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Sequence PIK3R3.fAug05
TTCTGATTGAGGCTGGGGGAGAGCGCGGATGGCTGATTGGGGAGCCGAAGCCTAGAGAGCGGTGGGGAGACGTGAAAGTCGAGATGGAGAGCAGCTTTTTGAACATGTTCTCAGGCACTTGACAGAATCCCGCTCTTCCACCAAAGCCACCTAAGCCAATGACTTCAGCAGTTCCAAATGGAATGAAGGACAGTTCTGTT
TCTCTTCAGGATGCAGAATGGTACTGGGGGGATATTTCAAGGGAGGAGGTAAATGACAAATTGCGGGATATGCCAGATGGGACCTTCTTGGTCCGAGATG
CCTCAACAAAAATGCAGGGAGATTATACTTTGACTTTGCGGAAGGGAGGCAATAATAAGTTAATAAAGATCTATCACCGGGATGGTAAATATGGCTTTTC
TGATCCTCTGACATTTAATTCCGTGGTGGAGCTCATTAACCACTATCACCATGAATCTCTTGCTCAGTACAATCCCAAACTTGATGTGAAGCTGATGTAC
CCAGTGTCCAGATACCAACAGGATCAGTTGGTAAAAGAAGATAATATTGATGCAGTAGGTAAAAAACTGCAAGAATACCACTCTCAGTATCAGGAGAAGA
GTAAAGAGTATGATAGGCTGTATGAAGAATATACTAGAACATCCCAGGAAATACAGATGAAGAGGACTGCAATAGAAGCTTTTAATGAAACAATTAAAAT
ATTTGAAGAGCAGTGTCACACACAAGAACAACATAGCAAAGAATATATTGAGCGATTTCGCAGAGAGGG
- PIK3R3.F1 (forward primer)
- PIK3R3.R1 (reverse primer)
- Single exon skipping
Frame 0
F*LRLGESADG*LGSRSLESGGET*KSRWRAAF*TCSQALDRIPLFHQSHLSQ*LQQFQME*RTVLF
LFRMQNGTGGIFQGRR*MTNCGICQMGPSWSEM
PQQKCREIIL*LCGREAIIS**RSITGMVNMAF
LIL*HLIPWWSSLTTITMNLLLSTIPNLM*S*CT
QCPDTNRISW*KKIILMQ*VKNCKNTTLSIRRR
VKSMIGCMKNILEHPRKYR*RGLQ*KLLMKQLK
YLKSSVTHKNNIAKNILSDFAER
Frame 1
SD*GWGRARMADWGAEA*RAVGRRESRDGEQLFEHVLRHLTESRSSTKAT*ANDFSSSKWNEGQFC
FSSGCRMVLGGYFKGGGK*QIAGYARWDLLGPRC
LNKNAGRLYFDFAEGRQ**VNKDLSPGW*IWLF
*SSDI*FRGGAH*PLSP*ISCSVQSQT*CEADV
PSVQIPTGSVGKRR*Y*CSR*KTARIPLSVSGEE
*RV**AV*RIY*NIPGNTDEEDCNRSF**NN*N
I*RAVSHTRTT*QRIY*AISQRG
Frame 2
LIEAGGERGWLIGEPKPRERWGDVKVEMESSFLNMFSGT*QNPALPPKPPKPMTSAVPNGMKDSSV
SLQDAEWYWGDISREEVNDKLRDMPDGTFLVRD
ASTKMQGDYTLTLRKGGNNKLIKIYHRDGKYGFS
DPLTFNSVVELINHYHHESLAQYNPKLDVKLMY
PVSRYQQDQLVKEDNIDAVGKKLQEYHSQYQEK
SKEYDRLYEEYTRTSQEIQMKRTAIEAFNETIKI
FEEQCHTQEQHSKEYIERFRRE
Sequence PIK3R3.bAug05
TTCTGATTGAGGCTGGGGGAGAGCGCGGATGGCTGATTGGGGAGCCGAAGCCTAGAGAGCGGTGGGGAGACGTGAAAGTCGAGATGGAGAGCAGCTTTTTGAACATGTTCTCAGGCACTTGACAGAATCCCGCGCGATGTACAATACGGTGTGGAGTATGGACCGCGATGACGCAGACTGGAGGGAGGTGATGATGCCCT
ATTCGACAGAACTGATATTTTATATTGAAATGGATCCTCCAGCTCTTCCACCAAAGCCACCTAAGCCAATGACTTCAGCAGTTCCAAATGGAATGAAGGA
CAGTTCTGTTTCTCTTCAGGATGCAGAATGGTACTGGGGGGATATTTCAAGGGAGGAGGTAAATGACAAATTGCGGGATATGCCAGATGGGACCTTCTTG
GTCCGAGATGCCTCAACAAAAATGCAGGGAGATTATACTTTGACTTTGCGGAAGGGAGGCAATAATAAGTTAATAAAGATCTATCACCGGGATGGTAAAT
ATGGCTTTTCTGATCCTCTGACATTTAATTCCGTGGTGGAGCTCATTAACCACTATCACCATGAATCTCTTGCTCAGTACAATCCCAAACTTGATGTGAA
GCTGATGTACCCAGTGTCCAGATACCAACAGGATCAGTTGGTAAAAGAAGATAATATTGATGCAGTAGGTAAAAAACTGCAAGAATACCACTCTCAGTAT
CAGGAGAAGAGTAAAGAGTATGATAGGCTGTATGAAGAATATACTAGAACATCCCAGGAAATACAGATGAAGAGGACTGCAATAGAAGCTTTTAATGAAA
CAATTAAAATATTTGAAGAGCAGTGTCACACACAAGAACAACATAGCAAAGAATATATTGAGCGATTTCGCAGAGAGGGGAATGAAAAGGAGATTGAACG
AATTATGATGAATTATGATAAATTGAAATCACGTCTGGGTGAGATTCATGATAGCAAAATGCGTCTAGAGCAGGATTTGAAGAATCAAGCTTTGGACAAC
CGAGAAATAGATAAAAAAATGAATAGCATCAAACCTGACCTGATCCAGCTGCGAAAGATCCGAGATCAACACCTTGTATGGCTCAATCACAAAGGAGTGA
GACAGAAACGCCTGAATGTCTGGCTGGGAATTAAGAATGAGGATGCTGATGAGAACTATTTTATCAATGAGGAAGATGAAAACCTGCCCCATTATGATGA
GAAAACCTGGTTTGTTGAGGATATCAATCGAGTACAAGCAGAGGACTTGCTTTATGGGAAACCTGATGGTGCATTCTTAATTCGTGAGAGTAGCAAGAAA
GGATGCTATGCTTGCTCTGTGGTGGCCGATGGGGAAGTGAAGCACTGTGTGATCTACAGCACTGCTCGGGGCTATGGCTTTGCAGAGCCCTACAACCTGT
ACAGCTCTCTGAAGGAGCTAGTGCTCCATTACCAGCAGACATCCTTGGTTCAGCACAACGACTCCCTCAACGTCAGGCTTGCCTACCCTGTTCATGCACA
GATGCCCTCGCTTTGCAGATAAAGAGGAAGTGGGAAGAGAGGTGGTTCTCTGGCATTTTTTTCTACAGTTTTTATTAGACTACGATGAGGGCATTCTTTC
TACATAGACTGCTTGTTTTGCACAAGAAGTGATTTTGTGAATGTGAAGTGGAGAGGCCGAGCAGCAGCCGGCCGGGATGGGGGCATTAGAGGCCTGAGGT
TCTCTAGGACTCAGCCATGCCGCTGCACTGACATACTAAGCTGGAAGCAGATGTTTTTTTTGAAAGTCTGTTTCATTGGGGTTTTTGTTTTGTTTAGCCA
GACACCCTCAACAGAATATTAGGCTTGATGGTTATAGCGGGTGGGGTTGTATTTGGAAGCCTCTGAAGAGACCATGTCTTTTTAAAATCTAACTCTTGAG
AGTGCAGCAGGGGCATGGCTCTGCTGGGAGTTGTGTTTTGCTTTGGCAGTCTCTCTTCCCCCCACGAAGAAGGCTGTTTAGGTTTTGTGATAGAATGGGA
TTTGATGAAAAAGACAACCAAAGGAAAATGGGGAGGCTTGGGATTTCATTTAAATAATCTAAGCCAAGATGATAAAAAAAACCTTCAACTGAAGGTATTT
TGTTTCTTACCAACATAATTTAGGCTTCAGCATCTCACCAGCCCCTCCCTCTGAAGAAGTATTATGTTCAGAAGCCAACAAAACAGTTTGTTGCCAGACC
AATGTTTGATGGGAAAACGTGGCACTCATAGTTGAATGTATACTTCTGTACCAAAACTTGAACATAAAAAGACTAGAATTTGTGAGTTTTAGCAAACGCT
AAAATTGATCACTGTAACTAACCCCTTCTGTCCTTCCTGCCTGTTTCTCTGAGATGAGGAATAGCATTCTTTTTGTGGGGATGGTGAGCTTTGAATCATA
AAATGAAGTTGGTGCTTGTATGGTGTTTCCTTAGCCTAAAGAATGATCTGTTGTTTGAAACCTTTGTAACTTGTTTGTATGAGTAAAGAAAAGGTGCAAT
GCAGTGCTTTTAGATGGCTTGATATACCAAATAACAATATAGAACAACATTATTATATGTGCTTCCCCAAGTTTAAAGGCCCTGCAGAAATAGTAAACAT
GGTTTAATTTCCCTTCATTTCCCCCTCCTTTGCTGGATGGGGTTTTGGGAGCTATAGGTTGCTAAGGAGGGGAGTCAGATTGTGGTCAGGTGCCTCAGTA
AATCACAGACCCAGGGGCCCTGTGGTCCAGGGTGAGAGTCACACCACATTACACATGTGCTTCCATACAGTGGTTTCTGAAGCTTTTGCAGGGAGAGAAG
ATGGCTTAGTGTTTAGACTGTTAGTAGAAGCCATCTGGAAGCTTTTCTCTTTGCCTTTTTTTGTGATCCTGCCATTAAGGCTATGTGCAGTCTGCCCTCC
TGCTCCAGTGGCCTTGATTTTAGGCCAGGAATCTTCTGCTCCATGTGGCTTAAGCCTTCCAGCTGAGTGAAGCTAGGCAAATGGAGTGGGGGCAGGCATC
TATTCCTGCCCCCATCATGCCCCACACCCATCAGTCAACACTCATTTGACAAATAGAGTCCAGCTGCCTCTGAGCCAATCCTGGGACCATAATAGGCTCA
GAGTGAGTCAGCTGTTTGAACCCAAAGCTGTGCAGTCAGGCACCCTGGCTGAGCTAGAGAAGCCAGTACCTGCATCTTGGTTTATAAGGCTTACAGCTAG
GAAAGCTCTAGTTCTGGGGGTGAAAGAAAAATATTAGTTTACCTGAGCACTTATTTCCATGACAGGGTCTAAAATATGGACCATGATGTAGACACAGATT
TTTAATTTTGGAAAAACCTCCAGTTACTAGTGACGAGGATAGAAAGGGAAGTGCTTCTCTTTGGCTTTTTCTTGGTTACACTGCAGTTTCAGGATTGGGT
GAGACAGAGACAAATGAACCCCCCTCTAAAGTCATTTAACTAATAGCCAGCACATCCCTTCCCCAAACTGTCAATTGAAATCTTAACTGAAAGTTTTACT
GAATAATACCAAGCTAATTGCTGTTGGGCACACCTGGATGGCTTTGCACCTGGTGTTGAACCTGCTGAAGCAGGTGGATGCTCAAGATTACGTGCAAGGA
ATCCCTCCCATCTGGTACTAAAATTTCAGTGTGTTCTGAGTGTCTTTTAAACCAAAATGGAAATACAGATACAGGGCTGTAGTATTCAGTAATGTGTCTG
CTCCTTGTTGGGCAGACACCAGCGGTGTGCAGGGAGAGACCAAGTACCATCTTTATCTACACTTGGGCTGGCTTGTGGAGAAGGGCTGCTTTTTTTCAGT
CCTACATTCCTTCATTTTTTTTTTCATTCTTGAATTCATTGTTTTGTGGGATCTAAGACCCAGGGGTCATTTGAGAGGTTTGACAGTATCTTTTCTGACC
AGTTGCCACATGACTTGCTTGACCCTGAGCCTGTGGAAATGGCATAGGGACCAGTCTACTACCCACTGGGCCTGGTGTGTAGAGGGGGAGAGGGTAGCAA
GGTGCTTCTCTACGCCCATGACTTGGGAGCAGGTCTTGGCCTCCTTCATGAGAGTCTAGTGCCATGTCCTGTCCCATGATCTGGACCCTGGGACTGTCTT
GGCATCTTAACTGCAGTTTCAATGAGGCAGAGGGCAAAGAGAGACCAAGATCAGAGGGGTTCATTATACCCCTGGCTAGAGAACCCAGCTACTGACATGC
AAGCAGCTTGGGGCTGGCTGGACACAGGTACTAGGCCCATTGTTTCCAGGTGAAGCTTTCATCACAGAACAGTGTTGTCTCCACCTGGCCTTAGATGGCA
CGCCATGATTCGGGCCTGGATAGACTGCCTGCGTCCTTACCACTGATCTGGCCAAGAATGAGGCCCTCCCAACACTTTCACTCCCTCTCCAAGCCTTGAT
GGGACCTCCACTTATTTAGGCCTCATGTGCTTTGAAGAAGCTTTGAGAGCCAATGTGTCTTCCACGGGTCTCTTTTTTGCTACAAGTAATCAGCCCCATG
TGTTCTCTTAAACTGAGAATTGCACCTGGGCAATTCCTGTTTTCTAAGGTGGTCTCTGCTGCTATTTAACAACCCAGAGTAGGCCTCTGTGAGGCTTCAG
TGGCCTCAGAAACCAGAGGGTCCAGATAGGGGGCCTGCTTGGGCCCTCTGCTGCCAACTGCTCAAACCTGCTTTAGCTCCAGCCACTTGTGGCAAACAAC
CTCGTTTCCTTACAAATTCCAGCATGTGACTTTGGTGCCGTTACTTGTGAAAAATCTATTCTGTTGTCTTTGATGTGTCCAAGAAAATTCGTGTAGTTTA
CGTAAAAATATCTGACTCACAAGAAAGCCAACTGTATGTCTTGTGATGGGACAGTTCATAATGTAGTTGCTAGACCACTTTACAAATTGTTCTTGTCACC
AGATGTGTTCAGACATTGCTGTGCAATTGTTGGGGAGGGTAGGGGGAAAGGCGAGAGGAGATACTTATTGGTCTTTTTGTTTAATACCTTCCCCAAGAGG
GGACAGTCTGGCCAACTTGCTCCAGTAATGCAATAAAGACATTGCAATAAAGTAA
- PIK3R3.F1 (forward primer)
- PIK3R3.R1 (reverse primer)
- Single exon skipping
Frame 0
F*LRLGESADG*LGSRSLESGGET*KSRWRAAF*TCSQALDRIPRDVQYGVEYGPR*RRLEGGDDAL
FDRTDILY*NGSSSSSTKAT*ANDFSSSKWNEG
QFCFSSGCRMVLGGYFKGGGK*QIAGYARWDLL
GPRCLNKNAGRLYFDFAEGRQ**VNKDLSPGW*I
WLF*SSDI*FRGGAH*PLSP*ISCSVQSQT*CE
ADVPSVQIPTGSVGKRR*Y*CSR*KTARIPLSV
SGEE*RV**AV*RIY*NIPGNTDEEDCNRSF**N
N*NI*RAVSHTRTT*QRIY*AISQRGE*KGD*T
NYDEL**IEITSG*DS**QNASRAGFEESSFGQ
PRNR*KNE*HQT*PDPAAKDPRSTPCMAQSQRSE
TETPECLAGN*E*GC**ELFYQ*GR*KPAPL**
ENLVC*GYQSSTSRGLALWET*WCILNS*E*QE
RMLCLLCGGRWGSEALCDLQHCSGLWLCRALQPV
QLSEGASAPLPADILGSAQRLPQRQACLPCSCT
DALALQIKRKWEERWFSGIFFYSFY*TTMRAFF
LHRLLVLHKK*FCECEVERPSSSRPGWGH*RPEV
L*DSAMPLH*HTKLEADVFFESLFHWGFCFV*P
DTLNRILGLMVIAGGVVFGSL*RDHVFLKSNS*
ECSRGMALLGVVFCFGSLSSPHEEGCLGFVIEWD
LMKKTTKGKWGGLGFHLNNLSQDDKKNLQLKVF
CFLPT*FRLQHLTSPSL*RSIMFRSQQNSLLPD
QCLMGKRGTHS*MYTSVPKLEHKKTRICEF*QTL
KLITVTNPFCPSCLFL*DEE*HSFCGDGEL*II
K*SWCLYGVSLA*RMICCLKPL*LVCMSKEKVQ
CSAFRWLDIPNNNIEQHYYMCFPKFKGPAEIVNM
V*FPFISPSFAGWGFGSYRLLRRGVRLWSGASV
NHRPRGPVVQGESHTTLHMCFHTVVSEAFAGRE
DGLVFRLLVEAIWKLFSLPFFVILPLRLCAVCPP
APVALILGQESSAPCGLSLPAE*S*ANGVGAGI
YSCPHHAPHPSVNTHLTNRVQLPLSQSWDHNRL
RVSQLFEPKAVQSGTLAELEKPVPASWFIRLTAR
KALVLGVKEKY*FT*ALISMTGSKIWTMM*TQI
FNFGKTSSY**RG*KGKCFSLAFSWLHCSFRIG
*DRDK*TPL*SHLTNSQHIPSPNCQLKS*LKVLL
NNTKLIAVGHTWMALHLVLNLLKQVDAQDYVQG
IPPIWY*NFSVF*VSFKPKWKYRYRAVVFSNVS
APCWADTSGVQGETKYHLYLHLGWLVEKGCFFSV
LHSFIFFFILEFIVLWDLRPRGHLRGLTVSFLT
SCHMTCLTLSLWKWHRDQSTTHWAWCVEGERVA
RCFSTPMTWEQVLASFMRV*CHVLSHDLDPGTVL
AS*LQFQ*GRGQRETKIRGVHYTPG*RTQLLTC
KQLGAGWTQVLGPLFPGEAFITEQCCLHLALDG
TP*FGPG*TACVLTTDLAKNEALPTLSLPLQALM
GPPLI*ASCALKKL*EPMCLPRVSFLLQVISPM
CSLKLRIAPGQFLFSKVVSAAI*QPRVGLCEAS
VASETRGSR*GACLGPLLPTAQTCFSSSHLWQTT
SFPYKFQHVTLVPLLVKNLFCCL*CVQENSCSL
RKNI*LTRKPTVCLVMGQFIM*LLDHFTNCSCH
QMCSDIAVQLLGRVGGKARGDTYWSFCLIPSPRG
DSLANLLQ*CNKDIAIK*
Frame 1
SD*GWGRARMADWGAEA*RAVGRRESRDGEQLFEHVLRHLTESRAMYNTVWSMDRDDADWREVMMP
YSTELIFYIEMDPPALPPKPPKPMTSAVPNGMKD
SSVSLQDAEWYWGDISREEVNDKLRDMPDGTFL
VRDASTKMQGDYTLTLRKGGNNKLIKIYHRDGK
YGFSDPLTFNSVVELINHYHHESLAQYNPKLDVK
LMYPVSRYQQDQLVKEDNIDAVGKKLQEYHSQY
QEKSKEYDRLYEEYTRTSQEIQMKRTAIEAFNE
TIKIFEEQCHTQEQHSKEYIERFRREGNEKEIER
IMMNYDKLKSRLGEIHDSKMRLEQDLKNQALDN
REIDKKMNSIKPDLIQLRKIRDQHLVWLNHKGV
RQKRLNVWLGIKNEDADENYFINEEDENLPHYDE
KTWFVEDINRVQAEDLLYGKPDGAFLIRESSKK
GCYACSVVADGEVKHCVIYSTARGYGFAEPYNL
YSSLKELVLHYQQTSLVQHNDSLNVRLAYPVHAQ
MPSLCR*RGSGKRGGSLAFFSTVFIRLR*GHSF
YIDCLFCTRSDFVNVKWRGRAAAGRDGGIRGLR
FSRTQPCRCTDILSWKQMFFLKVCFIGVFVLFSQ
TPSTEY*A*WL*RVGLYLEASEETMSF*NLTLE
SAAGAWLCWELCFALAVSLPPTKKAV*VL**NG
I**KRQPKENGEAWDFI*II*AKMIKKTFN*RYF
VSYQHNLGFSISPAPPSEEVLCSEANKTVCCQT
NV*WENVALIVECILLYQNLNIKRLEFVSFSKR
*N*SL*LTPSVLPACFSEMRNSILFVGMVSFES*
NEVGACMVFP*PKE*SVV*NLCNLFV*VKKRCN
AVLLDGLIYQITI*NNIIICASPSLKALQK**T
WFNFPSFPPPLLDGVLGAIGC*GGESDCGQVPQ*
ITDPGALWSRVRVTPHYTCASIQWFLKLLQGEK
MA*CLDC**KPSGSFSLCLFL*SCH*GYVQSAL
LLQWP*F*ARNLLLHVA*AFQLSEARQMEWGQAS
IPAPIMPHTHQSTLI*QIESSCL*ANPGTIIGS
E*VSCLNPKLCSQAPWLS*RSQYLHLGL*GLQL
GKL*FWG*KKNISLPEHLFP*QGLKYGP*CRHRF
LILEKPPVTSDEDRKGSASLWLFLGYTAVSGLG
ETETNEPPSKVI*LIASTSLPQTVN*NLN*KFY
*IIPS*LLLGTPGWLCTWC*TC*SRWMLKITCKE
SLPSGTKISVCSECLLNQNGNTDTGL*YSVMCL
LLVGQTPAVCRERPSTIFIYTWAGLWRRAAFFQ
SYIPSFFFSFLNSLFCGI*DPGVI*EV*QYLF*P
VAT*LA*P*ACGNGIGTSLLPTGPGV*RGRG*Q
GASLRP*LGSRSWPPS*ESSAMSCPMIWTLGLS
WHLNCSFNEAEGKERPRSEGFIIPLAREPSY*HA
SSLGLAGHRY*AHCFQVKLSSQNSVVSTWP*MA
RHDSGLDRLPASLPLIWPRMRPSQHFHSLSKP*
WDLHLFRPHVL*RSFESQCVFHGSLFCYK*SAPC
VLLN*ELHLGNSCFLRWSLLLFNNPE*ASVRLQ
WPQKPEGPDRGPAWALCCQLLKPALAPATCGKQ
PRFLTNSSM*LWCRYL*KIYSVVFDVSKKIRVVY
VKISDSQESQLYVL*WDSS*CSC*TTLQIVLVT
RCVQTLLCNCWGG*GERREEILIGLFV*YLPQE
GTVWPTCSSNAIKTLQ*S
Frame 2
LIEAGGERGWLIGEPKPRERWGDVKVEMESSFLNMFSGT*QNPARCTIRCGVWTAMTQTGGR**CP
IRQN*YFILKWILQLFHQSHLSQ*LQQFQME*R
TVLFLFRMQNGTGGIFQGRR*MTNCGICQMGPSW
SEMPQQKCREIIL*LCGREAIIS**RSITGMVN
MAFLIL*HLIPWWSSLTTITMNLLLSTIPNLM*
S*CTQCPDTNRISW*KKIILMQ*VKNCKNTTLSI
RRRVKSMIGCMKNILEHPRKYR*RGLQ*KLLMK
QLKYLKSSVTHKNNIAKNILSDFAERGMKRRLN
EL**IMIN*NHVWVRFMIAKCV*SRI*RIKLWTT
EK*IKK*IASNLT*SSCERSEINTLYGSITKE*
DRNA*MSGWELRMRMLMRTILSMRKMKTCPIMM
RKPGLLRISIEYKQRTCFMGNLMVHS*FVRVARK
DAMLALWWPMGK*STV*STALLGAMALQSPTTC
TAL*RS*CSITSRHPWFSTTTPSTSGLPTLFMH
RCPRFADKEEVGREVVLWHFFLQFLLDYDEGILS
T*TACFAQEVIL*M*SGEAEQQPAGMGALEA*G
SLGLSHAAALTY*AGSRCFF*KSVSLGFLFCLA
RHPQQNIRLDGYSGWGCIWKPLKRPCLFKI*LLR
VQQGHGSAGSCVLLWQSLFPPRRRLFRFCDRMG
FDEKDNQRKMGRLGISFK*SKPR**KKPSTEGI
LFLTNII*ASASHQPLPLKKYYVQKPTKQFVARP
MFDGKTWHS*LNVYFCTKT*T*KD*NL*VLANA
KIDHCN*PLLSFLPVSLR*GIAFFLWGW*ALNH
KMKLVLVWCFLSLKNDLLFETFVTCLYE*RKGAM
QCF*MA*YTK*QYRTTLLYVLPQV*RPCRNSKH
GLISLHFPLLCWMGFWEL*VAKEGSQIVVRCLS
KSQTQGPCGPG*ESHHITHVLPYSGF*SFCRERR
WLSV*TVSRSHLEAFLFAFFCDPAIKAMCSLPS
CSSGLDFRPGIFCSMWLKPSS*VKLGKWSGGRH
LFLPPSCPTPISQHSFDK*SPAASEPILGP**AQ
SESAV*TQSCAVRHPG*AREASTCILVYKAYS*
ESSSSGGERKILVYLSTYFHDRV*NMDHDVDTD
F*FWKNLQLLVTRIEREVLLFGFFLVTLQFQDWV
RQRQMNPPLKSFN**PAHPFPKLSIEILTESFT
E*YQANCCWAHLDGFAPGVEPAEAGGCSRLRAR
NPSHLVLKFQCVLSVF*TKMEIQIQGCSIQ*CVC
SLLGRHQRCAGRDQVPSLSTLGLACGEGLLFFS
PTFLHFFFHS*IHCFVGSKTQGSFERFDSIFSD
QLPHDLLDPEPVEMA*GPVYYPLGLVCRGGEGSK
VLLYAHDLGAGLGLLHESLVPCPVP*SGPWDCL
GILTAVSMRQRAKRDQDQRGSLYPWLENPATDM
QAAWGWLDTGTRPIVSR*SFHHRTVLSPPGLRWH
AMIRAWIDCLRPYH*SGQE*GPPNTFTPSPSLD
GTSTYLGLMCFEEALRANVSSTGLFFATSNQPH
VFS*TENCTWAIPVF*GGLCCYLTTQSRPL*GFS
GLRNQRVQIGGLLGPSAANCSNLL*LQPLVANN
LVSLQIPACDFGAVTCEKSILLSLMCPRKFV*F
T*KYLTHKKANCMSCDGTVHNVVARPLYKLFLSP
DVFRHCCAIVGEGRGKGERRYLLVFLFNTFPKR
GQSGQLAPVMQ*RHCNKV
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