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Sequences

Sequence NM_000935

ACACCGCCCTCCCGCCAGACTCCCGGCGGCTCCTCCTCCCTCTCCCAAACCCACTCCCAAAGCTAAGTGCAGGCTTCCCCGTTCCAGCCAGAAGCGCTGC GTGAGCCTCCACACGTAGCCGCAGGCAGCTCCTTAAATAGCGTCCGCGCTGAGCAAACAGTCCAGACGTGGGGCCCAGGAGGGCGAGCTGAGGCGACCGC ACCGGGCGCGCAGCGGCGGCGGGTCAGCCGGCGGCCAATAGCCAGGGCGCGGCCCGCCCCGTCGCCTCCCCTCGGGGAGCCTATAAGGCCTCCGCAGCGC CCCGGGCGCCTGCTGCTCCGTGCCTCCACCGACGACCTCACTCAGCTGCGTTACGCGCCGCTCCGGCTGCCGGCCGCGCGCCTTGCCCGCCGGCTCCCGC CCGCAATCGGCGGCTCAGGGCGGACCCGGGTCTCTGCGTTCTCGCGAGAAGCGCGGCGCTGCGGGGCCGTGGGCGCCTGAGCCCGCGCGGCCCTCGAGGG CCGAATATGGGGGGATGCACGGTGAAGCCTCAGCTGCTGCTCCTGGCGCTCGTCCTCCACCCCTGGAATCCCTGTCTGGGTGCGGACTCGGAGAAGCCCT CGAGCATCCCCACAGATAAATTATTAGTCATAACTGTAGCAACAAAAGAAAGTGATGGATTCCATCGATTTATGCAGTCAGCCAAATATTTCAATTATAC TGTGAAGGTCCTTGGTCAAGGAGAAGAATGGAGAGGTGGTGATGGAATTAATAGTATTGGAGGGGGCCAGAAAGTGAGATTAATGAAAGAAGTCATGGAA CACTATGCTGATCAAGATGATCTGGTTGTCATGTTTACTGAATGCTTTGATGTCATATTTGCTGGTGGTCCAGAAGAAGTTCTAAAAAAATTCCAAAAGG CAAACCACAAAGTGGTCTTTGCAGCAGATGGAATTTTGTGGCCAGATAAAAGACTAGCAGACAAGTATCCTGTTGTGCACATTGGGAAACGCTATCTGAA TTCAGGAGGATTTATTGGCTATGCTCCATATGTCAACCGTATAGTTCAACAATGGAATCTCCAGGATAATGATGATGATCAGCTCTTTTACACTAAAGTT TACATTGATCCACTGAAAAGGGAAGCTATTAACATCACATTGGATCACAAATGCAAAATTTTCCAGACCTTAAATGGAGCTGTAGATGAAGTTGTTTTAA AATTTGAAAATGGCAAAGCCAGAGCTAAGAATACATTTTATGAAACATTACCAGTGGCAATTAATGGAAATGGACCCACCAAGATTCTCCTGAATTATTT TGGAAACTATGTACCCAATTCATGGACACAGGATAATGGCTGCACTCTTTGTGAATTCGATACAGTCGACTTGTCTGCAGTAGATGTCCATCCAAACGTA TCAATAGGTGTTTTTATTGAGCAACCAACCCCTTTTCTACCTCGGTTTCTGGACATATTGTTGACACTGGATTACCCAAAAGAAGCACTTAAACTTTTTA TTCATAACAAAGAAGTTTATCATGAAAAGGACATCAAGGTATTTTTTGATAAAGCTAAGCATGAAATCAAAACTATAAAAATAGTAGGACCAGAAGAAAA TCTAAGTCAAGCGGAAGCCAGAAACATGGGAATGGACTTTTGCCGTCAGGATGAAAAGTGTGATTATTACTTTAGTGTGGATGCAGATGTTGTTTTGACA AATCCAAGGACTTTAAAAATTTTGATTGAACAAAACAGAAAGATCATTGCTCCTCTTGTAACTCGTCATGGAAAGCTGTGGTCCAATTTCTGGGGAGCAT TGAGTCCTGATGGATACTATGCACGATCTGAAGATTATGTGGATATTGTTCAAGGGAATAGAGTAGGAGTATGGAATGTCCCATATATGGCTAATGTGTA CTTAATTAAAGGAAAGACACTCCGATCAGAGATGAATGAAAGGAACTATTTTGTTCGTGATAAACTGGATCCTGATATGGCTCTTTGCCGAAATGCTAGA GAAATGGGTGTATTTATGTACATTTCTAATAGACATGAATTTGGAAGGCTATTATCCACTGCTAATTACAATACTTCCCATTATAACAATGACCTCTGGC AGATTTTTGAAAATCCTGTGGACTGGAAGGAAAAGTATATAAACCGTGATTATTCAAAGATTTTCACTGAAAATATAGTTGAACAGCCCTGTCCAGATGT CTTTTGGTTCCCCATATTTTCTGAAAAAGCCTGTGATGAATTGGTAGAAGAAATGGAACATTACGGCAAATGGTCTGGGGGAAAACATCATGATAGCCGT ATATCTGGTGGTTATGAAAATGTCCCAACTGATGATATCCACATGAAGCAAGTTGATCTGGAGAATGTATGGCTTCATTTTATCCGGGAGTTCATTGCAC CAGTTACACTGAAGGTCTTTGCAGGCTATTATACGAAGGGATTTGCACTACTGAATTTTGTAGTAAAATACTCCCCTGAACGACAGCGTTCTCTTCGTCC TCATCATGATGCTTCTACATTTACCATAAACATTGCACTTAATAACGTGGGAGAAGACTTTCAGGGAGGTGGTTGCAAATTTCTAAGGTACAATTGCTCT ATTGAGTCACCACGAAAAGGCTGGAGCTTCATGCATCCTGGGAGACTCACACATTTGCATGAAGGACTTCCTGTTAAAAATGGAACAAGATACATTGCAG TGTCATTTATAGATCCCTAAGTTATTTACTTTTCATTGAATTGAAATTTATTTTGGATGAATGACTGGCATGAACACGTCTTTGAAGTTGTGGCTGAGAA GATGAGAGGAATATTTAAATAACATCAACAGAACAACTTCACTTTGGGCCAAACATTTGAAAAACTTTTTATAAAAAATTGTTTGATATTTCTTAATGTC TGCTCTGAGCCTTAAAACACAGATTGAAGAAGAAAAGAAAGAAAAAACTTAAATATTTATTTCTATGCTTTGTTGCCTCTGAGAATAATGACAATTTATG AATTTGTGTTTCAAATTGATAAAATATTTAGGTACAAATAACAAGACTAATAATATTTTCTTATTTAAAAAAAGCATGGGAAGATTTTTATTTATCAAAA TATAGAGGAAATGTAGACAAAATGGATATAAATGAAAATTACCATGTTGTAAAACCTTGAAAATCAGATTCTAACTGGATTTGTATGCAACTAAGTATTT TTCTGAACACCTATGCAGGTCTTATTTACAGTAGTTACTAAGGGAACACACAAAGAATTACACAACGTTTTCCTCAAGAAAATGGTACAAAACACAACCG AGGAGCGTATACAGTTGAAAACATTTTTGTTTTGATTGGAAGGCAGATTATTTTATATTAGTATTAAAAATCAAACCCTATGTTTCTTTCAGATGAATCT TCCAAAGTGGATTATATTAAGCAGGTATTAGATTTAGGAAAACCTTTCCATTTCTTAAAGTATTATCAAGTGTCAAGATCAGCAAGTGTCCTTAAGTCAA ACAGGTTTTTTTTGTTGTTGTTTTTGCTTTGTTTCCTTTTTTAGAAAGTTCTAGAAAATAGGAAAACGAAAAATTTCATTGAGATGAGTAGTGCATTTAA TTATTTTTTAAAAAACTTTTTAAGTACTTGAATTTTATATCAGGAAAACAAAGTTGTTGAGCCTTGCTTCTTCCGTTTTGCCCTTTGTCTCGCTCCTTAT TCTTTTTTTGGGGGGAGGGTTATTTGCTTTTTTATCTTCCTGGCATAATTTCCATTTTATTCTTCTGAGTGTCTATGTTAACTTCCCTCTATCCCGCTTA TAAAAAAATTCTCCAACAAAAATACTTGTTGACTTGATGTTTTATCACTTCTCTAAGTAAGGTTGAAATATCCTTATTGTAGCTACTGTTTTTAATGTAA AGGTTAAACTTGAAAAGAAATTCTTAATCACGGTGCCAAAATTCATTTTCTAACACCATGTGTTAGAAAATTATAAAAAATAAAATAATTTTAGAAA

refseq_PLOD2.F1 (forward primer)
refseq_PLOD2.R1 (reverse primer)
Single exon skipping

Frame 0

TPPSRQTPGGSSSLSQTHSQS*VQASPFQPEAL REPPHVAAGSSLNSVRAEQTVQTWGPGGRAEATA PGAQRRRVSRRPIARARPAPSPPLGEPIRPPQR PGRLLLRASTDDLTQLRYAPLRLPAARLARRLP PAIGGSGRTRVSAFSREARRCGAVGA*ARAALEG RIWGDAR*SLSCCSWRSSSTPGIPVWVRTRRSP RASPQINY*S*L*QQKKVMDSIDLCSQPNISII L*RSLVKEKNGEVVMELIVLEGARK*D**KKSWN TMLIKMIWLSCLLNALMSYLLVVQKKF*KNSKR QTTKWSLQQMEFCGQIKD*QTSILLCTLGNAI* IQEDLLAMLHMSTV*FNNGISRIMMMISSFTLKF TLIH*KGKLLTSHWITNAKFSRP*MEL*MKLF* NLKMAKPELRIHFMKHYQWQLMEMDPPRFS*II LETMYPIHGHRIMAALFVNSIQSTCLQ*MSIQTY Q*VFLLSNQPLFYLGFWTYC*HWITQKKHLNFL FITKKFIMKRTSRYFLIKLSMKSKL*K**DQKK I*VKRKPETWEWTFAVRMKSVIITLVWMQMLF*Q IQGL*KF*LNKTERSLLLL*LVMESCGPISGEH *VLMDTMHDLKIMWILFKGIE*EYGMSHIWLMC T*LKERHSDQR*MKGTILFVINWILIWLFAEMLE KWVYLCTFLIDMNLEGYYPLLITILPIITMTSG RFLKILWTGRKSI*TVIIQRFSLKI*LNSPVQM SFGSPYFLKKPVMNW*KKWNITANGLGENIMIAV YLVVMKMSQLMIST*SKLIWRMYGFILSGSSLH QLH*RSLQAIIRRDLHY*IL**NTPLNDSVLFV LIMMLLHLP*TLHLITWEKTFREVVANF*GTIAL LSHHEKAGASCILGDSHICMKDFLLKMEQDTLQ CHL*IPKLFTFH*IEIYFG*MTGMNTSLKLWLR R*EEYLNNINRTTSLWAKHLKNFL*KIV*YFLMS ALSLKTQIEEEKKEKT*IFISMLCCL*E**QFM NLCFKLIKYLGTNNKTNNIFLFKKSMGRFLFIK I*RKCRQNGYK*KLPCCKTLKIRF*LDLYATKYF SEHLCRSYLQ*LLREHTKNYTTFSSRKWYKTQP RSVYS*KHFCFDWKADYFILVLKIKPYVSFR*I FQSGLY*AGIRFRKTFPFLKVLSSVKISKCP*VK QVFFVVVFALFPFLESSRK*ENEKFH*DE*CI* LFFKKLFKYLNFISGKQSC*ALLLPFCPLSRSL FFFWGEGYLLFYLPGIISILFF*VSMLTSLYPAY KKILQQKYLLT*CFITSLSKVEISLL*LLFLM* RLNLKRNS*SRCQNSFSNTMC*KIIKNKIILE

Frame 1

HRPPARLPAAPPPSPKPTPKAKCRLPRSSQKRC VSLHT*PQAAP*IASALSKQSRRGAQEGELRRP HRARSGGGSAGGQ*PGRGPPRRLPSGSL*GLRSA PGACCSVPPPTTSLSCVTRRSGCRPRALPAGSR PQSAAQGGPGSLRSREKRGAAGPWAPEPARPSR AEYGGMHGEASAAAPGARPPPLESLSGCGLGEAL EHPHR*IISHNCSNKRK*WIPSIYAVSQIFQLY CEGPWSRRRMERW*WN**YWRGPESEINERSHG TLC*SR*SGCHVY*ML*CHICWWSRRSSKKIPKG KPQSGLCSRWNFVAR*KTSRQVSCCAHWETLSE FRRIYWLCSICQPYSSTMESPG****SALLH*S LH*STEKGSY*HHIGSQMQNFPDLKWSCR*SCFK I*KWQSQS*EYIL*NITSGN*WKWTHQDSPELF WKLCTQFMDTG*WLHSL*IRYSRLVCSRCPSKR INRCFY*ATNPFSTSVSGHIVDTGLPKRST*TFY S*QRSLS*KGHQGIF**S*A*NQNYKNSRTRRK SKSSGSQKHGNGLLPSG*KV*LLL*CGCRCCFD KSKDFKNFD*TKQKDHCSSCNSSWKAVVQFLGSI ES*WILCTI*RLCGYCSRE*SRSMECPIYG*CV LN*RKDTPIRDE*KELFCS**TGS*YGSLPKC* RNGCIYVHF**T*IWKAIIHC*LQYFPL*Q*PLA DF*KSCGLEGKVYKP*LFKDFH*KYS*TALSRC LLVPHIF*KSL**IGRRNGTLRQMVWGKTS**P YIWWL*KCPN**YPHEAS*SGECMASFYPGVHCT SYTEGLCRLLYEGICTTEFCSKILP*TTAFSSS SS*CFYIYHKHCT**RGRRLSGRWLQISKVQLL Y*VTTKRLELHASWETHTFA*RTSC*KWNKIHCS VIYRSLSYLLFIELKFILDE*LA*TRL*SCG*E DERNI*ITSTEQLHFGPNI*KTFYKKLFDIS*C LL*ALKHRLKKKRKKKLKYLFLCFVASENNDNL* ICVSN**NI*VQITRLIIFSYLKKAWEDFYLSK YRGNVDKMDINENYHVVKP*KSDSNWICMQLSI FLNTYAGLIYSSY*GNTQRITQRFPQENGTKHNR GAYTVENIFVLIGRQIILY*Y*KSNPMFLSDES SKVDYIKQVLDLGKPFHFLKYYQVSRSASVLKS NRFFLLLFLLCFLF*KVLENRKTKNFIEMSSAFN YFLKNFLST*ILYQENKVVEPCFFRFALCLAPY SFFGGRVICFFIFLA*FPFYSSECLC*LPSIPL IKKFSNKNTC*LDVLSLL*VRLKYPYCSYCF*CK G*T*KEILNHGAKIHFLTPCVRKL*KIK*F*K

Frame 2

TALPPDSRRLLLPLPNPLPKLSAGFPVPARSAA *ASTRSRRQLLK*RPR*ANSPDVGPRRAS*GDR TGRAAAAGQPAANSQGAARPVASPRGAYKASAA PRAPAAPCLHRRPHSAALRAAPAAGRAPCPPAPA RNRRLRADPGLCVLARSAALRGRGRLSPRGPRG PNMGGCTVKPQLLLLALVLHPWNPCLGADSEKP SSIPTDKLLVITVATKESDGFHRFMQSAKYFNYT VKVLGQGEEWRGGDGINSIGGGQKVRLMKEVME HYADQDDLVVMFTECFDVIFAGGPEEVLKKFQK ANHKVVFAADGILWPDKRLADKYPVVHIGKRYLN SGGFIGYAPYVNRIVQQWNLQDNDDDQLFYTKV YIDPLKREAINITLDHKCKIFQTLNGAVDEVVL KFENGKARAKNTFYETLPVAINGNGPTKILLNYF GNYVPNSWTQDNGCTLCEFDTVDLSAVDVHPNV SIGVFIEQPTPFLPRFLDILLTLDYPKEALKLF IHNKEVYHEKDIKVFFDKAKHEIKTIKIVGPEEN LSQAEARNMGMDFCRQDEKCDYYFSVDADVVLT NPRTLKILIEQNRKIIAPLVTRHGKLWSNFWGA LSPDGYYARSEDYVDIVQGNRVGVWNVPYMANVY LIKGKTLRSEMNERNYFVRDKLDPDMALCRNAR EMGVFMYISNRHEFGRLLSTANYNTSHYNNDLW QIFENPVDWKEKYINRDYSKIFTENIVEQPCPDV FWFPIFSEKACDELVEEMEHYGKWSGGKHHDSR ISGGYENVPTDDIHMKQVDLENVWLHFIREFIA PVTLKVFAGYYTKGFALLNFVVKYSPERQRSLRP HHDASTFTINIALNNVGEDFQGGGCKFLRYNCS IESPRKGWSFMHPGRLTHLHEGLPVKNGTRYIA VSFIDP*VIYFSLN*NLFWMNDWHEHVFEVVAEK MRGIFK*HQQNNFTLGQTFEKLFIKNCLIFLNV CSEP*NTD*RRKERKNLNIYFYALLPLRIMTIY EFVFQIDKIFRYK*QD**YFLI*KKHGKIFIYQN IEEM*TKWI*MKITML*NLENQILTGFVCN*VF F*TPMQVLFTVVTKGTHKELHNVFLKKMVQNTT EERIQLKTFLF*LEGRLFYISIKNQTLCFFQMNL PKWIILSRY*I*ENLSIS*SIIKCQDQQVSLSQ TGFFCCCFCFVSFFRKF*KIGKRKISLR*VVHL IIF*KTF*VLEFYIRKTKLLSLASSVLPFVSLLI LFLGGGLFAFLSSWHNFHFILLSVYVNFPLSRL *KNSPTKILVDLMFYHFSK*G*NILIVATVFNV KVKLEKKFLITVPKFIF*HHVLENYKK*NNFR

Sequence NM_182943

ACACCGCCCTCCCGCCAGACTCCCGGCGGCTCCTCCTCCCTCTCCCAAACCCACTCCCAAAGCTAAGTGCAGGCTTCCCCGTTCCAGCCAGAAGCGCTGC GTGAGCCTCCACACGTAGCCGCAGGCAGCTCCTTAAATAGCGTCCGCGCTGAGCAAACAGTCCAGACGTGGGGCCCAGGAGGGCGAGCTGAGGCGACCGC ACCGGGCGCGCAGCGGCGGCGGGTCAGCCGGCGGCCAATAGCCAGGGCGCGGCCCGCCCCGTCGCCTCCCCTCGGGGAGCCTATAAGGCCTCCGCAGCGC CCCGGGCGCCTGCTGCTCCGTGCCTCCACCGACGACCTCACTCAGCTGCGTTACGCGCCGCTCCGGCTGCCGGCCGCGCGCCTTGCCCGCCGGCTCCCGC CCGCAATCGGCGGCTCAGGGCGGACCCGGGTCTCTGCGTTCTCGCGAGAAGCGCGGCGCTGCGGGGCCGTGGGCGCCTGAGCCCGCGCGGCCCTCGAGGG CCGAATATGGGGGGATGCACGGTGAAGCCTCAGCTGCTGCTCCTGGCGCTCGTCCTCCACCCCTGGAATCCCTGTCTGGGTGCGGACTCGGAGAAGCCCT CGAGCATCCCCACAGATAAATTATTAGTCATAACTGTAGCAACAAAAGAAAGTGATGGATTCCATCGATTTATGCAGTCAGCCAAATATTTCAATTATAC TGTGAAGGTCCTTGGTCAAGGAGAAGAATGGAGAGGTGGTGATGGAATTAATAGTATTGGAGGGGGCCAGAAAGTGAGATTAATGAAAGAAGTCATGGAA CACTATGCTGATCAAGATGATCTGGTTGTCATGTTTACTGAATGCTTTGATGTCATATTTGCTGGTGGTCCAGAAGAAGTTCTAAAAAAATTCCAAAAGG CAAACCACAAAGTGGTCTTTGCAGCAGATGGAATTTTGTGGCCAGATAAAAGACTAGCAGACAAGTATCCTGTTGTGCACATTGGGAAACGCTATCTGAA TTCAGGAGGATTTATTGGCTATGCTCCATATGTCAACCGTATAGTTCAACAATGGAATCTCCAGGATAATGATGATGATCAGCTCTTTTACACTAAAGTT TACATTGATCCACTGAAAAGGGAAGCTATTAACATCACATTGGATCACAAATGCAAAATTTTCCAGACCTTAAATGGAGCTGTAGATGAAGTTGTTTTAA AATTTGAAAATGGCAAAGCCAGAGCTAAGAATACATTTTATGAAACATTACCAGTGGCAATTAATGGAAATGGACCCACCAAGATTCTCCTGAATTATTT TGGAAACTATGTACCCAATTCATGGACACAGGATAATGGCTGCACTCTTTGTGAATTCGATACAGTCGACTTGTCTGCAGTAGATGTCCATCCAAACGTA TCAATAGGTGTTTTTATTGAGCAACCAACCCCTTTTCTACCTCGGTTTCTGGACATATTGTTGACACTGGATTACCCAAAAGAAGCACTTAAACTTTTTA TTCATAACAAAGAAGTTTATCATGAAAAGGACATCAAGGTATTTTTTGATAAAGCTAAGCATGAAATCAAAACTATAAAAATAGTAGGACCAGAAGAAAA TCTAAGTCAAGCGGAAGCCAGAAACATGGGAATGGACTTTTGCCGTCAGGATGAAAAGTGTGATTATTACTTTAGTGTGGATGCAGATGTTGTTTTGACA AATCCAAGGACTTTAAAAATTTTGATTGAACAAAACAGAAAGATCATTGCTCCTCTTGTAACTCGTCATGGAAAGCTGTGGTCCAATTTCTGGGGAGCAT TGAGTCCTGATGGATACTATGCACGATCTGAAGATTATGTGGATATTGTTCAAGGGAATAGAGTAGGAGTATGGAATGTCCCATATATGGCTAATGTGTA CTTAATTAAAGGAAAGACACTCCGATCAGAGATGAATGAAAGGAACTATTTTGTTCGTGATAAACTGGATCCTGATATGGCTCTTTGCCGAAATGCTAGA GAAATGACTTTACAAAGGGAAAAAGACTCCCCTACTCCGGAAACATTCCAAATGCTCAGCCCCCCAAAGGGTGTATTTATGTACATTTCTAATAGACATG AATTTGGAAGGCTATTATCCACTGCTAATTACAATACTTCCCATTATAACAATGACCTCTGGCAGATTTTTGAAAATCCTGTGGACTGGAAGGAAAAGTA TATAAACCGTGATTATTCAAAGATTTTCACTGAAAATATAGTTGAACAGCCCTGTCCAGATGTCTTTTGGTTCCCCATATTTTCTGAAAAAGCCTGTGAT GAATTGGTAGAAGAAATGGAACATTACGGCAAATGGTCTGGGGGAAAACATCATGATAGCCGTATATCTGGTGGTTATGAAAATGTCCCAACTGATGATA TCCACATGAAGCAAGTTGATCTGGAGAATGTATGGCTTCATTTTATCCGGGAGTTCATTGCACCAGTTACACTGAAGGTCTTTGCAGGCTATTATACGAA GGGATTTGCACTACTGAATTTTGTAGTAAAATACTCCCCTGAACGACAGCGTTCTCTTCGTCCTCATCATGATGCTTCTACATTTACCATAAACATTGCA CTTAATAACGTGGGAGAAGACTTTCAGGGAGGTGGTTGCAAATTTCTAAGGTACAATTGCTCTATTGAGTCACCACGAAAAGGCTGGAGCTTCATGCATC CTGGGAGACTCACACATTTGCATGAAGGACTTCCTGTTAAAAATGGAACAAGATACATTGCAGTGTCATTTATAGATCCCTAAGTTATTTACTTTTCATT GAATTGAAATTTATTTTGGATGAATGACTGGCATGAACACGTCTTTGAAGTTGTGGCTGAGAAGATGAGAGGAATATTTAAATAACATCAACAGAACAAC TTCACTTTGGGCCAAACATTTGAAAAACTTTTTATAAAAAATTGTTTGATATTTCTTAATGTCTGCTCTGAGCCTTAAAACACAGATTGAAGAAGAAAAG AAAGAAAAAACTTAAATATTTATTTCTATGCTTTGTTGCCTCTGAGAATAATGACAATTTATGAATTTGTGTTTCAAATTGATAAAATATTTAGGTACAA ATAACAAGACTAATAATATTTTCTTATTTAAAAAAAGCATGGGAAGATTTTTATTTATCAAAATATAGAGGAAATGTAGACAAAATGGATATAAATGAAA ATTACCATGTTGTAAAACCTTGAAAATCAGATTCTAACTGGATTTGTATGCAACTAAGTATTTTTCTGAACACCTATGCAGGTCTTATTTACAGTAGTTA CTAAGGGAACACACAAAGAATTACACAACGTTTTCCTCAAGAAAATGGTACAAAACACAACCGAGGAGCGTATACAGTTGAAAACATTTTTGTTTTGATT GGAAGGCAGATTATTTTATATTAGTATTAAAAATCAAACCCTATGTTTCTTTCAGATGAATCTTCCAAAGTGGATTATATTAAGCAGGTATTAGATTTAG GAAAACCTTTCCATTTCTTAAAGTATTATCAAGTGTCAAGATCAGCAAGTGTCCTTAAGTCAAACAGGTTTTTTTTGTTGTTGTTTTTGCTTTGTTTCCT TTTTTAGAAAGTTCTAGAAAATAGGAAAACGAAAAATTTCATTGAGATGAGTAGTGCATTTAATTATTTTTTAAAAAACTTTTTAAGTACTTGAATTTTA TATCAGGAAAACAAAGTTGTTGAGCCTTGCTTCTTCCGTTTTGCCCTTTGTCTCGCTCCTTATTCTTTTTTTGGGGGGAGGGTTATTTGCTTTTTTATCT TCCTGGCATAATTTCCATTTTATTCTTCTGAGTGTCTATGTTAACTTCCCTCTATCCCGCTTATAAAAAAATTCTCCAACAAAAATACTTGTTGACTTGA TGTTTTATCACTTCTCTAAGTAAGGTTGAAATATCCTTATTGTAGCTACTGTTTTTAATGTAAAGGTTAAACTTGAAAAGAAATTCTTAATCACGGTGCC AAAATTCATTTTCTAACACCATGTGTTAGAAAATTATAAAAAATAAAATAATTTTAGAAA

refseq_PLOD2.F1 (forward primer)
refseq_PLOD2.R1 (reverse primer)
Single exon skipping

Frame 0

TPPSRQTPGGSSSLSQTHSQS*VQASPFQPEAL REPPHVAAGSSLNSVRAEQTVQTWGPGGRAEATA PGAQRRRVSRRPIARARPAPSPPLGEPIRPPQR PGRLLLRASTDDLTQLRYAPLRLPAARLARRLP PAIGGSGRTRVSAFSREARRCGAVGA*ARAALEG RIWGDAR*SLSCCSWRSSSTPGIPVWVRTRRSP RASPQINY*S*L*QQKKVMDSIDLCSQPNISII L*RSLVKEKNGEVVMELIVLEGARK*D**KKSWN TMLIKMIWLSCLLNALMSYLLVVQKKF*KNSKR QTTKWSLQQMEFCGQIKD*QTSILLCTLGNAI* IQEDLLAMLHMSTV*FNNGISRIMMMISSFTLKF TLIH*KGKLLTSHWITNAKFSRP*MEL*MKLF* NLKMAKPELRIHFMKHYQWQLMEMDPPRFS*II LETMYPIHGHRIMAALFVNSIQSTCLQ*MSIQTY Q*VFLLSNQPLFYLGFWTYC*HWITQKKHLNFL FITKKFIMKRTSRYFLIKLSMKSKL*K**DQKK I*VKRKPETWEWTFAVRMKSVIITLVWMQMLF*Q IQGL*KF*LNKTERSLLLL*LVMESCGPISGEH *VLMDTMHDLKIMWILFKGIE*EYGMSHIWLMC T*LKERHSDQR*MKGTILFVINWILIWLFAEMLE K*LYKGKKTPLLRKHSKCSAPQRVYLCTFLIDM NLEGYYPLLITILPIITMTSGRFLKILWTGRKS I*TVIIQRFSLKI*LNSPVQMSFGSPYFLKKPVM NW*KKWNITANGLGENIMIAVYLVVMKMSQLMI ST*SKLIWRMYGFILSGSSLHQLH*RSLQAIIR RDLHY*IL**NTPLNDSVLFVLIMMLLHLP*TLH LITWEKTFREVVANF*GTIALLSHHEKAGASCI LGDSHICMKDFLLKMEQDTLQCHL*IPKLFTFH *IEIYFG*MTGMNTSLKLWLRR*EEYLNNINRTT SLWAKHLKNFL*KIV*YFLMSALSLKTQIEEEK KEKT*IFISMLCCL*E**QFMNLCFKLIKYLGT NNKTNNIFLFKKSMGRFLFIKI*RKCRQNGYK*K LPCCKTLKIRF*LDLYATKYFSEHLCRSYLQ*L LREHTKNYTTFSSRKWYKTQPRSVYS*KHFCFD WKADYFILVLKIKPYVSFR*IFQSGLY*AGIRFR KTFPFLKVLSSVKISKCP*VKQVFFVVVFALFP FLESSRK*ENEKFH*DE*CI*LFFKKLFKYLNF ISGKQSC*ALLLPFCPLSRSLFFFWGEGYLLFYL PGIISILFF*VSMLTSLYPAYKKILQQKYLLT* CFITSLSKVEISLL*LLFLM*RLNLKRNS*SRC QNSFSNTMC*KIIKNKIILE

Frame 1

HRPPARLPAAPPPSPKPTPKAKCRLPRSSQKRC VSLHT*PQAAP*IASALSKQSRRGAQEGELRRP HRARSGGGSAGGQ*PGRGPPRRLPSGSL*GLRSA PGACCSVPPPTTSLSCVTRRSGCRPRALPAGSR PQSAAQGGPGSLRSREKRGAAGPWAPEPARPSR AEYGGMHGEASAAAPGARPPPLESLSGCGLGEAL EHPHR*IISHNCSNKRK*WIPSIYAVSQIFQLY CEGPWSRRRMERW*WN**YWRGPESEINERSHG TLC*SR*SGCHVY*ML*CHICWWSRRSSKKIPKG KPQSGLCSRWNFVAR*KTSRQVSCCAHWETLSE FRRIYWLCSICQPYSSTMESPG****SALLH*S LH*STEKGSY*HHIGSQMQNFPDLKWSCR*SCFK I*KWQSQS*EYIL*NITSGN*WKWTHQDSPELF WKLCTQFMDTG*WLHSL*IRYSRLVCSRCPSKR INRCFY*ATNPFSTSVSGHIVDTGLPKRST*TFY S*QRSLS*KGHQGIF**S*A*NQNYKNSRTRRK SKSSGSQKHGNGLLPSG*KV*LLL*CGCRCCFD KSKDFKNFD*TKQKDHCSSCNSSWKAVVQFLGSI ES*WILCTI*RLCGYCSRE*SRSMECPIYG*CV LN*RKDTPIRDE*KELFCS**TGS*YGSLPKC* RNDFTKGKRLPYSGNIPNAQPPKGCIYVHF**T* IWKAIIHC*LQYFPL*Q*PLADF*KSCGLEGKV YKP*LFKDFH*KYS*TALSRCLLVPHIF*KSL* *IGRRNGTLRQMVWGKTS**PYIWWL*KCPN**Y PHEAS*SGECMASFYPGVHCTSYTEGLCRLLYE GICTTEFCSKILP*TTAFSSSSS*CFYIYHKHC T**RGRRLSGRWLQISKVQLLY*VTTKRLELHAS WETHTFA*RTSC*KWNKIHCSVIYRSLSYLLFI ELKFILDE*LA*TRL*SCG*EDERNI*ITSTEQ LHFGPNI*KTFYKKLFDIS*CLL*ALKHRLKKKR KKKLKYLFLCFVASENNDNL*ICVSN**NI*VQ ITRLIIFSYLKKAWEDFYLSKYRGNVDKMDINE NYHVVKP*KSDSNWICMQLSIFLNTYAGLIYSSY *GNTQRITQRFPQENGTKHNRGAYTVENIFVLI GRQIILY*Y*KSNPMFLSDESSKVDYIKQVLDL GKPFHFLKYYQVSRSASVLKSNRFFLLLFLLCFL F*KVLENRKTKNFIEMSSAFNYFLKNFLST*IL YQENKVVEPCFFRFALCLAPYSFFGGRVICFFI FLA*FPFYSSECLC*LPSIPLIKKFSNKNTC*LD VLSLL*VRLKYPYCSYCF*CKG*T*KEILNHGA KIHFLTPCVRKL*KIK*F*K

Frame 2

TALPPDSRRLLLPLPNPLPKLSAGFPVPARSAA *ASTRSRRQLLK*RPR*ANSPDVGPRRAS*GDR TGRAAAAGQPAANSQGAARPVASPRGAYKASAA PRAPAAPCLHRRPHSAALRAAPAAGRAPCPPAPA RNRRLRADPGLCVLARSAALRGRGRLSPRGPRG PNMGGCTVKPQLLLLALVLHPWNPCLGADSEKP SSIPTDKLLVITVATKESDGFHRFMQSAKYFNYT VKVLGQGEEWRGGDGINSIGGGQKVRLMKEVME HYADQDDLVVMFTECFDVIFAGGPEEVLKKFQK ANHKVVFAADGILWPDKRLADKYPVVHIGKRYLN SGGFIGYAPYVNRIVQQWNLQDNDDDQLFYTKV YIDPLKREAINITLDHKCKIFQTLNGAVDEVVL KFENGKARAKNTFYETLPVAINGNGPTKILLNYF GNYVPNSWTQDNGCTLCEFDTVDLSAVDVHPNV SIGVFIEQPTPFLPRFLDILLTLDYPKEALKLF IHNKEVYHEKDIKVFFDKAKHEIKTIKIVGPEEN LSQAEARNMGMDFCRQDEKCDYYFSVDADVVLT NPRTLKILIEQNRKIIAPLVTRHGKLWSNFWGA LSPDGYYARSEDYVDIVQGNRVGVWNVPYMANVY LIKGKTLRSEMNERNYFVRDKLDPDMALCRNAR EMTLQREKDSPTPETFQMLSPPKGVFMYISNRH EFGRLLSTANYNTSHYNNDLWQIFENPVDWKEKY INRDYSKIFTENIVEQPCPDVFWFPIFSEKACD ELVEEMEHYGKWSGGKHHDSRISGGYENVPTDD IHMKQVDLENVWLHFIREFIAPVTLKVFAGYYTK GFALLNFVVKYSPERQRSLRPHHDASTFTINIA LNNVGEDFQGGGCKFLRYNCSIESPRKGWSFMH PGRLTHLHEGLPVKNGTRYIAVSFIDP*VIYFSL N*NLFWMNDWHEHVFEVVAEKMRGIFK*HQQNN FTLGQTFEKLFIKNCLIFLNVCSEP*NTD*RRK ERKNLNIYFYALLPLRIMTIYEFVFQIDKIFRYK *QD**YFLI*KKHGKIFIYQNIEEM*TKWI*MK ITML*NLENQILTGFVCN*VFF*TPMQVLFTVV TKGTHKELHNVFLKKMVQNTTEERIQLKTFLF*L EGRLFYISIKNQTLCFFQMNLPKWIILSRY*I* ENLSIS*SIIKCQDQQVSLSQTGFFCCCFCFVS FFRKF*KIGKRKISLR*VVHLIIF*KTF*VLEFY IRKTKLLSLASSVLPFVSLLILFLGGGLFAFLS SWHNFHFILLSVYVNFPLSRL*KNSPTKILVDL MFYHFSK*G*NILIVATVFNVKVKLEKKFLITVP KFIF*HHVLENYKK*NNFR