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Sequences

Sequence PTK6.dAug05

PTK6.F8 (forward primer)
PTK6.R8 (reverse primer)
Single exon skipping

Frame 0

CHAQLWVLQLGHSLVLPLRPPAMVSRDQAHLGP KYVGLWDFKSRTDEELSFRAGDVFHVARKEEQWW WATLLDEAGGAVAQGYVPHNYLAERETVESEPA GHAGCAALQDLAACRGPAAPERGGVLPQPARAC ELPQGPEPVPRPAAGRALPEARA*APAPLG*LGE AEGGVHALQEAGVRLLWGGLRGALERPGPGGH* GDFSRQPPAPADAAVGDPGHEEAAAQTHPGAVR RGVRGGPRVHHHGAHGQGQPAGAAPRL**ESPAR FGAAGHRLAGG*GHVLPGVAELHPPGPGRQEHP RRG

Frame 1

ATPSSGCSSWATAWSCRCARPPWCPGTRLTWAP SMWASGTSSPGRTRS*ASARGTSSTWPGRRSSG GGPRCWTRRVGPWPRAMCPTTTWPRGRRWSRNLR DTQAVRHYKIWRRAGGRLHLNEAVSFLSLPELV NYHRAQSLSHGLRLAAPCRKHEPEPLPHWDDWE RPREEFTLCRKLGSGYFGEVFEGLWKDRVQVAIK VISRDNLLHQQMLQSEIQAMKKLRHKHILALYA VVSVGDPVYIITELMAKGSLLELLRDSDEKVLP VSELLDIAWQVAEGMCYLESQNYIHRDLAARNIL VGE

Frame 2

PRPALGAPAGPQPGPAAAPARHGVPGPGSPGPQ VCGPLGLQVPDGRGAELPRGGRLPRGQEGGAVV VGHAAGRGGWGRGPGLCAPQLPGREGDGGVGTC GTRRLCGTTRSGGVPGAGCT*TRRCPSSACPSL* TTTGPRACPTACGWPRPAGSTSLSPCPIGMTGR GRGRSSRSAGSWGPATLGRSSRGSGKTGSRWPL R*FLETTSCTSRCCSRRSRP*RSCGTNTSWRCTP WCPWGTPCTSSRSSWPRAACWSCSATLMRKSCP FRSCWTSPGRWLRACVTWSRRITSTGTWPPGTS SSG

Sequence PTK6.bAug05

TGCCACGCCCAGCTCTGGGTGCTCCAGCTGGGCCACAGCCTGGTCCTGCCGCTGCGCCCGCCCGCCATGGTGTCCCGGGACCAGGCTCACCTGGGCCCCA AGTATGTGGGCCTCTGGGACTTCAAGTCCCGGACGGACGAGGAGCTGAGCTTCCGCGCGGGGGACGTCTTCCACGTGGCCAGGAAGGAGGAGCAGTGGTG GTGGGCCACGCTGCTGGACGAGGCGGGTGGGGCCGTGGCCCAGGGCTATGTGCCCCACAACTACCTGGCCGAGAGGGAGACGGTGGAGTCGGAACCGTGG TTCTTTGGCTGCATCTCCCGCTCGGAAGCTGTGCGTCGGCTGCAGGCCGAGGGCAACGCCACGGGCGCCTTCCTGATCAGGTGCGGGACACGCAGGCTGT GCGGCACTACAAGATCTGGCGGCGTGCCGGGGGCCGGCTGCACCTGAACGAGGCGGTGTCCTTCCTCAGCCTGCCCGAGCTTGTGAACTACCACAGGGCC CAGAGCCTGTCCCACGGCCTGCGGCTGGCCGCGCCCTGCCGGAAGCACGAGCCTGAGCCCCTGCCCCATTGGGATGACTGGGAGAGGCCGAGGGAGGAGT TCACGCTCTGCAGGAAGCTGGGGTCCGGCTACTTTGGGGAGGTCTTCGAGGGGCTCTGGAAAGACCGGGTCCAGGTGGCCATTAAGGTGATTTCTCGAGA CTCTGATGAGAAAGTCCTGCCCGTTTCGGAGCTGCTGGACATCGCCTGGCAGGTGGCTGAGGGCATGTGTTACCTGGAGTCGCAGAATTACATCCACCGG GACCTGGCCGCCAGGAACATCCTCGTCGGGGAAAACACCCTCTGCAAAGTTGGGGACTTCGGGTTAGCCAGGCTTATCAAGGAGGACGTCTACCTCTCCC ATGACCACAATATCCCCTACAAGTGGACGGCCCCTGAAGCGCTCTCCCGAGGCCATTACTCCACCAAATCCGACGTCTGGTCCTTTGGGATTCTCCTGCA TGAGATGTTCAGCAGGGGTCAGGTGCCCTACCCAGGCATGTCCAACCATGAGGCCTTCCTGAGGGTGGACGCCGGCTACCGCATGCCCTGCCCTCTGGAG TGCCCGCCCAGCGTGCACAAGCTGATGCTGACATGCTGGTGCAGGGACCCCGAGCAGAGACCCTGCTTCAAGGCCCTGCGGGAGAGGCTCTCCAGCTTCA CCAGCTACGAGAACCCGACCTGAGCTGCTGTGGAGCGGGCATGGCCGGGCCCTGCTGAGGAGGGGCCTGGGCAGAGGGCCTGGACCTGGGATCAAGGCCC ACGCGCTTCCCTGGGGTTTACTGAGGTGATGGGTGCAGGAAAGGTTCACAAATGTGGAGTGTCTGCGTCCAATACACGCGTGTGCTCCTCTCCTTACTCC ATCGTGTGTGCCTTGGGTCTCAGCTGCTGACACGCAGCCTGCTCTGGAGCCTGCAGATGAGATCCGGGAGACTGACACGAAGCCAGCAGAGGTCAGAGGG GACTCTGACCACAGCCCGCTCTCTGGCTGTCTGTCTGCAGTGCCCGGCTGAGGGTGGGAGGCAAACACGCCTTGTTCCTGCTCTTCCCAGTTCAGCTTGG TGGGAGAAAGTCATTCGCGTGGCTCGGGACGCTCATGTAAATTTGGTTTTGGTGCTCAAGGGTTCTTTCCTCCCAGGGGCAGGTGTTTCTTTCCTGTTTG TCTTGTGTCTTGAGAGCTTGGCCTTATGACCAGTGAGAACTCTCTCCCTGGTCTCTGCCAGCCCAAGCATCACTGCCCGAGGCGCCAGCTCAGTTTCACC GTCCACGTCCACAAGGGGCTTTTCCCACCTTCACCTTTGTCGCTGGGTCAGTGCTGGAAAGCGCCCCTCACTCCTGCGCTGACAAGGGCCCTTCTCTACT GTCTGTGGGGTGGTTCCGGGCTGGGGGGGCTGCCTCCTTTGCACCTGATTTTGAAGGTGTCTCTTTCATCCATGGTTAAGTCATAAAAAGCTTATTGGTT TTGGTTTTGACTCACCTGAAAGTTTTTTTGGTTTAAAAGAAGAATAGGCGGGGCACGGTGGCTCATGCCTGTAATCCCAGCACTTTGGGAGGCTGAGGCA GGTGGATCACGAGGTCAGGAGATCGACACCATCCTGGCTAACACGGTGAAACCCCGTCTCTACTAAAAAATACAAAAAATTAGCTGGGTGTGGTGGTGGG GGTGGGCGCCTGTAGTCCCAGCTACGTGGGAGGCTGAGGCAGCAGACTGGTGTGAACCCGGGAGGTGGAGCTTGCAGTGAGCCGAGATCGCGCCACTGCA CTCCAGCCTGGGCGACAGAGCGAGACTCCATCTCAAAAAAAAAAAAAAAAAAAAGAAAGAAAGAAAAATAATTTTGGGAGTTTCTGGAAAGGTACTAGGA TTTCTCAAAAGGATTTGTCTTCTGCCTTGTGAAAGACAGATGTCAGACTAATCAGGCTTATCCGATGTGCTACATGAGATGGAAAGCGTGTGAAATAGTA AGTCACACTAAGTCTTCTGGAGGTTCTATTTACGGGTTTGGTTTTGATATGAATGTTGCAGAAACTCTATAAAATTCCTAGAAATCTGATACGTTATCCT ATGATATATATCCTATCTCACATGCTATTCCTAGAAATCTGGTGCAATGTTATCAGTCATAATTTTGGTTATTACATTAAAATGCTGCATGCCACAGAAA TAACCAAGTTTCCTTGCCAACCGTGTCACGAATATAATAAACTCTCATCAGATCCTGAGCCATGGCTATCTTAAGTCTTCGGTCATTCACAGTTATTATC TTACTTTGATTTTTTCTGAAAGCTTTGCAATCAGCTAGTCCCAAATTGTTTATTCTTCAAAGAGATTCCTGGGAAGGATTCTGACAGGTGCTCTGGAGCA CAGGTTTCTGGTTCAGGTCATAGCCTTGGA

PTK6.F8 (forward primer)
PTK6.R8 (reverse primer)
Single exon skipping

Frame 0

CHAQLWVLQLGHSLVLPLRPPAMVSRDQAHLGP KYVGLWDFKSRTDEELSFRAGDVFHVARKEEQWW WATLLDEAGGAVAQGYVPHNYLAERETVESEPW FFGCISRSEAVRRLQAEGNATGAFLIRCGTRRL CGTTRSGGVPGAGCT*TRRCPSSACPSL*TTTGP RACPTACGWPRPAGSTSLSPCPIGMTGRGRGRS SRSAGSWGPATLGRSSRGSGKTGSRWPLR*FLE TLMRKSCPFRSCWTSPGRWLRACVTWSRRITSTG TWPPGTSSSGKTPSAKLGTSG*PGLSRRTSTSP MTTISPTSGRPLKRSPEAITPPNPTSGPLGFSC MRCSAGVRCPTQACPTMRPS*GWTPATACPALWS ARPACTS*C*HAGAGTPSRDPASRPCGRGSPAS PATRTRPELLWSGHGRALLRRGLGRGPGPGIKA HALPWGLLR*WVQERFTNVECLRPIHACAPLLTP SCVPWVSAADTQPALEPADEIRETDTKPAEVRG DSDHSPLSGCLSAVPG*GWEANTPCSCSSQFSL VGESHSRGSGRSCKFGFGAQGFFPPRGRCFFPVC LVS*ELGLMTSENSLPGLCQPKHHCPRRQLSFT VHVHKGLFPPSPLSLGQCWKAPLTPALTRALLY CLWGGSGLGGLPPLHLILKVSLSSMVKS*KAYWF WF*LT*KFFWFKRRIGGARWLMPVIPALWEAEA GGSRGQEIDTILANTVKPRLY*KIQKISWVWWW GWAPVVPATWEAEAADWCEPGRWSLQ*AEIAPLH SSLGDRARLHLKKKKKKKKERKIILGVSGKVLG FLKRICLLPCERQMSD*SGLSDVLHEMESV*NS KSH*VFWRFYLRVWF*YECCRNSIKFLEI*YVIL *YISYLTCYS*KSGAMLSVIILVITLKCCMPQK *PSFLANRVTNIINSHQILSHGYLKSSVIHSYY LTLIFSESFAIS*SQIVYSSKRFLGRILTGALEH RFLVQVIAL

Frame 1

ATPSSGCSSWATAWSCRCARPPWCPGTRLTWAP SMWASGTSSPGRTRS*ASARGTSSTWPGRRSSG GGPRCWTRRVGPWPRAMCPTTTWPRGRRWSRNRG SLAASPARKLCVGCRPRATPRAPS*SGAGHAGC AALQDLAACRGPAAPERGGVLPQPARACELPQG PEPVPRPAAGRALPEARA*APAPLG*LGEAEGGV HALQEAGVRLLWGGLRGALERPGPGGH*GDFSR L**ESPARFGAAGHRLAGG*GHVLPGVAELHPP GPGRQEHPRRGKHPLQSWGLRVSQAYQGGRLPLP *PQYPLQVDGP*SALPRPLLHQIRRLVLWDSPA *DVQQGSGALPRHVQP*GLPEGGRRLPHALPSG VPAQRAQADADMLVQGPRAETLLQGPAGEALQLH QLREPDLSCCGAGMAGPC*GGAWAEGLDLGSRP TRFPGVY*GDGCRKGSQMWSVCVQYTRVLLSLL HRVCLGSQLLTRSLLWSLQMRSGRLTRSQQRSEG TLTTARSLAVCLQCPAEGGRQTRLVPALPSSAW WEKVIRVARDAHVNLVLVLKGSFLPGAGVSFLF VLCLESLAL*PVRTLSLVSASPSITARGASSVSP STSTRGFSHLHLCRWVSAGKRPSLLR*QGPFST VCGVVPGWGGCLLCT*F*RCLFHPWLSHKKLIG FGFDSPESFFGLKEE*AGHGGSCL*SQHFGRLRQ VDHEVRRSTPSWLTR*NPVSTKKYKKLAGCGGG GGRL*SQLRGRLRQQTGVNPGGGACSEPRSRHC TPAWATERDSISKKKKKKRKKEK*FWEFLERY*D FSKGFVFCLVKDRCQTNQAYPMCYMRWKACEIV SHTKSSGGSIYGFGFDMNVAETL*NS*KSDTLS YDIYPISHAIPRNLVQCYQS*FWLLH*NAACHRN NQVSLPTVSRI**TLIRS*AMAILSLRSFTVII LL*FFLKALQSASPKLFILQRDSWEGF*QVLWS TGFWFRS*PW

Frame 2

PRPALGAPAGPQPGPAAAPARHGVPGPGSPGPQ VCGPLGLQVPDGRGAELPRGGRLPRGQEGGAVV VGHAAGRGGWGRGPGLCAPQLPGREGDGGVGTV VLWLHLPLGSCASAAGRGQRHGRLPDQVRDTQAV RHYKIWRRAGGRLHLNEAVSFLSLPELVNYHRA QSLSHGLRLAAPCRKHEPEPLPHWDDWERPREE FTLCRKLGSGYFGEVFEGLWKDRVQVAIKVISRD SDEKVLPVSELLDIAWQVAEGMCYLESQNYIHR DLAARNILVGENTLCKVGDFGLARLIKEDVYLS HDHNIPYKWTAPEALSRGHYSTKSDVWSFGILLH EMFSRGQVPYPGMSNHEAFLRVDAGYRMPCPLE CPPSVHKLMLTCWCRDPEQRPCFKALRERLSSF TSYENPT*AAVERAWPGPAEEGPGQRAWTWDQGP RASLGFTEVMGAGKVHKCGVSASNTRVCSSPYS IVCALGLSC*HAACSGACR*DPGD*HEASRGQR GL*PQPALWLSVCSARLRVGGKHALFLLFPVQLG GRKSFAWLGTLM*IWFWCSRVLSSQGQVFLSCL SCVLRAWPYDQ*ELSPWSLPAQASLPEAPAQFH RPRPQGAFPTFTFVAGSVLESAPHSCADKGPSLL SVGWFRAGGAASFAPDFEGVSFIHG*VIKSLLV LVLTHLKVFLV*KKNRRGTVAHACNPSTLGG*G RWITRSGDRHHPG*HGETPSLLKNTKN*LGVVVG VGACSPSYVGG*GSRLV*TREVELAVSRDRATA LQPGRQSETPSQKKKKKKERKKNNFGSFWKGTR ISQKDLSSAL*KTDVRLIRLIRCAT*DGKRVK** VTLSLLEVLFTGLVLI*MLQKLYKIPRNLIRYP MIYILSHMLFLEIWCNVISHNFGYYIKMLHATE ITKFPCQPCHEYNKLSSDPEPWLS*VFGHSQLLS YFDFF*KLCNQLVPNCLFFKEIPGKDSDRCSGA QVSGSGHSLG