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Sequences

Sequence NM_153617

GCGGCCGCTTCCCACCGTCCCTCTCCCCTTACTGGCAGAGCGCGCTGCGGGCGGACTCCCGGGCCCGGAGCAGCCCACCGGCCACCCCACCGCCCACCCG
GCTCCCGGTGTCTCCTCCCGGCCGCTCTACCCAGCAACTTTCCGTGCTTTGTTCCCCGACTGGAAATGCTTTACGGAAGCGTCTTGGACAGGGTCTCCGC
CAGGCGACAAGAGCTCGGTGCTGAGATGTGTTACGTTCTCATCTCCCCATCAATTATGGATGGAAACAAATAAGGAAGAGTCAATTTTGCTGAGCCCCTT
CTCCGGCAACGAGAGGCGTTCTGCAGCCGGGAGGGAGCCGCCGCTCGCGCCGGCAGCCGCTGGCAGGGGCATGGTGAGGAGGAAGGTAGCTCAGTGGCAT
TTCTGAGCAGGGGCCACCCTGACTTCACCTTGGCCCACCATGAGGGTCTTCCTGCTTTGTGCCTACATACTGCTGCTGATGGTTTCCCAGTTGAGGGCAG
TCAGCTTTCCTGAAGATGATGAACCCCTTAATACTGTCGACTATCACTATTCAAGGCAATATCCGGTTTTTAGAGGACGCCCTTCAGGCAATGAATCGCA
GCACAGGCTGGACTTTCAGCTGATGTTGAAAATTCGAGACACACTTTATATTGCTGGCAGGGATCAAGTTTATACAGTAAACTTAAATGAAATGCCCAAA
ACAGAAGTAATACCCAACAAGAAACTGACATGGCGATCAAGACAACAGGATCGAGAAAACTGTGCTATGAAAGGCAAGCATAAAGATGAATGCCACAACT
TTATCAAAGTATTTGTTCCAAGAAACGATGAGATGGTTTTTGTTTGTGGTACCAATGCATTCAATCCCATGTGTAGATACTACAGGTTGAGTACCTTAGA
ATATGATGGGGAAGAAATTAGTGGCCTGGCAAGATGCCCATTTGATGCCAGACAAACCAATGTTGCCCTCTTTGCTGATGGGAAGCTGTATTCTGCCACA
GTGGCTGACTTCTTGGCCAGCGATGCCGTTATTTATCGAAGCATGGGTGATGGATCTGCCCTTCGCACAATAAAATATGATTCCAAATGGATAAAAGAGC
CACACTTTCTTCATGCCATAGAATATGGAAACTATGTCTATTTCTTCTTTCGAGAAATCGCTGTCGAACATAATAATTTAGGCAAGGCTGTGTATTCCCG
CGTGGCCCGCATATGTAAAAACGACATGGGTGGTTCCCAGCGGGTCCTGGAGAAACACTGGACTTCATTTCTAAAGGCTCGGCTGAACTGTTCTGTCCCT
GGAGATTCGTTTTTCTACTTTGATGTTCTGCAGTCTATTACAGACATAATACAAATCAATGGCATCCCCACTGTGGTCGGGGTGTTTACCACGCAGCTCA
ATAGCATCCCTGGTTCTGCTGTCTGTGCATTTAGCATGGATGACATTGAAAAAGTATTCAAAGGACGGTTTAAGGAACAGAAAACTCCAGATTCTGTTTG
GACAGCAGTTCCCGAAGACAAAGTGCCAAAGCCAAGGCCTGGCTGTTGTGCAAAACACGGCCTTGCCGAAGCTTATAAAACCTCCATCGATTTCCCGGAT
GAAACTCTGTCATTCATCAAATCTCATCCCCTGATGGACTCTGCCGTTCCACCCATTGCCGATGAGCCCTGGTTCACAAAGACTCGGGTCAGGTACAGAC
TGACGGCCATCTCAGTGGACCATTCAGCCGGACCCTACCAGAACTACACAGTCATCTTTGTTGGCTCTGAAGCTGGCATGGTACTTAAAGTTCTGGCAAA
GACCAGTCCTTTCTCTTTGAACGACAGCGTATTACTGGAAGAGATTGAAGCCTACAACCATGCAAAGTGCAGTGCTGAGAATGAGGAAGACAAAAAGGTC
ATCTCATTACAGTTGGATAAAGATCACCACGCTTTATATGTGGCGTTCTCTAGCTGCATTATCCGCATCCCCCTCAGTCGCTGTGAGCGTTATGGATCAT
GTAAAAAGTCTTGTATTGCATCTCGTGACCCGTATTGTGGCTGGTTAAGCCAGGGATCCTGTGGTAGAGTGACCCCAGGGATGCTTGCTGAAGGATATGA
ACAAGACACAGAATTCGGCAACACAGCTCATCTAGGGGACTGCCATGAAATTTTGCCTACTTCAACTACACCAGATTACAAAATATTTGGCGGTCCAACA
TC
TGGTGTACGATGGGAAGTCCAGTCTGGAGAGTCCAACCAGATGGTCCACATGAATGTCCTCATCACCTGTGTCTTTGCTGCTTTTGTTTTGGGGGCAT
TCATTGCAGGTGTGGCAGTATACTGCTATCGAGACATGTTTGTTCGGAAAAACAGAAAGATCCATAAAGATGCAGAGTCCGCCCAGTCATGCACAGACTC
CA
GTGGAAGTTTTGCCAAACTGAATGGTCTCTTTGACAGCCCTGTCAAGGAATACCAACAGAATATTGATTCTCCTAAACTGTATAGTAACCTGCTAACC
AGTCGGAAAGAGCTACCACCCAATGGAGATACTAAATCCATGGTAATGGACCATCGAGGGCAACCTCCAGAGTTGGCTGCTCTTCCTACTCCTGAGTCTA
CACCCGTGCTTCACCAGAAGACCCTGCAGGCCATGAAGAGCCACTCAGAAAAGGCCCATGGCCATGGAGCTTCAAGGAAAGAAACCCCTCAGTTTTTTCC
GTCTAGTCCGCCACCTCATTCCCCATTAAGTCATGGGCATATCCCCAGTGCCATTGTTCTTCCAAATGCTACCCATGACTACAACACGTCTTTCTCAAAC
TCCAATGCTCACAAAGCTGAAAAGAAGCTTCAAAACATTGATCACCCTCTCACAAAGTCATCCAGTAAGAGAGATCACCGGCGTTCTGTTGATTCCAGAA
ATACCCTCAATGATCTCCTGAAGCATCTGAATGACCCAAATAGTAACCCCAAAGCCATCATGGGAGACATCCAGATGGCACACCAGAACTTAATGCTGGA
TCCCATGGGATCGATGTCTGAGGTCCCACCTAAAGTCCCTAACCGGGAGGCATCGCTATACTCCCCTCCTTCAACTCTCCCCAGAAATAGCCCAACCAAG
CGAGTGGATGTCCCCACCACTCCTGGAGTCCCAATGACTTCTCTGGAAAGACAAAGAGGTTATCACAAAAATTCCTCCCAGAGGCACTCTATATCTGCTA
TGCCTAAAAACTTAAACTCACCAAATGGTGTTTTGTTATCCAGACAGCCTAGTATGAACCGTGGAGGATATATGCCCACCCCCACTGGGGCGAAGGTGGA
CTATATTCAGGGAACACCAGTGAGTGTTCATCTGCAGCCTTCCCTCTCCAGACAGAGCAGCTACACCAGTAATGGCACTCTTCCTAGGACGGGACTAAAG
AGGACGCCGTCCTTAAAACCTGACGTGCCACCAAAGCCTTCCTTTGTTCCTCAAACCCCATCTGTCAGACCACTGAACAAATACACATACTAGGCCTCAA
GTGTGCTATTCCCATGTGGCTTTATCCTGTCCGTGTTGTTGAGAGGATGATGTTGTAAGGGTACCTTAAAACAAGAGACTCGCTTGTATTTTAAGAGAAC
CAAGTGGCCAAAGAAACTCTTTCTAACTTTGGCAACATCAGAACTTGCCACATGTAGCTACTGCAGCAAGGCTTCTGTGTACTTGCCTGAAAACAAAGGA
AGGTGCTGGTCATTCCATTTCTTTTGTTTGAAGCTAAAGAGATGTGTAGCTCACAGGGGCTACCTTACCAGTATAAAGAGCTGATAACAGTACTCAGAAG
AATCTGTGAACAAATACTTGAAAATGGGTTCAATGTAGACTGCCATTATGTGTGGTCTTCCCATTAAATGTGAACATTTTAATATGTATGCATTCACCTT
GCCTCTTGCACAAATGTCAAAAAAAAGATGGTAATATCTCAAAGAAATGAACTTGTAGATTACCAAGCAGTTTGCTAAAAATTCAATCTTTGACCCAAGC
TGTAGCATTTTTTTTTCATGTGTGGCATCTTTTTCATGCCACCAACAAACTTGTTGTGTGTGTGCGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTT
CTGTACCCACTAGGATTTGTTTAGGTGCCCATTGCATCTTTTTGTGCTATGGAGTTGTTTACATTAAGCATGACCGAACGAGAGACAATACTATTTCCCA
CAGGAGTCCATTGGGTTCAGCTTTGAAAGAGGAATAGAATCGAGGCTCCTTTGACCATCAAAATGATGAACTTTACTTATGTGGTACCCAATGCCAGAAT
GTAAGAGTTGCAAGTGATTTTGTGCTGCTATTCATTAAAACTTGTATTCCAGTCTTGCCAGCTTAAGGAGATCAAGATATTAAGAGGTATCCTTGATTTA
TTTTCCAGTATTCAGTAGTAAAATTTTCCTGTCCACTGTGAATCAAAGCCTGAGTCACTCTATTTAACCTTGGACACACTAATAAGGTTTTATTTTGATT
GTGTTCGTTTCCCCCCCCCCAATAGTAAAATTTCTCCTCCTTTAACTCCTCCTACCCCCCAAGGTAAGAAACAAAAAACAAACAAACAAACAAAAATAGA
AGACAAAAGAAAGACATATGAAAGGAATTGTAATTGGCTTAACAGAAACAGTCTGTAAAAACCTAACAGTGGTGCAATCATGTTGTCTGTGTTGTGTTAT
GTGAGAATTTTCTCCTAAGTCATGCAGGTAATGACAATATACTGTAAATACCACATGTGAGTTTACCTGAATCTGTGCATTTTGTGCCTTATTCATGAGA
ATGATAGAAGTACTAAAATCTGTCAAGTGTTTTCAGTATAGCACATTATTTACTGAGTGCCAGTTGTAAATGTTTTTCAACCAGCACCTAAAAAGACTCT
TTTCAAAAAATCACAGAAACAACCTAGGACAATTATTTGTTACATAATCCGACCTCATAGCAGCATTACATTCTTTGCCGTGATAAACATTCCACTCCTG
CTTTCCTAAGGATGAAACAGTGATAATGTGAACTCAAATGAGGTTTCCTGGGTAATGTGACACCTGCAGAAACTATAGAGCGTCATTTATACGTAGTTTG
GCAGAAACCACTTACGGCTGATGATGCGCAACCCTGCTGACTGTTTCAGTTAATATGCTGCACACCACACACTTGTTTAGTGAACCAAATCTAGAAAGTA
CCAAGGCAGAGGTATGCTCCTGCTGTAATCAGGCAAATGAGTTCAACTGGATTTCTTTTGACAATACTGTTGGTACCTATTACTTGGGGGAGGACATGTT
GCAGAAGACCAGATCATTTTTATACAGAATGTGAAATACTGATACAGTTATTCTTTTTTTTAAAGAACATTGTTTTATAAAGAACGTGATTTCCAGTGAT
CTCTGGAAGCGCTAAAGCTAAAATTTCTGTTCTTGAAACACTTCAGCTTTGCAACTAAAATATTACAGATTAATAATAAATTAAACCAACCAATGATAAA
CACTACTCAGTCCACCAACAACAAACGTGTTTGAATTCACCTTACCAATATTAATCCCAGCGTGTGTAAAACAGAACAGTAACTCTATGTGACCCCAGAT
AACATTTTGTAACATTGTGCTTCCTTGTAGTTTGTAATGTGAGTTCAATCAGTATTTATGTTGAAATTTCTAACATTAAATCTAGTCTCTATCCTGTTAA
TTTAATTTTTAAATGCTTTATCCATTTGTGCAAAGGTAAACGCAGATTGTATCTTTTTTAATGGTACGGCATAAAAAGTAACCCTCAAGTGAAGTGTCTC
TATACTGTTTTATAGAGTACTTTAACATGAATAGATACCTTGTAAACTTGTATTGTGGATGTGTAAATAATATGTACTTTGGGTTTTTAACACCGCATGT
AAAGTCAAAATAAAATATACAAATCATTATA
  • refseq_SEMA6D.F3 (forward primer)
  • refseq_SEMA6D.R3 (reverse primer)
  • Single exon skipping

Frame 0

AAASHRPSPLTGRARCGRTPGPGAAHRPPHRPP
GSRCLLPAALPSNFPCFVPRLEMLYGSVLDRVSA
RRQELGAEMCYVLISPSIMDGNK*GRVNFAEPL
LRQREAFCSREGAAARAGSRWQGHGEEEGSSVA
FLSRGHPDFTLAHHEGLPALCLHTAADGFPVEGS
QLS*R**TP*YCRLSLFKAISGF*RTPFRQ*IA
AQAGLSADVENSRHTLYCWQGSSLYSKLK*NAQ
NRSNTQQETDMAIKTTGSRKLCYERQA*R*MPQL
YQSICSKKR*DGFCLWYQCIQSHV*ILQVEYLR
I*WGRN*WPGKMPI*CQTNQCCPLC*WEAVFCH
SG*LLGQRCRYLSKHG*WICPSHNKI*FQMDKRA
TLSSCHRIWKLCLFLLSRNRCRT**FRQGCVFP
RGPHM*KRHGWFPAGPGETLDFISKGSAELFCP
WRFVFLL*CSAVYYRHNTNQWHPHCGRGVYHAAQ
*HPWFCCLCI*HG*H*KSIQRTV*GTENSRFCL
DSSSRRQSAKAKAWLLCKTRPCRSL*NLHRFPG
*NSVIHQISSPDGLCRSTHCR*ALVHKDSGQVQT
DGHLSGPFSRTLPELHSHLCWL*SWHGT*SSGK
DQSFLFERQRITGRD*SLQPCKVQC*E*GRQKG
HLITVG*RSPRFICGVL*LHYPHPPQSL*ALWIM
*KVLYCIS*PVLWLVKPGILW*SDPRDAC*RI*
TRHRIRQHSSSRGLP*NFAYFNYTRLQNIWRSN
I
WCTMGSPVWRVQPDGPHECPHHLCLCCFCFGGI
HCRCGSILLSRHVCSEKQKDP*RCRVRPVMHRL
Q
WKFCQTEWSL*QPCQGIPTEY*FS*TV**PAN
QSERATTQWRY*IHGNGPSRATSRVGCSSYS*VY
TRASPEDPAGHEEPLRKGPWPWSFKERNPSVFS
V*SATSFPIKSWAYPQCHCSSKCYP*LQHVFLK
LQCSQS*KEASKH*SPSHKVIQ*ERSPAFC*FQK
YPQ*SPEASE*PK**PQSHHGRHPDGTPELNAG
SHGIDV*GPT*SP*PGGIAILPSFNSPQK*PNQ
ASGCPHHSWSPNDFSGKTKRLSQKFLPEALYICY
A*KLKLTKWCFVIQTA*YEPWRIYAHPHWGEGG
LYSGNTSECSSAAFPLQTEQLHQ*WHSS*DGTK
EDAVLKT*RATKAFLCSSNPICQTTEQIHILGLK
CAIPMWLYPVRVVERMML*GYLKTRDSLVF*EN
QVAKETLSNFGNIRTCHM*LLQQGFCVLA*KQR
KVLVIPFLLFEAKEMCSSQGLPYQYKELITVLRR
ICEQILENGFNVDCHYVWSSH*M*TF*YVCIHL
ASCTNVKKKMVISQRNELVDYQAVC*KFNL*PK
L*HFFFMCGIFFMPPTNLLCVCVCVCVCVCVCVF
CTH*DLFRCPLHLFVLWSCLH*A*PNERQYYFP
QESIGFSFERGIESRLL*PSK**TLLMWYPMPE
CKSCK*FCAAIH*NLYSSLASLRRSRY*EVSLIY
FPVFSSKIFLSTVNQSLSHSI*PWTH**GFILI
VFVSPPPIVKFLLL*LLLPPKVRNKKQTNKQK*
KTKERHMKGIVIGLTETVCKNLTVVQSCCLCCVM
*EFSPKSCR**QYTVNTTCEFT*ICAFCALFMR
MIEVLKSVKCFQYSTLFTECQL*MFFNQHLKRL
FSKNHRNNLGQLFVT*SDLIAALHSLP**TFHSC
FPKDETVIM*TQMRFPG*CDTCRNYRASFIRSL
AETTYG**CATLLTVSVNMLHTTHLFSEPNLES
TKAEVCSCCNQANEFNWISFDNTVGTYYLGEDML
QKTRSFLYRM*NTDTVILFFKEHCFIKNVISSD
LWKR*S*NFCS*NTSALQLKYYRLIIN*TNQ**
TLLSPPTTNVFEFTLPILIPACVKQNSNSM*PQI
TFCNIVLPCSL*CEFNQYLC*NF*H*I*SLSC*
FNF*MLYPFVQR*TQIVSFLMVRHKK*PSSEVS
LYCFIEYFNMNRYLVNLYCGCVNNMYFGFLTPHV
KSK*NIQIII

Frame 1

RPLPTVPLPLLAERAAGGLPGPEQPTGHPTAHP
APGVSSRPLYPATFRALFPDWKCFTEASWTGSP
PGDKSSVLRCVTFSSPHQLWMETNKEESILLSPF
SGNERRSAAGREPPLAPAAAGRGMVRRKVAQWH
F*AGATLTSPWPTMRVFLLCAYILLLMVSQLRA
VSFPEDDEPLNTVDYHYSRQYPVFRGRPSGNESQ
HRLDFQLMLKIRDTLYIAGRDQVYTVNLNEMPK
TEVIPNKKLTWRSRQQDRENCAMKGKHKDECHN
FIKVFVPRNDEMVFVCGTNAFNPMCRYYRLSTLE
YDGEEISGLARCPFDARQTNVALFADGKLYSAT
VADFLASDAVIYRSMGDGSALRTIKYDSKWIKE
PHFLHAIEYGNYVYFFFREIAVEHNNLGKAVYSR
VARICKNDMGGSQRVLEKHWTSFLKARLNCSVP
GDSFFYFDVLQSITDIIQINGIPTVVGVFTTQL
NSIPGSAVCAFSMDDIEKVFKGRFKEQKTPDSVW
TAVPEDKVPKPRPGCCAKHGLAEAYKTSIDFPD
ETLSFIKSHPLMDSAVPPIADEPWFTKTRVRYR
LTAISVDHSAGPYQNYTVIFVGSEAGMVLKVLAK
TSPFSLNDSVLLEEIEAYNHAKCSAENEEDKKV
ISLQLDKDHHALYVAFSSCIIRIPLSRCERYGS
CKKSCIASRDPYCGWLSQGSCGRVTPGMLAEGYE
QDTEFGNTAHLGDCHEILPTSTTPDYKIFGGPT
S
GVRWEVQSGESNQMVHMNVLITCVFAAFVLGA
FIAGVAVYCYRDMFVRKNRKIHKDAESAQSCTDS
SGSFAKLNGLFDSPVKEYQQNIDSPKLYSNLLT
SRKELPPNGDTKSMVMDHRGQPPELAALPTPES
TPVLHQKTLQAMKSHSEKAHGHGASRKETPQFFP
SSPPPHSPLSHGHIPSAIVLPNATHDYNTSFSN
SNAHKAEKKLQNIDHPLTKSSSKRDHRRSVDSR
NTLNDLLKHLNDPNSNPKAIMGDIQMAHQNLMLD
PMGSMSEVPPKVPNREASLYSPPSTLPRNSPTK
RVDVPTTPGVPMTSLERQRGYHKNSSQRHSISA
MPKNLNSPNGVLLSRQPSMNRGGYMPTPTGAKVD
YIQGTPVSVHLQPSLSRQSSYTSNGTLPRTGLK
RTPSLKPDVPPKPSFVPQTPSVRPLNKYTY*AS
SVLFPCGFILSVLLRG*CCKGTLKQETRLYFKRT
KWPKKLFLTLATSELATCSYCSKASVYLPENKG
RCWSFHFFCLKLKRCVAHRGYLTSIKS**QYSE
ESVNKYLKMGSM*TAIMCGLPIKCEHFNMYAFTL
PLAQMSKKRW*YLKEMNL*ITKQFAKNSIFDPS
CSIFFSCVASFSCHQQTCCVCACVCVCVCVCVC
SVPTRICLGAHCIFLCYGVVYIKHDRTRDNTISH
RSPLGSALKEE*NRGSFDHQNDELYLCGTQCQN
VRVASDFVLLFIKTCIPVLPA*GDQDIKRYP*F
IFQYSVVKFSCPL*IKA*VTLFNLGHTNKVLF*L
CSFPPPQ**NFSSFNSSYPPR*ETKNKQTNKNR
RQKKDI*KEL*LA*QKQSVKT*QWCNHVVCVVL
CENFLLSHAGNDNIL*IPHVSLPESVHFVPYS*E
**KY*NLSSVFSIAHYLLSASCKCFSTST*KDS
FQKITETT*DNYLLHNPTS*QHYILCRDKHSTP
AFLRMKQ**CELK*GFLGNVTPAETIERHLYVVW
QKPLTADDAQPC*LFQLICCTPHTCLVNQI*KV
PRQRYAPAVIRQMSSTGFLLTILLVPITWGRTC
CRRPDHFYTECEILIQLFFFLKNIVL*RT*FPVI
SGSAKAKISVLETLQLCN*NITD***IKPTNDK
HYSVHQQQTCLNSPYQY*SQRV*NRTVTLCDPR
*HFVTLCFLVVCNVSSISIYVEISNIKSSLYPVN
LIFKCFIHLCKGKRRLYLF*WYGIKSNPQVKCL
YTVL*STLT*IDTL*TCIVDV*IICTLGF*HRM
*SQNKIYKSL

Frame 2

GRFPPSLSPYWQSALRADSRARSSPPATPPPTR
LPVSPPGRSTQQLSVLCSPTGNALRKRLGQGLR
QATRARC*DVLRSHLPINYGWKQIRKSQFC*AP
SPATRGVLQPGGSRRSRRQPLAGAW*GGR*LSGI
SEQGPP*LHLGPP*GSSCFVPTYCC*WFPS*GQ
SAFLKMMNPLILSTITIQGNIRFLEDALQAMNR
STGWTFS*C*KFETHFILLAGIKFIQ*T*MKCPK
QK*YPTRN*HGDQDNRIEKTVL*KASIKMNATT
LSKYLFQETMRWFLFVVPMHSIPCVDTTG*VP*
NMMGKKLVAWQDAHLMPDKPMLPSLLMGSCILPQ
WLTSWPAMPLFIEAWVMDLPFAQ*NMIPNG*KS
HTFFMP*NMETMSISSFEKSLSNIII*ARLCIP
AWPAYVKTTWVVPSGSWRNTGLHF*RLG*TVLSL
EIRFSTLMFCSLLQT*YKSMASPLWSGCLPRSS
IASLVLLSVHLAWMTLKKYSKDGLRNRKLQILF
GQQFPKTKCQSQGLAVVQNTALPKLIKPPSISRM
KLCHSSNLIP*WTLPFHPLPMSPGSQRLGSGTD
*RPSQWTIQPDPTRTTQSSLLALKLAWYLKFWQ
RPVLSL*TTAYYWKRLKPTTMQSAVLRMRKTKRS
SHYSWIKITTLYMWRSLAALSASPSVAVSVMDH
VKSLVLHLVTRIVAG*ARDPVVE*PQGCLLKDM
NKTQNSATQLI*GTAMKFCLLQLHQITKYLAVQH
LVYDGKSSLESPTRWST*MSSSPVSLLLLFWGH
SLQVWQYTAIETCLFGKTERSIKMQSPPSHAQT
P
VEVLPN*MVSLTALSRNTNRILILLNCIVTC*P
VGKSYHPMEILNPW*WTIEGNLQSWLLFLLLSL
HPCFTRRPCRP*RATQKRPMAMELQGKKPLSFF
RLVRHLIPH*VMGISPVPLFFQMLPMTTTRLSQT
PMLTKLKRSFKTLITLSQSHPVREITGVLLIPE
IPSMIS*SI*MTQIVTPKPSWETSRWHTRT*CW
IPWDRCLRSHLKSLTGRHRYTPLLQLSPEIAQPS
EWMSPPLLESQ*LLWKDKEVITKIPPRGTLYLL
CLKT*THQMVFCYPDSLV*TVEDICPPPLGRRW
TIFREHQ*VFICSLPSPDRAATPVMALFLGRD*R
GRRP*NLTCHQSLPLFLKPHLSDH*TNTHTRPQ
VCYSHVALSCPCC*EDDVVRVP*NKRLACILRE
PSGQRNSF*LWQHQNLPHVATAARLLCTCLKTKE
GAGHSISFV*S*RDV*LTGATLPV*RADNSTQK
NL*TNT*KWVQCRLPLCVVFPLNVNILICMHSP
CLLHKCQKKDGNISKK*TCRLPSSLLKIQSLTQA
VAFFFHVWHLFHATNKLVVCVRVCVCVCVCVCV
LYPLGFV*VPIASFCAMELFTLSMTERETILFP
TGVHWVQL*KRNRIEAPLTIKMMNFTYVVPNARM
*ELQVILCCYSLKLVFQSCQLKEIKILRGILDL
FSSIQ**NFPVHCESKPESLYLTLDTLIRFYFD
CVRFPPPNSKISPPLTPPTPQGKKQKTNKQTKIE
DKRKTYERNCNWLNRNSL*KPNSGAIMLSVLCY
VRIFS*VMQVMTIYCKYHM*VYLNLCILCLIHE
NDRSTKICQVFSV*HIIY*VPVVNVFQPAPKKTL
FKKSQKQPRTIICYIIRPHSSITFFAVINIPLL
LS*G*NSDNVNSNEVSWVM*HLQKL*SVIYT*F
GRNHLRLMMRNPADCFS*YAAHHTLV**TKSRKY
QGRGMLLL*SGK*VQLDFF*QYCWYLLLGGGHV
AEDQIIFIQNVKY*YSYSFF*RTLFYKERDFQ*
SLEALKLKFLFLKHFSFATKILQINNKLNQPMIN
TTQSTNNKRV*IHLTNINPSVCKTEQ*LYVTPD
NIL*HCASL*FVM*VQSVFMLKFLTLNLVSILL
I*FLNALSICAKVNADCIFFNGTA*KVTLK*SVS
ILFYRVL*HE*IPCKLVLWMCK*YVLWVFNTAC
KVKIKYTNHY

Sequence NM_153618

GCGGCCGCTTCCCACCGTCCCTCTCCCCTTACTGGCAGAGCGCGCTGCGGGCGGACTCCCGGGCCCGGAGCAGCCCACCGGCCACCCCACCGCCCACCCG
GCTCCCGGTGTCTCCTCCCGGCCGCTCTACCCAGCAACTTTCCGTGCTTTGTTCCCCGACTGGAAATGCTTTACGGAAGCGTCTTGGACAGGGTCTCCGC
CAGGCGACAAGAGCTCGGTGCTGAGATGTGTTACGTTCTCATCTCCCCATCAATTATGGATGGAAACAAATAAGGAAGAGTCAATTTTGCTGAGCCCCTT
CTCCGGCAACGAGAGGCGTTCTGCAGCCGGGAGGGAGCCGCCGCTCGCGCCGGCAGCCGCTGGCAGGGGCATGGTGAGGAGGAAGGTAGCTCAGTGGCAT
TTCTGAGCAGGGGCCACCCTGACTTCACCTTGGCCCACCATGAGGGTCTTCCTGCTTTGTGCCTACATACTGCTGCTGATGGTTTCCCAGTTGAGGGCAG
TCAGCTTTCCTGAAGATGATGAACCCCTTAATACTGTCGACTATCACTATTCAAGGCAATATCCGGTTTTTAGAGGACGCCCTTCAGGCAATGAATCGCA
GCACAGGCTGGACTTTCAGCTGATGTTGAAAATTCGAGACACACTTTATATTGCTGGCAGGGATCAAGTTTATACAGTAAACTTAAATGAAATGCCCAAA
ACAGAAGTAATACCCAACAAGAAACTGACATGGCGATCAAGACAACAGGATCGAGAAAACTGTGCTATGAAAGGCAAGCATAAAGATGAATGCCACAACT
TTATCAAAGTATTTGTTCCAAGAAACGATGAGATGGTTTTTGTTTGTGGTACCAATGCATTCAATCCCATGTGTAGATACTACAGGTTGAGTACCTTAGA
ATATGATGGGGAAGAAATTAGTGGCCTGGCAAGATGCCCATTTGATGCCAGACAAACCAATGTTGCCCTCTTTGCTGATGGGAAGCTGTATTCTGCCACA
GTGGCTGACTTCTTGGCCAGCGATGCCGTTATTTATCGAAGCATGGGTGATGGATCTGCCCTTCGCACAATAAAATATGATTCCAAATGGATAAAAGAGC
CACACTTTCTTCATGCCATAGAATATGGAAACTATGTCTATTTCTTCTTTCGAGAAATCGCTGTCGAACATAATAATTTAGGCAAGGCTGTGTATTCCCG
CGTGGCCCGCATATGTAAAAACGACATGGGTGGTTCCCAGCGGGTCCTGGAGAAACACTGGACTTCATTTCTAAAGGCTCGGCTGAACTGTTCTGTCCCT
GGAGATTCGTTTTTCTACTTTGATGTTCTGCAGTCTATTACAGACATAATACAAATCAATGGCATCCCCACTGTGGTCGGGGTGTTTACCACGCAGCTCA
ATAGCATCCCTGGTTCTGCTGTCTGTGCATTTAGCATGGATGACATTGAAAAAGTATTCAAAGGACGGTTTAAGGAACAGAAAACTCCAGATTCTGTTTG
GACAGCAGTTCCCGAAGACAAAGTGCCAAAGCCAAGGCCTGGCTGTTGTGCAAAACACGGCCTTGCCGAAGCTTATAAAACCTCCATCGATTTCCCGGAT
GAAACTCTGTCATTCATCAAATCTCATCCCCTGATGGACTCTGCCGTTCCACCCATTGCCGATGAGCCCTGGTTCACAAAGACTCGGGTCAGGTACAGAC
TGACGGCCATCTCAGTGGACCATTCAGCCGGACCCTACCAGAACTACACAGTCATCTTTGTTGGCTCTGAAGCTGGCATGGTACTTAAAGTTCTGGCAAA
GACCAGTCCTTTCTCTTTGAACGACAGCGTATTACTGGAAGAGATTGAAGCCTACAACCATGCAAAGTGCAGTGCTGAGAATGAGGAAGACAAAAAGGTC
ATCTCATTACAGTTGGATAAAGATCACCACGCTTTATATGTGGCGTTCTCTAGCTGCATTATCCGCATCCCCCTCAGTCGCTGTGAGCGTTATGGATCAT
GTAAAAAGTCTTGTATTGCATCTCGTGACCCGTATTGTGGCTGGTTAAGCCAGGGATCCTGTGGTAGAGTGACCCCAGGGATGCTTGCTGAAGGATATGA
ACAAGACACAGAATTCGGCAACACAGCTCATCTAGGGGACTGCCATGAAATTTTGCCTACTTCAACTACACCAGATTACAAAATATTTGGCGGTCCAACA
TC
TGACATGGAGGTATCTTCATCTTCTGTTACCACAATGGCAAGTATCCCAGAAATCACACCTAAAGTGATTGATACCTGGAGACCTAAACTGACAAGCT
CTCGGAAATTTGTAGTTCAAGATGATCCAAACACTTCTGATTTTACTGATCCTTTATCGGGTATCCCAAAGG
GTGTACGATGGGAAGTCCAGTCTGGAGA
GTCCAACCAGATGGTCCACATGAATGTCCTCATCACCTGTGTCTTTGCTGCTTTTGTTTTGGGGGCATTCATTGCAGGTGTGGCAGTATACTGCTATCGA
GACATGTTTGTTCGGAAAAACAGAAAGATCCATAAAGATGCAGAGTCCGCCCAGTCATGCACAGACTCCAGTGGAAGTTTTGCCAAACTGAATGGTCTCT
TTGACAGCCCTGTCAAGGAATACCAACAGAATATTGATTCTCCTAAACTGTATAGTAACCTGCTAACCAGTCGGAAAGAGCTACCACCCAATGGAGATAC
TAAATCCATGGTAATGGACCATCGAGGGCAACCTCCAGAGTTGGCTGCTCTTCCTACTCCTGAGTCTACACCCGTGCTTCACCAGAAGACCCTGCAGGCC
ATGAAGAGCCACTCAGAAAAGGCCCATGGCCATGGAGCTTCAAGGAAAGAAACCCCTCAGTTTTTTCCGTCTAGTCCGCCACCTCATTCCCCATTAAGTC
ATGGGCATATCCCCAGTGCCATTGTTCTTCCAAATGCTACCCATGACTACAACACGTCTTTCTCAAACTCCAATGCTCACAAAGCTGAAAAGAAGCTTCA
AAACATTGATCACCCTCTCACAAAGTCATCCAGTAAGAGAGATCACCGGCGTTCTGTTGATTCCAGAAATACCCTCAATGATCTCCTGAAGCATCTGAAT
GACCCAAATAGTAACCCCAAAGCCATCATGGGAGACATCCAGATGGCACACCAGAACTTAATGCTGGATCCCATGGGATCGATGTCTGAGGTCCCACCTA
AAGTCCCTAACCGGGAGGCATCGCTATACTCCCCTCCTTCAACTCTCCCCAGAAATAGCCCAACCAAGCGAGTGGATGTCCCCACCACTCCTGGAGTCCC
AATGACTTCTCTGGAAAGACAAAGAGGTTATCACAAAAATTCCTCCCAGAGGCACTCTATATCTGCTATGCCTAAAAACTTAAACTCACCAAATGGTGTT
TTGTTATCCAGACAGCCTAGTATGAACCGTGGAGGATATATGCCCACCCCCACTGGGGCGAAGGTGGACTATATTCAGGGAACACCAGTGAGTGTTCATC
TGCAGCCTTCCCTCTCCAGACAGAGCAGCTACACCAGTAATGGCACTCTTCCTAGGACGGGACTAAAGAGGACGCCGTCCTTAAAACCTGACGTGCCACC
AAAGCCTTCCTTTGTTCCTCAAACCCCATCTGTCAGACCACTGAACAAATACACATACTAGGCCTCAAGTGTGCTATTCCCATGTGGCTTTATCCTGTCC
GTGTTGTTGAGAGGATGATGTTGTAAGGGTACCTTAAAACAAGAGACTCGCTTGTATTTTAAGAGAACCAAGTGGCCAAAGAAACTCTTTCTAACTTTGG
CAACATCAGAACTTGCCACATGTAGCTACTGCAGCAAGGCTTCTGTGTACTTGCCTGAAAACAAAGGAAGGTGCTGGTCATTCCATTTCTTTTGTTTGAA
GCTAAAGAGATGTGTAGCTCACAGGGGCTACCTTACCAGTATAAAGAGCTGATAACAGTACTCAGAAGAATCTGTGAACAAATACTTGAAAATGGGTTCA
ATGTAGACTGCCATTATGTGTGGTCTTCCCATTAAATGTGAACATTTTAATATGTATGCATTCACCTTGCCTCTTGCACAAATGTCAAAAAAAAGATGGT
AATATCTCAAAGAAATGAACTTGTAGATTACCAAGCAGTTTGCTAAAAATTCAATCTTTGACCCAAGCTGTAGCATTTTTTTTTCATGTGTGGCATCTTT
TTCATGCCACCAACAAACTTGTTGTGTGTGTGCGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTTCTGTACCCACTAGGATTTGTTTAGGTGCCCAT
TGCATCTTTTTGTGCTATGGAGTTGTTTACATTAAGCATGACCGAACGAGAGACAATACTATTTCCCACAGGAGTCCATTGGGTTCAGCTTTGAAAGAGG
AATAGAATCGAGGCTCCTTTGACCATCAAAATGATGAACTTTACTTATGTGGTACCCAATGCCAGAATGTAAGAGTTGCAAGTGATTTTGTGCTGCTATT
CATTAAAACTTGTATTCCAGTCTTGCCAGCTTAAGGAGATCAAGATATTAAGAGGTATCCTTGATTTATTTTCCAGTATTCAGTAGTAAAATTTTCCTGT
CCACTGTGAATCAAAGCCTGAGTCACTCTATTTAACCTTGGACACACTAATAAGGTTTTATTTTGATTGTGTTCGTTTCCCCCCCCCCAATAGTAAAATT
TCTCCTCCTTTAACTCCTCCTACCCCCCAAGGTAAGAAACAAAAAACAAACAAACAAACAAAAATAGAAGACAAAAGAAAGACATATGAAAGGAATTGTA
ATTGGCTTAACAGAAACAGTCTGTAAAAACCTAACAGTGGTGCAATCATGTTGTCTGTGTTGTGTTATGTGAGAATTTTCTCCTAAGTCATGCAGGTAAT
GACAATATACTGTAAATACCACATGTGAGTTTACCTGAATCTGTGCATTTTGTGCCTTATTCATGAGAATGATAGAAGTACTAAAATCTGTCAAGTGTTT
TCAGTATAGCACATTATTTACTGAGTGCCAGTTGTAAATGTTTTTCAACCAGCACCTAAAAAGACTCTTTTCAAAAAATCACAGAAACAACCTAGGACAA
TTATTTGTTACATAATCCGACCTCATAGCAGCATTACATTCTTTGCCGTGATAAACATTCCACTCCTGCTTTCCTAAGGATGAAACAGTGATAATGTGAA
CTCAAATGAGGTTTCCTGGGTAATGTGACACCTGCAGAAACTATAGAGCGTCATTTATACGTAGTTTGGCAGAAACCACTTACGGCTGATGATGCGCAAC
CCTGCTGACTGTTTCAGTTAATATGCTGCACACCACACACTTGTTTAGTGAACCAAATCTAGAAAGTACCAAGGCAGAGGTATGCTCCTGCTGTAATCAG
GCAAATGAGTTCAACTGGATTTCTTTTGACAATACTGTTGGTACCTATTACTTGGGGGAGGACATGTTGCAGAAGACCAGATCATTTTTATACAGAATGT
GAAATACTGATACAGTTATTCTTTTTTTTAAAGAACATTGTTTTATAAAGAACGTGATTTCCAGTGATCTCTGGAAGCGCTAAAGCTAAAATTTCTGTTC
TTGAAACACTTCAGCTTTGCAACTAAAATATTACAGATTAATAATAAATTAAACCAACCAATGATAAACACTACTCAGTCCACCAACAACAAACGTGTTT
GAATTCACCTTACCAATATTAATCCCAGCGTGTGTAAAACAGAACAGTAACTCTATGTGACCCCAGATAACATTTTGTAACATTGTGCTTCCTTGTAGTT
TGTAATGTGAGTTCAATCAGTATTTATGTTGAAATTTCTAACATTAAATCTAGTCTCTATCCTGTTAATTTAATTTTTAAATGCTTTATCCATTTGTGCA
AAGGTAAACGCAGATTGTATCTTTTTTAATGGTACGGCATAAAAAGTAACCCTCAAGTGAAGTGTCTCTATACTGTTTTATAGAGTACTTTAACATGAAT
AGATACCTTGTAAACTTGTATTGTGGATGTGTAAATAATATGTACTTTGGGTTTTTAACACCGCATGTAAAGTCAAAATAAAATATACAAATCATTATA
  • refseq_SEMA6D.F3 (forward primer)
  • refseq_SEMA6D.R3 (reverse primer)
  • Single exon skipping

Frame 0

AAASHRPSPLTGRARCGRTPGPGAAHRPPHRPP
GSRCLLPAALPSNFPCFVPRLEMLYGSVLDRVSA
RRQELGAEMCYVLISPSIMDGNK*GRVNFAEPL
LRQREAFCSREGAAARAGSRWQGHGEEEGSSVA
FLSRGHPDFTLAHHEGLPALCLHTAADGFPVEGS
QLS*R**TP*YCRLSLFKAISGF*RTPFRQ*IA
AQAGLSADVENSRHTLYCWQGSSLYSKLK*NAQ
NRSNTQQETDMAIKTTGSRKLCYERQA*R*MPQL
YQSICSKKR*DGFCLWYQCIQSHV*ILQVEYLR
I*WGRN*WPGKMPI*CQTNQCCPLC*WEAVFCH
SG*LLGQRCRYLSKHG*WICPSHNKI*FQMDKRA
TLSSCHRIWKLCLFLLSRNRCRT**FRQGCVFP
RGPHM*KRHGWFPAGPGETLDFISKGSAELFCP
WRFVFLL*CSAVYYRHNTNQWHPHCGRGVYHAAQ
*HPWFCCLCI*HG*H*KSIQRTV*GTENSRFCL
DSSSRRQSAKAKAWLLCKTRPCRSL*NLHRFPG
*NSVIHQISSPDGLCRSTHCR*ALVHKDSGQVQT
DGHLSGPFSRTLPELHSHLCWL*SWHGT*SSGK
DQSFLFERQRITGRD*SLQPCKVQC*E*GRQKG
HLITVG*RSPRFICGVL*LHYPHPPQSL*ALWIM
*KVLYCIS*PVLWLVKPGILW*SDPRDAC*RI*
TRHRIRQHSSSRGLP*NFAYFNYTRLQNIWRSN
I
*HGGIFIFCYHNGKYPRNHT*SD*YLET*TDKL
SEICSSR*SKHF*FY*SFIGYPKG
CTMGSPVWR
VQPDGPHECPHHLCLCCFCFGGIHCRCGSILLS
RHVCSEKQKDP*RCRVRPVMHRLQWKFCQTEWSL
*QPCQGIPTEY*FS*TV**PANQSERATTQWRY
*IHGNGPSRATSRVGCSSYS*VYTRASPEDPAG
HEEPLRKGPWPWSFKERNPSVFSV*SATSFPIKS
WAYPQCHCSSKCYP*LQHVFLKLQCSQS*KEAS
KH*SPSHKVIQ*ERSPAFC*FQKYPQ*SPEASE
*PK**PQSHHGRHPDGTPELNAGSHGIDV*GPT*
SP*PGGIAILPSFNSPQK*PNQASGCPHHSWSP
NDFSGKTKRLSQKFLPEALYICYA*KLKLTKWC
FVIQTA*YEPWRIYAHPHWGEGGLYSGNTSECSS
AAFPLQTEQLHQ*WHSS*DGTKEDAVLKT*RAT
KAFLCSSNPICQTTEQIHILGLKCAIPMWLYPV
RVVERMML*GYLKTRDSLVF*ENQVAKETLSNFG
NIRTCHM*LLQQGFCVLA*KQRKVLVIPFLLFE
AKEMCSSQGLPYQYKELITVLRRICEQILENGF
NVDCHYVWSSH*M*TF*YVCIHLASCTNVKKKMV
ISQRNELVDYQAVC*KFNL*PKL*HFFFMCGIF
FMPPTNLLCVCVCVCVCVCVCVFCTH*DLFRCP
LHLFVLWSCLH*A*PNERQYYFPQESIGFSFERG
IESRLL*PSK**TLLMWYPMPECKSCK*FCAAI
H*NLYSSLASLRRSRY*EVSLIYFPVFSSKIFL
STVNQSLSHSI*PWTH**GFILIVFVSPPPIVKF
LLL*LLLPPKVRNKKQTNKQK*KTKERHMKGIV
IGLTETVCKNLTVVQSCCLCCVM*EFSPKSCR*
*QYTVNTTCEFT*ICAFCALFMRMIEVLKSVKCF
QYSTLFTECQL*MFFNQHLKRLFSKNHRNNLGQ
LFVT*SDLIAALHSLP**TFHSCFPKDETVIM*
TQMRFPG*CDTCRNYRASFIRSLAETTYG**CAT
LLTVSVNMLHTTHLFSEPNLESTKAEVCSCCNQ
ANEFNWISFDNTVGTYYLGEDMLQKTRSFLYRM
*NTDTVILFFKEHCFIKNVISSDLWKR*S*NFCS
*NTSALQLKYYRLIIN*TNQ**TLLSPPTTNVF
EFTLPILIPACVKQNSNSM*PQITFCNIVLPCS
L*CEFNQYLC*NF*H*I*SLSC*FNF*MLYPFVQ
R*TQIVSFLMVRHKK*PSSEVSLYCFIEYFNMN
RYLVNLYCGCVNNMYFGFLTPHVKSK*NIQIII

Frame 1

RPLPTVPLPLLAERAAGGLPGPEQPTGHPTAHP
APGVSSRPLYPATFRALFPDWKCFTEASWTGSP
PGDKSSVLRCVTFSSPHQLWMETNKEESILLSPF
SGNERRSAAGREPPLAPAAAGRGMVRRKVAQWH
F*AGATLTSPWPTMRVFLLCAYILLLMVSQLRA
VSFPEDDEPLNTVDYHYSRQYPVFRGRPSGNESQ
HRLDFQLMLKIRDTLYIAGRDQVYTVNLNEMPK
TEVIPNKKLTWRSRQQDRENCAMKGKHKDECHN
FIKVFVPRNDEMVFVCGTNAFNPMCRYYRLSTLE
YDGEEISGLARCPFDARQTNVALFADGKLYSAT
VADFLASDAVIYRSMGDGSALRTIKYDSKWIKE
PHFLHAIEYGNYVYFFFREIAVEHNNLGKAVYSR
VARICKNDMGGSQRVLEKHWTSFLKARLNCSVP
GDSFFYFDVLQSITDIIQINGIPTVVGVFTTQL
NSIPGSAVCAFSMDDIEKVFKGRFKEQKTPDSVW
TAVPEDKVPKPRPGCCAKHGLAEAYKTSIDFPD
ETLSFIKSHPLMDSAVPPIADEPWFTKTRVRYR
LTAISVDHSAGPYQNYTVIFVGSEAGMVLKVLAK
TSPFSLNDSVLLEEIEAYNHAKCSAENEEDKKV
ISLQLDKDHHALYVAFSSCIIRIPLSRCERYGS
CKKSCIASRDPYCGWLSQGSCGRVTPGMLAEGYE
QDTEFGNTAHLGDCHEILPTSTTPDYKIFGGPT
S
DMEVSSSSVTTMASIPEITPKVIDTWRPKLTS
SRKFVVQDDPNTSDFTDPLSGIPK
GVRWEVQSGE
SNQMVHMNVLITCVFAAFVLGAFIAGVAVYCYR
DMFVRKNRKIHKDAESAQSCTDSSGSFAKLNGL
FDSPVKEYQQNIDSPKLYSNLLTSRKELPPNGDT
KSMVMDHRGQPPELAALPTPESTPVLHQKTLQA
MKSHSEKAHGHGASRKETPQFFPSSPPPHSPLS
HGHIPSAIVLPNATHDYNTSFSNSNAHKAEKKLQ
NIDHPLTKSSSKRDHRRSVDSRNTLNDLLKHLN
DPNSNPKAIMGDIQMAHQNLMLDPMGSMSEVPP
KVPNREASLYSPPSTLPRNSPTKRVDVPTTPGVP
MTSLERQRGYHKNSSQRHSISAMPKNLNSPNGV
LLSRQPSMNRGGYMPTPTGAKVDYIQGTPVSVH
LQPSLSRQSSYTSNGTLPRTGLKRTPSLKPDVPP
KPSFVPQTPSVRPLNKYTY*ASSVLFPCGFILS
VLLRG*CCKGTLKQETRLYFKRTKWPKKLFLTL
ATSELATCSYCSKASVYLPENKGRCWSFHFFCLK
LKRCVAHRGYLTSIKS**QYSEESVNKYLKMGS
M*TAIMCGLPIKCEHFNMYAFTLPLAQMSKKRW
*YLKEMNL*ITKQFAKNSIFDPSCSIFFSCVASF
SCHQQTCCVCACVCVCVCVCVCSVPTRICLGAH
CIFLCYGVVYIKHDRTRDNTISHRSPLGSALKE
E*NRGSFDHQNDELYLCGTQCQNVRVASDFVLLF
IKTCIPVLPA*GDQDIKRYP*FIFQYSVVKFSC
PL*IKA*VTLFNLGHTNKVLF*LCSFPPPQ**N
FSSFNSSYPPR*ETKNKQTNKNRRQKKDI*KEL*
LA*QKQSVKT*QWCNHVVCVVLCENFLLSHAGN
DNIL*IPHVSLPESVHFVPYS*E**KY*NLSSV
FSIAHYLLSASCKCFSTST*KDSFQKITETT*DN
YLLHNPTS*QHYILCRDKHSTPAFLRMKQ**CE
LK*GFLGNVTPAETIERHLYVVWQKPLTADDAQ
PC*LFQLICCTPHTCLVNQI*KVPRQRYAPAVIR
QMSSTGFLLTILLVPITWGRTCCRRPDHFYTEC
EILIQLFFFLKNIVL*RT*FPVISGSAKAKISV
LETLQLCN*NITD***IKPTNDKHYSVHQQQTCL
NSPYQY*SQRV*NRTVTLCDPR*HFVTLCFLVV
CNVSSISIYVEISNIKSSLYPVNLIFKCFIHLC
KGKRRLYLF*WYGIKSNPQVKCLYTVL*STLT*I
DTL*TCIVDV*IICTLGF*HRM*SQNKIYKSL

Frame 2

GRFPPSLSPYWQSALRADSRARSSPPATPPPTR
LPVSPPGRSTQQLSVLCSPTGNALRKRLGQGLR
QATRARC*DVLRSHLPINYGWKQIRKSQFC*AP
SPATRGVLQPGGSRRSRRQPLAGAW*GGR*LSGI
SEQGPP*LHLGPP*GSSCFVPTYCC*WFPS*GQ
SAFLKMMNPLILSTITIQGNIRFLEDALQAMNR
STGWTFS*C*KFETHFILLAGIKFIQ*T*MKCPK
QK*YPTRN*HGDQDNRIEKTVL*KASIKMNATT
LSKYLFQETMRWFLFVVPMHSIPCVDTTG*VP*
NMMGKKLVAWQDAHLMPDKPMLPSLLMGSCILPQ
WLTSWPAMPLFIEAWVMDLPFAQ*NMIPNG*KS
HTFFMP*NMETMSISSFEKSLSNIII*ARLCIP
AWPAYVKTTWVVPSGSWRNTGLHF*RLG*TVLSL
EIRFSTLMFCSLLQT*YKSMASPLWSGCLPRSS
IASLVLLSVHLAWMTLKKYSKDGLRNRKLQILF
GQQFPKTKCQSQGLAVVQNTALPKLIKPPSISRM
KLCHSSNLIP*WTLPFHPLPMSPGSQRLGSGTD
*RPSQWTIQPDPTRTTQSSLLALKLAWYLKFWQ
RPVLSL*TTAYYWKRLKPTTMQSAVLRMRKTKRS
SHYSWIKITTLYMWRSLAALSASPSVAVSVMDH
VKSLVLHLVTRIVAG*ARDPVVE*PQGCLLKDM
NKTQNSATQLI*GTAMKFCLLQLHQITKYLAVQH
LTWRYLHLLLPQWQVSQKSHLK*LIPGDLN*QA
LGNL*FKMIQTLLILLILYRVSQR
VYDGKSSLE
SPTRWST*MSSSPVSLLLLFWGHSLQVWQYTAIE
TCLFGKTERSIKMQSPPSHAQTPVEVLPN*MVS
LTALSRNTNRILILLNCIVTC*PVGKSYHPMEI
LNPW*WTIEGNLQSWLLFLLLSLHPCFTRRPCRP
*RATQKRPMAMELQGKKPLSFFRLVRHLIPH*V
MGISPVPLFFQMLPMTTTRLSQTPMLTKLKRSF
KTLITLSQSHPVREITGVLLIPEIPSMIS*SI*M
TQIVTPKPSWETSRWHTRT*CWIPWDRCLRSHL
KSLTGRHRYTPLLQLSPEIAQPSEWMSPPLLES
Q*LLWKDKEVITKIPPRGTLYLLCLKT*THQMVF
CYPDSLV*TVEDICPPPLGRRWTIFREHQ*VFI
CSLPSPDRAATPVMALFLGRD*RGRRP*NLTCH
QSLPLFLKPHLSDH*TNTHTRPQVCYSHVALSCP
CC*EDDVVRVP*NKRLACILREPSGQRNSF*LW
QHQNLPHVATAARLLCTCLKTKEGAGHSISFV*
S*RDV*LTGATLPV*RADNSTQKNL*TNT*KWVQ
CRLPLCVVFPLNVNILICMHSPCLLHKCQKKDG
NISKK*TCRLPSSLLKIQSLTQAVAFFFHVWHL
FHATNKLVVCVRVCVCVCVCVCVLYPLGFV*VPI
ASFCAMELFTLSMTERETILFPTGVHWVQL*KR
NRIEAPLTIKMMNFTYVVPNARM*ELQVILCCY
SLKLVFQSCQLKEIKILRGILDLFSSIQ**NFPV
HCESKPESLYLTLDTLIRFYFDCVRFPPPNSKI
SPPLTPPTPQGKKQKTNKQTKIEDKRKTYERNC
NWLNRNSL*KPNSGAIMLSVLCYVRIFS*VMQVM
TIYCKYHM*VYLNLCILCLIHENDRSTKICQVF
SV*HIIY*VPVVNVFQPAPKKTLFKKSQKQPRT
IICYIIRPHSSITFFAVINIPLLLS*G*NSDNVN
SNEVSWVM*HLQKL*SVIYT*FGRNHLRLMMRN
PADCFS*YAAHHTLV**TKSRKYQGRGMLLL*S
GK*VQLDFF*QYCWYLLLGGGHVAEDQIIFIQNV
KY*YSYSFF*RTLFYKERDFQ*SLEALKLKFLF
LKHFSFATKILQINNKLNQPMINTTQSTNNKRV
*IHLTNINPSVCKTEQ*LYVTPDNIL*HCASL*F
VM*VQSVFMLKFLTLNLVSILLI*FLNALSICA
KVNADCIFFNGTA*KVTLK*SVSILFYRVL*HE
*IPCKLVLWMCK*YVLWVFNTACKVKIKYTNHY

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