Sequences - Rnomics 📊 Palace

        ☰
    
        Rnomics 📊 Palace
    
                       Back to Rnomics Platform
            
                       Open Session

1 warning:

Access restricted to public data.
Please sign in at Rnomics Platform to access your data.

Navigation

Home

Sequences

Sequence NM_182740

ATGAGTGCAGTGGGCTTGGTACTCCTGGTGCTTGCTCTGAGGCTTAGGGCCACCACTGTTAAGCCAGAGGAAGGCAGCTTTTGCTCTAACAGCCAGGTGG CCTTCAGAGATGCTTGCTATGAATTTGTGCCACTCGGACGCACCTTCCGTGATGCCCAGAGCTGGTGCGAGGGGCAAGGAGGCCATTTGGTCTTCATTCA GGACGAAGGCACCCAGTGGTTTCTGCAGAAGCACATCTCCCAGGACAGGGAATGGTGGATTGGACTCACGTGGAACTTGGCACGGAATGGAACCACGGAG GGGCCGGGGACTTGGTTGGACACCTCCAATGTGACCTACAGCAACTGGCATGGAGGGCAGGCCGCCGCTGCCCCTGACACCTGCGGCCACATCGGGAGAG GCCCTTCCTCTGAGTGGGTGACCTCGGACTGCGCCCAGACCTTCGCCTTCATGTGCGAGTTCCGGGTTGGCCAGAGCCTGGCCTGCGAGGGACTCAATGC CACCGTGCACTGTGGCTTGGGGCAGGTCATCCAGGTCCAGGATGCCGTCTACGGGCGCCAGAATCCCCATTTCTGCACCCAGGATGCCGGGCGTCCTTCA GATCTGGAGCAGGGATGCAGCTGGGCCAACGTCAAGGAGGAGGTGGCAGGCCAGTGCCAGGAGCTACAGTCATGCCAGGTGGCAGCAGATGAGACCTACT TTGGAAACCTGTGTCCGACTCAGGGCAGTTACCTGTGGGTGCAGTACCAGTGCCGGGAAGCCCTGCAGCTGATGGTGTCCAGTGAGAGTTTCATCTTTGA CAATGTCACCATCTCCCTGACGTGGCTCCTCTCACCCTACATAGGAAACCTGTCCTGTATAATTAGTACAGGAGACAGCCACACTTTTGATCCCTACAAC CCGCCGAGTGTGTCCAGCAATGTGACCCACCAGTTCACATCTCCTGGGGAATTCACCGTGTTTGCTGAATGCACAACCAGTGAGTGGCATGTGACAGCTC AGAGGCAGGTGACCGTGCGAGACAAGATGGAGACGCTCAGTGTGACTGCATGCTCCGGCCTGTCCCAGTCAGGAGCCGGCCCTCTCTGCCAGGCTGTCTT TGGGGATCCTCTGTGGATTCAGGTGGAGCTTGATGGAGGAACAGGAGTGACTTACACTGTGCTTTTGGGTGACATAACCCTGGCCGAGTCCACCACCCAA AAGGGCTCGCTACCGTACAATCTGATCCTGGACAGAGAAACCCAGAAACTGATGGGCCCTGGGAGGCACCGCCTGGAGATCCAAGCCACCGGCAACACCA CCACCTCTACAATCTCCAGAAACATTACAGTCCACTTGGTGGAGCTGCTGTCAGGGCTGCAGGCCTCCTGGGCTTCTGACCATTTGGAGCTTGGACAGGA CCTATTGATCACCATCTCATTGGCTCAGGGCACCCCGGAAGAGCTGACCTTTGAGGTGGCTGGACTCAATGCAACCTTCTCCCACGAGCAAGTGAGCTTT GGAGAGCCATTTGGGATTTGCCGCCTGGCTGTTCCGGTTGAAGGCACCTTTCTGGTCACCATGCTGGTGAGGAATGCCTTCTCCAACCTGAGTTTGGAAA TCGGGAACATCACTATCACAGCCCCTTCCGGTCTCCAAGAACCATCTGGGATGAATGCTGAAGGAAAGAGTAAAGATAAAGGCGATATGGAGGTGTACAT CCAACCTGGTCCATATGTGGATCCTTTCACGACAGTGACCCTGGGCTGGCCAGACAATGACAAGGAGTTACGCTTCCAATGGTCATGTGGGTCTTGCTGG GCTCTGTGGAGCAGCTGTGTTGAGAGGCAGCTGCTTCGCACAGACCAGAGGGAGCTGGTGGTTCCAGCATCCTGCCTGCCGCCGCCTGACTCTGCTGTCA CCCTGCGCCTGGCTGTTCTGAGAGGCCAAGAGCTGGAGAACAGGGCAGAGCAGTGCCTCTACGTGTCTGCGCCCTGGGAACTCAGGCCTCGAGTCAGCTG TGAGAGGAACTGCAGGCCAGTTAATGCCAGCAAAGACATTCTGCTCAGGGTCACCATGGGGGAGGACTCTCCAGTGGCTATGTTCAGCTGGTATTTGGAC AACACCCCAACAGAGCAGGCTGAGCCCCTCCTGGATGCCTGCAGACTCAGAGGATTTTGGCCAAGGTCCTTAACCCTCCTCCAGAGCAACACCTCCACGT TGCTGTTGAACAGCTCGTTTCTGCAGTCCCGGGGAGAGGTCATCCGAATCAGAGCCACAGCACTGACCAGGCATGCCTATGGGGAGGACACCTATGTGAT CAGCACTGTGCCTCCCCGTGAGGTGCCTGCCTGCACTATTGCCCCAGAGGAGGGCACCGTTCTGACGAGCTTTGCCATCTTCTGCAACGCCTCCACAGCC CTGGGACCCCTGGAGTTCTGCTTCTGTCTGGAATCAGGTTCCTGCCTACACTGTGGCCCTGAACCTGCCCTCCCATCAGTGTATCTGCCACTTGGAGAGG AGAACAATGACTTTGTGCTGACAGTAGTTATTTCTGCCACCAATCGTGCAGGGGACACGCAGCAGACCCAGGCCATGGCTAAGGTGGCACTCGGAGACAC ATGTGTTGAGGATGTAGCATTCCAGGCTGCCGTGTCAGAGAAAATCCCCACAGCTCTGCAAGGCGAGGGTGGCCCCGAGCAGCTCCTCCAGCTGGCCAAG GCTGTGTCCTCCATGCTGAACCAAGAGCATGAAAGCCAGGGCTCAGGACAGTCACTGAGCATAGACGTCAGACAGAAGGTCAGAGAGCATGTGCTGGGAT CACTGTCTGCAGTCACCACCGGCTTGGAGGACGTGCAGAGGGTGCAGGAGCTGGCCGAGGTGCTGAGAGAGGTGACCTGCCGGAGTAAGGAACTCACACC CTCGGCCCAGTGGGAGGCCAGCTTGGCTCTACAGCATGCCAGTGAGGCCCTGTTGACAGTGAGTGCCAAGGCCCGCCCTGAGGACCAGAGGCGCCAGGCA GCCACCAGGGACCTGTTTCAGGCTGTGGGCAGTGTGCTGGAAGCTTCCCTGAGCAACAGACCAGAAGAGCCTGCGGAGGCCAGCAGCAGCCAGATTGCCA CAGTGCTGCGGCTGCTTCGAGTCATGGAGCATGTGCAGACCACCCTCCTGCTGGGAAAACTGCCAGGGGGCCTTCCAGCCATGCTGGCCACCCCCTCCAT CTCTGTGTACACAAACAGAATACAACCCTGGAGTTGGCAAGGCTCCTCCCTGCGCCCTGATGCCGCAGACTCTGCAACCTTCATGCTGCCCGCTGCCTCC TCCCTCAGCTCTCTGGAGGGCGGCCAGGAGCCCGTGGATATAAAGATCATGAGTTTCCCAAAGAGCCCCTTTCCAGCCCGAAGCCACTTTGATGTCAGCG GGACTGTCGGTGGCCTCCGTGTGACCAGCCCTAGTGGTCAACTCATACCTGTGAAGAATCTGTCGGAGAATATCGAGATCCTGCTGCCCCGGCATTCACA AAGACACAGCCAGCCGACCGTGTTGAACCTGACCAGTCCTGAAGCTTTGTGGGTGAACGTGACTTCAGGGGAGGCAACCTTGGGGATCCAGCTGCACTGG AGACCAGACATTGCACTCACGCTTAGCCTGGGCTATGGCTACCACCCCAACAAGAGCAGCTACGATGCCCAAACTCACCTCGTACCAATGGTGGCTCCAG ATGAGCTGCCCACGTGGATCCTGAGCCCACAGGACCTGCGTTTTGGAGAAGGGGTCTACTATTTGACTGTGGTCCCTGAGTCTGACCTGGAGCCAGCCCC CGGCAGGGACCTCACGGTTGGCATCACCACCTTCCTGTCTCACTGTGTGTTCTGGGATGAGGTCCAGGAGACTTGGGACGACTCAGGATGCCAGGTGGGG CCTCGGACCAGCCCCTACCAGACACACTGCCTCTGCAACCACCTCACTTTCTTCGGAAGCACGTTCCTGGTGATGTCCAATGCCATCAACATCCACCAGA CTGCTGAGCTCTTTGCCACCTTTGAGGACAACCCTGTGGTCGTGACCACCGTGGGCTGCCTGTGTGTGGTCTACGTGCTGGTGGTGATCTGGGCGAGGAG GAAGGACGCTCAGGATCAGGCCAAGGTGAAGGTCACAGTGCTGGAAGACAATGATCCCTTTGCTCAGTACCACTACCTGGTGACAGTCTACACAGGACAC CGACGAGGGGCAGCCACGTCCTCAAAGGTGACTGTCACCCTGTATGGCCTGGATGGAGAGAGAGAGCCCCACCACCTGGCTGATCCCGACACTCCGGTTT TTGAGCGAGGAGCAGTGGATGCCTTCCTCCTCTCCACCCTGTTCCCCCTGGGAGAACTGCGGAGCCTCCGGCTGTGGCATGACAACTCAGGGGACCGGCC ATCGTGGTATGTGAGCCGGGTGCTGGTCTATGACCTGGTGATGGACCGGAAGTGGTATTTCCTGTGCAACTCCTGGCTATCCATCAATGTTGGAGATTGC GTCCTCGATAAGGTGTTTCCTGTGGCCACGGAGCAGGACAGAAAACAATTCAGCCACCTGTTTTTCATGAAGACTTCCGCGGGCTTCCAGGATGGACACA TCTGGTATTCGATCTTCAGCCGCTGCGCTCGCAGCAGCTTCACCCGCGTCCAGAGGGTGTCCTGCTGCTTCTCCCTGCTGCTGTGCACCATGCTGACCAG CATCATGTTCTGGGGGGTCCCCAAGGACCCAGCTGAGCAAAAGATGGACTTGGGTAAAATTGAATTCACCTGGCAGGAGGTGATGATTGGCCTGGAGAGC TCCATCCTCATGTTCCCCATCAACCTCCTGATTGTTCAGATCTTTCAGAACACCCGTCCCCGGGTCGCGAAGGAGCAGAACACTGGAAAATGGGACCGGG GGTCCCCCAACCTGACTCCCTCCCCACAGCCCATGGAGGACGGCCTTCTGACACCTGAGGCAGTGACCAAGGATGTGTCAAGAATCGTCAGCTCCCTCTT CAAAGCTCTCAAGGTGCCATCCCCCGCCTTGGGCTGGGACTCAGTGAACTTGATGGACATCAACAGTCTCCTCGCCTTGGTGGAAGATGTCATTTATCCA CAGAACACATCAGGGCAGGTGTTCTGGGAGGAAGCCAAAAAGAGAGAGGACCCTGTAACACTCACTTTGGGGTCATCAGAAATGAAAGAGAAATCACAGT GTCCCAAGCCCAAGGCGGCACGGAGTGGCCCCTGGAAGGACAGCGCCTACAGGCAGTGTCTGTACCTTCAGCTGGAACACGTGGAGCAAGAGCTGCGGCT GGTGGGGCCCCGAGGCTTCTCCCAGCCCCACAGCCATGCCTAGGCCCTCAGGCAGCTGCAGACCCTGAAGGGCGGCCTGGGGGTACAGCCGGGCACCTGG GCCCCTGCACATGCCAGGTGCTGGGATTCGCTGCTTTCTTTGCACTGGTCTTGAAGAGAGTGGACGATGAGGAGGATACTGTGGCCCCGCTGCCAGGACA TCTGTTGGGCCCAGACCCCTATGCCTTGTTCCGAGCACGAAGAAACAGCAGCAGGGATGTCTACCAGCCACCTCTCACCGCTGCCATTGAGAAGATGAAA ACCACCCACCTCAAGGAACAGAAAGCATTTGCCCTCATCAGAGAAATCCTGGCATACTTGGGCTTCCTGTGGATGCTACTGCTCGTGGCCTACGGGCAGA GGGACCCCAGCGCCTACCACCTCAACAGACACCTCCAGCACAGCTTCACCAGGGGCTTTTCAGGTGTGCTCGGCTTCCGAGAGTTCTTCAAGTGGGCCAA CACCACCCTCGTGAGTAACCTGTATGGTCACCCCCCAGGCTTTATCACTGATGGGAACTCCAAGCTGGTTGGCAGTGCCCAGATTCGTCAAGTGAGGGTC CAGGAAAGCTCTTGCCCTCTTGCCCAGCAGCCGCAGGCATATCTCAACGGATGCCGTGCACCATATTCCCTGGATGCTGAAGACATGGCAGACTATGGGG AAGGCTGGAATGCCACCACCCTCAGTAATGGCAGTACCAGAGCCAGGACCAACGTCAAGGGTATCCCATCTGGGGCAAACTCACTGTGTACCGGGGAGGA GGCTACGTGGTCCCCTTGGGGACTGATCGCCAAAGCACGTCAAGAATTCTCCGCTATCTCTTTGACAACACCTGGCTGGACGCCCTGACCAGAGCTGTGT TTGTGGAGTCCACTGTCTACAACGCCAACGTCAACCTGTTCTGCATTGTCACGCTGACGCTAGAGACCAGCGCTCTGGGCACCTTTTTTACGCACGCGGC CCTGCAGAGCCTCCGCCTGTACCCCTTCACCGACGGCTGGCACCCCTTCGTGGTAGCGGCAGAGCTCATCTACTTCCTCTTCCTCCTCTACTACATGGTG GTGCAGGGCAAGCGCATGAGTAAAGAGACGTGGGGCTATTTCTGCAGCAAGTGGAACCTTCTGGAGCTGGCCATCATCCTGGCCAGCTGGAGCGCCCTGG CGGTGTTTGTGAAGAGGGCTGTCCTGGCCGAAAGGGACCTCCAGCGCTGCCGGAACCACAGGGAGGAAGGCATCAGCTTCAGTGAGACAGCAGCAGCCGA TGCCGCCCTTGGCTACATCATTGCCTTCCTGGTACTCCTGTCCACAGTGAAGCTTTGGCATCTGCTCAGGTTGAATCCCAAAATGAACATGATCACGGCA GCCCTACGCCGTGCCTGGGGCGACATTTCAGGCTTTATGATTGTCATCCTTACCATGCTCCTGGCTTACTCCATCGCGTCAAACTTGATATTTGGTTGGA AACTCCGTTCCTACAAAACCCTCTTTGATGCGGCGGAGACGATGGTCAGCCTTCAGCTGGGAATCTTCAACTACGAGGAGGTCCTGGACTATAGCCCAGT GCTTGGCTCCTTCCTCATTGGATCCTGCATTGTTTTTATGACATTTGTGGTGCTGAACCTGTTTATCTCTGTCATCCTGGTGGCCTTCAGTGAGGAGCAA AAATACTATCAGCTGTCGGAGGAAGGGGAGATCGTAGATTTGCTGCTGATGAAAATACTCAGTTTCCTGGGCATTAAGTCTAAGAGAGAGGAGCCTGGAA GCAGCAGGGAGCAGCCTGGGTCTCTGTCCCAGACTCGCCACTCTCGACCAGCACAAGCTTTGCCCAAGGACTAAGCTGTTCGTCCACACGCCACCATCTA CCAGTGGGGACGCCCAGGGCCTCGGGCGTACGCTTACCAGCGACTCTATAGTCTCTCTAGGTCATAGCTTTCATGTCCATTGAAGAATTACCAAGCCCAG CAAGTAAAAAAAATTACAATAACAGAGATATATGTAAAATTGCCAATACTATGAGAGCTTCTTTGTTCAAATGTATTTCCTCTTATTATAAATAAAACAA ATATTACATGGA

refseq_PKD1L2.F1 (forward primer)
refseq_PKD1L2.R1 (reverse primer)
Single exon skipping

Frame 0

MSAVGLVLLVLALRLRATTVKPEEGSFCSNSQV AFRDACYEFVPLGRTFRDAQSWCEGQGGHLVFIQ DEGTQWFLQKHISQDREWWIGLTWNLARNGTTE GPGTWLDTSNVTYSNWHGGQAAAAPDTCGHIGR GPSSEWVTSDCAQTFAFMCEFRVGQSLACEGLNA TVHCGLGQVIQVQDAVYGRQNPHFCTQDAGRPS DLEQGCSWANVKEEVAGQCQELQSCQVAADETY FGNLCPTQGSYLWVQYQCREALQLMVSSESFIFD NVTISLTWLLSPYIGNLSCIISTGDSHTFDPYN PPSVSSNVTHQFTSPGEFTVFAECTTSEWHVTA QRQVTVRDKMETLSVTACSGLSQSGAGPLCQAVF GDPLWIQVELDGGTGVTYTVLLGDITLAESTTQ KGSLPYNLILDRETQKLMGPGRHRLEIQATGNT TTSTISRNITVHLVELLSGLQASWASDHLELGQD LLITISLAQGTPEELTFEVAGLNATFSHEQVSF GEPFGICRLAVPVEGTFLVTMLVRNAFSNLSLE IGNITITAPSGLQEPSGMNAEGKSKDKGDMEVYI QPGPYVDPFTTVTLGWPDNDKELRFQWSCGSCW ALWSSCVERQLLRTDQRELVVPASCLPPPDSAV TLRLAVLRGQELENRAEQCLYVSAPWELRPRVSC ERNCRPVNASKDILLRVTMGEDSPVAMFSWYLD NTPTEQAEPLLDACRLRGFWPRSLTLLQSNTST LLLNSSFLQSRGEVIRIRATALTRHAYGEDTYVI STVPPREVPACTIAPEEGTVLTSFAIFCNASTA LGPLEFCFCLESGSCLHCGPEPALPSVYLPLGE ENNDFVLTVVISATNRAGDTQQTQAMAKVALGDT CVEDVAFQAAVSEKIPTALQGEGGPEQLLQLAK AVSSMLNQEHESQGSGQSLSIDVRQKVREHVLG SLSAVTTGLEDVQRVQELAEVLREVTCRSKELTP SAQWEASLALQHASEALLTVSAKARPEDQRRQA ATRDLFQAVGSVLEASLSNRPEEPAEASSSQIA TVLRLLRVMEHVQTTLLLGKLPGGLPAMLATPSI SVYTNRIQPWSWQGSSLRPDAADSATFMLPAAS SLSSLEGGQEPVDIKIMSFPKSPFPARSHFDVS GTVGGLRVTSPSGQLIPVKNLSENIEILLPRHSQ RHSQPTVLNLTSPEALWVNVTSGEATLGIQLHW RPDIALTLSLGYGYHPNKSSYDAQTHLVPMVAP DELPTWILSPQDLRFGEGVYYLTVVPESDLEPAP GRDLTVGITTFLSHCVFWDEVQETWDDSGCQVG PRTSPYQTHCLCNHLTFFGSTFLVMSNAINIHQ TAELFATFEDNPVVVTTVGCLCVVYVLVVIWARR KDAQDQAKVKVTVLEDNDPFAQYHYLVTVYTGH RRGAATSSKVTVTLYGLDGEREPHHLADPDTPV FERGAVDAFLLSTLFPLGELRSLRLWHDNSGDRP SWYVSRVLVYDLVMDRKWYFLCNSWLSINVGDC VLDKVFPVATEQDRKQFSHLFFMKTSAGFQDGH IWYSIFSRCARSSFTRVQRVSCCFSLLLCTMLTS IMFWGVPKDPAEQKMDLGKIEFTWQEVMIGLES SILMFPINLLIVQIFQNTRPRVAKEQNTGKWDR GSPNLTPSPQPMEDGLLTPEAVTKDVSRIVSSLF KALKVPSPALGWDSVNLMDINSLLALVEDVIYP QNTSGQVFWEEAKKREDPVTLTLGSSEMKEKSQ CPKPKAARSGPWKDSAYRQCLYLQLEHVEQELRL VGPRGFSQPHSHA*ALRQLQTLKGGLGVQPGTW APAHARCWDSLLSLHWS*REWTMRRILWPRCQD ICWAQTPMPCSEHEETAAGMSTSHLSPLPLRR*K PPTSRNRKHLPSSEKSWHTWASCGCYCSWPTGR GTPAPTTSTDTSSTASPGAFQVCSASESSSSGP TPPS*VTCMVTPQALSLMGTPSWLAVPRFVK*GS RKALALLPSSRRHISTDAVHHIPWMLKTWQTMG KAGMPPPSVMAVPEPGPTSRVSHLGQTHCVPGR RLRGPLGD*SPKHVKNSPLSL*QHLAGRPDQSCV CGVHCLQRQRQPVLHCHADARDQRSGHLFYARG PAEPPPVPLHRRLAPLRGSGRAHLLPLPPLLHG GAGQAHE*RDVGLFLQQVEPSGAGHHPGQLERPG GVCEEGCPGRKGPPALPEPQGGRHQLQ*DSSSR CRPWLHHCLPGTPVHSEALASAQVESQNEHDHG SPTPCLGRHFRLYDCHPYHAPGLLHRVKLDIWLE TPFLQNPL*CGGDDGQPSAGNLQLRGGPGL*PS AWLLPHWILHCFYDICGAEPVYLCHPGGLQ*GA KILSAVGGRGDRRFAADENTQFPGH*V*ERGAWK QQGAAWVSVPDSPLSTSTSFAQGLSCSSTRHHL PVGTPRASGVRLPATL*SL*VIAFMSIEELPSP ASKKNYNNRDICKIANTMRASLFKCISSYYK*NK YYM

Frame 1

*VQWAWYSWCLL*GLGPPLLSQRKAAFALTARW PSEMLAMNLCHSDAPSVMPRAGARGKEAIWSSF RTKAPSGFCRSTSPRTGNGGLDSRGTWHGMEPRR GRGLGWTPPM*PTATGMEGRPPLPLTPAATSGE ALPLSG*PRTAPRPSPSCASSGLARAWPARDSM PPCTVAWGRSSRSRMPSTGARIPISAPRMPGVLQ IWSRDAAGPTSRRRWQASARSYSHARWQQMRPT LETCVRLRAVTCGCSTSAGKPCS*WCPVRVSSL TMSPSP*RGSSHPT*ETCPV*LVQETATLLIPTT RRVCPAM*PTSSHLLGNSPCLLNAQPVSGM*QL RGR*PCETRWRRSV*LHAPACPSQEPALSARLS LGILCGFRWSLMEEQE*LTLCFWVT*PWPSPPPK RARYRTI*SWTEKPRN*WALGGTAWRSKPPATP PPLQSPETLQSTWWSCCQGCRPPGLLTIWSLDR TY*SPSHWLRAPRKS*PLRWLDSMQPSPTSK*AL ESHLGFAAWLFRLKAPFWSPCW*GMPSPT*VWK SGTSLSQPLPVSKNHLG*MLKERVKIKAIWRCT SNLVHMWILSRQ*PWAGQTMTRSYASNGHVGLAG LCGAAVLRGSCFAQTRGSWWFQHPACRRLTLLS PCAWLF*EAKSWRTGQSSASTCLRPGNSGLESA VRGTAGQLMPAKTFCSGSPWGRTLQWLCSAGIWT TPQQSRLSPSWMPADSEDFGQGP*PSSRATPPR CC*TARFCSPGERSSESEPQH*PGMPMGRTPM* SALCLPVRCLPALLPQRRAPF*RALPSSATPPQP WDPWSSASVWNQVPAYTVALNLPSHQCICHLER RTMTLC*Q*LFLPPIVQGTRSRPRPWLRWHSET HVLRM*HSRLPCQRKSPQLCKARVAPSSSSSWPR LCPPC*TKSMKARAQDSH*A*TSDRRSESMCWD HCLQSPPAWRTCRGCRSWPRC*ER*PAGVRNSH PRPSGRPAWLYSMPVRPC*Q*VPRPALRTRGARQ PPGTCFRLWAVCWKLP*ATDQKSLRRPAAARLP QCCGCFESWSMCRPPSCWENCQGAFQPCWPPPP SLCTQTEYNPGVGKAPPCALMPQTLQPSCCPLPP PSALWRAARSPWI*RS*VSQRAPFQPEATLMSA GLSVASV*PALVVNSYL*RICRRISRSCCPGIH KDTASRPC*T*PVLKLCG*T*LQGRQPWGSSCTG DQTLHSRLAWAMATTPTRAATMPKLTSYQWWLQ MSCPRGS*AHRTCVLEKGSTI*LWSLSLTWSQP PAGTSRLASPPSCLTVCSGMRSRRLGTTQDARWG LGPAPTRHTASATTSLSSEARSW*CPMPSTSTR LLSSLPPLRTTLWS*PPWAACVWSTCWW*SGRG GRTLRIRPR*RSQCWKTMIPLLSTTTW*QSTQDT DEGQPRPQR*LSPCMAWMERESPTTWLIPTLRF LSEEQWMPSSSPPCSPWENCGASGCGMTTQGTG HRGM*AGCWSMTW*WTGSGISCATPGYPSMLEIA SSIRCFLWPRSRTENNSATCFS*RLPRASRMDT SGIRSSAAALAAASPASRGCPAASPCCCAPC*P ASCSGGSPRTQLSKRWTWVKLNSPGRR**LAWRA PSSCSPSTS*LFRSFRTPVPGSRRSRTLENGTG GPPT*LPPHSPWRTAF*HLRQ*PRMCQESSAPS SKLSRCHPPPWAGTQ*T*WTSTVSSPWWKMSFIH RTHQGRCSGRKPKRERTL*HSLWGHQK*KRNHS VPSPRRHGVAPGRTAPTGSVCTFSWNTWSKSCG WWGPEASPSPTAMPRPSGSCRP*RAAWGYSRAPG PLHMPGAGIRCFLCTGLEESGR*GGYCGPAART SVGPRPLCLVPSTKKQQQGCLPATSHRCH*EDE NHPPQGTESICPHQRNPGILGLPVDATARGLRAE GPQRLPPQQTPPAQLHQGLFRCARLPRVLQVGQ HHPRE*PVWSPPRLYH*WELQAGWQCPDSSSEG PGKLLPSCPAAAGISQRMPCTIFPGC*RHGRLWG RLECHHPQ*WQYQSQDQRQGYPIWGKLTVYRGG GYVVPLGTDRQSTSRILRYLFDNTWLDALTRAV FVESTVYNANVNLFCIVTLTLETSALGTFFTHAA LQSLRLYPFTDGWHPFVVAAELIYFLFLLYYMV VQGKRMSKETWGYFCSKWNLLELAIILASWSAL AVFVKRAVLAERDLQRCRNHREEGISFSETAAAD AALGYIIAFLVLLSTVKLWHLLRLNPKMNMITA ALRRAWGDISGFMIVILTMLLAYSIASNLIFGW KLRSYKTLFDAAETMVSLQLGIFNYEEVLDYSPV LGSFLIGSCIVFMTFVVLNLFISVILVAFSEEQ KYYQLSEEGEIVDLLLMKILSFLGIKSKREEPG SSREQPGSLSQTRHSRPAQALPKD*AVRPHATIY QWGRPGPRAYAYQRLYSLSRS*LSCPLKNYQAQ QVKKITITEIYVKLPIL*ELLCSNVFPLIINKT NITW

Frame 2

ECSGLGTPGACSEA*GHHC*ARGRQLLL*QPGG LQRCLL*ICATRTHLP*CPELVRGARRPFGLHS GRRHPVVSAEAHLPGQGMVDWTHVELGTEWNHG GAGDLVGHLQCDLQQLAWRAGRRCP*HLRPHRER PFL*VGDLGLRPDLRLHVRVPGWPEPGLRGTQC HRALWLGAGHPGPGCRLRAPESPFLHPGCRASF RSGAGMQLGQRQGGGGRPVPGATVMPGGSR*DLL WKPVSDSGQLPVGAVPVPGSPAADGVQ*EFHL* QCHHLPDVAPLTLHRKPVLYN*YRRQPHF*SLQ PAECVQQCDPPVHISWGIHRVC*MHNQ*VACDSS EAGDRARQDGDAQCDCMLRPVPVRSRPSLPGCL WGSSVDSGGA*WRNRSDLHCAFG*HNPGRVHHP KGLATVQSDPGQRNPETDGPWEAPPGDPSHRQHH HLYNLQKHYSPLGGAAVRAAGLLGF*PFGAWTG PIDHHLIGSGHPGRADL*GGWTQCNLLPRASEL WRAIWDLPPGCSG*RHLSGHHAGEECLLQPEFGN REHHYHSPFRSPRTIWDEC*RKE*R*RRYGGVH PTWSICGSFHDSDPGLARQ*QGVTLPMVMWVLL GSVEQLC*EAAASHRPEGAGGSSILPAAA*LCCH PAPGCSERPRAGEQGRAVPLRVCALGTQASSQL *EELQAS*CQQRHSAQGHHGGGLSSGYVQLVFG QHPNRAG*APPGCLQTQRILAKVLNPPPEQHLHV AVEQLVSAVPGRGHPNQSHSTDQACLWGGHLCD QHCASP*GACLHYCPRGGHRSDELCHLLQRLHS PGTPGVLLLSGIRFLPTLWP*TCPPISVSATWRG EQ*LCADSSYFCHQSCRGHAADPGHG*GGTRRH MC*GCSIPGCRVRENPHSSARRGWPRAAPPAGQ GCVLHAEPRA*KPGLRTVTEHRRQTEGQRACAGI TVCSHHRLGGRAEGAGAGRGAERGDLPE*GTHT LGPVGGQLGSTACQ*GPVDSECQGPP*GPEAPG SHQGPVSGCGQCAGSFPEQQTRRACGGQQQPDCH SAAAASSHGACADHPPAGKTARGPSSHAGHPLH LCVHKQNTTLELARLLPAP*CRRLCNLHAARCL LPQLSGGRPGARGYKDHEFPKEPLSSPKPL*CQR DCRWPPCDQP*WSTHTCEESVGEYRDPAAPAFT KTQPADRVEPDQS*SFVGERDFRGGNLGDPAAL ETRHCTHA*PGLWLPPQQEQLRCPNSPRTNGGSR *AAHVDPEPTGPAFWRRGLLFDCGP*V*PGASP RQGPHGWHHHLPVSLCVLG*GPGDLGRLRMPGG ASDQPLPDTLPLQPPHFLRKHVPGDVQCHQHPPD C*ALCHL*GQPCGRDHRGLPVCGLRAGGDLGEE EGRSGSGQGEGHSAGRQ*SLCSVPLPGDSLHRT PTRGSHVLKGDCHPVWPGWRERAPPPG*SRHSGF *ARSSGCLPPLHPVPPGRTAEPPAVA*QLRGPA IVVCEPGAGL*PGDGPEVVFPVQLLAIHQCWRL RPR*GVSCGHGAGQKTIQPPVFHEDFRGLPGWTH LVFDLQPLRSQQLHPRPEGVLLLLPAAVHHADQ HHVLGGPQGPS*AKDGLG*N*IHLAGGDDWPGE LHPHVPHQPPDCSDLSEHPSPGREGAEHWKMGPG VPQPDSLPTAHGGRPSDT*GSDQGCVKNRQLPL QSSQGAIPRLGLGLSELDGHQQSPRLGGRCHLS TEHIRAGVLGGSQKERGPCNTHFGVIRNEREITV SQAQGGTEWPLEGQRLQAVSVPSAGTRGARAAA GGAPRLLPAPQPCLGPQAAADPEGRPGGTAGHL GPCTCQVLGFAAFFALVLKRVDDEEDTVAPLPGH LLGPDPYALFRARRNSSRDVYQPPLTAAIEKMK TTHLKEQKAFALIREILAYLGFLWMLLLVAYGQ RDPSAYHLNRHLQHSFTRGFSGVLGFREFFKWAN TTLVSNLYGHPPGFITDGNSKLVGSAQIRQVRV QESSCPLAQQPQAYLNGCRAPYSLDAEDMADYG EGWNATTLSNGSTRARTNVKGIPSGANSLCTGEE ATWSPWGLIAKARQEFSAISLTTPGWTP*PELC LWSPLSTTPTSTCSALSR*R*RPALWAPFLRTR PCRASACTPSPTAGTPSW*RQSSSTSSSSSTTWW CRASA*VKRRGAISAASGTFWSWPSSWPAGAPW RCL*RGLSWPKGTSSAAGTTGRKASASVRQQQP MPPLATSLPSWYSCPQ*SFGICSG*IPK*T*SRQ PYAVPGATFQAL*LSSLPCSWLTPSRQT*YLVG NSVPTKPSLMRRRRWSAFSWESSTTRRSWTIAQ CLAPSSLDPALFL*HLWC*TCLSLSSWWPSVRSK NTISCRRKGRS*ICC**KYSVSWALSLRERSLE AAGSSLGLCPRLATLDQHKLCPRTKLFVHTPPS TSGDAQGLGRTLTSDSIVSLGHSFHVH*RITKPS K*KKLQ*QRYM*NCQYYESFFVQMYFLLL*IKQ ILHG

Sequence NM_052892

ATGAGTGCAGTGGGCTTGGTACTCCTGGTGCTTGCTCTGAGGCTTAGGGCCACCACTGTTAAGCCAGAGGAAGGCAGCTTTTGCTCTAACAGCCAGGTGG CCTTCAGAGATGCTTGCTATGAATTTGTGCCACTCGGACGCACCTTCCGTGATGCCCAGAGCTGGTGCGAGGGGCAAGGAGGCCATTTGGTCTTCATTCA GGACGAAGGCACCCAGTGGTTTCTGCAGAAGCACATCTCCCAGGACAGGGAATGGTGGATTGGACTCACGTGGAACTTGGCACGGAATGGAACCACGGAG GGGCCGGGGACTTGGTTGGACACCTCCAATGTGACCTACAGCAACTGGCATGGAGGGCAGGCCGCCGCTGCCCCTGACACCTGCGGCCACATCGGGAGAG GCCCTTCCTCTGAGTGGGTGACCTCGGACTGCGCCCAGACCTTCGCCTTCATGTGCGAGTTCCGGGTTGGCCAGAGCCTGGCCTGCGAGGGACTCAATGC CACCGTGCACTGTGGCTTGGGGCAGGTCATCCAGGTCCAGGATGCCGTCTACGGGCGCCAGAATCCCCATTTCTGCACCCAGGATGCCGGGCGTCCTTCA GATCTGGAGCAGGGATGCAGCTGGGCCAACGTCAAGGAGGAGGTGGCAGGCCAGTGCCAGGAGCTACAGTCATGCCAGGTGGCAGCAGATGAGACCTACT TTGGAAACCTGTGTCCGACTCAGGGCAGTTACCTGTGGGTGCAGTACCAGTGCCGGGAAGCCCTGCAGCTGATGGTGTCCAGTGAGAGTTTCATCTTTGA CAATGTCACCATCTCCCTGACGTGGCTCCTCTCACCCTACATAGGAAACCTGTCCTGTATAATTAGTACAGGAGACAGCCACACTTTTGATCCCTACAAC CCGCCGAGTGTGTCCAGCAATGTGACCCACCAGTTCACATCTCCTGGGGAATTCACCGTGTTTGCTGAATGCACAACCAGTGAGTGGCATGTGACAGCTC AGAGGCAGGTGACCGTGCGAGACAAGATGGAGACGCTCAGTGTGACTGCATGCTCCGGCCTGTCCCAGTCAGGAGCCGGCCCTCTCTGCCAGGCTGTCTT TGGGGATCCTCTGTGGATTCAGGTGGAGCTTGATGGAGGAACAGGAGTGACTTACACTGTGCTTTTGGGTGACATAACCCTGGCCGAGTCCACCACCCAA AAGGGCTCGCTACCGTACAATCTGATCCTGGACAGAGAAACCCAGAAACTGATGGGCCCTGGGAGGCACCGCCTGGAGATCCAAGCCACCGGCAACACCA CCACCTCTACAATCTCCAGAAACATTACAGTCCACTTGGTGGAGCTGCTGTCAGGGCTGCAGGCCTCCTGGGCTTCTGACCATTTGGAGCTTGGACAGGA CCTATTGATCACCATCTCATTGGCTCAGGGCACCCCGGAAGAGCTGACCTTTGAGGTGGCTGGACTCAATGCAACCTTCTCCCACGAGCAAGTGAGCTTT GGAGAGCCATTTGGGATTTGCCGCCTGGCTGTTCCGGTTGAAGGCACCTTTCTGGTCACCATGCTGGTGAGGAATGCCTTCTCCAACCTGAGTTTGGAAA TCGGGAACATCACTATCACAGCCCCTTCCGGTCTCCAAGAACCATCTGGGATGAATGCTGAAGGAAAGAGTAAAGATAAAGGCGATATGGAGGTGTACAT CCAACCTGGTCCATATGTGGATCCTTTCACGACAGTGACCCTGGGCTGGCCAGACAATGACAAGGAGTTACGCTTCCAATGGTCATGTGGGTCTTGCTGG GCTCTGTGGAGCAGCTGTGTTGAGAGGCAGCTGCTTCGCACAGACCAGAGGGAGCTGGTGGTTCCAGCATCCTGCCTGCCGCCGCCTGACTCTGCTGTCA CCCTGCGCCTGGCTGTTCTGAGAGGCCAAGAGCTGGAGAACAGGGCAGAGCAGTGCCTCTACGTGTCTGCGCCCTGGGAACTCAGGCCTCGAGTCAGCTG TGAGAGGAACTGCAGGCCAGTTAATGCCAGCAAAGACATTCTGCTCAGGGTCACCATGGGGGAGGACTCTCCAGTGGCTATGTTCAGCTGGTATTTGGAC AACACCCCAACAGAGCAGGCTGAGCCCCTCCTGGATGCCTGCAGACTCAGAGGATTTTGGCCAAGGTCCTTAACCCTCCTCCAGAGCAACACCTCCACGT TGCTGTTGAACAGCTCGTTTCTGCAGTCCCGGGGAGAGGTCATCCGAATCAGAGCCACAGCACTGACCAGGCATGCCTATGGGGAGGACACCTATGTGAT CAGCACTGTGCCTCCCCGTGAGGTGCCTGCCTGCACTATTGCCCCAGAGGAGGGCACCGTTCTGACGAGCTTTGCCATCTTCTGCAACGCCTCCACAGCC CTGGGACCCCTGGAGTTCTGCTTCTGTCTGGAATCAGGTTCCTGCCTACACTGTGGCCCTGAACCTGCCCTCCCATCAGTGTATCTGCCACTTGGAGAGG AGAACAATGACTTTGTGCTGACAGTAGTTATTTCTGCCACCAATCGTGCAGGGGACACGCAGCAGACCCAGGCCATGGCTAAGGTGGCACTCGGAGACAC ATGTGTTGAGGATGTAGCATTCCAGGCTGCCGTGTCAGAGAAAATCCCCACAGCTCTGCAAGGCGAGGGTGGCCCCGAGCAGCTCCTCCAGCTGGCCAAG GCTGTGTCCTCCATGCTGAACCAAGAGCATGAAAGCCAGGGCTCAGGACAGTCACTGAGCATAGACGTCAGACAGAAGGTCAGAGAGCATGTGCTGGGAT CACTGTCTGCAGTCACCACCGGCTTGGAGGACGTGCAGAGGGTGCAGGAGCTGGCCGAGGTGCTGAGAGAGGTGACCTGCCGGAGTAAGGAACTCACACC CTCGGCCCAGTGGGAGGCCAGCTTGGCTCTACAGCATGCCAGTGAGGCCCTGTTGACAGTGAGTGCCAAGGCCCGCCCTGAGGACCAGAGGCGCCAGGCA GCCACCAGGGACCTGTTTCAGGCTGTGGGCAGTGTGCTGGAAGCTTCCCTGAGCAACAGACCAGAAGAGCCTGCGGAGGCCAGCAGCAGCCAGATTGCCA CAGTGCTGCGGCTGCTTCGAGTCATGGAGCATGTGCAGACCACCCTCCTGCTGGGAAAACTGCCAGGGGGCCTTCCAGCCATGCTGGCCACCCCCTCCAT CTCTGTGTACACAAACAGAATACAACCCTGGAGTTGGCAAGGCTCCTCCCTGCGCCCTGATGCCGCAGACTCTGCAACCTTCATGCTGCCCGCTGCCTCC TCCCTCAGCTCTCTGGAGGGCGGCCAGGAGCCCGTGGATATAAAGATCATGAGTTTCCCAAAGAGCCCCTTTCCAGCCCGAAGCCACTTTGATGTCAGCG GGACTGTCGGTGGCCTCCGTGTGACCAGCCCTAGTGGTCAACTCATACCTGTGAAGAATCTGTCGGAGAATATCGAGATCCTGCTGCCCCGGCATTCACA AAGACACAGCCAGCCGACCGTGTTGAACCTGACCAGTCCTGAAGCTTTGTGGGTGAACGTGACTTCAGGGGAGGCAACCTTGGGGATCCAGCTGCACTGG AGACCAGACATTGCACTCACGCTTAGCCTGGGCTATGGCTACCACCCCAACAAGAGCAGCTACGATGCCCAAACTCACCTCGTACCAATGGTGGCTCCAG ATGAGCTGCCCACGTGGATCCTGAGCCCACAGGACCTGCGTTTTGGAGAAGGGGTCTACTATTTGACTGTGGTCCCTGAGTCTGACCTGGAGCCAGCCCC CGGCAGGGACCTCACGGTTGGCATCACCACCTTCCTGTCTCACTGTGTGTTCTGGGATGAGGTCCAGGAGACTTGGGACGACTCAGGATGCCAGGTGGGG CCTCGGACCAGCCCCTACCAGACACACTGCCTCTGCAACCACCTCACTTTCTTCGGAAGCACGTTCCTGGTGATGTCCAATGCCATCAACATCCACCAGA CTGCTGAGCTCTTTGCCACCTTTGAGGACAACCCTGTGGTCGTGACCACCGTGGGCTGCCTGTGTGTGGTCTACGTGCTGGTGGTGATCTGGGCGAGGAG GAAGGACGCTCAGGATCAGGCCAAGGTGAAGGTCACAGTGCTGGAAGACAATGATCCCTTTGCTCAGTACCACTACCTGGTGACAGTCTACACAGGACAC CGACGAGGGGCAGCCACGTCCTCAAAGGTGACTGTCACCCTGTATGGCCTGGATGGAGAGAGAGAGCCCCACCACCTGGCTGATCCCGACACTCCGGTTT TTGAGCGAGGAGCAGTGGATGCCTTCCTCCTCTCCACCCTGTTCCCCCTGGGAGAACTGCGGAGCCTCCGGCTGTGGCATGACAACTCAGGGGACCGGCC ATCGTGGTATGTGAGCCGGGTGCTGGTCTATGACCTGGTGATGGACCGGAAGTGGTATTTCCTGTGCAACTCCTGGCTATCCATCAATGTTGGAGATTGC GTCCTCGATAAGGTGTTTCCTGTGGCCACGGAGCAGGACAGAAAACAATTCAGCCACCTGTTTTTCATGAAGACTTCCGCGGGCTTCCAGGATGGACACA TCTGGTATTCGATCTTCAGCCGCTGCGCTCGCAGCAGCTTCACCCGCGTCCAGAGGGTGTCCTGCTGCTTCTCCCTGCTGCTGTGCACCATGCTGACCAG CATCATGTTCTGGGGGGTCCCCAAGGACCCAGCTGAGCAAAAGATGGACTTGGGTAAAATTGAATTCACCTGGCAGGAGGTGATGATTGGCCTGGAGAGC TCCATCCTCATGTTCCCCATCAACCTCCTGATTGTTCAGATCTTTCAGAACACCCGTCCCCGGGTCGCGAAGGAGCAGAACACTGGAAAATGGGACCGGG GGTCCCCCAACCTGACTCCCTCCCCACAGCCCATGGAGGACGGCCTTCTGACACCTGAGGCAGTGACCAAGGATGTGTCAAGAATCGTCAGCTCCCTCTT CAAAGCTCTCAAGGTGCCATCCCCCGCCTTGGGCTGGGACTCAGTGAACTTGATGGACATCAACAGTCTCCTCGCCTTGGTGGAAGATGTCATTTATCCA CAGAACACATCAGGGCAGGTGTTCTGGGAGGAAGCCAAAAAGAGAGAGGACCCTGTAACACTCACTTTGGGGTCATCAGAAATGAAAGAGAAATCACAGT GTCCCAAGCCCAAGGCGGCACGGAGTGGCCCCTGGAAGGACAGCGCCTACAGGCAGTGTCTGTACCTTCAGCTGGAACACGTGGAGCAAGAGCTGCGGCT GGTGGGGCCCCGAGGCTTCTCCCAGCCCCACAGCCATGCCTAGGCCCTCAGGCAGCTGCAGACCCTGAAGGGCGGCCTGGGGGTACAGCCGGGCACCTGG GCCCCTGCACATGCCAGCGCTCTTCAGGTGAGCAAACCCCCTCAAGGCCTGCCCTGGTGGTGCATCCTGGTGGGCTGGCTCCTGGTAGCGGCCACCAGTG GCGTGGCGGCCTTCTTCACCATGCTCTACGGCCTGCACTACGGGAGGGCCAGCTCCCTCAGGTGGCTCATCTCCATGGCTGTCTCCTTCGTGGAGAGCAT GTTCGTCACCCAGCCCCTGAAGGTGCTGGGATTCGCTGCTTTCTTTGCACTGGTCTTGAAGAGAGTGGACGATGAGGAGGATACTGTGGCCCCGCTGCCA GGACATCTGTTGGGCCCAGACCCCTATGCCTTGTTCCGAGCACGAAGAAACAGCAGCAGGGATGTCTACCAGCCACCTCTCACCGCTGCCATTGAGAAGA TGAAAACCACCCACCTCAAGGAACAGAAAGCATTTGCCCTCATCAGAGAAATCCTGGCATACTTGGGCTTCCTGTGGATGCTACTGCTCGTGGCCTACGG GCAGAGGGACCCCAGCGCCTACCACCTCAACAGACACCTCCAGCACAGCTTCACCAGGGGCTTTTCAGGTGTGCTCGGCTTCCGAGAGTTCTTCAAGTGG GCCAACACCACCCTCGTGAGTAACCTGTATGGTCACCCCCCAGGCTTTATCACTGATGGGAACTCCAAGCTGGTTGGCAGTGCCCAGATTCGTCAAGTGA GGGTCCAGGAAAGCTCTTGCCCTCTTGCCCAGCAGCCGCAGGCATATCTCAACGGATGCCGTGCACCATATTCCCTGGATGCTGAAGACATGGCAGACTA TGGGGAAGGCTGGAATGCCACCACCCTCAGTAATGGCAGTACCAGAGCCAGGACCAACGTCAAGGGTATCCCATCTGGGGCAAACTCACTGTGTACCGGG GAGGAGGCTACGTGGTCCCCTTGGGGACTGATCGCCAAAGCACGTCAAGAATTCTCCGCTATCTCTTTGACAACACCTGGCTGGACGCCCTGACCAGAGC TGTGTTTGTGGAGTCCACTGTCTACAACGCCAACGTCAACCTGTTCTGCATTGTCACGCTGACGCTAGAGACCAGCGCTCTGGGCACCTTTTTTACGCAC GCGGCCCTGCAGAGCCTCCGCCTGTACCCCTTCACCGACGGCTGGCACCCCTTCGTGGTAGCGGCAGAGCTCATCTACTTCCTCTTCCTCCTCTACTACA TGGTGGTGCAGGGCAAGCGCATGAGTAAAGAGACGTGGGGCTATTTCTGCAGCAAGTGGAACCTTCTGGAGCTGGCCATCATCCTGGCCAGCTGGAGCGC CCTGGCGGTGTTTGTGAAGAGGGCTGTCCTGGCCGAAAGGGACCTCCAGCGCTGCCGGAACCACAGGGAGGAAGGCATCAGCTTCAGTGAGACAGCAGCA GCCGATGCCGCCCTTGGCTACATCATTGCCTTCCTGGTACTCCTGTCCACAGTGAAGCTTTGGCATCTGCTCAGGTTGAATCCCAAAATGAACATGATCA CGGCAGCCCTACGCCGTGCCTGGGGCGACATTTCAGGCTTTATGATTGTCATCCTTACCATGCTCCTGGCTTACTCCATCGCGTCAAACTTGATATTTGG TTGGAAACTCCGTTCCTACAAAACCCTCTTTGATGCGGCGGAGACGATGGTCAGCCTTCAGCTGGGAATCTTCAACTACGAGGAGGTCCTGGACTATAGC CCAGTGCTTGGCTCCTTCCTCATTGGATCCTGCATTGTTTTTATGACATTTGTGGTGCTGAACCTGTTTATCTCTGTCATCCTGGTGGCCTTCAGTGAGG AGCAAAAATACTATCAGCTGTCGGAGGAAGGGGAGATCGTAGATTTGCTGCTGATGAAAATACTCAGTTTCCTGGGCATTAAGTCTAAGAGAGAGGAGCC TGGAAGCAGCAGGGAGCAGCCTGGGTCTCTGTCCCAGACTCGCCACTCTCGACCAGCACAAGCTTTGCCCAAGGACTAAGCTGTTCGTCCACACGCCACC ATCTACCAGTGGGGACGCCCAGGGCCTCGGGCGTACGCTTACCAGCGACTCTATAGTCTCTCTAGGTCATAGCTTTCATGTCCATTGAAGAATTACCAAG CCCAGCAAGTAAAAAAAATTACAATAACAGAGATATATGTAAAATTGCCAATACTATGAGAGCTTCTTTGTTCAAATGTATTTCCTCTTATTATAAATAA AACAAATATTACATGGA

refseq_PKD1L2.F1 (forward primer)
refseq_PKD1L2.R1 (reverse primer)
Single exon skipping

Frame 0

MSAVGLVLLVLALRLRATTVKPEEGSFCSNSQV AFRDACYEFVPLGRTFRDAQSWCEGQGGHLVFIQ DEGTQWFLQKHISQDREWWIGLTWNLARNGTTE GPGTWLDTSNVTYSNWHGGQAAAAPDTCGHIGR GPSSEWVTSDCAQTFAFMCEFRVGQSLACEGLNA TVHCGLGQVIQVQDAVYGRQNPHFCTQDAGRPS DLEQGCSWANVKEEVAGQCQELQSCQVAADETY FGNLCPTQGSYLWVQYQCREALQLMVSSESFIFD NVTISLTWLLSPYIGNLSCIISTGDSHTFDPYN PPSVSSNVTHQFTSPGEFTVFAECTTSEWHVTA QRQVTVRDKMETLSVTACSGLSQSGAGPLCQAVF GDPLWIQVELDGGTGVTYTVLLGDITLAESTTQ KGSLPYNLILDRETQKLMGPGRHRLEIQATGNT TTSTISRNITVHLVELLSGLQASWASDHLELGQD LLITISLAQGTPEELTFEVAGLNATFSHEQVSF GEPFGICRLAVPVEGTFLVTMLVRNAFSNLSLE IGNITITAPSGLQEPSGMNAEGKSKDKGDMEVYI QPGPYVDPFTTVTLGWPDNDKELRFQWSCGSCW ALWSSCVERQLLRTDQRELVVPASCLPPPDSAV TLRLAVLRGQELENRAEQCLYVSAPWELRPRVSC ERNCRPVNASKDILLRVTMGEDSPVAMFSWYLD NTPTEQAEPLLDACRLRGFWPRSLTLLQSNTST LLLNSSFLQSRGEVIRIRATALTRHAYGEDTYVI STVPPREVPACTIAPEEGTVLTSFAIFCNASTA LGPLEFCFCLESGSCLHCGPEPALPSVYLPLGE ENNDFVLTVVISATNRAGDTQQTQAMAKVALGDT CVEDVAFQAAVSEKIPTALQGEGGPEQLLQLAK AVSSMLNQEHESQGSGQSLSIDVRQKVREHVLG SLSAVTTGLEDVQRVQELAEVLREVTCRSKELTP SAQWEASLALQHASEALLTVSAKARPEDQRRQA ATRDLFQAVGSVLEASLSNRPEEPAEASSSQIA TVLRLLRVMEHVQTTLLLGKLPGGLPAMLATPSI SVYTNRIQPWSWQGSSLRPDAADSATFMLPAAS SLSSLEGGQEPVDIKIMSFPKSPFPARSHFDVS GTVGGLRVTSPSGQLIPVKNLSENIEILLPRHSQ RHSQPTVLNLTSPEALWVNVTSGEATLGIQLHW RPDIALTLSLGYGYHPNKSSYDAQTHLVPMVAP DELPTWILSPQDLRFGEGVYYLTVVPESDLEPAP GRDLTVGITTFLSHCVFWDEVQETWDDSGCQVG PRTSPYQTHCLCNHLTFFGSTFLVMSNAINIHQ TAELFATFEDNPVVVTTVGCLCVVYVLVVIWARR KDAQDQAKVKVTVLEDNDPFAQYHYLVTVYTGH RRGAATSSKVTVTLYGLDGEREPHHLADPDTPV FERGAVDAFLLSTLFPLGELRSLRLWHDNSGDRP SWYVSRVLVYDLVMDRKWYFLCNSWLSINVGDC VLDKVFPVATEQDRKQFSHLFFMKTSAGFQDGH IWYSIFSRCARSSFTRVQRVSCCFSLLLCTMLTS IMFWGVPKDPAEQKMDLGKIEFTWQEVMIGLES SILMFPINLLIVQIFQNTRPRVAKEQNTGKWDR GSPNLTPSPQPMEDGLLTPEAVTKDVSRIVSSLF KALKVPSPALGWDSVNLMDINSLLALVEDVIYP QNTSGQVFWEEAKKREDPVTLTLGSSEMKEKSQ CPKPKAARSGPWKDSAYRQCLYLQLEHVEQELRL VGPRGFSQPHSHA*ALRQLQTLKGGLGVQPGTW APAHASALQVSKPPQGLPWWCILVGWLLVAATS GVAAFFTMLYGLHYGRASSLRWLISMAVSFVESM FVTQPLKVLGFAAFFALVLKRVDDEEDTVAPLP GHLLGPDPYALFRARRNSSRDVYQPPLTAAIEK MKTTHLKEQKAFALIREILAYLGFLWMLLLVAYG QRDPSAYHLNRHLQHSFTRGFSGVLGFREFFKW ANTTLVSNLYGHPPGFITDGNSKLVGSAQIRQV RVQESSCPLAQQPQAYLNGCRAPYSLDAEDMADY GEGWNATTLSNGSTRARTNVKGIPSGANSLCTG EEATWSPWGLIAKARQEFSAISLTTPGWTP*PE LCLWSPLSTTPTSTCSALSR*R*RPALWAPFLRT RPCRASACTPSPTAGTPSW*RQSSSTSSSSSTT WWCRASA*VKRRGAISAASGTFWSWPSSWPAGA PWRCL*RGLSWPKGTSSAAGTTGRKASASVRQQQ PMPPLATSLPSWYSCPQ*SFGICSG*IPK*T*S RQPYAVPGATFQAL*LSSLPCSWLTPSRQT*YL VGNSVPTKPSLMRRRRWSAFSWESSTTRRSWTIA QCLAPSSLDPALFL*HLWC*TCLSLSSWWPSVR SKNTISCRRKGRS*ICC**KYSVSWALSLRERS LEAAGSSLGLCPRLATLDQHKLCPRTKLFVHTPP STSGDAQGLGRTLTSDSIVSLGHSFHVH*RITK PSK*KKLQ*QRYM*NCQYYESFFVQMYFLLL*I KQILHG

Frame 1

*VQWAWYSWCLL*GLGPPLLSQRKAAFALTARW PSEMLAMNLCHSDAPSVMPRAGARGKEAIWSSF RTKAPSGFCRSTSPRTGNGGLDSRGTWHGMEPRR GRGLGWTPPM*PTATGMEGRPPLPLTPAATSGE ALPLSG*PRTAPRPSPSCASSGLARAWPARDSM PPCTVAWGRSSRSRMPSTGARIPISAPRMPGVLQ IWSRDAAGPTSRRRWQASARSYSHARWQQMRPT LETCVRLRAVTCGCSTSAGKPCS*WCPVRVSSL TMSPSP*RGSSHPT*ETCPV*LVQETATLLIPTT RRVCPAM*PTSSHLLGNSPCLLNAQPVSGM*QL RGR*PCETRWRRSV*LHAPACPSQEPALSARLS LGILCGFRWSLMEEQE*LTLCFWVT*PWPSPPPK RARYRTI*SWTEKPRN*WALGGTAWRSKPPATP PPLQSPETLQSTWWSCCQGCRPPGLLTIWSLDR TY*SPSHWLRAPRKS*PLRWLDSMQPSPTSK*AL ESHLGFAAWLFRLKAPFWSPCW*GMPSPT*VWK SGTSLSQPLPVSKNHLG*MLKERVKIKAIWRCT SNLVHMWILSRQ*PWAGQTMTRSYASNGHVGLAG LCGAAVLRGSCFAQTRGSWWFQHPACRRLTLLS PCAWLF*EAKSWRTGQSSASTCLRPGNSGLESA VRGTAGQLMPAKTFCSGSPWGRTLQWLCSAGIWT TPQQSRLSPSWMPADSEDFGQGP*PSSRATPPR CC*TARFCSPGERSSESEPQH*PGMPMGRTPM* SALCLPVRCLPALLPQRRAPF*RALPSSATPPQP WDPWSSASVWNQVPAYTVALNLPSHQCICHLER RTMTLC*Q*LFLPPIVQGTRSRPRPWLRWHSET HVLRM*HSRLPCQRKSPQLCKARVAPSSSSSWPR LCPPC*TKSMKARAQDSH*A*TSDRRSESMCWD HCLQSPPAWRTCRGCRSWPRC*ER*PAGVRNSH PRPSGRPAWLYSMPVRPC*Q*VPRPALRTRGARQ PPGTCFRLWAVCWKLP*ATDQKSLRRPAAARLP QCCGCFESWSMCRPPSCWENCQGAFQPCWPPPP SLCTQTEYNPGVGKAPPCALMPQTLQPSCCPLPP PSALWRAARSPWI*RS*VSQRAPFQPEATLMSA GLSVASV*PALVVNSYL*RICRRISRSCCPGIH KDTASRPC*T*PVLKLCG*T*LQGRQPWGSSCTG DQTLHSRLAWAMATTPTRAATMPKLTSYQWWLQ MSCPRGS*AHRTCVLEKGSTI*LWSLSLTWSQP PAGTSRLASPPSCLTVCSGMRSRRLGTTQDARWG LGPAPTRHTASATTSLSSEARSW*CPMPSTSTR LLSSLPPLRTTLWS*PPWAACVWSTCWW*SGRG GRTLRIRPR*RSQCWKTMIPLLSTTTW*QSTQDT DEGQPRPQR*LSPCMAWMERESPTTWLIPTLRF LSEEQWMPSSSPPCSPWENCGASGCGMTTQGTG HRGM*AGCWSMTW*WTGSGISCATPGYPSMLEIA SSIRCFLWPRSRTENNSATCFS*RLPRASRMDT SGIRSSAAALAAASPASRGCPAASPCCCAPC*P ASCSGGSPRTQLSKRWTWVKLNSPGRR**LAWRA PSSCSPSTS*LFRSFRTPVPGSRRSRTLENGTG GPPT*LPPHSPWRTAF*HLRQ*PRMCQESSAPS SKLSRCHPPPWAGTQ*T*WTSTVSSPWWKMSFIH RTHQGRCSGRKPKRERTL*HSLWGHQK*KRNHS VPSPRRHGVAPGRTAPTGSVCTFSWNTWSKSCG WWGPEASPSPTAMPRPSGSCRP*RAAWGYSRAPG PLHMPALFR*ANPLKACPGGASWWAGSW*RPPV AWRPSSPCSTACTTGGPAPSGGSSPWLSPSWRA CSSPSP*RCWDSLLSLHWS*REWTMRRILWPRCQ DICWAQTPMPCSEHEETAAGMSTSHLSPLPLRR *KPPTSRNRKHLPSSEKSWHTWASCGCYCSWPT GRGTPAPTTSTDTSSTASPGAFQVCSASESSSSG PTPPS*VTCMVTPQALSLMGTPSWLAVPRFVK* GSRKALALLPSSRRHISTDAVHHIPWMLKTWQT MGKAGMPPPSVMAVPEPGPTSRVSHLGQTHCVPG RRLRGPLGD*SPKHVKNSPLSL*QHLAGRPDQS CVCGVHCLQRQRQPVLHCHADARDQRSGHLFYA RGPAEPPPVPLHRRLAPLRGSGRAHLLPLPPLLH GGAGQAHE*RDVGLFLQQVEPSGAGHHPGQLER PGGVCEEGCPGRKGPPALPEPQGGRHQLQ*DSS SRCRPWLHHCLPGTPVHSEALASAQVESQNEHDH GSPTPCLGRHFRLYDCHPYHAPGLLHRVKLDIW LETPFLQNPL*CGGDDGQPSAGNLQLRGGPGL* PSAWLLPHWILHCFYDICGAEPVYLCHPGGLQ*G AKILSAVGGRGDRRFAADENTQFPGH*V*ERGA WKQQGAAWVSVPDSPLSTSTSFAQGLSCSSTRH HLPVGTPRASGVRLPATL*SL*VIAFMSIEELPS PASKKNYNNRDICKIANTMRASLFKCISSYYK* NKYYM

Frame 2

ECSGLGTPGACSEA*GHHC*ARGRQLLL*QPGG LQRCLL*ICATRTHLP*CPELVRGARRPFGLHS GRRHPVVSAEAHLPGQGMVDWTHVELGTEWNHG GAGDLVGHLQCDLQQLAWRAGRRCP*HLRPHRER PFL*VGDLGLRPDLRLHVRVPGWPEPGLRGTQC HRALWLGAGHPGPGCRLRAPESPFLHPGCRASF RSGAGMQLGQRQGGGGRPVPGATVMPGGSR*DLL WKPVSDSGQLPVGAVPVPGSPAADGVQ*EFHL* QCHHLPDVAPLTLHRKPVLYN*YRRQPHF*SLQ PAECVQQCDPPVHISWGIHRVC*MHNQ*VACDSS EAGDRARQDGDAQCDCMLRPVPVRSRPSLPGCL WGSSVDSGGA*WRNRSDLHCAFG*HNPGRVHHP KGLATVQSDPGQRNPETDGPWEAPPGDPSHRQHH HLYNLQKHYSPLGGAAVRAAGLLGF*PFGAWTG PIDHHLIGSGHPGRADL*GGWTQCNLLPRASEL WRAIWDLPPGCSG*RHLSGHHAGEECLLQPEFGN REHHYHSPFRSPRTIWDEC*RKE*R*RRYGGVH PTWSICGSFHDSDPGLARQ*QGVTLPMVMWVLL GSVEQLC*EAAASHRPEGAGGSSILPAAA*LCCH PAPGCSERPRAGEQGRAVPLRVCALGTQASSQL *EELQAS*CQQRHSAQGHHGGGLSSGYVQLVFG QHPNRAG*APPGCLQTQRILAKVLNPPPEQHLHV AVEQLVSAVPGRGHPNQSHSTDQACLWGGHLCD QHCASP*GACLHYCPRGGHRSDELCHLLQRLHS PGTPGVLLLSGIRFLPTLWP*TCPPISVSATWRG EQ*LCADSSYFCHQSCRGHAADPGHG*GGTRRH MC*GCSIPGCRVRENPHSSARRGWPRAAPPAGQ GCVLHAEPRA*KPGLRTVTEHRRQTEGQRACAGI TVCSHHRLGGRAEGAGAGRGAERGDLPE*GTHT LGPVGGQLGSTACQ*GPVDSECQGPP*GPEAPG SHQGPVSGCGQCAGSFPEQQTRRACGGQQQPDCH SAAAASSHGACADHPPAGKTARGPSSHAGHPLH LCVHKQNTTLELARLLPAP*CRRLCNLHAARCL LPQLSGGRPGARGYKDHEFPKEPLSSPKPL*CQR DCRWPPCDQP*WSTHTCEESVGEYRDPAAPAFT KTQPADRVEPDQS*SFVGERDFRGGNLGDPAAL ETRHCTHA*PGLWLPPQQEQLRCPNSPRTNGGSR *AAHVDPEPTGPAFWRRGLLFDCGP*V*PGASP RQGPHGWHHHLPVSLCVLG*GPGDLGRLRMPGG ASDQPLPDTLPLQPPHFLRKHVPGDVQCHQHPPD C*ALCHL*GQPCGRDHRGLPVCGLRAGGDLGEE EGRSGSGQGEGHSAGRQ*SLCSVPLPGDSLHRT PTRGSHVLKGDCHPVWPGWRERAPPPG*SRHSGF *ARSSGCLPPLHPVPPGRTAEPPAVA*QLRGPA IVVCEPGAGL*PGDGPEVVFPVQLLAIHQCWRL RPR*GVSCGHGAGQKTIQPPVFHEDFRGLPGWTH LVFDLQPLRSQQLHPRPEGVLLLLPAAVHHADQ HHVLGGPQGPS*AKDGLG*N*IHLAGGDDWPGE LHPHVPHQPPDCSDLSEHPSPGREGAEHWKMGPG VPQPDSLPTAHGGRPSDT*GSDQGCVKNRQLPL QSSQGAIPRLGLGLSELDGHQQSPRLGGRCHLS TEHIRAGVLGGSQKERGPCNTHFGVIRNEREITV SQAQGGTEWPLEGQRLQAVSVPSAGTRGARAAA GGAPRLLPAPQPCLGPQAAADPEGRPGGTAGHL GPCTCQRSSGEQTPSRPALVVHPGGLAPGSGHQW RGGLLHHALRPALREGQLPQVAHLHGCLLRGEH VRHPAPEGAGIRCFLCTGLEESGR*GGYCGPAA RTSVGPRPLCLVPSTKKQQQGCLPATSHRCH*ED ENHPPQGTESICPHQRNPGILGLPVDATARGLR AEGPQRLPPQQTPPAQLHQGLFRCARLPRVLQV GQHHPRE*PVWSPPRLYH*WELQAGWQCPDSSSE GPGKLLPSCPAAAGISQRMPCTIFPGC*RHGRL WGRLECHHPQ*WQYQSQDQRQGYPIWGKLTVYR GGGYVVPLGTDRQSTSRILRYLFDNTWLDALTRA VFVESTVYNANVNLFCIVTLTLETSALGTFFTH AALQSLRLYPFTDGWHPFVVAAELIYFLFLLYY MVVQGKRMSKETWGYFCSKWNLLELAIILASWSA LAVFVKRAVLAERDLQRCRNHREEGISFSETAA ADAALGYIIAFLVLLSTVKLWHLLRLNPKMNMI TAALRRAWGDISGFMIVILTMLLAYSIASNLIFG WKLRSYKTLFDAAETMVSLQLGIFNYEEVLDYS PVLGSFLIGSCIVFMTFVVLNLFISVILVAFSE EQKYYQLSEEGEIVDLLLMKILSFLGIKSKREEP GSSREQPGSLSQTRHSRPAQALPKD*AVRPHAT IYQWGRPGPRAYAYQRLYSLSRS*LSCPLKNYQ AQQVKKITITEIYVKLPIL*ELLCSNVFPLIINK TNITW