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Sequences

Sequence DNMT1.iAug05

CCCAGCCCCAGCCGCGGCCGCCCTGGGGACGCAGACGCCAAGGCCCCTCCGGCCAGGGCCGGGAGCCGGGCCGGCCTAGCCAGGCTCAAAGATTTGGAAA
GAGACAGCTTAACAGAAAAGGAATGTGTGAAGGAGAAATTGAATCTCTTGCACGAATTTCTGCAAACAGAAATAAAGAATCAGTTATGTGACTTGGAAAC
CA
AATTACGTAAAGAAGAATTATCCGAGGAGGGCTACCTGGCTAAAGTCAAATCCCTTTTAAATAAAGATTTGTCCTTGGAGAACGGTGCTCATGCTTAC
AACCGGGAAGTGAATGGACGTCTAGAAAACGGGAACCAAGCAAGAAGTGAAGCCCGTAGAGTGGGAATGGCAGATGCCAACAGCCCCCCCAAACCCCTTT
CCAAACCTCGCACGCCCAGGAGGAGCAAGTCCGATGGAGAGGCTAAGCGTTCAAGAGACCCTCCTGCCTCAGCCTCCCAAGTAACTGGGATTAGAGCTGA
ACCTTCACCTAGCCCCAGGATTACAAGGAAAAGCACCAGGCAAACCACCATCACATCTCATTTTGCAAAGGGCCCTGCCAAACGGAAACCTCAGGAAGAG
TCTGAAAGAGCCAAATCGGATGAGTCCATCAAGGAAGAAGACAAAGACC
  • DNMT1.u.f.1 (forward primer)
  • DNMT1.u.r.9 (reverse primer)
  • Single exon skipping

Frame 0

PSPSRGRPGDADAKAPPARAGSRAGLARLKDLE
RDSLTEKECVKEKLNLLHEFLQTEIKNQLCDLET
KLRKEELSEEGYLAKVKSLLNKDLSLENGAHAY
NREVNGRLENGNQARSEARRVGMADANSPPKPL
SKPRTPRRSKSDGEAKRSRDPPASASQVTGIRAE
PSPSPRITRKSTRQTTITSHFAKGPAKRKPQEE
SERAKSDESIKEEDKD

Frame 1

PAPAAAALGTQTPRPLRPGPGAGPA*PGSKIWK
ETA*QKRNV*RRN*ISCTNFCKQK*RISYVTWK
P
NYVKKNYPRRATWLKSNPF*IKICPWRTVLMLT
TGK*MDV*KTGTKQEVKPVEWEWQMPTAPPNPF
PNLARPGGASPMERLSVQETLLPQPPK*LGLEL
NLHLAPGLQGKAPGKPPSHLILQRALPNGNLRKS
LKEPNRMSPSRKKTKT

Frame 2

QPQPRPPWGRRRQGPSGQGREPGRPSQAQRFGK
RQLNRKGMCEGEIESLARISANRNKESVM*LGN
Q
IT*RRIIRGGLPG*SQIPFK*RFVLGERCSCL
QPGSEWTSRKREPSKK*SP*SGNGRCQQPPQTPF
QTSHAQEEQVRWRG*AFKRPSCLSLPSNWD*S*
TFT*PQDYKEKHQANHHHISFCKGPCQTETSGR
V*KSQIG*VHQGRRQR

Sequence DNMT1.jAug05

CCCAGCCCCAGCCGCGGCCGCCCTGGGGACGCAGACGCCAAGGCCCCTCCGGCCAGGGCCGGGAGCCGGGCCGGCCTAGCCAGGGTCTGACTCTGTCACC
CAGGCTGGAGTGCAGTGACGTAATCACAGCTCACCGCAGCCTTGACCTCCTGGGCTCAAGCCATCCTCCCACCTCAATCTCCCAAGTAGGTGGAACTACA
G
GCTCAAAGATTTGGAAAGAGACAGCTTAACAGAAAAGGAATGTGTGAAGGAGAAATTGAATCTCTTGCACGAATTTCTGCAAACAGAAATAAAGAATCA
GTTATGTGACTTGGAAACCA
AATTACGTAAAGAAGAATTATCCGAGGAGGGCTACCTGGCTAAAGTCAAATCCCTTTTAAATAAAGATTTGTCCTTGGAG
AACGGTGCTCATGCTTACAACCGGGAAGTGAATGGACGTCTAGAAAACGGGAACCAAGCAAGAAGTGAAGCCCGTAGAGTGGGAATGGCAGATGCCAACA
GCCCCCCCAAACCCCTTTCCAAACCTCGCACGCCCAGGAGGAGCAAGTCCGATGGAGAGGCTAAGCCTGAACCTTCACCTAGCCCCAGGATTACAAGGAA
AAGCACCAGGCAAACCACCATCACATCTCATTTTGCAAAGGGCCCTGCCAAACGGAAACCTCAGGAAGAGTCTGAAAGAGCCAAATCGGATGAGTCCATC
AAGGAAGAAGACAAAGACCAGGATGAGAAGAGACGTAGAGTTACATCCAGAGAACG
  • DNMT1.u.f.1 (forward primer)
  • DNMT1.u.r.9 (reverse primer)
  • Single exon skipping

Frame 0

PSPSRGRPGDADAKAPPARAGSRAGLARV*LCH
PGWSAVT*SQLTAALTSWAQAILPPQSPK*VELQ
AQRFGKRQLNRKGMCEGEIESLARISANRNKES
VM*LGNQ
IT*RRIIRGGLPG*SQIPFK*RFVLG
ERCSCLQPGSEWTSRKREPSKK*SP*SGNGRCQQ
PPQTPFQTSHAQEEQVRWRG*A*TFT*PQDYKE
KHQANHHHISFCKGPCQTETSGRV*KSQIG*VH
QGRRQRPG*EET*SYIQRT

Frame 1

PAPAAAALGTQTPRPLRPGPGAGPA*PGSDSVT
QAGVQ*RNHSSPQP*PPGLKPSSHLNLPSRWNY
R
LKDLERDSLTEKECVKEKLNLLHEFLQTEIKNQ
LCDLET
KLRKEELSEEGYLAKVKSLLNKDLSLE
NGAHAYNREVNGRLENGNQARSEARRVGMADAN
SPPKPLSKPRTPRRSKSDGEAKPEPSPSPRITRK
STRQTTITSHFAKGPAKRKPQEESERAKSDESI
KEEDKDQDEKRRRVTSRE

Frame 2

QPQPRPPWGRRRQGPSGQGREPGRPSQGLTLSP
RLECSDVITAHRSLDLLGSSHPPTSISQVGGTT
GSKIWKETA*QKRNV*RRN*ISCTNFCKQK*RI
SYVTWKP
NYVKKNYPRRATWLKSNPF*IKICPWR
TVLMLTTGK*MDV*KTGTKQEVKPVEWEWQMPT
APPNPFPNLARPGGASPMERLSLNLHLAPGLQG
KAPGKPPSHLILQRALPNGNLRKSLKEPNRMSPS
RKKTKTRMRRDVELHPEN

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