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Sequences

Sequence ILK.gAug05

ILK.F11 (forward primer)
ILK.R12 (reverse primer)
Alternative acceptor

Frame 0

SPSPGECERTRAPCHPSLLLSPK*GTEPTLGRT PGPLSQSIRSLNLPTSPNSVRG*GLVACSRTSVQ QTLPLRHPLPTLTRLYLASRGHSQGSSRSPELL HRPPLAGDAAQAPYPQHKHFSPVEDKAWGSSSF PGSLHSPQASPIQGTRRRDAAMDDIFTQCREGNA VAVRLWLDNTENDLNQGDDHGFSPLHWACREGR SAVVEMLIMRGARINVMNRGDDTPLHLAASHGH RDIVQKLLQYKADINAVNEHGNVPLHYACFWGQD QVAEDLVANGALVSICNKYGEMPVDKAKAPLRE LLREKMGQNLNRIPYKDTFWKGTTRTRPRESPL WEEGL*KEIILASWGWVRVKLGT*PAHTLRKWNP EQTLWH*LQTA*LPDEAQRESLWRGDPCPSCPS LTKPP*ITCFVPVLSFSSS*WARKWQQHFKPPN PYLSCSYGRAAGRAMTLS*RC*RFETGVQGRAGT SMKSVPGSGFSRIQMCSQC*VPASLHLLLILLS SHTGCRMDPSTMYYMKAPISSWTRARL*SLLWT WQGAWPSYTH*SPSSHDMHSIAVV**LMRT*LPE LAWLMSSSLSNVLVACMHLPG*PPKLCRRSLKT QTDAQQTCGVLQCFCGNW*HGRYPLLTSPIWRL E*R*EHNSIHLCCGSGW*W*K*L*WALAPHIFVR IYSNPVPRASGFSLHDRLKL*GCFFSCIRRWHW KAFGLPSHQVFPLMCVSS*RSA*MKTLQSDPNL T*LCLSLRRCRTSRTGRSLPELQRCRDMVGGMHL PKAAGLWLPPPPPVMVLPQPWGPSPSPIPTTVA PRGAGSELCHLPHGVSQHGRDQPRLSQ*SLL*K

Frame 1

ARVPVSARGPAPPVTPHFS*VPSKERSQPWGGP PVPSPRVYGA*TSPLPPTLFADRV*LPALGHPF SRHYLFVTPCPP*PAFTSRLEDTARDHPAAPNSF TDPH*PGTQLRPPTPNTNTSLL*RIKLGVHPPS LDHSTVLRLPQSRGLGAGTLLWTTFSLSAGRAT QSPFACGWTTRRTTSTRGTIMASPPCTGPAERAA LLWLRC*SCGGHGSM**TVGMTPPCIWQPVMDT VILYRSYCSTRQTSMQ*MNTGMCPCTMPVFGAK IKWQRTWWQMGPLSASVTSMERCLWTKPRHP*ES FSERRWARISTVFHTRTHSGRGPPALGPVSHHC GKKGCKRK*SWPLGAGLG*SWVPDLPTLLGNGT LNKHSGIDFKQLNFLTKLNENHSGEVTPALLALP SLNPHKLLALYLF*VFPPVSGQGSGSNISSLLT PTCPAAMEGPLAGQ*HCREGAEGSRLEYKEEQG LQ*RVSPAQDFLASKCAPSARCLPVSTCSSSYSH HTLDAVWIPLQCTT*RHQFRRGPEPGCEVCFGH GKGHGLPTHTRAPHPTTCTQ*P*CND**GHDCP N*HG*CQVLFPMSWSHVCTCLGSPRSSAEEA*RH KQTLSRHVEFCSASVGTGDTGGTLC*PLQYGDW NEGESTTAYICVAGVVGDGENNCSGPWLLTYLF GYTVILSQGPVASLYMTDSNCEAAFFLVFAGGIG RPSAYHPTRYFPSCV*AHEDLHE*RPCKATQI* HDCAYP*EDAGQVGLEGPCLNSRGVGTWLGECT SPKQQASGCLPRLQSWYYPSHGVHPLPPSLPLWP QEGRAQSFVTCHMVSPNMGGISPACHNKVYYEN

Frame 2

PESR*VREDPRPLSPLTSPESQVRNGANPGEDP RSPLPEYTEPEPPHFPQLCSRIGSSCLLSDIRS ADTTSSSPPAHPDPPLPRV*RTQPGIIPQPRTP SQTPTSRGRSSGPLPPTQTLLSCRG*SLGFILLP WITPQSSGFPNPGDSAPGRCYGRHFHSVPGGQR SRRSPVAGQHGERPQPGGRSWLLPLALGLPRGP LCCG*DVDHAGGTDQCNEPWG*HPPASGSQSWTP *YCTEAIAVQGRHQCSE*TRECAPALCLFLGPR SSGRGPGGKWGPCQHL*QVWRDACGQSQGTPER ASPREDGPESQPYSIQGHILEGDHPHSAP*VTTV GRRVVKGNNPGLLGLG*GEAGYLTCPHS*EMEP *TNTLALTSNSLTS*RSSTRITLER*PLPFLPF PH*TPINYLLCTCFKFFLQLVGKEVAATFQAS*P LPVLQLWKGRWQGNDIVVKVLKVRDWSTRKSRD FNEECPRLRIFSHPNVLPVLGACQSPPAPHPTL ITHWMPYGSLYNVLHEGTNFVVDQSQAVKFALDM ARGMAFLHTLEPLIPRHALNSRSVMIDEDMTAR ISMADVKFSFQCPGRMYAPAWVAPEALQKKPED TNRRSADMWSFAVLLWELVTREVPFADLSNMEIG MKVRAQQHTFVLREWLVMVKITVVGLGSSHICS DIQ*SCPKGQWLLST*QTQIVRLLFFLYSQVAL EGLRPTIPPGISPHVCKLMKICMNEDPAKRPKFD MIVPILEKMQDK*DWKVLA*TPEVSGHGWGNAP PQSSRPLVASPASSHGTTPAMGSIPFPHPYHCG PKRGGLRALSLATWCLPTWEGSAPPVTIKFIMK

Sequence ILK.oAug05

AAGAGCGCCACGGGCGGGGCGGGGCCGGCGGCGGGCTGCGGGCGCGGCCGGACGGGAGTTCCCCGGAGAAGGATCCTGCAGCCCGAGTCCCGTCCTCAGG CTTCCCCAATCCAGGGGACTCGGCGCCGGGACGCTGCTATGGACGACATTTTCACTCAGTGCCGGGAGGGCAACGCAGTCGCCGTTCGCCTGTGGCTGGA CAACACGGAGAACGACCTCAACCAGGGTATCGTCTTGGATGCTTTGTGAAGAGCAGGTGGAAAGGAGGCAATTGCCTAGTTCATCGTAGAAGTAATGATG TCTTGGACTAGAATTAGGGGACGATCATGGCTTCTCCCCCTTGCACTGGGCCTGCCGAGAGGGCCGCTCTGCTGTGGTTGAGATGTTGATCATGCGGGGG GCACGGATCAATGTAATGAACCGTGGGGATGACACCCCCCTGCATCTGGCAGCCAGTCATGGACACCGTGATATTGTACAGAAGCTATTGCAGTACAAGG CAGACATCAATGCAGTGAATGAACACGGGAATGTGCCCCTGCACTATGCCTGTTTTTGGGGCCAAGATCAAGTGGCAGAGGACCTGGTGGCAAATGGGGC CCTTGTCAGCATCTGTAACAAGTATGGAGAGATGCCTGTGGACAAAGCCAAGGCACCCCTGAGAGAGCTTCTCCGAGAGCGGGCAGAGAAGATGGGCCAG AATCTCAACCGTATTCCATACAAGGACACATTCTGGAAGGGGACCACCCGCACTCGGCCCCGAAATGGAACCCTGAACAAACACTCTGGCATTGACTTCA AACAGCTTAACTTCCTGACGAAGCTCAACGAGAATCACTCTGGAGAGGTGACCCCTGCCCTTCTTGCCCTTCCCTCACTAAACCCCCATAAATTACTTGC TTTGTACCTGTTTTAAGTTTTTCCTCCAGTTAGTGGGCAAGGAAGTGGCAGCAACATTTCAAGCCTCCTAACCCCTACCTGTCCTGCAGCTATGGAAGGG CCGCTGGCAGGGCAATGACATTGTCGTGAAGGTGCTGAAGGTTCGAGACTGGAGTACAAGGAAGAGCAGGGACTTCAATGAAGAGTGTCCCCGGCTCAGG TAGTGCAAGGCGTAACCTGGAAGCTGCTAGTTCCAAGGAACCCTGAATAGCACTGAAAGAGATCTTTTGTACTGGGTCTCAACCACTCCCTCCCTCTTCT AGGATTTTCTCGCATCCAAATGTGCTCCCAGTGCTAGGTGCCTGCCAGTCTCCACCTGCTCCTCATCCTACTCTCATCACACACTGGATGCCGTATGGAT CCCTCTACAATGTACTACATGAAGGCACCAGTGAGTAGGGATGTTGAATTTCCTTGGGGAGGAAATGGCAGAGAGGGAGCCTCTCTGAACTATTTGACTT TTGCCTCCTCTCAGATTTCGTCGTGGACCAGAGCCAGGCTGTGAAGTTTGCTTTGGACATGGCAAGGGGCATGGCCTTCCTACACACACTAGAGCCCCTC ATCCCACGACATGCACTCAATAGCCGTAGTGTAATGGTGAGGCCACAAGCTCACTCCTGGCCCAGGCCCCAAAAGCCCTTTGCCTATCTATGACTTACCT CCTTCTATCTGTTTTCTCTTCCTCAGATTGATGAGGACATGACTGCCCGAATTAGCATGGCTGATGTCAAGTTCTCTTTCCAATGTCCTGGTCGCATGTA TGCACCTGCCTGGGTAGCCCCCGAAGGTGAGTGAAGTCATCATGTCGGGAGGTAAAAAAGGACCACCTCAGAAGTAGTGGAAGGGGGCAGAGACAGGACA GGCAAGGGGGCCAGAACAGACAAGCCCTATCTCTCCAGCTCTGCAGAAGAAGCCTGAAGACACAAACAGACGCTCAGCAGACATGTGGAGTTTTGCAGTG CTTCTGTGGGAACTGGTGACACGGGAGGTACCCTTTGCTGACCTCTCCAATATGGAGATTGGAATGAAGGTGAGAGCACAACAGCATACATTTGTGTTGC GGGAGTGGTTGGTGATGGTGAAAATAACTGTAGTGGGCCTTGGCTCCTCACATATTTGTTCGGATATACAGTAATCCTGTCCCAAGGGCCAGTGGCTTCT CTCTACATGACAGACTCAAATTGTGAGGCTGCTTTTTTTCTTGTATTCGCAGGTGGCATTGGAAGGCCTTCGGCCTACCATCCCACCAGGTATTTCCCCT CATGTGTGTAAGCTCATGAAGATCTGCATGAATGAAGACCCTGCAAAGCGACCCAAATTTGACATGATTGTGCCTATCCTTGAGAAGATGCAGGACAAGT AGGACTGGAAGGTCCTTGCCTGAACTCCAGAGGTGTCGGGACATGGTTGGGGGAATGCACCTCCCCAAAGCAGCAGGCCTCTGGTTGCCTCCCCCGCCTC CAGTCATGGTACTACCCCAGCCATGGGGTCCATCCCCTTCCCCCATCCCTACCACTGTGGCCCCAAGAGGGGCGGGCTCAGAGCTTTGTCACTTGCCACA TGGTGTCTCCCAACATGGGAGGGATCAGCCCCGCCTGTCACAATAAAGTTTATTATGAAAAC

ILK.F11 (forward primer)
ILK.R12 (reverse primer)
Alternative acceptor

Frame 0

KSATGGAGPAAGCGRGRTGVPRRRILQPESRPQ ASPIQGTRRRDAAMDDIFTQCREGNAVAVRLWLD NTENDLNQGIVLDAL*RAGGKEAIA*FIVEVMM SWTRIRGRSWLLPLALGLPRGPLCCG*DVDHAG GTDQCNEPWG*HPPASGSQSWTP*YCTEAIAVQG RHQCSE*TRECAPALCLFLGPRSSGRGPGGKWG PCQHL*QVWRDACGQSQGTPERASPRAGREDGP ESQPYSIQGHILEGDHPHSAPKWNPEQTLWH*LQ TA*LPDEAQRESLWRGDPCPSCPSLTKPP*ITC FVPVLSFSSS*WARKWQQHFKPPNPYLSCSYGR AAGRAMTLS*RC*RFETGVQGRAGTSMKSVPGSG SARRNLEAASSKEP*IALKEIFCTGSQPLPPSS RIFSHPNVLPVLGACQSPPAPHPTLITHWMPYG SLYNVLHEGTSE*GC*ISLGRKWQRGSLSELFDF CLLSDFVVDQSQAVKFALDMARGMAFLHTLEPL IPRHALNSRSVMVRPQAHSWPRPQKPFAYL*LT SFYLFSLPQIDEDMTARISMADVKFSFQCPGRMY APAWVAPEGE*SHHVGR*KRTTSEVVEGGRDRT GKGARTDKPYLSSSAEEA*RHKQTLSRHVEFCS ASVGTGDTGGTLC*PLQYGDWNEGESTTAYICVA GVVGDGENNCSGPWLLTYLFGYTVILSQGPVAS LYMTDSNCEAAFFLVFAGGIGRPSAYHPTRYFP SCV*AHEDLHE*RPCKATQI*HDCAYP*EDAGQV GLEGPCLNSRGVGTWLGECTSPKQQASGCLPRL QSWYYPSHGVHPLPPSLPLWPQEGRAQSFVTCH MVSPNMGGISPACHNKVYYEN

Frame 1

RAPRAGRGRRRAAGAAGREFPGEGSCSPSPVLR LPQSRGLGAGTLLWTTFSLSAGRATQSPFACGW TTRRTTSTRVSSWMLCEEQVERRQLPSSS*K**C LGLELGDDHGFSPLHWACREGRSAVVEMLIMRG ARINVMNRGDDTPLHLAASHGHRDIVQKLLQYK ADINAVNEHGNVPLHYACFWGQDQVAEDLVANGA LVSICNKYGEMPVDKAKAPLRELLRERAEKMGQ NLNRIPYKDTFWKGTTRTRPRNGTLNKHSGIDF KQLNFLTKLNENHSGEVTPALLALPSLNPHKLLA LYLF*VFPPVSGQGSGSNISSLLTPTCPAAMEG PLAGQ*HCREGAEGSRLEYKEEQGLQ*RVSPAQ VVQGVTWKLLVPRNPE*H*KRSFVLGLNHSLPLL GFSRIQMCSQC*VPASLHLLLILLSSHTGCRMD PSTMYYMKAPVSRDVEFPWGGNGREGASLNYLT FASSQISSWTRARL*SLLWTWQGAWPSYTH*SPS SHDMHSIAVV*W*GHKLTPGPGPKSPLPIYDLP PSICFLFLRLMRT*LPELAWLMSSSLSNVLVAC MHLPG*PPKVSEVIMSGGKKGPPQK*WKGAETGQ ARGPEQTSPISPALQKKPEDTNRRSADMWSFAV LLWELVTREVPFADLSNMEIGMKVRAQQHTFVL REWLVMVKITVVGLGSSHICSDIQ*SCPKGQWLL ST*QTQIVRLLFFLYSQVALEGLRPTIPPGISP HVCKLMKICMNEDPAKRPKFDMIVPILEKMQDK *DWKVLA*TPEVSGHGWGNAPPQSSRPLVASPAS SHGTTPAMGSIPFPHPYHCGPKRGGLRALSLAT WCLPTWEGSAPPVTIKFIMK

Frame 2

ERHGRGGAGGGLRARPDGSSPEKDPAARVPSSG FPNPGDSAPGRCYGRHFHSVPGGQRSRRSPVAG QHGERPQPGYRLGCFVKSRWKGGNCLVHRRSND VLD*N*GTIMASPPCTGPAERAALLWLRC*SCGG HGSM**TVGMTPPCIWQPVMDTVILYRSYCSTR QTSMQ*MNTGMCPCTMPVFGAKIKWQRTWWQMG PLSASVTSMERCLWTKPRHP*ESFSESGQRRWAR ISTVFHTRTHSGRGPPALGPEMEP*TNTLALTS NSLTS*RSSTRITLER*PLPFLPFPH*TPINYL LCTCFKFFLQLVGKEVAATFQAS*PLPVLQLWKG RWQGNDIVVKVLKVRDWSTRKSRDFNEECPRLR *CKA*PGSC*FQGTLNSTERDLLYWVSTTPSLF *DFLASKCAPSARCLPVSTCSSSYSHHTLDAVWI PLQCTT*RHQ*VGMLNFLGEEMAEREPL*TI*L LPPLRFRRGPEPGCEVCFGHGKGHGLPTHTRAP HPTTCTQ*P*CNGEATSSLLAQAPKALCLSMTYL LLSVFSSSD**GHDCPN*HG*CQVLFPMSWSHV CTCLGSPRR*VKSSCREVKKDHLRSSGRGQRQD RQGGQNRQALSLQLCRRSLKTQTDAQQTCGVLQC FCGNW*HGRYPLLTSPIWRLE*R*EHNSIHLCC GSGW*W*K*L*WALAPHIFVRIYSNPVPRASGF SLHDRLKL*GCFFSCIRRWHWKAFGLPSHQVFPL MCVSS*RSA*MKTLQSDPNLT*LCLSLRRCRTS RTGRSLPELQRCRDMVGGMHLPKAAGLWLPPPP PVMVLPQPWGPSPSPIPTTVAPRGAGSELCHLPH GVSQHGRDQPRLSQ*SLL*K

Sequence ILK.nAug05

AAGAGCGCCACGGGCGGGGCGGGGCCGGCGGCGGGCTGCGGGCGCGGCCGGACGGGAGTTCCCCGGAGAAGGATCCTGCAGCCCGAGTCCCGAGGATAAA GCTTGGGGTTCATCCTCCTTCCCTGGATCACTCCACAGTCCTCAGGCTTCCCCAATCCAGGGGACTCGGCGCCGGGACGCTGCTATGGACGACATTTTCA CTCAGTGCCGGGAGGGCAACGCAGTCGCCGTTCGCCTGTGGCTGGACAACACGGAGAACGACCTCAACCAGGGCTATTGCAGTACAAGGCAGACATCAAT GCAGTGAATGAACACGGGAATGTGCCCCTGCACTATGCCTGTTTTTGGGGCCAAGATCAAGTGGCAGAGGACCTGGTGGCAAATGGGGCCCTTGTCAGCA TCTGTAACAAGTATGGAGAGATGCCTGTGGACAAAGCCAAGGCACCCCTGAGAGAGCTTCTCCGAGAGCGGGCAGAGAAGATGGGCCAGAATCTCAACCG TATTCCATACAAGGACACATTCTGGAAGGGGACCACCCGCACTCGGCCCCGAAATGGAACCCTGAACAAACACTCTGGCATTGACTTCAAACAGCTTAAC TTCCTGACGAAGCTCAACGAGAATCACTCTGGAGAGCTATGGAAGGGCCGCTGGCAGGGCAATGACATTGTCGTGAAGGTGCTGAAGGTTCGAGACTGGA GTACAAGGAAGAGCAGGGACTTCAATGAAGAGTGTCCCCGGCTCAGGTAGTGCAAGGCGTAACCTGGAAGCTGCTAGTTCCAAGGAACCCTGAATAGCAC TGAAAGAGATCTTTTGTACTGGGTCTCAACCACTCCCTCCCTCTTCTAGGATTTTCTCGCATCCAAATGTGCTCCCAGTGCTAGGTGCCTGCCAGTCTCC ACCTGCTCCTCATCCTACTCTCATCACACACTGGATGCCGTATGGATCCCTCTACAATGTACTACATGAAGGCACCAGTGAGTAGGGATGTTGAATTTCC TTGGGGAGGAAATGGCAGAGAGGGAGCCTCTCTGAACTATTTGACTTTTGCCTCCTCTCAGATTTCGTCGTGGACCAGAGCCAGGCTGTGAAGTTTGCTT TGGACATGGCAAGGGGCATGGCCTTCCTACACACACTAGAGCCCCTCATCCCACGACATGCACTCAATAGCCGTAGTGTAATGGTGAGGCCACAAGCTCA CTCCTGGCCCAGGCCCCAAAAGCCCTTTGCCTATCTATGACTTACCTCCTTCTATCTGTTTTCTCTTCCTCAGATTGATGAGGACATGACTGCCCGAATT AGCATGGCTGATGTCAAGTTCTCTTTCCAATGTCCTGGTCGCATGTATGCACCTGCCTGGGTAGCCCCCGAAGGTGAGTGAAGTCATCATGTCGGGAGGT AAAAAAGGACCACCTCAGAAGTAGTGGAAGGGGGCAGAGACAGGACAGGCAAGGGGGCCAGAACAGACAAGCCCTATCTCTCCAGCTCTGCAGAAGAAGC CTGAAGACACAAACAGACGCTCAGCAGACATGTGGAGTTTTGCAGTGCTTCTGTGGGAACTGGTGACACGGGAGGTACCCTTTGCTGACCTCTCCAATAT GGAGATTGGAATGAAGGTGAGAGCACAACAGCATACATTTGTGTTGCGGGAGTGGTTGGTGATGGTGAAAATAACTGTAGTGGGCCTTGGCTCCTCACAT ATTTGTTCGGATATACAGTAATCCTGTCCCAAGGGCCAGTGGCTTCTCTCTACATGACAGACTCAAATTGTGAGGCTGCTTTTTTTCTTGTATTCGCAGG TGGCATTGGAAGGCCTTCGGCCTACCATCCCACCAGGTATTTCCCCTCATGTGTGTAAGCTCATGAAGATCTGCATGAATGAAGACCCTGCAAAGCGACC CAAATTTGACATGATTGTGCCTATCCTTGAGAAGATGCAGGACAAGTAGGACTGGAAGGTCCTTGCCTGAACTCCAGAGGTGTCGGGACATGGTTGGGGG AATGCACCTCCCCAAAGCAGCAGGCCTCTGGTTGCCTCCCCCGCCTCCAGTCATGGTACTACCCCAGCCATGGGGTCCATCCCCTTCCCCCATCCCTACC ACTGTGGCCCCAAGAGGGGCGGGCTCAGAGCTTTGTCACTTGCCACATGGTGTCTCCCAACATGGGAGGGATCAGCCCCGCCTGTCACAATAAAGTTTAT TATGAAAAC

ILK.F11 (forward primer)
ILK.R12 (reverse primer)
Alternative acceptor

Frame 0

KSATGGAGPAAGCGRGRTGVPRRRILQPESRG* SLGFILLPWITPQSSGFPNPGDSAPGRCYGRHFH SVPGGQRSRRSPVAGQHGERPQPGLLQYKADIN AVNEHGNVPLHYACFWGQDQVAEDLVANGALVS ICNKYGEMPVDKAKAPLRELLRERAEKMGQNLNR IPYKDTFWKGTTRTRPRNGTLNKHSGIDFKQLN FLTKLNENHSGELWKGRWQGNDIVVKVLKVRDW STRKSRDFNEECPRLR*CKA*PGSC*FQGTLNST ERDLLYWVSTTPSLF*DFLASKCAPSARCLPVS TCSSSYSHHTLDAVWIPLQCTT*RHQ*VGMLNF LGEEMAEREPL*TI*LLPPLRFRRGPEPGCEVCF GHGKGHGLPTHTRAPHPTTCTQ*P*CNGEATSS LLAQAPKALCLSMTYLLLSVFSSSD**GHDCPN *HG*CQVLFPMSWSHVCTCLGSPRR*VKSSCREV KKDHLRSSGRGQRQDRQGGQNRQALSLQLCRRS LKTQTDAQQTCGVLQCFCGNW*HGRYPLLTSPI WRLE*R*EHNSIHLCCGSGW*W*K*L*WALAPHI FVRIYSNPVPRASGFSLHDRLKL*GCFFSCIRR WHWKAFGLPSHQVFPLMCVSS*RSA*MKTLQSD PNLT*LCLSLRRCRTSRTGRSLPELQRCRDMVGG MHLPKAAGLWLPPPPPVMVLPQPWGPSPSPIPT TVAPRGAGSELCHLPHGVSQHGRDQPRLSQ*SL L*K

Frame 1

RAPRAGRGRRRAAGAAGREFPGEGSCSPSPEDK AWGSSSFPGSLHSPQASPIQGTRRRDAAMDDIF TQCREGNAVAVRLWLDNTENDLNQGYCSTRQTSM Q*MNTGMCPCTMPVFGAKIKWQRTWWQMGPLSA SVTSMERCLWTKPRHP*ESFSESGQRRWARIST VFHTRTHSGRGPPALGPEMEP*TNTLALTSNSLT S*RSSTRITLESYGRAAGRAMTLS*RC*RFETG VQGRAGTSMKSVPGSGSARRNLEAASSKEP*IA LKEIFCTGSQPLPPSSRIFSHPNVLPVLGACQSP PAPHPTLITHWMPYGSLYNVLHEGTSE*GC*IS LGRKWQRGSLSELFDFCLLSDFVVDQSQAVKFA LDMARGMAFLHTLEPLIPRHALNSRSVMVRPQAH SWPRPQKPFAYL*LTSFYLFSLPQIDEDMTARI SMADVKFSFQCPGRMYAPAWVAPEGE*SHHVGR *KRTTSEVVEGGRDRTGKGARTDKPYLSSSAEEA *RHKQTLSRHVEFCSASVGTGDTGGTLC*PLQY GDWNEGESTTAYICVAGVVGDGENNCSGPWLLT YLFGYTVILSQGPVASLYMTDSNCEAAFFLVFAG GIGRPSAYHPTRYFPSCV*AHEDLHE*RPCKAT QI*HDCAYP*EDAGQVGLEGPCLNSRGVGTWLG ECTSPKQQASGCLPRLQSWYYPSHGVHPLPPSLP LWPQEGRAQSFVTCHMVSPNMGGISPACHNKVY YEN

Frame 2

ERHGRGGAGGGLRARPDGSSPEKDPAARVPRIK LGVHPPSLDHSTVLRLPQSRGLGAGTLLWTTFS LSAGRATQSPFACGWTTRRTTSTRAIAVQGRHQ CSE*TRECAPALCLFLGPRSSGRGPGGKWGPCQH L*QVWRDACGQSQGTPERASPRAGREDGPESQP YSIQGHILEGDHPHSAPKWNPEQTLWH*LQTA* LPDEAQRESLWRAMEGPLAGQ*HCREGAEGSRLE YKEEQGLQ*RVSPAQVVQGVTWKLLVPRNPE*H *KRSFVLGLNHSLPLLGFSRIQMCSQC*VPASL HLLLILLSSHTGCRMDPSTMYYMKAPVSRDVEFP WGGNGREGASLNYLTFASSQISSWTRARL*SLL WTWQGAWPSYTH*SPSSHDMHSIAVV*W*GHKL TPGPGPKSPLPIYDLPPSICFLFLRLMRT*LPEL AWLMSSSLSNVLVACMHLPG*PPKVSEVIMSGG KKGPPQK*WKGAETGQARGPEQTSPISPALQKK PEDTNRRSADMWSFAVLLWELVTREVPFADLSNM EIGMKVRAQQHTFVLREWLVMVKITVVGLGSSH ICSDIQ*SCPKGQWLLST*QTQIVRLLFFLYSQ VALEGLRPTIPPGISPHVCKLMKICMNEDPAKRP KFDMIVPILEKMQDK*DWKVLA*TPEVSGHGWG NAPPQSSRPLVASPASSHGTTPAMGSIPFPHPY HCGPKRGGLRALSLATWCLPTWEGSAPPVTIKFI MK

Sequence ILK.mAug05

AAGAGCGCCACGGGCGGGGCGGGGCCGGCGGCGGGCTGCGGGCGCGGCCGGACGGGAGTTCCCCGGAGAAGGATCCTGCAGCCCGAGTCCCGAGGATAAA GCTTGGGGTTCATCCTCCTTCCCTGGATCACTCCACAGTCCTCAGGCTTCCCCAATCCAGGGGACTCGGCGCCGGGACGCTGCTATGGACGACATTTTCA CTCAGTGCCGGGAGGGCAACGCAGTCGCCGTTCGCCTGTGGCTGGACAACACGGAGAACGACCTCAACCAGGGTATCGTCTTGGATGCTTTGTGAAGAGC AGGTGGAAAGGAGGCAATTGCCTAGTTCATCGTAGAAGTAATGATGTCTTGGACTAGAATTAGGGGACGATCATGGCTTCTCCCCCTTGCACTGGGCCTG CCGAGAGGGCCGCTCTGCTGTGGTTGAGATGTTGATCATGCGGGGGGCACGGATCAATGTAATGAACCGTGGGGATGACACCCCCCTGCATCTGGCAGCC AGTCATGGACACCGTGATATTGTACAGAAGCTATTGCAGTACAAGGCAGACATCAATGCAGTGAATGAACACGGGAATGTGCCCCTGCACTATGCCTGTT TTTGGGGCCAAGATCAAGTGGCAGAGGACCTGGTGGCAAATGGGGCCCTTGTCAGCATCTGTAACAAGTATGGAGAGATGCCTGTGGACAAAGCCAAGGC ACCCCTGAGAGAGCTTCTCCGAGAGCGGGCAGAGAAGATGGGCCAGAATCTCAACCGTATTCCATACAAGGACACATTCTGGAAGGGGACCACCCGCACT CGGCCCCGAAATGGAACCCTGAACAAACACTCTGGCATTGACTTCAAACAGCTTAACTTCCTGACGAAGCTCAACGAGAATCACTCTGGAGAGCTATGGA AGGGCCGCTGGCAGGGCAATGACATTGTCGTGAAGGTGCTGAAGGTTCGAGACTGGAGTACAAGGAAGAGCAGGGACTTCAATGAAGAGTGTCCCCGGCT CAGGTAGTGCAAGGCGTAACCTGGAAGCTGCTAGTTCCAAGGAACCCTGAATAGCACTGAAAGAGATCTTTTGTACTGGGTCTCAACCACTCCCTCCCTC TTCTAGGATTTTCTCGCATCCAAATGTGCTCCCAGTGCTAGGTGCCTGCCAGTCTCCACCTGCTCCTCATCCTACTCTCATCACACACTGGATGCCGTAT GGATCCCTCTACAATGTACTACATGAAGGCACCAGTGAGTAGGGATGTTGAATTTCCTTGGGGAGGAAATGGCAGAGAGGGAGCCTCTCTGAACTATTTG ACTTTTGCCTCCTCTCAGATTTCGTCGTGGACCAGAGCCAGGCTGTGAAGTTTGCTTTGGACATGGCAAGGGGCATGGCCTTCCTACACACACTAGAGCC CCTCATCCCACGACATGCACTCAATAGCCGTAGTGTAATGGTGAGGCCACAAGCTCACTCCTGGCCCAGGCCCCAAAAGCCCTTTGCCTATCTATGACTT ACCTCCTTCTATCTGTTTTCTCTTCCTCAGATTGATGAGGACATGACTGCCCGAATTAGCATGGCTGATGTCAAGTTCTCTTTCCAATGTCCTGGTCGCA TGTATGCACCTGCCTGGGTAGCCCCCGAAGGTGAGTGAAGTCATCATGTCGGGAGGTAAAAAAGGACCACCTCAGAAGTAGTGGAAGGGGGCAGAGACAG GACAGGCAAGGGGGCCAGAACAGACAAGCCCTATCTCTCCAGCTCTGCAGAAGAAGCCTGAAGACACAAACAGACGCTCAGCAGACATGTGGAGTTTTGC AGTGCTTCTGTGGGAACTGGTGACACGGGAGGTACCCTTTGCTGACCTCTCCAATATGGAGATTGGAATGAAGGTGAGAGCACAACAGCATACATTTGTG TTGCGGGAGTGGTTGGTGATGGTGAAAATAACTGTAGTGGGCCTTGGCTCCTCACATATTTGTTCGGATATACAGTAATCCTGTCCCAAGGGCCAGTGGC TTCTCTCTACATGACAGACTCAAATTGTGAGGCTGCTTTTTTTCTTGTATTCGCAGGTGGCATTGGAAGGCCTTCGGCCTACCATCCCACCAGGTATTTC CCCTCATGTGTGTAAGCTCATGAAGATCTGCATGAATGAAGACCCTGCAAAGCGACCCAAATTTGACATGATTGTGCCTATCCTTGAGAAGATGCAGGAC AAGTAGGACTGGAAGGTCCTTGCCTGAACTCCAGAGGTGTCGGGACATGGTTGGGGGAATGCACCTCCCCAAAGCAGCAGGCCTCTGGTTGCCTCCCCCG CCTCCAGTCATGGTACTACCCCAGCCATGGGGTCCATCCCCTTCCCCCATCCCTACCACTGTGGCCCCAAGAGGGGCGGGCTCAGAGCTTTGTCACTTGC CACATGGTGTCTCCCAACATGGGAGGGATCAGCCCCGCCTGTCACAATAAAGTTTATTATGAAAAC

ILK.F11 (forward primer)
ILK.R12 (reverse primer)
Alternative acceptor

Frame 0

KSATGGAGPAAGCGRGRTGVPRRRILQPESRG* SLGFILLPWITPQSSGFPNPGDSAPGRCYGRHFH SVPGGQRSRRSPVAGQHGERPQPGYRLGCFVKS RWKGGNCLVHRRSNDVLD*N*GTIMASPPCTGP AERAALLWLRC*SCGGHGSM**TVGMTPPCIWQP VMDTVILYRSYCSTRQTSMQ*MNTGMCPCTMPV FGAKIKWQRTWWQMGPLSASVTSMERCLWTKPR HP*ESFSESGQRRWARISTVFHTRTHSGRGPPAL GPEMEP*TNTLALTSNSLTS*RSSTRITLESYG RAAGRAMTLS*RC*RFETGVQGRAGTSMKSVPG SGSARRNLEAASSKEP*IALKEIFCTGSQPLPPS SRIFSHPNVLPVLGACQSPPAPHPTLITHWMPY GSLYNVLHEGTSE*GC*ISLGRKWQRGSLSELF DFCLLSDFVVDQSQAVKFALDMARGMAFLHTLEP LIPRHALNSRSVMVRPQAHSWPRPQKPFAYL*L TSFYLFSLPQIDEDMTARISMADVKFSFQCPGR MYAPAWVAPEGE*SHHVGR*KRTTSEVVEGGRDR TGKGARTDKPYLSSSAEEA*RHKQTLSRHVEFC SASVGTGDTGGTLC*PLQYGDWNEGESTTAYIC VAGVVGDGENNCSGPWLLTYLFGYTVILSQGPVA SLYMTDSNCEAAFFLVFAGGIGRPSAYHPTRYF PSCV*AHEDLHE*RPCKATQI*HDCAYP*EDAG QVGLEGPCLNSRGVGTWLGECTSPKQQASGCLPR LQSWYYPSHGVHPLPPSLPLWPQEGRAQSFVTC HMVSPNMGGISPACHNKVYYEN

Frame 1

RAPRAGRGRRRAAGAAGREFPGEGSCSPSPEDK AWGSSSFPGSLHSPQASPIQGTRRRDAAMDDIF TQCREGNAVAVRLWLDNTENDLNQGIVLDAL*RA GGKEAIA*FIVEVMMSWTRIRGRSWLLPLALGL PRGPLCCG*DVDHAGGTDQCNEPWG*HPPASGS QSWTP*YCTEAIAVQGRHQCSE*TRECAPALCLF LGPRSSGRGPGGKWGPCQHL*QVWRDACGQSQG TPERASPRAGREDGPESQPYSIQGHILEGDHPH SAPKWNPEQTLWH*LQTA*LPDEAQRESLWRAME GPLAGQ*HCREGAEGSRLEYKEEQGLQ*RVSPA QVVQGVTWKLLVPRNPE*H*KRSFVLGLNHSLP LLGFSRIQMCSQC*VPASLHLLLILLSSHTGCRM DPSTMYYMKAPVSRDVEFPWGGNGREGASLNYL TFASSQISSWTRARL*SLLWTWQGAWPSYTH*S PSSHDMHSIAVV*W*GHKLTPGPGPKSPLPIYDL PPSICFLFLRLMRT*LPELAWLMSSSLSNVLVA CMHLPG*PPKVSEVIMSGGKKGPPQK*WKGAET GQARGPEQTSPISPALQKKPEDTNRRSADMWSFA VLLWELVTREVPFADLSNMEIGMKVRAQQHTFV LREWLVMVKITVVGLGSSHICSDIQ*SCPKGQW LLST*QTQIVRLLFFLYSQVALEGLRPTIPPGIS PHVCKLMKICMNEDPAKRPKFDMIVPILEKMQD K*DWKVLA*TPEVSGHGWGNAPPQSSRPLVASP ASSHGTTPAMGSIPFPHPYHCGPKRGGLRALSLA TWCLPTWEGSAPPVTIKFIMK

Frame 2

ERHGRGGAGGGLRARPDGSSPEKDPAARVPRIK LGVHPPSLDHSTVLRLPQSRGLGAGTLLWTTFS LSAGRATQSPFACGWTTRRTTSTRVSSWMLCEE QVERRQLPSSS*K**CLGLELGDDHGFSPLHWAC REGRSAVVEMLIMRGARINVMNRGDDTPLHLAA SHGHRDIVQKLLQYKADINAVNEHGNVPLHYAC FWGQDQVAEDLVANGALVSICNKYGEMPVDKAKA PLRELLRERAEKMGQNLNRIPYKDTFWKGTTRT RPRNGTLNKHSGIDFKQLNFLTKLNENHSGELW KGRWQGNDIVVKVLKVRDWSTRKSRDFNEECPRL R*CKA*PGSC*FQGTLNSTERDLLYWVSTTPSL F*DFLASKCAPSARCLPVSTCSSSYSHHTLDAV WIPLQCTT*RHQ*VGMLNFLGEEMAEREPL*TI* LLPPLRFRRGPEPGCEVCFGHGKGHGLPTHTRA PHPTTCTQ*P*CNGEATSSLLAQAPKALCLSMT YLLLSVFSSSD**GHDCPN*HG*CQVLFPMSWSH VCTCLGSPRR*VKSSCREVKKDHLRSSGRGQRQ DRQGGQNRQALSLQLCRRSLKTQTDAQQTCGVL QCFCGNW*HGRYPLLTSPIWRLE*R*EHNSIHLC CGSGW*W*K*L*WALAPHIFVRIYSNPVPRASG FSLHDRLKL*GCFFSCIRRWHWKAFGLPSHQVF PLMCVSS*RSA*MKTLQSDPNLT*LCLSLRRCRT SRTGRSLPELQRCRDMVGGMHLPKAAGLWLPPP PPVMVLPQPWGPSPSPIPTTVAPRGAGSELCHL PHGVSQHGRDQPRLSQ*SLL*K

Sequence ILK.lAug05

AGCCCGAGTCCCGGTGAGTGCGAGAGGACCCGCGCCCCCTGTCACCCCTCACTTCTCCTGAGTCCCAAAGGATAAAGCTTGGGGTTCATCCTCCTTCCCT GGATCACTCCACAGTCCTCAGGCTTCCCCAATCCAGGGGACTCGGCGCCGGGACGCTGCTATGGACGACATTTTCACTCAGTGCCGGGAGGGCAACGCAG TCGCCGTTCGCCTGTGGCTGGACAACACGGAGAACGACCTCAACCAGGGGGACGATCATGGCTTCTCCCCCTTGCACTGGGCCTGCCGAGAGGGCCGCTC TGCTGTGGTTGAGATGTTGATCATGCGGGGGGCACGGATCAATGTAATGAACCGTGGGGATGACACCCCCCTGCATCTGGCAGCCAGTCATGGACACCGT GATATTGTACAGAAGCTATTGCAGTACAAGGCAGACATCAATGCAGTGAATGAACACGGGAATGTGCCCCTGCACTATGCCTGTTTTTGGGGCCAAGATC AAGTGGCAGAGGACCTGGTGGCAAATGGGGCCCTTGTCAGCATCTGTAACAAGTATGGAGAGATGCCTGTGGACAAAGCCAAGGCACCCCTGAGAGAGCT TCTCCGAGAGCGGGCAGAGAAGATGGGCCAGAATCTCAACCGTATTCCATACAAGGACACATTCTGGAAGGGGACCACCCGCACTCGGCCCCGTGAGTCA CCACTGTGGGAAGAAGGGTTGTAAAAGGAAATAATCCTGGCCTCTTGGGGCTGGGTTAGGGTGAAGCTGGGTACCTGACCTGCCCACACTCTTAGGAAAT GGAACCCTGAACAAACACTCTGGCATTGACTTCAAACAGCTTAACTTCCTGACGAAGCTCAACGAGAATCACTCTGGAGAGGTGACCCCTGCCCTTCTTG CCCTTCCCTCACTAAACCCCCATAAATTACTTGCTTTGTACCTGTTTTAAGTTTTTCCTCCAGTTAGTGGGCAAGGAAGTGGCAGCAACATTTCAAGCCT CCTAACCCCTACCTGTCCTGCAGCTATGGAAGGGCCGCTGGCAGGGCAATGACATTGTCGTGAAGGTGCTGAAGGTTCGAGACTGGAGTACAAGGAAGAG CAGGGACTTCAATGAAGAGTGTCCCCGGCTCAGGTAGTGCAAGGCGTAACCTGGAAGCTGCTAGTTCCAAGGAACCCTGAATAGCACTGAAAGAGATCTT TTGTACTGGGTCTCAACCACTCCCTCCCTCTTCTAGGATTTTCTCGCATCCAAATGTGCTCCCAGTGCTAGGTGCCTGCCAGTCTCCACCTGCTCCTCAT CCTACTCTCATCACACACTGGATGCCGTATGGATCCCTCTACAATGTACTACATGAAGGCACCAGTGAGTAGGGATGTTGAATTTCCTTGGGGAGGAAAT GGCAGAGAGGGAGCCTCTCTGAACTATTTGACTTTTGCCTCCTCTCAGATTTCGTCGTGGACCAGAGCCAGGCTGTGAAGTTTGCTTTGGACATGGCAAG GGGCATGGCCTTCCTACACACACTAGAGCCCCTCATCCCACGACATGCACTCAATAGCCGTAGTGTAATGGTGAGGCCACAAGCTCACTCCTGGCCCAGG CCCCAAAAGCCCTTTGCCTATCTATGACTTACCTCCTTCTATCTGTTTTCTCTTCCTCAGATTGATGAGGACATGACTGCCCGAATTAGCATGGCTGATG TCAAGTTCTCTTTCCAATGTCCTGGTCGCATGTATGCACCTGCCTGGGTAGCCCCCGAAGGTGAGTGAAGTCATCATGTCGGGAGGTAAAAAAGGACCAC CTCAGAAGTAGTGGAAGGGGGCAGAGACAGGACAGGCAAGGGGGCCAGAACAGACAAGCCCTATCTCTCCAGCTCTGCAGAAGAAGCCTGAAGACACAAA CAGACGCTCAGCAGACATGTGGAGTTTTGCAGTGCTTCTGTGGGAACTGGTGACACGGGAGGTACCCTTTGCTGACCTCTCCAATATGGAGATTGGAATG AAGGTGAGAGCACAACAGCATACATTTGTGTTGCGGGAGTGGTTGGTGATGGTGAAAATAACTGTAGTGGGCCTTGGCTCCTCACATATTTGTTCGGATA TACAGTAATCCTGTCCCAAGGGCCAGTGGCTTCTCTCTACATGACAGACTCAAATTGTGAGGCTGCTTTTTTTCTTGTATTCGCAGGTGGCATTGGAAGG CCTTCGGCCTACCATCCCACCAGGTATTTCCCCTCATGTGTGTAAGCTCATGAAGATCTGCATGAATGAAGACCCTGCAAAGCGACCCAAATTTGACATG ATTGTGCCTATCCTTGAGAAGATGCAGGACAAGTAGGACTGGAAGGTCCTTGCCTGAACTCCAGAGGTGTCGGGACATGGTTGGGGGAATGCACCTCCCC AAAGCAGCAGGCCTCTGGTTGCCTCCCCCGCCTCCAGTCATGGTACTACCCCAGCCATGGGGTCCATCCCCTTCCCCCATCCCTACCACTGTGGCCCCAA GAGGGGCGGGCTCAGAGCTTTGTCACTTGCCACATGGTGTCTCCCAACATGGGAGGGATCAGCCCCGCCTGTCACAATAAAGTTTATTATGAAAAC

ILK.F11 (forward primer)
ILK.R12 (reverse primer)
Alternative acceptor

Frame 0

SPSPGECERTRAPCHPSLLLSPKG*SLGFILLP WITPQSSGFPNPGDSAPGRCYGRHFHSVPGGQRS RRSPVAGQHGERPQPGGRSWLLPLALGLPRGPL CCG*DVDHAGGTDQCNEPWG*HPPASGSQSWTP *YCTEAIAVQGRHQCSE*TRECAPALCLFLGPRS SGRGPGGKWGPCQHL*QVWRDACGQSQGTPERA SPRAGREDGPESQPYSIQGHILEGDHPHSAP*V TTVGRRVVKGNNPGLLGLG*GEAGYLTCPHS*EM EP*TNTLALTSNSLTS*RSSTRITLER*PLPFL PFPH*TPINYLLCTCFKFFLQLVGKEVAATFQA S*PLPVLQLWKGRWQGNDIVVKVLKVRDWSTRKS RDFNEECPRLR*CKA*PGSC*FQGTLNSTERDL LYWVSTTPSLF*DFLASKCAPSARCLPVSTCSS SYSHHTLDAVWIPLQCTT*RHQ*VGMLNFLGEEM AEREPL*TI*LLPPLRFRRGPEPGCEVCFGHGK GHGLPTHTRAPHPTTCTQ*P*CNGEATSSLLAQ APKALCLSMTYLLLSVFSSSD**GHDCPN*HG*C QVLFPMSWSHVCTCLGSPRR*VKSSCREVKKDH LRSSGRGQRQDRQGGQNRQALSLQLCRRSLKTQ TDAQQTCGVLQCFCGNW*HGRYPLLTSPIWRLE* R*EHNSIHLCCGSGW*W*K*L*WALAPHIFVRI YSNPVPRASGFSLHDRLKL*GCFFSCIRRWHWK AFGLPSHQVFPLMCVSS*RSA*MKTLQSDPNLT* LCLSLRRCRTSRTGRSLPELQRCRDMVGGMHLP KAAGLWLPPPPPVMVLPQPWGPSPSPIPTTVAP RGAGSELCHLPHGVSQHGRDQPRLSQ*SLL*K

Frame 1

ARVPVSARGPAPPVTPHFS*VPKDKAWGSSSFP GSLHSPQASPIQGTRRRDAAMDDIFTQCREGNA VAVRLWLDNTENDLNQGDDHGFSPLHWACREGRS AVVEMLIMRGARINVMNRGDDTPLHLAASHGHR DIVQKLLQYKADINAVNEHGNVPLHYACFWGQD QVAEDLVANGALVSICNKYGEMPVDKAKAPLREL LRERAEKMGQNLNRIPYKDTFWKGTTRTRPRES PLWEEGL*KEIILASWGWVRVKLGT*PAHTLRK WNPEQTLWH*LQTA*LPDEAQRESLWRGDPCPSC PSLTKPP*ITCFVPVLSFSSS*WARKWQQHFKP PNPYLSCSYGRAAGRAMTLS*RC*RFETGVQGR AGTSMKSVPGSGSARRNLEAASSKEP*IALKEIF CTGSQPLPPSSRIFSHPNVLPVLGACQSPPAPH PTLITHWMPYGSLYNVLHEGTSE*GC*ISLGRK WQRGSLSELFDFCLLSDFVVDQSQAVKFALDMAR GMAFLHTLEPLIPRHALNSRSVMVRPQAHSWPR PQKPFAYL*LTSFYLFSLPQIDEDMTARISMAD VKFSFQCPGRMYAPAWVAPEGE*SHHVGR*KRTT SEVVEGGRDRTGKGARTDKPYLSSSAEEA*RHK QTLSRHVEFCSASVGTGDTGGTLC*PLQYGDWN EGESTTAYICVAGVVGDGENNCSGPWLLTYLFGY TVILSQGPVASLYMTDSNCEAAFFLVFAGGIGR PSAYHPTRYFPSCV*AHEDLHE*RPCKATQI*H DCAYP*EDAGQVGLEGPCLNSRGVGTWLGECTSP KQQASGCLPRLQSWYYPSHGVHPLPPSLPLWPQ EGRAQSFVTCHMVSPNMGGISPACHNKVYYEN

Frame 2

PESR*VREDPRPLSPLTSPESQRIKLGVHPPSL DHSTVLRLPQSRGLGAGTLLWTTFSLSAGRATQ SPFACGWTTRRTTSTRGTIMASPPCTGPAERAA LLWLRC*SCGGHGSM**TVGMTPPCIWQPVMDTV ILYRSYCSTRQTSMQ*MNTGMCPCTMPVFGAKI KWQRTWWQMGPLSASVTSMERCLWTKPRHP*ES FSESGQRRWARISTVFHTRTHSGRGPPALGPVSH HCGKKGCKRK*SWPLGAGLG*SWVPDLPTLLGN GTLNKHSGIDFKQLNFLTKLNENHSGEVTPALL ALPSLNPHKLLALYLF*VFPPVSGQGSGSNISSL LTPTCPAAMEGPLAGQ*HCREGAEGSRLEYKEE QGLQ*RVSPAQVVQGVTWKLLVPRNPE*H*KRS FVLGLNHSLPLLGFSRIQMCSQC*VPASLHLLLI LLSSHTGCRMDPSTMYYMKAPVSRDVEFPWGGN GREGASLNYLTFASSQISSWTRARL*SLLWTWQ GAWPSYTH*SPSSHDMHSIAVV*W*GHKLTPGPG PKSPLPIYDLPPSICFLFLRLMRT*LPELAWLM SSSLSNVLVACMHLPG*PPKVSEVIMSGGKKGP PQK*WKGAETGQARGPEQTSPISPALQKKPEDTN RRSADMWSFAVLLWELVTREVPFADLSNMEIGM KVRAQQHTFVLREWLVMVKITVVGLGSSHICSD IQ*SCPKGQWLLST*QTQIVRLLFFLYSQVALEG LRPTIPPGISPHVCKLMKICMNEDPAKRPKFDM IVPILEKMQDK*DWKVLA*TPEVSGHGWGNAPP QSSRPLVASPASSHGTTPAMGSIPFPHPYHCGPK RGGLRALSLATWCLPTWEGSAPPVTIKFIMK

Sequence ILK.kAug05

AGCCCGAGTCCCGGTGAGTGCGAGAGGACCCGCGCCCCCTGTCACCCCTCACTTCTCCTGAGTCCCAATCCTCAGGCTTCCCCAATCCAGGGGACTCGGC GCCGGGACGCTGCTATGGACGACATTTTCACTCAGTGCCGGGAGGGCAACGCAGTCGCCGTTCGCCTGTGGCTGGACAACACGGAGAACGACCTCAACCA GGGGGACGATCATGGCTTCTCCCCCTTGCACTGGGCCTGCCGAGAGGGCCGCTCTGCTGTGGTTGAGATGTTGATCATGCGGGGGGCACGGATCAATGTA ATGAACCGTGGGGATGACACCCCCCTGCATCTGGCAGCCAGTCATGGACACCGTGATATTGTACAGAAGCTATTGCAGTACAAGGCAGACATCAATGCAG TGAATGAACACGGGAATGTGCCCCTGCACTATGCCTGTTTTTGGGGCCAAGATCAAGTGGCAGAGGACCTGGTGGCAAATGGGGCCCTTGTCAGCATCTG TAACAAGTATGGAGAGATGCCTGTGGACAAAGCCAAGGCACCCCTGAGAGAGCTTCTCCGAGAGCGGGCAGAGAAGATGGGCCAGAATCTCAACCGTATT CCATACAAGGACACATTCTGGAAGGGGACCACCCGCACTCGGCCCCGTGAGTCACCACTGTGGGAAGAAGGGTTGTAAAAGGAAATAATCCTGGCCTCTT GGGGCTGGGTTAGGGTGAAGCTGGGTACCTGACCTGCCCACACTCTTAGGAAATGGAACCCTGAACAAACACTCTGGCATTGACTTCAAACAGCTTAACT TCCTGACGAAGCTCAACGAGAATCACTCTGGAGAGGTGACCCCTGCCCTTCTTGCCCTTCCCTCACTAAACCCCCATAAATTACTTGCTTTGTACCTGTT TTAAGTTTTTCCTCCAGTTAGTGGGCAAGGAAGTGGCAGCAACATTTCAAGCCTCCTAACCCCTACCTGTCCTGCAGCTATGGAAGGGCCGCTGGCAGGG CAATGACATTGTCGTGAAGGTGCTGAAGGTTCGAGACTGGAGTACAAGGAAGAGCAGGGACTTCAATGAAGAGTGTCCCCGGCTCAGGATTTTCTCGCAT CCAAATGTGCTCCCAGTGCTAGGTGCCTGCCAGTCTCCACCTGCTCCTCATCCTACTCTCATCACACACTGGATGCCGTATGGATCCCTCTACAATGTAC TACATGAAGGCACCAGTGAGTAGGGATGTTGAATTTCCTTGGGGAGGAAATGGCAGAGAGGGAGCCTCTCTGAACTATTTGACTTTTGCCTCCTCTCAGA TTTCGTCGTGGACCAGAGCCAGGCTGTGAAGTTTGCTTTGGACATGGCAAGGGGCATGGCCTTCCTACACACACTAGAGCCCCTCATCCCACGACATGCA CTCAATAGCCGTAGTGTAATGGTGAGGCCACAAGCTCACTCCTGGCCCAGGCCCCAAAAGCCCTTTGCCTATCTATGACTTACCTCCTTCTATCTGTTTT CTCTTCCTCAGATTGATGAGGACATGACTGCCCGAATTAGCATGGCTGATGTCAAGTTCTCTTTCCAATGTCCTGGTCGCATGTATGCACCTGCCTGGGT AGCCCCCGAAGGTGAGTGAAGTCATCATGTCGGGAGGTAAAAAAGGACCACCTCAGAAGTAGTGGAAGGGGGCAGAGACAGGACAGGCAAGGGGGCCAGA ACAGACAAGCCCTATCTCTCCAGCTCTGCAGAAGAAGCCTGAAGACACAAACAGACGCTCAGCAGACATGTGGAGTTTTGCAGTGCTTCTGTGGGAACTG GTGACACGGGAGGTACCCTTTGCTGACCTCTCCAATATGGAGATTGGAATGAAGGTGAGAGCACAACAGCATACATTTGTGTTGCGGGAGTGGTTGGTGA TGGTGAAAATAACTGTAGTGGGCCTTGGCTCCTCACATATTTGTTCGGATATACAGTAATCCTGTCCCAAGGGCCAGTGGCTTCTCTCTACATGACAGAC TCAAATTGTGAGGCTGCTTTTTTTCTTGTATTCGCAGGTGGCATTGGAAGGCCTTCGGCCTACCATCCCACCAGGTATTTCCCCTCATGTGTGTAAGCTC ATGAAGATCTGCATGAATGAAGACCCTGCAAAGCGACCCAAATTTGACATGATTGTGCCTATCCTTGAGAAGATGCAGGACAAGTAGGACTGGAAGGTCC TTGCCTGAACTCCAGAGGTGTCGGGACATGGTTGGGGGAATGCACCTCCCCAAAGCAGCAGGCCTCTGGTTGCCTCCCCCGCCTCCAGTCATGGTACTAC CCCAGCCATGGGGTCCATCCCCTTCCCCCATCCCTACCACTGTGGCCCCAAGAGGGGCGGGCTCAGAGCTTTGTCACTTGCCACATGGTGTCTCCCAACA TGGGAGGGATCAGCCCCGCCTGTCACAATAAAGTTTATTATGAAAAC

ILK.F11 (forward primer)
ILK.R12 (reverse primer)
Alternative acceptor

Frame 0

SPSPGECERTRAPCHPSLLLSPNPQASPIQGTR RRDAAMDDIFTQCREGNAVAVRLWLDNTENDLNQ GDDHGFSPLHWACREGRSAVVEMLIMRGARINV MNRGDDTPLHLAASHGHRDIVQKLLQYKADINA VNEHGNVPLHYACFWGQDQVAEDLVANGALVSIC NKYGEMPVDKAKAPLRELLRERAEKMGQNLNRI PYKDTFWKGTTRTRPRESPLWEEGL*KEIILAS WGWVRVKLGT*PAHTLRKWNPEQTLWH*LQTA*L PDEAQRESLWRGDPCPSCPSLTKPP*ITCFVPV LSFSSS*WARKWQQHFKPPNPYLSCSYGRAAGR AMTLS*RC*RFETGVQGRAGTSMKSVPGSGFSRI QMCSQC*VPASLHLLLILLSSHTGCRMDPSTMY YMKAPVSRDVEFPWGGNGREGASLNYLTFASSQ ISSWTRARL*SLLWTWQGAWPSYTH*SPSSHDMH SIAVV*W*GHKLTPGPGPKSPLPIYDLPPSICF LFLRLMRT*LPELAWLMSSSLSNVLVACMHLPG *PPKVSEVIMSGGKKGPPQK*WKGAETGQARGPE QTSPISPALQKKPEDTNRRSADMWSFAVLLWEL VTREVPFADLSNMEIGMKVRAQQHTFVLREWLV MVKITVVGLGSSHICSDIQ*SCPKGQWLLST*QT QIVRLLFFLYSQVALEGLRPTIPPGISPHVCKL MKICMNEDPAKRPKFDMIVPILEKMQDK*DWKV LA*TPEVSGHGWGNAPPQSSRPLVASPASSHGTT PAMGSIPFPHPYHCGPKRGGLRALSLATWCLPT WEGSAPPVTIKFIMK

Frame 1

ARVPVSARGPAPPVTPHFS*VPILRLPQSRGLG AGTLLWTTFSLSAGRATQSPFACGWTTRRTTST RGTIMASPPCTGPAERAALLWLRC*SCGGHGSM* *TVGMTPPCIWQPVMDTVILYRSYCSTRQTSMQ *MNTGMCPCTMPVFGAKIKWQRTWWQMGPLSAS VTSMERCLWTKPRHP*ESFSESGQRRWARISTVF HTRTHSGRGPPALGPVSHHCGKKGCKRK*SWPL GAGLG*SWVPDLPTLLGNGTLNKHSGIDFKQLN FLTKLNENHSGEVTPALLALPSLNPHKLLALYLF *VFPPVSGQGSGSNISSLLTPTCPAAMEGPLAG Q*HCREGAEGSRLEYKEEQGLQ*RVSPAQDFLA SKCAPSARCLPVSTCSSSYSHHTLDAVWIPLQCT T*RHQ*VGMLNFLGEEMAEREPL*TI*LLPPLR FRRGPEPGCEVCFGHGKGHGLPTHTRAPHPTTC TQ*P*CNGEATSSLLAQAPKALCLSMTYLLLSVF SSSD**GHDCPN*HG*CQVLFPMSWSHVCTCLG SPRR*VKSSCREVKKDHLRSSGRGQRQDRQGGQ NRQALSLQLCRRSLKTQTDAQQTCGVLQCFCGNW *HGRYPLLTSPIWRLE*R*EHNSIHLCCGSGW* W*K*L*WALAPHIFVRIYSNPVPRASGFSLHDR LKL*GCFFSCIRRWHWKAFGLPSHQVFPLMCVSS *RSA*MKTLQSDPNLT*LCLSLRRCRTSRTGRS LPELQRCRDMVGGMHLPKAAGLWLPPPPPVMVL PQPWGPSPSPIPTTVAPRGAGSELCHLPHGVSQH GRDQPRLSQ*SLL*K

Frame 2

PESR*VREDPRPLSPLTSPESQSSGFPNPGDSA PGRCYGRHFHSVPGGQRSRRSPVAGQHGERPQP GGRSWLLPLALGLPRGPLCCG*DVDHAGGTDQC NEPWG*HPPASGSQSWTP*YCTEAIAVQGRHQCS E*TRECAPALCLFLGPRSSGRGPGGKWGPCQHL *QVWRDACGQSQGTPERASPRAGREDGPESQPY SIQGHILEGDHPHSAP*VTTVGRRVVKGNNPGLL GLG*GEAGYLTCPHS*EMEP*TNTLALTSNSLT S*RSSTRITLER*PLPFLPFPH*TPINYLLCTC FKFFLQLVGKEVAATFQAS*PLPVLQLWKGRWQG NDIVVKVLKVRDWSTRKSRDFNEECPRLRIFSH PNVLPVLGACQSPPAPHPTLITHWMPYGSLYNV LHEGTSE*GC*ISLGRKWQRGSLSELFDFCLLSD FVVDQSQAVKFALDMARGMAFLHTLEPLIPRHA LNSRSVMVRPQAHSWPRPQKPFAYL*LTSFYLF SLPQIDEDMTARISMADVKFSFQCPGRMYAPAWV APEGE*SHHVGR*KRTTSEVVEGGRDRTGKGAR TDKPYLSSSAEEA*RHKQTLSRHVEFCSASVGT GDTGGTLC*PLQYGDWNEGESTTAYICVAGVVGD GENNCSGPWLLTYLFGYTVILSQGPVASLYMTD SNCEAAFFLVFAGGIGRPSAYHPTRYFPSCV*A HEDLHE*RPCKATQI*HDCAYP*EDAGQVGLEGP CLNSRGVGTWLGECTSPKQQASGCLPRLQSWYY PSHGVHPLPPSLPLWPQEGRAQSFVTCHMVSPN MGGISPACHNKVYYEN

Sequence ILK.iAug05

AAGAGCGCCACGGGCGGGGCGGGGCCGGCGGCGGGCTGCGGGCGCGGCCGGACGGGAGTTCCCCGGAGAAGGATCCTGCAGCCCGAGTCCCGGGGACTCG GCGCCGGGACGCTGCTATGGACGACATTTTCACTCAGTGCCGGGAGGGCAACGCAGTCGCCGTTCGCCTGTGGCTGGACAACACGGAGAACGACCTCAAC CAGGGGGACGATCATGGCTTCTCCCCCTTGCACTGGGCCTGCCGAGAGGGCCGCTCTGCTGTGGTTGAGATGTTGATCATGCGGGGGGCACGGATCAATG TAATGAACCGTGGGGATGACACCCCCCTGCATCTGGCAGCCAGTCATGGACACCGTGATATTGTACAGAAGCTATTGCAGTACAAGGCAGACATCAATGC AGTGAATGAACACGGGAATGTGCCCCTGCACTATGCCTGTTTTTGGGGCCAAGATCAAGTGGCAGAGGACCTGGTGGCAAATGGGGCCCTTGTCAGCATC TGTAACAAGTATGGAGAGATGCCTGTGGACAAAGCCAAGGCACCCCTGAGAGAGCTTCTCCGAGAGCGGGCAGAGAAGATGGGCCAGAATCTCAACCGTA TTCCATACAAGGACACATTCTGGAAGGGGACCACCCGCACTCGGCCCCGAAATGGAACCCTGAACAAACACTCTGGCATTGACTTCAAACAGCTTAACTT CCTGACGAAGCTCAACGAGAATCACTCTGGAGAGCTATGGAAGGGCCGCTGGCAGGGCAATGACATTGTCGTGAAGGTGCTGAAGGTTCGAGACTGGAGT ACAAGGAAGAGCAGGGACTTCAATGAAGAGTGATTTTCTCGCATCCAAATGTGCTCCCAGTGCTAGGTGCCTGCCAGTCTCCACCTGCTCCTCATCCTAC TCTCATCACACACTGGATGCCGTATGGATCCCTCTACAATGTACTACATGAAGGCACCAGTGAGTAGGGATGTTGAATTTCCTTGGGGAGGAAATGGCAG AGAGGGAGCCTCTCTGAACTATTTGACTTTTGCCTCCTCTCAGATTTCGTCGTGGACCAGAGCCAGGCTGTGAAGTTTGCTTTGGACATGGCAAGGGGCA TGGCCTTCCTACACACACTAGAGCCCCTCATCCCACGACATGCACTCAATAGCCGTAGTGTAATGGTGAGGCCACAAGCTCACTCCTGGCCCAGGCCCCA AAAGCCCTTTGCCTATCTATGACTTACCTCCTTCTATCTGTTTTCTCTTCCTCAGATTGATGAGGACATGACTGCCCGAATTAGCATGGCTGATGTCAAG TTCTCTTTCCAATGTCCTGGTCGCATGTATGCACCTGCCTGGGTAGCCCCCGAAGGTGAGTGAAGTCATCATGTCGGGAGGTAAAAAAGGACCACCTCAG AAGTAGTGGAAGGGGGCAGAGACAGGACAGGCAAGGGGGCCAGAACAGACAAGCCCTATCTCTCCAGCTCTGCAGAAGAAGCCTGAAGACACAAACAGAC GCTCAGCAGACATGTGGAGTTTTGCAGTGCTTCTGTGGGAACTGGTGACACGGGAGGTACCCTTTGCTGACCTCTCCAATATGGAGATTGGAATGAAGGT GAGAGCACAACAGCATACATTTGTGTTGCGGGAGTGGTTGGTGATGGTGAAAATAACTGTAGTGGGCCTTGGCTCCTCACATATTTGTTCGGATATACAG TAATCCTGTCCCAAGGGCCAGTGGCTTCTCTCTACATGACAGACTCAAATTGTGAGGCTGCTTTTTTTCTTGTATTCGCAGGTGGCATTGGAAGGCCTTC GGCCTACCATCCCACCAGGTATTTCCCCTCATGTGTGTAAGCTCATGAAGATCTGCATGAATGAAGACCCTGCAAAGCGACCCAAATTTGACATGATTGT GCCTATCCTTGAGAAGATGCAGGACAAGTAGGACTGGAAGGTCCTTGCCTGAACTCCAGAGGTGTCGGGACATGGTTGGGGGAATGCACCTCCCCAAAGC AGCAGGCCTCTGGTTGCCTCCCCCGCCTCCAGTCATGGTACTACCCCAGCCATGGGGTCCATCCCCTTCCCCCATCCCTACCACTGTGGCCCCAAGAGGG GCGGGCTCAGAGCTTTGTCACTTGCCACATGGTGTCTCCCAACATGGGAGGGATCAGCCCCGCCTGTCACAATAAAGTTTATTATGAAAAC

ILK.F11 (forward primer)
ILK.R12 (reverse primer)
Alternative acceptor

Frame 0

KSATGGAGPAAGCGRGRTGVPRRRILQPESRGL GAGTLLWTTFSLSAGRATQSPFACGWTTRRTTST RGTIMASPPCTGPAERAALLWLRC*SCGGHGSM **TVGMTPPCIWQPVMDTVILYRSYCSTRQTSM Q*MNTGMCPCTMPVFGAKIKWQRTWWQMGPLSAS VTSMERCLWTKPRHP*ESFSESGQRRWARISTV FHTRTHSGRGPPALGPEMEP*TNTLALTSNSLT S*RSSTRITLESYGRAAGRAMTLS*RC*RFETGV QGRAGTSMKSDFLASKCAPSARCLPVSTCSSSY SHHTLDAVWIPLQCTT*RHQ*VGMLNFLGEEMA EREPL*TI*LLPPLRFRRGPEPGCEVCFGHGKGH GLPTHTRAPHPTTCTQ*P*CNGEATSSLLAQAP KALCLSMTYLLLSVFSSSD**GHDCPN*HG*CQ VLFPMSWSHVCTCLGSPRR*VKSSCREVKKDHLR SSGRGQRQDRQGGQNRQALSLQLCRRSLKTQTD AQQTCGVLQCFCGNW*HGRYPLLTSPIWRLE*R *EHNSIHLCCGSGW*W*K*L*WALAPHIFVRIYS NPVPRASGFSLHDRLKL*GCFFSCIRRWHWKAF GLPSHQVFPLMCVSS*RSA*MKTLQSDPNLT*L CLSLRRCRTSRTGRSLPELQRCRDMVGGMHLPKA AGLWLPPPPPVMVLPQPWGPSPSPIPTTVAPRG AGSELCHLPHGVSQHGRDQPRLSQ*SLL*K

Frame 1

RAPRAGRGRRRAAGAAGREFPGEGSCSPSPGDS APGRCYGRHFHSVPGGQRSRRSPVAGQHGERPQ PGGRSWLLPLALGLPRGPLCCG*DVDHAGGTDQC NEPWG*HPPASGSQSWTP*YCTEAIAVQGRHQC SE*TRECAPALCLFLGPRSSGRGPGGKWGPCQH L*QVWRDACGQSQGTPERASPRAGREDGPESQPY SIQGHILEGDHPHSAPKWNPEQTLWH*LQTA*L PDEAQRESLWRAMEGPLAGQ*HCREGAEGSRLE YKEEQGLQ*RVIFSHPNVLPVLGACQSPPAPHPT LITHWMPYGSLYNVLHEGTSE*GC*ISLGRKWQ RGSLSELFDFCLLSDFVVDQSQAVKFALDMARG MAFLHTLEPLIPRHALNSRSVMVRPQAHSWPRPQ KPFAYL*LTSFYLFSLPQIDEDMTARISMADVK FSFQCPGRMYAPAWVAPEGE*SHHVGR*KRTTS EVVEGGRDRTGKGARTDKPYLSSSAEEA*RHKQT LSRHVEFCSASVGTGDTGGTLC*PLQYGDWNEG ESTTAYICVAGVVGDGENNCSGPWLLTYLFGYT VILSQGPVASLYMTDSNCEAAFFLVFAGGIGRPS AYHPTRYFPSCV*AHEDLHE*RPCKATQI*HDC AYP*EDAGQVGLEGPCLNSRGVGTWLGECTSPK QQASGCLPRLQSWYYPSHGVHPLPPSLPLWPQEG RAQSFVTCHMVSPNMGGISPACHNKVYYEN

Frame 2

ERHGRGGAGGGLRARPDGSSPEKDPAARVPGTR RRDAAMDDIFTQCREGNAVAVRLWLDNTENDLN QGDDHGFSPLHWACREGRSAVVEMLIMRGARIN VMNRGDDTPLHLAASHGHRDIVQKLLQYKADINA VNEHGNVPLHYACFWGQDQVAEDLVANGALVSI CNKYGEMPVDKAKAPLRELLRERAEKMGQNLNR IPYKDTFWKGTTRTRPRNGTLNKHSGIDFKQLNF LTKLNENHSGELWKGRWQGNDIVVKVLKVRDWS TRKSRDFNEE*FSRIQMCSQC*VPASLHLLLIL LSSHTGCRMDPSTMYYMKAPVSRDVEFPWGGNGR EGASLNYLTFASSQISSWTRARL*SLLWTWQGA WPSYTH*SPSSHDMHSIAVV*W*GHKLTPGPGP KSPLPIYDLPPSICFLFLRLMRT*LPELAWLMSS SLSNVLVACMHLPG*PPKVSEVIMSGGKKGPPQ K*WKGAETGQARGPEQTSPISPALQKKPEDTNR RSADMWSFAVLLWELVTREVPFADLSNMEIGMKV RAQQHTFVLREWLVMVKITVVGLGSSHICSDIQ *SCPKGQWLLST*QTQIVRLLFFLYSQVALEGL RPTIPPGISPHVCKLMKICMNEDPAKRPKFDMIV PILEKMQDK*DWKVLA*TPEVSGHGWGNAPPQS SRPLVASPASSHGTTPAMGSIPFPHPYHCGPKR GGLRALSLATWCLPTWEGSAPPVTIKFIMK

Sequence ILK.hAug05

AGCCCGAGTCCCGGTGAGTGCGAGAGGACCCGCGCCCCCTGTCACCCCTCACTTCTCCTGAGTCCCAATCCTCAGGCTTCCCCAATCCAGGGGACTCGGC GCCGGGACGCTGCTATGGACGACATTTTCACTCAGTGCCGGGAGGGCAACGCAGTCGCCGTTCGCCTGTGGCTGGACAACACGGAGAACGACCTCAACCA GGGCTATTGCAGTACAAGGCAGACATCAATGCAGTGAATGAACACGGGAATGTGCCCCTGCACTATGCCTGTTTTTGGGGCCAAGATCAAGTGGCAGAGG ACCTGGTGGCAAATGGGGCCCTTGTCAGCATCTGTAACAAGTATGGAGAGATGCCTGTGGACAAAGCCAAGGCACCCCTGAGAGAGCTTCTCCGAGAGCG GGCAGAGAAGATGGGCCAGAATCTCAACCGTATTCCATACAAGGACACATTCTGGAAGGGGACCACCCGCACTCGGCCCCGAAATGGAACCCTGAACAAA CACTCTGGCATTGACTTCAAACAGCTTAACTTCCTGACGAAGCTCAACGAGAATCACTCTGGAGAGCTATGGAAGGGCCGCTGGCAGGGCAATGACATTG TCGTGAAGGTGCTGAAGGTTCGAGACTGGAGTACAAGGAAGAGCAGGGACTTCAATGAAGAGTGTCCCCGGCTCAGGATTTTCTCGCATCCAAATGTGCT CCCAGTGCTAGGTGCCTGCCAGTCTCCACCTGCTCCTCATCCTACTCTCATCACACACTGGATGCCGTATGGATCCCTCTACAATGTACTACATGAAGGC ACCAGTGAGTAGGGATGTTGAATTTCCTTGGGGAGGAAATGGCAGAGAGGGAGCCTCTCTGAACTATTTGACTTTTGCCTCCTCTCAGATTTCGTCGTGG ACCAGAGCCAGGCTGTGAAGTTTGCTTTGGACATGGCAAGGGGCATGGCCTTCCTACACACACTAGAGCCCCTCATCCCACGACATGCACTCAATAGCCG TAGTGTAATGGTGAGGCCACAAGCTCACTCCTGGCCCAGGCCCCAAAAGCCCTTTGCCTATCTATGACTTACCTCCTTCTATCTGTTTTCTCTTCCTCAG ATTGATGAGGACATGACTGCCCGAATTAGCATGGCTGATGTCAAGTTCTCTTTCCAATGTCCTGGTCGCATGTATGCACCTGCCTGGGTAGCCCCCGAAG GTGAGTGAAGTCATCATGTCGGGAGGTAAAAAAGGACCACCTCAGAAGTAGTGGAAGGGGGCAGAGACAGGACAGGCAAGGGGGCCAGAACAGACAAGCC CTATCTCTCCAGCTCTGCAGAAGAAGCCTGAAGACACAAACAGACGCTCAGCAGACATGTGGAGTTTTGCAGTGCTTCTGTGGGAACTGGTGACACGGGA GGTACCCTTTGCTGACCTCTCCAATATGGAGATTGGAATGAAGGTGAGAGCACAACAGCATACATTTGTGTTGCGGGAGTGGTTGGTGATGGTGAAAATA ACTGTAGTGGGCCTTGGCTCCTCACATATTTGTTCGGATATACAGTAATCCTGTCCCAAGGGCCAGTGGCTTCTCTCTACATGACAGACTCAAATTGTGA GGCTGCTTTTTTTCTTGTATTCGCAGGTGGCATTGGAAGGCCTTCGGCCTACCATCCCACCAGGTATTTCCCCTCATGTGTGTAAGCTCATGAAGATCTG CATGAATGAAGACCCTGCAAAGCGACCCAAATTTGACATGATTGTGCCTATCCTTGAGAAGATGCAGGACAAGTAGGACTGGAAGGTCCTTGCCTGAACT CCAGAGGTGTCGGGACATGGTTGGGGGAATGCACCTCCCCAAAGCAGCAGGCCTCTGGTTGCCTCCCCCGCCTCCAGTCATGGTACTACCCCAGCCATGG GGTCCATCCCCTTCCCCCATCCCTACCACTGTGGCCCCAAGAGGGGCGGGCTCAGAGCTTTGTCACTTGCCACATGGTGTCTCCCAACATGGGAGGGATC AGCCCCGCCTGTCACAATAAAGTTTATTATGAAAAC

ILK.F11 (forward primer)
ILK.R12 (reverse primer)
Alternative acceptor

Frame 0

SPSPGECERTRAPCHPSLLLSPNPQASPIQGTR RRDAAMDDIFTQCREGNAVAVRLWLDNTENDLNQ GYCSTRQTSMQ*MNTGMCPCTMPVFGAKIKWQR TWWQMGPLSASVTSMERCLWTKPRHP*ESFSES GQRRWARISTVFHTRTHSGRGPPALGPEMEP*TN TLALTSNSLTS*RSSTRITLESYGRAAGRAMTL S*RC*RFETGVQGRAGTSMKSVPGSGFSRIQMC SQC*VPASLHLLLILLSSHTGCRMDPSTMYYMKA PVSRDVEFPWGGNGREGASLNYLTFASSQISSW TRARL*SLLWTWQGAWPSYTH*SPSSHDMHSIA VV*W*GHKLTPGPGPKSPLPIYDLPPSICFLFLR LMRT*LPELAWLMSSSLSNVLVACMHLPG*PPK VSEVIMSGGKKGPPQK*WKGAETGQARGPEQTS PISPALQKKPEDTNRRSADMWSFAVLLWELVTRE VPFADLSNMEIGMKVRAQQHTFVLREWLVMVKI TVVGLGSSHICSDIQ*SCPKGQWLLST*QTQIV RLLFFLYSQVALEGLRPTIPPGISPHVCKLMKIC MNEDPAKRPKFDMIVPILEKMQDK*DWKVLA*T PEVSGHGWGNAPPQSSRPLVASPASSHGTTPAM GSIPFPHPYHCGPKRGGLRALSLATWCLPTWEGS APPVTIKFIMK

Frame 1

ARVPVSARGPAPPVTPHFS*VPILRLPQSRGLG AGTLLWTTFSLSAGRATQSPFACGWTTRRTTST RAIAVQGRHQCSE*TRECAPALCLFLGPRSSGRG PGGKWGPCQHL*QVWRDACGQSQGTPERASPRA GREDGPESQPYSIQGHILEGDHPHSAPKWNPEQ TLWH*LQTA*LPDEAQRESLWRAMEGPLAGQ*HC REGAEGSRLEYKEEQGLQ*RVSPAQDFLASKCA PSARCLPVSTCSSSYSHHTLDAVWIPLQCTT*R HQ*VGMLNFLGEEMAEREPL*TI*LLPPLRFRRG PEPGCEVCFGHGKGHGLPTHTRAPHPTTCTQ*P *CNGEATSSLLAQAPKALCLSMTYLLLSVFSSS D**GHDCPN*HG*CQVLFPMSWSHVCTCLGSPRR *VKSSCREVKKDHLRSSGRGQRQDRQGGQNRQA LSLQLCRRSLKTQTDAQQTCGVLQCFCGNW*HG RYPLLTSPIWRLE*R*EHNSIHLCCGSGW*W*K* L*WALAPHIFVRIYSNPVPRASGFSLHDRLKL* GCFFSCIRRWHWKAFGLPSHQVFPLMCVSS*RS A*MKTLQSDPNLT*LCLSLRRCRTSRTGRSLPEL QRCRDMVGGMHLPKAAGLWLPPPPPVMVLPQPW GPSPSPIPTTVAPRGAGSELCHLPHGVSQHGRD QPRLSQ*SLL*K

Frame 2

PESR*VREDPRPLSPLTSPESQSSGFPNPGDSA PGRCYGRHFHSVPGGQRSRRSPVAGQHGERPQP GLLQYKADINAVNEHGNVPLHYACFWGQDQVAE DLVANGALVSICNKYGEMPVDKAKAPLRELLRER AEKMGQNLNRIPYKDTFWKGTTRTRPRNGTLNK HSGIDFKQLNFLTKLNENHSGELWKGRWQGNDI VVKVLKVRDWSTRKSRDFNEECPRLRIFSHPNVL PVLGACQSPPAPHPTLITHWMPYGSLYNVLHEG TSE*GC*ISLGRKWQRGSLSELFDFCLLSDFVV DQSQAVKFALDMARGMAFLHTLEPLIPRHALNSR SVMVRPQAHSWPRPQKPFAYL*LTSFYLFSLPQ IDEDMTARISMADVKFSFQCPGRMYAPAWVAPE GE*SHHVGR*KRTTSEVVEGGRDRTGKGARTDKP YLSSSAEEA*RHKQTLSRHVEFCSASVGTGDTG GTLC*PLQYGDWNEGESTTAYICVAGVVGDGEN NCSGPWLLTYLFGYTVILSQGPVASLYMTDSNCE AAFFLVFAGGIGRPSAYHPTRYFPSCV*AHEDL HE*RPCKATQI*HDCAYP*EDAGQVGLEGPCLN SRGVGTWLGECTSPKQQASGCLPRLQSWYYPSHG VHPLPPSLPLWPQEGRAQSFVTCHMVSPNMGGI SPACHNKVYYEN

Sequence ILK.fAug05

AGCCCGAGTCCCGGTGAGTGCGAGAGGACCCGCGCCCCCTGTCACCCCTCACTTCTCCTGAGTCCCAAGTAAGGAACGGAGCCAACCCTGGGGAGGACCC CCGGTCCCCTCTCCCAGAGTATACGGAGCCTGAACCTCCCCACTTCCCCCAACTCTGTTCGCGGATAGGGTCTAGTTGCCTGCTCTCGGACATCCGTTCA GCAGACACTACCTCTTCGTCACCCCCTGCCCACCCTGACCCGCCTTTACCTCGCGTCTAGAGGACACAGCCAGGGATCATCCCGCAGCCCCGAACTCCTT CACAGACCCCCACTAGCCGGGGACGCAGCTCAGGCCCCCTACCCCCAACACAAACACTTCTCTCCTGTAGAGGATAAAGCTTGGGGTTCATCCTCCTTCC CTGGATCACTCCACAGTCCTCAGGCTTCCCCAATCCAGGGGACTCGGCGCCGGGACGCTGCTATGGACGACATTTTCACTCAGTGCCGGGAGGGCAACGC AGTCGCCGTTCGCCTGTGGCTGGACAACACGGAGAACGACCTCAACCAGGGGTGAGCTGAAACGGTTGGTGGATGAGAGGAAGGCTAGAGATCTCCTGGC TACGTGGAGTGGAGTGCTCATGTCTGGTGGTGGCGGCTGCCTTTGCTAGCCAGTGTAATGAGTGCTAAGCATAGCCTGTGGGGGGCAGAGGGTTTTCACA GAGGACGCAGTTTGAGCTGAATCTTGACTGCAGAATAAGAGTTTCACAGGCAGAGGCTACAGAGAGCTTTCCAGCCTCAGTAGACTGCATGGCCAAAGGC TAGGGGGCAAGGCACAGAGCAGAGAGAACAGGAAATTGTCTGGAGTTCCATATGGCTGGAGGATAGATGATCTCTGTGGGTCGGAGCATTGGGTACAAGA GGAAAAGAACAGGACATAAGACTGTAGAGGTCTCCAAGGATCAGCCAGATCATGCAAGCATATTTAGGCTATAAGAAGGTCTTTATTTTAAAAGCAAGGT TTTAAAGCTGTATAGTGACATAATGAGATTGTCCATTTTTCAGTATCGTCTTGGATGCTTTGTGAAGAGCAGGTGGAAAGGAGGCAATTGCCTAGTTCAT CGTAGAAGTAATGATGTCTTGGACTAGAATTAGGGTGAGTGAAAAAGAGAAGTGATCAAATTCCAGAAGTCTTTAGGACGAAGAATTGTGGAACTTGGTG TGGGGAGTGAGTAAGGGCAAAGATGAGGACCAGGGTTCTGGCTTGGGAACTTGGTTGTTTTTACTGAGATGGAGAAAACTGGAGGATGAGGCATTTTATT TTGGACATGTTAAAGTTAAGGTGACAATACAGCAAGGTGGAAATGTTGAGTGTGTTGTTGGTTATGCAGATTTGCAATTCAGGGGAGGAATCTGACTTGG AGACACAGATTTGAGAGCTATCAGCATATAGATAGCATATATATATCATATATATAGATGATACTTGAAGACGTGGTTGTGAAGGAGAACGTCTCAGGAG AGTGGAAGGCAAGAGGTCAGGGGACAGGAAGCCTGCACGACAGAAAAGGAGCAACCGCAAGTTGAAAAAGAAATAGGAAAATGTGTGAGTAAAGCTTACA GAAGAGAATGTTTTAATGAAGGGGAGGTAGTCAACGGCAGTACAGGCTACTGAGAGATCAAAGAACATTAATATTTTAAAGTAGCCATTGAATTTACAGT TGGGTTTTTTTTTTTTAAGTTAAGGGGTACATGTGCAGGTTTGTTGGATGGGTAAACTCAGGTCATGGAGGTTTGTTGTGCAGATCATTTCATCACCCAG GTATTAAGCCGTGGCACCCATTAGTTATTTTTCCTGATCCCTCCCTCTTCCTACCCGCCCCACTCTGGTAGGCCCCAGTGTCTGTTGCTCCCCTCAGTGT GCAGTTAGGATGTATTTGACCATCTGTGAGTGTTGTTTCAGAATAATGGGTGAAGAAATCAGACTACATTGGGTTCCTTAATTTAAGGCACTATGATGAA CACCTTCTGTGCTGGGTGCTAGAGTCCAGAATCTGACATAATCTCTGCTCTCGATACAGCAGATTTGTGGCAGATTGAAAAGTAGGCCGGGCGCGGTGGC TCACGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGCTGGTGGATCACGAGGTCAGGAGTTCGAGACCAGCCTGACCAACATGGTGAAACCCTGTCTCTA CTAAAAATACAAAAATTAGCCAGGCGTGGTGGCGTGCGCCTGTAATCCCAGCTACTCGGAGGCTGAGGCAGGAGAACTGCTTGAACCCGGGAAGCAGAGG CTGCAGTGAGCCAAGATCATGCCACTGCCCTCCAGCCTGGGCCACAGAGCAAGACTCTGTCTTAAAAAAGAAAAAGAAAACAAAAGTTGAGAGGTGAGCA AATAGTGAAAGTGAATGTACACCAGTTCTACAAGGTTGGCTGAGATAGGAAGGCAAGAAGAGCAGTAGTGATGGTGACTCAGAGTGGCAAAATCAAATTC TTTATTTTTTAAAATTGGTGGAGTTTAGTTTTTAGGTTTGACAGGTCAGGATCACCTGTCATCTTAGTCTAGACTTCACTGGTTCCCATTAGGTTCTACA CTATTTCTCTTTAATACTTTGCAAAGTCATTTGTTCCATTTTTCATATAATTCTCAAAGGGTACCCTGATAAAGACAGTAAGCACTGTTACTGTTTTGTT GGTGAGGAAATAGAGGCTTAGGCAGTTGCCCAGTGGGCCTAGCATCTAGGAAGACTCTAGCTGAGTCTAGGAAGACTCTAGGAAGATGCTGCCAGAAGGA AAAGGGGTGGAATTAATGAAACTGGAAGGTTGTGGTGCTGGTTTGAGGAGTAAAGTATGGGGGCCAAAGTTGGCTATATGCTGGATATGAAGAGGGGGTT AATTCCTTGCAGGTCTTCTTGAGATAGAAGTCCAGGCCCTGAGGTGGCAGGCAGCCTGATAGTGAACAGAACCCTTGTGCCCATACTTTTGCCCCCCGAG TTTGGCCTGCCCTGGCGCCACAGGCAGTACTGGAAGCTGATAAGTCAGGGCACAAATTAAAGGTCTAGGAGGCAAGACCAACTGATAAACAGGGGGCGTA ATGCTTCCTGGGGATAATCCCATCTCAAGGAAAAGCTTTTGGCTATTTCTGTGTTAGCAGATGCGAGCAAGTTGTGGAGGAAAATGATTAACTTAAAGGC CACACCCCCCAACCCCTTCAGCTGTACGGGCATCTGGATGGCCAGACCCCTGATCAGCTCCAGGCCTTGCCTAGAGTCGCACACAGGAAGTGACCACAAC ACTAAGGCATCCGGAGGCTGCTGGCCCAGACCACGGACCGCCCCCTGCTCCGCCCCTTGAATCTGCAGCCCCGAACTGGAGGGAATTTCCTTTTATGGCC CCAGGCTGTCAGGCAGGCCCAGCTCCAAACCAATTGTTTTGTTTTGTTTGTATACTTTACTTTATAAAATACATATTTCTTGGAAAAGAAAAAAATCAGG TATAGTTTTAATCCCAAAACAGCCATTCTCATTTTCTTCTGTTTTCTATGCACAGGATTGCTAAGTAGGGGAATCCTGCTTTGCATGGTGGTTTGTTATC TACCTCATCAGTAGTCAAAAGCATTTCTCCTTTTCAACATAAACCCTTCCAAAACATCATTTAAATTCCATTCCATTTTTAGATGTTAGTTTCAGTACCA GAGCCAAATAGTAAGTTTGTTCCCTCTTCTATAAGTTGTGGCCTGCCTTCTCCAAGACACCCTTCTCCCCCACTAACATGCACTGAACAGCTGCTGTCAA TCCATTCCCTCAAGAAACTTAAAGGTCTAACAGACAAGACAGTCCATTAACAGATTTTTACAATCCAGTGCAACAAGTGCTGAAGTAGGGGGACATATAA GATGTGGTGGAAAACAGAAAGGACCAATAGATGTTGCAGAAGGGGTGCAAGAGAAACCAGGGGAAGAGCACTACCACCTAAGGAAATGAGATGTGGGATA TGGTGAAGATAACACATTTTTTTATAGAGGTTGTTGAGATATCTAGGTGGTTGGTTTGGTTTGAAGCTCAGGGGAAGGTCTGAAATGGACAGCTTTGGGA GTTGCTGGCATGAATGAGAATCAAAGTCCTAGAGAGGTAAGCCTTCCCAGAGAGTATGTAATTATCAGTTTTTCAGGAATCAAAACCTTTGCCCCATCCC ACCTCCAGCTCAATGACCATTGCCCCTTCCTCAAAGGGACGATCATGGCTTCTCCCCCTTGCACTGGGCCTGCCGAGAGGGCCGCTCTGCTGTGGTTGAG ATGTTGATCATGCGGGGGGCACGGATCAATGTAATGAACCGTGGGGATGACACCCCCCTGCATCTGGCAGCCAGTCATGGACACCGTGATATTGTACAGA AGGTACGTACAAACTCCTTCGTCATCCACATCACATACATGCCATGAGGGTCAGTCACAGGCACTGTAACATACAGTAGAAAGCATGTGTGCTCTTCCCC CTTTTCCCATGCCCTGACACCAGTATCTCATTTGGAACTGACTGTACTTTCTGCCTCTTCTTTTTGTCTGGCCATGGGGTCCAGCTATTGCAGTACAAGG CAGACATCAATGCAGTGAATGAACACGGGAATGTGCCCCTGCACTATGCCTGTTTTTGGGGCCAAGATCAAGTGGCAGAGGACCTGGTGGCAAATGGGGC CCTTGTCAGCATCTGTAACAAGTATGGAGAGATGCCTGTGGACAAAGCCAAGGCACCCCTGAGAGAGCTTCTCCGAGAGCGGGCAGAGAAGATGGGCCAG AATCTCAACCGTATTCCATACAAGGACACATTCTGGAAGGGGACCACCCGCACTCGGCCCCGAAATGGAACCCTGAACAAACACTCTGGCATTGACTTCA AACAGCTTAACTTCCTGACGAAGCTCAACGAGAATCACTCTGGAGAGCTATGGAAGGGCCGCTGGCAGGGCAATGACATTGTCGTGAAGGTGCTGAAGGT TCGAGACTGGAGTACAAGGAAGAGCAGGGACTTCAATGAAGAGTGTCCCCGGCTCAGGATTTTCTCGCATCCAAATGTGCTCCCAGTGCTAGGTGCCTGC CAGTCTCCACCTGCTCCTCATCCTACTCTCATCACACACTGGATGCCGTATGGATCCCTCTACAATGTACTACATGAAGGCACCAATTTCGTCGTGGACC AGAGCCAGGCTGTGAAGTTTGCTTTGGACATGGCAAGGGGCATGGCCTTCCTACACACACTAGAGCCCCTCATCCCACGACATGCACTCAATAGCCGTAG TGTAATGATTGATGAGGACATGACTGCCCGAATTAGCATGGCTGATGTCAAGTTCTCTTTCCAATGTCCTGGTCGCATGTATGCACCTGCCTGGGTAGCC CCCGAAGGTGAGTGAAGTCATCATGTCGGGAGGTAAAAAAGGACCACCTCAGAAGTAGTGGAAGGGGGCAGAGACAGGACAGGCAAGGGGGCCAGAACAG ACAAGCCCTATCTCTCCAGCTCTGCAGAAGAAGCCTGAAGACACAAACAGACGCTCAGCAGACATGTGGAGTTTTGCAGTGCTTCTGTGGGAACTGGTGA CACGGGAGGTACCCTTTGCTGACCTCTCCAATATGGAGATTGGAATGAAGGTGAGAGCACAACAGCATACATTTGTGTTGCGGGAGTGGTTGGTGATGGT GAAAATAACTGTAGTGGGCCTTGGCTCCTCACATATTTGTTCGGATATACAGTAATCCTGTCCCAAGGGCCAGTGGCTTCTCTCTACATGACAGACTCAA ATTGTGAGGCTGCTTTTTTTCTTGTATTCGCAGGTGGCATTGGAAGGCCTTCGGCCTACCATCCCACCAGGTATTTCCCCTCATGTGTGTAAGCTCATGA AGATCTGCATGAATGAAGACCCTGCAAAGCGACCCAAATTTGACATGATTGTGCCTATCCTTGAGAAGATGCAGGACAAGTAGGACTGGAAGGTCCTTGC CTGAACTCCAGAGGTGTCGGGACATGGTTGGGGGAATGCACCTCCCCAAAGCAGCAGGCCTCTGGTTGCCTCCCCCGCCTCCAGTCATGGTACTACCCCA GCCATGGGGTCCATCCCCTTCCCCCATCCCTACCACTGTGGCCCCAAGAGGGGCGGGCTCAGAGCTTTGTCACTTGCCACATGGTGTCTCCCAACATGGG AGGGATCAGCCCCGCCTGTCACAATAAAGTTTATTATGAAAAC

ILK.F11 (forward primer)
ILK.R12 (reverse primer)
Alternative acceptor

Frame 0

SPSPGECERTRAPCHPSLLLSPK*GTEPTLGRT PGPLSQSIRSLNLPTSPNSVRG*GLVACSRTSVQ QTLPLRHPLPTLTRLYLASRGHSQGSSRSPELL HRPPLAGDAAQAPYPQHKHFSPVEDKAWGSSSF PGSLHSPQASPIQGTRRRDAAMDDIFTQCREGNA VAVRLWLDNTENDLNQG*AETVGG*EEG*RSPG YVEWSAHVWWWRLPLLASVMSAKHSLWGAEGFH RGRSLS*ILTAE*EFHRQRLQRAFQPQ*TAWPKA RGQGTEQREQEIVWSSIWLEDR*SLWVGALGTR GKEQDIRL*RSPRISQIMQAYLGYKKVFILKAR F*SCIVT**DCPFFSIVLDAL*RAGGKEAIA*FI VEVMMSWTRIRVSEKEK*SNSRSL*DEELWNLV WGVSKGKDEDQGSGLGTWLFLLRWRKLEDEAFY FGHVKVKVTIQQGGNVECVVGYADLQFRGGI*LG DTDLRAISI*IAYIYHIYR*YLKTWL*RRTSQE SGRQEVRGQEACTTEKEQPQVEKEIGKCVSKAY RRECFNEGEVVNGSTGY*EIKEH*YFKVAIEFTV GFFFFKLRGTCAGLLDG*TQVMEVCCADHFITQ VLSRGTH*LFFLIPPSSYPPHSGRPQCLLLPSV CS*DVFDHL*VLFQNNG*RNQTTLGSLI*GTMMN TFCAGC*SPESDIISALDTADLWQIEK*AGRGG SRL*SQHFGRPRLVDHEVRSSRPA*PTW*NPVS TKNTKISQAWWRAPVIPATRRLRQENCLNPGSRG CSEPRSCHCPPAWATEQDSVLKKKKKTKVER*A NSESECTPVLQGWLR*EGKKSSSDGDSEWQNQI LYFLKLVEFSF*V*QVRITCHLSLDFTGSH*VLH YFSLILCKVICSIFHIILKGYPDKDSKHCYCFV GEEIEA*AVAQWA*HLGRL*LSLGRL*EDAARR KRGGINETGRLWCWFEE*SMGAKVGYMLDMKRGL IPCRSS*DRSPGPEVAGSLIVNRTLVPILLPPE FGLPWRHRQYWKLISQGTN*RSRRQDQLINRGR NASWG*SHLKEKLLAISVLADASKLWRKMINLKA TPPNPFSCTGIWMARPLISSRPCLESHTGSDHN TKASGGCWPRPRTAPCSAP*ICSPELEGISFYG PRLSGRPSSKPIVLFCLYTLLYKIHISWKRKKSG IVLIPKQPFSFSSVFYAQDC*VGESCFAWWFVI YLISSQKHFSFST*TLPKHHLNSIPFLDVSFST RAK**VCSLFYKLWPAFSKTPFSPTNMH*TAAVN PFPQET*RSNRQDSPLTDFYNPVQQVLK*GDI* DVVENRKDQ*MLQKGCKRNQGKSTTT*GNEMWD MVKITHFFIEVVEISRWLVWFEAQGKV*NGQLWE LLA*MRIKVLER*AFPESM*LSVFQESKPLPHP TSSSMTIAPSSKGRSWLLPLALGLPRGPLCCG* DVDHAGGTDQCNEPWG*HPPASGSQSWTP*YCTE GTYKLLRHPHHIHAMRVSHRHCNIQ*KACVLFP LFPCPDTSISFGTDCTFCLFFLSGHGVQLLQYK ADINAVNEHGNVPLHYACFWGQDQVAEDLVANGA LVSICNKYGEMPVDKAKAPLRELLRERAEKMGQ NLNRIPYKDTFWKGTTRTRPRNGTLNKHSGIDF KQLNFLTKLNENHSGELWKGRWQGNDIVVKVLKV RDWSTRKSRDFNEECPRLRIFSHPNVLPVLGAC QSPPAPHPTLITHWMPYGSLYNVLHEGTNFVVD QSQAVKFALDMARGMAFLHTLEPLIPRHALNSRS VMIDEDMTARISMADVKFSFQCPGRMYAPAWVA PEGE*SHHVGR*KRTTSEVVEGGRDRTGKGART DKPYLSSSAEEA*RHKQTLSRHVEFCSASVGTGD TGGTLC*PLQYGDWNEGESTTAYICVAGVVGDG ENNCSGPWLLTYLFGYTVILSQGPVASLYMTDS NCEAAFFLVFAGGIGRPSAYHPTRYFPSCV*AHE DLHE*RPCKATQI*HDCAYP*EDAGQVGLEGPC LNSRGVGTWLGECTSPKQQASGCLPRLQSWYYP SHGVHPLPPSLPLWPQEGRAQSFVTCHMVSPNMG GISPACHNKVYYEN

Frame 1

ARVPVSARGPAPPVTPHFS*VPSKERSQPWGGP PVPSPRVYGA*TSPLPPTLFADRV*LPALGHPF SRHYLFVTPCPP*PAFTSRLEDTARDHPAAPNSF TDPH*PGTQLRPPTPNTNTSLL*RIKLGVHPPS LDHSTVLRLPQSRGLGAGTLLWTTFSLSAGRAT QSPFACGWTTRRTTSTRGELKRLVDERKARDLLA TWSGVLMSGGGGCLC*PV**VLSIACGGQRVFT EDAV*AES*LQNKSFTGRGYRELSSLSRLHGQR LGGKAQSRENRKLSGVPYGWRIDDLCGSEHWVQE EKNRT*DCRGLQGSARSCKHI*AIRRSLF*KQG FKAV**HNEIVHFSVSSWMLCEEQVERRQLPSS S*K**CLGLELG*VKKRSDQIPEVFRTKNCGTWC GE*VRAKMRTRVLAWELGCFY*DGENWRMRHFI LDMLKLR*QYSKVEMLSVLLVMQICNSGEESDL ETQI*ELSAYR*HIYIIYIDDT*RRGCEGERLRR VEGKRSGDRKPARQKRSNRKLKKK*ENV*VKLT EENVLMKGR*STAVQATERSKNINILK*PLNLQ LGFFFLS*GVHVQVCWMGKLRSWRFVVQIISSPR Y*AVAPISYFS*SLPLPTRPTLVGPSVCCSPQC AVRMYLTICECCFRIMGEEIRLHWVP*FKAL** TPSVLGARVQNLT*SLLSIQQICGRLKSRPGAVA HACNPSTLGGRGWWITRSGVRDQPDQHGETLSL LKIQKLARRGGVRL*SQLLGG*GRRTA*TREAE AAVSQDHATALQPGPQSKTLS*KRKRKQKLRGEQ IVKVNVHQFYKVG*DRKARRAVVMVTQSGKIKF FIF*NWWSLVFRFDRSGSPVILV*TSLVPIRFY TISL*YFAKSFVPFFI*FSKGTLIKTVSTVTVLL VRK*RLRQLPSGPSI*EDSS*V*EDSRKMLPEG KGVELMKLEGCGAGLRSKVWGPKLAICWI*RGG *FLAGLLEIEVQALRWQAA***TEPLCPYFCPPS LACPGATGSTGS**VRAQIKGLGGKTN**TGGV MLPGDNPISRKSFWLFLC*QMRASCGGK*LT*R PHPPTPSAVRASGWPDP*SAPGLA*SRTQEVTTT LRHPEAAGPDHGPPPAPPLESAAPNWREFPFMA PGCQAGPAPNQLFCFVCILYFIKYIFLGKEKNQ V*F*SQNSHSHFLLFSMHRIAK*GNPALHGGLLS TSSVVKSISPFQHKPFQNII*IPFHF*MLVSVP EPNSKFVPSSISCGLPSPRHPSPPLTCTEQLLS IHSLKKLKGLTDKTVH*QIFTIQCNKC*SRGTYK MWWKTERTNRCCRRGARETRGRALPPKEMRCGI W*R*HIFL*RLLRYLGGWFGLKLRGRSEMDSFG SCWHE*ESKS*RGKPSQRVCNYQFFRNQNLCPIP PPAQ*PLPLPQRDDHGFSPLHWACREGRSAVVE MLIMRGARINVMNRGDDTPLHLAASHGHRDIVQ KVRTNSFVIHITYMP*GSVTGTVTYSRKHVCSSP FSHALTPVSHLELTVLSASSFCLAMGSSYCSTR QTSMQ*MNTGMCPCTMPVFGAKIKWQRTWWQMG PLSASVTSMERCLWTKPRHP*ESFSESGQRRWAR ISTVFHTRTHSGRGPPALGPEMEP*TNTLALTS NSLTS*RSSTRITLESYGRAAGRAMTLS*RC*R FETGVQGRAGTSMKSVPGSGFSRIQMCSQC*VPA SLHLLLILLSSHTGCRMDPSTMYYMKAPISSWT RARL*SLLWTWQGAWPSYTH*SPSSHDMHSIAV V**LMRT*LPELAWLMSSSLSNVLVACMHLPG*P PKVSEVIMSGGKKGPPQK*WKGAETGQARGPEQ TSPISPALQKKPEDTNRRSADMWSFAVLLWELV TREVPFADLSNMEIGMKVRAQQHTFVLREWLVMV KITVVGLGSSHICSDIQ*SCPKGQWLLST*QTQ IVRLLFFLYSQVALEGLRPTIPPGISPHVCKLM KICMNEDPAKRPKFDMIVPILEKMQDK*DWKVLA *TPEVSGHGWGNAPPQSSRPLVASPASSHGTTP AMGSIPFPHPYHCGPKRGGLRALSLATWCLPTW EGSAPPVTIKFIMK

Frame 2

PESR*VREDPRPLSPLTSPESQVRNGANPGEDP RSPLPEYTEPEPPHFPQLCSRIGSSCLLSDIRS ADTTSSSPPAHPDPPLPRV*RTQPGIIPQPRTP SQTPTSRGRSSGPLPPTQTLLSCRG*SLGFILLP WITPQSSGFPNPGDSAPGRCYGRHFHSVPGGQR SRRSPVAGQHGERPQPGVS*NGWWMRGRLEISW LRGVECSCLVVAAAFASQCNEC*A*PVGGRGFSQ RTQFELNLDCRIRVSQAEATESFPASVDCMAKG *GARHRAERTGNCLEFHMAGG*MISVGRSIGYK RKRTGHKTVEVSKDQPDHASIFRL*EGLYFKSKV LKLYSDIMRLSIFQYRLGCFVKSRWKGGNCLVH RRSNDVLD*N*GE*KREVIKFQKSLGRRIVELG VGSE*GQR*GPGFWLGNLVVFTEMEKTGG*GILF WTC*S*GDNTARWKC*VCCWLCRFAIQGRNLTW RHRFESYQHIDSIYISYI*MILEDVVVKENVSG EWKARGQGTGSLHDRKGATAS*KRNRKMCE*SLQ KRMF**RGGSQRQYRLLRDQRTLIF*SSH*IYS WVFFF*VKGYMCRFVGWVNSGHGGLLCRSFHHP GIKPWHPLVIFPDPSLFLPAPLW*APVSVAPLSV QLGCI*PSVSVVSE*WVKKSDYIGFLNLRHYDE HLLCWVLESRI*HNLCSRYSRFVAD*KVGRARW LTPVIPALWEAEAGGSRGQEFETSLTNMVKPCLY *KYKN*PGVVACACNPSYSEAEAGELLEPGKQR LQ*AKIMPLPSSLGHRARLCLKKEKENKS*EVS K**K*MYTSSTRLAEIGRQEEQ**W*LRVAKSNS LFFKIGGV*FLGLTGQDHLSS*SRLHWFPLGST LFLFNTLQSHLFHFSYNSQRVP**RQ*ALLLFC W*GNRGLGSCPVGLASRKTLAESRKTLGRCCQKE KGWN**NWKVVVLV*GVKYGGQSWLYAGYEEGV NSLQVFLR*KSRP*GGRQPDSEQNPCAHTFAPR VWPALAPQAVLEADKSGHKLKV*EARPTDKQGA* CFLGIIPSQGKAFGYFCVSRCEQVVEEND*LKG HTPQPLQLYGHLDGQTPDQLQALPRVAHRK*PQ H*GIRRLLAQTTDRPLLRPLNLQPRTGGNFLLWP QAVRQAQLQTNCFVLFVYFTL*NTYFLEKKKIR YSFNPKTAILIFFCFLCTGLLSRGILLCMVVCY LPHQ*SKAFLLFNINPSKTSFKFHSIFRC*FQYQ SQIVSLFPLL*VVACLLQDTLLPH*HALNSCCQ SIPSRNLKV*QTRQSINRFLQSSATSAEVGGHI RCGGKQKGPIDVAEGVQEKPGEEHYHLRK*DVGY GEDNTFFYRGC*DI*VVGLV*SSGEGLKWTALG VAGMNENQSPREVSLPREYVIISFSGIKTFAPS HLQLNDHCPFLKGTIMASPPCTGPAERAALLWLR C*SCGGHGSM**TVGMTPPCIWQPVMDTVILYR RYVQTPSSSTSHTCHEGQSQAL*HTVESMCALP PFPMP*HQYLIWN*LYFLPLLFVWPWGPAIAVQG RHQCSE*TRECAPALCLFLGPRSSGRGPGGKWG PCQHL*QVWRDACGQSQGTPERASPRAGREDGP ESQPYSIQGHILEGDHPHSAPKWNPEQTLWH*LQ TA*LPDEAQRESLWRAMEGPLAGQ*HCREGAEG SRLEYKEEQGLQ*RVSPAQDFLASKCAPSARCL PVSTCSSSYSHHTLDAVWIPLQCTT*RHQFRRGP EPGCEVCFGHGKGHGLPTHTRAPHPTTCTQ*P* CND**GHDCPN*HG*CQVLFPMSWSHVCTCLGS PRR*VKSSCREVKKDHLRSSGRGQRQDRQGGQNR QALSLQLCRRSLKTQTDAQQTCGVLQCFCGNW* HGRYPLLTSPIWRLE*R*EHNSIHLCCGSGW*W *K*L*WALAPHIFVRIYSNPVPRASGFSLHDRLK L*GCFFSCIRRWHWKAFGLPSHQVFPLMCVSS* RSA*MKTLQSDPNLT*LCLSLRRCRTSRTGRSL PELQRCRDMVGGMHLPKAAGLWLPPPPPVMVLPQ PWGPSPSPIPTTVAPRGAGSELCHLPHGVSQHG RDQPRLSQ*SLL*K

Sequence ILK.dAug05

AAGAGCGCCACGGGCGGGGCGGGGCCGGCGGCGGGCTGCGGGCGCGGCCGGACGGGAGTTCCCCGGAGAAGGATCCTGCAGCCCGAGTCCCGTCCTCAGG CTTCCCCAATCCAGGGGACTCGGCGCCGGGACGCTGCTATGGACGACATTTTCACTCAGTGCCGGGAGGGCAACGCAGTCGCCGTTCGCCTGTGGCTGGA CAACACGGAGAACGACCTCAACCAGGGCTATTGCAGTACAAGGCAGACATCAATGCAGTGAATGAACACGGGAATGTGCCCCTGCACTATGCCTGTTTTT GGGGCCAAGATCAAGTGGCAGAGGACCTGGTGGCAAATGGGGCCCTTGTCAGCATCTGTAACAAGTATGGAGAGATGCCTGTGGACAAAGCCAAGGCACC CCTGAGAGAGCTTCTCCGAGAGCGGGCAGAGAAGATGGGCCAGAATCTCAACCGTATTCCATACAAGGACACATTCTGGAAGGGGACCACCCGCACTCGG CCCCGAAATGGAACCCTGAACAAACACTCTGGCATTGACTTCAAACAGCTTAACTTCCTGACGAAGCTCAACGAGAATCACTCTGGAGAGCTATGGAAGG GCCGCTGGCAGGGCAATGACATTGTCGTGAAGGTGCTGAAGGTTCGAGACTGGAGTACAAGGAAGAGCAGGGACTTCAATGAAGAGTGTCCCCGGCTCAG GATTTTCTCGCATCCAAATGTGCTCCCAGTGCTAGGTGCCTGCCAGTCTCCACCTGCTCCTCATCCTACTCTCATCACACACTGGATGCCGTATGGATCC CTCTACAATGTACTACATGAAGGCACCAATTTCGTCGTGGACCAGAGCCAGGCTGTGAAGTTTGCTTTGGACATGGCAAGGGGCATGGCCTTCCTACACA CACTAGAGCCCCTCATCCCACGACATGCACTCAATAGCCGTAGTGTAATGATTGATGAGGACATGACTGCCCGAATTAGCATGGCTGATGTCAAGTTCTC TTTCCAATGTCCTGGTCGCATGTATGCACCTGCCTGGGTAGCCCCCGAAGGTGAGTGAAGTCATCATGTCGGGAGGTAAAAAAGGACCACCTCAGAAGTA GTGGAAGGGGGCAGAGACAGGACAGGCAAGGGGGCCAGAACAGACAAGCCCTATCTCTCCAGCTCTGCAGAAGAAGCCTGAAGACACAAACAGACGCTCA GCAGACATGTGGAGTTTTGCAGTGCTTCTGTGGGAACTGGTGACACGGGAGGTACCCTTTGCTGACCTCTCCAATATGGAGATTGGAATGAAGGTGAGAG CACAACAGCATACATTTGTGTTGCGGGAGTGGTTGGTGATGGTGAAAATAACTGTAGTGGGCCTTGGCTCCTCACATATTTGTTCGGATATACAGTAATC CTGTCCCAAGGGCCAGTGGCTTCTCTCTACATGACAGACTCAAATTGTGAGGCTGCTTTTTTTCTTGTATTCGCAGGTGGCATTGGAAGGCCTTCGGCCT ACCATCCCACCAGGTATTTCCCCTCATGTGTGTAAGCTCATGAAGATCTGCATGAATGAAGACCCTGCAAAGCGACCCAAATTTGACATGATTGTGCCTA TCCTTGAGAAGATGCAGGACAAGTAGGACTGGAAGGTCCTTGCCTGAACTCCAGAGGTGTCGGGACATGGTTGGGGGAATGCACCTCCCCAAAGCAGCAG GCCTCTGGTTGCCTCCCCCGCCTCCAGTCATGGTACTACCCCAGCCATGGGGTCCATCCCCTTCCCCCATCCCTACCACTGTGGCCCCAAGAGGGGCGGG CTCAGAGCTTTGTCACTTGCCACATGGTGTCTCCCAACATGGGAGGGATCAGCCCCGCCTGTCACAATAAAGTTTATTATGAAAAC

ILK.F11 (forward primer)
ILK.R12 (reverse primer)
Alternative acceptor

Frame 0

KSATGGAGPAAGCGRGRTGVPRRRILQPESRPQ ASPIQGTRRRDAAMDDIFTQCREGNAVAVRLWLD NTENDLNQGYCSTRQTSMQ*MNTGMCPCTMPVF GAKIKWQRTWWQMGPLSASVTSMERCLWTKPRH P*ESFSESGQRRWARISTVFHTRTHSGRGPPALG PEMEP*TNTLALTSNSLTS*RSSTRITLESYGR AAGRAMTLS*RC*RFETGVQGRAGTSMKSVPGS GFSRIQMCSQC*VPASLHLLLILLSSHTGCRMDP STMYYMKAPISSWTRARL*SLLWTWQGAWPSYT H*SPSSHDMHSIAVV**LMRT*LPELAWLMSSS LSNVLVACMHLPG*PPKVSEVIMSGGKKGPPQK* WKGAETGQARGPEQTSPISPALQKKPEDTNRRS ADMWSFAVLLWELVTREVPFADLSNMEIGMKVR AQQHTFVLREWLVMVKITVVGLGSSHICSDIQ*S CPKGQWLLST*QTQIVRLLFFLYSQVALEGLRP TIPPGISPHVCKLMKICMNEDPAKRPKFDMIVP ILEKMQDK*DWKVLA*TPEVSGHGWGNAPPQSSR PLVASPASSHGTTPAMGSIPFPHPYHCGPKRGG LRALSLATWCLPTWEGSAPPVTIKFIMK

Frame 1

RAPRAGRGRRRAAGAAGREFPGEGSCSPSPVLR LPQSRGLGAGTLLWTTFSLSAGRATQSPFACGW TTRRTTSTRAIAVQGRHQCSE*TRECAPALCLFL GPRSSGRGPGGKWGPCQHL*QVWRDACGQSQGT PERASPRAGREDGPESQPYSIQGHILEGDHPHS APKWNPEQTLWH*LQTA*LPDEAQRESLWRAMEG PLAGQ*HCREGAEGSRLEYKEEQGLQ*RVSPAQ DFLASKCAPSARCLPVSTCSSSYSHHTLDAVWI PLQCTT*RHQFRRGPEPGCEVCFGHGKGHGLPTH TRAPHPTTCTQ*P*CND**GHDCPN*HG*CQVL FPMSWSHVCTCLGSPRR*VKSSCREVKKDHLRS SGRGQRQDRQGGQNRQALSLQLCRRSLKTQTDAQ QTCGVLQCFCGNW*HGRYPLLTSPIWRLE*R*E HNSIHLCCGSGW*W*K*L*WALAPHIFVRIYSN PVPRASGFSLHDRLKL*GCFFSCIRRWHWKAFGL PSHQVFPLMCVSS*RSA*MKTLQSDPNLT*LCL SLRRCRTSRTGRSLPELQRCRDMVGGMHLPKAA GLWLPPPPPVMVLPQPWGPSPSPIPTTVAPRGAG SELCHLPHGVSQHGRDQPRLSQ*SLL*K

Frame 2

ERHGRGGAGGGLRARPDGSSPEKDPAARVPSSG FPNPGDSAPGRCYGRHFHSVPGGQRSRRSPVAG QHGERPQPGLLQYKADINAVNEHGNVPLHYACF WGQDQVAEDLVANGALVSICNKYGEMPVDKAKAP LRELLRERAEKMGQNLNRIPYKDTFWKGTTRTR PRNGTLNKHSGIDFKQLNFLTKLNENHSGELWK GRWQGNDIVVKVLKVRDWSTRKSRDFNEECPRLR IFSHPNVLPVLGACQSPPAPHPTLITHWMPYGS LYNVLHEGTNFVVDQSQAVKFALDMARGMAFLH TLEPLIPRHALNSRSVMIDEDMTARISMADVKFS FQCPGRMYAPAWVAPEGE*SHHVGR*KRTTSEV VEGGRDRTGKGARTDKPYLSSSAEEA*RHKQTL SRHVEFCSASVGTGDTGGTLC*PLQYGDWNEGES TTAYICVAGVVGDGENNCSGPWLLTYLFGYTVI LSQGPVASLYMTDSNCEAAFFLVFAGGIGRPSA YHPTRYFPSCV*AHEDLHE*RPCKATQI*HDCAY P*EDAGQVGLEGPCLNSRGVGTWLGECTSPKQQ ASGCLPRLQSWYYPSHGVHPLPPSLPLWPQEGR AQSFVTCHMVSPNMGGISPACHNKVYYEN

Sequence ILK.cAug05

ILK.F11 (forward primer)
ILK.R12 (reverse primer)
Alternative acceptor

Frame 0

KSATGGAGPAAGCGRGRTGVPRRRILQPESRPQ ASPIQGTRRRDAAMDDIFTQCREGNAVAVRLWLD NTENDLNQGDDHGFSPLHWACREGRSAVVEMLI MRGARINVMNRGDDTPLHLAASHGHRDIVQKLL QYKADINAVNEHGNVPLHYACFWGQDQVAEDLVA NGALVSICNKYGEMPVDKAKAPLRELLRERAEK MGQNLNRIPYKDTFWKGTTRTRPRNGTLNKHSG IDFKQLNFLTKLNENHSGELWKGRWQGNDIVVKV LKVRDWSTRKSRDFNEECPRLRIFSHPNVLPVL GACQSPPAPHPTLITHWMPYGSLYNVLHEGTNF VVDQSQAVKFALDMARGMAFLHTLEPLIPRHALN SRSVMIDEDMTARISMADVKFSFQCPGRMYAPA WVAPEALQKKPEDTNRRSADMWSFAVLLWELVT REVPFADLSNMEIGMKVALEGLRPTIPPGISPHV CKLMKICMNEDPAKRPKFDMIVPILEKMQDK*D WKVLA*TPEVSGHGWGNAPPQSSRPLVASPASS HGTTPAMGSIPFPHPYHCGPKRGGLRALSLATWC LPTWEGSAPPVTIKFIMKTG

Frame 1

RAPRAGRGRRRAAGAAGREFPGEGSCSPSPVLR LPQSRGLGAGTLLWTTFSLSAGRATQSPFACGW TTRRTTSTRGTIMASPPCTGPAERAALLWLRC*S CGGHGSM**TVGMTPPCIWQPVMDTVILYRSYC STRQTSMQ*MNTGMCPCTMPVFGAKIKWQRTWW QMGPLSASVTSMERCLWTKPRHP*ESFSESGQRR WARISTVFHTRTHSGRGPPALGPEMEP*TNTLA LTSNSLTS*RSSTRITLESYGRAAGRAMTLS*R C*RFETGVQGRAGTSMKSVPGSGFSRIQMCSQC* VPASLHLLLILLSSHTGCRMDPSTMYYMKAPIS SWTRARL*SLLWTWQGAWPSYTH*SPSSHDMHS IAVV**LMRT*LPELAWLMSSSLSNVLVACMHLP G*PPKLCRRSLKTQTDAQQTCGVLQCFCGNW*H GRYPLLTSPIWRLE*RWHWKAFGLPSHQVFPLM CVSS*RSA*MKTLQSDPNLT*LCLSLRRCRTSRT GRSLPELQRCRDMVGGMHLPKAAGLWLPPPPPV MVLPQPWGPSPSPIPTTVAPRGAGSELCHLPHG VSQHGRDQPRLSQ*SLL*KQA

Frame 2

ERHGRGGAGGGLRARPDGSSPEKDPAARVPSSG FPNPGDSAPGRCYGRHFHSVPGGQRSRRSPVAG QHGERPQPGGRSWLLPLALGLPRGPLCCG*DVD HAGGTDQCNEPWG*HPPASGSQSWTP*YCTEAIA VQGRHQCSE*TRECAPALCLFLGPRSSGRGPGG KWGPCQHL*QVWRDACGQSQGTPERASPRAGRE DGPESQPYSIQGHILEGDHPHSAPKWNPEQTLWH *LQTA*LPDEAQRESLWRAMEGPLAGQ*HCREG AEGSRLEYKEEQGLQ*RVSPAQDFLASKCAPSA RCLPVSTCSSSYSHHTLDAVWIPLQCTT*RHQFR RGPEPGCEVCFGHGKGHGLPTHTRAPHPTTCTQ *P*CND**GHDCPN*HG*CQVLFPMSWSHVCTC LGSPRSSAEEA*RHKQTLSRHVEFCSASVGTGDT GGTLC*PLQYGDWNEGGIGRPSAYHPTRYFPSC V*AHEDLHE*RPCKATQI*HDCAYP*EDAGQVG LEGPCLNSRGVGTWLGECTSPKQQASGCLPRLQS WYYPSHGVHPLPPSLPLWPQEGRAQSFVTCHMV SPNMGGISPACHNKVYYENRL

Sequence ILK.bAug05

AAGAGCGCCACGGGCGGGGCGGGGCCGGCGGCGGGCTGCGGGCGCGGCCGGACGGGAGTTCCCCGGAGAAGGATCCTGCAGCCCGAGTCCCGAGGATAAA GCTTGGGGTTCATCCTCCTTCCCTGGATCACTCCACAGTCCTCAGGCTTCCCCAATCCAGGGGACTCGGCGCCGGGACGCTGCTATGGACGACATTTTCA CTCAGTGCCGGGAGGGCAACGCAGTCGCCGTTCGCCTGTGGCTGGACAACACGGAGAACGACCTCAACCAGGGGGACGATCATGGCTTCTCCCCCTTGCA CTGGGCCTGCCGAGAGGGCCGCTCTGCTGTGGTTGAGATGTTGATCATGCGGGGGGCACGGATCAATGTAATGAACCGTGGGGATGACACCCCCCTGCAT CTGGCAGCCAGTCATGGACACCGTGATATTGTACAGAAGCTATTGCAGTACAAGGCAGACATCAATGCAGTGAATGAACACGGGAATGTGCCCCTGCACT ATGCCTGTTTTTGGGGCCAAGATCAAGTGGCAGAGGACCTGGTGGCAAATGGGGCCCTTGTCAGCATCTGTAACAAGTATGGAGAGATGCCTGTGGACAA AGCCAAGGCACCCCTGAGAGAGCTTCTCCGAGAGCGGGCAGAGAAGATGGGCCAGAATCTCAACCGTATTCCATACAAGGACACATTCTGGAAGGGGACC ACCCGCACTCGGCCCCGAAATGGAACCCTGAACAAACACTCTGGCATTGACTTCAAACAGCTTAACTTCCTGACGAAGCTCAACGAGAATCACTCTGGAG AGCTATGGAAGGGCCGCTGGCAGGGCAATGACATTGTCGTGAAGGTGCTGAAGGTTCGAGACTGGAGTACAAGGAAGAGCAGGGACTTCAATGAAGAGTG TCCCCGGCTCAGGATTTTCTCGCATCCAAATGTGCTCCCAGTGCTAGGTGCCTGCCAGTCTCCACCTGCTCCTCATCCTACTCTCATCACACACTGGATG CCGTATGGATCCCTCTACAATGTACTACATGAAGGCACCAATTTCGTCGTGGACCAGAGCCAGGCTGTGAAGTTTGCTTTGGACATGGCAAGGGGCATGG CCTTCCTACACACACTAGAGCCCCTCATCCCACGACATGCACTCAATAGCCGTAGTGTAATGATTGATGAGGACATGACTGCCCGAATTAGCATGGCTGA TGTCAAGTTCTCTTTCCAATGTCCTGGTCGCATGTATGCACCTGCCTGGGTAGCCCCCGAAGCTCTGCAGAAGAAGCCTGAAGACACAAACAGACGCTCA GCAGACATGTGGAGTTTTGCAGTGCTTCTGTGGGAACTGGTGACACGGGAGGTACCCTTTGCTGACCTCTCCAATATGGAGATTGGAATGAAGGTGGCAT TGGAAGGCCTTCGGCCTACCATCCCACCAGGTATTTCCCCTCATGTGTGTAAGCTCATGAAGATCTGCATGAATGAAGACCCTGCAAAGCGACCCAAATT TGACATGATTGTGCCTATCCTTGAGAAGATGCAGGACAAGTAGGACTGGAAGGTCCTTGCCTGAACTCCAGAGGTGTCGGGACATGGTTGGGGGAATGCA CCTCCCCAAAGCAGCAGGCCTCTGGTTGCCTCCCCCGCCTCCAGTCATGGTACTACCCCAGCCATGGGGTCCATCCCCTTCCCCCATCCCTACCACTGTG GCCCCAAGAGGGGCGGGCTCAGAGCTTTGTCACTTGCCACATGGTGTCTCCCAACATGGGAGGGATCAGCCCCGCCTGTCACAATAAAGTTTATTATGAA AACAGGCTG

ILK.F11 (forward primer)
ILK.R12 (reverse primer)
Alternative acceptor

Frame 0

KSATGGAGPAAGCGRGRTGVPRRRILQPESRG* SLGFILLPWITPQSSGFPNPGDSAPGRCYGRHFH SVPGGQRSRRSPVAGQHGERPQPGGRSWLLPLA LGLPRGPLCCG*DVDHAGGTDQCNEPWG*HPPA SGSQSWTP*YCTEAIAVQGRHQCSE*TRECAPAL CLFLGPRSSGRGPGGKWGPCQHL*QVWRDACGQ SQGTPERASPRAGREDGPESQPYSIQGHILEGD HPHSAPKWNPEQTLWH*LQTA*LPDEAQRESLWR AMEGPLAGQ*HCREGAEGSRLEYKEEQGLQ*RV SPAQDFLASKCAPSARCLPVSTCSSSYSHHTLD AVWIPLQCTT*RHQFRRGPEPGCEVCFGHGKGHG LPTHTRAPHPTTCTQ*P*CND**GHDCPN*HG* CQVLFPMSWSHVCTCLGSPRSSAEEA*RHKQTL SRHVEFCSASVGTGDTGGTLC*PLQYGDWNEGGI GRPSAYHPTRYFPSCV*AHEDLHE*RPCKATQI *HDCAYP*EDAGQVGLEGPCLNSRGVGTWLGEC TSPKQQASGCLPRLQSWYYPSHGVHPLPPSLPLW PQEGRAQSFVTCHMVSPNMGGISPACHNKVYYE NRL

Frame 1

RAPRAGRGRRRAAGAAGREFPGEGSCSPSPEDK AWGSSSFPGSLHSPQASPIQGTRRRDAAMDDIF TQCREGNAVAVRLWLDNTENDLNQGDDHGFSPLH WACREGRSAVVEMLIMRGARINVMNRGDDTPLH LAASHGHRDIVQKLLQYKADINAVNEHGNVPLH YACFWGQDQVAEDLVANGALVSICNKYGEMPVDK AKAPLRELLRERAEKMGQNLNRIPYKDTFWKGT TRTRPRNGTLNKHSGIDFKQLNFLTKLNENHSG ELWKGRWQGNDIVVKVLKVRDWSTRKSRDFNEEC PRLRIFSHPNVLPVLGACQSPPAPHPTLITHWM PYGSLYNVLHEGTNFVVDQSQAVKFALDMARGM AFLHTLEPLIPRHALNSRSVMIDEDMTARISMAD VKFSFQCPGRMYAPAWVAPEALQKKPEDTNRRS ADMWSFAVLLWELVTREVPFADLSNMEIGMKVA LEGLRPTIPPGISPHVCKLMKICMNEDPAKRPKF DMIVPILEKMQDK*DWKVLA*TPEVSGHGWGNA PPQSSRPLVASPASSHGTTPAMGSIPFPHPYHC GPKRGGLRALSLATWCLPTWEGSAPPVTIKFIMK TG

Frame 2

ERHGRGGAGGGLRARPDGSSPEKDPAARVPRIK LGVHPPSLDHSTVLRLPQSRGLGAGTLLWTTFS LSAGRATQSPFACGWTTRRTTSTRGTIMASPPC TGPAERAALLWLRC*SCGGHGSM**TVGMTPPCI WQPVMDTVILYRSYCSTRQTSMQ*MNTGMCPCT MPVFGAKIKWQRTWWQMGPLSASVTSMERCLWT KPRHP*ESFSESGQRRWARISTVFHTRTHSGRGP PALGPEMEP*TNTLALTSNSLTS*RSSTRITLE SYGRAAGRAMTLS*RC*RFETGVQGRAGTSMKS VPGSGFSRIQMCSQC*VPASLHLLLILLSSHTGC RMDPSTMYYMKAPISSWTRARL*SLLWTWQGAW PSYTH*SPSSHDMHSIAVV**LMRT*LPELAWL MSSSLSNVLVACMHLPG*PPKLCRRSLKTQTDAQ QTCGVLQCFCGNW*HGRYPLLTSPIWRLE*RWH WKAFGLPSHQVFPLMCVSS*RSA*MKTLQSDPN LT*LCLSLRRCRTSRTGRSLPELQRCRDMVGGMH LPKAAGLWLPPPPPVMVLPQPWGPSPSPIPTTV APRGAGSELCHLPHGVSQHGRDQPRLSQ*SLL* KQA

Sequence ILK.aAug05

ILK.F11 (forward primer)
ILK.R12 (reverse primer)
Alternative acceptor

Frame 0

SPSPGECERTRAPCHPSLLLSPK*GTEPTLGRT PGPLSQSIRSLNLPTSPNSVRG*GLVACSRTSVQ QTLPLRHPLPTLTRLYLASRGHSQGSSRSPELL HRPPLAGDAAQAPYPQHKHFSPVEDKAWGSSSF PGSLHSPQASPIQGTRRRDAAMDDIFTQCREGNA VAVRLWLDNTENDLNQGDDHGFSPLHWACREGR SAVVEMLIMRGARINVMNRGDDTPLHLAASHGH RDIVQKLLQYKADINAVNEHGNVPLHYACFWGQD QVAEDLVANGALVSICNKYGEMPVDKAKAPLRE LLRERAEKMGQNLNRIPYKDTFWKGTTRTRPRN GTLNKHSGIDFKQLNFLTKLNENHSGELWKGRWQ GNDIVVKVLKVRDWSTRKSRDFNEECPRLRIFS HPNVLPVLGACQSPPAPHPTLITHWMPYGSLYN VLHEGTNFVVDQSQAVKFALDMARGMAFLHTLEP LIPRHALNSRSVMIDEDMTARISMADVKFSFQC PGRMYAPAWVAPEALQKKPEDTNRRSADMWSFA VLLWELVTREVPFADLSNMEIGMKVALEGLRPTI PPGISPHVCKLMKICMNEDPAKRPKFDMIVPIL EKMQDK*DWKVLA*TPEVSGHGWGNAPPQSSRP LVASPASSHGTTPAMGSIPFPHPYHCGPKRGGLR ALSLATWCLPTWEGSAPPVTIKFIMKTG

Frame 1

ARVPVSARGPAPPVTPHFS*VPSKERSQPWGGP PVPSPRVYGA*TSPLPPTLFADRV*LPALGHPF SRHYLFVTPCPP*PAFTSRLEDTARDHPAAPNSF TDPH*PGTQLRPPTPNTNTSLL*RIKLGVHPPS LDHSTVLRLPQSRGLGAGTLLWTTFSLSAGRAT QSPFACGWTTRRTTSTRGTIMASPPCTGPAERAA LLWLRC*SCGGHGSM**TVGMTPPCIWQPVMDT VILYRSYCSTRQTSMQ*MNTGMCPCTMPVFGAK IKWQRTWWQMGPLSASVTSMERCLWTKPRHP*ES FSESGQRRWARISTVFHTRTHSGRGPPALGPEM EP*TNTLALTSNSLTS*RSSTRITLESYGRAAG RAMTLS*RC*RFETGVQGRAGTSMKSVPGSGFSR IQMCSQC*VPASLHLLLILLSSHTGCRMDPSTM YYMKAPISSWTRARL*SLLWTWQGAWPSYTH*S PSSHDMHSIAVV**LMRT*LPELAWLMSSSLSNV LVACMHLPG*PPKLCRRSLKTQTDAQQTCGVLQ CFCGNW*HGRYPLLTSPIWRLE*RWHWKAFGLP SHQVFPLMCVSS*RSA*MKTLQSDPNLT*LCLSL RRCRTSRTGRSLPELQRCRDMVGGMHLPKAAGL WLPPPPPVMVLPQPWGPSPSPIPTTVAPRGAGS ELCHLPHGVSQHGRDQPRLSQ*SLL*KQA

Frame 2

PESR*VREDPRPLSPLTSPESQVRNGANPGEDP RSPLPEYTEPEPPHFPQLCSRIGSSCLLSDIRS ADTTSSSPPAHPDPPLPRV*RTQPGIIPQPRTP SQTPTSRGRSSGPLPPTQTLLSCRG*SLGFILLP WITPQSSGFPNPGDSAPGRCYGRHFHSVPGGQR SRRSPVAGQHGERPQPGGRSWLLPLALGLPRGP LCCG*DVDHAGGTDQCNEPWG*HPPASGSQSWTP *YCTEAIAVQGRHQCSE*TRECAPALCLFLGPR SSGRGPGGKWGPCQHL*QVWRDACGQSQGTPER ASPRAGREDGPESQPYSIQGHILEGDHPHSAPKW NPEQTLWH*LQTA*LPDEAQRESLWRAMEGPLA GQ*HCREGAEGSRLEYKEEQGLQ*RVSPAQDFL ASKCAPSARCLPVSTCSSSYSHHTLDAVWIPLQC TT*RHQFRRGPEPGCEVCFGHGKGHGLPTHTRA PHPTTCTQ*P*CND**GHDCPN*HG*CQVLFPM SWSHVCTCLGSPRSSAEEA*RHKQTLSRHVEFCS ASVGTGDTGGTLC*PLQYGDWNEGGIGRPSAYH PTRYFPSCV*AHEDLHE*RPCKATQI*HDCAYP *EDAGQVGLEGPCLNSRGVGTWLGECTSPKQQAS GCLPRLQSWYYPSHGVHPLPPSLPLWPQEGRAQ SFVTCHMVSPNMGGISPACHNKVYYENRL