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Sequences

Sequence OGG1.qAug05

ACATCGCCCGCATCACTGGCATGGTGGAGCGGCTGTGCCAGGCTTTTGGACCTCGGCTCATCCAGCTTGATGATGTCACCTACCATGGCTTCCCCAGCCT
GCAGGCCCTGGCTGGAAACTTTTTCCGGAGCCTGTGGGGACCTTATGCTGGCTGGGCCCAAGCGGTGAGTGTACCTAGGTGTCCTCCCTAGGTTTCCTCT
CCTCCAGCCCAGACCCAGTGGACTCTTCCACCACCGCCCCAGGTGGCCCTAAAGGACTCTCCAGCCACCCCTGTCCCAACCCCAGTGGATTCTCATTGCC
TTCGGCCCTGTTCCCCAAGGACTCTTCCACCTCCCAACACTGTCACTAGTCTCACCAGCCCTGACCCCAGTGTACCCTCCTCCCCACACAGACTCCACCC
TCCTACAGGTGCTGTTCAGTGCCGACCTGCGCCAATCCCGCCATGCTCAGGAGCCACCAGCAAAGCGCAGAAAGGGTTCCAAAGGGCCGGAAGGCTAGAT
GGGGCACCCTGGACAAAGAAATTCCCCAAGCACCTTCCCCTCCATTCCCCACTTCTCTCTCCCCATCCCCACCCAGTCTCATGTTGGGGAGGGGCCTCCC
TGTGACTACCTCAAAGGCCAGGCACCCCCAAATCAAGCAGTCAGTTTGCACAACAAGATGGGGTGGGGGATATTGAGGGAGACAGCGCTAAGGATGGTTT
TATCTTCCCTTTATTACAAGAAGGAACAATAAAATAGAAACATTTGTATGGA
  • OGG1.u.f.12 (forward primer)
  • OGG1.u.r.14 (reverse primer)
  • Multiple exon skipping

Frame 0

TSPASLAWWSGCARLLDLGSSSLMMSPTMASPA
CRPWLETFSGACGDLMLAGPKR*VYLGVLPRFPL
LQPRPSGLFHHRPRWP*RTLQPPLSQPQWILIA
FGPVPQGLFHLPTLSLVSPALTPVYPPPHTDST
LLQVLFSADLRQSRHAQEPPAKRRKGSKGPEG*M
GHPGQRNSPSTFPSIPHFSLPIPTQSHVGEGPP
CDYLKGQAPPNQAVSLHNKMGWGILRETALRMV
LSSLYYKKEQ*NRNICM

Frame 1

HRPHHWHGGAAVPGFWTSAHPA**CHLPWLPQP
AGPGWKLFPEPVGTLCWLGPSGECT*VSSLGFL
SSSPDPVDSSTTAPGGPKGLSSHPCPNPSGFSLP
SALFPKDSSTSQHCH*SHQP*PQCTLLPTQTPP
SYRCCSVPTCANPAMLRSHQQSAERVPKGRKAR
WGTLDKEIPQAPSPPFPTSLSPSPPSLMLGRGLP
VTTSKARHPQIKQSVCTTRWGGGY*GRQR*GWF
YLPFITRRNNKIETFVW

Frame 2

IARITGMVERLCQAFGPRLIQLDDVTYHGFPSL
QALAGNFFRSLWGPYAGWAQAVSVPRCPP*VSS
PPAQTQWTLPPPPQVALKDSPATPVPTPVDSHC
LRPCSPRTLPPPNTVTSLTSPDPSVPSSPHRLHP
PTGAVQCRPAPIPPCSGATSKAQKGFQRAGRLD
GAPWTKKFPKHLPLHSPLLSPHPHPVSCWGGAS
L*LPQRPGTPKSSSQFAQQDGVGDIEGDSAKDGF
IFPLLQEGTIK*KHLYG

Sequence OGG1.iAug05

ATCGCTTGAACCCGGGAGGCGGAGCTTGCAGTGAGCCGAGATCGCGCCATCACACTCCAGCCTAGGCGACAGAGTGAGACTCCGTCTCAAAGAAAAAAAA
CTTGCAGCCTGATAGTTAAGATACAGCAACCCCAAATCCCTATGCTAAAAGGTGAGAATGGCCCAGATAAAGGTCATGTCTCCTAGCTCCCTGCTTTTTC
ATGCCATCCTCCAGAAGGGAAGAAATTAAATAATCCATCCTCCTACTCCAGGCGACTAGAAGGCAGGCTGCCTCAGGGCCACACACTGGGACTTGGACTC
AACCTGATGGGCTTCTGGGCCCAGCCCCAGACAAACCCCCGGCAAACGTCCCATTCCGAGGAAAGCATGAGCAGATGGAGTATGGAAGAAATGCCCAAGA
CGGCAGGCAGCAGCTGTGGCGGCCGGCGGGACGACAATCCGAGGAGAGGCCTCTGATGTCCTGAGGTCTCAGAGGACGCCTAAAGGCCTTGAATGGGACA
AGCTTAGCGGGCGGGCGCAGAAGAGAATAATACTCTGGAGACACTTCCCGAGGGCTCTGGGGCCGGAGCTGTGTTCGCTCCGGTTCTTGGTGAAGACAGG
GTTCGTGGGAGGCGGCCCAAGGAGGGCGAACGCCTAAGACTGCAAAGGCTCGGGGGAGAACGGCTCTCGGAGAACGGGCTGGGGAAGGACGTGGCTCTGA
AGACGGACAGCCCTGAGGAACCGCGGGGCGCCCAGATGGAACTCGTTAGCGCCCCGAGTGCAGACAATCCCGGAGGGGGAAAGGCGAGCAGCTGGCAGAG
AGCCCAGTGCCGGCCAACCGCGCGAGCGCCTCAGAACGGCCCGCCCACCCTGATTTCTCATTGGCGCCTCCTACCTCCTCCTCGGATTGGCTACCTCTAG
GTGAAATGAGCGGTGGTTGAGCCCTACTTCCGGTGGTGCTGTGGTCTGCCCCTGGAGAACCCAGAAGAACACAGCTGTGCGCGCCCACAGGCTCTGGGGG
CGGGAGAAGATAAGTCGCAAGGAGGGGGCGGGACCTACACCTCAGGAAAGCCGGAGAATTGGGGCACGAAGCGGGGCTTTGATGACCCGCAAAGGGCGAG
GCATGCAGGAGGTGGAGGAATTAAGTGAAACAGGGAAGGTTGTTAAACAGCACCGTGTGGGCGAGGCCTTAAGGGTCGTGGTCCTTGTCTGGGCGGGGTC
TTTGGGCGTCGACGAGGCCTGGTTCTGGGTAGGCGGGGCTACTACGGGGCGGTGCCTGCTGTGGAAATGCCTGCCCGCGCGCTTCTGCCCAGGCGCATGG
GGCATCGTACTCTAGCCTCCACTCCTGCCCTGTGGGCCTCCATCCCGTGCCCTCGCTCTGAGCTGCGCCTGGACCTGGTTCTGCCTTCTGGACAATCTTT
CCGGTGTGCGACTGCTGCGACAAGACCCCATCGAATGCCTTTTCTCTTTTATCTGTTCCTCCAACAACAACATCGCCCGCATCACTGGCATGGTGGAGCG
GCTGTGCCAGGCTTTTGGACCTCGGCTCATCCAGCTTGATGATGTCACCTACCATGGCTTCCCCAGCCTGCAGGCCCTGGCTGGGCCAGAGGTGGAGGCT
CATCTCAGGAAGCTGGGCCTGGGCTATCGTGCCCGTTACGTGAGTGCCAGTGCCCGAGCCATCCTGGAAGAACAGGGCGGGCTAGCCTGGCTGCAGCAGC
TACGAGAGTCCTCATATGAGGAGGCCCACAAGGCCCTCTGCATCCTGCCTGGAGTGGGCACCAAGGTGGCTGACTGCATCTGCCTGATGGCCCTAGACAA
GCCCCAGGCTGTGCCCGTGGATGTCCATATGTGGCACATTGCCCAACGTGACTACAGCTGGCACCCTACCACGTCCCAGGCGAAGGGACCGAGCCCCCAG
ACCAACAAGGAACTGG
GAAACTTTTTCCGGAGCCTGTGGGGACCTTATGCTGGCTGGGCCCAAGCGGTGAGTGTACCTAGGTGTCCTCCCTAGGTTTCCT
CTCCTCCAGCCCAGACCCAGTGGACTCTTCCACCACCGCCCCAGGTGGCCCTAAAGGACTCTCCAGCCACCCCTGTCCCAACCCCAGTGGATTCTCATTG
CCTTCGGCCCTGTTCCCCAAGGACTCTTCCACCTCCCAACACTGTCACTAGTCTCACCAGCCCTGACCCCAGTGTACCCTCCTCCCCACACAGACTCCAC
CCTCCTACAGGTGCTGTTCAGTGCCGACCTGCGCCAATCCCGCCATGCTCAGGAGCCACCAGCAAAGCGCAGAAAGGGTTCCAAAGGGCCGGAAGGCTAG
ATGGGGCACCCTGGACAAAGAAATTCCCCAAGCACCTTCCCCTCCATTCCCCACTTCTCTCTCCCCATCCCCACCCAGTCTCATGTTGGGGAGGGGCCTC
CCTGTGACTACCTCAAAGGCCAGGCACCCCCAAATCAAGCAGTCAGTTTGCACAACAAGATGGGGTGGGGGATATTGAGGGAGACAGCGCTAAGGATGGT
TTTATCTTCCCTTTATTACAAGAAGGAACAATAAAATAGAAACATTTGTATGGA
  • OGG1.u.f.12 (forward primer)
  • OGG1.u.r.14 (reverse primer)
  • Multiple exon skipping

Frame 0

IA*TREAELAVSRDRAITLQPRRQSETPSQRKK
TCSLIVKIQQPQIPMLKGENGPDKGHVS*LPAFS
CHPPEGKKLNNPSSYSRRLEGRLPQGHTLGLGL
NLMGFWAQPQTNPRQTSHSEESMSRWSMEEMPK
TAGSSCGGRRDDNPRRGL*CPEVSEDA*RP*MGQ
A*RAGAEENNTLETLPEGSGAGAVFAPVLGEDR
VRGRRPKEGERLRLQRLGGERLSENGLGKDVAL
KTDSPEEPRGAQMELVSAPSADNPGGGKASSWQR
AQCRPTARAPQNGPPTLISHWRLLPPPRIGYL*
VK*AVVEPYFRWCCGLPLENPEEHSCARPQALG
AGEDKSQGGGGTYTSGKPENWGTKRGFDDPQRAR
HAGGGGIK*NREGC*TAPCGRGLKGRGPCLGGV
FGRRRGLVLGRRGYYGAVPAVEMPARALLPRRM
GHRTLASTPALWASIPCPRSELRLDLVLPSGQSF
RCATAATRPHRMPFLFYLFLQQQHRPHHWHGGA
AVPGFWTSAHPA**CHLPWLPQPAGPGWARGGG
SSQEAGPGLSCPLRECQCPSHPGRTGRASLAAAA
TRVLI*GGPQGPLHPAWSGHQGG*LHLPDGPRQ
APGCARGCPYVAHCPT*LQLAPYHVPGEGTEPP
DQQGTG
KLFPEPVGTLCWLGPSGECT*VSSLGFL
SSSPDPVDSSTTAPGGPKGLSSHPCPNPSGFSL
PSALFPKDSSTSQHCH*SHQP*PQCTLLPTQTP
PSYRCCSVPTCANPAMLRSHQQSAERVPKGRKAR
WGTLDKEIPQAPSPPFPTSLSPSPPSLMLGRGL
PVTTSKARHPQIKQSVCTTRWGGGY*GRQR*GW
FYLPFITRRNNKIETFVW

Frame 1

SLEPGRRSLQ*AEIAPSHSSLGDRVRLRLKEKK
LAA**LRYSNPKSLC*KVRMAQIKVMSPSSLLF
HAILQKGRN*IIHPPTPGD*KAGCLRATHWDLDS
T*WASGPSPRQTPGKRPIPRKA*ADGVWKKCPR
RQAAAVAAGGTTIRGEASDVLRSQRTPKGLEWD
KLSGRAQKRIILWRHFPRALGPELCSLRFLVKTG
FVGGGPRRANA*DCKGSGENGSRRTGWGRTWL*
RRTALRNRGAPRWNSLAPRVQTIPEGERRAAGR
EPSAGQPRERLRTARPP*FLIGASYLLLGLATSR
*NERWLSPTSGGAVVCPWRTQKNTAVRAHRLWG
REKISRKEGAGPTPQESRRIGARSGALMTRKGR
GMQEVEELSETGKVVKQHRVGEALRVVVLVWAGS
LGVDEAWFWVGGATTGRCLLWKCLPARFCPGAW
GIVL*PPLLPCGPPSRALALSCAWTWFCLLDNL
SGVRLLRQDPIECLFSFICSSNNNIARITGMVER
LCQAFGPRLIQLDDVTYHGFPSLQALAGPEVEA
HLRKLGLGYRARYVSASARAILEEQGGLAWLQQ
LRESSYEEAHKALCILPGVGTKVADCICLMALDK
PQAVPVDVHMWHIAQRDYSWHPTTSQAKGPSPQ
TNKEL
GNFFRSLWGPYAGWAQAVSVPRCPP*VS
SPPAQTQWTLPPPPQVALKDSPATPVPTPVDSHC
LRPCSPRTLPPPNTVTSLTSPDPSVPSSPHRLH
PPTGAVQCRPAPIPPCSGATSKAQKGFQRAGRL
DGAPWTKKFPKHLPLHSPLLSPHPHPVSCWGGAS
L*LPQRPGTPKSSSQFAQQDGVGDIEGDSAKDG
FIFPLLQEGTIK*KHLYG

Frame 2

RLNPGGGACSEPRSRHHTPA*ATE*DSVSKKKN
LQPDS*DTATPNPYAKR*EWPR*RSCLLAPCFF
MPSSRREEIK*SILLLQATRRQAASGPHTGTWT
QPDGLLGPAPDKPPANVPFRGKHEQMEYGRNAQD
GRQQLWRPAGRQSEERPLMS*GLRGRLKALNGT
SLAGGRRRE*YSGDTSRGLWGRSCVRSGSW*RQ
GSWEAAQGGRTPKTAKARGRTALGERAGEGRGSE
DGQP*GTAGRPDGTR*RPECRQSRRGKGEQLAE
SPVPANRASASERPAHPDFSLAPPTSSSDWLPL
GEMSGG*ALLPVVLWSAPGEPRRTQLCAPTGSGG
GRR*VARRGRDLHLRKAGELGHEAGL**PAKGE
ACRRWRN*VKQGRLLNSTVWARP*GSWSLSGRG
LWASTRPGSG*AGLLRGGACCGNACPRASAQAHG
ASYSSLHSCPVGLHPVPSL*AAPGPGSAFWTIF
PVCDCCDKTPSNAFSLLSVPPTTTSPASLAWWS
GCARLLDLGSSSLMMSPTMASPACRPWLGQRWRL
ISGSWAWAIVPVT*VPVPEPSWKNRAG*PGCSS
YESPHMRRPTRPSASCLEWAPRWLTASA*WP*T
SPRLCPWMSICGTLPNVTTAGTLPRPRRRDRAPR
PTRNW
ETFSGACGDLMLAGPKR*VYLGVLPRFP
LLQPRPSGLFHHRPRWP*RTLQPPLSQPQWILI
AFGPVPQGLFHLPTLSLVSPALTPVYPPPHTDST
LLQVLFSADLRQSRHAQEPPAKRRKGSKGPEG*
MGHPGQRNSPSTFPSIPHFSLPIPTQSHVGEGP
PCDYLKGQAPPNQAVSLHNKMGWGILRETALRMV
LSSLYYKKEQ*NRNICM

Sequence OGG1.fAug05

ATCGCTTGAACCCGGGAGGCGGAGCTTGCAGTGAGCCGAGATCGCGCCATCACACTCCAGCCTAGGCGACAGAGTGAGACTCCGTCTCAAAGAAAAAAAA
CTTGCAGCCTGATAGTTAAGATACAGCAACCCCAAATCCCTATGCTAAAAGGTGAGAATGGCCCAGATAAAGGTCATGTCTCCTAGCTCCCTGCTTTTTC
ATGCCATCCTCCAGAAGGGAAGAAATTAAATAATCCATCCTCCTACTCCAGGCGACTAGAAGGCAGGCTGCCTCAGGGCCACACACTGGGACTTGGACTC
AACCTGATGGGCTTCTGGGCCCAGCCCCAGACAAACCCCCGGCAAACGTCCCATTCCGAGGAAAGCATGAGCAGATGGAGTATGGAAGAAATGCCCAAGA
CGGCAGGCAGCAGCTGTGGCGGCCGGCGGGACGACAATCCGAGGAGAGGCCTCTGATGTCCTGAGGTCTCAGAGGACGCCTAAAGGCCTTGAATGGGACA
AGCTTAGCGGGCGGGCGCAGAAGAGAATAATACTCTGGAGACACTTCCCGAGGGCTCTGGGGCCGGAGCTGTGTTCGCTCCGGTTCTTGGTGAAGACAGG
GTTCGTGGGAGGCGGCCCAAGGAGGGCGAACGCCTAAGACTGCAAAGGCTCGGGGGAGAACGGCTCTCGGAGAACGGGCTGGGGAAGGACGTGGCTCTGA
AGACGGACAGCCCTGAGGAACCGCGGGGCGCCCAGATGGAACTCGTTAGCGCCCCGAGTGCAGACAATCCCGGAGGGGGAAAGGCGAGCAGCTGGCAGAG
AGCCCAGTGCCGGCCAACCGCGCGAGCGCCTCAGAACGGCCCGCCCACCCTGATTTCTCATTGGCGCCTCCTACCTCCTCCTCGGATTGGCTACCTCTAG
GTGAAATGAGCGGTGGTTGAGCCCTACTTCCGGTGGTGCTGTGGTCTGCCCCTGGAGAACCCAGAAGAACACAGCTGTGCGCGCCCACAGGCTCTGGGGG
CGGGAGAAGATAAGTCGCAAGGAGGGGGCGGGACCTACACCTCAGGAAAGCCGGAGAATTGGGGCACGAAGCGGGGCTTTGATGACCCGCAAAGGGCGAG
GCATGCAGGAGGTGGAGGAATTAAGTGAAACAGGGAAGGTTGTTAAACAGCACCGTGTGGGCGAGGCCTTAAGGGTCGTGGTCCTTGTCTGGGCGGGGTC
TTTGGGCGTCGACGAGGCCTGGTTCTGGGTAGGCGGGGCTACTACGGGGCGGTGCCTGCTGTGGAAATGCCTGCCCGCGCGCTTCTGCCCAGGCGCATGG
GGCATCGTACTCTAGCCTCCACTCCTGCCCTGTGGGCCTCCATCCCGTGCCCTCGCTCTGAGCTGCGCCTGGACCTGGTTCTGCCTTCTGGACAATCTTT
CCGGTGGAGGGAGCAAAGTCCTGCACACTGGAGTGGTGTACTAGCGGATCAAGTATGGACACTGACTCAGACTGAGGAGCAGCTCCACTGCACTGTGTAC
CGAGGAGACAAGAGCCAGGCTAGCAGGCCCACACCAGACGAGCTGGAGGCCGTGCGCAAGTACTTCCAGCTAGATGTTACCCTGGCTCAACTGTATCACC
ACTGGGGTTCCGTGGACTCCCACTTCCAAGAGGTGGCTCAGAAATTCCAAGGTGTGCGACTGCTGCGACAAGACCCCATCGAATGCCTTTTCTCTTTTAT
CTGTTCCTCCAACAACAACATCGCCCGCATCACTGGCATGGTGGAGCGGCTGTGCCAGGCTTTTGGACCTCGGCTCATCCAGCTTGATGATGTCACCTAC
CATGGCTTCC
CCAGCCTGCAGGCCCTGGCTGGGCCAGAGGTGGAGGCTCATCTCAGGAAGCTGGGCCTGGGCTATCGTGCCCGTTACGTGAGTGCCAGTG
CCCGAGCCATCCTGGAAGAACAGGGCGGGCTAGCCTGGCTGCAGCAGCTACGAGAGTCCTCATATGAGGAGGCCCACAAGGCCCTCTGCATCCTGCCTGG
AGTGGGCACCAAGGTGGCTGACTGCATCTGCCTGATGGCCCTAGACAAGCCCCAGGCTGTGCCCGTGGATGTCCATATGTGGCACATTGCCCAACGTGAC
TACAGCTGGCACCCTACCACGTCCCAGGCGAAGGGACCGAGCCCCCAGACCAACAAGGAACTGG
GAAACTTTTTCCGGAGCCTGTGGGGACCTTATGCTG
GCTGGGCCCAAGCGGTGAGTGTACCTAGGTGTCCTCCCTAGGTTTCCTCTCCTCCAGCCCAGACCCAGTGGACTCTTCCACCACCGCCCCAGGTGGCCCT
AAAGGACTCTCCAGCCACCCCTGTCCCAACCCCAGTGGATTCTCATTGCCTTCGGCCCTGTTCCCCAAGGACTCTTCCACCTCCCAACACTGTCACTAGT
CTCACCAGCCCTGACCCCAGTGTACCCTCCTCCCCACACAGACTCCACCCTCCTACAGGTGCTGTTCAGTGCCGACCTGCGCCAATCCCGCCATGCTCAG
GAGCCACCAGCAAAGCGCAGAAAGGGTTCCAAAGGGCCGGAAGGCTAGATGGGGCACCCTGGACAAAGAAATTCCCCAAGCACCTTCCCCTCCATTCCCC
ACTTCTCTCTCCCCATCCCCACCCAGTCTCATGTTGGGGAGGGGCCTCCCTGTGACTACCTCAAAGGCCAGGCACCCCCAAATCAAGCAGTCAGTTTGCA
CAACAAGATGGGGTGGGGGATATTGAGGGAGACAGCGCTAAGGATGGTTTTATCTTCCCTTTATTACAAGAAGGAACAATAAAATAGAAACATTTGTATG
GA
  • OGG1.u.f.12 (forward primer)
  • OGG1.u.r.14 (reverse primer)
  • Multiple exon skipping

Frame 0

IA*TREAELAVSRDRAITLQPRRQSETPSQRKK
TCSLIVKIQQPQIPMLKGENGPDKGHVS*LPAFS
CHPPEGKKLNNPSSYSRRLEGRLPQGHTLGLGL
NLMGFWAQPQTNPRQTSHSEESMSRWSMEEMPK
TAGSSCGGRRDDNPRRGL*CPEVSEDA*RP*MGQ
A*RAGAEENNTLETLPEGSGAGAVFAPVLGEDR
VRGRRPKEGERLRLQRLGGERLSENGLGKDVAL
KTDSPEEPRGAQMELVSAPSADNPGGGKASSWQR
AQCRPTARAPQNGPPTLISHWRLLPPPRIGYL*
VK*AVVEPYFRWCCGLPLENPEEHSCARPQALG
AGEDKSQGGGGTYTSGKPENWGTKRGFDDPQRAR
HAGGGGIK*NREGC*TAPCGRGLKGRGPCLGGV
FGRRRGLVLGRRGYYGAVPAVEMPARALLPRRM
GHRTLASTPALWASIPCPRSELRLDLVLPSGQSF
RWREQSPAHWSGVLADQVWTLTQTEEQLHCTVY
RGDKSQASRPTPDELEAVRKYFQLDVTLAQLYH
HWGSVDSHFQEVAQKFQGVRLLRQDPIECLFSFI
CSSNNNIARITGMVERLCQAFGPRLIQLDDVTY
HGF
PSLQALAGPEVEAHLRKLGLGYRARYVSAS
ARAILEEQGGLAWLQQLRESSYEEAHKALCILPG
VGTKVADCICLMALDKPQAVPVDVHMWHIAQRD
YSWHPTTSQAKGPSPQTNKEL
GNFFRSLWGPYA
GWAQAVSVPRCPP*VSSPPAQTQWTLPPPPQVAL
KDSPATPVPTPVDSHCLRPCSPRTLPPPNTVTS
LTSPDPSVPSSPHRLHPPTGAVQCRPAPIPPCS
GATSKAQKGFQRAGRLDGAPWTKKFPKHLPLHSP
LLSPHPHPVSCWGGASL*LPQRPGTPKSSSQFA
QQDGVGDIEGDSAKDGFIFPLLQEGTIK*KHLY
G

Frame 1

SLEPGRRSLQ*AEIAPSHSSLGDRVRLRLKEKK
LAA**LRYSNPKSLC*KVRMAQIKVMSPSSLLF
HAILQKGRN*IIHPPTPGD*KAGCLRATHWDLDS
T*WASGPSPRQTPGKRPIPRKA*ADGVWKKCPR
RQAAAVAAGGTTIRGEASDVLRSQRTPKGLEWD
KLSGRAQKRIILWRHFPRALGPELCSLRFLVKTG
FVGGGPRRANA*DCKGSGENGSRRTGWGRTWL*
RRTALRNRGAPRWNSLAPRVQTIPEGERRAAGR
EPSAGQPRERLRTARPP*FLIGASYLLLGLATSR
*NERWLSPTSGGAVVCPWRTQKNTAVRAHRLWG
REKISRKEGAGPTPQESRRIGARSGALMTRKGR
GMQEVEELSETGKVVKQHRVGEALRVVVLVWAGS
LGVDEAWFWVGGATTGRCLLWKCLPARFCPGAW
GIVL*PPLLPCGPPSRALALSCAWTWFCLLDNL
SGGGSKVLHTGVVY*RIKYGH*LRLRSSSTALCT
EETRARLAGPHQTSWRPCASTSS*MLPWLNCIT
TGVPWTPTSKRWLRNSKVCDCCDKTPSNAFSLL
SVPPTTTSPASLAWWSGCARLLDLGSSSLMMSPT
MAS
PACRPWLGQRWRLISGSWAWAIVPVT*VPV
PEPSWKNRAG*PGCSSYESPHMRRPTRPSASCL
EWAPRWLTASA*WP*TSPRLCPWMSICGTLPNVT
TAGTLPRPRRRDRAPRPTRNW
ETFSGACGDLML
AGPKR*VYLGVLPRFPLLQPRPSGLFHHRPRWP
*RTLQPPLSQPQWILIAFGPVPQGLFHLPTLSLV
SPALTPVYPPPHTDSTLLQVLFSADLRQSRHAQ
EPPAKRRKGSKGPEG*MGHPGQRNSPSTFPSIP
HFSLPIPTQSHVGEGPPCDYLKGQAPPNQAVSLH
NKMGWGILRETALRMVLSSLYYKKEQ*NRNICM

Frame 2

RLNPGGGACSEPRSRHHTPA*ATE*DSVSKKKN
LQPDS*DTATPNPYAKR*EWPR*RSCLLAPCFF
MPSSRREEIK*SILLLQATRRQAASGPHTGTWT
QPDGLLGPAPDKPPANVPFRGKHEQMEYGRNAQD
GRQQLWRPAGRQSEERPLMS*GLRGRLKALNGT
SLAGGRRRE*YSGDTSRGLWGRSCVRSGSW*RQ
GSWEAAQGGRTPKTAKARGRTALGERAGEGRGSE
DGQP*GTAGRPDGTR*RPECRQSRRGKGEQLAE
SPVPANRASASERPAHPDFSLAPPTSSSDWLPL
GEMSGG*ALLPVVLWSAPGEPRRTQLCAPTGSGG
GRR*VARRGRDLHLRKAGELGHEAGL**PAKGE
ACRRWRN*VKQGRLLNSTVWARP*GSWSLSGRG
LWASTRPGSG*AGLLRGGACCGNACPRASAQAHG
ASYSSLHSCPVGLHPVPSL*AAPGPGSAFWTIF
PVEGAKSCTLEWCTSGSSMDTDSD*GAAPLHCV
PRRQEPG*QAHTRRAGGRAQVLPARCYPGSTVSP
LGFRGLPLPRGGSEIPRCATAATRPHRMPFLFY
LFLQQQHRPHHWHGGAAVPGFWTSAHPA**CHL
PWLP
QPAGPGWARGGGSSQEAGPGLSCPLRECQC
PSHPGRTGRASLAAAATRVLI*GGPQGPLHPAW
SGHQGG*LHLPDGPRQAPGCARGCPYVAHCPT*
LQLAPYHVPGEGTEPPDQQGTG
KLFPEPVGTLCW
LGPSGECT*VSSLGFLSSSPDPVDSSTTAPGGP
KGLSSHPCPNPSGFSLPSALFPKDSSTSQHCH*
SHQP*PQCTLLPTQTPPSYRCCSVPTCANPAMLR
SHQQSAERVPKGRKARWGTLDKEIPQAPSPPFP
TSLSPSPPSLMLGRGLPVTTSKARHPQIKQSVC
TTRWGGGY*GRQR*GWFYLPFITRRNNKIETFVW

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