LL RPLQQVHLNQQENLGKEQIQ*MAASHLLSPDQN PHPYHSPVPMESRRKDLTMTG*SRTF*MK*EKN* QS*KKSSLMQSGRN*ASQILHRGTD*GEIGL*S GGKISYKQQLFTTANPYIYEL*EENGDKQKEGK TNLL*KPSDIMTLVISSFPLRLLLFSGLYNRMEE NHLRVPVTVMQKILKPIRQDHHALKYFHIKIKS HIFHNTLLK*RGERLRKFFCRECW*RIEQVCYC IVMFLSGLFFLSCLIFHE*LRSALCKLRS*YVEQ MEL*VLSKGNIYKKVSEKCFFSLRNFRMIGSFS S*PSCNFVD*NIKFVQNLKI*MPS*IVTMLYQI YDFYITQTSGQM*TLYCRFTVGFQPFLDLCMWTF L*CNYNHHKVSFFNCRQ*CMSH*YVVAFSRPSP RENIL*SIGEWEEGEE*FFI*S*FLHYLFLSYL HE*IMRNIL*L*LVNMLQNQVLNLLHHVFSYLYF NQ*FQWSET*F*ASHNILTVELKSLITEFGSYY YLGTPAVTQVFRYVFLNEAAFEFCYVEMQEITM MAAIKVTEIIR*RKTNEEFCSFLLISKVRLGWWE EGRWEEGIRHSACHSACVCSRARAVYMEATPFS FL*NW*G*NRGEILHVGMIAFWKI*ETLQALHL DLCLSCYVPYLL*TLIIRSFTKTLK*FTFICFLD FVHLSP*SKAC**CSFLNAANLQPLPLQRSLDE GFFFSLSK*FLFL*KFHF*IKL*WMSYHNSSIH FFFLSDIHCHAVVVKTSKMQQAY*VLFSKRNRRH FHLYYCTFGYANTLII*TVMSPINLVSNLF*FC WVS*IVCSR*STGYKWSKLR*ETKIKC*ILKET GFMH*TFCALV*Y*HDVCVN*QKKKKKKTSVESC YISHHPRLLNVLSKKSE*IIIYICYHT*QLCHY *RFQ*LKWETEA*VIYLIKTTFLGTTLL*WFLC SCTLDVLS*VQFRGSFLMTGRHCFPQHCDLTCDK SVLSTM*MAHKSIANKLNVQILVLVLKSLQNSH HDLKVCLKICKHQVSIKTEDETLMNVEFSCF*V YFLFRIFSFLLFLP*LFRLNLFHLSFLHANFVCA IEIKLQYIYVACL*HLDNLLK*FVLK*VILDVK NTF*SPRLYYLKVYMSRHYSLQIS*KS*ILSNV YKRNM**CVYFLFEITVGCSLFLFSLCPP*HSNF LL*SR**LSV*FLFHFVLQHVQVLKTHSCS*NY PLCSLHGKGHCVVKGIIE**ILSIAKYV*CLYM MLIS*NLHISSSTFSLL*SINFEFHFIILMSSLE IQKYNPCIFSLTRPKFSPSPLHSPLHFSWTACS QYSLTFAAITELQL*NFQLFFFFFFCSSLSHVL ASLHM*VSIFVYKLKVTCHSKMS*VT**SFKFT* LQLLCLL*IYIYFQCHCEELAF*F*VVLPYEAQ CAKVCYKVSLIPVWPL*FYNTITL*ILPIISSV KVTI*SKHRKGTLQELLIPLCSYHKIHFPEDIYS HSLPNSKPFSGSTTFVFNRKMSSYLYISPKL*G MRKGS*YIEITDV*YLCLFTKSHLIFLKSKLDI QVFIRNLHDSEGMKLM*VALAM*RHSRGQLLKEE FSFEDL*I*LSS*SQ*PLKKVRL*KPRTVGGL* CRFFCSQHQKLWIIWCVPLYVISR*FLRHQDFL KYQYWKDETFKLKPKID*KEK*NINAVNLGWLQI LTININKWSSRINYLWNTNGQVT*E*NLLVRRH I*QLLKN*LNLSF*IVFFIK*QKHCKRINDCHN DLGCCKNVCHIYWLFLLKSEGIDTSEN*EREIGL SPLQILCDAHNLLNGSVSII*ST**ALSICRLT CRKNQR*SPN*VFEPKNHSH*AAPPFCEAC*IL IKSREQGP*TLLV*DTGILGRGRKLGAPVGG*E* KEYTI*VVLFFFLSF*RHIIPSS*DI*IAR*TG QRREDCLRPEVLRSAWVTGRLISTKKFKNLGQA WWCTPVIPATQETEAGGSPEPREDAAAVSRYHAT VLQPG*QSENLSLKKKKKNSKRI*LFIEIIRKA YIFH*RAQFVRLHLFRKSSIYK*QPIVYHVNLI *LFPSIPRKISSAVDDNSKSIKK*LIKEMDDVIG WFGWVLVNSYSSKKA*KIEN*IVGTLNSIGKST QKKKSTLASV*IES*FSHQVQKFPSKSIETERK GSWLTLKIHIVATI*ERYITERF*KFGLLSA*QS ML*SHL*NLFSFFLFLLFFFLKIKGILKINVSW PGMVAHACNPSTLGG*GGQIT*GQEFETSLANM MKPHLY*KYKKIGWA*WWAPVIPALREAETEESL ESRRWRLQ*AKTAPLYSSLGDRARFHL*INKCF STCFM*EIPAFHYYYQLISGVTWLVLLTEALGI LNMEFPSTH*SSLRFVHPWWQASLTMDSQTPFDC RKS*GHPSASGWASQ*V*GDEFELAVG*FRNSA IAHGWLVKDVDFAT*ISRRRIAYSLSEESNWEG LDIEKKALLKSR*HFLSSLLLEGWEVQA*VRTLQ FGVLPRGTLGLIILSFNCKKKFLTECCSVTQVG VQWCDLGSLQLPPPGFKGIFLPQPPK*LGLQAR ATMPD*FLYF**RWGFTMLPRLVLNS*AQVICPP RPSIAEVFEGRIFDPHIKCPCF*KKTW*KLLLS PCLCHLVGLDFPFSVFLPPSVSLSLSFFVCGVV GRSLDWD*LYQFSGCGASQSFSLSLLPLKLSSFF KFFLFCFYFFLATIQARIDKAFYYYCYYYYFET VSLCHPGWSAVV*FQLTATSASRVQAILLPQPP **LGLQACATTPG*FLYF**RQGFTVLARLVSNS *PQVIHPPWPPKVLGLQA*ATVPIPDKVEF*IS SFTVFSAATGWFILFF*SFLVYSSFDL*REGEK RSEFGSPILSAAFSCFIVIDAIALDSMHPGCKQC GKINGVTILGSVVLHKAPVVCCSVSVSSAPRAF TV*ITSISVVASVHSPLCFNLEAHSAVQKD*FQ SCNGTTRDPCSNYMNSRRSI*LL*FKSCF*VNRL SRAR*SEEALLSIPGQNSVVFISSEPAVLLFIL SLSALKGKKE*SYPPALLILYLPSYPSISM*SF LPSSLVLIQKTLFNSNVLADQVPLPCHLRALSLC FVLGR*R*FGRKSEMEIAVWDDKRWVLFC*HSF TLVLGACPLGFISC*HE*DMLFVRCFSFLENMK CF*QN*MS*KEFYFETSVVDAKYFCNPQ*QYLHI CIEFFF*FLRKPLWSLYL*EHPESPYYVAGGSE RGTATLVL*AEHNFRQSECLLSSHWKLSVAQPL ADFRTFYLSQVWWCVLLGTATRGAEAEGSLEPKV GGQPGQHSEACLLKK*INK**INK*IKTLSLTI VLSAAPL*GWGWGQNKHVHEWRKALVVFVCLFV F*EVGESAVNLSG*RTTYIISIMRFRRLNTFFFQ AYQVDRPKVYSRTAQ*KKFKSEFLMVQKDG*SQ SITFHNICWNWNLLSSCFALNFRTRSVHVCQKI MQSYFLC*QCKHLHPMNGTL*SGSEPKVAYTEVM F*KLRLT*TYTRLYFNCN*KSFTMHTEPHVSYH GICELMGLAEFKGKGNW*QLVLNQHTISSCLLD SSCLKI*IKQDLIVRKHLLSLTSTFKKGTWKRR* DMKLKQLGG*DQTAPDFWTKVSYRNK*KGGPLV SQPRKDLPESSSSCCKIQCLQNDSLCELHAISC NHKV*PVCA*HVSRMCKVRIQQEGAWPCHCGGSV DLLKSLDSCDLGLQHQTPVFALSGHIVEIGSIS PSAFFPTLQLCWF*LLHSSASWYPFFF*NKNMK YLI

Frame 2

VPRGDPDSPPAAAAAAGCTRPRRRRGERGPVER RPGARPRRAPLRGRPRKLREEEQDHEEVGGGGR LGTSSAPRPLRPLPSLSLALFSHTPGRRLGFVR GDGVAPWPPKEEPDTCLPSPSCSPPLEERPPPRL GAFCVSRLVGKPLRRRHHE*TEYLSGKSCCDGL **CQ*EVGASWWLNWIQQSSYLSPYRQQHIQSG GQEDSGPSGRDKLCHS*RVEVQSSYTDLPPVARC *TGVWSQLWQQRGCQCLRKCHDACLRSVKFTGN RANIA*TKLTTTCSSSKWPIPRRIGNSKKTTTR TATAKGAGAGKAGARKNGKRKVGEREVRKGKAGE GATGTRTAGERETRTGTAGTPGAAGTPGAAGTP GAAGTPGSGEARKTRTREAGETGTGEARKGATR AVRKGTAGMGERAQNIKCCCPCLC*DSSKLCAGR LFCF*ARLAGSLSAGRDSIPTGHCLGTTCTSTS STTPTRACTGFSSPPSSPRAPSTSSTPIHRAST APSSPSSP*SSTPSSSTTSCPTPPCIWILFGIHV RRQSPFNWTCSCNCRSKT*ESVTDGGYLFPKWR ECYWCELRLI*NRYRPWKWTPSFRG*WFNGRNE CPAGQEEKNC*KGINNRNRTKRGQR*RFRACNF* GLFNKYT*TNKKTLGKNKYNEWQQVTCYLQTKI HTLITAQCQWSPDGRT*L*QAEAGHFR*NEKRI NKAKRRAH*CNQAGTEQVKYCIEEQTKER*DFNL EEKYPTNNNCSQQQTPTFMSCKKKMETNRRREK PTYSESLQTL*LW**ALSLSVCCFFLAFTTEWK RII*EFL*QLCRKY*NPSGKITTH*NIFISR*SR TFSTIHC*NKEEKGLGSFFAESAGKELSKFAIV L*CFSQVCSSYHV*YSMNN*DQPYVS*DHNMWN KWNCKCFQRVIFIRKCPKNVSSA*EILE**EVSR VSLHAIL*IKT*NLSRT*RFRCLPKLLQCFTKS MTST*HKPVVKCKHYIVDLL*VFNLF*IYACGH FYNVITITTRLAFLIADSNACHTNM*WPFQGLVP GKTFCRV*GSGRKGRNNFLFKVDFCTIFFSVTC MNK**EIFCDFNW*ICYKTKYLIFYIMSSAICI LTSNFNGLKHDSELHIIS*LWNSKV*SLNLAVII T*VPPLLHRCLDTCS*MKLLLNFVMLKCKK*Q* WQQLRSQKSLGKGKPMRSSAVFF**VK*DLGGG KKEGGKKELDTLPATLRVCALAHVLSIWKPLPFL SFETGKVKIGEKSYMLE**LFGKFKKLSRLSIL IYA*VVMCHICFEL*LSEVLLKL*NNSLSSAF* ILYISVHKAKLVDSVVF*TLQICSLYHYKEVWMR DFFFLCQNSSCFCRNFIFRLNCDG*AIIIQVYI SFFYQIFIVMQ***KHQRCSKLIKYYFLKEIGG IFIFIIVLLVMQTL**YKQLCPL*IWSATSFDFV G*VK*SVVGRVLGTSGPN*DKRLK*NAKS*KKL GLCTKRFVPWSNINMMYV*TDKKKKKKKPVLNH AIFPIIPDC*MFFPRSLNELLYTFAIIHDSCVII RDFSN*NGKQKPKLFTLSKPRSLEPHYYDGFCA LVRWMS*AEYSLGDPF**QEGTAFLNTVI*PVT SLYYPLCKWLTSQLQTN*MYKS*CWC*NLFRIVI MI*KFV*KFASIKCQSKLKMKH**MLNSHAFRC TSFLEFSVFCYFYRNYFV*ICFI*VSYTLTSFV RLK*NCSIYMLLVCDT*IIF*NNLF*SKLYWM*K TPFKVQDFTT*KFTCHVTILYRFHRSREY*VMY TKEICDDVSTFCLK*LLGVPSSYFLSAHLDTVT SSYSQDDD*VFNFYSILFCNTFRYLKLIHAVRII LYVVCMVKDIVW*RALLSNEF*V*QNMYSVYT* C*FLKTYI*AVVLFLYYKVLILSSIL*F*CLH* KYKNTILVFFL*PDPNFPLPPSILLSTSRGPRVP NIH*HLQPLQSYSCKIFSCFFFFFFALACLMFL LLFICKSVFLSTN*KSLVIQK*VK*HDNLLNLP SYNFYVSCKFIYTFSAIVKNWPFNSK*YYPMKHS VQRYATRSL*FLCGHYNFITPLPFKFYRL*AA* K*LYKANIAKELCRSS*FLYVAIIKFTFLKTFT LIHFQTPNLFLVAPLLFLIER*VHICTSLQSSKE *EKDPSILKLLMFNTSAFSLKAI*YF*SQNLTY RYL*GISMTLKE*N*CR*LWLCKDIVEDNYLKK SFLLRICRFD*AAEVSNPSRKSVYRSQELLEVCD AGFSVPNIKSCGLFGVFPFMLSLDNF*DIKIF* NINTGKMKPSN*NLKLIRKKSKILMQ*I*DGYR YSPST*INGVLG*IICGILMVKSHKSKIFW*GDT FDNC*RIN*ICLSK*FSL*SNRNIVKG*MTVIM T*DVVRMSATFIGYFC*NLKESIHLKIEKGK*D CPRYRYSVMHTTF*TEVLVSFKAHSRP*VFAD*H AEKIKDEAPIKCLNQRITVTELHPRSVKHVKYS *RAESRARRRFWCRTQEF*AEGEN*GPQLVAES KKNIPFE*CCSFSSVFKDI*FLVVRTSK*LGKLV RGGRIA*GQKF*DQPG*QGDSFLQKNLKI*ARH GGAHL*SQLLRRLKREDHLSPGRTRLQ*AVIMP LYSSLGDRARTCL*KKKKKILREYSFS*KLLEKL TYFIREPSLLDYIYSVKVLYTNDNP*FIM*I*F NCSLQFQERFLQQ*MTILKA*RNN**RRWMML* VGLVGF**IVILLRRLRKSRIE*LVL*IP*EKAL RRKSLHWLVFRLRVNFPIKSKSFHPSL*KLREK VLGLHLKYTLLQPYKRDTLQNAFKNLVS*APNS PCFSHICETSFLFFFFFYFFF*RLKAF*K*MFHG RAWWLTPVIPALWEAEVGRSPEVRSLRPAWPT* *NPISTKNTKKLAGHSGGHL*SQLFGRLRQKSR LNPGGGGCSELRPRHCTPAWATERDSISK*INVF QRVLCEKYQLFIITTS*SQVSLGWFC*PRHWAF *IWSFPPPIDQV*GLSILGGRLA*PWIHKPHLI VVSHKATPVPVVGHHSESEVMNLS*L*ASSATQQ *PMDGW*KTLTLPLKFPGEE*LIVYLRKVIGKA *ILRRKPC*NLGSISFLLYY*RDGRFRPESGLY NLVSFPEVLWA*SF*VSIAKKNF*RSVALSLRLE CSGAISAHCNFPPLGSKGFSCLSLPSSWDYRRV PPCPTNFCIFSRDGVSPCCPGWS*TPELR*SAR LGLQLQKFLKGEYLILT*NVLVSERKHGKNCY*V HVFATLLDLISLSLCSSRPQSLSVCPFLCVELW AGHWTGTDFTSFQAVGLVSHSL*AFYL*S*VLF LNSFCFVFIFSLPLYKQG*IKLFIIIVIIIISRQ SRSVIQAGVQWCDFSSLQPLPPGFKRFSYLSLL SSWDYRHAPPHPANFCIFSRDRVSPYWPGWSRT PDLR*STHLGLPKCWDYRHKRPCPSPIKLSSEFP LSLYSRQLLVGLFFFFNLFWFILLLIFEEKEKK DLSLALPS*VQLLVVL*S*TLLHWTACILDVNN AEKSME*PSWGQWCCIKHQWCAVLCQFPLRHVLS QFELPASLWWLQYILHCASTWKHILPFRKTDSN HVMGPHEIHAPII*IAEGPFDSCSSRAVSK*TD FPELDEVKKPFFQFLGRIQWFSYHLNLLCCCLFY HCQP*KEKRNNLTLLPFLFYIFHLIHLYPCSHS FRVPWF*SKRLCLTAMSWQTRCRFRAI*GL*VF ASS*EDKDNLAESQRWK*QFGMIKDGSCFADILL LWFLVRVLWDSFLASMNRTCFSLGAFLFWRT*S VSNKTE*ARKNSILRHL*LMQSISVILNDSTYI FA*NFFFNF*GNLSGVCIYRSILKVPIM*LVGAR EGQPHSCCEQSTTSGRVNAF*VLIGSFLLLSLW QISEPST*ARCGGACS*AQRLGGLRQKDHLSPK LEASLGNIARPVSLKNK*INNK*INK*KPCP*LL CCLLPLCRDGVGVRISMCMNGGKLWWCLFVCLF FERWGSQQ*TFLVKEQRT*FLL*DLEG*ILFFF RPTKLIDQKYIVEQHSRKNLKVNFLWSKRMDSHS P*PFIIYAGIGISCHLALL*ILELEVCMYVKRL CRAIFFANNVNICTP*MGLYNLEVSLRLRILKS CFKS*G*LKHIQGCILIVTRNHLLCIQNLMYLIM EFVN*WALPNSRVRETGNNLF*INIL*APACLT QVV*KSELNRISLSGNIF*A*HLRLRRERGREG ET*N*NSWEGRIRLHLIFGPKFHIGINKKEDHL* ANLGRTCQKVAAPAAKYSAFKMILCVNCMQFHV TIKCNLYVHDMCLECVKLGFSRKGPGPVTVVDQ WTC*SHWTHVT*VCSIRPLCLH*VATSLKSDQSL PQLSFLLCSFAGFNCFILLLLGILFSFEIKT*N T*F

Sequence NM_001008493

GGGTTCCTCGCGGCGATCCCGACTCTCCTCCCGCGGCTGCAGCAGCTGCCGGTTGCACACGGCCTCGGCGGCGGCGCGGCGAGCGCGGGCCTGTGGAGCG GCGGCCGGGCGCGCGGCCCCGGCGGGCACCCCTCAGAGGGCGGCCGAGGAAGCTCCGGGAGGAGGAGCAGGACCACGAGGAGGTGGGAGGCGGCGGCCGC CTGGGGACCAGCTCCGCGCCTCGGCCTCTCCGCCCCCTCCCCAGCCTTTCTCTCGCCCTCTTCTCCCACACTCCCGGCCGGCGCCTCGGCTTTGTGCGAG GAGATGGTGTAGCCCCCTGGCCGCCGAAGGAGGAGCCGGACACTTGTCTCCCGTCTCCGAGCTGCTCCCCACCCCTGGAGGAGAGACCCCCCCCTCGGCT CGGCGCCTTCTGCGTCTCCCGGCTGGTGGGGAAGCCTCTGCGCCGCCGGCACCATGAGTGAACAGAGTATCTGTCAGGCAAGAGCTGCTGTGATGGTTTA TGATGATGCCAATAAGAAGTGGGTGCCAGCTGGTGGCTCAACTGGATTCAGCAGAGTTCATATCTATCACCATACAGGCAACAACACATTCAGAGTGGTG GGCAGGAAGATTCAGGACCATCAGGTCGTGATAAACTGTGCCATTCCTAAAGGGTTGAAGTACAATCAAGCTACACAGACCTTCCACCAGTGGCGAGATG CTAGACAGGTGTATGGTCTCAACTTTGGCAGCAAAGAGGATGCCAATGTCTTCGCAAGTGCCATGATGCATGCCTTAGAAGTGTTAAATTCACAGGAAAC AGGGCCAACATTGCCTAGACAAAACTCACAACTACCTGCTCAAGTTCAAAATGGCCCATCCCAAGAAGAATTGGAAATTCAAAGAAGACAACTACAAGAA CAGCAACGGCAAAAGGAGCTGGAGCGGGAAAGGCTGGAGCGAGAAAGAATGGAAAGAGAAAGGTTGGAGAGAGAGAGGTTAGAAAGGGAAAGGCTGGAGA GGGAGCGACTGGAACAAGAACAGCTGGAGAGAGAGAGACAAGAACGGGAACGGCAGGAACGCCTGGAGCGGCAGGAACGCCTGGAGCGGCAGGAACGCCT GGAGCGGCAGGAACGCCTGGATCGGGAGAGGCAAGAAAGACAAGAACGAGAGAGGCTGGAGAGACTGGAACGGGAGAGGCAAGAAAGGGAGCGACAAGAG CAGTTAGAAAGGGAACAGCTGGAATGGGAGAGAGAGCGCAGAATATCAAGTGCTGCTGCCCCTGCCTCTGTTGAGACTCCTCTAAACTCTGTGCTGGGAG ACTCTTCTGCTTCTGAGCCAGGCTTGCAGGCAGCCTCTCAGCCGGCCGAGACTCCATCCCAACAGGGCATTGTCTTGGGACCACTTGCACCTCCACCTCC TCCACCACTCCCACCAGGGCCTGCACAGGCTTCAGTAGCCCTCCCTCCTCCCCCAGGGCCCCCTCCACCTCCTCCACTCCCATCCACCGGGCCTCCACCG CCCCCTCCTCCCCCTCCTCTCCCTAATCAAGTACCCCCTCCTCCTCCACCACCTCCTGCCCCACCCCTCCCTGCATCTGGATTCTTTTTGGCATCCATGT CAGAAGACAATCGCCCTTTAACTGGACTTGCAGCTGCAATTGCCGGAGCAAAACTTAGGAAAGTGTCACGGATGGAGGATACCTCTTTCCCAAGTGGAGG GAATGCTATTGGTGTGAACTCCGCCTCATCTAAAACAGATACAGGCCGTGGAAATGGACCCCTTCCTTTAGGGGGTAGTGGTTTAATGGAAGAAATGAGT GCCCTGCTGGCCAGGAGGAGAAGAATTGCTGAAAAGGGATCAACAATAGAAACAGAACAAAAAGAGGACAAAGGTGAAGATTCAGAGCCTGTAACTTCTA AGGCCTCTTCAACAAGTACACCTGAACCAACAAGAAAACCTTGGGAAAGAACAAATACAATGAATGGCAGCAAGTCACCTGTTATCTCCAGACGGGATTC TCCAAGGAAAAATCAGATTGTTTTTGACAACAGGTCCTATGATTCATTACACAGACCAAAATCCACACCCTTATCACAGCCCAGTGCCAATGGAGTCCAG ACGGAAGGACTTGACTATGACAGGCTGAAGCAGGACATTTTAGATGAAATGAGAAAAGAATTAACAAAGCTAAAAGAAGAGCTCATTGATGCAATCAGGC AGGAACTGAGCAAGTCAAATACTGCATAGAGGAACAGACTAAGGAGAGATAGGACTTTAATCTGGAGGAAAAATATCCTACAAACAACAACTGTTCACAA CAGCAAACCCCTACATTTATGAGCTGTAAGAAGAAAATGGAGACAAACAGAAGGAGGGAAAAACCAACCTACTCTGAAAGCCTTCAGACATTATGACTCT GGTGATAAGCTCTTTCCCTCTCCGTTTGCTGCTTTTTTCTGGCCTTTACAACAGAATGGAAGAGAATCATTTAAGAGTTCCTGTAACAGTTATGCAGAAA ATACTAAAACCCATCAGGCAAGATCACCACGCATTGAAATATTTTCATATCAAGATAAAGTCGCACATTTTCCACAATACATTGCTAAAATAAAGAGGAG AAAGGCTTAGGAAGTTTTTTTGCAGAGAGTGCTGGTAAAGAATTGAGCAAGTTTGCTATTGTATTGTAATGTTTCTCTCAGGTTTGTTCTTCCTATCATG TTTGATATTCCATGAATAATTGAGATCAGCCCTATGTAAGTTAAGATCATAATATGTGGAACAAATGGAATTGTAAGTGCTTTCAAAGGGTAATATTTAT AAGAAAGTGTCCGAAAAATGTTTCTTCAGCTTGAGAAATTTTAGAATGATAGGAAGTTTCTCGAGTTAGCCTTCATGCAATTTTGTAGATTAAAACATAA AATTTGTCCAGAACTTAAAGATTTAGATGCCTTCCTAAATTGTTACAATGCTTTACCAAATCTATGACTTCTACATAACACAAACCAGTGGTCAAATGTA AACACTATATTGTAGATTTACTGTAGGTTTTCAACCTTTTTTAGATTTATGCATGTGGACATTTTTATAATGTAATTACAATCACCACAAGGTTAGCTTT TTTAATTGCAGACAGTAATGCATGTCACACTAATATGTAGTGGCCTTTTCAAGGCCTAGTCCCAGGGAAAACATTTTGTAGAGTATAGGGGAGTGGGAGG AAGGGGAGGAATAATTTTTTATTTAAAGTTGATTTCTGCACTATCTTTTTCTCAGTTACCTGCATGAATAAATAATGAGAAATATTTTGTGACTTTAATT GGTAAATATGTTACAAAACCAAGTACTTAATCTTTTACATCATGTCTTCAGCTATTTGTATTTTAACCAGTAATTTCAATGGTCTGAAACATGATTCTGA GCTTCACATAATATCTTAACTGTGGAACTCAAAAGTTTGATCACTGAATTTGGCAGTTATTATTACCTAGGTACCCCCGCTGTTACACAGGTGTTTAGAT ACGTGTTCCTGAATGAAGCTGCTTTTGAATTTTGTTATGTTGAAATGCAAGAAATAACAATGATGGCAGCAATTAAGGTCACAGAAATCATTAGGTAAAG GAAAACCAATGAGGAGTTCTGCAGTTTTCTTTTAATAAGTAAAGTGAGACTTGGGTGGTGGGAAGAAGGAAGGTGGGAAGAAGGAATTAGACACTCTGCC TGCCACTCTGCGTGTGTGTGCTCTCGCGCACGTGCTGTCTATATGGAAGCCACTCCCTTTTCTTTCCTTTGAAACTGGTAAGGTTAAAATAGGGGAGAAA TCCTACATGTTGGAATGATAGCTTTTTGGAAAATTTAAGAAACTCTCCAGGCTCTCCATCTTGATTTATGCTTGAGTTGTTATGTGCCATATTTGCTTTG AACTCTGATTATCAGAAGTTTTACTAAAACTTTGAAATAATTCACTTTCATCTGCTTTCTAGATTTTGTACATCTCAGTCCATAAAGCAAAGCTTGTTGA TAGTGTAGTTTTCTAAACGCTGCAAATTTGCAGCCTTTACCACTACAAAGAAGTTTGGATGAGGGATTTTTTTTTTCTTTGTCAAAATAGTTCCTGTTTC TGTAGAAATTTCATTTTTAGATTAAACTGTGATGGATGAGCTATCATAATTCAAGTATACATTTCTTTTTTCTATCAGATATTCATTGTCATGCAGTAGT AGTAAAAACATCAAAGATGCAGCAAGCTTATTAAGTATTATTTTCTAAAAGAAATAGGAGGCATTTTCATCTTTATTATTGTACTTTTGGTTATGCAAAC ACTTTGATAATATAAACAGTTATGTCCCCTATAAATCTGGTCAGCAACCTCTTTTGATTTTGTTGGGTAAGTTAAATAGTCTGTAGTAGGTAGAGTACTG GGTACAAGTGGTCCAAACTAAGATAAGAGACTAAAATAAAATGCTAAATCTTAAAAGAAACTGGGTTTATGCACTAAACGTTTTGTGCCTTGGTCTAATA TTAACATGATGTATGTGTAAACTGACAAAAAAAAAAAAAAAAAAAAACCAGTGTTGAATCATGCTATATTTCCCATCATCCCAGATTGCTAAATGTTCTT TCCAAGAAGTCTGAATGAATTATTATATACATTTGCTATCATACATGACAGTTGTGTCATTATTAGAGATTTCAGTAATTAAAATGGGAAACAGAAGCCT AAGTTATTTACCTTATCAAAACCACGTTCCTTGGAACCACATTATTATGATGGTTTTTGTGCTCTTGTACGTTGGATGTCTTAAGCTGAGTACAGTTTAG GGGATCCTTTCTAATGACAGGAAGGCACTGCTTTCCTCAACACTGTGATCTGACCTGTGACAAGTCTGTACTATCCACTATGTAAATGGCTCACAAGTCA ATTGCAAACAAACTGAATGTACAAATCTTAGTGCTGGTGCTGAAATCTCTTCAGAATAGTCATCATGATTTAAAAGTTTGTTTAAAAATTTGCAAGCATC AAGTGTCAATCAAAACTGAAGATGAAACACTAATGAATGTTGAATTCTCATGCTTTTAGGTGTACTTCCTTTTTAGAATTTTCAGTTTTCTGCTATTTTT ACCGTAACTATTTCGTTTAAATTTGTTTCATTTAAGTTTCCTACACGCTAACTTCGTTTGTGCGATTGAAATAAAATTGCAGTATATATATGTTGCTTGT TTGTGACACTTAGATAATCTTCTGAAATAATTTGTTTTAAAGTAAGTTATATTGGATGTGAAAAACACCTTTTAAAGTCCAAGACTTTACTACTTAAAAG TTTACATGTCACGTCACTATTCTTTACAGATTTCATAGAAGTCGTGAATACTAAGTAATGTATACAAAAGAAATATGTGATGATGTGTCTACTTTTTGTT TGAAATAACTGTTGGGTGTTCCCTCTTCTTATTTTCTCTCTGCCCACCTTGACACAGTAACTTCCTCTTATAGTCAAGATGATGATTAAGTGTTTAATTT TTATTCCATTTTGTTCTGCAACACGTTCAGGTACTTAAAACTCATTCATGCAGTTAGAATTATCCTTTATGTAGTTTGCATGGTAAAGGACATTGTGTGG TAAAGGGCATTATTGAGTAATGAATTTTAAGTATAGCAAAATATGTATAGTGTTTATACATGATGCTGATTTCTTAAAACCTACATATAAGCAGTAGTAC TTTTTCTCTATTATAAAGTATTAATTTTGAGTTCCATTTTATAATTCTGATGTCTTCATTAGAAATACAAAAATACAATCCTTGTATTTTTTCTTTGACC AGACCCAAATTTTCCCCTTCCCCCCTCCATTCTCCTCTCCACTTCTCGTGGACCGCGTGTTCCCAATATTCATTAACATTTGCAGCCATTACAGAGTTAC AGTTGTAAAATTTTCAGCTGTTTTTTTTTTTTTTTTTTTGCTCTAGCCTGTCTCATGTTCTTGCTTCTCTTCATATGTAAGTCAGTATTTTTGTCTACAA ATTAAAAGTCACTTGTCATTCAAAAATGAGTTAAGTAACATGATAATCTTTTAAATTTACCTAGCTACAACTTTTATGTCTCTTGTAAATTTATATATAC TTTCAGTGCCATTGTGAAGAATTGGCCTTTTAATTCTAAGTAGTATTACCCTATGAAGCACAGTGTGCAAAGGTATGCTACAAGGTCTCTTTAATTCCTG TGTGGCCATTATAATTTTATAACACCATTACCCTTTAAATTCTACCGATTATAAGCAGCGTAAAAGTAACTATATAAAGCAAACATCGCAAAGGAACTCT GCAGGAGCTCTTAATTCCTTTATGTAGCTATCATAAAATTCACTTTCCTGAAGACATTTACTCTCATTCACTTCCAAACTCCAAACCTTTTTCTGGTAGC ACCACTTTTGTTTTTAATAGAAAGATGAGTTCATATCTGTACATCTCTCCAAAGCTCTAAGGAATGAGAAAAGGATCCTAGTATATTGAAATTACTGATG TTTAATACCTCTGCCTTTTCACTAAAAGCCATTTAATATTTTTAAAGTCAAAACTTGACATACAGGTATTTATAAGGAATCTCCATGACTCTGAAGGAAT GAAATTGATGTAGGTAGCTTTGGCTATGTAAAGACATAGTAGAGGACAATTACTTAAAGAAGAGTTTTCTTTTGAGGATTTGTAGATTTGACTAAGCAGC TGAAGTCAGTAACCCCTCAAGAAAGTCCGTTTATAGAAGCCAAGAACTGTTGGAGGTCTGTGATGCAGGTTTTTCTGTTCCCAACATCAAAAGCTGTGGA TTATTTGGTGTGTTCCCCTTTATGTTATCTCTCGATAATTTTTGAGACATCAAGATTTTTTAAAATATCAATACTGGAAAGATGAAACCTTCAAATTAAA ACCTAAAATTGATTAGAAAGAAAAGTAAAATATTAATGCAGTAAATTTAGGATGGTTACAGATACTCACCATCAACATAAATAAATGGAGTTCTAGGATA AATTATTTGTGGAATACTAATGGTCAAGTCACATAAGAGTAAAATCTTTTGGTGAGGAGACACATTTGACAACTGCTAAAGAATTAACTAAATTTGTCTT TCTAAATAGTTTTCTTTATAAAGTAACAGAAACATTGTAAAAGGATAAATGACTGTCATAATGACTTAGGATGTTGTAAGAATGTCTGCCACATTTATTG GTTATTTCTGTTGAAATCTGAAGGAATCGATACATCTGAAAATTGAGAAAGGGAAATAGGACTGTCCCCGTTACAGATACTCTGTGATGCACACAACCTT CTAAACGGAAGTGTTAGTATCATTTAAAGCACATAGTAGGCCTTGAGTATTTGCAGATTAACATGCAGAAAAAATCAAAGATGAAGCCCCAATTAAGTGT TTGAACCAAAGAATCACAGTCACTGAGCTGCACCCCCGTTCTGTGAAGCATGTTAAATACTCATAAAGAGCAGAGAGCAGGGCCCGTAGACGCTTCTGGT GTAGGACACAGGAATTCTAGGCAGAGGGAGAAAATTAGGGGCCCCAGTTGGTGGCTGAGAGTAAAAAGAATATACCATTTGAGTAGTGCTGTTCTTTTTC CTCAGTTTTTAAAGACATATAATTCCTAGTAGTTAGGACATCTAAATAGCTCGGTAAACTGGTCAGAGGCGGGAGGATTGCTTGAGGCCAGAAGTTTTGA GATCAGCCTGGGTAACAGGGAGACTCATTTCTACAAAAAAATTTAAAAATTTAGGCCAGGCATGGTGGTGCACACCTGTAATCCCAGCTACTCAGGAGAC TGAAGCGGGAGGATCACCTGAGCCCAGGGAGGACGCGGCTGCAGTGAGCCGTTATCATGCCACTGTACTCCAGCCTGGGTGACAGAGCGAGAACCTGTCT CTAAAAAAAAAAAAAAAAAATTCTAAGAGAATATAGCTTTTCATAGAAATTATTAGAAAAGCTTACATATTTCATTAGAGAGCCCAGTTTGTTAGACTAC ATTTATTCCGTAAAAGTTCTATATACAAATGACAACCCATAGTTTATCATGTAAATCTGATTTAACTGTTCCCTTCAATTCCAAGAAAGATTTCTTCAGC AGTAGATGACAATTCTAAAAGCATAAAGAAATAACTAATAAAGGAGATGGATGATGTTATAGGTTGGTTTGGTTGGGTTTTAGTAAATAGTTATTCTTCT AAGAAGGCTTAGAAAATCGAGAATTGAATAGTTGGTACTTTGAATTCCATAGGAAAAAGCACTCAGAAGAAAAAGTCTACATTGGCTAGTGTTTAGATTG AGAGTTAATTTTCCCATCAAGTCCAAAAGTTTCCATCCAAGTCTATAGAAACTGAGAGAAAAGGTTCTTGGCTTACACTTAAAATACACATTGTTGCAAC CATATAAGAGAGATACATTACAGAACGCTTTTAAAAATTTGGTCTCTTAAGCGCCTAACAGTCCATGCTTTAGTCACATCTGTGAAACCTCTTTTCTTTT TTTCTTTTTCTTTTATTTTTTTTTTTAAAGATTAAAGGCATTTTAAAAATAAATGTTTCATGGCCGGGCATGGTGGCTCACGCCTGTAATCCCAGCACTT TGGGAGGCTGAGGTGGGCAGATCACCTGAGGTCAGGAGTTTGAGACCAGCCTGGCCAACATGATGAAACCCCATCTCTACTAAAAATACAAAAAAATTGG CTGGGCATAGTGGTGGGCACCTGTAATCCCAGCTCTTCGGGAGGCTGAGACAGAAGAGTCGCTTGAATCCAGGAGGTGGAGGTTGCAGTGAGCTAAGACC GCGCCACTGTACTCCAGCCTGGGCGACAGAGCGAGATTCCATCTCTAAATAAATAAATGTTTTTCAACGTGTTTTATGTGAGAAATACCAGCTTTTCATT ATTACTACCAGTTGATCTCAGGTGTCACTTGGTTGGTTCTGCTGACCGAGGCACTGGGCATTTTAAATATGGAGTTTCCCTCCACCCATTGATCAAGTCT GAGGTTTGTCCATCCTTGGTGGCAGGCTAGCTTAACCATGGATTCACAAACCCCATTTGATTGTCGTAAGTCATAAGGCCACCCCAGTGCCAGTGGTTGG GCATCACAGTGAGTCTGAGGTGATGAATTTGAGTTAGCTGTAGGCTAGTTCCGCAACTCAGCAATAGCCCATGGATGGTTGGTAAAAGACGTTGACTTTG CCACTTAAATTTCCAGGAGAAGAATAGCTTATAGTTTATCTGAGGAAAGTAATTGGGAAGGCTTAGATATTGAGAAGAAAGCCCTGTTAAAATCTAGGTA GCATTTCCTTTCTTCTTTATTACTAGAGGGATGGGAGGTTCAGGCCTGAGTCAGGACTTTACAATTTGGTGTCCTTCCCAGAGGTACTTTGGGCTTGATC ATTTTAAGTTTCAATTGCAAAAAAAAATTTTTGACGGAGTGTTGCTCTGTCACTCAGGTTGGAGTGCAGTGGTGCGATCTCGGCTCACTGCAACTTCCCC CCCCTGGGTTCAAAGGGATTTTCCTGCCTCAGCCTCCCAAGTAGCTGGGACTACAGGCGCGTGCCACCATGCCCGACTAATTTTTGTATTTTTAGTAGAG ATGGGGTTTCACCATGTTGCCCAGGCTGGTCTTGAACTCCTGAGCTCAGGTGATCTGCCCGCCTCGGCCTTCAATTGCAGAAGTTTTTGAAGGGAGAATA TTTGATCCTCACATAAAATGTCCTTGTTTCTGAAAGAAAACATGGTAAAAATTGTTATTGAGTCCATGTCTTTGCCACCTTGTTGGACTTGATTTCCCTT TCTCTGTGTTCCTCCCGCCCTCAGTCTCTCTCAGTCTGTCCTTTTTTGTGTGTGGAGTTGTGGGCAGGTCATTGGACTGGGACTGACTTTACCAGTTTTC AGGCTGTGGGGCTAGTCAGTCATTCTCTCTGAGCCTTCTACCTCTAAAGTTGAGTTCTTTTTTTAAATTCTTTTTGTTTTGTTTTTATTTTTTCCTTGCC ACTATACAAGCAAGGATAGATAAAGCTTTTTATTATTATTGTTATTATTATTATTTCGAGACAGTCTCGCTCTGTCATCCAGGCTGGAGTGCAGTGGTGT GATTTCAGCTCACTGCAACCTCTGCCTCCCGGGTTCAAGCGATTCTCCTACCTCAGCCTCCTTAGTAGCTGGGACTACAGGCATGCGCCACCACACCCGG CTAATTTTTGTATTTTTAGTAGAGACAGGGTTTCACCGTATTGGCCAGGCTGGTCTCGAACTCCTGACCTCAGGTGATCCACCCACCTTGGCCTCCCAAA GTGTTGGGATTACAGGCATAAGCGACCGTGCCCATCCCCGATAAAGTTGAGTTCTGAATTTCCTCTTTCACTGTATTCTCGGCAGCTACTGGTTGGTTTA TTCTTTTTTTTTAATCTTTTTTGGTTTATTCTTCTTTTGATCTTTGAAGAGAAGGAGAAAAAAGATCTGAGTTTGGCTCTCCCATCTTAAGTGCAGCTTT TAGTTGTTTTATAGTCATAGACGCTATTGCACTGGACAGCATGCATCCTGGATGTAAACAATGCGGAAAAATCAATGGAGTGACCATCTTGGGGTCAGTG GTGTTGCATAAAGCACCAGTGGTGTGCTGTTCTGTGTCAGTTTCCTCTGCGCCACGTGCTTTCACAGTTTGAATTACCAGCATCTCTGTGGTGGCTTCAG TACATTCTCCATTGTGCTTCAACCTGGAAGCACATTCTGCCGTTCAGAAAGACTGATTCCAATCATGTAATGGGACCACACGAGATCCATGCTCCAATTA TATGAATAGCAGAAGGTCCATTTGACTCTTGTAGTTCAAGAGCTGTTTCTAAGTAAACAGACTTTCCAGAGCTCGATGAAGTGAAGAAGCCCTTCTTTCA ATTCCTGGGCAGAATTCAGTGGTTTTCATATCATCTGAACCTGCTGTGCTGCTGTTTATTCTATCACTGTCAGCCTTGAAAGGAAAAAAGGAATAATCTT ACCCTCCTGCCCTTCTTATTTTATATCTTCCATCTTATCCATCTATATCCATGTAGTCATTCCTTCCGAGTTCCCTGGTTTTAATCCAAAAGACTCTGTT TAACAGCAATGTCTTGGCAGACCAGGTGCCGCTTCCGTGCCATTTGAGGGCTCTGAGTCTTTGCTTCGTCTTAGGAAGATAAAGATAATTTGGCAGAAAG TCAGAGATGGAAATAGCAGTTTGGGATGATAAAAGATGGGTCCTGTTTTGCTGACATTCTTTTACTTTGGTTCTTGGTGCGTGTCCTTTGGGATTCATTT CTTGCTAGCATGAATAGGACATGCTTTTCGTTAGGTGCTTTTCTTTTTTGGAGAACATGAAGTGTTTCTAACAAAACTGAATGAGCTAGAAAGAATTCTA TTTTGAGACATCTGTAGTTGATGCAAAGTATTTCTGTAATCCTCAATGACAGTACTTACATATTTGCATAGAATTTTTTTTTTAATTTTTGAGGAAACCT CTCTGGAGTCTGTATTTATAGGAGCATCCTGAAAGTCCCTATTATGTAGCTGGTGGGAGCGAGAGAGGGACAGCCACACTCGTGCTGTGAGCAGAGCACA ACTTCAGGCAGAGTGAATGCCTTCTGAGTTCTCATTGGAAGCTTTCTGTTGCTCAGCCTCTGGCAGATTTCAGAACCTTCTACTTAAGCCAGGTGTGGTG GTGCGTGCTCCTAGGCACAGCGACTCGGGGGGCTGAGGCAGAAGGATCACTTGAGCCCAAAGTTGGAGGCCAGCCTGGGCAACATAGCGAGGCCTGTCTC CTTAAAAAATAAATAAATAAATAATAAATAAATAAATAAATAAAAACCTTGTCCTTGACTATTGTGCTGTCTGCTGCCCCTTTGTAGGGATGGGGTTGGG GTCAGAATAAGCATGTGCATGAATGGCGGAAAGCTTTGGTGGTGTTTGTTTGTTTGTTTGTTTTTTGAGAGGTGGGGGAGTCAGCAGTGAACCTTTCTGG TTAAAGAACAACGTACATAATTTCTATTATGAGATTTAGAAGGTTAAATACTTTTTTTTTTCAGGCCTACCAAGTTGATAGACCAAAAGTATATAGTAGA ACAGCACAGTAGAAAAAATTTAAAAGTGAATTTCTTATGGTCCAAAAGGATGGATAGTCACAGTCCATAACCTTTCATAATATATGCTGGAATTGGAATC TCTTGTCATCTTGCTTTGCTCTGAATTTTAGAACTAGAAGTGTGCATGTATGTCAAAAGATTATGCAGAGCTATTTTCTTTGCTAACAATGTAAACATTT GCACCCCATGAATGGGACTTTATAATCTGGAAGTGAGCCTAAGGTTGCGTATACTGAAGTCATGTTTTAAAAGTTAAGGTTGACTTAAACATATACAAGG CTGTATTTTAATTGTAACTAGAAATCATTTACTATGCATACAGAACCTCATGTATCTTATCATGGAATTTGTGAATTAATGGGCCTTGCCGAATTCAAGG GTAAGGGAAACTGGTAACAACTTGTTTTAAATCAACATACTATAAGCTCCTGCTTGCTTGACTCAAGTTGTTTGAAAATCTGAATTAAACAGGATCTCAT TGTCAGGAAACATCTTCTAAGCTTGACATCTACGTTTAAGAAGGGAACGTGGAAGAGAAGGTGAGACATGAAACTAAAACAGCTGGGAGGGTAGGATCAG ACTGCACCTGATTTTTGGACCAAAGTTTCATATAGGAATAAATAAAAAGGAGGACCACTTGTGAGCCAACCTAGGAAGGACTTGCCAGAAAGTAGCAGCT CCTGCTGCAAAATACAGTGCCTTCAAAATGATTCTCTGTGTGAATTGCATGCAATTTCATGTAACCATAAAGTGTAACCTGTATGTGCATGACATGTGTC TAGAATGTGTAAAGTTAGGATTCAGCAGGAAGGGGCCTGGCCCTGTCACTGTGGTGGATCAGTGGACCTGCTGAAGTCACTGGACTCATGTGACTTAGGT TTGCAGCATCAGACCCCTGTGTTTGCATTAAGTGGCCACATCGTTGAAATCGGATCAATCTCTCCCTCAGCTTTCTTTCCTACTTTGCAGCTTTGCTGGT TTTAACTGCTTCATTCTTCTGCTTCTTGGTATCCTTTTTTCTTTTGAAATAAAAACATGAAATACTTAATTC

refseq_ENAH.F1 (forward primer)
refseq_ENAH.R1 (reverse primer)
Single exon skipping

Frame 0

GFLAAIPTLLPRLQQLPVAHGLGGGAASAGLWS GGRARGPGGHPSEGGRGSSGRRSRTTRRWEAAAA WGPAPRLGLSAPSPAFLSPSSPTLPAGASALCE EMV*PPGRRRRSRTLVSRLRAAPHPWRRDPPLG SAPSASPGWWGSLCAAGTMSEQSICQARAAVMVY DDANKKWVPAGGSTGFSRVHIYHHTGNNTFRVV GRKIQDHQVVINCAIPKGLKYNQATQTFHQWRD ARQVYGLNFGSKEDANVFASAMMHALEVLNSQET GPTLPRQNSQLPAQVQNGPSQEELEIQRRQLQE QQRQKELERERLERERMERERLERERLERERLE RERLEQEQLERERQERERQERLERQERLERQERL ERQERLDRERQERQERERLERLERERQERERQE QLEREQLEWERERRISSAAAPASVETPLNSVLG DSSASEPGLQAASQPAETPSQQGIVLGPLAPPPP PPLPPGPAQASVALPPPPGPPPPPPLPSTGPPP PPPPPPLPNQVPPPPPPPPAPPLPASGFFLASM SEDNRPLTGLAAAIAGAKLRKVSRMEDTSFPSGG NAIGVNSASSKTDTGRGNGPLPLGGSGLMEEMS ALLARRRRIAEKGSTIETEQKEDKGEDSEPVTS KASSTSTPEPTRKPWERTNTMNGSKSPVISRRDS PRKNQIVFDNRSYDSLHRPKSTPLSQPSANGVQ TEGLDYDRLKQDILDEMRKELTKLKEELIDAIR QELSKSNTA*RNRLRRDRTLIWRKNILQTTTVHN SKPLHL*AVRRKWRQTEGGKNQPTLKAFRHYDS GDKLFPSPFAAFFWPLQQNGRESFKSSCNSYAE NTKTHQARSPRIEIFSYQDKVAHFPQYIAKIKRR KA*EVFLQRVLVKN*ASLLLYCNVSLRFVLPIM FDIP*IIEISPM*VKIIICGTNGIVSAFKG*YL *ESVRKMFLQLEKF*NDRKFLELAFMQFCRLKHK ICPELKDLDAFLNCYNALPNL*LLHNTNQWSNV NTIL*IYCRFSTFFRFMHVDIFIM*LQSPQG*L F*LQTVMHVTLICSGLFKA*SQGKHFVEYRGVGG RGGIIFYLKLISALSFSQLPA*INNEKYFVTLI GKYVTKPST*SFTSCLQLFVF*PVISMV*NMIL SFT*YLNCGTQKFDH*IWQLLLPRYPRCYTGV*I RVPE*SCF*ILLC*NARNNNDGSN*GHRNH*VK ENQ*GVLQFSFNK*SETWVVGRRKVGRRN*TLC LPLCVCVLSRTCCLYGSHSLFFPLKLVRLK*GRN PTCWNDSFLENLRNSPGSPS*FMLELLCAIFAL NSDYQKFY*NFEIIHFHLLSRFCTSQSIKQSLL IV*FSKRCKFAAFTTTKKFG*GIFFFFVKIVPVS VEISFLD*TVMDELS*FKYTFLFSIRYSLSCSS SKNIKDAASLLSIIF*KK*EAFSSLLLYFWLCK HFDNINSYVPYKSGQQPLLILLGKLNSL**VEYW VQVVQTKIRD*NKMLNLKRNWVYALNVLCLGLI LT*CMCKLTKKKKKKNQC*IMLYFPSSQIAKCS FQEV*MNYYIHLLSYMTVVSLLEISVIKMGNRSL SYLPYQNHVPWNHIIMMVFVLLYVGCLKLSTV* GILSNDRKALLSSTL*SDL*QVCTIHYVNGSQV NCKQTECTNLSAGAEISSE*SS*FKSLFKNLQAS SVNQN*R*NTNEC*ILMLLGVLPF*NFQFSAIF TVTISFKFVSFKFPTR*LRLCD*NKIAVYICCL FVTLR*SSEIICFKVSYIGCEKHLLKSKTLLLKS LHVTSLFFTDFIEVVNTK*CIQKKYVMMCLLFV *NNCWVFPLLIFSLPTLTQ*LPLIVKMMIKCLI FIPFCSATRSGT*NSFMQLELSFM*FAW*RTLCG KGHY*VMNFKYSKICIVFIHDADFLKPTYKQ*Y FFSIIKY*F*VPFYNSDVFIRNTKIQSLYFFFD QTQIFPFPPPFSSPLLVDRVFPIFINICSHYRVT VVKFSAVFFFFFLL*PVSCSCFSSYVSQYFCLQ IKSHLSFKNELSNMIIF*IYLATTFMSLVNLYI LSVPL*RIGLLILSSITL*STVCKGMLQGLFNSC VAIIIL*HHYPLNSTDYKQRKSNYIKQTSQRNS AGALNSFM*LS*NSLS*RHLLSFTSKLQTFFW* HHFCF**KDEFISVHLSKALRNEKRILVY*NY*C LIPLPFH*KPFNIFKVKT*HTGIYKESP*L*RN EIDVGSFGYVKT**RTIT*RRVFF*GFVDLTKQ LKSVTPQESPFIEAKNCWRSVMQVFLFPTSKAVD YLVCSPLCYLSIIFETSRFFKISILER*NLQIK T*N*LERKVKY*CSKFRMVTDTHHQHK*MEF*D KLFVEY*WSSHIRVKSFGEETHLTTAKELTKFVF LNSFLYKVTETL*KDK*LS**LRML*ECLPHLL VISVEI*RNRYI*KLRKGNRTVPVTDTL*CTQP SKRKC*YHLKHIVGLEYLQINMQKKSKMKPQLSV *TKESQSLSCTPVL*SMLNTHKEQRAGPVDASG VGHRNSRQREKIRGPSWWLRVKRIYHLSSAVLF PQFLKTYNS**LGHLNSSVNWSEAGGLLEARSFE ISLGNRETHFYKKI*KFRPGMVVHTCNPSYSGD *SGRIT*AQGGRGCSEPLSCHCTPAWVTEREPV SKKKKKKF*ENIAFHRNY*KSLHISLESPVC*TT FIP*KFYIQMTTHSLSCKSDLTVPFNSKKDFFS SR*QF*KHKEITNKGDG*CYRLVWLGFSK*LFF *EGLENRELNSWYFEFHRKKHSEEKVYIG*CLD* ELIFPSSPKVSIQVYRN*EKRFLAYT*NTHCCN HIREIHYRTLLKIWSLKRLTVHALVTSVKPLFF FSFSFIFFFKD*RHFKNKCFMAGHGGSRL*SQHF GRLRWADHLRSGV*DQPGQHDETPSLLKIQKNW LGIVVGTCNPSSSGG*DRRVA*IQEVEVAVS*D RATVLQPGRQSEIPSLNK*MFFNVFYVRNTSFSL LLPVDLRCHLVGSADRGTGHFKYGVSLHPLIKS EVCPSLVAG*LNHGFTNPI*LS*VIRPPQCQWL GITVSLR**I*VSCRLVPQLSNSPWMVGKRR*LC HLNFQEKNSL*FI*GK*LGRLRY*EESPVKI*V AFPFFFITRGMGGSGLSQDFTIWCPSQRYFGLD HFKFQLQKKIFDGVLLCHSGWSAVVRSRLTATSP PWVQRDFPASASQVAGTTGACHHARLIFVFLVE MGFHHVAQAGLELLSSGDLPASAFNCRSF*REN I*SSHKMSLFLKENMVKIVIESMSLPPCWT*FPF LCVPPALSLSQSVLFCVWSCGQVIGLGLTLPVF RLWG*SVILSEPSTSKVEFFF*ILFVLFLFFPC HYTSKDR*SFLLLLLLLLFRDSLALSSRLECSGV ISAHCNLCLPGSSDSPTSASLVAGTTGMRHHTR LIFVFLVETGFHRIGQAGLELLTSGDPPTLASQ SVGITGISDRAHPR*S*VLNFLFHCILGSYWLVY SFFLIFFGLFFF*SLKRRRKKI*VWLSHLKCSF *LFYSHRRYCTGQHASWM*TMRKNQWSDHLGVS GVA*STSGVLFCVSFLCATCFHSLNYQHLCGGFS TFSIVLQPGSTFCRSERLIPIM*WDHTRSMLQL YE*QKVHLTLVVQELFLSKQTFQSSMK*RSPSF NSWAEFSGFHII*TCCAAVYSITVSLERKKGIIL PSCPSYFISSILSIYIHVVIPSEFPGFNPKDSV *QQCLGRPGAASVPFEGSESLLRLRKIKIIWQK VRDGNSSLG**KMGPVLLTFFYFGSWCVSFGIHF LLA*IGHAFR*VLFFFGEHEVFLTKLNELERIL F*DICS*CKVFL*SSMTVLTYLHRIFFLIFEET SLESVFIGAS*KSLLCSWWERERDSHTRAVSRAQ LQAE*MPSEFSLEAFCCSASGRFQNLLLKPGVV VRAPRHSDSGG*GRRIT*AQSWRPAWAT*RGLS P*KINK*IINK*INKNLVLDYCAVCCPFVGMGLG SE*ACA*MAESFGGVCLFVCFLRGGGVSSEPFW LKNNVHNFYYEI*KVKYFFFSGLPS**TKSI** NSTVEKI*K*ISYGPKGWIVTVHNLS*YMLELES LVILLCSEF*N*KCACMSKDYAELFSLLTM*TF APHEWDFIIWK*A*GCVY*SHVLKVKVDLNIYK AVF*L*LEIIYYAYRTSCILSWNL*INGPCRIQG *GKLVTTCFKSTYYKLLLA*LKLFENLN*TGSH CQETSSKLDIYV*EGNVEEKVRHETKTAGRVGS DCT*FLDQSFI*E*IKRRTTCEPT*EGLARK*QL LLQNTVPSK*FSV*IACNFM*P*SVTCMCMTCV *NV*S*DSAGRGLALSLWWISGPAEVTGLM*LR FAASDPCVCIKWPHR*NRINLSLSFLSYFAALLV LTASFFCFLVSFFLLK*KHEILN

Frame 1

GSSRRSRLSSRGCSSCRLHTASAAARRARACGA AAGRAAPAGTPQRAAEEAPGGGAGPRGGGRRRP PGDQLRASASPPPPQPFSRPLLPHSRPAPRLCAR RWCSPLAAEGGAGHLSPVSELLPTPGGETPPSA RRLLRLPAGGEASAPPAP*VNRVSVRQELL*WF MMMPIRSGCQLVAQLDSAEFISITIQATTHSEWW AGRFRTIRS**TVPFLKG*STIKLHRPSTSGEM LDRCMVSTLAAKRMPMSSQVP*CMP*KC*IHRK QGQHCLDKTHNYLLKFKMAHPKKNWKFKEDNYKN SNGKRSWSGKGWSEKEWKEKGWRERG*KGKGWR GSDWNKNSWRERDKNGNGRNAWSGRNAWSGRNA WSGRNAWIGRGKKDKNERGWRDWNGRGKKGSDKS S*KGNSWNGRESAEYQVLLPLPLLRLL*TLCWE TLLLLSQACRQPLSRPRLHPNRALSWDHLHLHL LHHSHQGLHRLQ*PSLLPQGPLHLLHSHPPGLHR PLLPLLSLIKYPLLLHHLLPHPSLHLDSFWHPC QKTIAL*LDLQLQLPEQNLGKCHGWRIPLSQVE GMLLV*TPPHLKQIQAVEMDPFL*GVVV*WKK*V PCWPGGEELLKRDQQ*KQNKKRTKVKIQSL*LL RPLQQVHLNQQENLGKEQIQ*MAASHLLSPDGI LQGKIRLFLTTGPMIHYTDQNPHPYHSPVPMESR RKDLTMTG*SRTF*MK*EKN*QS*KKSSLMQSG RN*ASQILHRGTD*GEIGL*SGGKISYKQQLFT TANPYIYEL*EENGDKQKEGKTNLL*KPSDIMTL VISSFPLRLLLFSGLYNRMEENHLRVPVTVMQK ILKPIRQDHHALKYFHIKIKSHIFHNTLLK*RG ERLRKFFCRECW*RIEQVCYCIVMFLSGLFFLSC LIFHE*LRSALCKLRS*YVEQMEL*VLSKGNIY KKVSEKCFFSLRNFRMIGSFSS*PSCNFVD*NI KFVQNLKI*MPS*IVTMLYQIYDFYITQTSGQM* TLYCRFTVGFQPFLDLCMWTFL*CNYNHHKVSF FNCRQ*CMSH*YVVAFSRPSPRENIL*SIGEWE EGEE*FFI*S*FLHYLFLSYLHE*IMRNIL*L*L VNMLQNQVLNLLHHVFSYLYFNQ*FQWSET*F* ASHNILTVELKSLITEFGSYYYLGTPAVTQVFR YVFLNEAAFEFCYVEMQEITMMAAIKVTEIIR*R KTNEEFCSFLLISKVRLGWWEEGRWEEGIRHSA CHSACVCSRARAVYMEATPFSFL*NW*G*NRGE ILHVGMIAFWKI*ETLQALHLDLCLSCYVPYLL* TLIIRSFTKTLK*FTFICFLDFVHLSP*SKAC* *CSFLNAANLQPLPLQRSLDEGFFFSLSK*FLF L*KFHF*IKL*WMSYHNSSIHFFFLSDIHCHAVV VKTSKMQQAY*VLFSKRNRRHFHLYYCTFGYAN TLII*TVMSPINLVSNLF*FCWVS*IVCSR*ST GYKWSKLR*ETKIKC*ILKETGFMH*TFCALV*Y *HDVCVN*QKKKKKKTSVESCYISHHPRLLNVL SKKSE*IIIYICYHT*QLCHY*RFQ*LKWETEA *VIYLIKTTFLGTTLL*WFLCSCTLDVLS*VQFR GSFLMTGRHCFPQHCDLTCDKSVLSTM*MAHKS IANKLNVQILVLVLKSLQNSHHDLKVCLKICKH QVSIKTEDETLMNVEFSCF*VYFLFRIFSFLLFL P*LFRLNLFHLSFLHANFVCAIEIKLQYIYVAC L*HLDNLLK*FVLK*VILDVKNTF*SPRLYYLK VYMSRHYSLQIS*KS*ILSNVYKRNM**CVYFLF EITVGCSLFLFSLCPP*HSNFLL*SR**LSV*F LFHFVLQHVQVLKTHSCS*NYPLCSLHGKGHCV VKGIIE**ILSIAKYV*CLYMMLIS*NLHISSST FSLL*SINFEFHFIILMSSLEIQKYNPCIFSLT RPKFSPSPLHSPLHFSWTACSQYSLTFAAITEL QL*NFQLFFFFFFCSSLSHVLASLHM*VSIFVYK LKVTCHSKMS*VT**SFKFT*LQLLCLL*IYIY FQCHCEELAF*F*VVLPYEAQCAKVCYKVSLIP VWPL*FYNTITL*ILPIISSVKVTI*SKHRKGTL QELLIPLCSYHKIHFPEDIYSHSLPNSKPFSGS TTFVFNRKMSSYLYISPKL*GMRKGS*YIEITD V*YLCLFTKSHLIFLKSKLDIQVFIRNLHDSEGM KLM*VALAM*RHSRGQLLKEEFSFEDL*I*LSS *SQ*PLKKVRL*KPRTVGGL*CRFFCSQHQKLW IIWCVPLYVISR*FLRHQDFLKYQYWKDETFKLK PKID*KEK*NINAVNLGWLQILTININKWSSRI NYLWNTNGQVT*E*NLLVRRHI*QLLKN*LNLS F*IVFFIK*QKHCKRINDCHNDLGCCKNVCHIYW LFLLKSEGIDTSEN*EREIGLSPLQILCDAHNL LNGSVSII*ST**ALSICRLTCRKNQR*SPN*V FEPKNHSH*AAPPFCEAC*ILIKSREQGP*TLLV *DTGILGRGRKLGAPVGG*E*KEYTI*VVLFFF LSF*RHIIPSS*DI*IAR*TGQRREDCLRPEVL RSAWVTGRLISTKKFKNLGQAWWCTPVIPATQET EAGGSPEPREDAAAVSRYHATVLQPG*QSENLS LKKKKKNSKRI*LFIEIIRKAYIFH*RAQFVRL HLFRKSSIYK*QPIVYHVNLI*LFPSIPRKISSA VDDNSKSIKK*LIKEMDDVIGWFGWVLVNSYSS KKA*KIEN*IVGTLNSIGKSTQKKKSTLASV*I ES*FSHQVQKFPSKSIETERKGSWLTLKIHIVAT I*ERYITERF*KFGLLSA*QSML*SHL*NLFSF FLFLLFFFLKIKGILKINVSWPGMVAHACNPST LGG*GGQIT*GQEFETSLANMMKPHLY*KYKKIG WA*WWAPVIPALREAETEESLESRRWRLQ*AKT APLYSSLGDRARFHL*INKCFSTCFM*EIPAFH YYYQLISGVTWLVLLTEALGILNMEFPSTH*SSL RFVHPWWQASLTMDSQTPFDCRKS*GHPSASGW ASQ*V*GDEFELAVG*FRNSAIAHGWLVKDVDF AT*ISRRRIAYSLSEESNWEGLDIEKKALLKSR* HFLSSLLLEGWEVQA*VRTLQFGVLPRGTLGLI ILSFNCKKKFLTECCSVTQVGVQWCDLGSLQLP PPGFKGIFLPQPPK*LGLQARATMPD*FLYF**R WGFTMLPRLVLNS*AQVICPPRPSIAEVFEGRI FDPHIKCPCF*KKTW*KLLLSPCLCHLVGLDFP FSVFLPPSVSLSLSFFVCGVVGRSLDWD*LYQFS GCGASQSFSLSLLPLKLSSFFKFFLFCFYFFLA TIQARIDKAFYYYCYYYYFETVSLCHPGWSAVV *FQLTATSASRVQAILLPQPP**LGLQACATTPG *FLYF**RQGFTVLARLVSNS*PQVIHPPWPPK VLGLQA*ATVPIPDKVEF*ISSFTVFSAATGWF ILFF*SFLVYSSFDL*REGEKRSEFGSPILSAAF SCFIVIDAIALDSMHPGCKQCGKINGVTILGSV VLHKAPVVCCSVSVSSAPRAFTV*ITSISVVAS VHSPLCFNLEAHSAVQKD*FQSCNGTTRDPCSNY MNSRRSI*LL*FKSCF*VNRLSRAR*SEEALLS IPGQNSVVFISSEPAVLLFILSLSALKGKKE*S YPPALLILYLPSYPSISM*SFLPSSLVLIQKTLF NSNVLADQVPLPCHLRALSLCFVLGR*R*FGRK SEMEIAVWDDKRWVLFC*HSFTLVLGACPLGFI SC*HE*DMLFVRCFSFLENMKCF*QN*MS*KEFY FETSVVDAKYFCNPQ*QYLHICIEFFF*FLRKP LWSLYL*EHPESPYYVAGGSERGTATLVL*AEH NFRQSECLLSSHWKLSVAQPLADFRTFYLSQVWW CVLLGTATRGAEAEGSLEPKVGGQPGQHSEACL LKK*INK**INK*IKTLSLTIVLSAAPL*GWGW GQNKHVHEWRKALVVFVCLFVF*EVGESAVNLSG *RTTYIISIMRFRRLNTFFFQAYQVDRPKVYSR TAQ*KKFKSEFLMVQKDG*SQSITFHNICWNWN LLSSCFALNFRTRSVHVCQKIMQSYFLC*QCKHL HPMNGTL*SGSEPKVAYTEVMF*KLRLT*TYTR LYFNCN*KSFTMHTEPHVSYHGICELMGLAEFK GKGNW*QLVLNQHTISSCLLDSSCLKI*IKQDLI VRKHLLSLTSTFKKGTWKRR*DMKLKQLGG*DQ TAPDFWTKVSYRNK*KGGPLVSQPRKDLPESSS SCCKIQCLQNDSLCELHAISCNHKV*PVCA*HVS RMCKVRIQQEGAWPCHCGGSVDLLKSLDSCDLG LQHQTPVFALSGHIVEIGSISPSAFFPTLQLCW F*LLHSSASWYPFFF*NKNMKYLI

Frame 2

VPRGDPDSPPAAAAAAGCTRPRRRRGERGPVER RPGARPRRAPLRGRPRKLREEEQDHEEVGGGGR LGTSSAPRPLRPLPSLSLALFSHTPGRRLGFVR GDGVAPWPPKEEPDTCLPSPSCSPPLEERPPPRL GAFCVSRLVGKPLRRRHHE*TEYLSGKSCCDGL **CQ*EVGASWWLNWIQQSSYLSPYRQQHIQSG GQEDSGPSGRDKLCHS*RVEVQSSYTDLPPVARC *TGVWSQLWQQRGCQCLRKCHDACLRSVKFTGN RANIA*TKLTTTCSSSKWPIPRRIGNSKKTTTR TATAKGAGAGKAGARKNGKRKVGEREVRKGKAGE GATGTRTAGERETRTGTAGTPGAAGTPGAAGTP GAAGTPGSGEARKTRTREAGETGTGEARKGATR AVRKGTAGMGERAQNIKCCCPCLC*DSSKLCAGR LFCF*ARLAGSLSAGRDSIPTGHCLGTTCTSTS STTPTRACTGFSSPPSSPRAPSTSSTPIHRAST APSSPSSP*SSTPSSSTTSCPTPPCIWILFGIHV RRQSPFNWTCSCNCRSKT*ESVTDGGYLFPKWR ECYWCELRLI*NRYRPWKWTPSFRG*WFNGRNE CPAGQEEKNC*KGINNRNRTKRGQR*RFRACNF* GLFNKYT*TNKKTLGKNKYNEWQQVTCYLQTGF SKEKSDCF*QQVL*FITQTKIHTLITAQCQWSP DGRT*L*QAEAGHFR*NEKRINKAKRRAH*CNQA GTEQVKYCIEEQTKER*DFNLEEKYPTNNNCSQ QQTPTFMSCKKKMETNRRREKPTYSESLQTL*L W**ALSLSVCCFFLAFTTEWKRII*EFL*QLCRK Y*NPSGKITTH*NIFISR*SRTFSTIHC*NKEE KGLGSFFAESAGKELSKFAIVL*CFSQVCSSYH V*YSMNN*DQPYVS*DHNMWNKWNCKCFQRVIFI RKCPKNVSSA*EILE**EVSRVSLHAIL*IKT* NLSRT*RFRCLPKLLQCFTKSMTST*HKPVVKC KHYIVDLL*VFNLF*IYACGHFYNVITITTRLAF LIADSNACHTNM*WPFQGLVPGKTFCRV*GSGR KGRNNFLFKVDFCTIFFSVTCMNK**EIFCDFN W*ICYKTKYLIFYIMSSAICILTSNFNGLKHDSE LHIIS*LWNSKV*SLNLAVIIT*VPPLLHRCLD TCS*MKLLLNFVMLKCKK*Q*WQQLRSQKSLGK GKPMRSSAVFF**VK*DLGGGKKEGGKKELDTLP ATLRVCALAHVLSIWKPLPFLSFETGKVKIGEK SYMLE**LFGKFKKLSRLSILIYA*VVMCHICF EL*LSEVLLKL*NNSLSSAF*ILYISVHKAKLVD SVVF*TLQICSLYHYKEVWMRDFFFLCQNSSCF CRNFIFRLNCDG*AIIIQVYISFFYQIFIVMQ* **KHQRCSKLIKYYFLKEIGGIFIFIIVLLVMQT L**YKQLCPL*IWSATSFDFVG*VK*SVVGRVL GTSGPN*DKRLK*NAKS*KKLGLCTKRFVPWSN INMMYV*TDKKKKKKKPVLNHAIFPIIPDC*MFF PRSLNELLYTFAIIHDSCVIIRDFSN*NGKQKP KLFTLSKPRSLEPHYYDGFCALVRWMS*AEYSL GDPF**QEGTAFLNTVI*PVTSLYYPLCKWLTSQ LQTN*MYKS*CWC*NLFRIVIMI*KFV*KFASI KCQSKLKMKH**MLNSHAFRCTSFLEFSVFCYF YRNYFV*ICFI*VSYTLTSFVRLK*NCSIYMLLV CDT*IIF*NNLF*SKLYWM*KTPFKVQDFTT*K FTCHVTILYRFHRSREY*VMYTKEICDDVSTFC LK*LLGVPSSYFLSAHLDTVTSSYSQDDD*VFNF YSILFCNTFRYLKLIHAVRIILYVVCMVKDIVW *RALLSNEF*V*QNMYSVYT*C*FLKTYI*AVV LFLYYKVLILSSIL*F*CLH*KYKNTILVFFL*P DPNFPLPPSILLSTSRGPRVPNIH*HLQPLQSY SCKIFSCFFFFFFALACLMFLLLFICKSVFLST N*KSLVIQK*VK*HDNLLNLPSYNFYVSCKFIYT FSAIVKNWPFNSK*YYPMKHSVQRYATRSL*FL CGHYNFITPLPFKFYRL*AA*K*LYKANIAKEL CRSS*FLYVAIIKFTFLKTFTLIHFQTPNLFLVA PLLFLIER*VHICTSLQSSKE*EKDPSILKLLM FNTSAFSLKAI*YF*SQNLTYRYL*GISMTLKE *N*CR*LWLCKDIVEDNYLKKSFLLRICRFD*AA EVSNPSRKSVYRSQELLEVCDAGFSVPNIKSCG LFGVFPFMLSLDNF*DIKIF*NINTGKMKPSN* NLKLIRKKSKILMQ*I*DGYRYSPST*INGVLG* IICGILMVKSHKSKIFW*GDTFDNC*RIN*ICL SK*FSL*SNRNIVKG*MTVIMT*DVVRMSATFI GYFC*NLKESIHLKIEKGK*DCPRYRYSVMHTTF *TEVLVSFKAHSRP*VFAD*HAEKIKDEAPIKC LNQRITVTELHPRSVKHVKYS*RAESRARRRFW CRTQEF*AEGEN*GPQLVAESKKNIPFE*CCSFS SVFKDI*FLVVRTSK*LGKLVRGGRIA*GQKF* DQPG*QGDSFLQKNLKI*ARHGGAHL*SQLLRR LKREDHLSPGRTRLQ*AVIMPLYSSLGDRARTCL *KKKKKILREYSFS*KLLEKLTYFIREPSLLDY IYSVKVLYTNDNP*FIM*I*FNCSLQFQERFLQ Q*MTILKA*RNN**RRWMML*VGLVGF**IVILL RRLRKSRIE*LVL*IP*EKALRRKSLHWLVFRL RVNFPIKSKSFHPSL*KLREKVLGLHLKYTLLQ PYKRDTLQNAFKNLVS*APNSPCFSHICETSFLF FFFFYFFF*RLKAF*K*MFHGRAWWLTPVIPAL WEAEVGRSPEVRSLRPAWPT**NPISTKNTKKL AGHSGGHL*SQLFGRLRQKSRLNPGGGGCSELRP RHCTPAWATERDSISK*INVFQRVLCEKYQLFI ITTS*SQVSLGWFC*PRHWAF*IWSFPPPIDQV *GLSILGGRLA*PWIHKPHLIVVSHKATPVPVVG HHSESEVMNLS*L*ASSATQQ*PMDGW*KTLTL PLKFPGEE*LIVYLRKVIGKA*ILRRKPC*NLG SISFLLYY*RDGRFRPESGLYNLVSFPEVLWA*S F*VSIAKKNF*RSVALSLRLECSGAISAHCNFP PLGSKGFSCLSLPSSWDYRRVPPCPTNFCIFSR DGVSPCCPGWS*TPELR*SARLGLQLQKFLKGEY LILT*NVLVSERKHGKNCY*VHVFATLLDLISL SLCSSRPQSLSVCPFLCVELWAGHWTGTDFTSF QAVGLVSHSL*AFYL*S*VLFLNSFCFVFIFSLP LYKQG*IKLFIIIVIIIISRQSRSVIQAGVQWC DFSSLQPLPPGFKRFSYLSLLSSWDYRHAPPHP ANFCIFSRDRVSPYWPGWSRTPDLR*STHLGLPK CWDYRHKRPCPSPIKLSSEFPLSLYSRQLLVGL FFFFNLFWFILLLIFEEKEKKDLSLALPS*VQL LVVL*S*TLLHWTACILDVNNAEKSME*PSWGQW CCIKHQWCAVLCQFPLRHVLSQFELPASLWWLQ YILHCASTWKHILPFRKTDSNHVMGPHEIHAPI I*IAEGPFDSCSSRAVSK*TDFPELDEVKKPFFQ FLGRIQWFSYHLNLLCCCLFYHCQP*KEKRNNL TLLPFLFYIFHLIHLYPCSHSFRVPWF*SKRLC LTAMSWQTRCRFRAI*GL*VFASS*EDKDNLAES QRWK*QFGMIKDGSCFADILLLWFLVRVLWDSF LASMNRTCFSLGAFLFWRT*SVSNKTE*ARKNS ILRHL*LMQSISVILNDSTYIFA*NFFFNF*GNL SGVCIYRSILKVPIM*LVGAREGQPHSCCEQST TSGRVNAF*VLIGSFLLLSLWQISEPST*ARCG GACS*AQRLGGLRQKDHLSPKLEASLGNIARPVS LKNK*INNK*INK*KPCP*LLCCLLPLCRDGVG VRISMCMNGGKLWWCLFVCLFFERWGSQQ*TFL VKEQRT*FLL*DLEG*ILFFFRPTKLIDQKYIVE QHSRKNLKVNFLWSKRMDSHSP*PFIIYAGIGI SCHLALL*ILELEVCMYVKRLCRAIFFANNVNI CTP*MGLYNLEVSLRLRILKSCFKS*G*LKHIQG CILIVTRNHLLCIQNLMYLIMEFVN*WALPNSR VRETGNNLF*INIL*APACLTQVV*KSELNRIS LSGNIF*A*HLRLRRERGREGET*N*NSWEGRIR LHLIFGPKFHIGINKKEDHL*ANLGRTCQKVAA PAAKYSAFKMILCVNCMQFHVTIKCNLYVHDMC LECVKLGFSRKGPGPVTVVDQWTC*SHWTHVT*V CSIRPLCLH*VATSLKSDQSLPQLSFLLCSFAG FNCFILLLLGILFSFEIKT*NT*F