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Sequences

Sequence BCAS1.bAug05

GTATTCAGCCAGCAGGCTCTGCACAAGGAAGCAAAGTGCAGGGAGCCAGGCTCCACCGACAGCCAGGCACTGGGCAGCACGCACTGGAGACCCAGGACCC
TGTGCAGGAGCAGCTCCGGGTGACACGAGGGGACTGAAGATACTCCCACAGGGGCTCAGCAGGAGCAATGGGTAACCAAATGAGTGTTCCCCAAAGAGTT
GAAGACCAAGAGAATGAACCAGAAGCAGAGACTTACCAGGACAACGCGTCTGCTCTGAACGGGGTTCCAGTGGTGGTGTCGACCCACACAGTTCAGCACT
TAGAGGAAGTCGACTTGGGAATAAGTGTCAAGACGGATAATGTGGCCACTTCTTCCCCCGAGACAACGGAGATAAGTGCTGTTGCGGATGCCAACGGAAA
GAATCTTGGGAAAGAGGCCAAACCCGAGGCACCAGCTGCTAAATCTCGTTTTTTCTTGATGCTCTCTCGGCCTGTACCAGGACGTACCGGAGACCAAGCC
GCAGATTCATCCCTTGGATCAGTGAAGCTTGATGTCAGCTCCAATAAAGCTCCAGCGAACAAAGACCCAAGTGAGAGCTGGACACTTCCGGTGGCAGCTG
GACCGGGGCAGGACACAGATAAAACCCCAGGGCACGCCCCGGCCCAAGACAAGGTCCTCTCTGCCGCCAGGGATCCCACGCTTCTCCCACCTGAGACAGG
GGGAGCAGGAGGAGAAGCTCCCTCCAAGCCCAAGGACTCCAGCTTTTTTGACAAATTCTTCAAGCTGGACAAGGGACAGGAAAAGGTGCCAGGTGACAGC
CAACAGGAAGCCAAGAGGGCAGAGCATCAAGACAAGGTGGATGAGGTTCCTGGCTTATCAGGGCAGTCCGATGATGTCCCTGCAGGGAAGGACATAGTTG
ACGGCAAGGAAAAAGAAGGACAAGAACTTGGAACTGCGGATTGCTCTGTCCCTGGGGACCCAGAAGGACTGGAGACTGCAAAGGACGATTCCCAGGCAGC
AGCTATAGCAGAGAATAATAATTCCATCATGAGTTTCTTTAAAACTCTGGTTTCACCTAACAAAGCTGAAACAAAAAAGGACCCAGAAGACACGGGTGCT
GAAAAGTCACCCACCACTTCAGCTGACCTTAAGTCAGACAAAGCCAACTTTACATCCCAGGAGACCCAAGGGGCTGGCAAGAATTCCAAAGGATGCAACC
CATCGGGGCACACACAGTCCGTGACAACCCCTGAACCTGCGAAGGAAGGCACCAAGGAGAAATCAGGACCCACCTCTCTGCCTCTGGGCAAACTGTTTTG
GAAAAAGTCAGTTAAAGAGGACTCAGTCCCCACAGGTGCGGAGGAGAATACATCAGACTCCACAGAAAAGACTATCACACCGCCAGAGCCTGAACCAACA
GGAGCACCACAGAAGGGTAAAGAGGGCTCCTCGAAGGACAAGAAGTCAGCAGCCGAGATGAACAAGCAGAAGAGCAACAAGCAGGAAGCCAAAGAACCAG
CCCAGTGCACAGAGCAGGCCACGGTGGACACGAACTCACTGCAGAATGGGGACAAGCTCCAAAAGAGACCTGAGAAGCGGCAGCAGTCCCTTGGGGGCTT
CTTTAAAGGCCTGGGACCAAAGCGGATGTTGGATGCTCAAGTGCAAACAGACCCAGTATCCATCGGACCAGTTGGCAAATCCAAGTAAACAAATCAGCAC
GGTTCCCACCAGGTTCTCCTGCCACCAAGATGTGTTCTCCTTACTCCATCTCCTCCCCAAACACGCTCCATGTATATATTCTTCTGATGGCCAGCAAATG
AAATTCTGCCTAGAAATTAAGCCCGAGCTGTTGTATATTGAGGTGTATTATTTACGTCTCTGGTCCAGTCTTTTCTGGCAAATAACAGTAAAGATGGTTT
AGCAGGTCACCTAGTTGGGTCAGAAGAGTCGATGATCACCAAGCAGGAAAGGGAGGGAATAGAGGAATGTGTTCGGGTTAAGTGATGAAAATGGCAGTGG
TGGCCGGGCGTGGTGGCTCTCGCCTGTAATCTCAGCACTTTGGGAGGCCGAGGCAGGTGGATCACCTGAGGTCAGGAGTTCAAGACTAGCCTGGCCAACA
TCATGAAACCCCGTCTCTACTAAAAATACAAAAATTAGCCAGGCATGGTGGCACACACCTGTAGTCCCAGCTACTCGGGAGCCCAACGCACGAGAACCGC
TTGTACCCAGGAGGTGGAGGTTGCAGTGAGCCGAAGTTGCACCATTGCACTCCACCCTGGGCGACAGAGCAAGATTCTATCAAAAAAAAAAAAAGGCAGT
GGCAAGTAAGTTATAGAAGAGAAATGCTGCTAGAAGGAATTAAGCGTTGTAGTAAATGCGTGCTTATCCTCTAAGCTTGAAGAAGGGAGACGAAAATCCA
TTTGTTTAAATTCACATCTCAAGGAGGGAGAACCCGGGCTGTGTTGGGTGGTTGCCAATTTCCTAGAACGGAATGTGTGGGGTATAGAAAAAGGAATGAA
TAAGCGTTGTTTTTCAAATAGGGTCCTTGTAAGTTATTGATGAGAGGGAAAAGATTGACTGGGGAGGGCTTAAAATGATTTGGGAAAACAATTGCTTTTG
AGGCTCAGTGACAACGGCAAAGATTACAACTTAAAAAAAAAAAATAAATAAAAAATAAAGGAAGTTGCACGGTTATTTTGCAACACAAGGGGGCGGCAAG
GTCCCCATTTTTATCCTGTAATACTGTATCCCTAACAAAGATTTGGTCTCTGCTATCTTACATTATTAATGTTTCTCAGATGGCTGAGGGGCTCGCTTCA
TCTGTTCCGTCTGACACTTATCTCAAGTGTGTCTGTCATTCCTAATGTTCTCAGGATGTGCTCTGATAAAACCCTCCCCATAACCTCAGTTAATAAAAAT
TTACAGAAGACTTCTCAAATACCTGAGTTGTTTTTAATACCTGTACAAAGGAGTAAATAGGACCCTGAGTCTATTAAAATGTAATTCAAAGTAGCATATG
ATTGACTGACAGTCATGTAAACTGTATCTTTCTTTTTCTGATTTAATAAAAAATACATTTACTTCTAAAGTATCTTTTAATTTTCAACTTCAAAGCAGTC
CCACTCTATATCTGAGATGACTCTAACTTCTACATTATAAAATCCATACTCTTTCTCCATTATCTTCTTTGGAAGATCATTCTCTCCCAGATCTTCCCGG
ATTTCCTTGTATATGGGCACACACACACACAAATGTGTGCAGTTGTATGTTTGCATGTACACACACATGCATGTATAGAATAGTGCTGTCTTAGGCCAGG
TTGCTTGGAGCAGAGCCTGAGATGGGGATTTGGACGCATAGGATATACTGAGAGTGGGCTCCGAGGGAAAGGGAGTAAGAGAAAAAGAAGAGGGCAAGAA
AAGAGTTGGGCAAGGGTTGGTTTCAACTGGAGCATGAATTGCACCACCCAGATAGTTTGACCTTGAGTCAAGGGAGCCAGCCTTTGAACCCTGGTAGGTG
AATTCTGGGCTGCCCTGGGAGGTGGGGGG
  • BCAS1.F2 (forward primer)
  • BCAS1.R1 (reverse primer)
  • Single exon skipping

Frame 0

VFSQQALHKEAKCREPGSTDSQALGSTHWRPRT
LCRSSSG*HEGTEDTPTGAQQEQWVTK*VFPKEL
KTKRMNQKQRLTRTTRLL*TGFQWWCRPTQFST
*RKSTWE*VSRRIMWPLLPPRQRR*VLLRMPTE
RILGKRPNPRHQLLNLVFS*CSLGLYQDVPETKP
QIHPLDQ*SLMSAPIKLQRTKTQVRAGHFRWQL
DRGRTQIKPQGTPRPKTRSSLPPGIPRFSHLRQ
GEQEEKLPPSPRTPAFLTNSSSWTRDRKRCQVTA
NRKPRGQSIKTRWMRFLAYQGSPMMSLQGRT*L
TARKKKDKNLELRIALSLGTQKDWRLQRTIPRQ
QL*QRIIIPS*VSLKLWFHLTKLKQKRTQKTRVL
KSHPPLQLTLSQTKPTLHPRRPKGLARIPKDAT
HRGTHSP*QPLNLRRKAPRRNQDPPLCLWANCF
GKSQLKRTQSPQVRRRIHQTPQKRLSHRQSLNQQ
EHHRRVKRAPRRTRSQQPR*TSRRATSRKPKNQ
PSAQSRPRWTRTHCRMGTSSKRDLRSGSSPLGA
SLKAWDQSGCWMLKCKQTQYPSDQLANPSKQIST
VPTRFSCHQDVFSLLHLLPKHAPCIYSSDGQQM
KFCLEIKPELLYIEVYYLRLWSSLFWQITVKMV
*QVT*LGQKSR*SPSRKGRE*RNVFGLSDENGSG
GRAWWLSPVISALWEAEAGGSPEVRSSRLAWPT
S*NPVSTKNTKISQAWWHTPVVPATREPNAREP
LVPRRWRLQ*AEVAPLHSTLGDRARFYQKKKKAV
ASKL*KRNAARRN*AL**MRAYPLSLKKGDENP
FV*IHISRRENPGCVGWLPIS*NGMCGV*KKE*
ISVVFQIGSL*VIDEREKIDWGGLKMIWENNCF*
GSVTTAKITT*KKKINKK*RKLHGYFATQGGGK
VPIFIL*YCIPNKDLVSAILHY*CFSDG*GARF
ICSV*HLSQVCLSFLMFSGCALIKPSP*PQLIKI
YRRLLKYLSCF*YLYKGVNRTLSLLKCNSK*HM
ID*QSCKLYLSFSDLIKNTFTSKVSFNFQLQSS
PTLYLR*L*LLHYKIHTLSPLSSLEDHSLPDLPG
FPCIWAHTHTNVCSCMFACTHTCMYRIVLS*AR
LLGAEPEMGIWTHRIY*EWAPRERE*EKKKRAR
KELGKGWFQLEHELHHPDSLTLSQGSQPLNPGR*
ILGCPGRWG

Frame 1

YSASRLCTRKQSAGSQAPPTARHWAARTGDPGP
CAGAAPGDTRGLKILPQGLSRSNG*PNECSPKS
*RPRE*TRSRDLPGQRVCSERGSSGGVDPHSSAL
RGSRLGNKCQDG*CGHFFPRDNGDKCCCGCQRK
ESWERGQTRGTSC*ISFFLDALSACTRTYRRPS
RRFIPWISEA*CQLQ*SSSEQRPK*ELDTSGGSW
TGAGHR*NPRARPGPRQGPLCRQGSHASPT*DR
GSRRRSSLQAQGLQLF*QILQAGQGTGKGAR*Q
PTGSQEGRASRQGG*GSWLIRAVR*CPCREGHS*
RQGKRRTRTWNCGLLCPWGPRRTGDCKGRFPGS
SYSRE**FHHEFL*NSGFT*QS*NKKGPRRHGC
*KVTHHFS*P*VRQSQLYIPGDPRGWQEFQRMQP
IGAHTVRDNP*TCEGRHQGEIRTHLSASGQTVL
EKVS*RGLSPHRCGGEYIRLHRKDYHTARA*TN
RSTTEG*RGLLEGQEVSSRDEQAEEQQAGSQRTS
PVHRAGHGGHELTAEWGQAPKET*EAAAVPWGL
L*RPGTKADVGCSSANRPSIHRTSWQIQVNKSA
RFPPGSPATKMCSPYSISSPNTLHVYILLMASK*
NSA*KLSPSCCILRCIIYVSGPVFSGK*Q*RWF
SRSPSWVRRVDDHQAGKGGNRGMCSG*VMKMAV
VAGRGGSRL*SQHFGRPRQVDHLRSGVQD*PGQH
HETPSLLKIQKLARHGGTHL*SQLLGSPTHENR
LYPGGGGCSEPKLHHCTPPWATEQDSIKKKKRQ
WQVSYRREMLLEGIKRCSKCVLIL*A*RRETKIH
LFKFTSQGGRTRAVLGGCQFPRTECVGYRKRNE
*ALFFK*GPCKLLMRGKRLTGEGLK*FGKTIAF
EAQ*QRQRLQLKKKK*IKNKGSCTVILQHKGAAR
SPFLSCNTVSLTKIWSLLSYIINVSQMAEGLAS
SVPSDTYLKCVCHS*CSQDVL**NPPHNLS**K
FTEDFSNT*VVFNTCTKE*IGP*VY*NVIQSSI*
LTDSHVNCIFLFLI**KIHLLLKYLLIFNFKAV
PLYI*DDSNFYIIKSILFLHYLLWKIILSQIFP
DFLVYGHTHTQMCAVVCLHVHTHACIE*CCLRPG
CLEQSLRWGFGRIGYTESGLRGKGSKRKRRGQE
KSWARVGFNWSMNCTTQIV*P*VKGASL*TLVG
EFWAALGGGG

Frame 2

IQPAGSAQGSKVQGARLHRQPGTGQHALETQDP
VQEQLRVTRGD*RYSHRGSAGAMGNQMSVPQRV
EDQENEPEAETYQDNASALNGVPVVVSTHTVQH
LEEVDLGISVKTDNVATSSPETTEISAVADANGK
NLGKEAKPEAPAAKSRFFLMLSRPVPGRTGDQA
ADSSLGSVKLDVSSNKAPANKDPSESWTLPVAA
GPGQDTDKTPGHAPAQDKVLSAARDPTLLPPETG
GAGGEAPSKPKDSSFFDKFFKLDKGQEKVPGDS
QQEAKRAEHQDKVDEVPGLSGQSDDVPAGKDIV
DGKEKEGQELGTADCSVPGDPEGLETAKDDSQAA
AIAENNNSIMSFFKTLVSPNKAETKKDPEDTGA
EKSPTTSADLKSDKANFTSQETQGAGKNSKGCN
PSGHTQSVTTPEPAKEGTKEKSGPTSLPLGKLFW
KKSVKEDSVPTGAEENTSDSTEKTITPPEPEPT
GAPQKGKEGSSKDKKSAAEMNKQKSNKQEAKEP
AQCTEQATVDTNSLQNGDKLQKRPEKRQQSLGGF
FKGLGPKRMLDAQVQTDPVSIGPVGKSK*TNQH
GSHQVLLPPRCVLLTPSPPQTRSMYIFF*WPAN
EILPRN*ARAVVY*GVLFTSLVQSFLANNSKDGL
AGHLVGSEESMITKQEREGIEECVRVK**KWQW
WPGVVALACNLSTLGGRGRWIT*GQEFKTSLAN
IMKPRLY*KYKN*PGMVAHTCSPSYSGAQRTRTA
CTQEVEVAVSRSCTIALHPGRQSKILSKKKKGS
GK*VIEEKCC*KELSVVVNACLSSKLEEGRRKS
ICLNSHLKEGEPGLCWVVANFLERNVWGIEKGMN
KRCFSNRVLVSY**EGKD*LGRA*NDLGKQLLL
RLSDNGKDYNLKKKNK*KIKEVARLFCNTRGRQ
GPHFYPVILYP*QRFGLCYLTLLMFLRWLRGSLH
LFRLTLISSVSVIPNVLRMCSDKTLPITSVNKN
LQKTSQIPELFLIPVQRSK*DPESIKM*FKVAY
D*LTVM*TVSFFF*FNKKYIYF*SIF*FSTSKQS
HSISEMTLTSTL*NPYSFSIIFFGRSFSPRSSR
ISLYMGTHTHKCVQLYVCMYTHMHV*NSAVLGQ
VAWSRA*DGDLDA*DILRVGSEGKGVREKEEGKK
RVGQGLVSTGA*IAPPR*FDLESREPAFEPW*V
NSGLPWEVG

Sequence BCAS1.eAug05

AGAATAATAATTCCATCATGAGTTTCTTTAAAACTCTGGTTTCACCTAACAAAGCTGAAACAAAAAAGGACCCAGAAGACACGGGTGCTGAAAAGTCACC
CACCACTTCAGCTGACCTTAAGTCAGACAAAGCCAACTTTACATCCCAGGAGACCCAAGGGGCTGGCAAGAATTCCAAAGGATGCAACCCATCGGGGCAC
ACACAGTCCGTGACAACCCCTGAACCTGCGAAGGAAGGCACCAAGGAGAAATCAGGACCCACCTCTCTGCCTCTGGGCAAACTGTTTTGGAAAAAGTCAG
TTAAAGAGGACTCAGTCCCCACAGGTGCGGAGGAGAATTCAGTGAAAGGGGATGGAGGGATCACCCACTCAGAAGAAATAAATGGGAAAGACTCCAGCTG
CCAAACATCAGACTCCACAGAAAAGACTATCACACCGCCAGAGCCTGAACCAACAGGAGCACCACAGAAGGGTAAAGAGGGCTCCTCGAAGGACAAGAAG
TCAGCAGCCGAGATGAACAAGCAGAAGAGCAACAAGCAGGAAGCCAAAGAACCAGCCCAGTGCACAGAGCAGGCCACGGTGGACACGAACTCACTGCAGA
ATGGGGACAAGCTCCAAAAGAGACCTGAGAAGCGGCAGCAGTCCCTTGGGGGCTTCTTTAAAGGCCTGGGACCAAAGCGGATGTTGGATGCTCAAGTGCA
AACAGACCCAGTATCCATCGGACCAGTTGGCAAATCCAAGTAAACAAATCAGCACGGTTCCCACCAGGTTCTCCTGCCACCAAGATGTGTTCTCCTTACT
CCATCTCCTCCCCAAACACGCTCCATGTATATATTCTTCTGATGGCCAGCAAATGAAATTCTGCCTAGAAATTAAGCCCGAGCTGTTGTATATTGAGGTG
TATTATTTACGTCTCTGGTCCAGTCTTTTCTGGCAAATAACAGTAAAGATGGTTTAGCAGGTCACCTAGTTGGGTCAGAAGAGTCGATGATCACCAAGCA
GGAAAGGGAGGGAATAGAGGAATGTGTTCGGGTTAAGTGATGAAAATGGCAGTGGTGGCCGGGCGTGGTGGCTCTCGCCTGTAATCTCAGCACTTTGGGA
GGCCGAGGCAGGTGGATCACCTGAGGTCAGGAGTTCAAGACTAGCCTGGCCAACATCATGAAACCCCGTCTCTACTAAAAATACAAAAATTAGCCAGGCA
TGGTGGCACACACCTGTAGTCCCAGCTACTCGGGAGCCCAACGCACGAGAACCGCTTGTACCCAGGAGGTGGAGGTTGCAGTGAGCCGAAGTTGCACCAT
TGCACTCCACCCTGGGCGACAGAGCAAGATTCTATCAAAAAAAAAAAAAGGCAGTGGCAAGTAAGTTATAGAAGAGAAATGCTGCTAGAAGGAATTAAGC
GTTGTAGTAAATGCGTGCTTATCCTCTAAGCTTGAAGAAGGGAGACGAAAATCCATTTGTTTAAATTCACATCTCAAGGAGGGAGAACCCGGGCTGTGTT
GGGTGGTTGCCAATTTCCTAGAACGGAATGTGTGGGGTATAGAAAAAGGAATGAATAAGCGTTGTTTTTCAAATAGGGTCCTTGTAAGTTATTGATGAGA
GGGAAAAGATTGACTGGGGAGGGCTTAAAATGATTTGGGAAAACAATTGCTTTTGAGGCTCAGTGACAACGGCAAAGATTACAACTTAAAAAAAAAAAAT
AAATAAAAAATAAAGGAAGTTGCACGGTTATTTTGCAACACAAGGGGGCGGCAAGGTCCCCATTTTTATCCTGTAATACTGTATCCCTAACAAAGATTTG
GTCTCTGCTATCTTACATTATTAATGTTTCTCAGATGGCTGAGGGGCTCGCTTCATCTGTTCCGTCTGACACTTATCTCAAGTGTGTCTGTCATTCCTAA
TGTTCTCAGGATGTGCTCTGATAAAACCCTCCCCATAACCTCAGTTAATAAAAATTTACAGAAGACTTCTCAAATACCTGAGTTGTTTTTAATACCTGTA
CAAAGGAGTAAATAGGACCCTGAGTCTATTAAAATGTAATTCAAAGTAGCATATGATTGACTGACAGTCATGTAAACTGTATCTTTCTTTTTCTGATTTA
ATAAAAAATACATTTACTTCTAAAGTATCTTTTAATTTTCAACTTCAAAGCAGTCCCACTCTATATCTGAGATGACTCTAACTTCTACATTATAAAATCC
ATACTCTTTCTCCATTATCTTCTTTGGAAGATCATTCTCTCCCAGATCTTCCCGGATTTCCTTGTATATGGGCACACACACACACAAATGTGTGCAGTTG
TATGTTTGCATGTACACACACATGCATGTATAGAATAGTGCTGTCTTAGGCCAGGTTGCTTGGAGCAGAGCCTGAGATGGGGATTTGGACGCATAGGATA
TACTGAGAGTGGGCTCCGAGGGAAAGGGAGTAAGAGAAAAAGAAGAGGGCAAGAAAAGAGTTGGGCAAGGGTTGGTTTCAACTGGAGCATGAATTGCACC
ACCCAGATAGTTTGACCTTGAGTCAAGGGAGCCAGCCTTTGAACCCTGGTAGGTGAATTCTGGGCTGCCCTGGGAGGTGGGGGG
  • BCAS1.F2 (forward primer)
  • BCAS1.R1 (reverse primer)
  • Single exon skipping

Frame 0

RIIIPS*VSLKLWFHLTKLKQKRTQKTRVLKSH
PPLQLTLSQTKPTLHPRRPKGLARIPKDATHRGT
HSP*QPLNLRRKAPRRNQDPPLCLWANCFGKSQ
LKRTQSPQVRRRIQ*KGMEGSPTQKK*MGKTPA
AKHQTPQKRLSHRQSLNQQEHHRRVKRAPRRTRS
QQPR*TSRRATSRKPKNQPSAQSRPRWTRTHCR
MGTSSKRDLRSGSSPLGASLKAWDQSGCWMLKC
KQTQYPSDQLANPSKQISTVPTRFSCHQDVFSLL
HLLPKHAPCIYSSDGQQMKFCLEIKPELLYIEV
YYLRLWSSLFWQITVKMV*QVT*LGQKSR*SPS
RKGRE*RNVFGLSDENGSGGRAWWLSPVISALWE
AEAGGSPEVRSSRLAWPTS*NPVSTKNTKISQA
WWHTPVVPATREPNAREPLVPRRWRLQ*AEVAP
LHSTLGDRARFYQKKKKAVASKL*KRNAARRN*A
L**MRAYPLSLKKGDENPFV*IHISRRENPGCV
GWLPIS*NGMCGV*KKE*ISVVFQIGSL*VIDE
REKIDWGGLKMIWENNCF*GSVTTAKITT*KKKI
NKK*RKLHGYFATQGGGKVPIFIL*YCIPNKDL
VSAILHY*CFSDG*GARFICSV*HLSQVCLSFL
MFSGCALIKPSP*PQLIKIYRRLLKYLSCF*YLY
KGVNRTLSLLKCNSK*HMID*QSCKLYLSFSDL
IKNTFTSKVSFNFQLQSSPTLYLR*L*LLHYKI
HTLSPLSSLEDHSLPDLPGFPCIWAHTHTNVCSC
MFACTHTCMYRIVLS*ARLLGAEPEMGIWTHRI
Y*EWAPRERE*EKKKRARKELGKGWFQLEHELH
HPDSLTLSQGSQPLNPGR*ILGCPGRWG

Frame 1

E**FHHEFL*NSGFT*QS*NKKGPRRHGC*KVT
HHFS*P*VRQSQLYIPGDPRGWQEFQRMQPIGA
HTVRDNP*TCEGRHQGEIRTHLSASGQTVLEKVS
*RGLSPHRCGGEFSERGWRDHPLRRNKWERLQL
PNIRLHRKDYHTARA*TNRSTTEG*RGLLEGQE
VSSRDEQAEEQQAGSQRTSPVHRAGHGGHELTAE
WGQAPKET*EAAAVPWGLL*RPGTKADVGCSSA
NRPSIHRTSWQIQVNKSARFPPGSPATKMCSPY
SISSPNTLHVYILLMASK*NSA*KLSPSCCILRC
IIYVSGPVFSGK*Q*RWFSRSPSWVRRVDDHQA
GKGGNRGMCSG*VMKMAVVAGRGGSRL*SQHFG
RPRQVDHLRSGVQD*PGQHHETPSLLKIQKLARH
GGTHL*SQLLGSPTHENRLYPGGGGCSEPKLHH
CTPPWATEQDSIKKKKRQWQVSYRREMLLEGIK
RCSKCVLIL*A*RRETKIHLFKFTSQGGRTRAVL
GGCQFPRTECVGYRKRNE*ALFFK*GPCKLLMR
GKRLTGEGLK*FGKTIAFEAQ*QRQRLQLKKKK
*IKNKGSCTVILQHKGAARSPFLSCNTVSLTKIW
SLLSYIINVSQMAEGLASSVPSDTYLKCVCHS*
CSQDVL**NPPHNLS**KFTEDFSNT*VVFNTC
TKE*IGP*VY*NVIQSSI*LTDSHVNCIFLFLI*
*KIHLLLKYLLIFNFKAVPLYI*DDSNFYIIKS
ILFLHYLLWKIILSQIFPDFLVYGHTHTQMCAV
VCLHVHTHACIE*CCLRPGCLEQSLRWGFGRIGY
TESGLRGKGSKRKRRGQEKSWARVGFNWSMNCT
TQIV*P*VKGASL*TLVGEFWAALGGGG

Frame 2

NNNSIMSFFKTLVSPNKAETKKDPEDTGAEKSP
TTSADLKSDKANFTSQETQGAGKNSKGCNPSGH
TQSVTTPEPAKEGTKEKSGPTSLPLGKLFWKKS
VKEDSVPTGAEENSVKGDGGITHSEEINGKDSSC
QTSDSTEKTITPPEPEPTGAPQKGKEGSSKDKK
SAAEMNKQKSNKQEAKEPAQCTEQATVDTNSLQ
NGDKLQKRPEKRQQSLGGFFKGLGPKRMLDAQVQ
TDPVSIGPVGKSK*TNQHGSHQVLLPPRCVLLT
PSPPQTRSMYIFF*WPANEILPRN*ARAVVY*G
VLFTSLVQSFLANNSKDGLAGHLVGSEESMITKQ
EREGIEECVRVK**KWQWWPGVVALACNLSTLG
GRGRWIT*GQEFKTSLANIMKPRLY*KYKN*PG
MVAHTCSPSYSGAQRTRTACTQEVEVAVSRSCTI
ALHPGRQSKILSKKKKGSGK*VIEEKCC*KELS
VVVNACLSSKLEEGRRKSICLNSHLKEGEPGLC
WVVANFLERNVWGIEKGMNKRCFSNRVLVSY**E
GKD*LGRA*NDLGKQLLLRLSDNGKDYNLKKKN
K*KIKEVARLFCNTRGRQGPHFYPVILYP*QRF
GLCYLTLLMFLRWLRGSLHLFRLTLISSVSVIPN
VLRMCSDKTLPITSVNKNLQKTSQIPELFLIPV
QRSK*DPESIKM*FKVAYD*LTVM*TVSFFF*F
NKKYIYF*SIF*FSTSKQSHSISEMTLTSTL*NP
YSFSIIFFGRSFSPRSSRISLYMGTHTHKCVQL
YVCMYTHMHV*NSAVLGQVAWSRA*DGDLDA*D
ILRVGSEGKGVREKEEGKKRVGQGLVSTGA*IAP
PR*FDLESREPAFEPW*VNSGLPWEVG

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