×
1 warning:
  • Access restricted to public data.
    Please sign in at Rnomics Platform to access your data.
Navigation
Sequences

Sequence HSD17B1.fAug05

AGTTAGGTGGGACTTGGGTTGGGGTAGAGTCAGGTTGTGACCTGCACTCCATTAGCCATGAGACCTCAGGCAAGTTCCTTGCTTTCTCTGAGTGCTTTCC
TTTCCTTTCCCTTTTCTTTTCTTTTTTGTTTTTCTTTTGTTTTGAGACGGAGTTTCACTCTTGTTGCCCAGCCTGGAGTGCAATAGCGCGGTCTCAGTTC
ACCACAACCTCTGCCTCCCGGGTTCAAGTGTAGCTAGGATTGCAGGCATGTGCCACCACGCCCAGCTAATTTTGTATTTTTAGTAGAGACGAGGTTTCTC
CATGTTGGTCAGACTGGTCTTGGACTCCCGACCTCAGGTGATCCGCCCGCCCTGGCCTCTCAGAGTGCTGGGATTACAGGCATGACCCACCCCATCCGGC
CCTCTGAGTCTTTCTTATCTGTAAAATGGGTATAATAATACCTATCTAATCGGTTTTAGTAATGGTGGAGATAATGCCTGAAAGTGCTAGTATAGAGGTT
TAATACCCAGCAAGGACTGTTATTAGAATGAATAGTAATATGACTACTGTCACATTTTGCAAATGTGTAAAGAAGAAAGAGGGCTAAGTGAATCAAAGGG
AGACAGCCCCACTCACCCTGTTCTGCCCCAGAGGACTGAGCGATCCCCACCATCTGGGAAGCTGCCTCACCAGGAGGTCCAGCTGGGGCTACAGGACTGG
CTACTTTGCTACAATGGCCCATCTTTCCTGAGCCCAGTGGAGGGTCCCAGGGGGGCAGAAGTCATTGATAGGGGCCAGTAGGGTTGTAGAGCCACTGTCT
GAACTTCTGTGGAGGTCTGGTGCAGGGGAGGTGTGAACAGATAGGAGGCTAGGTGAGGATGCAGCAGAGGAAGGGGGCAGGAGTGCCCCAGGAGGGGGCG
GTACCGAGGCAGGGATTCAGCTGGGTCTGAGAGGGAGGGAAGGCTGAGGGGGATGGCCCTTTGGAGTGGGCAGGGACATGACCACAGAAAGCCTGGGAAG
TGGAAACAGACAGGAGCCTGCTGGAGCTCTTGGAGCTTTGTGTGGGGCACTAGGGGAAGGAGGCAGGCACTCCACCCTGACCTGCCCCTACCTCTGGATG
AGGGTCTTCTCTGCCTGTTGGATGATGTGCTGCCCCTGCTCTTGGAGGAAGAGGCCTCCCAGCCACCCCCTCCTGCCAGTCGCCTTGCCCTGCTGACCCA
GACAGATCTGCTATCCCTACAGCATCCAGGAAGGCCACAGGGAGGGGGCCCAGGTGGCATGGGTTTCTGAGGCCTGGGATCTGCTCTCAGTCCCGCTCTC
GCCAACCCCCTTTGCCCCTCTGTGACAGTGTGTGTACATATGCGTGCATGTGTGTACCTGTGTGGTGTGGCTCACAAGGTCACCCCTGGGGGTGGGATAA
TAAGAGGTAAAGTGTGACCCCCTCTCTTCCGTACATTCATTTTTTCAAGCTTGTGAATATTCACATTGTTAATATAATCTTCTGCAGTCCCATGACTTCG
AATAGCACTTAGATGCCGATGACCCCCCCACCAAAGAAACCCCACTGTCTCCCACAGACTCCAGGTCTGTATCTCCAACTGCCTACTCAATACAACACGT
CCACCTGATACAATGAACTTAATGTGTCTAAACCCCAATTCCACATTTCCAGTCCTCCTACCGGCTCCTCCCCCAGTCTTCTCTACTTTACTATATGACA
ACTCCATTTTTCCCAATACTGGTTTTAAAAACCCTGGAGTAGTCCTTGACTCCAGTCTCTCTCACCTTTCAACCAATTCAGCAGCAAATACTGACAGCTC
TACCTTTGCTCATCAAAGCATATCCCCAAATCACCCTATTCCAGACTGCACACTGTCATCTCTCCCTTCAATTACAGCAGTAGCCTCCTAACTAGTTTTC
TTGATTCCACTCCTGCCCATCAGCAGTGAAATTACCCCAGAGCAGTTAAAATGATCTTTTAGGATGGGCACAGTGGCTCACGCCTGTAATACCAGCACTT
TGGGAGGTGGAGGCTGGCTGATCCCCTTAGGTTGGGAGTTCAAGACCATCCTCACCAACAGGGAGAAACCCCATCTCTACTAAAAATACAAAAATTAGCC
GGATGTGGTGGGACGTGTCTGTAATCCCAACTACTTGGGAGGCTGAGACAGGAGAACTGCTTGAACCCGGGAGGTGGAGGTTGCAGTGAGCCAGAATCGT
GCCACAGCACTCCAGCCTGGGCAAGAAGCGCGAAACTCCGTCTCAAAATAAAATAATCTTCTAAAAATGACAGGGCCAGGTGGGGTGGCACTTTTTTATA
ATCCGAGCACTTTGGGAGGCTGAGGTGGGCAGATCGCTTGACATCAGGGGTTTGAGACCAGCCTGGCCAACATGGTGAAACTCCGTCTCTACTAAAAATA
CTAAAAATTAGCTGGGCGTGGTGGCGGGTGCCTGTAATCCCAGCTACTCGGGAGGCTGATGCAGGAGAATCGCCTGAACCAGGCAGATGCAGGATGCAGT
GAGCCAAGATTAAGACACTGCACTCCAACCTAAGCAATACTTTGTCTCAAAAATAAAAAAAAGCCTGGGAAACAAAGTGAGACCCCGTCTCTACAAAAAA
GTCAAAAAATTAGCTGGGTATGGTGGCAGTGATGGCACACACCTGTAGTCCCGGCTACTTGGGAAGCTTTTTAATATTTTTTGCAGAGACCGGGTCTCAC
TCTGTTACCTGGCCTGGTCTTGAACTCCTGGGCTCCAACAATCCCCTTTCCTGGGCCTCCCAAAGTGCTGGGATTACAGGCATGAGCCACCGTGCCCAGC
CTCAAAGCATATTTTAAAGGATAGAAATAAACAGCCATATGAAGAGATACAGACAGGGCGGTCTGGAAGGGTCCAGAGCAGGAGCTTCTATCTCCATAGA
GTTGGGGTTACGTCACCCTCTGGGCACATTCTGTCAGCCTCCACACGTTCAGCCCTCAGAAGCTCCCGAACCCTGTCCTTTGGGCCTTTTATGGAGAACT
CCATTGGCTGTCCATGACTGAAGCATGGACAACTGTGATAATGTGATTGGGCAAAAAGGGTCTGATCTAAGCCCAGCAAGGCCAGTCCAGATTCTTTGGG
CCTTTGTGCAGCATTCCTTTCTCCAGGGTATGGGGCAAGGACCCACTCTGGAATGAGGATCCTACAACCCACAATCAGATTAGAGTCCTGCCTTGGGCAG
CTGAAAAGAGGACAGGAGAAGGTCAGAGAGACGAAAGGCTGTTTTTTGAGGCCTGAGGCACCCCAACATGACAACGTAAGACTGTAACCATGGTCATGTG
AGTTATGAGCTAGGAACCCTGGACGAAACCAGCACATATACAATCATCTCCCACCTCCCAACGCCTTTACTTTCACAGCCTCTGCAGCAAACTGCGGTCA
CTATAATCGCTCCTGTGGCACAGAGGCATACCCAGGGGAATCTGCCCAGGGGGCCACTCTGTGCCCACGTGGGAACCCACACCTGCTTGTAAAGCCTCCC
CTCCCTCTGACCAGCAACCAGGACAGTTTGTTGTTCCAAGCAGTGGGCTCATGTCTGTTTTGGCTCAGAACAGGGTGGGGAGAGCGGGCCAGGGACCCGC
AGGAAGGCTTATCCTTGAGATTGCGTGGGAGACACAACAAGGGGTGGGGGCCCGCAGGCGGGGCGGGGCGAAGCAGGTGATATCAAGCCCAGAGCCCCAG
CCTCTCCCCACAGTCTCACCATGGCCCGCACCGTGGTGCTCATCACCGGCTGTTCCTCGGGCATCGGCCTGCACTTGGCCGTACGTCTGGCTTCAGATCC
ATCCCAGAGCTTCAAAGTGTATGCCACGTTGAGGGACCTGAAAACACAGGGCCGGCTGTGGGAGGCGGCCCGGGCCCTGGCATGCCCTCCGGGATCCCTG
GAGACGTTGCAGCTGGACGTAAGGGACTCAAAATCCGTGGCCGCTGCCCGGGAACGCGTGACTGAGGGCCGCGTGGACGTGCTGGTGTGTAACGCAGGCC
TGGGCCTGCTGGGGCCGCTGGAGGCGCTGGGGGAGGACGCCGTGGCCTCTGTGCTGGACGTGAATGTAGTAGGGACTGTGCGGATGCTGCAGGCCTTCCT
GCCAGACATGAAGAGGCGCGGTTCGGGACGCGTGTTGGTGACCGGGAGCGTGGGAGGATTGATGGCTTGAGCCTGATCGAGTGCGGCCCAGTGCACACCG
CCTTCATGGAGAAGGTGTTGGGCAGCCCAGAGGAGGTGCTGGACCGCACGGACATCCACACCTTCCACCGCTTCTACCAATACCTCGCCCACAGCAAGCA
AGTCTTTCGCGAGGCGGCGCAGAACCCTGAGGAGGTGGCGGAGGTGAGCGCCGGGCTGGACTCCAGGAGTGGGGGCGGTGCGTCCTCCGGCGCGCAGCGG
TGGCCACAGCTCTCCTCCCGCCGCCGCAGGTCTTCCTCACCGCTTTGCGCGCCCCGAAGCCGACCCTGCGCTACTTCACCACCGAGCGCTTCCTGCCCCT
GCTGCGGATGCGCCTGGACGACCCCAGCGGCTCCAACTACGTCACCGCCATGCACCGGGAAGTGTTCGGCGACGTTCCGGCAAAGGCCGAGGCTGGGGCC
GAGGCTGGGGGCGGGGCCGGGCCTGGGGCAGAGGACGAGGCCGGGCGCGGTGCGGTGGGGGACCCTGAGCTCGGCGATCCTCCGGCCGCCCCGCAGTAAA
GGCTTCCTCAGCCGCTGTCTCCCGCGCCCTTCTTTGTCCCCTGGGTCTGTGTGGTCCCTGGGGATGGGGCGGCGGTAGCAGCTGTGGGTGGCTAATTAAG
ATAGATCGCGTTAGCCAGTTTTACCAGCGCAGCTAGGCGCGATGGCTGTCGCCTGTAATGCCAGCGCTTTGGGAGGCGGAGGCAGGAGGATCGCTCAAGC
CCCGGAGTTGGAGACCAGCCAGAGCAACACAGTGAGACCCCCATCTCTACAAAAATAAAGAAAATTT
  • HSD17B1.F3 (forward primer)
  • HSD17B1.R3 (reverse primer)
  • Intron retention

Frame 0

S*VGLGLG*SQVVTCTPLAMRPQASSLLSLSAF
LSFPFSFLFCFSFVLRRSFTLVAQPGVQ*RGLSS
PQPLPPGFKCS*DCRHVPPRPANFVFLVETRFL
HVGQTGLGLPTSGDPPALASQSAGITGMTHPIR
PSESFLSVKWV**YLSNRF**WWR*CLKVLV*RF
NTQQGLLLE*IVI*LLSHFANV*RRKRAK*IKG
RQPHSPCSAPED*AIPTIWEAASPGGPAGATGL
ATLLQWPIFPEPSGGSQGGRSH**GPVGL*SHCL
NFCGGLVQGRCEQIGG*VRMQQRKGAGVPQEGA
VPRQGFSWV*EGGKAEGDGPLEWAGT*PQKAWE
VETDRSLLELLELCVGH*GKEAGTPP*PAPTSG*
GSSLPVG*CAAPALGGRGLPATPSCQSPCPADP
DRSAIPTASRKATGRGPRWHGFLRPGICSQSRS
RQPPLPLCDSVCTYACMCVPVWCGSQGHPWGWDN
KR*SVTPSLPYIHFFKLVNIHIVNIIFCSPMTS
NST*MPMTPPPKKPHCLPQTPGLYLQLPTQYNT
ST*YNELNVSKPQFHISSPPTGSSPSLLYFTI*Q
LHFSQYWF*KPWSSP*LQSLSPFNQFSSKY*QL
YLCSSKHIPKSPYSRLHTVISPFNYSSSLLTSF
LDSTPAHQQ*NYPRAVKMIF*DGHSGSRL*YQHF
GRWRLADPLRLGVQDHPHQQGETPSLLKIQKLA
GCGGTCL*SQLLGRLRQENCLNPGGGGCSEPES
CHSTPAWARSAKLRLKIK*SSKNDRARWGGTFL*
SEHFGRLRWADRLTSGV*DQPGQHGETPSLLKI
LKISWAWWRVPVIPATREADAGESPEPGRCRMQ
*AKIKTLHSNLSNTLSQK*KKAWETK*DPVSTKK
SKN*LGMVAVMAHTCSPGYLGSFLIFFAETGSH
SVTWPGLELLGSNNPLSWASQSAGITGMSHRAQ
PQSIF*RIEINSHMKRYRQGGLEGSRAGASISIE
LGLRHPLGTFCQPPHVQPSEAPEPCPLGLLWRT
PLAVHD*SMDNCDNVIGQKGSDLSPARPVQILW
AFVQHSFLQGMGQGPTLE*GSYNPQSD*SPALGS
*KEDRRRSERRKAVF*GLRHPNMTT*DCNHGHV
SYELGTLDETSTYTIISHLPTPLLSQPLQQTAV
TIIAPVAQRHTQGNLPRGPLCAHVGTHTCL*SLP
SL*PATRTVCCSKQWAHVCFGSEQGGESGPGTR
RKAYP*DCVGDTTRGGGPQAGRGEAGDIKPRAP
ASPHSLTMARTVVLITGCSSGIGLHLAVRLASDP
SQSFKVYATLRDLKTQGRLWEAARALACPPGSL
ETLQLDVRDSKSVAAARERVTEGRVDVLVCNAG
LGLLGPLEALGEDAVASVLDVNVVGTVRMLQAFL
PDMKRRGSGRVLVTGSVGGLMA*A*SSAAQCTP
PSWRRCWAAQRRCWTARTSTPSTASTNTSPTAS
KSFARRRRTLRRWRR*APGWTPGVGAVRPPARSG
GHSSPPAAAGLPHRFARPEADPALLHHRALPAP
AADAPGRPQRLQLRHRHAPGSVRRRSGKGRGWG
RGWGRGRAWGRGRGRARCGGGP*ARRSSGRPAVK
ASSAAVSRALLCPLGLCGPWGWGGGSSCGWLIK
IDRVSQFYQRS*ARWLSPVMPALWEAEAGGSLK
PRSWRPARATQ*DPHLYKNKEN

Frame 1

VRWDLGWGRVRL*PALH*P*DLRQVPCFL*VLS
FPFPFLFFFVFLLF*DGVSLLLPSLECNSAVSV
HHNLCLPGSSVARIAGMCHHAQLILYF**RRGFS
MLVRLVLDSRPQVIRPPWPLRVLGLQA*PTPSG
PLSLSYL*NGYNNTYLIGFSNGGDNA*KC*YRG
LIPSKDCY*NE**YDYCHILQMCKEERGLSESKG
DSPTHPVLPQRTERSPPSGKLPHQEVQLGLQDW
LLCYNGPSFLSPVEGPRGAEVIDRGQ*GCRATV
*TSVEVWCRGGVNR*EAR*GCSRGRGQECPRRGR
YRGRDSAGSEREGRLRGMALWSGQGHDHRKPGK
WKQTGACWSSWSFVWGTRGRRQALHPDLPLPLD
EGLLCLLDDVLPLLLEEEASQPPPPASRLALLTQ
TDLLSLQHPGRPQGGGPGGMGF*GLGSALSPAL
ANPLCPSVTVCVHMRACVYLCGVAHKVTPGGGI
IRGKV*PPLFRTFIFSSL*IFTLLI*SSAVP*LR
IALRCR*PPHQRNPTVSHRLQVCISNCLLNTTR
PPDTMNLMCLNPNSTFPVLLPAPPPVFSTLLYD
NSIFPNTGFKNPGVVLDSSLSHLSTNSAANTDSS
TFAHQSISPNHPIPDCTLSSLPSITAVAS*LVF
LIPLLPISSEITPEQLK*SFRMGTVAHACNTST
LGGGGWLIPLGWEFKTILTNREKPHLY*KYKN*P
DVVGRVCNPNYLGG*DRRTA*TREVEVAVSQNR
ATALQPGQEARNSVSK*NNLLKMTGPGGVALFY
NPSTLGG*GGQIA*HQGFETSLANMVKLRLY*KY
*KLAGRGGGCL*SQLLGRLMQENRLNQADAGCS
EPRLRHCTPT*AILCLKNKKKPGKQSETPSLQK
SQKISWVWWQ*WHTPVVPATWEAF*YFLQRPGLT
LLPGLVLNSWAPTIPFPGPPKVLGLQA*ATVPS
LKAYFKG*K*TAI*RDTDRAVWKGPEQELLSP*
SWGYVTLWAHSVSLHTFSPQKLPNPVLWAFYGEL
HWLSMTEAWTTVIM*LGKKGLI*AQQGQSRFFG
PLCSIPFSRVWGKDPLWNEDPTTHNQIRVLPWA
AEKRTGEGQRDERLFFEA*GTPT*QRKTVTMVM*
VMS*EPWTKPAHIQSSPTSQRLYFHSLCSKLRS
L*SLLWHRGIPRGICPGGHSVPTWEPTPACKAS
PPSDQQPGQFVVPSSGLMSVLAQNRVGRAGQGPA
GRLILEIAWETQQGVGARRRGGAKQVISSPEPQ
PLPTVSPWPAPWCSSPAVPRASACTWPYVWLQI
HPRASKCMPR*GT*KHRAGCGRRPGPWHALRDPW
RRCSWT*GTQNPWPLPGNA*LRAAWTCWCVTQA
WACWGRWRRWGRTPWPLCWT*M**GLCGCCRPS
CQT*RGAVRDACW*PGAWED*WLEPDRVRPSAHR
LHGEGVGQPRGGAGPHGHPHLPPLLPIPRPQQA
SLSRGGAEP*GGGGGERRAGLQEWGRCVLRRAA
VATALLPPPQVFLTALRAPKPTLRYFTTERFLPL
LRMRLDDPSGSNYVTAMHREVFGDVPAKAEAGA
EAGGGAGPGAEDEAGRGAVGDPELGDPPAAPQ*
RLPQPLSPAPFFVPWVCVVPGDGAAVAAVGG*LR
*IALASFTSAARRDGCRL*CQRFGRRRQEDRSS
PGVGDQPEQHSETPISTKIKKI

Frame 2

LGGTWVGVESGCDLHSISHETSGKFLAFSECFP
FLSLFFSFLFFFCFETEFHSCCPAWSAIARSQF
TTTSASRVQV*LGLQACATTPS*FCIFSRDEVS
PCWSDWSWTPDLR*SARPGLSECWDYRHDPPHPA
L*VFLICKMGIIIPI*SVLVMVEIMPESASIEV
*YPARTVIRMNSNMTTVTFCKCVKKKEG*VNQR
ETAPLTLFCPRGLSDPHHLGSCLTRRSSWGYRTG
YFATMAHLS*AQWRVPGGQKSLIGASRVVEPLS
ELLWRSGAGEV*TDRRLGEDAAEEGGRSAPGGG
GTEAGIQLGLRGREG*GGWPFGVGRDMTTESLGS
GNRQEPAGALGALCGALGEGGRHSTLTCPYLWM
RVFSACWMMCCPCSWRKRPPSHPLLPVALPC*P
RQICYPYSIQEGHREGAQVAWVSEAWDLLSVPLS
PTPFAPL*QCVYICVHVCTCVVWLTRSPLGVG*
*EVKCDPLSSVHSFFQACEYSHC*YNLLQSHDF
E*HLDADDPPTKETPLSPTDSRSVSPTAYSIQHV
HLIQ*T*CV*TPIPHFQSSYRLLPQSSLLYYMT
TPFFPILVLKTLE*SLTPVSLTFQPIQQQILTA
LPLLIKAYPQITLFQTAHCHLSLQLQQ*PPN*FS
*FHSCPSAVKLPQSS*NDLLGWAQWLTPVIPAL
WEVEAG*SP*VGSSRPSSPTGRNPISTKNTKIS
RMWWDVSVIPTTWEAETGELLEPGRWRLQ*ARIV
PQHSSLGKKRETPSQNKIIF*K*QGQVGWHFFI
IRALWEAEVGRSLDIRGLRPAWPTW*NSVSTKN
TKN*LGVVAGACNPSYSGG*CRRIA*TRQMQDAV
SQD*DTALQPKQYFVSKIKKSLGNKVRPRLYKK
VKKLAGYGGSDGTHL*SRLLGKLFNIFCRDRVS
LCYLAWS*TPGLQQSPFLGLPKCWDYRHEPPCPA
SKHILKDRNKQPYEEIQTGRSGRVQSRSFYLHR
VGVTSPSGHILSASTRSALRSSRTLSFGPFMEN
SIGCP*LKHGQL**CDWAKRV*SKPSKASPDSLG
LCAAFLSPGYGARTHSGMRILQPTIRLESCLGQ
LKRGQEKVRETKGCFLRPEAPQHDNVRL*PWSC
EL*ARNPGRNQHIYNHLPPPNAFTFTASAANCGH
YNRSCGTEAYPGESAQGATLCPRGNPHLLVKPP
LPLTSNQDSLLFQAVGSCLFWLRTGWGERARDP
QEGLSLRLRGRHNKGWGPAGGAGRSR*YQAQSPS
LSPQSHHGPHRGAHHRLFLGHRPALGRTSGFRS
IPELQSVCHVEGPENTGPAVGGGPGPGMPSGIP
GDVAAGRKGLKIRGRCPGTRD*GPRGRAGV*RRP
GPAGAAGGAGGGRRGLCAGRECSRDCADAAGLP
ARHEEARFGTRVGDRERGRIDGLSLIECGPVHT
AFMEKVLGSPEEVLDRTDIHTFHRFYQYLAHSKQ
VFREAAQNPEEVAEVSAGLDSRSGGGASSGAQR
WPQLSSRRRRSSSPLCAPRSRPCATSPPSASCP
CCGCAWTTPAAPTTSPPCTGKCSATFRQRPRLGP
RLGAGPGLGQRTRPGAVRWGTLSSAILRPPRSK
GFLSRCLPRPSLSPGSVWSLGMGRR*QLWVAN*
DRSR*PVLPAQLGAMAVACNASALGGGGRRIAQA
PELETSQSNTVRPPSLQK*RKF

Sequence HSD17B1.shed1.aAug05

AGGACCCACTCTGGAATGAGGATCCTACAACCCACAATCAGATTAGAGTCCTGCCTTGGGCAGCTGAAAAGAGGACAGGAGAAGGTCAGAGAGACGAAAG
GCTGTTTTTTGAGGCCTGAGGCACCCCAACATGACAACGTAAGACTGTAACCATGGTCATGTGAGTTATGAGCTAGGAACCCTGGACGAAACCAGCACAT
ATACAATCATCTCCCACCTCCCAACGCCTTTACTTTCACAGCCTCTGCAGCAAACTGCGGTCACTATAATCGCTCCTGTGGCACAGAGGCATACCCAGGG
GAATCTGCCCAGGGGGCCACTCTGTGCCCACGTGGGAACCCACACCTGCTTGTAAAGCCTCCCCTCCCTCTGACCAGCAACCAGGACAGTTTGTTGTTCC
AAGCAGTGGGCTCATGTCTGTTTTGGCTCAGAACAGGGTGGGGAGAGCGGGCCAGGGACCCGCAGGAAGGCTTATCCTTGAGATTGCGTGGGAGACACAA
CAAGGGGTGGGGGCCCGCAGGCGGGGCGGGGCGAAGCAGGTGATATCAAGCCCAGAGCCCCAGCCTCTCCCCACAGTCTCACCATGGCCCGCACCGTGGT
GCTCATCACCGGCTGTTCCTCGGGCATCGGCCTGCACTTGGCCGTACGTCTGGCTTCAGATCCATCCCAGAGCTTCAAAGGTATAGATAGGCAGGGACAG
GGAGGGAGAGAAGGGAGGAGCCCTTGGAGGCCAGAAGGGAAGTCAGATCTTCCTCCTCTCCCAAAACCTCCAGTGTATGCCACGTTGAGGGACCTGAAAA
CACAGGGCCGGCTGTGGGAGGCGGCCCGGGCCCTGGCATGCCCTCCGGGATCCCTGGAGACGTTGCAGCTGGACGTAAGGGACTCAAAATCCGTGGCCGC
TGCCCGGGAACGCGTGACTGAGGGCCGCGTGGACGTGCTGGGTGAGCCTCCTGGAAGCATATGGGCTCCTAGGAGCCTTCTCCGCCCTGCGTTGAAACCA
ACATGTTCCCAGGCCCAGGGAGCACGAGGGGACAGGCCGTGCTGAGGGTGATGCTGAGGCGGGCTGGTCGGGCCTCTTGTCTCCGCAGTGTGTAACGCAG
GCCTGGGCCTGCTGGGGCCGCTGGAGGCGCTGGGGGAGGACGCCGTGGCCTCTGTGCTGGACGTGAATGTAGTAGGGACTGTGCGGATGCTGCAGGCCTT
CCTGCCAGACATGAAGAGGCGCGGTTCGGGACGCGTGTTGGTGACCGGGAGCGTGGGAGGATTGATGGGTGAGTGGTAGGGAGTGGCCTCGGCAGCTCCA
GATTCTTTGTGTGCGGAGCTGAGCCTTGAAGGCAGGTTCCGCGGGGGGGGTGGAGTGGGGTGCCGTCAGCTTGGAGGGGCACCGTCTGCCCGGGGATGAC
CCCCTGGCCGCTGCGCCTCAGGAACCTCGTCTCCCCACCTAAGGGCTGCCTTTCAATGACGTTTATTGCGCCAGCAAGTTCGCGCTCGAAGGCTTATGCG
AGAGTCTGGCGGTTCTGCTGCTGCCCTTTGGGGTCCAGTGAGTCAACACCCCCGTTCCCCGAACCCTCTTAACTCTGACCTAGAGACGCCGAGCACCCTG
TCCTGCGGGAGCCGCTCTGGGGCGATCTCCCTGGCCCTCTCTGCCCGGCTCACATTAGCTGTGTGCCAGGCACTTGGGCTGGGCGCATGGCACGCATTGT
GCCACCTGCTGACCTAGCTGCTGAAGTGTTGGTATTGTTATGGGGAAGCTCCAGCCCAGAGAGGTTAGGTGACTGGCCCAAGGTCACACAGCGGCCAGGG
ACCCCGCTAGATTCGAATCCTGACACCAGGGCTCCCTTGTAGCCTCAGATGGATTTGGGAGGGCTGCTCCGGCAGGAACCCGCGTTTCAAATGTTCTGGT
TATCCCCAGCGCCCTTTCCGCCTCACTTCCCAGCGCAGCGGTGCTGCTCGCGGTCGGGGGCCGGGACGTGGTTGGGGCTGGGACTGGGGTTGGGGCTGGG
ACTGGGGCCTGGCTGGCGTCCGCCCCCTCCCACTCGTTGCTCTCCGGCCAGCAG
CTTGAGCCTGATCGAGTGCGGCCCAGTGCACACCGCCTTCATGGAG
AAGGTGTTGGGCAGCCCAGAGGAGGTGCTGGACCGCACGGACATCCACACCTTCCACCGCTTCTACCAATACCTCGCCCACAGCAAGCAAGTCTTTCGCG
AGGCGGCGCAGAACCCTGAGGAGGTGGCGGAGGTGAGCGCCGGGCTGGACTCCAGGAGTGGGGGCGGTGCGTCCTCCGGCGCGCAGCGGTGGCCACAGCT
CTCCTCCCGCCGCCGCAGGTCTTCCTCACCGCTTTGCGCGCCCCGAAGCCGACCCTGCGCTACTTCACCACCGAGCGCTTCCTGCCCCTGCTGCGGATGC
GCCTGGACGACCCCAGCGGCTCCAACTACGTCACCGCCATGCACCGGGAAGTGTTCGGCGACGTTCCGGCAAAGGCCGAGGCTGGGGCCGAGGCTGGGGG
CGGGGCCGGGCCTGGGGCAGAGGACGAGGCCGGGCGCGGTGCGGTGGGGGACCCTGAGCTCGGCGATCCTCCGGCCGCCCCGCAGTAAAGGCTTCCTCAG
CCGCTGTCTCCCGCGCCCTTCTTTGTCCCCTGGGTCTGTGTGGTCCCTGGGGATGGGGCGGCGGTAGCAGCTGTGGGTGGCTAATTAAGATAGATCGCGT
TAGCCAGTTTTACCAGCGCAGCTAGGCGCGATGGCTGTCGCCTGTAATGCCAGCGCTTTGGGAGGCGGAGGCAGGAGGATCGCTCAAGCCCCGGAGTTGG
AGACCAGCCAGAGCAACACAGTGAGACCCCCATCTCTACAAAAATAAAGAAAATTT
  • HSD17B1.F3 (forward primer)
  • HSD17B1.R3 (reverse primer)
  • Intron retention

Frame 0

RTHSGMRILQPTIRLESCLGQLKRGQEKVRETK
GCFLRPEAPQHDNVRL*PWSCEL*ARNPGRNQHI
YNHLPPPNAFTFTASAANCGHYNRSCGTEAYPG
ESAQGATLCPRGNPHLLVKPPLPLTSNQDSLLF
QAVGSCLFWLRTGWGERARDPQEGLSLRLRGRHN
KGWGPAGGAGRSR*YQAQSPSLSPQSHHGPHRG
AHHRLFLGHRPALGRTSGFRSIPELQRYR*AGT
GRERREEPLEARREVRSSSSPKTSSVCHVEGPEN
TGPAVGGGPGPGMPSGIPGDVAAGRKGLKIRGR
CPGTRD*GPRGRAG*ASWKHMGS*EPSPPCVET
NMFPGPGSTRGQAVLRVMLRRAGRASCLRSV*RR
PGPAGAAGGAGGGRRGLCAGRECSRDCADAAGL
PARHEEARFGTRVGDRERGRIDG*VVGSGLGSS
RFFVCGAEP*RQVPRGGWSGVPSAWRGTVCPGMT
PWPLRLRNLVSPPKGCLSMTFIAPASSRSKAYA
RVWRFCCCPLGSSESTPPFPEPS*L*PRDAEHP
VLREPLWGDLPGPLCPAHISCVPGTWAGRMARIV
PPADLAAEVLVLLWGSSSPERLGDWPKVTQRPG
TPLDSNPDTRAPL*PQMDLGGLLRQEPAFQMFW
LSPAPFPPHFPAQRCCSRSGAGTWLGLGLGLGLG
LGPGWRPPPPTRCSPASS
LSLIECGPVHTAFME
KVLGSPEEVLDRTDIHTFHRFYQYLAHSKQVFR
EAAQNPEEVAEVSAGLDSRSGGGASSGAQRWPQL
SSRRRRSSSPLCAPRSRPCATSPPSASCPCCGC
AWTTPAAPTTSPPCTGKCSATFRQRPRLGPRLG
AGPGLGQRTRPGAVRWGTLSSAILRPPRSKGFLS
RCLPRPSLSPGSVWSLGMGRR*QLWVAN*DRSR
*PVLPAQLGAMAVACNASALGGGGRRIAQAPEL
ETSQSNTVRPPSLQK*RKF

Frame 1

GPTLE*GSYNPQSD*SPALGS*KEDRRRSERRK
AVF*GLRHPNMTT*DCNHGHVSYELGTLDETST
YTIISHLPTPLLSQPLQQTAVTIIAPVAQRHTQG
NLPRGPLCAHVGTHTCL*SLPSL*PATRTVCCS
KQWAHVCFGSEQGGESGPGTRRKAYP*DCVGDT
TRGGGPQAGRGEAGDIKPRAPASPHSLTMARTVV
LITGCSSGIGLHLAVRLASDPSQSFKGIDRQGQ
GGREGRSPWRPEGKSDLPPLPKPPVYATLRDLK
TQGRLWEAARALACPPGSLETLQLDVRDSKSVAA
ARERVTEGRVDVLGEPPGSIWAPRSLLRPALKP
TCSQAQGARGDRPC*G*C*GGLVGPLVSAVCNA
GLGLLGPLEALGEDAVASVLDVNVVGTVRMLQAF
LPDMKRRGSGRVLVTGSVGGLMGEW*GVASAAP
DSLCAELSLEGRFRGGGGVGCRQLGGAPSARG*
PPGRCASGTSSPHLRAAFQ*RLLRQQVRARRLMR
ESGGSAAALWGPVSQHPRSPNPLNSDLETPSTL
SCGSRSGAISLALSARLTLAVCQALGLGAWHAL
CHLLT*LLKCWYCYGEAPAQRG*VTGPRSHSGQG
PR*IRILTPGLPCSLRWIWEGCSGRNPRFKCSG
YPQRPFRLTSQRSGAARGRGPGRGWGWDWGWGW
DWGLAGVRPLPLVALRPA
A*A*SSAAQCTPPSWR
RCWAAQRRCWTARTSTPSTASTNTSPTASKSFA
RRRRTLRRWRR*APGWTPGVGAVRPPARSGGHS
SPPAAAGLPHRFARPEADPALLHHRALPAPAADA
PGRPQRLQLRHRHAPGSVRRRSGKGRGWGRGWG
RGRAWGRGRGRARCGGGP*ARRSSGRPAVKASS
AAVSRALLCPLGLCGPWGWGGGSSCGWLIKIDRV
SQFYQRS*ARWLSPVMPALWEAEAGGSLKPRSW
RPARATQ*DPHLYKNKEN

Frame 2

DPLWNEDPTTHNQIRVLPWAAEKRTGEGQRDER
LFFEA*GTPT*QRKTVTMVM*VMS*EPWTKPAH
IQSSPTSQRLYFHSLCSKLRSL*SLLWHRGIPR
GICPGGHSVPTWEPTPACKASPPSDQQPGQFVVP
SSGLMSVLAQNRVGRAGQGPAGRLILEIAWETQ
QGVGARRRGGAKQVISSPEPQPLPTVSPWPAPW
CSSPAVPRASACTWPYVWLQIHPRASKV*IGRDR
EGEKGGALGGQKGSQIFLLSQNLQCMPR*GT*K
HRAGCGRRPGPWHALRDPWRRCSWT*GTQNPWP
LPGNA*LRAAWTCWVSLLEAYGLLGAFSALR*NQ
HVPRPREHEGTGRAEGDAEAGWSGLLSPQCVTQ
AWACWGRWRRWGRTPWPLCWT*M**GLCGCCRP
SCQT*RGAVRDACW*PGAWED*WVSGREWPRQLQ
ILCVRS*ALKAGSAGGVEWGAVSLEGHRLPGDD
PLAAAPQEPRLPT*GLPFNDVYCASKFALEGLC
ESLAVLLLPFGVQ*VNTPVPRTLLTLT*RRRAPC
PAGAALGRSPWPSLPGSH*LCARHLGWAHGTHC
ATC*PSC*SVGIVMGKLQPREVR*LAQGHTAAR
DPARFES*HQGSLVASDGFGRAAPAGTRVSNVLV
IPSALSASLPSAAVLLAVGGRDVVGAGTGVGAG
TGAWLASAPSHSLLSGQQ
LEPDRVRPSAHRLHG
EGVGQPRGGAGPHGHPHLPPLLPIPRPQQASLSR
GGAEP*GGGGGERRAGLQEWGRCVLRRAAVATA
LLPPPQVFLTALRAPKPTLRYFTTERFLPLLRM
RLDDPSGSNYVTAMHREVFGDVPAKAEAGAEAGG
GAGPGAEDEAGRGAVGDPELGDPPAAPQ*RLPQ
PLSPAPFFVPWVCVVPGDGAAVAAVGG*LR*IA
LASFTSAARRDGCRL*CQRFGRRRQEDRSSPGVG
DQPEQHSETPISTKIKKI

Sequence HSD17B1.gAug05

AGTTAGGTGGGACTTGGGTTGGGGTAGAGTCAGGTTGTGACCTGCACTCCATTAGCCATGAGACCTCAGGCAAGTTCCTTGCTTTCTCTGAGTGCTTTCC
TTTCCTTTCCCTTTTCTTTTCTTTTTTGTTTTTCTTTTGTTTTGAGACGGAGTTTCACTCTTGTTGCCCAGCCTGGAGTGCAATAGCGCGGTCTCAGTTC
ACCACAACCTCTGCCTCCCGGGTTCAAGTGTAGCTAGGATTGCAGGCATGTGCCACCACGCCCAGCTAATTTTGTATTTTTAGTAGAGACGAGGTTTCTC
CATGTTGGTCAGACTGGTCTTGGACTCCCGACCTCAGGTGATCCGCCCGCCCTGGCCTCTCAGAGTGCTGGGATTACAGGCATGACCCACCCCATCCGGC
CCTCTGAGTCTTTCTTATCTGTAAAATGGGTATAATAATACCTATCTAATCGGTTTTAGTAATGGTGGAGATAATGCCTGAAAGTGCTAGTATAGAGGTT
TAATACCCAGCAAGGACTGTTATTAGAATGAATAGTAATATGACTACTGTCACATTTTGCAAATGTGTAAAGAAGAAAGAGGGCTAAGTGAATCAAAGGG
AGACAGCCCCACTCACCCTGTTCTGCCCCAGAGGACTGAGCGATCCCCACCATCTGGGAAGCTGCCTCACCAGGAGGTCCAGCTGGGGCTACAGGACTGG
CTACTTTGCTACAATGGCCCATCTTTCCTGAGCCCAGTGGAGGGTCCCAGGGGGGCAGAAGTCATTGATAGGGGCCAGTAGGGTTGTAGAGCCACTGTCT
GAACTTCTGTGGAGGTCTGGTGCAGGGGAGGTGTGAACAGATAGGAGGCTAGGTGAGGATGCAGCAGAGGAAGGGGGCAGGAGTGCCCCAGGAGGGGGCG
GTACCGAGGCAGGGATTCAGCTGGGTCTGAGAGGGAGGGAAGGCTGAGGGGGATGGCCCTTTGGAGTGGGCAGGGACATGACCACAGAAAGCCTGGGAAG
TGGAAACAGACAGGAGCCTGCTGGAGCTCTTGGAGCTTTGTGTGGGGCACTAGGGGAAGGAGGCAGGCACTCCACCCTGACCTGCCCCTACCTCTGGATG
AGGGTCTTCTCTGCCTGTTGGATGATGTGCTGCCCCTGCTCTTGGAGGAAGAGGCCTCCCAGCCACCCCCTCCTGCCAGTCGCCTTGCCCTGCTGACCCA
GACAGATCTGCTATCCCTACAGCATCCAGGAAGGCCACAGGGAGGGGGCCCAGGTGGCATGGGTTTCTGAGGCCTGGGATCTGCTCTCAGTCCCGCTCTC
GCCAACCCCCTTTGCCCCTCTGTGACAGTGTGTGTACATATGCGTGCATGTGTGTACCTGTGTGGTGTGGCTCACAAGGTCACCCCTGGGGGTGGGATAA
TAAGAGGTAAAGTGTGACCCCCTCTCTTCCGTACATTCATTTTTTCAAGCTTGTGAATATTCACATTGTTAATATAATCTTCTGCAGTCCCATGACTTCG
AATAGCACTTAGATGCCGATGACCCCCCCACCAAAGAAACCCCACTGTCTCCCACAGACTCCAGGTCTGTATCTCCAACTGCCTACTCAATACAACACGT
CCACCTGATACAATGAACTTAATGTGTCTAAACCCCAATTCCACATTTCCAGTCCTCCTACCGGCTCCTCCCCCAGTCTTCTCTACTTTACTATATGACA
ACTCCATTTTTCCCAATACTGGTTTTAAAAACCCTGGAGTAGTCCTTGACTCCAGTCTCTCTCACCTTTCAACCAATTCAGCAGCAAATACTGACAGCTC
TACCTTTGCTCATCAAAGCATATCCCCAAATCACCCTATTCCAGACTGCACACTGTCATCTCTCCCTTCAATTACAGCAGTAGCCTCCTAACTAGTTTTC
TTGATTCCACTCCTGCCCATCAGCAGTGAAATTACCCCAGAGCAGTTAAAATGATCTTTTAGGATGGGCACAGTGGCTCACGCCTGTAATACCAGCACTT
TGGGAGGTGGAGGCTGGCTGATCCCCTTAGGTTGGGAGTTCAAGACCATCCTCACCAACAGGGAGAAACCCCATCTCTACTAAAAATACAAAAATTAGCC
GGATGTGGTGGGACGTGTCTGTAATCCCAACTACTTGGGAGGCTGAGACAGGAGAACTGCTTGAACCCGGGAGGTGGAGGTTGCAGTGAGCCAGAATCGT
GCCACAGCACTCCAGCCTGGGCAAGAAGCGCGAAACTCCGTCTCAAAATAAAATAATCTTCTAAAAATGACAGGGCCAGGTGGGGTGGCACTTTTTTATA
ATCCGAGCACTTTGGGAGGCTGAGGTGGGCAGATCGCTTGACATCAGGGGTTTGAGACCAGCCTGGCCAACATGGTGAAACTCCGTCTCTACTAAAAATA
CTAAAAATTAGCTGGGCGTGGTGGCGGGTGCCTGTAATCCCAGCTACTCGGGAGGCTGATGCAGGAGAATCGCCTGAACCAGGCAGATGCAGGATGCAGT
GAGCCAAGATTAAGACACTGCACTCCAACCTAAGCAATACTTTGTCTCAAAAATAAAAAAAAGCCTGGGAAACAAAGTGAGACCCCGTCTCTACAAAAAA
GTCAAAAAATTAGCTGGGTATGGTGGCAGTGATGGCACACACCTGTAGTCCCGGCTACTTGGGAAGCTTTTTAATATTTTTTGCAGAGACCGGGTCTCAC
TCTGTTACCTGGCCTGGTCTTGAACTCCTGGGCTCCAACAATCCCCTTTCCTGGGCCTCCCAAAGTGCTGGGATTACAGGCATGAGCCACCGTGCCCAGC
CTCAAAGCATATTTTAAAGGATAGAAATAAACAGCCATATGAAGAGATACAGACAGGGCGGTCTGGAAGGGTCCAGAGCAGGAGCTTCTATCTCCATAGA
GTTGGGGTTACGTCACCCTCTGGGCACATTCTGTCAGCCTCCACACGTTCAGCCCTCAGAAGCTCCCGAACCCTGTCCTTTGGGCCTTTTATGGAGAACT
CCATTGGCTGTCCATGACTGAAGCATGGACAACTGTGATAATGTGATTGGGCAAAAAGGGTCTGATCTAAGCCCAGCAAGGCCAGTCCAGATTCTTTGGG
CCTTTGTGCAGCATTCCTTTCTCCAGGGTATGGGGCAAGGACCCACTCTGGAATGAGGATCCTACAACCCACAATCAGATTAGAGTCCTGCCTTGGGCAG
CTGAAAAGAGGACAGGAGAAGGTCAGAGAGACGAAAGGCTGTTTTTTGAGGCCTGAGGCACCCCAACATGACAACGTAAGACTGTAACCATGGTCATGTG
AGTTATGAGCTAGGAACCCTGGACGAAACCAGCACATATACAATCATCTCCCACCTCCCAACGCCTTTACTTTCACAGCCTCTGCAGCAAACTGCGGTCA
CTATAATCGCTCCTGTGGCACAGAGGCATACCCAGGGGAATCTGCCCAGGGGGCCACTCTGTGCCCACGTGGGAACCCACACCTGCTTGTAAAGCCTCCC
CTCCCTCTGACCAGCAACCAGGACAGTTTGTTGTTCCAAGCAGTGGGCTCATGTCTGTTTTGGCTCAGAACAGGGTGGGGAGAGCGGGCCAGGGACCCGC
AGGAAGGCTTATCCTTGAGATTGCGTGGGAGACACAACAAGGGGTGGGGGCCCGCAGGCGGGGCGGGGCGAAGCAGGTGATATCAAGCCCAGAGCCCCAG
CCTCTCCCCACAGTCTCACCATGGCCCGCACCGTGGTGCTCATCACCGGCTGTTCCTCGGGCATCGGCCTGCACTTGGCCGTACGTCTGGCTTCAGATCC
ATCCCAGAGCTTCAAAGTGTATGCCACGTTGAGGGACCTGAAAACACAGGGCCGGCTGTGGGAGGCGGCCCGGGCCCTGGCATGCCCTCCGGGATCCCTG
GAGACGTTGCAGCTGGACGTAAGGGACTCAAAATCCGTGGCCGCTGCCCGGGAACGCGTGACTGAGGGCCGCGTGGACGTGCTGGGTGAGCCTCCTGGAA
GCATATGGGCTCCTAGGAGCCTTCTCCGCCCTGCGTTGAAACCAACATGTTCCCAGGCCCAGGGAGCACGAGGGGACAGGCCGTGCTGAGGGTGATGCTG
AGGCGGGCTGGTCGGGCCTCTTGTCTCCGCAGTGTGTAACGCAGGCCTGGGCCTGCTGGGGCCGCTGGAGGCGCTGGGGGAGGACGCCGTGGCCTCTGTG
CTGGACGTGAATGTAGTAGG
GACTGTGCGGATGCTGCAGGCCTTCCTGCCAGACATGAAGAGGCGCGGTTCGGGACGCGTGTTGGTGACCGGGAGCGTGG
GAGGATTGATGGGTGAGTGGTAGGGAGTGGCCTCGGCAGCTCCAGATTCTTTGTGTGCGGAGCTGAGCCTTGAAGGCAGGTTCCGCGGGGGGGGTGGAGT
GGGGTGCCGTCAGCTTGGAGGGGCACCGTCTGCCCGGGGATGACCCCCTGGCCGCTGCGCCTCAGGAACCTCGTCTCCCCACCTAAGGGCTGCCTTTCAA
TGACGTTTATTGCGCCAGCAAGTTCGCGCTCGAAGGCTTATGCGAGAGTCTGGCGGTTCTGCTGCTGCCCTTTGGGGTCCAGTGAGTCAACACCCCCGTT
CCCCGAACCCTCTTAACTCTGACCTAGAGACGCCGAGCACCCTGTCCTGCGGGAGCCGCTCTGGGGCGATCTCCCTGGCCCTCTCTGCCCGGCTCACATT
AGCTGTGTGCCAGGCACTTGGGCTGGGCGCATGGCACGCATTGTGCCACCTGCTGACCTAGCTGCTGAAGTGTTGGTATTGTTATGGGGAAGCTCCAGCC
CAGAGAGGTTAGGTGACTGGCCCAAGGTCACACAGCGGCCAGGGACCCCGCTAGATTCGAATCCTGACACCAGGGCTCCCTTGTAGCCTCAGATGGATTT
GGGAGGGCTGCTCCGGCAGGAACCCGCGTTTCAAATGTTCTGGTTATCCCCAGCGCCCTTTCCGCCTCACTTCCCAGCGCAGCGGTGCTGCTCGCGGTCG
GGGGCCGGGACGTGGTTGGGGCTGGGACTGGGGTTGGGGCTGGGACTGGGGCCTGGCTGGCGTCCGCCCCCTCCCACTCGTTGCTCTCCGGCCAGCAG
CT
TGAGCCTGATCGAGTGCGGCCCAGTGCACACCGCCTTCATGGAGAAGGTGTTGGGCAGCCCAGAGGAGGTGCTGGACCGCACGGACATCCACACCTTCCA
CCGCTTCTACCAATA
CCTCGCCCACAGCAAGCAAGTCTTTCGCGAGGCGGCGCAGAACCCTGAGGAGGTGGCGGAGGTGAGCGCCGGGCTGGACTCCAGG
AGTGGGGGCGGTGCGTCCTCCGGCGCGCAGCGGTGGCCACAGCTCTCCTCCCGCCGCCGCAGGTCTTCCTCACCGCTTTGCGCGCCCCGAAGCCGACCCT
GCGCTACTTCACCACCGAGCGCTTCCTGCCCCTGCTGCGGATGCGCCTGGACGACCCCAGCGGCTCCAACTACGTCACCGCCATGCACCGGGAAGTGTTC
GGCGACGTTCCGGCAAAGGCCGAGGCTGGGGCCGAGGCTGGGGGCGGGGCCGGGCCTGGGGCAGAGGACGAGGCCGGGCGCGGTGCGGTGGGGGACCCTG
AGCTCGGCGATCCTCCGGCCGCCCCGCAGTAAAGGCTTCCTCAGCCGCTGTCTCCCGCGCCCTTCTTTGTCCCCTGGGTCTGTGTGGTCCCTGGGGATGG
GGCGGCGGTAGCAGCTGTGGGTGGCTAATTAAGATAGATCGCGTTAGCCAGTTTTACCAGCGCAGCTAGGCGCGATGGCTGTCGCCTGTAATGCCAGCGC
TTTGGGAGGCGGAGGCAGGAGGATCGCTCAAGCCCCGGAGTTGGAGACCAGCCAGAGCAACACAGTGAGACCCCCATCTCTACAAAAATAAAGAAAATTT
  • HSD17B1.F3 (forward primer)
  • HSD17B1.R3 (reverse primer)
  • Intron retention

Frame 0

S*VGLGLG*SQVVTCTPLAMRPQASSLLSLSAF
LSFPFSFLFCFSFVLRRSFTLVAQPGVQ*RGLSS
PQPLPPGFKCS*DCRHVPPRPANFVFLVETRFL
HVGQTGLGLPTSGDPPALASQSAGITGMTHPIR
PSESFLSVKWV**YLSNRF**WWR*CLKVLV*RF
NTQQGLLLE*IVI*LLSHFANV*RRKRAK*IKG
RQPHSPCSAPED*AIPTIWEAASPGGPAGATGL
ATLLQWPIFPEPSGGSQGGRSH**GPVGL*SHCL
NFCGGLVQGRCEQIGG*VRMQQRKGAGVPQEGA
VPRQGFSWV*EGGKAEGDGPLEWAGT*PQKAWE
VETDRSLLELLELCVGH*GKEAGTPP*PAPTSG*
GSSLPVG*CAAPALGGRGLPATPSCQSPCPADP
DRSAIPTASRKATGRGPRWHGFLRPGICSQSRS
RQPPLPLCDSVCTYACMCVPVWCGSQGHPWGWDN
KR*SVTPSLPYIHFFKLVNIHIVNIIFCSPMTS
NST*MPMTPPPKKPHCLPQTPGLYLQLPTQYNT
ST*YNELNVSKPQFHISSPPTGSSPSLLYFTI*Q
LHFSQYWF*KPWSSP*LQSLSPFNQFSSKY*QL
YLCSSKHIPKSPYSRLHTVISPFNYSSSLLTSF
LDSTPAHQQ*NYPRAVKMIF*DGHSGSRL*YQHF
GRWRLADPLRLGVQDHPHQQGETPSLLKIQKLA
GCGGTCL*SQLLGRLRQENCLNPGGGGCSEPES
CHSTPAWARSAKLRLKIK*SSKNDRARWGGTFL*
SEHFGRLRWADRLTSGV*DQPGQHGETPSLLKI
LKISWAWWRVPVIPATREADAGESPEPGRCRMQ
*AKIKTLHSNLSNTLSQK*KKAWETK*DPVSTKK
SKN*LGMVAVMAHTCSPGYLGSFLIFFAETGSH
SVTWPGLELLGSNNPLSWASQSAGITGMSHRAQ
PQSIF*RIEINSHMKRYRQGGLEGSRAGASISIE
LGLRHPLGTFCQPPHVQPSEAPEPCPLGLLWRT
PLAVHD*SMDNCDNVIGQKGSDLSPARPVQILW
AFVQHSFLQGMGQGPTLE*GSYNPQSD*SPALGS
*KEDRRRSERRKAVF*GLRHPNMTT*DCNHGHV
SYELGTLDETSTYTIISHLPTPLLSQPLQQTAV
TIIAPVAQRHTQGNLPRGPLCAHVGTHTCL*SLP
SL*PATRTVCCSKQWAHVCFGSEQGGESGPGTR
RKAYP*DCVGDTTRGGGPQAGRGEAGDIKPRAP
ASPHSLTMARTVVLITGCSSGIGLHLAVRLASDP
SQSFKVYATLRDLKTQGRLWEAARALACPPGSL
ETLQLDVRDSKSVAAARERVTEGRVDVLGEPPG
SIWAPRSLLRPALKPTCSQAQGARGDRPC*G*C*
GGLVGPLVSAVCNAGLGLLGPLEALGEDAVASV
LDVNVVG
TVRMLQAFLPDMKRRGSGRVLVTGSV
GGLMGEW*GVASAAPDSLCAELSLEGRFRGGGGV
GCRQLGGAPSARG*PPGRCASGTSSPHLRAAFQ
*RLLRQQVRARRLMRESGGSAAALWGPVSQHPR
SPNPLNSDLETPSTLSCGSRSGAISLALSARLTL
AVCQALGLGAWHALCHLLT*LLKCWYCYGEAPA
QRG*VTGPRSHSGQGPR*IRILTPGLPCSLRWI
WEGCSGRNPRFKCSGYPQRPFRLTSQRSGAARGR
GPGRGWGWDWGWGWDWGLAGVRPLPLVALRPA
A
*A*SSAAQCTPPSWRRCWAAQRRCWTARTSTPS
TASTN
TSPTASKSFARRRRTLRRWRR*APGWTPG
VGAVRPPARSGGHSSPPAAAGLPHRFARPEADP
ALLHHRALPAPAADAPGRPQRLQLRHRHAPGSV
RRRSGKGRGWGRGWGRGRAWGRGRGRARCGGGP*
ARRSSGRPAVKASSAAVSRALLCPLGLCGPWGW
GGGSSCGWLIKIDRVSQFYQRS*ARWLSPVMPA
LWEAEAGGSLKPRSWRPARATQ*DPHLYKNKEN

Frame 1

VRWDLGWGRVRL*PALH*P*DLRQVPCFL*VLS
FPFPFLFFFVFLLF*DGVSLLLPSLECNSAVSV
HHNLCLPGSSVARIAGMCHHAQLILYF**RRGFS
MLVRLVLDSRPQVIRPPWPLRVLGLQA*PTPSG
PLSLSYL*NGYNNTYLIGFSNGGDNA*KC*YRG
LIPSKDCY*NE**YDYCHILQMCKEERGLSESKG
DSPTHPVLPQRTERSPPSGKLPHQEVQLGLQDW
LLCYNGPSFLSPVEGPRGAEVIDRGQ*GCRATV
*TSVEVWCRGGVNR*EAR*GCSRGRGQECPRRGR
YRGRDSAGSEREGRLRGMALWSGQGHDHRKPGK
WKQTGACWSSWSFVWGTRGRRQALHPDLPLPLD
EGLLCLLDDVLPLLLEEEASQPPPPASRLALLTQ
TDLLSLQHPGRPQGGGPGGMGF*GLGSALSPAL
ANPLCPSVTVCVHMRACVYLCGVAHKVTPGGGI
IRGKV*PPLFRTFIFSSL*IFTLLI*SSAVP*LR
IALRCR*PPHQRNPTVSHRLQVCISNCLLNTTR
PPDTMNLMCLNPNSTFPVLLPAPPPVFSTLLYD
NSIFPNTGFKNPGVVLDSSLSHLSTNSAANTDSS
TFAHQSISPNHPIPDCTLSSLPSITAVAS*LVF
LIPLLPISSEITPEQLK*SFRMGTVAHACNTST
LGGGGWLIPLGWEFKTILTNREKPHLY*KYKN*P
DVVGRVCNPNYLGG*DRRTA*TREVEVAVSQNR
ATALQPGQEARNSVSK*NNLLKMTGPGGVALFY
NPSTLGG*GGQIA*HQGFETSLANMVKLRLY*KY
*KLAGRGGGCL*SQLLGRLMQENRLNQADAGCS
EPRLRHCTPT*AILCLKNKKKPGKQSETPSLQK
SQKISWVWWQ*WHTPVVPATWEAF*YFLQRPGLT
LLPGLVLNSWAPTIPFPGPPKVLGLQA*ATVPS
LKAYFKG*K*TAI*RDTDRAVWKGPEQELLSP*
SWGYVTLWAHSVSLHTFSPQKLPNPVLWAFYGEL
HWLSMTEAWTTVIM*LGKKGLI*AQQGQSRFFG
PLCSIPFSRVWGKDPLWNEDPTTHNQIRVLPWA
AEKRTGEGQRDERLFFEA*GTPT*QRKTVTMVM*
VMS*EPWTKPAHIQSSPTSQRLYFHSLCSKLRS
L*SLLWHRGIPRGICPGGHSVPTWEPTPACKAS
PPSDQQPGQFVVPSSGLMSVLAQNRVGRAGQGPA
GRLILEIAWETQQGVGARRRGGAKQVISSPEPQ
PLPTVSPWPAPWCSSPAVPRASACTWPYVWLQI
HPRASKCMPR*GT*KHRAGCGRRPGPWHALRDPW
RRCSWT*GTQNPWPLPGNA*LRAAWTCWVSLLE
AYGLLGAFSALR*NQHVPRPREHEGTGRAEGDA
EAGWSGLLSPQCVTQAWACWGRWRRWGRTPWPLC
WT*M**
GLCGCCRPSCQT*RGAVRDACW*PGAW
ED*WVSGREWPRQLQILCVRS*ALKAGSAGGVE
WGAVSLEGHRLPGDDPLAAAPQEPRLPT*GLPFN
DVYCASKFALEGLCESLAVLLLPFGVQ*VNTPV
PRTLLTLT*RRRAPCPAGAALGRSPWPSLPGSH
*LCARHLGWAHGTHCATC*PSC*SVGIVMGKLQP
REVR*LAQGHTAARDPARFES*HQGSLVASDGF
GRAAPAGTRVSNVLVIPSALSASLPSAAVLLAV
GGRDVVGAGTGVGAGTGAWLASAPSHSLLSGQQ
L
EPDRVRPSAHRLHGEGVGQPRGGAGPHGHPHLP
PLLPI
PRPQQASLSRGGAEP*GGGGGERRAGLQ
EWGRCVLRRAAVATALLPPPQVFLTALRAPKPTL
RYFTTERFLPLLRMRLDDPSGSNYVTAMHREVF
GDVPAKAEAGAEAGGGAGPGAEDEAGRGAVGDP
ELGDPPAAPQ*RLPQPLSPAPFFVPWVCVVPGDG
AAVAAVGG*LR*IALASFTSAARRDGCRL*CQR
FGRRRQEDRSSPGVGDQPEQHSETPISTKIKKI

Frame 2

LGGTWVGVESGCDLHSISHETSGKFLAFSECFP
FLSLFFSFLFFFCFETEFHSCCPAWSAIARSQF
TTTSASRVQV*LGLQACATTPS*FCIFSRDEVS
PCWSDWSWTPDLR*SARPGLSECWDYRHDPPHPA
L*VFLICKMGIIIPI*SVLVMVEIMPESASIEV
*YPARTVIRMNSNMTTVTFCKCVKKKEG*VNQR
ETAPLTLFCPRGLSDPHHLGSCLTRRSSWGYRTG
YFATMAHLS*AQWRVPGGQKSLIGASRVVEPLS
ELLWRSGAGEV*TDRRLGEDAAEEGGRSAPGGG
GTEAGIQLGLRGREG*GGWPFGVGRDMTTESLGS
GNRQEPAGALGALCGALGEGGRHSTLTCPYLWM
RVFSACWMMCCPCSWRKRPPSHPLLPVALPC*P
RQICYPYSIQEGHREGAQVAWVSEAWDLLSVPLS
PTPFAPL*QCVYICVHVCTCVVWLTRSPLGVG*
*EVKCDPLSSVHSFFQACEYSHC*YNLLQSHDF
E*HLDADDPPTKETPLSPTDSRSVSPTAYSIQHV
HLIQ*T*CV*TPIPHFQSSYRLLPQSSLLYYMT
TPFFPILVLKTLE*SLTPVSLTFQPIQQQILTA
LPLLIKAYPQITLFQTAHCHLSLQLQQ*PPN*FS
*FHSCPSAVKLPQSS*NDLLGWAQWLTPVIPAL
WEVEAG*SP*VGSSRPSSPTGRNPISTKNTKIS
RMWWDVSVIPTTWEAETGELLEPGRWRLQ*ARIV
PQHSSLGKKRETPSQNKIIF*K*QGQVGWHFFI
IRALWEAEVGRSLDIRGLRPAWPTW*NSVSTKN
TKN*LGVVAGACNPSYSGG*CRRIA*TRQMQDAV
SQD*DTALQPKQYFVSKIKKSLGNKVRPRLYKK
VKKLAGYGGSDGTHL*SRLLGKLFNIFCRDRVS
LCYLAWS*TPGLQQSPFLGLPKCWDYRHEPPCPA
SKHILKDRNKQPYEEIQTGRSGRVQSRSFYLHR
VGVTSPSGHILSASTRSALRSSRTLSFGPFMEN
SIGCP*LKHGQL**CDWAKRV*SKPSKASPDSLG
LCAAFLSPGYGARTHSGMRILQPTIRLESCLGQ
LKRGQEKVRETKGCFLRPEAPQHDNVRL*PWSC
EL*ARNPGRNQHIYNHLPPPNAFTFTASAANCGH
YNRSCGTEAYPGESAQGATLCPRGNPHLLVKPP
LPLTSNQDSLLFQAVGSCLFWLRTGWGERARDP
QEGLSLRLRGRHNKGWGPAGGAGRSR*YQAQSPS
LSPQSHHGPHRGAHHRLFLGHRPALGRTSGFRS
IPELQSVCHVEGPENTGPAVGGGPGPGMPSGIP
GDVAAGRKGLKIRGRCPGTRD*GPRGRAG*ASWK
HMGS*EPSPPCVETNMFPGPGSTRGQAVLRVML
RRAGRASCLRSV*RRPGPAGAAGGAGGGRRGLC
AGRECSR
DCADAAGLPARHEEARFGTRVGDRERG
RIDG*VVGSGLGSSRFFVCGAEP*RQVPRGGWS
GVPSAWRGTVCPGMTPWPLRLRNLVSPPKGCLS
MTFIAPASSRSKAYARVWRFCCCPLGSSESTPPF
PEPS*L*PRDAEHPVLREPLWGDLPGPLCPAHI
SCVPGTWAGRMARIVPPADLAAEVLVLLWGSSS
PERLGDWPKVTQRPGTPLDSNPDTRAPL*PQMDL
GGLLRQEPAFQMFWLSPAPFPPHFPAQRCCSRS
GAGTWLGLGLGLGLGLGPGWRPPPPTRCSPASS

LSLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFH
RFYQY
LAHSKQVFREAAQNPEEVAEVSAGLDSR
SGGGASSGAQRWPQLSSRRRRSSSPLCAPRSRP
CATSPPSASCPCCGCAWTTPAAPTTSPPCTGKCS
ATFRQRPRLGPRLGAGPGLGQRTRPGAVRWGTL
SSAILRPPRSKGFLSRCLPRPSLSPGSVWSLGM
GRR*QLWVAN*DRSR*PVLPAQLGAMAVACNASA
LGGGGRRIAQAPELETSQSNTVRPPSLQK*RKF

Sequence HSD17B1.eAug05

AGTTAGGTGGGACTTGGGTTGGGGTAGAGTCAGGTTGTGACCTGCACTCCATTAGCCATGAGACCTCAGGCAAGTTCCTTGCTTTCTCTGAGTGCTTTCC
TTTCCTTTCCCTTTTCTTTTCTTTTTTGTTTTTCTTTTGTTTTGAGACGGAGTTTCACTCTTGTTGCCCAGCCTGGAGTGCAATAGCGCGGTCTCAGTTC
ACCACAACCTCTGCCTCCCGGGTTCAAGTGTAGCTAGGATTGCAGGCATGTGCCACCACGCCCAGCTAATTTTGTATTTTTAGTAGAGACGAGGTTTCTC
CATGTTGGTCAGACTGGTCTTGGACTCCCGACCTCAGGTGATCCGCCCGCCCTGGCCTCTCAGAGTGCTGGGATTACAGGCATGACCCACCCCATCCGGC
CCTCTGAGTCTTTCTTATCTGTAAAATGGGTATAATAATACCTATCTAATCGGTTTTAGTAATGGTGGAGATAATGCCTGAAAGTGCTAGTATAGAGGTT
TAATACCCAGCAAGGACTGTTATTAGAATGAATAGTAATATGACTACTGTCACATTTTGCAAATGTGTAAAGAAGAAAGAGGGCTAAGTGAATCAAAGGG
AGACAGCCCCACTCACCCTGTTCTGCCCCAGAGGACTGAGCGATCCCCACCATCTGGGAAGCTGCCTCACCAGGAGGTCCAGCTGGGGCTACAGGACTGG
CTACTTTGCTACAATGGCCCATCTTTCCTGAGCCCAGTGGAGGGTCCCAGGGGGGCAGAAGTCATTGATAGGGGCCAGTAGGGTTGTAGAGCCACTGTCT
GAACTTCTGTGGAGGTCTGGTGCAGGGGAGGTGTGAACAGATAGGAGGCTAGGTGAGGATGCAGCAGAGGAAGGGGGCAGGAGTGCCCCAGGAGGGGGCG
GTACCGAGGCAGGGATTCAGCTGGGTCTGAGAGGGAGGGAAGGCTGAGGGGGATGGCCCTTTGGAGTGGGCAGGGACATGACCACAGAAAGCCTGGGAAG
TGGAAACAGACAGGAGCCTGCTGGAGCTCTTGGAGCTTTGTGTGGGGCACTAGGGGAAGGAGGCAGGCACTCCACCCTGACCTGCCCCTACCTCTGGATG
AGGGTCTTCTCTGCCTGTTGGATGATGTGCTGCCCCTGCTCTTGGAGGAAGAGGCCTCCCAGCCACCCCCTCCTGCCAGTCGCCTTGCCCTGCTGACCCA
GACAGATCTGCTATCCCTACAGCATCCAGGAAGGCCACAGGGAGGGGGCCCAGGTGGCATGGGTTTCTGAGGCCTGGGATCTGCTCTCAGTCCCGCTCTC
GCCAACCCCCTTTGCCCCTCTGTGACAGTGTGTGTACATATGCGTGCATGTGTGTACCTGTGTGGTGTGGCTCACAAGGTCACCCCTGGGGGTGGGATAA
TAAGAGGTAAAGTGTGACCCCCTCTCTTCCGTACATTCATTTTTTCAAGCTTGTGAATATTCACATTGTTAATATAATCTTCTGCAGTCCCATGACTTCG
AATAGCACTTAGATGCCGATGACCCCCCCACCAAAGAAACCCCACTGTCTCCCACAGACTCCAGGTCTGTATCTCCAACTGCCTACTCAATACAACACGT
CCACCTGATACAATGAACTTAATGTGTCTAAACCCCAATTCCACATTTCCAGTCCTCCTACCGGCTCCTCCCCCAGTCTTCTCTACTTTACTATATGACA
ACTCCATTTTTCCCAATACTGGTTTTAAAAACCCTGGAGTAGTCCTTGACTCCAGTCTCTCTCACCTTTCAACCAATTCAGCAGCAAATACTGACAGCTC
TACCTTTGCTCATCAAAGCATATCCCCAAATCACCCTATTCCAGACTGCACACTGTCATCTCTCCCTTCAATTACAGCAGTAGCCTCCTAACTAGTTTTC
TTGATTCCACTCCTGCCCATCAGCAGTGAAATTACCCCAGAGCAGTTAAAATGATCTTTTAGGATGGGCACAGTGGCTCACGCCTGTAATACCAGCACTT
TGGGAGGTGGAGGCTGGCTGATCCCCTTAGGTTGGGAGTTCAAGACCATCCTCACCAACAGGGAGAAACCCCATCTCTACTAAAAATACAAAAATTAGCC
GGATGTGGTGGGACGTGTCTGTAATCCCAACTACTTGGGAGGCTGAGACAGGAGAACTGCTTGAACCCGGGAGGTGGAGGTTGCAGTGAGCCAGAATCGT
GCCACAGCACTCCAGCCTGGGCAAGAAGCGCGAAACTCCGTCTCAAAATAAAATAATCTTCTAAAAATGACAGGGCCAGGTGGGGTGGCACTTTTTTATA
ATCCGAGCACTTTGGGAGGCTGAGGTGGGCAGATCGCTTGACATCAGGGGTTTGAGACCAGCCTGGCCAACATGGTGAAACTCCGTCTCTACTAAAAATA
CTAAAAATTAGCTGGGCGTGGTGGCGGGTGCCTGTAATCCCAGCTACTCGGGAGGCTGATGCAGGAGAATCGCCTGAACCAGGCAGATGCAGGATGCAGT
GAGCCAAGATTAAGACACTGCACTCCAACCTAAGCAATACTTTGTCTCAAAAATAAAAAAAAGCCTGGGAAACAAAGTGAGACCCCGTCTCTACAAAAAA
GTCAAAAAATTAGCTGGGTATGGTGGCAGTGATGGCACACACCTGTAGTCCCGGCTACTTGGGAAGCTTTTTAATATTTTTTGCAGAGACCGGGTCTCAC
TCTGTTACCTGGCCTGGTCTTGAACTCCTGGGCTCCAACAATCCCCTTTCCTGGGCCTCCCAAAGTGCTGGGATTACAGGCATGAGCCACCGTGCCCAGC
CTCAAAGCATATTTTAAAGGATAGAAATAAACAGCCATATGAAGAGATACAGACAGGGCGGTCTGGAAGGGTCCAGAGCAGGAGCTTCTATCTCCATAGA
GTTGGGGTTACGTCACCCTCTGGGCACATTCTGTCAGCCTCCACACGTTCAGCCCTCAGAAGCTCCCGAACCCTGTCCTTTGGGCCTTTTATGGAGAACT
CCATTGGCTGTCCATGACTGAAGCATGGACAACTGTGATAATGTGATTGGGCAAAAAGGGTCTGATCTAAGCCCAGCAAGGCCAGTCCAGATTCTTTGGG
CCTTTGTGCAGCATTCCTTTCTCCAGGGTATGGGGCAAGGACCCACTCTGGAATGAGGATCCTACAACCCACAATCAGATTAGAGTCCTGCCTTGGGCAG
CTGAAAAGAGGACAGGAGAAGGTCAGAGAGACGAAAGGCTGTTTTTTGAGGCCTGAGGCACCCCAACATGACAACGTAAGACTGTAACCATGGTCATGTG
AGTTATGAGCTAGGAACCCTGGACGAAACCAGCACATATACAATCATCTCCCACCTCCCAACGCCTTTACTTTCACAGCCTCTGCAGCAAACTGCGGTCA
CTATAATCGCTCCTGTGGCACAGAGGCATACCCAGGGGAATCTGCCCAGGGGGCCACTCTGTGCCCACGTGGGAACCCACACCTGCTTGTAAAGCCTCCC
CTCCCTCTGACCAGCAACCAGGACAGTTTGTTGTTCCAAGCAGTGGGCTCATGTCTGTTTTGGCTCAGAACAGGGTGGGGAGAGCGGGCCAGGGACCCGC
AGGAAGGCTTATCCTTGAGATTGCGTGGGAGACACAACAAGGGGTGGGGGCCCGCAGGCGGGGCGGGGCGAAGCAGGTGATATCAAGCCCAGAGCCCCAG
CCTCTCCCCACAGTCTCACCATGGCCCGCACCGTGGTGCTCATCACCGGCTGTTCCTCGGGCATCGGCCTGCACTTGGCCGTACGTCTGGCTTCAGATCC
ATCCCAGAGCTTCAAAGTGTATGCCACGTTGAGGGACCTGAAAACACAGGGCCGGCTGTGGGAGGCGGCCCGGGCCCTGGCATGCCCTCCGGGATCCCTG
GAGACGTTGCAGCTGGACGTAAGGGACTCAAAATCCGTGGCCGCTGCCCGGGAACGCGTGACTGAGGGCCGCGTGGACGTGCTGGTGTGTAACGCAGGCC
TGGGCCTGCTGGGGCCGCTGGAGGCGCTGGGGGAGGACGCCGTGGCCTCTGTGCTGGACGTGAATGTAGTAGGGACTGTGCGGATGCTGCAGGCCTTCCT
GCCAGACATGAAGAGGCGCGGTTCGGGACGCGTGTTGGTGACCGGGAGCGTGGGAGGATTGATGGGTGAGTGGTAGGGAGTGGCCTCGGCAGCTCCAGAT
TCTTTGTGTGCGGAGCTGAGCCTTGAAGGCAGGTTCCGCGGGGGGGGTGGAGTGGGGTGCCGTCAGCTTGGAGGGGCACCGTCTGCCCGGGGATGACCCC
CTGGCCGCTGCGCCTCAGGAACCTCGTCTCCCCACCTAAGGGCTGCCTTTCAATGACGTTTATTGCGCCAGCAAGTTCGCGCTCGAAGGCTTATGCGAGA
GTCTGGCGGTTCTGCTGCTGCCCTTTGGGGTCCAGTGAGTCAACACCCCCGTTCCCCGAACCCTCTTAACTCTGACCTAGAGACGCCGAGCACCCTGTCC
TGCGGGAGCCGCTCTGGGGCGATCTCCCTGGCCCTCTCTGCCCGGCTCACATTAGCTGTGTGCCAGGCACTTGGGCTGGGCGCATGGCACGCATTGTGCC
ACCTGCTGACCTAGCTGCTGAAGTGTTGGTATTGTTATGGGGAAGCTCCAGCCCAGAGAGGTTAGGTGACTGGCCCAAGGTCACACAGCGGCCAGGGACC
CCGCTAGATTCGAATCCTGACACCAGGGCTCCCTTGTAGCCTCAGATGGATTTGGGAGGGCTGCTCCGGCAGGAACCCGCGTTTCAAATGTTCTGGTTAT
CCCCAGCGCCCTTTCCGCCTCACTTCCCAGCGCAGCGGTGCTGCTCGCGGTCGGGGGCCGGGACGTGGTTGGGGCTGGGACTGGGGTTGGGGCTGGGACT
GGGGCCTGGCTGGCGTCCGCCCCCTCCCACTCGTTGCTCTCCGGCCAGCAG
CTTGAGCCTGATCGAGTGCGGCCCAGTGCACACCGCCTTCATGGAGAAG
GTGTTGGGCAGCCCAGAGGAGGTGCTGGACCGCACGGACATCCACACCTTCCACCGCTTCTACCAATACCTCGCCCACAGCAAGCAAGTCTTTCGCGAGG
CGGCGCAGAACCCTGAGGAGGTGGCGGAGGTGAGCGCCGGGCTGGACTCCAGGAGTGGGGGCGGTGCGTCCTCCGGCGCGCAGCGGTGGCCACAGCTCTC
CTCCCGCCGCCGCAGGTCTTCCTCACCGCTTTGCGCGCCCCGAAGCCGACCCTGCGCTACTTCACCACCGAGCGCTTCCTGCCCCTGCTGCGGATGCGCC
TGGACGACCCCAGCGGCTCCAACTACGTCACCGCCATGCACCGGGAAGTGTTCGGCGACGTTCCGGCAAAGGCCGAGGCTGGGGCCGAGGCTGGGGGCGG
GGCCGGGCCTGGGGCAGAGGACGAGGCCGGGCGCGGTGCGGTGGGGGACCCTGAGCTCGGCGATCCTCCGGCCGCCCCGCAGTAAAGGCTTCCTCAGCCG
CTGTCTCCCGCGCCCTTCTTTGTCCCCTGGGTCTGTGTGGTCCCTGGGGATGGGGCGGCGGTAGCAGCTGTGGGTGGCTAATTAAGATAGATCGCGTTAG
CCAGTTTTACCAGCGCAGCTAGGCGCGATGGCTGTCGCCTGTAATGCCAGCGCTTTGGGAGGCGGAGGCAGGAGGATCGCTCAAGCCCCGGAGTTGGAGA
CCAGCCAGAGCAACACAGTGAGACCCCCATCTCTACAAAAATAAAGAAAATTT
  • HSD17B1.F3 (forward primer)
  • HSD17B1.R3 (reverse primer)
  • Intron retention

Frame 0

S*VGLGLG*SQVVTCTPLAMRPQASSLLSLSAF
LSFPFSFLFCFSFVLRRSFTLVAQPGVQ*RGLSS
PQPLPPGFKCS*DCRHVPPRPANFVFLVETRFL
HVGQTGLGLPTSGDPPALASQSAGITGMTHPIR
PSESFLSVKWV**YLSNRF**WWR*CLKVLV*RF
NTQQGLLLE*IVI*LLSHFANV*RRKRAK*IKG
RQPHSPCSAPED*AIPTIWEAASPGGPAGATGL
ATLLQWPIFPEPSGGSQGGRSH**GPVGL*SHCL
NFCGGLVQGRCEQIGG*VRMQQRKGAGVPQEGA
VPRQGFSWV*EGGKAEGDGPLEWAGT*PQKAWE
VETDRSLLELLELCVGH*GKEAGTPP*PAPTSG*
GSSLPVG*CAAPALGGRGLPATPSCQSPCPADP
DRSAIPTASRKATGRGPRWHGFLRPGICSQSRS
RQPPLPLCDSVCTYACMCVPVWCGSQGHPWGWDN
KR*SVTPSLPYIHFFKLVNIHIVNIIFCSPMTS
NST*MPMTPPPKKPHCLPQTPGLYLQLPTQYNT
ST*YNELNVSKPQFHISSPPTGSSPSLLYFTI*Q
LHFSQYWF*KPWSSP*LQSLSPFNQFSSKY*QL
YLCSSKHIPKSPYSRLHTVISPFNYSSSLLTSF
LDSTPAHQQ*NYPRAVKMIF*DGHSGSRL*YQHF
GRWRLADPLRLGVQDHPHQQGETPSLLKIQKLA
GCGGTCL*SQLLGRLRQENCLNPGGGGCSEPES
CHSTPAWARSAKLRLKIK*SSKNDRARWGGTFL*
SEHFGRLRWADRLTSGV*DQPGQHGETPSLLKI
LKISWAWWRVPVIPATREADAGESPEPGRCRMQ
*AKIKTLHSNLSNTLSQK*KKAWETK*DPVSTKK
SKN*LGMVAVMAHTCSPGYLGSFLIFFAETGSH
SVTWPGLELLGSNNPLSWASQSAGITGMSHRAQ
PQSIF*RIEINSHMKRYRQGGLEGSRAGASISIE
LGLRHPLGTFCQPPHVQPSEAPEPCPLGLLWRT
PLAVHD*SMDNCDNVIGQKGSDLSPARPVQILW
AFVQHSFLQGMGQGPTLE*GSYNPQSD*SPALGS
*KEDRRRSERRKAVF*GLRHPNMTT*DCNHGHV
SYELGTLDETSTYTIISHLPTPLLSQPLQQTAV
TIIAPVAQRHTQGNLPRGPLCAHVGTHTCL*SLP
SL*PATRTVCCSKQWAHVCFGSEQGGESGPGTR
RKAYP*DCVGDTTRGGGPQAGRGEAGDIKPRAP
ASPHSLTMARTVVLITGCSSGIGLHLAVRLASDP
SQSFKVYATLRDLKTQGRLWEAARALACPPGSL
ETLQLDVRDSKSVAAARERVTEGRVDVLVCNAG
LGLLGPLEALGEDAVASVLDVNVVGTVRMLQAFL
PDMKRRGSGRVLVTGSVGGLMGEW*GVASAAPD
SLCAELSLEGRFRGGGGVGCRQLGGAPSARG*P
PGRCASGTSSPHLRAAFQ*RLLRQQVRARRLMRE
SGGSAAALWGPVSQHPRSPNPLNSDLETPSTLS
CGSRSGAISLALSARLTLAVCQALGLGAWHALC
HLLT*LLKCWYCYGEAPAQRG*VTGPRSHSGQGP
R*IRILTPGLPCSLRWIWEGCSGRNPRFKCSGY
PQRPFRLTSQRSGAARGRGPGRGWGWDWGWGWD
WGLAGVRPLPLVALRPA
A*A*SSAAQCTPPSWRR
CWAAQRRCWTARTSTPSTASTNTSPTASKSFAR
RRRTLRRWRR*APGWTPGVGAVRPPARSGGHSS
PPAAAGLPHRFARPEADPALLHHRALPAPAADAP
GRPQRLQLRHRHAPGSVRRRSGKGRGWGRGWGR
GRAWGRGRGRARCGGGP*ARRSSGRPAVKASSA
AVSRALLCPLGLCGPWGWGGGSSCGWLIKIDRVS
QFYQRS*ARWLSPVMPALWEAEAGGSLKPRSWR
PARATQ*DPHLYKNKEN

Frame 1

VRWDLGWGRVRL*PALH*P*DLRQVPCFL*VLS
FPFPFLFFFVFLLF*DGVSLLLPSLECNSAVSV
HHNLCLPGSSVARIAGMCHHAQLILYF**RRGFS
MLVRLVLDSRPQVIRPPWPLRVLGLQA*PTPSG
PLSLSYL*NGYNNTYLIGFSNGGDNA*KC*YRG
LIPSKDCY*NE**YDYCHILQMCKEERGLSESKG
DSPTHPVLPQRTERSPPSGKLPHQEVQLGLQDW
LLCYNGPSFLSPVEGPRGAEVIDRGQ*GCRATV
*TSVEVWCRGGVNR*EAR*GCSRGRGQECPRRGR
YRGRDSAGSEREGRLRGMALWSGQGHDHRKPGK
WKQTGACWSSWSFVWGTRGRRQALHPDLPLPLD
EGLLCLLDDVLPLLLEEEASQPPPPASRLALLTQ
TDLLSLQHPGRPQGGGPGGMGF*GLGSALSPAL
ANPLCPSVTVCVHMRACVYLCGVAHKVTPGGGI
IRGKV*PPLFRTFIFSSL*IFTLLI*SSAVP*LR
IALRCR*PPHQRNPTVSHRLQVCISNCLLNTTR
PPDTMNLMCLNPNSTFPVLLPAPPPVFSTLLYD
NSIFPNTGFKNPGVVLDSSLSHLSTNSAANTDSS
TFAHQSISPNHPIPDCTLSSLPSITAVAS*LVF
LIPLLPISSEITPEQLK*SFRMGTVAHACNTST
LGGGGWLIPLGWEFKTILTNREKPHLY*KYKN*P
DVVGRVCNPNYLGG*DRRTA*TREVEVAVSQNR
ATALQPGQEARNSVSK*NNLLKMTGPGGVALFY
NPSTLGG*GGQIA*HQGFETSLANMVKLRLY*KY
*KLAGRGGGCL*SQLLGRLMQENRLNQADAGCS
EPRLRHCTPT*AILCLKNKKKPGKQSETPSLQK
SQKISWVWWQ*WHTPVVPATWEAF*YFLQRPGLT
LLPGLVLNSWAPTIPFPGPPKVLGLQA*ATVPS
LKAYFKG*K*TAI*RDTDRAVWKGPEQELLSP*
SWGYVTLWAHSVSLHTFSPQKLPNPVLWAFYGEL
HWLSMTEAWTTVIM*LGKKGLI*AQQGQSRFFG
PLCSIPFSRVWGKDPLWNEDPTTHNQIRVLPWA
AEKRTGEGQRDERLFFEA*GTPT*QRKTVTMVM*
VMS*EPWTKPAHIQSSPTSQRLYFHSLCSKLRS
L*SLLWHRGIPRGICPGGHSVPTWEPTPACKAS
PPSDQQPGQFVVPSSGLMSVLAQNRVGRAGQGPA
GRLILEIAWETQQGVGARRRGGAKQVISSPEPQ
PLPTVSPWPAPWCSSPAVPRASACTWPYVWLQI
HPRASKCMPR*GT*KHRAGCGRRPGPWHALRDPW
RRCSWT*GTQNPWPLPGNA*LRAAWTCWCVTQA
WACWGRWRRWGRTPWPLCWT*M**GLCGCCRPS
CQT*RGAVRDACW*PGAWED*WVSGREWPRQLQI
LCVRS*ALKAGSAGGVEWGAVSLEGHRLPGDDP
LAAAPQEPRLPT*GLPFNDVYCASKFALEGLCE
SLAVLLLPFGVQ*VNTPVPRTLLTLT*RRRAPCP
AGAALGRSPWPSLPGSH*LCARHLGWAHGTHCA
TC*PSC*SVGIVMGKLQPREVR*LAQGHTAARD
PARFES*HQGSLVASDGFGRAAPAGTRVSNVLVI
PSALSASLPSAAVLLAVGGRDVVGAGTGVGAGT
GAWLASAPSHSLLSGQQ
LEPDRVRPSAHRLHGE
GVGQPRGGAGPHGHPHLPPLLPIPRPQQASLSRG
GAEP*GGGGGERRAGLQEWGRCVLRRAAVATAL
LPPPQVFLTALRAPKPTLRYFTTERFLPLLRMR
LDDPSGSNYVTAMHREVFGDVPAKAEAGAEAGGG
AGPGAEDEAGRGAVGDPELGDPPAAPQ*RLPQP
LSPAPFFVPWVCVVPGDGAAVAAVGG*LR*IAL
ASFTSAARRDGCRL*CQRFGRRRQEDRSSPGVGD
QPEQHSETPISTKIKKI

Frame 2

LGGTWVGVESGCDLHSISHETSGKFLAFSECFP
FLSLFFSFLFFFCFETEFHSCCPAWSAIARSQF
TTTSASRVQV*LGLQACATTPS*FCIFSRDEVS
PCWSDWSWTPDLR*SARPGLSECWDYRHDPPHPA
L*VFLICKMGIIIPI*SVLVMVEIMPESASIEV
*YPARTVIRMNSNMTTVTFCKCVKKKEG*VNQR
ETAPLTLFCPRGLSDPHHLGSCLTRRSSWGYRTG
YFATMAHLS*AQWRVPGGQKSLIGASRVVEPLS
ELLWRSGAGEV*TDRRLGEDAAEEGGRSAPGGG
GTEAGIQLGLRGREG*GGWPFGVGRDMTTESLGS
GNRQEPAGALGALCGALGEGGRHSTLTCPYLWM
RVFSACWMMCCPCSWRKRPPSHPLLPVALPC*P
RQICYPYSIQEGHREGAQVAWVSEAWDLLSVPLS
PTPFAPL*QCVYICVHVCTCVVWLTRSPLGVG*
*EVKCDPLSSVHSFFQACEYSHC*YNLLQSHDF
E*HLDADDPPTKETPLSPTDSRSVSPTAYSIQHV
HLIQ*T*CV*TPIPHFQSSYRLLPQSSLLYYMT
TPFFPILVLKTLE*SLTPVSLTFQPIQQQILTA
LPLLIKAYPQITLFQTAHCHLSLQLQQ*PPN*FS
*FHSCPSAVKLPQSS*NDLLGWAQWLTPVIPAL
WEVEAG*SP*VGSSRPSSPTGRNPISTKNTKIS
RMWWDVSVIPTTWEAETGELLEPGRWRLQ*ARIV
PQHSSLGKKRETPSQNKIIF*K*QGQVGWHFFI
IRALWEAEVGRSLDIRGLRPAWPTW*NSVSTKN
TKN*LGVVAGACNPSYSGG*CRRIA*TRQMQDAV
SQD*DTALQPKQYFVSKIKKSLGNKVRPRLYKK
VKKLAGYGGSDGTHL*SRLLGKLFNIFCRDRVS
LCYLAWS*TPGLQQSPFLGLPKCWDYRHEPPCPA
SKHILKDRNKQPYEEIQTGRSGRVQSRSFYLHR
VGVTSPSGHILSASTRSALRSSRTLSFGPFMEN
SIGCP*LKHGQL**CDWAKRV*SKPSKASPDSLG
LCAAFLSPGYGARTHSGMRILQPTIRLESCLGQ
LKRGQEKVRETKGCFLRPEAPQHDNVRL*PWSC
EL*ARNPGRNQHIYNHLPPPNAFTFTASAANCGH
YNRSCGTEAYPGESAQGATLCPRGNPHLLVKPP
LPLTSNQDSLLFQAVGSCLFWLRTGWGERARDP
QEGLSLRLRGRHNKGWGPAGGAGRSR*YQAQSPS
LSPQSHHGPHRGAHHRLFLGHRPALGRTSGFRS
IPELQSVCHVEGPENTGPAVGGGPGPGMPSGIP
GDVAAGRKGLKIRGRCPGTRD*GPRGRAGV*RRP
GPAGAAGGAGGGRRGLCAGRECSRDCADAAGLP
ARHEEARFGTRVGDRERGRIDG*VVGSGLGSSR
FFVCGAEP*RQVPRGGWSGVPSAWRGTVCPGMTP
WPLRLRNLVSPPKGCLSMTFIAPASSRSKAYAR
VWRFCCCPLGSSESTPPFPEPS*L*PRDAEHPV
LREPLWGDLPGPLCPAHISCVPGTWAGRMARIVP
PADLAAEVLVLLWGSSSPERLGDWPKVTQRPGT
PLDSNPDTRAPL*PQMDLGGLLRQEPAFQMFWL
SPAPFPPHFPAQRCCSRSGAGTWLGLGLGLGLGL
GPGWRPPPPTRCSPASS
LSLIECGPVHTAFMEK
VLGSPEEVLDRTDIHTFHRFYQYLAHSKQVFRE
AAQNPEEVAEVSAGLDSRSGGGASSGAQRWPQLS
SRRRRSSSPLCAPRSRPCATSPPSASCPCCGCA
WTTPAAPTTSPPCTGKCSATFRQRPRLGPRLGA
GPGLGQRTRPGAVRWGTLSSAILRPPRSKGFLSR
CLPRPSLSPGSVWSLGMGRR*QLWVAN*DRSR*
PVLPAQLGAMAVACNASALGGGGRRIAQAPELE
TSQSNTVRPPSLQK*RKF

Sequence HSD17B1.cAug05

AGGACCCACTCTGGAATGAGGATCCTACAACCCACAATCAGATTAGAGTCCTGCCTTGGGCAGCTGAAAAGAGGACAGGAGAAGGTCAGAGAGACGAAAG
GCTGTTTTTTGAGGCCTGAGGCACCCCAACATGACAACGTAAGACTGTAACCATGGTCATGTGAGTTATGAGCTAGGAACCCTGGACGAAACCAGCACAT
ATACAATCATCTCCCACCTCCCAACGCCTTTACTTTCACAGCCTCTGCAGCAAACTGCGGTCACTATAATCGCTCCTGTGGCACAGAGGCATACCCAGGG
GAATCTGCCCAGGGGGCCACTCTGTGCCCACGTGGGAACCCACACCTGCTTGTAAAGCCTCCCCTCCCTCTGACCAGCAACCAGGACAGTTTGTTGTTCC
AAGCAGTGGGCTCATGTCTGTTTTGGCTCAGAACAGGGTGGGGAGAGCGGGCCAGGGACCCGCAGGAAGGCTTATCCTTGAGATTGCGTGGGAGACACAA
CAAGGGGTGGGGGCCCGCAGGCGGGGCGGGGCGAAGCAGGTGATATCAAGCCCAGAGCCCCAGCCTCTCCCCACAGTCTCACCATGGCCCGCACCGTGGT
GCTCATCACCGGCTGTTCCTCGGGCATCGGCCTGCACTTGGCCGTACGTCTGGCTTCAGATCCATCCCAGAGCTTCAAAGGTATAGATAGGCAGGGACAG
GGAGGGAGAGAAGGGAGGAGCCCTTGGAGGCCAGAAGGGAAGTCAGATCTTCCTCCTCTCCCAAAACCTCCAGTGTATGCCACGTTGAGGGACCTGAAAA
CACAGGGCCGGCTGTGGGAGGCGGCCCGGGCCCTGGCATGCCCTCCGGGATCCCTGGAGACGTTGCAGCTGGACGTAAGGGACTCAAAATCCGTGGCCGC
TGCCCGGGAACGCGTGACTGAGGGCCGCGTGGACGTGCTGGGTGAGCCTCCTGGAAGCATATGGGCTCCTAGGAGCCTTCTCCGCCCTGCGTTGAAACCA
ACATGTTCCCAGGCCCAGGGAGCACGAGGGGACAGGCCGTGCTGAGGGTGATGCTGAGGCGGGCTGGTCGGGCCTCTTGTCTCCGCAGTGTGTAACGCAG
GCCTGGGCCTGCTGGGGCCGCTGGAGGCGCTGGGGGAGGACGCCGTGGCCTCTGTGCTGGACGTGAATGTAGTAGGGACTGTGCGGATGCTGCAGGCCTT
CCTGCCAGACATGAAGAGGCGCGGTTCGGGACGCGTGTTGGTGACCGGGAGCGTGGGAGGATTGATGGGTGAGTGGTAGGGAGTGGCCTCGGCAGCTCCA
GATTCTTTGTGTGCGGAGCTGAGCCTTGAAGGCAGGTTCCGCGGGGGGGGTGGAGTGGGGTGCCGTCAGCTTGGAGGGGCACCGTCTGCCCGGGGATGAC
CCCCTGGCCGCTGCGCCTCAGGAACCTCGTCTCCCCACCTAAGGGCTGCCTTTCAATGACGTTTATTGCGCCAGCAAGTTCGCGCTCGAAGGCTTATGCG
AGAGTCTGGCGGTTCTGCTGCTGCCCTTTGGGGTCCAGTGAGTCAACACCCCCGTTCCCCGAACCCTCTTAACTCTGACCTAGAGACGCCGAGCACCCTG
TCCTGCGGGAGCCGCTCTGGGGCGATCTCCCTGGCCCTCTCTGCCCGGCTCACATTAGCTGTGTGCCAGGCACTTGGGCTGGGCGCATGGCACGCATTGT
GCCACCTGCTGACCTAGCTGCTGAAGTGTTGGTATTGTTATGGGGAAGCTCCAGCCCAGAGAGGTTAGGTGACTGGCCCAAGGTCACACAGCGGCCAGGG
ACCCCGCTAGATTCGAATCCTGACACCAGGGCTCCCTTGTAGCCTCAGATGGATTTGGGAGGGCTGCTCCGGCAGGAACCCGCGTTTCAAATGTTCTGGT
TATCCCCAGCGCCCTTTCCGCCTCACTTCCCAGCGCAGCGGTGCTGCTCGCGGTCGGGGGCCGGGACGTGGTTGGGGCTGGGACTGGGGTTGGGGCTGGG
ACTGGGGCCTGGCTGGCGTCCGCCCCCTCCCACTCGTTGCTCTCCGGCCAGCAG
CTTGAGCCTGATCGAGTGCGGCCCAGTGCACACCGCCTTCATGGAG
AAGGTGTTGGGCAGCCCAGAGGAGGTGCTGGACCGCACGGACATCCACACCTTCCACCGCTTCTACCAATACCTCGCCCACAGCAAGCAAGTCTTTCGCG
AGGCGGCGCAGAACCCTGAGGAGGTGGCGGAGGTCTTCCTCACCGCTTTGCGCGCCCCGAAGCCGACCCTGCGCTACTTCACCACCGAGCGCTTCCTGCC
CCTGCTGCGGATGCGCCTGGACGACCCCAGCGGCTCCAACTACGTCACCGCCATGCACCGGGAAGTGTTCGGCGACGTTCCGGCAAAGGCCGAGGCTGGG
GCCGAGGCTGGGGGCGGGGCCGGGCCTGGGGCAGAGGACGAGGCCGGGCGCGGTGCGGTGGGGGACCCTGAGCTCGGCGATCCTCCGGCCGCCCCGCAGT
AAAGGCTTCCTCAGCCGCTGTCTCCCGCGCCCTTCTTTGTCCCCTGGGTCTGTGTGGTCCCTGGGGATGGGGCGGCGGTAGCAGCTGTGGGTGGCTAATT
AAGATAGATCGCGTTAGCCAGTTTTACCAGCGCAGCTAGGCGCGATGGCTGTCGCCTGTAATGCCAGCGCTTTGGGAGGCGGAGGCAGGAGGATCGCTCA
AGCCCCGGAGTTGGAGACCAGCCAGAGCAACACAGTGAGACCCCCATCTCTACAAAAATAAAGAAAATTTAAAAATCAG
  • HSD17B1.F3 (forward primer)
  • HSD17B1.R3 (reverse primer)
  • Intron retention

Frame 0

RTHSGMRILQPTIRLESCLGQLKRGQEKVRETK
GCFLRPEAPQHDNVRL*PWSCEL*ARNPGRNQHI
YNHLPPPNAFTFTASAANCGHYNRSCGTEAYPG
ESAQGATLCPRGNPHLLVKPPLPLTSNQDSLLF
QAVGSCLFWLRTGWGERARDPQEGLSLRLRGRHN
KGWGPAGGAGRSR*YQAQSPSLSPQSHHGPHRG
AHHRLFLGHRPALGRTSGFRSIPELQRYR*AGT
GRERREEPLEARREVRSSSSPKTSSVCHVEGPEN
TGPAVGGGPGPGMPSGIPGDVAAGRKGLKIRGR
CPGTRD*GPRGRAG*ASWKHMGS*EPSPPCVET
NMFPGPGSTRGQAVLRVMLRRAGRASCLRSV*RR
PGPAGAAGGAGGGRRGLCAGRECSRDCADAAGL
PARHEEARFGTRVGDRERGRIDG*VVGSGLGSS
RFFVCGAEP*RQVPRGGWSGVPSAWRGTVCPGMT
PWPLRLRNLVSPPKGCLSMTFIAPASSRSKAYA
RVWRFCCCPLGSSESTPPFPEPS*L*PRDAEHP
VLREPLWGDLPGPLCPAHISCVPGTWAGRMARIV
PPADLAAEVLVLLWGSSSPERLGDWPKVTQRPG
TPLDSNPDTRAPL*PQMDLGGLLRQEPAFQMFW
LSPAPFPPHFPAQRCCSRSGAGTWLGLGLGLGLG
LGPGWRPPPPTRCSPASS
LSLIECGPVHTAFME
KVLGSPEEVLDRTDIHTFHRFYQYLAHSKQVFR
EAAQNPEEVAEVFLTALRAPKPTLRYFTTERFLP
LLRMRLDDPSGSNYVTAMHREVFGDVPAKAEAG
AEAGGGAGPGAEDEAGRGAVGDPELGDPPAAPQ
*RLPQPLSPAPFFVPWVCVVPGDGAAVAAVGG*L
R*IALASFTSAARRDGCRL*CQRFGRRRQEDRS
SPGVGDQPEQHSETPISTKIKKI*KS

Frame 1

GPTLE*GSYNPQSD*SPALGS*KEDRRRSERRK
AVF*GLRHPNMTT*DCNHGHVSYELGTLDETST
YTIISHLPTPLLSQPLQQTAVTIIAPVAQRHTQG
NLPRGPLCAHVGTHTCL*SLPSL*PATRTVCCS
KQWAHVCFGSEQGGESGPGTRRKAYP*DCVGDT
TRGGGPQAGRGEAGDIKPRAPASPHSLTMARTVV
LITGCSSGIGLHLAVRLASDPSQSFKGIDRQGQ
GGREGRSPWRPEGKSDLPPLPKPPVYATLRDLK
TQGRLWEAARALACPPGSLETLQLDVRDSKSVAA
ARERVTEGRVDVLGEPPGSIWAPRSLLRPALKP
TCSQAQGARGDRPC*G*C*GGLVGPLVSAVCNA
GLGLLGPLEALGEDAVASVLDVNVVGTVRMLQAF
LPDMKRRGSGRVLVTGSVGGLMGEW*GVASAAP
DSLCAELSLEGRFRGGGGVGCRQLGGAPSARG*
PPGRCASGTSSPHLRAAFQ*RLLRQQVRARRLMR
ESGGSAAALWGPVSQHPRSPNPLNSDLETPSTL
SCGSRSGAISLALSARLTLAVCQALGLGAWHAL
CHLLT*LLKCWYCYGEAPAQRG*VTGPRSHSGQG
PR*IRILTPGLPCSLRWIWEGCSGRNPRFKCSG
YPQRPFRLTSQRSGAARGRGPGRGWGWDWGWGW
DWGLAGVRPLPLVALRPA
A*A*SSAAQCTPPSWR
RCWAAQRRCWTARTSTPSTASTNTSPTASKSFA
RRRRTLRRWRRSSSPLCAPRSRPCATSPPSASC
PCCGCAWTTPAAPTTSPPCTGKCSATFRQRPRLG
PRLGAGPGLGQRTRPGAVRWGTLSSAILRPPRS
KGFLSRCLPRPSLSPGSVWSLGMGRR*QLWVAN
*DRSR*PVLPAQLGAMAVACNASALGGGGRRIAQ
APELETSQSNTVRPPSLQK*RKFKNQ

Frame 2

DPLWNEDPTTHNQIRVLPWAAEKRTGEGQRDER
LFFEA*GTPT*QRKTVTMVM*VMS*EPWTKPAH
IQSSPTSQRLYFHSLCSKLRSL*SLLWHRGIPR
GICPGGHSVPTWEPTPACKASPPSDQQPGQFVVP
SSGLMSVLAQNRVGRAGQGPAGRLILEIAWETQ
QGVGARRRGGAKQVISSPEPQPLPTVSPWPAPW
CSSPAVPRASACTWPYVWLQIHPRASKV*IGRDR
EGEKGGALGGQKGSQIFLLSQNLQCMPR*GT*K
HRAGCGRRPGPWHALRDPWRRCSWT*GTQNPWP
LPGNA*LRAAWTCWVSLLEAYGLLGAFSALR*NQ
HVPRPREHEGTGRAEGDAEAGWSGLLSPQCVTQ
AWACWGRWRRWGRTPWPLCWT*M**GLCGCCRP
SCQT*RGAVRDACW*PGAWED*WVSGREWPRQLQ
ILCVRS*ALKAGSAGGVEWGAVSLEGHRLPGDD
PLAAAPQEPRLPT*GLPFNDVYCASKFALEGLC
ESLAVLLLPFGVQ*VNTPVPRTLLTLT*RRRAPC
PAGAALGRSPWPSLPGSH*LCARHLGWAHGTHC
ATC*PSC*SVGIVMGKLQPREVR*LAQGHTAAR
DPARFES*HQGSLVASDGFGRAAPAGTRVSNVLV
IPSALSASLPSAAVLLAVGGRDVVGAGTGVGAG
TGAWLASAPSHSLLSGQQ
LEPDRVRPSAHRLHG
EGVGQPRGGAGPHGHPHLPPLLPIPRPQQASLSR
GGAEP*GGGGGLPHRFARPEADPALLHHRALPA
PAADAPGRPQRLQLRHRHAPGSVRRRSGKGRGW
GRGWGRGRAWGRGRGRARCGGGP*ARRSSGRPAV
KASSAAVSRALLCPLGLCGPWGWGGGSSCGWLI
KIDRVSQFYQRS*ARWLSPVMPALWEAEAGGSL
KPRSWRPARATQ*DPHLYKNKENLKI

Copyright ©2008,2017, all rights reserved.