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Sequences

Sequence BOK.fAug05

GCCCCAAGCCCAGCCTCTCGCCAGCTGGGAGTCGCGCGCTGCCCACCTCGCTGCCCAGGCCCCCGACGCCGCGGCAGGAGCCCCCCAAGAGCGCGGGAAG CCCCGTGGACCTGGCGCTCCCGGCTCGGGCGTGGACGGGGCGGGCGCCGGGGCGGGGCGCGCGTCCTCGCGGGTCTGAATGGAAGGGTCGAGGTCGTCGT CGGCGGCGAGCAGATCCTGAAGCCAGAACTCCACCCCGGCGCCCGCGCCATGCGGCGGGAGAGGCATCACGTGGGGCAAGGTGGTGTCCCTGTATGCGGT GGCCGCGGGGCTGGCCGTGGACTGTGTGAGGCAGGCCCAGCCTGCCATGGTCCACGCCCTCGTGGACTGCCTGGGGGAGTTCGTGCGCAAGACCCTGGCA ACCTGGCTGCGGAGACGCGGCGGATGGACTGATGTCCTCAAGTGTGTGGTCAGCACAGACCCTGGCCTCCGCTCCCACTGGCTGGTGGCTGCACTCTGCA GCTTCGGCCGCTTCCTGAAGGCTGCCTTCTTCGTGCTGCTGCCAGAGAGATGAGCTGCCCACCTGGCAGTGGCCGCAGCCTGGCCCTCTGGGCCCAACGC AGGAGGCCCTCAGCACCCGAACACATCTTCCTCCTCCCCACCCGAGCCTGGAGCACTCTAACCCTCGGAGACCCCCTAAGCCCCGTTCCTCCGCAGACCC AGGCCCTCCGGAAGGGGTGAGTGGGGAGGGGCTTTCCTGAGCCTGGAGCTGGGCTTTGGGGCAGCCTGCGACCCTCCCCGCTTGTGTCCCTTCTCCTGTG ATCTCTGTGTTTTCCCTTTTCTTTCTGGGGCCAGGAAGTCAGGGTCAACTCCCAGGCCTCAGATGCAGGGGCCCAGAACACCTGCTCTCACCTGAGCCCC AGGTGAAGGGGCCCGGGAACACCTGCTCTCACCTGAGCCCCAGGTGAAGGGGCCCGGGAACACCTGCTCTCACCTGAACCCCAGGTGAAGGGGCCCGGAA CACCTGCTCTCACCTGAGCCCCAGGTGAAGGGGCCCGGAACACCTGCTCTCACCTGAGCCCCAGGTGAAGGGGCCCGGGAACACCTGCTCTCACCTGAGC CCCAGGTGAAGGGGCCCAGAACACCTGCTCTCACCTGAGCCCCAGGTGAAGGGGCCCGGAACACCTGCTCTCACCTGAGCCCCAGGTGAAGGGGCCCGGG AACACCTGCTCTCACCTGAGCCCCTGGTGAAGGGGCCCGGAACACTTGCTCTCACCTGAGCCCCAGGTGAAGGGGCCCGGAACACCTGCTCTCACCTGAG CCCCCGGTGAAGGGGCCCGGAACACTTGCTCTCACCTGAGCCCCAGGTGAAGGGGCCCGGAACACCTCCTCTCACCTGAGCCCCAGGTGAAGGGGCCCGG AACACCTCCTGTCACCTGAGCCCCAGGTGAAGGGGCCCGGGAACACCTCTCACCTGAACCCGGGGGTCCCATCCCAGGAAGAAGGGCCATCTCAGGACAT GAGTCCTCAGGGGCCCTGCACATTCAATCTGAAGGTGACCCTGGCCTGGCTGAAGCTGGAAGAGCTGTGGGGACTCAGCCTGTAAACAGAGCGTAAGGTT CACATGCTGGTTGCTTAATCCGTTTCTGGAGGAAGAGTATGACACCCACTTGTGATGGGGTCCTTGTGCGGTGGGGACCGGGGCCGGCGGGCTCCAGGCC AGCACACCTAACCCATGGATGTGGAACCTACGGCCGAGAAGGAATGTTGCATGAGTCGGATCCCAGTCCATTGTCAGTGGAGGGTGAGGGTGACCCCATC TGCTATTTTTGTGCTCATCCTCATACAACCATTTGGGGATGTGCCTATTAGGGCTCCGTAAGAACTCAGATGCCTGGGAAGCCCAGCCCCTCAGGTGCCC CCACACACAGCCTTCCCTTGACGCCTACATTTCTAGGCACATGTGAGGCATCTTTCCTGGAGCCCCGAGCCAGCCCTGTCCCTCCCCAGTGCAGCATGGC ACTCAGGAGATACAGGCTGGACATGGGGCAGTCGTTCTGGGGAGGCCTGGCCTAGCAGCCACCCACCTGAGCCCTCCCGGCCAGGCTTCGTGCTGGGGTG GGCCATGTGCCAGGACAGGAGGGTCCCGGCGGAAAGCCAGCCCCGGACTCATCGTGACATTGAGATCCCACTGGAGGGTAGGGGTGGTAATAAACTTCTC CAAACGATCGTTGTCATTTTAGACAGAA

BOK.F4 (forward primer)
BOK.R6 (reverse primer)
Single exon skipping

Frame 0

APSPASRQLGVARCPPRCPGPRRRGRSPPRARE APWTWRSRLGRGRGGRRGGARVLAGLNGRVEVVV GGEQILKPELHPGARAMRRERHHVGQGGVPVCG GRGAGRGLCEAGPACHGPRPRGLPGGVRAQDPG NLAAETRRMD*CPQVCGQHRPWPPLPLAGGCTLQ LRPLPEGCLLRAAAREMSCPPGSGRSLALWAQR RRPSAPEHIFLLPTRAWSTLTLGDPLSPVPPQT QALRKG*VGRGFPEPGAGLWGSLRPSPLVSLLL* SLCFPFSFWGQEVRVNSQASDAGAQNTCSHLSP R*RGPGTPALT*APGEGAREHLLSPEPQVKGPG TPALT*APGEGARNTCSHLSPR*RGPGTPALT*A PGEGAQNTCSHLSPR*RGPEHLLSPEPQVKGPG NTCSHLSPW*RGPEHLLSPEPQVKGPGTPALT* APGEGARNTCSHLSPR*RGPEHLLSPEPQVKGPG TPPVT*APGEGAREHLSPEPGGPIPGRRAISGH ESSGALHIQSEGDPGLAEAGRAVGTQPVNRA*G SHAGCLIRFWRKSMTPTCDGVLVRWGPGPAGSRP AHLTHGCGTYGREGMLHESDPSPLSVEGEGDPI CYFCAHPHTTIWGCAY*GSVRTQMPGKPSPSGA PTHSLPLTPTFLGTCEASFLEPRASPVPPQCSMA LRRYRLDMGQSFWGGLA*QPPT*ALPARLRAGV GHVPGQEGPGGKPAPDSS*H*DPTGG*GW**TS PNDRCHFRQ

Frame 1

PQAQPLASWESRAAHLAAQAPDAAAGAPQERGK PRGPGAPGSGVDGAGAGAGRASSRV*MEGSRSS SAASRS*SQNSTPAPAPCGGRGITWGKVVSLYAV AAGLAVDCVRQAQPAMVHALVDCLGEFVRKTLA TWLRRRGGWTDVLKCVVSTDPGLRSHWLVAALC SFGRFLKAAFFVLLPER*AAHLAVAAAWPSGPNA GGPQHPNTSSSSPPEPGAL*PSETP*APFLRRP RPSGRGEWGGAFLSLELGFGAACDPPRLCPFSC DLCVFPFLSGARKSGSTPRPQMQGPRTPALT*AP GEGAREHLLSPEPQVKGPGNTCSHLNPR*RGPE HLLSPEPQVKGPGTPALT*APGEGAREHLLSPE PQVKGPRTPALT*APGEGARNTCSHLSPR*RGPG TPALT*APGEGARNTCSHLSPR*RGPEHLLSPE PPVKGPGTLALT*APGEGARNTSSHLSPR*RGP EHLLSPEPQVKGPGNTSHLNPGVPSQEEGPSQDM SPQGPCTFNLKVTLAWLKLEELWGLSL*TERKV HMLVA*SVSGGRV*HPLVMGSLCGGDRGRRAPG QHT*PMDVEPTAEKECCMSRIPVHCQWRVRVTPS AIFVLILIQPFGDVPIRAP*ELRCLGSPAPQVP PHTAFP*RLHF*AHVRHLSWSPEPALSLPSAAW HSGDTGWTWGSRSGEAWPSSHPPEPSRPGFVLGW AMCQDRRVPAESQPRTHRDIEIPLEGRGGNKLL QTIVVILDR

Frame 2

PKPSLSPAGSRALPTSLPRPPTPRQEPPKSAGS PVDLALPARAWTGRAPGRGARPRGSEWKGRGRR RRRADPEARTPPRRPRHAAGEASRGARWCPCMR WPRGWPWTV*GRPSLPWSTPSWTAWGSSCARPWQ PGCGDAADGLMSSSVWSAQTLASAPTGWWLHSA ASAAS*RLPSSCCCQRDELPTWQWPQPGPLGPT QEALSTRTHLPPPHPSLEHSNPRRPPKPRSSADP GPPEGVSGEGLS*AWSWALGQPATLPACVPSPV ISVFSLFFLGPGSQGQLPGLRCRGPEHLLSPEP QVKGPGNTCSHLSPR*RGPGTPALT*TPGEGARN TCSHLSPR*RGPEHLLSPEPQVKGPGNTCSHLS PR*RGPEHLLSPEPQVKGPGTPALT*APGEGAR EHLLSPEPLVKGPGTLALT*APGEGARNTCSHLS PR*RGPEHLLSPEPQVKGPGTPPLT*APGEGAR NTSCHLSPR*RGPGTPLT*TRGSHPRKKGHLRT *VLRGPAHSI*R*PWPG*SWKSCGDSACKQSVRF TCWLLNPFLEEEYDTHL*WGPCAVGTGAGGLQA STPNPWMWNLRPRRNVA*VGSQSIVSGG*G*PH LLFLCSSSYNHLGMCLLGLRKNSDAWEAQPLRCP HTQPSLDAYISRHM*GIFPGAPSQPCPSPVQHG TQEIQAGHGAVVLGRPGLAATHLSPPGQASCWG GPCARTGGSRRKASPGLIVTLRSHWRVGVVINFS KRSLSF*TE

Sequence BOK.dAug05

GCCCCAAGCCCAGCCTCTCGCCAGCTGGGAGTCGCGCGCTGCCCACCTCGCTGCCCAGGCCCCCGACGCCGCGGCAGGAGCCCCCCAAGAGCGCGGGAAG CCCCGTGGACCTGGCGCTCCCGGCTCGGGCGTGGACGGGGCGGGCGCCGGGGCGGGGCGCGCGTCCTCGCGGGTCTGAATGGAAGGGTCGAGGTCGTCGT CGGCGGCGAGCAGATCCTGAAGCCAGAACTCCACCCCGGCGCCCGCGCCATGCGGCGGGAGAGGTGCGGCGCCCCCCACCCGCGTCGCCGCCATGGAGGT GCTGCGGCGCTCCTCGGTCTTCGCCGCCGAGATCATGGACGCCTTTGACCGCTCGCCCACAGACAAGGAGCTGGTGGCCCAGGCCAAGGCGCTGGGCCGG GAGTACGTGCACGCGCGGCTGCTGCGCGCCGGCCTCTCCTGGAGCGCGCCCGAGCGTGCCGCGCCGGTCCCGGGACGCCTGGCTGAGGTGTGCGCGGTGC TGCTGCGCCTGGGCATCACGTGGGGCAAGGTGGTGTCCCTGTATGCGGTGGCCGCGGGGCTGGCCGTGGACTGTGTGAGGCAGGCCCAGCCTGCCATGGT CCACGCCCTCGTGGACTGCCTGGGGGAGTTCGTGCGCAAGACCCTGGCAACCTGGCTGCGGAGACGCGGCGGATGGACTGATGTCCTCAAGTGTGTGGTC AGCACAGACCCTGGCCTCCGCTCCCACTGGCTGGTGGCTGCACTCTGCAGCTTCGGCCGCTTCCTGAAGGCTGCCTTCTTCGTGCTGCTGCCAGAGAGAT GAGCTGCCCACCTGGCAGTGGCCGCAGCCTGGCCCTCTGGGCCCAACGCAGGAGGCCCTCAGCACCCGAACACATCTTCCTCCTCCCCACCCGAGCCTGG AGCACTCTAACCCTCGGAGACCCCCTAAGCCCCGTTCCTCCGCAGACCCAGGCCCTCCGGAAGGGGTGAGTGGGGAGGGGCTTTCCTGAGCCTGGAGCTG GGCTTTGGGGCAGCCTGCGACCCTCCCCGCTTGTGTCCCTTCTCCTGTGATCTCTGTGTTTTCCCTTTTCTTTCTGGGGCCAGGAAGTCAGGGTCAACTC CCAGGCCTCAGATGCAGGGGCCCAGAACACCTGCTCTCACCTGAGCCCCAGGTGAAGGGGCCCGGGAACACCTGCTCTCACCTGAGCCCCAGGTGAAGGG GCCCGGGAACACCTGCTCTCACCTGAACCCCAGGTGAAGGGGCCCGGAACACCTGCTCTCACCTGAGCCCCAGGTGAAGGGGCCCGGAACACCTGCTCTC ACCTGAGCCCCAGGTGAAGGGGCCCGGGAACACCTGCTCTCACCTGAGCCCCAGGTGAAGGGGCCCGGGAACACCTGCTCTCACCTGAACCCCAGGTGAA GGGGCCCAGAACACCTGCTCTCACCTGAGCCCCAGGTGAAGGGGCCCGGAACACCTGCTCTCACCTGAGCCCCAGGTGAAGGGGCCCGGGAACACCTGCT CTCACCTGAGCCCCTGGTGAAGGGGCCCGGAACACTTGCTCTCACCTGAGCCCCAGGTGAAGGGGCCCGGAACACCTGCTCTCACCTGAGCCCCCGGTGA AGGGGCCCGGAACACTTGCTCTCACCTGAGCCCCAGGTGAAGGGGCCCGGAACACCTCCTCTCACCTGAGCCCCAGGTGAAGGGGCCCGGAACACCTCCT GTCACCTGAGCCCCAGGTGAAGGGGCCCGGGAACACCTCTCACCTGAACCCGGGGGTCCCATCCCAGGAAGAAGGGCCATCTCAGGACATGAGTCCTCAG GGGCCCTGCACATTCAATCTGAAGGTGACCCTGGCCTGGCTGAAGCTGGAAGAGCTGTGGGGACTCAGCCTGTAAACAGAGCGTAAGGTTCACATGCTGG TTGCTTAATCCGTTTCTGGAGGAAGAGTATGACACCCACTTGTGATGGGGTCCTTGTGCGGTGGGGACCGGGGCCGGCGGGCTCCAGGCCAGCACACCTA ACCCATGGATGTGGAACCTACGGCCGAGAAGGAATGTTGCATGAGTCGGATCCCAGTCCATTGTCAGTGGAGGGTGAGGGTGACCCCATCTGCTATTTTT GTGCTCATCCTCATACAACCATTTGGGGATGTGCCTATTAGGGCTCCGTAAGAACTCAGATGCCTGGGAAGCCCAGCCCCTCAGGTGCCCCCACACACAG CCTTCCCTTGACGCCTACATTTCTAGGCACATGTGAGGCATCTTTCCTGGAGCCCCGAGCCAGCCCTGTCCCTCCCCAGTGCAGCATGGCACTCAGGAGA TACAGGCTGGACATGGGGCAGTCGTTCTGGGGAGGCCTGGCCTAGCAGCCACCCACCTGAGCCCTCCCGGCCAGGCTTCGTGCTGGGGTGGGCCATGTGC CAGGACAGGAGGGTCCCGGCGGAAAGCCAGCCCCGGACTCATCGTGACATTGAGATCCCACTGGAGGGTAGGGGTGGTAATAAACTTCTCCAAACGATCG TTGTCATTTTAGACAG

BOK.F4 (forward primer)
BOK.R6 (reverse primer)
Single exon skipping

Frame 0

APSPASRQLGVARCPPRCPGPRRRGRSPPRARE APWTWRSRLGRGRGGRRGGARVLAGLNGRVEVVV GGEQILKPELHPGARAMRRERCGAPHPRRRHGG AAALLGLRRRDHGRL*PLAHRQGAGGPGQGAGP GVRARAAAARRPLLERARACRAGPGTPG*GVRGA AAPGHHVGQGGVPVCGGRGAGRGLCEAGPACHG PRPRGLPGGVRAQDPGNLAAETRRMD*CPQVCG QHRPWPPLPLAGGCTLQLRPLPEGCLLRAAAREM SCPPGSGRSLALWAQRRRPSAPEHIFLLPTRAW STLTLGDPLSPVPPQTQALRKG*VGRGFPEPGA GLWGSLRPSPLVSLLL*SLCFPFSFWGQEVRVNS QASDAGAQNTCSHLSPR*RGPGTPALT*APGEG AREHLLSPEPQVKGPGTPALT*APGEGARNTCS HLSPR*RGPGTPALT*APGEGAREHLLSPEPQVK GPRTPALT*APGEGARNTCSHLSPR*RGPGTPA LT*APGEGARNTCSHLSPR*RGPEHLLSPEPPV KGPGTLALT*APGEGARNTSSHLSPR*RGPEHLL SPEPQVKGPGNTSHLNPGVPSQEEGPSQDMSPQ GPCTFNLKVTLAWLKLEELWGLSL*TERKVHML VA*SVSGGRV*HPLVMGSLCGGDRGRRAPGQHT* PMDVEPTAEKECCMSRIPVHCQWRVRVTPSAIF VLILIQPFGDVPIRAP*ELRCLGSPAPQVPPHT AFP*RLHF*AHVRHLSWSPEPALSLPSAAWHSGD TGWTWGSRSGEAWPSSHPPEPSRPGFVLGWAMC QDRRVPAESQPRTHRDIEIPLEGRGGNKLLQTI VVILD

Frame 1

PQAQPLASWESRAAHLAAQAPDAAAGAPQERGK PRGPGAPGSGVDGAGAGAGRASSRV*MEGSRSS SAASRS*SQNSTPAPAPCGGRGAAPPTRVAAMEV LRRSSVFAAEIMDAFDRSPTDKELVAQAKALGR EYVHARLLRAGLSWSAPERAAPVPGRLAEVCAV LLRLGITWGKVVSLYAVAAGLAVDCVRQAQPAMV HALVDCLGEFVRKTLATWLRRRGGWTDVLKCVV STDPGLRSHWLVAALCSFGRFLKAAFFVLLPER *AAHLAVAAAWPSGPNAGGPQHPNTSSSSPPEPG AL*PSETP*APFLRRPRPSGRGEWGGAFLSLEL GFGAACDPPRLCPFSCDLCVFPFLSGARKSGST PRPQMQGPRTPALT*APGEGAREHLLSPEPQVKG PGNTCSHLNPR*RGPEHLLSPEPQVKGPGTPAL T*APGEGAREHLLSPEPQVKGPGNTCSHLNPR* RGPEHLLSPEPQVKGPGTPALT*APGEGAREHLL SPEPLVKGPGTLALT*APGEGARNTCSHLSPR* RGPEHLLSPEPQVKGPGTPPLT*APGEGARNTS CHLSPR*RGPGTPLT*TRGSHPRKKGHLRT*VLR GPAHSI*R*PWPG*SWKSCGDSACKQSVRFTCW LLNPFLEEEYDTHL*WGPCAVGTGAGGLQASTP NPWMWNLRPRRNVA*VGSQSIVSGG*G*PHLLFL CSSSYNHLGMCLLGLRKNSDAWEAQPLRCPHTQ PSLDAYISRHM*GIFPGAPSQPCPSPVQHGTQE IQAGHGAVVLGRPGLAATHLSPPGQASCWGGPCA RTGGSRRKASPGLIVTLRSHWRVGVVINFSKRS LSF*T

Frame 2

PKPSLSPAGSRALPTSLPRPPTPRQEPPKSAGS PVDLALPARAWTGRAPGRGARPRGSEWKGRGRR RRRADPEARTPPRRPRHAAGEVRRPPPASPPWR CCGAPRSSPPRSWTPLTARPQTRSWWPRPRRWAG STCTRGCCAPASPGARPSVPRRSRDAWLRCARC CCAWASRGARWCPCMRWPRGWPWTV*GRPSLPW STPSWTAWGSSCARPWQPGCGDAADGLMSSSVWS AQTLASAPTGWWLHSAASAAS*RLPSSCCCQRD ELPTWQWPQPGPLGPTQEALSTRTHLPPPHPSL EHSNPRRPPKPRSSADPGPPEGVSGEGLS*AWSW ALGQPATLPACVPSPVISVFSLFFLGPGSQGQL PGLRCRGPEHLLSPEPQVKGPGNTCSHLSPR*R GPGTPALT*TPGEGARNTCSHLSPR*RGPEHLLS PEPQVKGPGNTCSHLSPR*RGPGTPALT*TPGE GAQNTCSHLSPR*RGPEHLLSPEPQVKGPGNTC SHLSPW*RGPEHLLSPEPQVKGPGTPALT*APGE GARNTCSHLSPR*RGPEHLLSPEPQVKGPGTPP VT*APGEGAREHLSPEPGGPIPGRRAISGHESS GALHIQSEGDPGLAEAGRAVGTQPVNRA*GSHAG CLIRFWRKSMTPTCDGVLVRWGPGPAGSRPAHL THGCGTYGREGMLHESDPSPLSVEGEGDPICYF CAHPHTTIWGCAY*GSVRTQMPGKPSPSGAPTHS LPLTPTFLGTCEASFLEPRASPVPPQCSMALRR YRLDMGQSFWGGLA*QPPT*ALPARLRAGVGHV PGQEGPGGKPAPDSS*H*DPTGG*GW**TSPNDR CHFRQ