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Sequence ABCB1.fAug05
CACCCAAACTTATCCTTGGGTTTTCACTGATTAGTGCTTTCAAGCCTGCCTGCCTTAGTTCATGTAGCTCCTCCTCTGGTACTGGGATAAACACTTGTATTACCATTTTAAAGGCTATCATTACTCTTTACCTGTGAAGAGTAGAACATGAAGAAATCTACTTTATTCAGATATTCTCCAGATTCCTAAAGATTAGAGAT
CATTTCTCATTCTCCTAGGAGTACTCACTTCAGGAAGCAACCAGAGAGGTGCAACGGAAGCCAGAACATTCCTCCTGGAAATTCAACCTGTTTCGCAGTT
TCTCGAGGAATCAGCATTCAGTCAATCCGGGCCGGGAGCAGTCATCTGTGGTCGGAATGGATCTTGAAGGGGACCGCAATGGAGGAGCAAAGAAGAAGAA
CTTTTTTAAACTGAACAATAAAAGGTAACTAGCTTGTTTCATTTTCATAGTTTACATAGTTGCGAGATTTGAGTAATTTATTTCTAGCCTCCAGCTCTGA
AATAAATGACATGTTGTTGTTTTTAATTATTTTTAAGAAACGCAAGCTAGCCTTTGGAATCAATATCCCTGCTTAGAGCAGAAGTTTGTTGGCTGAGTGG
AGCACAGCATATGCATTTTCCCTGTCTTTTTTGTTCTTTCTTTTAATGATACATAATATTTTACATATTTATGAAATGGGGTACATGGAAGCGTTTTTTA
CATGCCCGGA
- ABCB1.F1 (forward primer)
- ABCB1.R3 (reverse primer)
- Single exon skipping
Frame 0
HPNLSLGFH*LVLSSLPALVHVAPPLVLG*TLVLPF*RLSLLFTCEE*NMKKSTLFRYSPDS*RLEI
ISHSPRSTHFRKQPERCNGSQNIPPGNSTCFAV
SRGISIQSIRAGSSHLWSEWILKGTAMEEQRRR
TFLN*TIKGN*LVSFS*FT*LRDLSNLFLASSSE
INDMLLFLIIFKKRKLAFGINIPA*SRSLLAEW
STAYAFSLSFLFFLLMIHNILHIYEMGYMEAFF
TCP
Frame 1
TQTYPWVFTD*CFQACLP*FM*LLLWYWDKHLYYHFKGYHYSLPVKSRT*RNLLYSDILQIPKD*R
SFLILLGVLTSGSNQRGATEARTFLLEIQPVSQF
LEESAFSQSGPGAVICGRNGS*RGPQWRSKEEE
LF*TEQ*KVTSLFHFHSLHSCEI*VIYF*PPAL
K*MTCCCF*LFLRNAS*PLESISLLRAEVCWLSG
AQHMHFPCLFCSFF**YIIFYIFMKWGTWKRFL
HAR
Frame 2
PKLILGFSLISAFKPACLSSCSSSSGTGINTCITILKAIITLYL*RVEHEEIYFIQIFSRFLKIRD
HFSFS*EYSLQEATREVQRKPEHSSWKFNLFRS
FSRNQHSVNPGREQSSVVGMDLEGDRNGGAKKKN
FFKLNNKR*LACFIFIVYIVARFE*FISSLQL*
NK*HVVVFNYF*ETQASLWNQYPCLEQKFVG*V
EHSICIFPVFFVLSFNDT*YFTYL*NGVHGSVFY
MPG
Sequence ABCB1.eAug05
CACCCAAACTTATCCTTGGGTTTTCACTGATTAGTGCTTTCAAGCCTGCCTGCCTTAGTTCATGTAGCTCCTCCTCTGGTACTGGGATAAACACTTGTATTACCATTTTAAAGGCTATCATTACTCTTTACCTGTGAAGAGTAGAACATGAAGAAATCTACTTTATTCAGATATTCTCCAGATTCCTAAAGATTAGAGAT
CATTTCTCATTCTCCTAGGAGTACTCACTTCAGGAAGCAACCAGAGAGGTGCAACGGAAGCCAGAACATTCCTCCTGGAAATTCAACCTGTTTCGCAGTT
TCTCGAGGAATCAGCATTCAGTCAATCCGGGCCGGGAGCAGTCATCTGTGGTCTTTCCACTAAAGTCGGAGTATCTTCTTCCAAAATTTCACGTCTTGGT
GGCCGTTCCAAGGAGCGCGAGGTCGGAATGGATCTTGAAGGGGACCGCAATGGAGGAGCAAAGAAGAAGAACTTTTTTAAACTGAACAATAAAAGGTAAC
TAGCTTGTTTCATTTTCATAGTTTACATAGTTGCGAGATTTGAGTAATTTATTTCTAGCCTCCAGCTCTGAAATAAATGACATGTTGTTGTTTTTAATTA
TTTTTAAGAAACGCAAGCTAGCCTTTGGAATCAATATCCCTGCTTAGAGCAGAAGTTTGTTGGCTGAGTGGAGCACAGCATATGCATTTTCCCTGTCTTT
TTTGTTCTTTCTTTTAATGATACATAATATTTTACATATTTATGAAATGGGGTACATGGAAGCGTTTTTTACATGCCCGGA
- ABCB1.F1 (forward primer)
- ABCB1.R3 (reverse primer)
- Single exon skipping
Frame 0
HPNLSLGFH*LVLSSLPALVHVAPPLVLG*TLVLPF*RLSLLFTCEE*NMKKSTLFRYSPDS*RLEI
ISHSPRSTHFRKQPERCNGSQNIPPGNSTCFAV
SRGISIQSIRAGSSHLWSFH*SRSIFFQNFTSW
WPFQGARGRNGS*RGPQWRSKEEELF*TEQ*KVT
SLFHFHSLHSCEI*VIYF*PPALK*MTCCCF*L
FLRNAS*PLESISLLRAEVCWLSGAQHMHFPCL
FCSFF**YIIFYIFMKWGTWKRFLHAR
Frame 1
TQTYPWVFTD*CFQACLP*FM*LLLWYWDKHLYYHFKGYHYSLPVKSRT*RNLLYSDILQIPKD*R
SFLILLGVLTSGSNQRGATEARTFLLEIQPVSQF
LEESAFSQSGPGAVICGLSTKVGVSSSKISRLG
GRSKEREVGMDLEGDRNGGAKKKNFFKLNNKR*
LACFIFIVYIVARFE*FISSLQL*NK*HVVVFNY
F*ETQASLWNQYPCLEQKFVG*VEHSICIFPVF
FVLSFNDT*YFTYL*NGVHGSVFYMPG
Frame 2
PKLILGFSLISAFKPACLSSCSSSSGTGINTCITILKAIITLYL*RVEHEEIYFIQIFSRFLKIRD
HFSFS*EYSLQEATREVQRKPEHSSWKFNLFRS
FSRNQHSVNPGREQSSVVFPLKSEYLLPKFHVLV
AVPRSARSEWILKGTAMEEQRRRTFLN*TIKGN
*LVSFS*FT*LRDLSNLFLASSSEINDMLLFLI
IFKKRKLAFGINIPA*SRSLLAEWSTAYAFSLSF
LFFLLMIHNILHIYEMGYMEAFFTCP
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