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Sequences

Sequence CTDP1.eAug05

GAGGTGCAGCCGAGTGAGGGCCTTGGTGGGGTGCAGCCGGGTGAGGGCCCTGGTGGGGTACAGCTGGGTGAGGGCCCTGAGCCCTGCAGGGGTGCAGTCA GGTGAAGGCCCTGGTGGGATGCAGCCGAGTGAGGGCCCTGAGCCCTGGTGGGGTACAGCCAGGTGAGGGCCCTGGTGGGTGCAGCCGGATGTGGGCCCTG AGCCTCCAGTGCTGGCCGGAACAGCCTGACGCAGCCGGGTCTCCTGCAGGCACAGAGAAGGTGCTGCAGGCACAGGAGTGCGGACACCTGCACGTGGTCA ACCCTGACTGGCTGTGGAGCTGCCTGGAGCGCTGGGACAAGGTGGAGGAGCAGCTCTTCCCGCTCAGGGACGATCACACCAAGGCACAGAGGGAGAACAG CCCTGCGGCCTTTCCCGACCGGGAGGGTGTGCCCCCCACCGCCTTGTTCCACCCGATGCCGGTTCTTCCCAAGGCCCAGCCTGGCCCCGAGGTTCGGATC TACGACTCCAACACGGGGAAGCTCATCAGGACGGGCGCCCGGGGGCCCCCAGCACCCTCCAGCTCCCTACCCATCCGCCAGGAGCCCTCTTCCTTCAGAG GCCACAAGAGGAAGCTGAATGAAGAGGACGCCGCCAGCGAGTCCAGCAGGGAGTCCAGCAACGAGGATGAGGGCAGCAGCTCCGAGGCCGACGAGATGGC CAAGGCGCTGGAGGCGGAGCTCAACGACCTCATGTGAGCGCGGGCAGCGGGCAGGGACTGAAGCCTGACCGACCTCCAGCAGCACTCGGACGTCCCCGGA CCAGCCCTCAGTCTCGGTCCACGCTGCTTTCTTCCCAAAGGACATGTATATTTGCAGAGCTCCACATACAGAAACACATTATTTTGCAGAAATAGGTGTT TTTAAGAAGTTTTACTACAGGAATGTCTACTTTTGTAAGTGACAGGTGTTAAAGGCCCAGGTGTGCTGTGCCAAAGAGCTCAGCAGAGGCTCACGTGGCC CAGGCTGGTGCGCCCGCTGTCTCGGTAAGGGGCGGGTTGGTGTGTTTTCCCCTTGTGTACCAGAGCACATTCCTTAGGGGACGGCTTTGGGGGTCCCACG AGACATGGACTAGGAGTTTAAGCAGGACAGTGTGCGTGCACGAGCTCCGAGCCCAGCACAGACATGCCTGGAACCCCCGCCGCCTGCTGCTCCCTCCTAG GGAACCCATTTCCGGGGAACGCCGTGACTGTCGGGCAGCCTGGAGCTTCCTGCAGCCTCCTACGCAGGGTCCACGCCACGTGGCCTGGGCTGCCATCCTG CCGTCCTCCCACTGGCATCCTGGCAAGGGGGCGTTGCTTTTCCTGGGCGGCCTTTTATGTCTTGGAGACACCTGATGTAAAGTTTCTGTAAATCTATTTC ATATCTGACCCACCAAACAGATTTCTCTTTAATAAAAATCCTTTTTGTAAGTTCTCT

CTDP1.F7 (forward primer)
CTDP1.R7 (reverse primer)
Multiple exon skipping

Frame 0

EVQPSEGLGGVQPGEGPGGVQLGEGPEPCRGAV R*RPWWDAAE*GP*ALVGYSQVRALVGAAGCGP* ASSAGRNSLTQPGLLQAQRRCCRHRSADTCTWS TLTGCGAAWSAGTRWRSSSSRSGTITPRHRGRT ALRPFPTGRVCPPPPCSTRCRFFPRPSLAPRFGS TTPTRGSSSGRAPGGPQHPPAPYPSARSPLPSE ATRGS*MKRTPPASPAGSPATRMRAAAPRPTRW PRRWRRSSTTSCERGQRAGTEA*PTSSSTRTSPD QPSVSVHAAFFPKDMYICRAPHTETHYFAEIGV FKKFYYRNVYFCK*QVLKAQVCCAKELSRGSRG PGWCARCLGKGRVGVFSPCVPEHIP*GTALGVPR DMD*EFKQDSVRARAPSPAQTCLEPPPPAAPS* GTHFRGTP*LSGSLELPAASYAGSTPRGLGCHP AVLPLASWQGGVAFPGRPFMSWRHLM*SFCKSIS YLTHQTDFSLIKILFVSS

Frame 1

RCSRVRALVGCSRVRALVGYSWVRALSPAGVQS GEGPGGMQPSEGPEPWWGTAR*GPWWVQPDVGP EPPVLAGTA*RSRVSCRHREGAAGTGVRTPARGQ P*LAVELPGALGQGGGAALPAQGRSHQGTEGEQ PCGLSRPGGCAPHRLVPPDAGSSQGPAWPRGSD LRLQHGEAHQDGRPGAPSTLQLPTHPPGALFLQR PQEEAE*RGRRQRVQQGVQQRG*GQQLRGRRDG QGAGGGAQRPHVSAGSGQGLKPDRPPAALGRPR TSPQSRSTLLSSQRTCIFAELHIQKHIILQK*VF LRSFTTGMSTFVSDRC*RPRCAVPKSSAEAHVA QAGAPAVSVRGGLVCFPLVYQSTFLRGRLWGSH ETWTRSLSRTVCVHELRAQHRHAWNPRRLLLPPR EPISGERRDCRAAWSFLQPPTQGPRHVAWAAIL PSSHWHPGKGALLFLGGLLCLGDT*CKVSVNLF HI*PTKQISL**KSFL*VL

Frame 2

GAAE*GPWWGAAG*GPWWGTAG*GP*ALQGCSQ VKALVGCSRVRALSPGGVQPGEGPGGCSRMWAL SLQCWPEQPDAAGSPAGTEKVLQAQECGHLHVV NPDWLWSCLERWDKVEEQLFPLRDDHTKAQRENS PAAFPDREGVPPTALFHPMPVLPKAQPGPEVRI YDSNTGKLIRTGARGPPAPSSSLPIRQEPSSFR GHKRKLNEEDAASESSRESSNEDEGSSSEADEMA KALEAELNDLM*ARAAGRD*SLTDLQQHSDVPG PALSLGPRCFLPKGHVYLQSSTYRNTLFCRNRC F*EVLLQECLLL*VTGVKGPGVLCQRAQQRLTWP RLVRPLSR*GAGWCVFPLCTRAHSLGDGFGGPT RHGLGV*AGQCACTSSEPSTDMPGTPAACCSLL GNPFPGNAVTVGQPGASCSLLRRVHATWPGLPSC RPPTGILARGRCFSWAAFYVLETPDVKFL*IYF ISDPPNRFLFNKNPFCKFS

Sequence CTDP1.aAug05

GGAAGTCGGCGCGGGCTAGGCGACGGGTGGAAGCCGGTACCGAGAGGAACTACAGCGTCGCCGCCTGGGTTGTGTCGCCGCGGTAGGCGCTGCGCTCTGA GCGCAGCGCAGGCCCCGTACCGACCGCCCGCCCGCCCTCTGTCCGCGATGGAGGTGCCGGCCGCGGGTCGCGTTCCTGCCGAGGGCGCCCCGACGGCGGC TGTGGCCGAGGTGCGCTGCCCGGGGCCCGCGCCGCTGCGCCTGCTGGAGTGGAGGGTGGCGGCGGGCGCGGCCGTGCGCATCGGCTCGGTGCTGGCCGTG TTCGAGGCCGCCGCCTCCGCGCAGTCCTCCGGGGCCTCTCAGTCCCGTGTAGCCTCCGGGGGCTGCGTGCGCCCCGCGCGGCCGGAACGCAGGCTGAGGT CGGAGCGCGCGGGCGTGGTGCGGGAGCTGTGCGCGCAGCCGGGCCAGGTGGTCGCCCCAGGAGCGGTTCTGGTGAGGTTGGAAGGATGCAGCCACCCGGT TGTCATGAAAGGCCTGTGTGCTGAATGTGGCCAAGACCTCACCCAGTTGCAGAGTAAGAACGGGAAGCAGCAGGTGCCGCTGTCCACGGCGACCGTGTCC ATGGTGCACAGCGTGCCGGAGTTGATGGTGAGCTCCGAGCAAGCTGAACAGCTGGGAAGAGAAGACCAGCAGCGACTGCACCGAAACCGGAAGCTGGTGC TCATGGTGGACTTGGACCAGACGTTGATTCACACAACCGAGCAGCACTGTCAGCAGATGTCGAATAAAGGCATCTTTCACTTCCAGCTGGGCCGGGGTGA GCCCATGCTGCACACGCGCCTGCGTCCACACTGCAAGGACTTCCTGGAGAAGATCGCCAAGCTGTACGAGCTGCACGTCTTCACCTTCGGCAGCCGGCTG TACGCACACACCATCGCAGGCTTTTTAGACCCCGAGAAGAAGCTTTTTTCTCACCGAATATTATCAAGGGATGAATGTATTGACCCATTTTCTAAAACGG GAAACCTTAGAAATCTCTTTCCTTGTGGAGACTCAATGGTTTGCATTATTGATGATCGAGAAGATGTCTGGAAGTTTGCCCCCAATCTGATAACTGTGAA GAAATATGTATACTTCCAGGGCACGGGTGATATGAATGCGCCCCCTGGGTCCCGAGAATCTCAGACGAGAAAGAAAGTAAATCATTCTCGAGGCACTGAG GTCTCAGAGCCATCTCCGCCCGTGAGAGACCCTGAGGGGGTAACGCAGGCCCCTGGAGTGGAGCCCAGCAATGGCCTGGAGAAGCCTGCACGGGAGCTGA ACGGCAGCGAGGCCGCCACCCCGCGGGACTCACCCCGCCCCGGGAAGCCAGACGAGAGGGACATCTGGCCCCCTGCCCAGGCCCCCACCAGCAGCCAAGA GCTGGCAGGCGCTCCTGAGCCCCAGGGATCCTGTGCGCAGGGTGGCCGGGTGGCACCGGGACAGCGGCCTGCCCAGGGTGCCACGGGCACTGACCTGGAC TTTGACTTATCCAGCGACAGCGAGAGCAGCAGTGAGTCCGAGGGCACGAAGTCCTCCTCCTCCGCCTCTGATGGCGAAAGCGAGGGGAAAAGAGGCCGGC AGAAGCCGAAGGCTGCCCCAGAGGGAGCCGGGGCGCTGGCACAGGGCAGTTCCCTGGAGCCGGGGCGGCCTGCAGCACCGAGTCTCCCCGGAGAGGCCGA GCCTGGCGCGCATGCCCCGGACAAGGAGCCTGAGCTGGGTGGGCAGGAGGAGGGCGAGCGGGATGGCCTCTGCGGCCTGGGCAACGGCTGTGCCGACAGG AAGGAGGCGGAGACCGAGTCACAGAACAGCGAGCTGTCGGGGGTCACTGCGGGTGAGTCCCTGGACCAGAGCATGGAGGAGGAGGAGGAGGAGGACACGG ATGAGGATGACCACCTCATCTACCTGGAGGAGATCCTGGTCCGTGTACACACTGACTACTATGCCAAGTATGACCGCTACCTCAACAAGGAGATCGAGGA GGCGCCGGACATCCGCAAGATCGTGCCGGAGCTCAAGAGCAAGGTGCTGGCAGACGTGGCCATAATTTTCAGTGGGCTACACCCGACAAACTTCCCGATA GAGAAGACGCGGGAGCATTACCACGCCACGGCGCTGGGAGCGAAGATCCTCACTCGGCTGGTGCTGAGCCCCGACGCCCCTGACAGGGCCACGCACCTGA TCGCCGCGCGAGCTGGCACAGAGAAGGTGCTGCAGGCACAGGAGTGCGGACACCTGCACGTGGTCAACCCTGACTGGCTGTGGAGCTGCCTGGAGCGCTG GGACAAGGTGGAGGAGCAGCTCTTCCCGCTCAGGGACGATCACACCAAGGCACAGAGGGAGAACAGCCCTGCGGCCTTTCCCGACCGGGAGGGTGTGCCC CCCACCGCCTTGTTCCACCCGATGCCGGTTCTTCCCAAGGCCCAGCCTGGCCCCGAGGTTCGGATCTACGACTCCAACACGGGGAAGCTCATCAGGACGG GCGCCCGGGGGCCCCCAGCACCCTCCAGCTCCCTACCCATCCGCCAGGAGCCCTCTTCCTTCAGAGCGGTTCCGCCACCCCAGCCGCAGATGTTTGGTGA AGAGCTGCCTGACGCTCAGGACGGAGAGCAGCCTGGCCCTTCTAGAAGAAAGCGACAGCCCAGTATGTCTGAGACAATGCCGCTGTACACTCTTTGTAAG GAGGATTTAGAGAGTATGGACAAAGAGGTGGACGACATCCTTGGAGAAGGCAGCGACGACAGCGACAGCGAGAAGAGGAGGCCTGAGGAGCAGGAGGAGG AGCCCCAGCCCCGGAAGCCAGGGACCCGCAGGGAGCGGACGCTCGGGGCACCTGCGTCCAGCGAGAGGAGCGCGGCAGGGGGCCGGGGGCCCAGAGGCCA CAAGAGGAAGCTGAATGAAGAGGACGCCGCCAGCGAGTCCAGCAGGGAGTCCAGCAACGAGGATGAGGGCAGCAGCTCCGAGGCCGACGAGATGGCCAAG GCGCTGGAGGCGGAGCTCAACGACCTCATGTGAGCGCGGGCAGCGGGCAGGGACTGAAGCCTGACCGACCTCCAGCAGCACTCGGACGTCCCCGGACCAG CCCTCAGTCTCGGTCCACGCTGCTTTCTTCCCAAAGGACATGTATATTTGCAGAGCTCCACATACAGAAACACATTATTTTGCAGAAATAGGTGTTTTTA AGAAGTTTTACTACAGGAATGTCTACTTTTGTAAGTGACAGGTGTTAAAGGCCCAGGTGTGCTGTGCCAAAGAGCTCAGCAGAGGCTCACGTGGCCCAGG CTGGTGCGCCCGCTGTCTCGGTAAGGGGCGGGTTGGTGTGTTTTCCCCTTGTGTACCAGAGCACATTCCTTAGGGGACGGCTTTGGGGGTCCCACGAGAC ATGGACTAGGAGTTTAAGCAGGACAGTGTGCGTGCACGAGCTCCGAGCCCAGCACAGACATGCCTGGAACCCCCGCCGCCTGCTGCTCCCTCCTAGGGAA CCCATTTCCGGGGAACGCCGTGACTGTCGGGCAGCCTGGAGCTTCCTGCAGCCTCCTACGCAGGGTCCACGCCACGTGGCCTGGGCTGCCATCCTGCCGT CCTCCCACTGGCATCCTGGCAAGGGGGCGTTGCTTTTCCTGGGCGGCCTTTTATGTCTTGGAGACACCTGATGTAAAGTTTCTGTAAATCTATTTCATAT CTGACCCACCAAACAGATTTCTCTTTAATAAAAATCCTTTTTGTAAGTTCTCT

CTDP1.F7 (forward primer)
CTDP1.R7 (reverse primer)
Multiple exon skipping

Frame 0

GSRRGLGDGWKPVPRGTTASPPGLCRRGRRCAL SAAQAPYRPPARPLSAMEVPAAGRVPAEGAPTAA VAEVRCPGPAPLRLLEWRVAAGAAVRIGSVLAV FEAAASAQSSGASQSRVASGGCVRPARPERRLR SERAGVVRELCAQPGQVVAPGAVLVRLEGCSHPV VMKGLCAECGQDLTQLQSKNGKQQVPLSTATVS MVHSVPELMVSSEQAEQLGREDQQRLHRNRKLV LMVDLDQTLIHTTEQHCQQMSNKGIFHFQLGRGE PMLHTRLRPHCKDFLEKIAKLYELHVFTFGSRL YAHTIAGFLDPEKKLFSHRILSRDECIDPFSKT GNLRNLFPCGDSMVCIIDDREDVWKFAPNLITVK KYVYFQGTGDMNAPPGSRESQTRKKVNHSRGTE VSEPSPPVRDPEGVTQAPGVEPSNGLEKPAREL NGSEAATPRDSPRPGKPDERDIWPPAQAPTSSQE LAGAPEPQGSCAQGGRVAPGQRPAQGATGTDLD FDLSSDSESSSESEGTKSSSSASDGESEGKRGR QKPKAAPEGAGALAQGSSLEPGRPAAPSLPGEAE PGAHAPDKEPELGGQEEGERDGLCGLGNGCADR KEAETESQNSELSGVTAGESLDQSMEEEEEEDT DEDDHLIYLEEILVRVHTDYYAKYDRYLNKEIEE APDIRKIVPELKSKVLADVAIIFSGLHPTNFPI EKTREHYHATALGAKILTRLVLSPDAPDRATHL IAARAGTEKVLQAQECGHLHVVNPDWLWSCLERW DKVEEQLFPLRDDHTKAQRENSPAAFPDREGVP PTALFHPMPVLPKAQPGPEVRIYDSNTGKLIRT GARGPPAPSSSLPIRQEPSSFRAVPPPQPQMFGE ELPDAQDGEQPGPSRRKRQPSMSETMPLYTLCK EDLESMDKEVDDILGEGSDDSDSEKRRPEEQEE EPQPRKPGTRRERTLGAPASSERSAAGGRGPRGH KRKLNEEDAASESSRESSNEDEGSSSEADEMAK ALEAELNDLM*ARAAGRD*SLTDLQQHSDVPGP ALSLGPRCFLPKGHVYLQSSTYRNTLFCRNRCF* EVLLQECLLL*VTGVKGPGVLCQRAQQRLTWPR LVRPLSR*GAGWCVFPLCTRAHSLGDGFGGPTR HGLGV*AGQCACTSSEPSTDMPGTPAACCSLLGN PFPGNAVTVGQPGASCSLLRRVHATWPGLPSCR PPTGILARGRCFSWAAFYVLETPDVKFL*IYFI SDPPNRFLFNKNPFCKFS

Frame 1

EVGAG*ATGGSRYREELQRRRLGCVAAVGAAL* AQRRPRTDRPPALCPRWRCRPRVAFLPRAPRRR LWPRCAARGPRRCACWSGGWRRARPCASARCWPC SRPPPPRSPPGPLSPV*PPGAACAPRGRNAG*G RSARAWCGSCARSRARWSPQERFW*GWKDAATR LS*KACVLNVAKTSPSCRVRTGSSRCRCPRRPCP WCTACRS*W*APSKLNSWEEKTSSDCTETGSWC SWWTWTRR*FTQPSSTVSRCRIKASFTSSWAGV SPCCTRACVHTARTSWRRSPSCTSCTSSPSAAGC THTPSQAF*TPRRSFFLTEYYQGMNVLTHFLKR ETLEISFLVETQWFALLMIEKMSGSLPPI**L* RNMYTSRARVI*MRPLGPENLRRERK*IILEALR SQSHLRP*ETLRG*RRPLEWSPAMAWRSLHGS* TAARPPPRGTHPAPGSQTRGTSGPLPRPPPAAK SWQALLSPRDPVRRVAGWHRDSGLPRVPRALTWT LTYPATARAAVSPRARSPPPPPLMAKARGKEAG RSRRLPQREPGRWHRAVPWSRGGLQHRVSPERP SLARMPRTRSLSWVGRRRASGMASAAWATAVPTG RRRRPSHRTASCRGSLRVSPWTRAWRRRRRRTR MRMTTSSTWRRSWSVYTLTTMPSMTATSTRRSR RRRTSARSCRSSRARCWQTWP*FSVGYTRQTSR* RRRGSITTPRRWERRSSLGWC*APTPLTGPRT* SPRELAQRRCCRHRSADTCTWSTLTGCGAAWSA GTRWRSSSSRSGTITPRHRGRTALRPFPTGRVCP PPPCSTRCRFFPRPSLAPRFGSTTPTRGSSSGR APGGPQHPPAPYPSARSPLPSERFRHPSRRCLV KSCLTLRTESSLALLEESDSPVCLRQCRCTLFVR RI*RVWTKRWTTSLEKAATTATARRGGLRSRRR SPSPGSQGPAGSGRSGHLRPARGARQGAGGPEA TRGS*MKRTPPASPAGSPATRMRAAAPRPTRWPR RWRRSSTTSCERGQRAGTEA*PTSSSTRTSPDQ PSVSVHAAFFPKDMYICRAPHTETHYFAEIGVF KKFYYRNVYFCK*QVLKAQVCCAKELSRGSRGPG WCARCLGKGRVGVFSPCVPEHIP*GTALGVPRD MD*EFKQDSVRARAPSPAQTCLEPPPPAAPS*G THFRGTP*LSGSLELPAASYAGSTPRGLGCHPAV LPLASWQGGVAFPGRPFMSWRHLM*SFCKSISY LTHQTDFSLIKILFVSS

Frame 2

KSARARRRVEAGTERNYSVAAWVVSPR*ALRSE RSAGPVPTARPPSVRDGGAGRGSRSCRGRPDGG CGRGALPGARAAAPAGVEGGGGRGRAHRLGAGR VRGRRLRAVLRGLSVPCSLRGLRAPRAAGTQAEV GARGRGAGAVRAAGPGGRPRSGSGEVGRMQPPG CHERPVC*MWPRPHPVAE*EREAAGAAVHGDRV HGAQRAGVDGELRAS*TAGKRRPAATAPKPEAGA HGGLGPDVDSHNRAALSADVE*RHLSLPAGPG* AHAAHAPASTLQGLPGEDRQAVRAARLHLRQPA VRTHHRRLFRPREEAFFSPNIIKG*MY*PIF*NG KP*KSLSLWRLNGLHY**SRRCLEVCPQSDNCE EICILPGHG*YECAPWVPRISDEKESKSFSRH* GLRAISARERP*GGNAGPWSGAQQWPGEACTGAE RQRGRHPAGLTPPREARREGHLAPCPGPHQQPR AGRRS*APGILCAGWPGGTGTAACPGCHGH*PG L*LIQRQREQQ*VRGHEVLLLRL*WRKRGEKRPA EAEGCPRGSRGAGTGQFPGAGAACSTESPRRGR AWRACPGQGA*AGWAGGGRAGWPLRPGQRLCRQ EGGGDRVTEQRAVGGHCG*VPGPEHGGGGGGGHG *G*PPHLPGGDPGPCTH*LLCQV*PLPQQGDRG GAGHPQDRAGAQEQGAGRRGHNFQWATPDKLPD REDAGALPRHGAGSEDPHSAGAEPRRP*QGHAPD RRASWHREGAAGTGVRTPARGQP*LAVELPGAL GQGGGAALPAQGRSHQGTEGEQPCGLSRPGGCA PHRLVPPDAGSSQGPAWPRGSDLRLQHGEAHQDG RPGAPSTLQLPTHPPGALFLQSGSATPAADVW* RAA*RSGRRAAWPF*KKATAQYV*DNAAVHSL* GGFREYGQRGGRHPWRRQRRQRQREEEA*GAGGG APAPEARDPQGADARGTCVQREERGRGPGAQRP QEEAE*RGRRQRVQQGVQQRG*GQQLRGRRDGQ GAGGGAQRPHVSAGSGQGLKPDRPPAALGRPRTS PQSRSTLLSSQRTCIFAELHIQKHIILQK*VFL RSFTTGMSTFVSDRC*RPRCAVPKSSAEAHVAQ AGAPAVSVRGGLVCFPLVYQSTFLRGRLWGSHET WTRSLSRTVCVHELRAQHRHAWNPRRLLLPPRE PISGERRDCRAAWSFLQPPTQGPRHVAWAAILP SSHWHPGKGALLFLGGLLCLGDT*CKVSVNLFHI *PTKQISL**KSFL*VL