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Sequences

Sequence BOK.dAug05

GCCCCAAGCCCAGCCTCTCGCCAGCTGGGAGTCGCGCGCTGCCCACCTCGCTGCCCAGGCCCCCGACGCCGCGGCAGGAGCCCCCCAAGAGCGCGGGAAG CCCCGTGGACCTGGCGCTCCCGGCTCGGGCGTGGACGGGGCGGGCGCCGGGGCGGGGCGCGCGTCCTCGCGGGTCTGAATGGAAGGGTCGAGGTCGTCGT CGGCGGCGAGCAGATCCTGAAGCCAGAACTCCACCCCGGCGCCCGCGCCATGCGGCGGGAGAGGTGCGGCGCCCCCCACCCGCGTCGCCGCCATGGAGGT GCTGCGGCGCTCCTCGGTCTTCGCCGCCGAGATCATGGACGCCTTTGACCGCTCGCCCACAGACAAGGAGCTGGTGGCCCAGGCCAAGGCGCTGGGCCGG GAGTACGTGCACGCGCGGCTGCTGCGCGCCGGCCTCTCCTGGAGCGCGCCCGAGCGTGCCGCGCCGGTCCCGGGACGCCTGGCTGAGGTGTGCGCGGTGC TGCTGCGCCTGGGCATCACGTGGGGCAAGGTGGTGTCCCTGTATGCGGTGGCCGCGGGGCTGGCCGTGGACTGTGTGAGGCAGGCCCAGCCTGCCATGGT CCACGCCCTCGTGGACTGCCTGGGGGAGTTCGTGCGCAAGACCCTGGCAACCTGGCTGCGGAGACGCGGCGGATGGACTGATGTCCTCAAGTGTGTGGTC AGCACAGACCCTGGCCTCCGCTCCCACTGGCTGGTGGCTGCACTCTGCAGCTTCGGCCGCTTCCTGAAGGCTGCCTTCTTCGTGCTGCTGCCAGAGAGAT GAGCTGCCCACCTGGCAGTGGCCGCAGCCTGGCCCTCTGGGCCCAACGCAGGAGGCCCTCAGCACCCGAACACATCTTCCTCCTCCCCACCCGAGCCTGG AGCACTCTAACCCTCGGAGACCCCCTAAGCCCCGTTCCTCCGCAGACCCAGGCCCTCCGGAAGGGGTGAGTGGGGAGGGGCTTTCCTGAGCCTGGAGCTG GGCTTTGGGGCAGCCTGCGACCCTCCCCGCTTGTGTCCCTTCTCCTGTGATCTCTGTGTTTTCCCTTTTCTTTCTGGGGCCAGGAAGTCAGGGTCAACTC CCAGGCCTCAGATGCAGGGGCCCAGAACACCTGCTCTCACCTGAGCCCCAGGTGAAGGGGCCCGGGAACACCTGCTCTCACCTGAGCCCCAGGTGAAGGG GCCCGGGAACACCTGCTCTCACCTGAACCCCAGGTGAAGGGGCCCGGAACACCTGCTCTCACCTGAGCCCCAGGTGAAGGGGCCCGGAACACCTGCTCTC ACCTGAGCCCCAGGTGAAGGGGCCCGGGAACACCTGCTCTCACCTGAGCCCCAGGTGAAGGGGCCCGGGAACACCTGCTCTCACCTGAACCCCAGGTGAA GGGGCCCAGAACACCTGCTCTCACCTGAGCCCCAGGTGAAGGGGCCCGGAACACCTGCTCTCACCTGAGCCCCAGGTGAAGGGGCCCGGGAACACCTGCT CTCACCTGAGCCCCTGGTGAAGGGGCCCGGAACACTTGCTCTCACCTGAGCCCCAGGTGAAGGGGCCCGGAACACCTGCTCTCACCTGAGCCCCCGGTGA AGGGGCCCGGAACACTTGCTCTCACCTGAGCCCCAGGTGAAGGGGCCCGGAACACCTCCTCTCACCTGAGCCCCAGGTGAAGGGGCCCGGAACACCTCCT GTCACCTGAGCCCCAGGTGAAGGGGCCCGGGAACACCTCTCACCTGAACCCGGGGGTCCCATCCCAGGAAGAAGGGCCATCTCAGGACATGAGTCCTCAG GGGCCCTGCACATTCAATCTGAAGGTGACCCTGGCCTGGCTGAAGCTGGAAGAGCTGTGGGGACTCAGCCTGTAAACAGAGCGTAAGGTTCACATGCTGG TTGCTTAATCCGTTTCTGGAGGAAGAGTATGACACCCACTTGTGATGGGGTCCTTGTGCGGTGGGGACCGGGGCCGGCGGGCTCCAGGCCAGCACACCTA ACCCATGGATGTGGAACCTACGGCCGAGAAGGAATGTTGCATGAGTCGGATCCCAGTCCATTGTCAGTGGAGGGTGAGGGTGACCCCATCTGCTATTTTT GTGCTCATCCTCATACAACCATTTGGGGATGTGCCTATTAGGGCTCCGTAAGAACTCAGATGCCTGGGAAGCCCAGCCCCTCAGGTGCCCCCACACACAG CCTTCCCTTGACGCCTACATTTCTAGGCACATGTGAGGCATCTTTCCTGGAGCCCCGAGCCAGCCCTGTCCCTCCCCAGTGCAGCATGGCACTCAGGAGA TACAGGCTGGACATGGGGCAGTCGTTCTGGGGAGGCCTGGCCTAGCAGCCACCCACCTGAGCCCTCCCGGCCAGGCTTCGTGCTGGGGTGGGCCATGTGC CAGGACAGGAGGGTCCCGGCGGAAAGCCAGCCCCGGACTCATCGTGACATTGAGATCCCACTGGAGGGTAGGGGTGGTAATAAACTTCTCCAAACGATCG TTGTCATTTTAGACAG

BOK.F4 (forward primer)
BOK.R6 (reverse primer)
Multiple exon skipping

Frame 0

APSPASRQLGVARCPPRCPGPRRRGRSPPRARE APWTWRSRLGRGRGGRRGGARVLAGLNGRVEVVV GGEQILKPELHPGARAMRRERCGAPHPRRRHGG AAALLGLRRRDHGRL*PLAHRQGAGGPGQGAGP GVRARAAAARRPLLERARACRAGPGTPG*GVRGA AAPGHHVGQGGVPVCGGRGAGRGLCEAGPACHG PRPRGLPGGVRAQDPGNLAAETRRMD*CPQVCG QHRPWPPLPLAGGCTLQLRPLPEGCLLRAAAREM SCPPGSGRSLALWAQRRRPSAPEHIFLLPTRAW STLTLGDPLSPVPPQTQALRKG*VGRGFPEPGA GLWGSLRPSPLVSLLL*SLCFPFSFWGQEVRVNS QASDAGAQNTCSHLSPR*RGPGTPALT*APGEG AREHLLSPEPQVKGPGTPALT*APGEGARNTCS HLSPR*RGPGTPALT*APGEGAREHLLSPEPQVK GPRTPALT*APGEGARNTCSHLSPR*RGPGTPA LT*APGEGARNTCSHLSPR*RGPEHLLSPEPPV KGPGTLALT*APGEGARNTSSHLSPR*RGPEHLL SPEPQVKGPGNTSHLNPGVPSQEEGPSQDMSPQ GPCTFNLKVTLAWLKLEELWGLSL*TERKVHML VA*SVSGGRV*HPLVMGSLCGGDRGRRAPGQHT* PMDVEPTAEKECCMSRIPVHCQWRVRVTPSAIF VLILIQPFGDVPIRAP*ELRCLGSPAPQVPPHT AFP*RLHF*AHVRHLSWSPEPALSLPSAAWHSGD TGWTWGSRSGEAWPSSHPPEPSRPGFVLGWAMC QDRRVPAESQPRTHRDIEIPLEGRGGNKLLQTI VVILD

Frame 1

PQAQPLASWESRAAHLAAQAPDAAAGAPQERGK PRGPGAPGSGVDGAGAGAGRASSRV*MEGSRSS SAASRS*SQNSTPAPAPCGGRGAAPPTRVAAMEV LRRSSVFAAEIMDAFDRSPTDKELVAQAKALGR EYVHARLLRAGLSWSAPERAAPVPGRLAEVCAV LLRLGITWGKVVSLYAVAAGLAVDCVRQAQPAMV HALVDCLGEFVRKTLATWLRRRGGWTDVLKCVV STDPGLRSHWLVAALCSFGRFLKAAFFVLLPER *AAHLAVAAAWPSGPNAGGPQHPNTSSSSPPEPG AL*PSETP*APFLRRPRPSGRGEWGGAFLSLEL GFGAACDPPRLCPFSCDLCVFPFLSGARKSGST PRPQMQGPRTPALT*APGEGAREHLLSPEPQVKG PGNTCSHLNPR*RGPEHLLSPEPQVKGPGTPAL T*APGEGAREHLLSPEPQVKGPGNTCSHLNPR* RGPEHLLSPEPQVKGPGTPALT*APGEGAREHLL SPEPLVKGPGTLALT*APGEGARNTCSHLSPR* RGPEHLLSPEPQVKGPGTPPLT*APGEGARNTS CHLSPR*RGPGTPLT*TRGSHPRKKGHLRT*VLR GPAHSI*R*PWPG*SWKSCGDSACKQSVRFTCW LLNPFLEEEYDTHL*WGPCAVGTGAGGLQASTP NPWMWNLRPRRNVA*VGSQSIVSGG*G*PHLLFL CSSSYNHLGMCLLGLRKNSDAWEAQPLRCPHTQ PSLDAYISRHM*GIFPGAPSQPCPSPVQHGTQE IQAGHGAVVLGRPGLAATHLSPPGQASCWGGPCA RTGGSRRKASPGLIVTLRSHWRVGVVINFSKRS LSF*T

Frame 2

PKPSLSPAGSRALPTSLPRPPTPRQEPPKSAGS PVDLALPARAWTGRAPGRGARPRGSEWKGRGRR RRRADPEARTPPRRPRHAAGEVRRPPPASPPWR CCGAPRSSPPRSWTPLTARPQTRSWWPRPRRWAG STCTRGCCAPASPGARPSVPRRSRDAWLRCARC CCAWASRGARWCPCMRWPRGWPWTV*GRPSLPW STPSWTAWGSSCARPWQPGCGDAADGLMSSSVWS AQTLASAPTGWWLHSAASAAS*RLPSSCCCQRD ELPTWQWPQPGPLGPTQEALSTRTHLPPPHPSL EHSNPRRPPKPRSSADPGPPEGVSGEGLS*AWSW ALGQPATLPACVPSPVISVFSLFFLGPGSQGQL PGLRCRGPEHLLSPEPQVKGPGNTCSHLSPR*R GPGTPALT*TPGEGARNTCSHLSPR*RGPEHLLS PEPQVKGPGNTCSHLSPR*RGPGTPALT*TPGE GAQNTCSHLSPR*RGPEHLLSPEPQVKGPGNTC SHLSPW*RGPEHLLSPEPQVKGPGTPALT*APGE GARNTCSHLSPR*RGPEHLLSPEPQVKGPGTPP VT*APGEGAREHLSPEPGGPIPGRRAISGHESS GALHIQSEGDPGLAEAGRAVGTQPVNRA*GSHAG CLIRFWRKSMTPTCDGVLVRWGPGPAGSRPAHL THGCGTYGREGMLHESDPSPLSVEGEGDPICYF CAHPHTTIWGCAY*GSVRTQMPGKPSPSGAPTHS LPLTPTFLGTCEASFLEPRASPVPPQCSMALRR YRLDMGQSFWGGLA*QPPT*ALPARLRAGVGHV PGQEGPGGKPAPDSS*H*DPTGG*GW**TSPNDR CHFRQ

Sequence BOK.cAug05

GCCCCAAGCCCAGCCTCTCGCCAGCTGGGAGTCGCGCGCTGCCCACCTCGCTGCCCAGGCCCCCGACGCCGCGGCAGGAGCCCCCCAAGAGCGCGGGAAG CCCCGTGGACCTGGCGCTCCCGGCTCGGGCGTGGACGGGGCGGGCGCCGGGGCGGGGCGCGCGTCCTCGCGGGTCTGAATGGAAGGGTCGAGGTCGTCGT CGGCGGCGAGCAGATCCTGAAGCCAGAACTCCACCCCGGCGCCCGCGCCATGCGGCGGGAGAGGTGCGGCGCCCCCCACCCGCGTCGCCGCCATGGAGGT GCTGCGGCGCTCCTCGGTCTTCGCCGCCGAGATCATGGACGCCTTTGACCGCTCGCCCACAGACAAGGAGCTGGTGGCCCAGGCCAAGGCGCTGGGCCGG GAGTACGTGCACGCGCGGCTGCTGCGCGCCGGCCTCTCCTGGAGCGCGCCCGAGCGTGCCGCGCCGGTCCCGGGACGCCTGGCTGAGGTGTGCGCGGTGC TGCTGCGCCTGGATTCTTGCTGTTACTGGCCGAGATCCCGCCCGCTGCCCTCTGGATTCCGAGGCCTCCGAGGCCCCCCCATTGGAAACTGCGCCCACCG GGCTGGGTAGCCAAAACCTCAGTATTCGTTGGTGCTGTGAGGACATCTGGGGGTGCTCGGTTCTGGGGTCACACACGGTCCACTGGCTGCCCCCACCGTC TCCAAGGCGATGAGCTGGAGATGATCCGGCCCAGCGTCTACCGCAACGTGGCGCGTCAGCTGCACATCTCCCTGCAGTCTGAGCCTGTGGTGACCGATGC GTTCCTGGCCGTGGCTGGCCACATCTTCTCTGCAGGCATCACGTGGGGCAAGGTGGTGTCCCTGTATGCGGTGGCCGCGGGGCTGGCCGTGGACTGTGTG AGGCAGGCCCAGCCTGCCATGGTCCACGCCCTCGTGGACTGCCTGGGGGAGTTCGTGCGCAAGACCCTGGCAACCTGGCTGCGGAGACGCGGCGGATGGA CTGATGTCCTCAAGTGTGTGGTCAGCACAGACCCTGGCCTCCGCTCCCACTGGCTGGTGGCTGCACTCTGCAGCTTCGGCCGCTTCCTGAAGGCTGCCTT CTTCGTGCTGCTGCCAGAGAGATGAGCTGCCCACCTGGCAGTGGCCGCAGCCTGGCCCTCTGGGCCCAACGCAGGAGGCCCTCAGCACCCGAACACATCT TCCTCCTCCCCACCCGAGCCTGGAGCACTCTAACCCTCGGAGACCCCCTAAGCCCCGTTCCTCCGCAGACCCAGGCCCTCCGGAAGGGGTGAGTGGGGAG GGGCTTTCCTGAGCCTGGAGCTGGGCTTTGGGGCAGCCTGCGACCCTCCCCGCTTGTGTCCCTTCTCCTGTGATCTCTGTGTTTTCCCTTTTCTTTCTGG GGCCAGGAAGTCAGGGTCAACTCCCAGGCCTCAGATGCAGGGGCCCAGAACACCTGCTCTCACCTGAGCCCCAGGTGAAGGGGCCCGGGAACACCTGCTC TCACCTGAGCCCCAGGTGAAGGGGCCCGGGAACACCTGCTCTCACCTGAACCCCAGGTGAAGGGGCCCGGAACACCTGCTCTCACCTGAGCCCCAGGTGA AGGGGCCCGGAACACCTGCTCTCACCTGAGCCCCAGGTGAAGGGGCCCGGGAACACCTGCTCTCACCTGAGCCCCAGGTGAAGGGGCCCGGGAACACCTG CTCTCACCTGAACCCCAGGTGAAGGGGCCCAGAACACCTGCTCTCACCTGAGCCCCAGGTGAAGGGGCCCGGAACACCTGCTCTCACCTGAGCCCCAGGT GAAGGGGCCCGGGAACACCTGCTCTCACCTGAGCCCCTGGTGAAGGGGCCCGGAACACTTGCTCTCACCTGAGCCCCAGGTGAAGGGGCCCGGAACACCT GCTCTCACCTGAGCCCCCGGTGAAGGGGCCCGGAACACTTGCTCTCACCTGAGCCCCAGGTGAAGGGGCCCGGAACACCTCCTCTCACCTGAGCCCCAGG TGAAGGGGCCCGGAACACCTCCTGTCACCTGAGCCCCAGGTGAAGGGGCCCGGGAACACCTCTCACCTGAACCCGGGGGTCCCATCCCAGGAAGAAGGGC CATCTCAGGACATGAGTCCTCAGGGGCCCTGCACATTCAATCTGAAGGTGACCCTGGCCTGGCTGAAGCTGGAAGAGCTGTGGGGACTCAGCCTGTAAAC AGAGCGTAAGGTTCACATGCTGGTTGCTTAATCCGTTTCTGGAGGAAGAGTATGACACCCACTTGTGATGGGGTCCTTGTGCGGTGGGGACCGGGGCCGG CGGGCTCCAGGCCAGCACACCTAACCCATGGATGTGGAACCTACGGCCGAGAAGGAATGTTGCATGAGTCGGATCCCAGTCCATTGTCAGTGGAGGGTGA GGGTGACCCCATCTGCTATTTTTGTGCTCATCCTCATACAACCATTTGGGGATGTGCCTATTAGGGCTCCGTAAGAACTCAGATGCCTGGGAAGCCCAGC CCCTCAGGTGCCCCCACACACAGCCTTCCCTTGACGCCTACATTTCTAGGCACATGTGAGGCATCTTTCCTGGAGCCCCGAGCCAGCCCTGTCCCTCCCC AGTGCAGCATGGCACTCAGGAGATACAGGCTGGACATGGGGCAGTCGTTCTGGGGAGGCCTGGCCTAGCAGCCACCCACCTGAGCCCTCCCGGCCAGGCT TCGTGCTGGGGTGGGCCATGTGCCAGGACAGGAGGGTCCCGGCGGAAAGCCAGCCCCGGACTCATCGTGACATTGAGATCCCACTGGAGGGTAGGGGTGG TAATAAACTTCTCCAAACGATCGTTGTCATTTTAGACAG

BOK.F4 (forward primer)
BOK.R6 (reverse primer)
Multiple exon skipping

Frame 0

APSPASRQLGVARCPPRCPGPRRRGRSPPRARE APWTWRSRLGRGRGGRRGGARVLAGLNGRVEVVV GGEQILKPELHPGARAMRRERCGAPHPRRRHGG AAALLGLRRRDHGRL*PLAHRQGAGGPGQGAGP GVRARAAAARRPLLERARACRAGPGTPG*GVRGA AAPGFLLLLAEIPPAALWIPRPPRPPHWKLRPP GWVAKTSVFVGAVRTSGGARFWGHTRSTGCPHR LQGDELEMIRPSVYRNVARQLHISLQSEPVVTDA FLAVAGHIFSAGITWGKVVSLYAVAAGLAVDCV RQAQPAMVHALVDCLGEFVRKTLATWLRRRGGW TDVLKCVVSTDPGLRSHWLVAALCSFGRFLKAAF FVLLPER*AAHLAVAAAWPSGPNAGGPQHPNTS SSSPPEPGAL*PSETP*APFLRRPRPSGRGEWG GAFLSLELGFGAACDPPRLCPFSCDLCVFPFLSG ARKSGSTPRPQMQGPRTPALT*APGEGAREHLL SPEPQVKGPGNTCSHLNPR*RGPEHLLSPEPQV KGPGTPALT*APGEGAREHLLSPEPQVKGPGNTC SHLNPR*RGPEHLLSPEPQVKGPGTPALT*APG EGAREHLLSPEPLVKGPGTLALT*APGEGARNT CSHLSPR*RGPEHLLSPEPQVKGPGTPPLT*APG EGARNTSCHLSPR*RGPGTPLT*TRGSHPRKKG HLRT*VLRGPAHSI*R*PWPG*SWKSCGDSACK QSVRFTCWLLNPFLEEEYDTHL*WGPCAVGTGAG GLQASTPNPWMWNLRPRRNVA*VGSQSIVSGG* G*PHLLFLCSSSYNHLGMCLLGLRKNSDAWEAQ PLRCPHTQPSLDAYISRHM*GIFPGAPSQPCPSP VQHGTQEIQAGHGAVVLGRPGLAATHLSPPGQA SCWGGPCARTGGSRRKASPGLIVTLRSHWRVGV VINFSKRSLSF*T

Frame 1

PQAQPLASWESRAAHLAAQAPDAAAGAPQERGK PRGPGAPGSGVDGAGAGAGRASSRV*MEGSRSS SAASRS*SQNSTPAPAPCGGRGAAPPTRVAAMEV LRRSSVFAAEIMDAFDRSPTDKELVAQAKALGR EYVHARLLRAGLSWSAPERAAPVPGRLAEVCAV LLRLDSCCYWPRSRPLPSGFRGLRGPPIGNCAHR AG*PKPQYSLVL*GHLGVLGSGVTHGPLAAPTV SKAMSWR*SGPASTATWRVSCTSPCSLSLW*PM RSWPWLATSSLQASRGARWCPCMRWPRGWPWTV* GRPSLPWSTPSWTAWGSSCARPWQPGCGDAADG LMSSSVWSAQTLASAPTGWWLHSAASAAS*RLP SSCCCQRDELPTWQWPQPGPLGPTQEALSTRTHL PPPHPSLEHSNPRRPPKPRSSADPGPPEGVSGE GLS*AWSWALGQPATLPACVPSPVISVFSLFFL GPGSQGQLPGLRCRGPEHLLSPEPQVKGPGNTCS HLSPR*RGPGTPALT*TPGEGARNTCSHLSPR* RGPEHLLSPEPQVKGPGNTCSHLSPR*RGPGTP ALT*TPGEGAQNTCSHLSPR*RGPEHLLSPEPQV KGPGNTCSHLSPW*RGPEHLLSPEPQVKGPGTP ALT*APGEGARNTCSHLSPR*RGPEHLLSPEPQ VKGPGTPPVT*APGEGAREHLSPEPGGPIPGRRA ISGHESSGALHIQSEGDPGLAEAGRAVGTQPVN RA*GSHAGCLIRFWRKSMTPTCDGVLVRWGPGP AGSRPAHLTHGCGTYGREGMLHESDPSPLSVEGE GDPICYFCAHPHTTIWGCAY*GSVRTQMPGKPS PSGAPTHSLPLTPTFLGTCEASFLEPRASPVPP QCSMALRRYRLDMGQSFWGGLA*QPPT*ALPARL RAGVGHVPGQEGPGGKPAPDSS*H*DPTGG*GW **TSPNDRCHFRQ

Frame 2

PKPSLSPAGSRALPTSLPRPPTPRQEPPKSAGS PVDLALPARAWTGRAPGRGARPRGSEWKGRGRR RRRADPEARTPPRRPRHAAGEVRRPPPASPPWR CCGAPRSSPPRSWTPLTARPQTRSWWPRPRRWAG STCTRGCCAPASPGARPSVPRRSRDAWLRCARC CCAWILAVTGRDPARCPLDSEASEAPPLETAPT GLGSQNLSIRWCCEDIWGCSVLGSHTVHWLPPPS PRR*AGDDPAQRLPQRGASAAHLPAV*ACGDRC VPGRGWPHLLCRHHVGQGGVPVCGGRGAGRGLC EAGPACHGPRPRGLPGGVRAQDPGNLAAETRRMD *CPQVCGQHRPWPPLPLAGGCTLQLRPLPEGCL LRAAAREMSCPPGSGRSLALWAQRRRPSAPEHI FLLPTRAWSTLTLGDPLSPVPPQTQALRKG*VGR GFPEPGAGLWGSLRPSPLVSLLL*SLCFPFSFW GQEVRVNSQASDAGAQNTCSHLSPR*RGPGTPA LT*APGEGAREHLLSPEPQVKGPGTPALT*APGE GARNTCSHLSPR*RGPGTPALT*APGEGAREHL LSPEPQVKGPRTPALT*APGEGARNTCSHLSPR *RGPGTPALT*APGEGARNTCSHLSPR*RGPEHL LSPEPPVKGPGTLALT*APGEGARNTSSHLSPR *RGPEHLLSPEPQVKGPGNTSHLNPGVPSQEEG PSQDMSPQGPCTFNLKVTLAWLKLEELWGLSL*T ERKVHMLVA*SVSGGRV*HPLVMGSLCGGDRGR RAPGQHT*PMDVEPTAEKECCMSRIPVHCQWRV RVTPSAIFVLILIQPFGDVPIRAP*ELRCLGSPA PQVPPHTAFP*RLHF*AHVRHLSWSPEPALSLP SAAWHSGDTGWTWGSRSGEAWPSSHPPEPSRPG FVLGWAMCQDRRVPAESQPRTHRDIEIPLEGRGG NKLLQTIVVILD