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Sequences

Sequence ABCB1.fAug05

CACCCAAACTTATCCTTGGGTTTTCACTGATTAGTGCTTTCAAGCCTGCCTGCCTTAGTTCATGTAGCTCCTCCTCTGGTACTGGGATAAACACTTGTAT
TACCATTTTAAAGGCTATCATTACTCTTTACCTGTGAAGAGTAGAACATGAAGAAATCTACTTTATTCAGATATTCTCCAGATTCCTAAAGATTAGAGAT
CATTTCTCATTCTCCTAGGAGTACTCACTTCAGGAAGCAACCAGAGAGGTGCAACGGAAGCCAGAACATTCCTCCTGGAAATTCAACCTGTTTCGCAGTT
TCTCGAGGAATCAGCATTCAGTCAATCCGGGCCGGGAGCAGTCATCTGTGGTCGGAATGGATCTTGAAGGGGACCGCAATGGAGGAGCAAAGAAGAAGAA
CTTTTTTAAACTGAACAATAAAAGGTAACTAGCTTGTTTCATTTTCATAGTTTACATAGTTGCGAGATTTGAGTAATTTATTTCTAGCCTCCAGCTCTGA
AATAAATGACATGTTGTTGTTTTTAATTATTTTTAAGAAACGCAAGCTAGCCTTTGGAATCAATATCCCTGCTTAGAGCAGAAGTTTGTTGGCTGAGTGG
AGCACAGCATATGCATTTTCCCTGTCTTTTTTGTTCTTTCTTTTAATGATACATAATATTTTACATATTTATGAAATGGGGTACATGGAAGCGTTTTTTA
CATGCCCGGA
  • ABCB1.F2 (forward primer)
  • ABCB1.R4 (reverse primer)
  • Single exon skipping

Frame 0

HPNLSLGFH*LVLSSLPALVHVAPPLVLG*TLV
LPF*RLSLLFTCEE*NMKKSTLFRYSPDS*RLEI
ISHSPRSTHFRKQPERCNGSQNIPPGNSTCFAV
SRGISIQSIRAGSSHLWSEWILKGTAMEEQRRR
TFLN*TIKGN*LVSFS*FT*LRDLSNLFLASSSE
INDMLLFLIIFKKRKLAFGINIPA*SRSLLAEW
STAYAFSLSFLFFLLMIHNILHIYEMGYMEAFF
TCP

Frame 1

TQTYPWVFTD*CFQACLP*FM*LLLWYWDKHLY
YHFKGYHYSLPVKSRT*RNLLYSDILQIPKD*R
SFLILLGVLTSGSNQRGATEARTFLLEIQPVSQF
LEESAFSQSGPGAVICGRNGS*RGPQWRSKEEE
LF*TEQ*KVTSLFHFHSLHSCEI*VIYF*PPAL
K*MTCCCF*LFLRNAS*PLESISLLRAEVCWLSG
AQHMHFPCLFCSFF**YIIFYIFMKWGTWKRFL
HAR

Frame 2

PKLILGFSLISAFKPACLSSCSSSSGTGINTCI
TILKAIITLYL*RVEHEEIYFIQIFSRFLKIRD
HFSFS*EYSLQEATREVQRKPEHSSWKFNLFRS
FSRNQHSVNPGREQSSVVGMDLEGDRNGGAKKKN
FFKLNNKR*LACFIFIVYIVARFE*FISSLQL*
NK*HVVVFNYF*ETQASLWNQYPCLEQKFVG*V
EHSICIFPVFFVLSFNDT*YFTYL*NGVHGSVFY
MPG

Sequence ABCB1.eAug05

CACCCAAACTTATCCTTGGGTTTTCACTGATTAGTGCTTTCAAGCCTGCCTGCCTTAGTTCATGTAGCTCCTCCTCTGGTACTGGGATAAACACTTGTAT
TACCATTTTAAAGGCTATCATTACTCTTTACCTGTGAAGAGTAGAACATGAAGAAATCTACTTTATTCAGATATTCTCCAGATTCCTAAAGATTAGAGAT
CATTTCTCATTCTCCTAGGAGTACTCACTTCAGGAAGCAACCAGAGAGGTGCAACGGAAGCCAGAACATTCCTCCTGGAAATTCAACCTGTTTCGCAGTT
TCTCGAGGAATCAGCATTCAGTCAATCCGGGCCGGGAGCAGTCATCTGTGGTCTTTCCACTAAAGTCGGAGTATCTTCTTCCAAAATTTCACGTCTTGGT
GGCCGTTCCAAGGAGCGCGAG
GTCGGAATGGATCTTGAAGGGGACCGCAATGGAGGAGCAAAGAAGAAGAACTTTTTTAAACTGAACAATAAAAGGTAAC
TAGCTTGTTTCATTTTCATAGTTTACATAGTTGCGAGATTTGAGTAATTTATTTCTAGCCTCCAGCTCTGAAATAAATGACATGTTGTTGTTTTTAATTA
TTTTTAAGAAACGCAAGCTAGCCTTTGGAATCAATATCCCTGCTTAGAGCAGAAGTTTGTTGGCTGAGTGGAGCACAGCATATGCATTTTCCCTGTCTTT
TTTGTTCTTTCTTTTAATGATACATAATATTTTACATATTTATGAAATGGGGTACATGGAAGCGTTTTTTACATGCCCGGA
  • ABCB1.F2 (forward primer)
  • ABCB1.R4 (reverse primer)
  • Single exon skipping

Frame 0

HPNLSLGFH*LVLSSLPALVHVAPPLVLG*TLV
LPF*RLSLLFTCEE*NMKKSTLFRYSPDS*RLEI
ISHSPRSTHFRKQPERCNGSQNIPPGNSTCFAV
SRGISIQSIRAGSSHLWSFH*SRSIFFQNFTSW
WPFQGAR
GRNGS*RGPQWRSKEEELF*TEQ*KVT
SLFHFHSLHSCEI*VIYF*PPALK*MTCCCF*L
FLRNAS*PLESISLLRAEVCWLSGAQHMHFPCL
FCSFF**YIIFYIFMKWGTWKRFLHAR

Frame 1

TQTYPWVFTD*CFQACLP*FM*LLLWYWDKHLY
YHFKGYHYSLPVKSRT*RNLLYSDILQIPKD*R
SFLILLGVLTSGSNQRGATEARTFLLEIQPVSQF
LEESAFSQSGPGAVICGLSTKVGVSSSKISRLG
GRSKERE
VGMDLEGDRNGGAKKKNFFKLNNKR*
LACFIFIVYIVARFE*FISSLQL*NK*HVVVFNY
F*ETQASLWNQYPCLEQKFVG*VEHSICIFPVF
FVLSFNDT*YFTYL*NGVHGSVFYMPG

Frame 2

PKLILGFSLISAFKPACLSSCSSSSGTGINTCI
TILKAIITLYL*RVEHEEIYFIQIFSRFLKIRD
HFSFS*EYSLQEATREVQRKPEHSSWKFNLFRS
FSRNQHSVNPGREQSSVVFPLKSEYLLPKFHVLV
AVPRSAR
SEWILKGTAMEEQRRRTFLN*TIKGN
*LVSFS*FT*LRDLSNLFLASSSEINDMLLFLI
IFKKRKLAFGINIPA*SRSLLAEWSTAYAFSLSF
LFFLLMIHNILHIYEMGYMEAFFTCP

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