Back to Rnomics Platform
 Open Session
×
1 warning:
  • Access restricted to public data.
    Please sign in at Rnomics Platform to access your data.
Navigation
Home
Sequences

Sequence ETS1.dAug05

CCTTGTCAAGGGCTAAAGCTGTTTAGTAGTGGACAAGGTTAAAAATGCAAGCTTTTCTGATTTAAAGTATTTTCCCTTATTCTCTAAGGAGCTTGTCCCA
CATCATAGGGCCCTGTAGATGGTGAAAACTGCTTATTTTAGGTACAAATCTCTCCTCTCTTTACTTGCAAACCCTTTGTTTCCAGGCTATGGTATTGAGC
ATGCCCAGTGTGTTCCACCATCGGAGTTCTCAGAGCCCAGCTTCATCACAGAGTCCTATCAGACGCTCCATCCCATCAGCTCGGAAGAGCTCCTCTCCCT
CAAGTATGAGAATGACTACCCCTCGGTCATTCTCCGAGACCCTCTCCAGACAGACACCTTGCAGAATGACTACTTTGCTATCAAACAAGAAGTCGTCACC
CCAGACAACATGTGCATGGGGAGGACCAGTCGTGGCAGTGGACCAATCCAGCTATGGCAGTTTCTTCTGGAATTACTCACTGATAAATCCTGTCAGTCTT
TTATCAGCTGGACAGGAGATGGCTGGGAATTCAAACTTTCTGACCCAGATGAGGTGGCCAGGAGATGGGGAAAGAGGAAAAACAAACCTAAGATGAATTA
TGAGAAACTGAGCCGTGGCCTACGCTACTATTACGACAAAAACATCATCCACAAGACAGCGGGGAAACGCTACGTGTACCGCTTTGTGTGTGACCTGCAG
AGCCTGCTGGGGTACACCCCTGAGGAGCTGCACGCCATGCTGGACGTCAAGCCAGATGCCGACGAGTGATGGCACTGAAGGGGCTGGGGAAACCCTGCTG
AGACCTTCCAAGGACAGCCGTGTTGGTTGGACTCTGAATTTTGAATTGTTATTCTATTTTTTATTTTCCAGAACTCATTTTTTACCTTCAGGGGTGGGAG
CTAAGTCAGTTGCAGCTGTAATCAATTGTGCGCAGTTGGGAAAGGAAAGCCAGGACTTGTGGGGTGGGTGGGACCAGAAATTCTTGAGCAAATTTTCAGG
AGAGGGAGAAGGGCCTTCTCAGAAGCTTGAAGGCTCTGGCTTAACAGAGAAAGAGACTAATGTGTCCAATCATTTTTAAAAATCATCCATGAAAAAGTGT
CTTGAGTTGTGGACCCATTAGCAAGTGACATTGTCACATCAGAACTCATGAAACTGATGTAAGGCAATTAATTTGCTTCTGTTTTTAGGTCTGGGAGGGC
AAAAAAGAGGTGGGTGGGATGAAACATGTTTTGGGGGGGGATGCACTGAAAATCTGAGAACTATTTACCTATCACTCTAGTTTTGAAGCAAAGATGGACT
TCAGTGGGGAGGGGCCAAAACCGTTGTTGTGTTAAAATTTATTTTATTAAATTTTGTGCCAGTATTTTTTTTCTTAAAAATCGTCTTAAGCTCTAAGGTG
GTCTCAGTATTGCAATATCATGTAAGTTTGTTTTTATTTGCCGGCTGAGGATTCTGTCACAATGAAAGAAAACTGTTTATATAGACCCCATTGGAAAAGC
AAAACGCTCTCACTGAGATCAGGGATCCCAAATTCATGGGACTTATATAAGAAGGACAATTAATGCTGATTTGGGTACAGGGGAATTATGTGTGTGAATG
TCATCTACAATTAAAAAAAATTAGCACATCCCTTTACTTACTTGTTATCAGTGGATTCTCGGGGTTTGGACTTAATGTTGAGCTAAGAAGCATTAAGTCT
TTGAACTGAATGTATTTTGCATCCCTGGTTTTGGACGACAGTAAACGTAGGAGCACTGTTGAAGTCCTGGAAGGGAGATCGAAGGAGGAAGATTGACTTG
GTTCTTTCTTAGTCCTATATCTGTAGCATAGATGACTTGGAATAAAAGCTGTATGCATGGGCATTACCCCTCAGGTCCTAAGAAATAAGTCCTGAATGCA
TGTCGTTCCAAACTAACACTCTGTAATTTTTCTTTTATGTCTTATTTTCCAAGAGTCCTCCATTTTTTGCACCCCCTCACCGCCAACTCTGTTATTCAGT
AGAGAGAAGTGTACGGCTTTCTGATTGGTGAGTGAAAAAGTAACTTGAGACACGACCTAAGTTGAAGAGTTTAGACTTGCTGAGTTTTAGAAGTGATGGA
AATTAAGAGAGCATTTCAATAAAATGTGACTTGGCTGTCTTTGGAAGAGAAGTGCAAGGCTTTCCTTTGAAGAATTTAAATTAGTCCGGTAGGATGTCAG
GTGAGACTGTGTATGCAAAATGAATGGCACAGGTGATGCCAGGGCCTCTTGCTTGGGTCTGATGTCTTGGCACAGGGTAAGTGAAGGTTAATTCCAGAAG
AGAGGAATGACTTGAAGGCAAAGGAAACTAAGGAAGGAGGTTCAGTGAGGAAAATAAGGTTGTCCATGAGATTTGAATAGATTTTTAGTTCCCCCAAGGT
TTAAATACAAACATAGTCAAGCAAGGTAGTCATCTTTCTGCTGGTTGTGAGGGGGAATCTGAAAATGGAGTTTTAGAGGAAAAGTCAACATCTAACTAGT
GAGGAAAAGTGCCTAATACAATTAGAATCTCCCTCACTCTATAGTTGCCCAGTTGAAAGGATAAGGAGGAGGGGTGGCTTTTATGGACTTCCATGAGAGA
AGGAAAGAAATATTTCAGGTAAGCTTCTCAGGGCTGGCCCTTTTTGGGATTTGGATGAGAAATTGGAAGTACTAACTACTTTCTAGCATATCTTTAAGAA
AATTGATTGTTATTTACTCCCAGATCCTCTTGCAGACCCAGAATTATCAGGAACATAGCTCTGTGATTCATGAGTGTCCCCATACTGATGAATTGGAGCA
TCCATATGGAAAGCAAAGGCAGAATTATCCCAGCTGTATTATTTTGATCTTTTGGATGCAGGTGCCTTAATGAAGCTCTCAAAATATTTTAGGAGCTGCT
CAGGGAGTGTTGGGTGGAACTGTTTGGACTACATTGTTTTCTCTTAGATTATGTGATTTTTGTTGGGCACTGGCAAAAGGTGTGTGTGTGAATGTGTGCA
TGTGTGTGAATGTTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTTTGCAGACATGCAAAACTGCAGCTGAAATAATACCTTAGATT
TCTAGGTAAGTCTTTCCACATTTCAATAATGGGTAAGAGTAGAACCAGGGCCGGGTATCAATTATTGCTTGCTGTTTGCAACCAGGCATAAAATCACTTT
CTCAAATCATCCACCGTTCCTATTAAATTTATGCCGGAAACTCTCCTTCTGTGAGTATAACTCCTGCAGTTCCTATAGCAGATAAGATATAAGAAAGTGC
CTCCTAGTGCTCCTCCGCCCGCTTGTTTGCTAAAATTCCCTTTCTCTCTAAGTCCACCATTTTCAAGATTTGTAGATAGTGTATTAGTTAAGACAGCTTT
GTCGATCTGGCCAGATGTTTTTTCTCCTTTGTCCAAAGGCCAGAGACCATCCCAGGAAGAGTGGTGGGTGGTTTATACACTGGAAATGTTGCGTTTATGC
TTTTTAAAAACACACGTTAACTTCAGAGGAAGGATGGGCAAATCTGGTCTAGCTGGGTGAAACCCTTATTTTCCCAGAGATGCCTTAACCTTTGTTGGTT
TTGGCTTTAGGGTTCAGAGTCACTTTTGTTCCCTTCTCCATTCTGGAGAGGGACTTCCCCTACATAGAGCCCTGATTTTTGTGGCTGTGGGGATTGGAGG
TAGCATTCAAAGATCAGATGTGCTTTTCCTCACTTTGGAGATGAACACTCTGGGTTTTACAGCATTAACCTGCCTAACCTTCATGGTGAGAAATACACCA
TCTCTCTTCTAGTCATGCTGTGCATGCCGCTTACTCTGTTGGGGTCTATATAAATTTGTTGAACTCTTACCTACATTCCAAAGAAGTTTCAAGGAACCAT
AAATATATGTATACATATACATATATAAAATATATATATTAAAATAAAATTATCAGGAATACTGCCTCAGTTATTGAACTTTTTTTTTTAAGAATACTTT
TTTTTTAAGCTGAGAAGTATAGGGATGAAAAAGATGTTATATTGTGTTTGACTATTTTCCAACTTGTATTTTCATATAATTTATATTTTTTAAAAGCTGA
AAATTTAGAAGCAAGATGAAAAAAAGGAAAAGCAGGTGCTTTTTAAAAATCAGAACTGAGGTAGCTTAGAGATGTAGCGATGTAAGTGTCGATGTTTTTT
TAAAAAAAAATGCAAAAAAATTCTTATGGCGGAGTTTTTTGTTTGTTTATTTTAGTAGCTGATGCTGGCACATCATTTTGCTGGAGAGTTTTTTATATAC
TGTAGCCTGATTTCATATTGTATTTTAAACTGTGTGAAATTAAAAACAAAGAATTTCATTCATAATGCT
  • ETS1.u.f.12 (forward primer)
  • ETS1.u.r.14 (reverse primer)
  • Single exon skipping

Frame 0

PCQGLKLFSSGQG*KCKLF*FKVFSLIL*GACP
TS*GPVDGENCLF*VQISPLFTCKPFVSRLWY*A
CPVCSTIGVLRAQLHHRVLSDAPSHQLGRAPLP
QV*E*LPLGHSPRPSPDRHLAE*LLCYQTRSRH
PRQHVHGEDQSWQWTNPAMAVSSGITH**ILSVF
YQLDRRWLGIQTF*PR*GGQEMGKEEKQT*DEL
*ETEPWPTLLLRQKHHPQDSGETLRVPLCV*PA
EPAGVHP*GAARHAGRQARCRRVMALKGLGKPC*
DLPRTAVLVGL*ILNCYSIFYFPELIFYLQGWE
LSQLQL*SIVRSWERKARTCGVGGTRNS*ANFQ
EREKGLLRSLKALA*QRKRLMCPIIFKNHP*KSV
LSCGPISK*HCHIRTHETDVRQLICFCF*VWEG
KKEVGGMKHVLGGDALKI*ELFTYHSSFEAKMD
FSGEGPKPLLC*NLFY*ILCQYFFS*KSS*ALRW
SQYCNIM*VCFYLPAEDSVTMKENCLYRPHWKS
KTLSLRSGIPNSWDLYKKDN*C*FGYRGIMCVN
VIYN*KKLAHPFTYLLSVDSRGLDLMLS*EALSL
*TECILHPWFWTTVNVGALLKSWKGDRRRKIDL
VLS*SYICSIDDLE*KLYAWALPLRS*EISPEC
MSFQTNTL*FFFYVLFSKSPPFFAPPHRQLCYSV
ERSVRLSDW*VKK*LETRPKLKSLDLLSFRSDG
N*ESISIKCDLAVFGREVQGFPLKNLN*SGRMS
GETVYAK*MAQVMPGPLAWV*CLGTG*VKVNSRR
EE*LEGKGN*GRRFSEENKVVHEI*IDF*FPQG
LNTNIVKQGSHLSAGCEGESENGVLEEKSTSN*
*GKVPNTIRISLTL*LPS*KDKEEGWLLWTSMRE
GKKYFR*ASQGWPFLGFG*EIGSTNYFLAYL*E
N*LLFTPRSSCRPRIIRNIAL*FMSVPILMNWS
IHMESKGRIIPAVLF*SFGCRCLNEALKIF*ELL
RECWVELFGLHCFLLDYVIFVGHWQKVCV*MCA
CV*MLCVCVCVCVCVCVCVFADMQNCS*NNTLD
F*VSLSTFQ*WVRVEPGPGINYCLLFATRHKITF
SNHPPFLLNLCRKLSFCEYNSCSSYSR*DIRKC
LLVLLRPLVC*NSLSL*VHHFQDL*IVY*LRQL
CRSGQMFFLLCPKARDHPRKSGGWFIHWKCCVYA
F*KHTLTSEEGWANLV*LGETLIFPEMP*PLLV
LALGFRVTFVPFSILERDFPYIEP*FLWLWGLE
VAFKDQMCFSSLWR*TLWVLQH*PA*PSW*EIHH
LSSSHAVHAAYSVGVYINLLNSYLHSKEVSRNH
KYMYTYTYIKYIY*NKIIRNTASVIELFFLRIL
FF*AEKYRDEKDVILCLTIFQLVFSYNLYFLKAE
NLEAR*KKGKAGAF*KSELR*LRDVAM*VSMFF
*KKMQKNSYGGVFCLFILVADAGTSFCWRVFYI
L*PDFILYFKLCEIKNKEFHS*C

Frame 1

LVKG*SCLVVDKVKNASFSDLKYFPLFSKELVP
HHRAL*MVKTAYFRYKSLLSLLANPLFPGYGIE
HAQCVPPSEFSEPSFITESYQTLHPISSEELLSL
KYENDYPSVILRDPLQTDTLQNDYFAIKQEVVT
PDNMCMGRTSRGSGPIQLWQFLLELLTDKSCQS
FISWTGDGWEFKLSDPDEVARRWGKRKNKPKMNY
EKLSRGLRYYYDKNIIHKTAGKRYVYRFVCDLQ
SLLGYTPEELHAMLDVKPDADE*WH*RGWGNPA
ETFQGQPCWLDSEF*IVILFFIFQNSFFTFRGGS
*VSCSCNQLCAVGKGKPGLVGWVGPEILEQIFR
RGRRAFSEA*RLWLNRERD*CVQSFLKIIHEKV
S*VVDPLASDIVTSELMKLM*GN*FASVFRSGRA
KKRWVG*NMFWGGMH*KSENYLPITLVLKQRWT
SVGRGQNRCCVKIYFIKFCASIFFLKNRLKL*G
GLSIAISCKFVFICRLRILSQ*KKTVYIDPIGKA
KRSH*DQGSQIHGTYIRRTINADLGTGELCV*M
SSTIKKN*HIPLLTCYQWILGVWT*C*AKKH*V
FELNVFCIPGFGRQ*T*EHC*SPGREIEGGRLTW
FFLSPISVA*MTWNKSCMHGHYPSGPKK*VLNA
CRSKLTLCNFSFMSYFPRVLHFLHPLTANSVIQ
*REVYGFLIGE*KSNLRHDLS*RV*TC*VLEVME
IKRAFQ*NVTWLSLEEKCKAFL*RI*ISPVGCQ
VRLCMQNEWHR*CQGLLLGSDVLAQGK*RLIPE
ERNDLKAKETKEGGSVRKIRLSMRFE*IFSSPKV
*IQT*SSKVVIFLLVVRGNLKMEF*RKSQHLTS
EEKCLIQLESPSLYSCPVERIRRRGGFYGLP*E
KERNISGKLLRAGPFWDLDEKLEVLTTF*HIFKK
IDCYLLPDPLADPELSGT*LCDS*VSPY**IGA
SIWKAKAELSQLYYFDLLDAGALMKLSKYFRSC
SGSVGWNCLDYIVFS*IM*FLLGTGKRCVCECVH
VCECCVCVCVCVCVCVCVCLQTCKTAAEIIP*I
SR*VFPHFNNG*E*NQGRVSIIACCLQPGIKSL
SQIIHRSY*IYAGNSPSVSITPAVPIADKI*ESA
S*CSSARLFAKIPFLSKSTIFKICR*CIS*DSF
VDLARCFFSFVQRPETIPGRVVGGLYTGNVAFM
LFKNTR*LQRKDGQIWSSWVKPLFSQRCLNLCWF
WL*GSESLLFPSPFWRGTSPT*SPDFCGCGDWR
*HSKIRCAFPHFGDEHSGFYSINLPNLHGEKYT
ISLLVMLCMPLTLLGSI*IC*TLTYIPKKFQGTI
NICIHIHI*NIYIKIKLSGILPQLLNFFF*EYF
FFKLRSIGMKKMLYCV*LFSNLYFHIIYIF*KL
KI*KQDEKKEKQVLFKNQN*GSLEM*RCKCRCFF
KKKCKKILMAEFFVCLF**LMLAHHFAGEFFIY
CSLISYCILNCVKLKTKNFIHNA

Frame 2

LSRAKAV**WTRLKMQAFLI*SIFPYSLRSLSH
IIGPCRW*KLLILGTNLSSLYLQTLCFQAMVLS
MPSVFHHRSSQSPASSQSPIRRSIPSARKSSSP
SSMRMTTPRSFSETLSRQTPCRMTTLLSNKKSSP
QTTCAWGGPVVAVDQSSYGSFFWNYSLINPVSL
LSAGQEMAGNSNFLTQMRWPGDGERGKTNLR*I
MRN*AVAYATITTKTSSTRQRGNATCTALCVTCR
ACWGTPLRSCTPCWTSSQMPTSDGTEGAGETLL
RPSKDSRVGWTLNFELLFYFLFSRTHFLPSGVG
AKSVAAVINCAQLGKESQDLWGGWDQKFLSKFSG
EGEGPSQKLEGSGLTEKETNVSNHF*KSSMKKC
LELWTH*QVTLSHQNS*N*CKAINLLLFLGLGG
QKRGGWDETCFGGGCTENLRTIYLSL*F*SKDGL
QWGGAKTVVVLKFILLNFVPVFFFLKIVLSSKV
VSVLQYHVSLFLFAG*GFCHNERKLFI*TPLEK
QNALTEIRDPKFMGLI*EGQLMLIWVQGNYVCEC
HLQLKKISTSLYLLVISGFSGFGLNVELRSIKS
LN*MYFASLVLDDSKRRSTVEVLEGRSKEED*L
GSFLVLYL*HR*LGIKAVCMGITPQVLRNKS*MH
VVPN*HSVIFLLCLIFQESSIFCTPSPPTLLFS
REKCTAF*LVSEKVT*DTT*VEEFRLAEF*K*W
KLREHFNKM*LGCLWKRSARLSFEEFKLVR*DVR
*DCVCKMNGTGDARASCLGLMSWHRVSEG*FQK
RGMT*RQRKLRKEVQ*GK*GCP*DLNRFLVPPR
FKYKHSQAR*SSFCWL*GGI*KWSFRGKVNI*LV
RKSA*YN*NLPHSIVAQLKG*GGGVAFMDFHER
RKEIFQVSFSGLALFGIWMRNWKY*LLSSISLR
KLIVIYSQILLQTQNYQEHSSVIHECPHTDELEH
PYGKQRQNYPSCIILIFWMQVP**SSQNILGAA
QGVLGGTVWTTLFSLRLCDFCWALAKGVCVNVC
MCVNVVCVCVCVCVCVCVCVCRHAKLQLK*YLRF
LGKSFHISIMGKSRTRAGYQLLLAVCNQA*NHF
LKSSTVPIKFMPETLLL*V*LLQFL*QIRYKKV
PPSAPPPACLLKFPFSLSPPFSRFVDSVLVKTAL
SIWPDVFSPLSKGQRPSQEEWWVVYTLEMLRLC
FLKTHVNFRGRMGKSGLAG*NPYFPRDALTFVG
FGFRVQSHFCSLLHSGEGLPLHRALIFVAVGIGG
SIQRSDVLFLTLEMNTLGFTALTCLTFMVRNTP
SLF*SCCACRLLCWGLYKFVELLPTFQRSFKEP
*IYVYIYIYKIYILK*NYQEYCLSY*TFFFKNTF
FLS*EV*G*KRCYIVFDYFPTCIFI*FIFFKS*
KFRSKMKKRKSRCFLKIRTEVA*RCSDVSVDVF
LKKNAKKFLWRSFLFVYFSS*CWHIILLESFLYT
VA*FHIVF*TV*N*KQRISFIM

Sequence ETS1.bAug05

CGCGGCGCCGCGAGAAACGCCCTAAAGAGGAGGGGAGAGCGCGGGAGGGCGAGAGGGAGGGAGAGCGGCCGGGAGATCGAGAGCGAACGAGGCAGCCGCC
GGCGGAGAGGAGGGAGCGGGCGAGGGCCGGGCAGGAGGAGCGGGCGCGGCGCGGGCGAGGCTGGGACCCGAGCGCGCTCACTTCGCCGCAAAGTGCCAAC
TTCCCCTGGAGTGCCGGGCGCGCACCGTCCGGGCGCGGGGGAAAGAAAGGCAGCGGGAATTTGAGATTTTTGGGAAGAAAGTCGGATTTCCCCCGTCCCC
TTCCCCCTGTTACTAATCCTCATTAAAAAGAAAAACAACAGTAACTGCAAACTTGCTACCATCCCGTACGTCCCCCACTCCTGGCACCATGAAGGCGGCC
GTCGATCTCAAGCCGACTCTCACCATCATCAAGACGGAAAAAGTCGATCTGGAGCTTTTCCCCTCCCCGGATATGGAATGTGCAGATGTCCCACTATTAA
CTCCAAGCAGCAAAGAAATGATGTCTCAAGCATTAAAAGCTACTTTCAGTGGTTTCACTAAAGAACAGCAACGACTGGGGATCCCAAAAGACCCCCGGCA
GTGGACAGAAACCCATGTTCGGGACTGGGTGATGTGGGCTGTGAATGAATTCAGCCTGAAAGGTGTAGACTTCCAGAAGTTCTGTATGAATGGAGCAGCC
CTCTGCGCCCTGGGTAAAGACTGCTTTCTCGAGCTGGCCCCAGACTTTGTTGGGGACATCTTATGGGAACATCTAGAGATCCTGCAGAAAGAGGATGTGA
AACCATATCAAGTTAATGGAGTCAACCCAGCCTATCCAGAATCCCGCTATACCTCGGATTACTTCATTAGCTATGGTATTGAGCATGCCCAGTGTGTTCC
ACCATCGGAGTTCTCAGAGCCCAGCTTCATCACAGAGTCCTATCAGACGCTCCATCCCATCAGCTCGGAAGAGCTCCTCTCCCTCAAGTATGAGAATGAC
TACCCCTCGGTCATTCTCCGAGACCCTCTCCAGACAGACACCTTGCAGAATGACTACTTTGCTATCAAACAAGAAGTCGTCACCCCAGACAACATGTGCA
TGGGGAGGACCAGTCGTGGTAAACTCGGGGGCCAGGACTCTTTTGAAAGCATAGAGAGCTACGATAGTTGTGATCGCCTCACCCAGTCCTGGAGCAGCCA
GTCATCTTTCAACAGCCTGCAGCGTGTTCCCTCCTATGACAGCTTCGACTCAGAGGACTATCCGGCTGCCCTGCCCAACCACAAGCCCAAGGGCACCTTC
AAGGACTATGTGCGGGACCGTGCTGACCTCAATAAGGACAAGCCTGTCATTCCTGCTGCTGCCCTAGCTGGCTACACAGGCAGTGGACCAATCCAGCTAT
GGCAGTTTCTTCTGGAATTACTCACTGATAAATCCTGTCAGTCTTTTATCAGCTGGACAGGAGATGGCTGGGAATTCAAACTTTCTGACCCAGATGAGGT
GGCCAGGAGATGGGGAAAGAGGAAAAACAAACCTAAGATGAATTATGAGAAACTGAGCCGTGGCCTACGCTACTATTACGACAAAAACATCATCCACAAG
ACAGCGGGGAAACGCTACGTGTACCGCTTTGTGTGTGACCTGCAGAGCCTGCTGGGGTACACCCCTGAGGAGCTGCACGCCATGCTGGACGTCAAGCCAG
ATGCCGACGAGTGATGGCACTGAAGGGGCTGGGGAAACCCTGCTGAGACCTTCCAAGGACAGCCGTGTTGGTTGGACTCTGAATTTTGAATTGTTATTCT
ATTTTTTATTTTCCAGAACTCATTTTTTACCTTCAGGGGTGGGAGCTAAGTCAGTTGCAGCTGTAATCAATTGTGCGCAGTTGGGAAAGGAAAGCCAGGA
CTTGTGGGGTGGGTGGGACCAGAAATTCTTGAGCAAATTTTCAGGAGAGGGAGAAGGGCCTTCTCAGAAGCTTGAAGGCTCTGGCTTAACAGAGAAAGAG
ACTAATGTGTCCAATCATTTTTAAAAATCATCCATGAAAAAGTGTCTTGAGTTGTGGACCCATTAGCAAGTGACATTGTCACATCAGAACTCATGAAACT
GATGTAAGGCAATTAATTTGCTTCTGTTTTTAGGTCTGGGAGGGCAAAAAAGAGGTGGGTGGGATGAAACATGTTTTGGGGGGGGATGCACTGAAAATCT
GAGAACTATTTACCTATCACTCTAGTTTTGAAGCAAAGATGGACTTCAGTGGGGAGGGGCCAAAACCGTTGTTGTGTTAAAATTTATTTTATTAAATTTT
GTGCCAGTATTTTTTTTCTTAAAAATCGTCTTAAGCTCTAAGGTGGTCTCAGTATTGCAATATCATGTAAGTTTGTTTTTATTTGCCGGCTGAGGATTCT
GTCACAATGAAAGAAAACTGTTTATATAGACCCCATTGGAAAAGCAAAACGCTCTCACTGAGATCAGGGATCCCAAATTCATGGGACTTATATAAGAAGG
ACAATTAATGCTGATTTGGGTACAGGGGAATTATGTGTGTGAATGTCATCTACAATTAAAAAAAATTAGCACATCCCTTTACTTACTTGTTATCAGTGGA
TTCTCGGGGTTTGGACTTAATGTTGAGCTAAGAAGCATTAAGTCTTTGAACTGAATGTATTTTGCATCCCTGGTTTTGGACGACAGTAAACGTAGGAGCA
CTGTTGAAGTCCTGGAAGGGAGATCGAAGGAGGAAGATTGACTTGGTTCTTTCTTAGTCCTATATCTGTAGCATAGATGACTTGGAATAAAAGCTGTATG
CATGGGCATTACCCCTCAGGTCCTAAGAAATAAGTCCTGAATGCATGTCGTTCCAAACTAACACTCTGTAATTTTTCTTTTATGTCTTATTTTCCAAGAG
TCCTCCATTTTTTGCACCCCCTCACCGCCAACTCTGTTATTCAGTAGAGAGAAGTGTACGGCTTTCTGATTGGTGAGTGAAAAAGTAACTTGAGACACGA
CCTAAGTTGAAGAGTTTAGACTTGCTGAGTTTTAGAAGTGATGGAAATTAAGAGAGCATTTCAATAAAATGTGACTTGGCTGTCTTTGGAAGAGAAGTGC
AAGGCTTTCCTTTGAAGAATTTAAATTAGTCCGGTAGGATGTCAGGTGAGACTGTGTATGCAAAATGAATGGCACAGGTGATGCCAGGGCCTCTTGCTTG
GGTCTGATGTCTTGGCACAGGGTAAGTGAAGGTTAATTCCAGAAGAGAGGAATGACTTGAAGGCAAAGGAAACTAAGGAAGGAGGTTCAGTGAGGAAAAT
AAGGTTGTCCATGAGATTTGAATAGATTTTTAGTTCCCCCAAGGTTTAAATACAAACATAGTCAAGCAAGGTAGTCATCTTTCTGCTGGTTGTGAGGGGG
AATCTGAAAATGGAGTTTTAGAGGAAAAGTCAACATCTAACTAGTGAGGAAAAGTGCCTAATACAATTAGAATCTCCCTCACTCTATAGTTGCCCAGTTG
AAAGGATAAGGAGGAGGGGTGGCTTTTATGGACTTCCATGAGAGAAGGAAAGAAATATTTCAGGTAAGCTTCTCAGGGCTGGCCCTTTTTGGGATTTGGA
TGAGAAATTGGAAGTACTAACTACTTTCTAGCATATCTTTAAGAAAATTGATTGTTATTTACTCCCAGATCCTCTTGCAGACCCAGAATTATCAGGAACA
TAGCTCTGTGATTCATGAGTGTCCCCATACTGATGAATTGGAGCATCCATATGGAAAGCAAAGGCAGAATTATCCCAGCTGTATTATTTTGATCTTTTGG
ATGCAGGTGCCTTAATGAAGCTCTCAAAATATTTTAGGAGCTGCTCAGGGAGTGTTGGGTGGAACTGTTTGGACTACATTGTTTTCTCTTAGATTATGTG
ATTTTTGTTGGGCACTGGCAAAAGGTGTGTGTGTGAATGTGTGCATGTGTGTGAATGTTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTG
TGTTTGCAGACATGCAAAACTGCAGCTGAAATAATACCTTAGATTTCTAGGTAAGTCTTTCCACATTTCAATAATGGGTAAGAGTAGAACCAGGGCCGGG
TATCAATTATTGCTTGCTGTTTGCAACCAGGCATAAAATCACTTTCTCAAATCATCCACCGTTCCTATTAAATTTATGCCGGAAACTCTCCTTCTGTGAG
TATAACTCCTGCAGTTCCTATAGCAGATAAGATATAAGAAAGTGCCTCCTAGTGCTCCTCCGCCCGCTTGTTTGCTAAAATTCCCTTTCTCTCTAAGTCC
ACCATTTTCAAGATTTGTAGATAGTGTATTAGTTAAGACAGCTTTGTCGATCTGGCCAGATGTTTTTTCTCCTTTGTCCAAAGGCCAGAGACCATCCCAG
GAAGAGTGGTGGGTGGTTTATACACTGGAAATGTTGCGTTTATGCTTTTTAAAAACACACGTTAACTTCAGAGGAAGGATGGGCAAATCTGGTCTAGCTG
GGTGAAACCCTTATTTTCCCAGAGATGCCTTAACCTTTGTTGGTTTTGGCTTTAGGGTTCAGAGTCACTTTTGTTCCCTTCTCCATTCTGGAGAGGGACT
TCCCCTACATAGAGCCCTGATTTTTGTGGCTGTGGGGATTGGAGGTAGCATTCAAAGATCAGATGTGCTTTTCCTCACTTTGGAGATGAACACTCTGGGT
TTTACAGCATTAACCTGCCTAACCTTCATGGTGAGAAATACACCATCTCTCTTCTAGTCATGCTGTGCATGCCGCTTACTCTGTTGGGGTCTATATAAAT
TTGTTGAACTCTTACCTACATTCCAAAGAAGTTTCAAGGAACCATAAATATATGTATACATATACATATATAAAATATATATATTAAAATAAAATTATCA
GGAATACTGCCTCAGTTATTGAACTTTTTTTTTTAAGAATACTTTTTTTTTAAGCTGAGAAGTATAGGGATGAAAAAGATGTTATATTGTGTTTGACTAT
TTTCCAACTTGTATTTTCATATAATTTATATTTTTTAAAAGCTGAAAATTTAGAAGCAAGATGAAAAAAAGGAAAAGCAGGTGCTTTTTAAAAATCAGAA
CTGAGGTAGCTTAGAGATGTAGCGATGTAAGTGTCGATGTTTTTTTAAAAAAAAATGCAAAAAAATTCTTATGGCGGAGTTTTTTGTTTGTTTATTTTAG
TAGCTGATGCTGGCACATCATTTTGCTGGAGAGTTTTTTATATACTGTAGCCTGATTTCATATTGTATTTTAAACTGTGTGAAATTAAAAACAAAGAATT
TCATTCATAATGCT
  • ETS1.u.f.12 (forward primer)
  • ETS1.u.r.14 (reverse primer)
  • Single exon skipping

Frame 0

RGAARNALKRRGERGRARGRESGREIESERGSR
RRRGGSGRGPGRRSGRGAGEAGTRARSLRRKVPT
SPGVPGAHRPGAGERKAAGI*DFWEESRISPVP
FPLLLILIKKKNNSNCKLATIPYVPHSWHHEGG
RRSQADSHHHQDGKSRSGAFPLPGYGMCRCPTIN
SKQQRNDVSSIKSYFQWFH*RTATTGDPKRPPA
VDRNPCSGLGDVGCE*IQPERCRLPEVLYEWSS
PLRPG*RLLSRAGPRLCWGHLMGTSRDPAERGCE
TISS*WSQPSLSRIPLYLGLLH*LWY*ACPVCS
TIGVLRAQLHHRVLSDAPSHQLGRAPLPQV*E*
LPLGHSPRPSPDRHLAE*LLCYQTRSRHPRQHVH
GEDQSW*TRGPGLF*KHRELR*L*SPHPVLEQP
VIFQQPAACSLL*QLRLRGLSGCPAQPQAQGHL
QGLCAGPC*PQ*GQACHSCCCPSWLHRQWTNPAM
AVSSGITH**ILSVFYQLDRRWLGIQTF*PR*G
GQEMGKEEKQT*DEL*ETEPWPTLLLRQKHHPQ
DSGETLRVPLCV*PAEPAGVHP*GAARHAGRQAR
CRRVMALKGLGKPC*DLPRTAVLVGL*ILNCYS
IFYFPELIFYLQGWELSQLQL*SIVRSWERKAR
TCGVGGTRNS*ANFQEREKGLLRSLKALA*QRKR
LMCPIIFKNHP*KSVLSCGPISK*HCHIRTHET
DVRQLICFCF*VWEGKKEVGGMKHVLGGDALKI
*ELFTYHSSFEAKMDFSGEGPKPLLC*NLFY*IL
CQYFFS*KSS*ALRWSQYCNIM*VCFYLPAEDS
VTMKENCLYRPHWKSKTLSLRSGIPNSWDLYKK
DN*C*FGYRGIMCVNVIYN*KKLAHPFTYLLSVD
SRGLDLMLS*EALSL*TECILHPWFWTTVNVGA
LLKSWKGDRRRKIDLVLS*SYICSIDDLE*KLY
AWALPLRS*EISPECMSFQTNTL*FFFYVLFSKS
PPFFAPPHRQLCYSVERSVRLSDW*VKK*LETR
PKLKSLDLLSFRSDGN*ESISIKCDLAVFGREV
QGFPLKNLN*SGRMSGETVYAK*MAQVMPGPLAW
V*CLGTG*VKVNSRREE*LEGKGN*GRRFSEEN
KVVHEI*IDF*FPQGLNTNIVKQGSHLSAGCEG
ESENGVLEEKSTSN**GKVPNTIRISLTL*LPS*
KDKEEGWLLWTSMREGKKYFR*ASQGWPFLGFG
*EIGSTNYFLAYL*EN*LLFTPRSSCRPRIIRN
IAL*FMSVPILMNWSIHMESKGRIIPAVLF*SFG
CRCLNEALKIF*ELLRECWVELFGLHCFLLDYV
IFVGHWQKVCV*MCACV*MLCVCVCVCVCVCVC
VFADMQNCS*NNTLDF*VSLSTFQ*WVRVEPGPG
INYCLLFATRHKITFSNHPPFLLNLCRKLSFCE
YNSCSSYSR*DIRKCLLVLLRPLVC*NSLSL*V
HHFQDL*IVY*LRQLCRSGQMFFLLCPKARDHPR
KSGGWFIHWKCCVYAF*KHTLTSEEGWANLV*L
GETLIFPEMP*PLLVLALGFRVTFVPFSILERD
FPYIEP*FLWLWGLEVAFKDQMCFSSLWR*TLWV
LQH*PA*PSW*EIHHLSSSHAVHAAYSVGVYIN
LLNSYLHSKEVSRNHKYMYTYTYIKYIY*NKII
RNTASVIELFFLRILFF*AEKYRDEKDVILCLTI
FQLVFSYNLYFLKAENLEAR*KKGKAGAF*KSE
LR*LRDVAM*VSMFF*KKMQKNSYGGVFCLFIL
VADAGTSFCWRVFYIL*PDFILYFKLCEIKNKEF
HS*C

Frame 1

AAPRETP*RGGESAGGREGGRAAGRSRANEAAA
GGEEGAGEGRAGGAGAARARLGPERAHFAAKCQ
LPLECRARTVRARGKERQREFEIFGKKVGFPPSP
SPCY*SSLKRKTTVTANLLPSRTSPTPGTMKAA
VDLKPTLTIIKTEKVDLELFPSPDMECADVPLL
TPSSKEMMSQALKATFSGFTKEQQRLGIPKDPRQ
WTETHVRDWVMWAVNEFSLKGVDFQKFCMNGAA
LCALGKDCFLELAPDFVGDILWEHLEILQKEDV
KPYQVNGVNPAYPESRYTSDYFISYGIEHAQCVP
PSEFSEPSFITESYQTLHPISSEELLSLKYEND
YPSVILRDPLQTDTLQNDYFAIKQEVVTPDNMC
MGRTSRGKLGGQDSFESIESYDSCDRLTQSWSSQ
SSFNSLQRVPSYDSFDSEDYPAALPNHKPKGTF
KDYVRDRADLNKDKPVIPAAALAGYTGSGPIQL
WQFLLELLTDKSCQSFISWTGDGWEFKLSDPDEV
ARRWGKRKNKPKMNYEKLSRGLRYYYDKNIIHK
TAGKRYVYRFVCDLQSLLGYTPEELHAMLDVKP
DADE*WH*RGWGNPAETFQGQPCWLDSEF*IVIL
FFIFQNSFFTFRGGS*VSCSCNQLCAVGKGKPG
LVGWVGPEILEQIFRRGRRAFSEA*RLWLNRER
D*CVQSFLKIIHEKVS*VVDPLASDIVTSELMKL
M*GN*FASVFRSGRAKKRWVG*NMFWGGMH*KS
ENYLPITLVLKQRWTSVGRGQNRCCVKIYFIKF
CASIFFLKNRLKL*GGLSIAISCKFVFICRLRIL
SQ*KKTVYIDPIGKAKRSH*DQGSQIHGTYIRR
TINADLGTGELCV*MSSTIKKN*HIPLLTCYQW
ILGVWT*C*AKKH*VFELNVFCIPGFGRQ*T*EH
C*SPGREIEGGRLTWFFLSPISVA*MTWNKSCM
HGHYPSGPKK*VLNACRSKLTLCNFSFMSYFPR
VLHFLHPLTANSVIQ*REVYGFLIGE*KSNLRHD
LS*RV*TC*VLEVMEIKRAFQ*NVTWLSLEEKC
KAFL*RI*ISPVGCQVRLCMQNEWHR*CQGLLL
GSDVLAQGK*RLIPEERNDLKAKETKEGGSVRKI
RLSMRFE*IFSSPKV*IQT*SSKVVIFLLVVRG
NLKMEF*RKSQHLTSEEKCLIQLESPSLYSCPV
ERIRRRGGFYGLP*EKERNISGKLLRAGPFWDLD
EKLEVLTTF*HIFKKIDCYLLPDPLADPELSGT
*LCDS*VSPY**IGASIWKAKAELSQLYYFDLL
DAGALMKLSKYFRSCSGSVGWNCLDYIVFS*IM*
FLLGTGKRCVCECVHVCECCVCVCVCVCVCVCV
CLQTCKTAAEIIP*ISR*VFPHFNNG*E*NQGR
VSIIACCLQPGIKSLSQIIHRSY*IYAGNSPSVS
ITPAVPIADKI*ESAS*CSSARLFAKIPFLSKS
TIFKICR*CIS*DSFVDLARCFFSFVQRPETIP
GRVVGGLYTGNVAFMLFKNTR*LQRKDGQIWSSW
VKPLFSQRCLNLCWFWL*GSESLLFPSPFWRGT
SPT*SPDFCGCGDWR*HSKIRCAFPHFGDEHSG
FYSINLPNLHGEKYTISLLVMLCMPLTLLGSI*I
C*TLTYIPKKFQGTINICIHIHI*NIYIKIKLS
GILPQLLNFFF*EYFFFKLRSIGMKKMLYCV*L
FSNLYFHIIYIF*KLKI*KQDEKKEKQVLFKNQN
*GSLEM*RCKCRCFFKKKCKKILMAEFFVCLF*
*LMLAHHFAGEFFIYCSLISYCILNCVKLKTKN
FIHNA

Frame 2

RRREKRPKEEGRAREGEREGERPGDRERTRQPP
AERRERARAGQEERARRGRGWDPSALTSPQSAN
FPWSAGRAPSGRGGKKGSGNLRFLGRKSDFPRP
LPPVTNPH*KEKQQ*LQTCYHPVRPPLLAP*RRP
SISSRLSPSSRRKKSIWSFSPPRIWNVQMSHY*
LQAAKK*CLKH*KLLSVVSLKNSNDWGSQKTPG
SGQKPMFGTG*CGL*MNSA*KV*TSRSSV*MEQP
SAPWVKTAFSSWPQTLLGTSYGNI*RSCRKRM*
NHIKLMESTQPIQNPAIPRITSLAMVLSMPSVF
HHRSSQSPASSQSPIRRSIPSARKSSSPSSMRMT
TPRSFSETLSRQTPCRMTTLLSNKKSSPQTTCA
WGGPVVVNSGARTLLKA*RATIVVIASPSPGAA
SHLSTACSVFPPMTASTQRTIRLPCPTTSPRAPS
RTMCGTVLTSIRTSLSFLLLP*LATQAVDQSSY
GSFFWNYSLINPVSLLSAGQEMAGNSNFLTQMR
WPGDGERGKTNLR*IMRN*AVAYATITTKTSSTR
QRGNATCTALCVTCRACWGTPLRSCTPCWTSSQ
MPTSDGTEGAGETLLRPSKDSRVGWTLNFELLF
YFLFSRTHFLPSGVGAKSVAAVINCAQLGKESQD
LWGGWDQKFLSKFSGEGEGPSQKLEGSGLTEKE
TNVSNHF*KSSMKKCLELWTH*QVTLSHQNS*N
*CKAINLLLFLGLGGQKRGGWDETCFGGGCTENL
RTIYLSL*F*SKDGLQWGGAKTVVVLKFILLNF
VPVFFFLKIVLSSKVVSVLQYHVSLFLFAG*GF
CHNERKLFI*TPLEKQNALTEIRDPKFMGLI*EG
QLMLIWVQGNYVCECHLQLKKISTSLYLLVISG
FSGFGLNVELRSIKSLN*MYFASLVLDDSKRRS
TVEVLEGRSKEED*LGSFLVLYL*HR*LGIKAVC
MGITPQVLRNKS*MHVVPN*HSVIFLLCLIFQE
SSIFCTPSPPTLLFSREKCTAF*LVSEKVT*DT
T*VEEFRLAEF*K*WKLREHFNKM*LGCLWKRSA
RLSFEEFKLVR*DVR*DCVCKMNGTGDARASCL
GLMSWHRVSEG*FQKRGMT*RQRKLRKEVQ*GK
*GCP*DLNRFLVPPRFKYKHSQAR*SSFCWL*GG
I*KWSFRGKVNI*LVRKSA*YN*NLPHSIVAQL
KG*GGGVAFMDFHERRKEIFQVSFSGLALFGIW
MRNWKY*LLSSISLRKLIVIYSQILLQTQNYQEH
SSVIHECPHTDELEHPYGKQRQNYPSCIILIFW
MQVP**SSQNILGAAQGVLGGTVWTTLFSLRLC
DFCWALAKGVCVNVCMCVNVVCVCVCVCVCVCVC
VCRHAKLQLK*YLRFLGKSFHISIMGKSRTRAG
YQLLLAVCNQA*NHFLKSSTVPIKFMPETLLL*
V*LLQFL*QIRYKKVPPSAPPPACLLKFPFSLSP
PFSRFVDSVLVKTALSIWPDVFSPLSKGQRPSQ
EEWWVVYTLEMLRLCFLKTHVNFRGRMGKSGLA
G*NPYFPRDALTFVGFGFRVQSHFCSLLHSGEGL
PLHRALIFVAVGIGGSIQRSDVLFLTLEMNTLG
FTALTCLTFMVRNTPSLF*SCCACRLLCWGLYK
FVELLPTFQRSFKEP*IYVYIYIYKIYILK*NYQ
EYCLSY*TFFFKNTFFLS*EV*G*KRCYIVFDY
FPTCIFI*FIFFKS*KFRSKMKKRKSRCFLKIR
TEVA*RCSDVSVDVFLKKNAKKFLWRSFLFVYFS
S*CWHIILLESFLYTVA*FHIVF*TV*N*KQRI
SFIM

Sequence ETS1.aAug05

AGTTGGAAAGAGACCACAGACTTTGAGGGAAGCTCACTCAGGATCTGCTCTCCGGCAAAGTAGTAAGTGAGGTGCTGAGAGCAGAATGAGCTACTTTGTG
GATTCTGCTGGGAGCAGCCCCGTCCCTTACTCAGCGCCTCGTCCTGCAGTGGTGAGGCAAGGACCTAGCAACACTTATGAAGATCCTCGAATGAACTGTG
GTTTCCAGTCCAATTATCACCAGCAAAGACCTTGCTACCCCTTTTGGGATGAGATGGCAACTCAGGAAGTTCCTACTGGTCTTGAACACTGTGTCTCAGA
TATGGAATGTGCAGATGTCCCACTATTAACTCCAAGCAGCAAAGAAATGATGTCTCAAGCATTAAAAGCTACTTTCAGTGGTTTCACTAAAGAACAGCAA
CGACTGGGGATCCCAAAAGACCCCCGGCAGTGGACAGAAACCCATGTTCGGGACTGGGTGATGTGGGCTGTGAATGAATTCAGCCTGAAAGGTGTAGACT
TCCAGAAGTTCTGTATGAATGGAGCAGCCCTCTGCGCCCTGGGTAAAGACTGCTTTCTCGAGCTGGCCCCAGACTTTGTTGGGGACATCTTATGGGAACA
TCTAGAGATCCTGCAGAAAGAGGATGTGAAACCATATCAAGTTAATGGAGTCAACCCAGCCTATCCAGAATCCCGCTATACCTCGGATTACTTCATTAGC
TATGGTATTGAGCATGCCCAGTGTGTTCCACCATCGGAGTTCTCAGAGCCCAGCTTCATCACAGAGTCCTATCAGACGCTCCATCCCATCAGCTCGGAAG
AGCTCCTCTCCCTCAAGTATGAGAATGACTACCCCTCGGTCATTCTCCGAGACCCTCTCCAGACAGACACCTTGCAGAATGACTACTTTGCTATCAAACA
AGAAGTCGTCACCCCAGACAACATGTGCATGGGGAGGACCAGTCGTGGTAAACTCGGGGGCCAGGACTCTTTTGAAAGCATAGAGAGCTACGATAGTTGT
GATCGCCTCACCCAGTCCTGGAGCAGCCAGTCATCTTTCAACAGCCTGCAGCGTGTTCCCTCCTATGACAGCTTCGACTCAGAGGACTATCCGGCTGCCC
TGCCCAACCACAAGCCCAAGGGCACCTTCAAGGACTATGTGCGGGACCGTGCTGACCTCAATAAGGACAAGCCTGTCATTCCTGCTGCTGCCCTAGCTGG
CTACACAGGCAGTGGACCAATCCAGCTATGGCAGTTTCTTCTGGAATTACTCACTGATAAATCCTGTCAGTCTTTTATCAGCTGGACAGGAGATGGCTGG
GAATTCAAACTTTCTGACCCAGATGAGGTGGCCAGGAGATGGGGAAAGAGGAAAAACAAACCTAAGATGAATTATGAGAAACTGAGCCGTGGCCTACGCT
ACTATTACGACAAAAACATCATCCACAAGACAGCGGGGAAACGCTACGTGTACCGCTTTGTGTGTGACCTGCAGAGCCTGCTGGGGTACACCCCTGAGGA
GCTGCACGCCATGCTGGACGTCAAGCCAGATGCCGACGAGTGATGGCACTGAAGGGGCTGGGGAAACCCTGCTGAGACCTTCCAAGGACAGCCGTGTTGG
TTGGACTCTGAATTTTGAATTGTTATTCTATTTTTTATTTTCCAGAACTCATTTTTTACCTTCAGGGGTGGGAGCTAAGTCAGTTGCAGCTGTAATCAAT
TGTGCGCAGTTGGGAAAGGAAAGCCAGGACTTGTGGGGTGGGTGGGACCAGAAATTCTTGAGCAAATTTTCAGGAGAGGGAGAAGGGCCTTCTCAGAAGC
TTGAAGGCTCTGGCTTAACAGAGAAAGAGACTAATGTGTCCAATCATTTTTAAAAATCATCCATGAAAAAGTGTCTTGAGTTGTGGACCCATTAGCAAGT
GACATTGTCACATCAGAACTCATGAAACTGATGTAAGGCAATTAATTTGCTTCTGTTTTTAGGTCTGGGAGGGCAAAAAAGAGGTGGGTGGGATGAAACA
TGTTTTGGGGGGGGATGCACTGAAAATCTGAGAACTATTTACCTATCACTCTAGTTTTGAAGCAAAGATGGACTTCAGTGGGGAGGGGCCAAAACCGTTG
TTGTGTTAAAATTTATTTTATTAAATTTTGTGCCAGTATTTTTTTTCTTAAAAATCGTCTTAAGCTCTAAGGTGGTCTCAGTATTGCAATATCATGTAAG
TTTGTTTTTATTTGCCGGCTGAGGATTCTGTCACAATGAAAGAAAACTGTTTATATAGACCCCATTGGAAAAGCAAAACGCTCTCACTGAGATCAGGGAT
CCCAAATTCATGGGACTTATATAAGAAGGACAATTAATGCTGATTTGGGTACAGGGGAATTATGTGTGTGAATGTCATCTACAATTAAAAAAAATTAGCA
CATCCCTTTACTTACTTGTTATCAGTGGATTCTCGGGGTTTGGACTTAATGTTGAGCTAAGAAGCATTAAGTCTTTGAACTGAATGTATTTTGCATCCCT
GGTTTTGGACGACAGTAAACGTAGGAGCACTGTTGAAGTCCTGGAAGGGAGATCGAAGGAGGAAGATTGACTTGGTTCTTTCTTAGTCCTATATCTGTAG
CATAGATGACTTGGAATAAAAGCTGTATGCATGGGCATTACCCCTCAGGTCCTAAGAAATAAGTCCTGAATGCATGTCGTTCCAAACTAACACTCTGTAA
TTTTTCTTTTATGTCTTATTTTCCAAGAGTCCTCCATTTTTTGCACCCCCTCACCGCCAACTCTGTTATTCAGTAGAGAGAAGTGTACGGCTTTCTGATT
GGTGAGTGAAAAAGTAACTTGAGACACGACCTAAGTTGAAGAGTTTAGACTTGCTGAGTTTTAGAAGTGATGGAAATTAAGAGAGCATTTCAATAAAATG
TGACTTGGCTGTCTTTGGAAGAGAAGTGCAAGGCTTTCCTTTGAAGAATTTAAATTAGTCCGGTAGGATGTCAGGTGAGACTGTGTATGCAAAATGAATG
GCACAGGTGATGCCAGGGCCTCTTGCTTGGGTCTGATGTCTTGGCACAGGGTAAGTGAAGGTTAATTCCAGAAGAGAGGAATGACTTGAAGGCAAAGGAA
ACTAAGGAAGGAGGTTCAGTGAGGAAAATAAGGTTGTCCATGAGATTTGAATAGATTTTTAGTTCCCCCAAGGTTTAAATACAAACATAGTCAAGCAAGG
TAGTCATCTTTCTGCTGGTTGTGAGGGGGAATCTGAAAATGGAGTTTTAGAGGAAAAGTCAACATCTAACTAGTGAGGAAAAGTGCCTAATACAATTAGA
ATCTCCCTCACTCTATAGTTGCCCAGTTGAAAGGATAAGGAGGAGGGGTGGCTTTTATGGACTTCCATGAGAGAAGGAAAGAAATATTTCAGGTAAGCTT
CTCAGGGCTGGCCCTTTTTGGGATTTGGATGAGAAATTGGAAGTACTAACTACTTTCTAGCATATCTTTAAGAAAATTGATTGTTATTTACTCCCAGATC
CTCTTGCAGACCCAGAATTATCAGGAACATAGCTCTGTGATTCATGAGTGTCCCCATACTGATGAATTGGAGCATCCATATGGAAAGCAAAGGCAGAATT
ATCCCAGCTGTATTATTTTGATCTTTTGGATGCAGGTGCCTTAATGAAGCTCTCAAAATATTTTAGGAGCTGCTCAGGGAGTGTTGGGTGGAACTGTTTG
GACTACATTGTTTTCTCTTAGATTATGTGATTTTTGTTGGGCACTGGCAAAAGGTGTGTGTGTGAATGTGTGCATGTGTGTGAATGTTGTGTGTGTGTGT
GTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTTTGCAGACATGCAAAACTGCAGCTGAAATAATACCTTAGATTTCTAGGTAAGTCTTTCCACATTTCAA
TAATGGGTAAGAGTAGAACCAGGGCCGGGTATCAATTATTGCTTGCTGTTTGCAACCAGGCATAAAATCACTTTCTCAAATCATCCACCGTTCCTATTAA
ATTTATGCCGGAAACTCTCCTTCTGTGAGTATAACTCCTGCAGTTCCTATAGCAGATAAGATATAAGAAAGTGCCTCCTAGTGCTCCTCCGCCCGCTTGT
TTGCTAAAATTCCCTTTCTCTCTAAGTCCACCATTTTCAAGATTTGTAGATAGTGTATTAGTTAAGACAGCTTTGTCGATCTGGCCAGATGTTTTTTCTC
CTTTGTCCAAAGGCCAGAGACCATCCCAGGAAGAGTGGTGGGTGGTTTATACACTGGAAATGTTGCGTTTATGCTTTTTAAAAACACACGTTAACTTCAG
AGGAAGGATGGGCAAATCTGGTCTAGCTGGGTGAAACCCTTATTTTCCCAGAGATGCCTTAACCTTTGTTGGTTTTGGCTTTAGGGTTCAGAGTCACTTT
TGTTCCCTTCTCCATTCTGGAGAGGGACTTCCCCTACATAGAGCCCTGATTTTTGTGGCTGTGGGGATTGGAGGTAGCATTCAAAGATCAGATGTGCTTT
TCCTCACTTTGGAGATGAACACTCTGGGTTTTACAGCATTAACCTGCCTAACCTTCATGGTGAGAAATACACCATCTCTCTTCTAGTCATGCTGTGCATG
CCGCTTACTCTGTTGGGGTCTATATAAATTTGTTGAACTCTTACCTACATTCCAAAGAAGTTTCAAGGAACCATAAATATATGTATACATATACATATAT
AAAATATATATATTAAAATAAAATTATCAGGAATACTGCCTCAGTTATTGAACTTTTTTTTTTAAGAATACTTTTTTTTTAAGCTGAGAAGTATAGGGAT
GAAAAAGATGTTATATTGTGTTTGACTATTTTCCAACTTGTATTTTCATATAATTTATATTTTTTAAAAGCTGAAAATTTAGAAGCAAGATGAAAAAAAG
GAAAAGCAGGTGCTTTTTAAAAATCAGAACTGAGGTAGCTTAGAGATGTAGCGATGTAAGTGTCGATGTTTTTTTAAAAAAAAATGCAAAAAAATTCTTA
TGGCGGAGTTTTTTGTTTGTTTATTTTAGTAGCTGATGCTGGCACATCATTTTGCTGGAGAGTTTTTTATATACTGTAGCCTGATTTCATATTGTATTTT
AAACTGTGTGAAATTAAAAACAAAGAATTTCATTCATAATGCT
  • ETS1.u.f.12 (forward primer)
  • ETS1.u.r.14 (reverse primer)
  • Single exon skipping

Frame 0

SWKETTDFEGSSLRICSPAK**VRC*EQNELLC
GFCWEQPRPLLSASSCSGEART*QHL*RSSNELW
FPVQLSPAKTLLPLLG*DGNSGSSYWS*TLCLR
YGMCRCPTINSKQQRNDVSSIKSYFQWFH*RTA
TTGDPKRPPAVDRNPCSGLGDVGCE*IQPERCRL
PEVLYEWSSPLRPG*RLLSRAGPRLCWGHLMGT
SRDPAERGCETISS*WSQPSLSRIPLYLGLLH*
LWY*ACPVCSTIGVLRAQLHHRVLSDAPSHQLGR
APLPQV*E*LPLGHSPRPSPDRHLAE*LLCYQT
RSRHPRQHVHGEDQSW*TRGPGLF*KHRELR*L
*SPHPVLEQPVIFQQPAACSLL*QLRLRGLSGCP
AQPQAQGHLQGLCAGPC*PQ*GQACHSCCCPSW
LHRQWTNPAMAVSSGITH**ILSVFYQLDRRWL
GIQTF*PR*GGQEMGKEEKQT*DEL*ETEPWPTL
LLRQKHHPQDSGETLRVPLCV*PAEPAGVHP*G
AARHAGRQARCRRVMALKGLGKPC*DLPRTAVL
VGL*ILNCYSIFYFPELIFYLQGWELSQLQL*SI
VRSWERKARTCGVGGTRNS*ANFQEREKGLLRS
LKALA*QRKRLMCPIIFKNHP*KSVLSCGPISK
*HCHIRTHETDVRQLICFCF*VWEGKKEVGGMKH
VLGGDALKI*ELFTYHSSFEAKMDFSGEGPKPL
LC*NLFY*ILCQYFFS*KSS*ALRWSQYCNIM*
VCFYLPAEDSVTMKENCLYRPHWKSKTLSLRSGI
PNSWDLYKKDN*C*FGYRGIMCVNVIYN*KKLA
HPFTYLLSVDSRGLDLMLS*EALSL*TECILHP
WFWTTVNVGALLKSWKGDRRRKIDLVLS*SYICS
IDDLE*KLYAWALPLRS*EISPECMSFQTNTL*
FFFYVLFSKSPPFFAPPHRQLCYSVERSVRLSD
W*VKK*LETRPKLKSLDLLSFRSDGN*ESISIKC
DLAVFGREVQGFPLKNLN*SGRMSGETVYAK*M
AQVMPGPLAWV*CLGTG*VKVNSRREE*LEGKG
N*GRRFSEENKVVHEI*IDF*FPQGLNTNIVKQG
SHLSAGCEGESENGVLEEKSTSN**GKVPNTIR
ISLTL*LPS*KDKEEGWLLWTSMREGKKYFR*A
SQGWPFLGFG*EIGSTNYFLAYL*EN*LLFTPRS
SCRPRIIRNIAL*FMSVPILMNWSIHMESKGRI
IPAVLF*SFGCRCLNEALKIF*ELLRECWVELF
GLHCFLLDYVIFVGHWQKVCV*MCACV*MLCVCV
CVCVCVCVCVFADMQNCS*NNTLDF*VSLSTFQ
*WVRVEPGPGINYCLLFATRHKITFSNHPPFLL
NLCRKLSFCEYNSCSSYSR*DIRKCLLVLLRPLV
C*NSLSL*VHHFQDL*IVY*LRQLCRSGQMFFL
LCPKARDHPRKSGGWFIHWKCCVYAF*KHTLTS
EEGWANLV*LGETLIFPEMP*PLLVLALGFRVTF
VPFSILERDFPYIEP*FLWLWGLEVAFKDQMCF
SSLWR*TLWVLQH*PA*PSW*EIHHLSSSHAVH
AAYSVGVYINLLNSYLHSKEVSRNHKYMYTYTYI
KYIY*NKIIRNTASVIELFFLRILFF*AEKYRD
EKDVILCLTIFQLVFSYNLYFLKAENLEAR*KK
GKAGAF*KSELR*LRDVAM*VSMFF*KKMQKNSY
GGVFCLFILVADAGTSFCWRVFYIL*PDFILYF
KLCEIKNKEFHS*C

Frame 1

VGKRPQTLREAHSGSALRQSSK*GAESRMSYFV
DSAGSSPVPYSAPRPAVVRQGPSNTYEDPRMNC
GFQSNYHQQRPCYPFWDEMATQEVPTGLEHCVSD
MECADVPLLTPSSKEMMSQALKATFSGFTKEQQ
RLGIPKDPRQWTETHVRDWVMWAVNEFSLKGVD
FQKFCMNGAALCALGKDCFLELAPDFVGDILWEH
LEILQKEDVKPYQVNGVNPAYPESRYTSDYFIS
YGIEHAQCVPPSEFSEPSFITESYQTLHPISSE
ELLSLKYENDYPSVILRDPLQTDTLQNDYFAIKQ
EVVTPDNMCMGRTSRGKLGGQDSFESIESYDSC
DRLTQSWSSQSSFNSLQRVPSYDSFDSEDYPAA
LPNHKPKGTFKDYVRDRADLNKDKPVIPAAALAG
YTGSGPIQLWQFLLELLTDKSCQSFISWTGDGW
EFKLSDPDEVARRWGKRKNKPKMNYEKLSRGLR
YYYDKNIIHKTAGKRYVYRFVCDLQSLLGYTPEE
LHAMLDVKPDADE*WH*RGWGNPAETFQGQPCW
LDSEF*IVILFFIFQNSFFTFRGGS*VSCSCNQ
LCAVGKGKPGLVGWVGPEILEQIFRRGRRAFSEA
*RLWLNRERD*CVQSFLKIIHEKVS*VVDPLAS
DIVTSELMKLM*GN*FASVFRSGRAKKRWVG*N
MFWGGMH*KSENYLPITLVLKQRWTSVGRGQNRC
CVKIYFIKFCASIFFLKNRLKL*GGLSIAISCK
FVFICRLRILSQ*KKTVYIDPIGKAKRSH*DQG
SQIHGTYIRRTINADLGTGELCV*MSSTIKKN*H
IPLLTCYQWILGVWT*C*AKKH*VFELNVFCIP
GFGRQ*T*EHC*SPGREIEGGRLTWFFLSPISV
A*MTWNKSCMHGHYPSGPKK*VLNACRSKLTLCN
FSFMSYFPRVLHFLHPLTANSVIQ*REVYGFLI
GE*KSNLRHDLS*RV*TC*VLEVMEIKRAFQ*N
VTWLSLEEKCKAFL*RI*ISPVGCQVRLCMQNEW
HR*CQGLLLGSDVLAQGK*RLIPEERNDLKAKE
TKEGGSVRKIRLSMRFE*IFSSPKV*IQT*SSK
VVIFLLVVRGNLKMEF*RKSQHLTSEEKCLIQLE
SPSLYSCPVERIRRRGGFYGLP*EKERNISGKL
LRAGPFWDLDEKLEVLTTF*HIFKKIDCYLLPD
PLADPELSGT*LCDS*VSPY**IGASIWKAKAEL
SQLYYFDLLDAGALMKLSKYFRSCSGSVGWNCL
DYIVFS*IM*FLLGTGKRCVCECVHVCECCVCV
CVCVCVCVCVCLQTCKTAAEIIP*ISR*VFPHFN
NG*E*NQGRVSIIACCLQPGIKSLSQIIHRSY*
IYAGNSPSVSITPAVPIADKI*ESAS*CSSARL
FAKIPFLSKSTIFKICR*CIS*DSFVDLARCFFS
FVQRPETIPGRVVGGLYTGNVAFMLFKNTR*LQ
RKDGQIWSSWVKPLFSQRCLNLCWFWL*GSESL
LFPSPFWRGTSPT*SPDFCGCGDWR*HSKIRCAF
PHFGDEHSGFYSINLPNLHGEKYTISLLVMLCM
PLTLLGSI*IC*TLTYIPKKFQGTINICIHIHI
*NIYIKIKLSGILPQLLNFFF*EYFFFKLRSIGM
KKMLYCV*LFSNLYFHIIYIF*KLKI*KQDEKK
EKQVLFKNQN*GSLEM*RCKCRCFFKKKCKKIL
MAEFFVCLF**LMLAHHFAGEFFIYCSLISYCIL
NCVKLKTKNFIHNA

Frame 2

LERDHRL*GKLTQDLLSGKVVSEVLRAE*ATLW
ILLGAAPSLTQRLVLQW*GKDLATLMKILE*TV
VSSPIITSKDLATPFGMRWQLRKFLLVLNTVSQ
IWNVQMSHY*LQAAKK*CLKH*KLLSVVSLKNSN
DWGSQKTPGSGQKPMFGTG*CGL*MNSA*KV*T
SRSSV*MEQPSAPWVKTAFSSWPQTLLGTSYGN
I*RSCRKRM*NHIKLMESTQPIQNPAIPRITSLA
MVLSMPSVFHHRSSQSPASSQSPIRRSIPSARK
SSSPSSMRMTTPRSFSETLSRQTPCRMTTLLSN
KKSSPQTTCAWGGPVVVNSGARTLLKA*RATIVV
IASPSPGAASHLSTACSVFPPMTASTQRTIRLP
CPTTSPRAPSRTMCGTVLTSIRTSLSFLLLP*L
ATQAVDQSSYGSFFWNYSLINPVSLLSAGQEMAG
NSNFLTQMRWPGDGERGKTNLR*IMRN*AVAYA
TITTKTSSTRQRGNATCTALCVTCRACWGTPLR
SCTPCWTSSQMPTSDGTEGAGETLLRPSKDSRVG
WTLNFELLFYFLFSRTHFLPSGVGAKSVAAVIN
CAQLGKESQDLWGGWDQKFLSKFSGEGEGPSQK
LEGSGLTEKETNVSNHF*KSSMKKCLELWTH*QV
TLSHQNS*N*CKAINLLLFLGLGGQKRGGWDET
CFGGGCTENLRTIYLSL*F*SKDGLQWGGAKTV
VVLKFILLNFVPVFFFLKIVLSSKVVSVLQYHVS
LFLFAG*GFCHNERKLFI*TPLEKQNALTEIRD
PKFMGLI*EGQLMLIWVQGNYVCECHLQLKKIS
TSLYLLVISGFSGFGLNVELRSIKSLN*MYFASL
VLDDSKRRSTVEVLEGRSKEED*LGSFLVLYL*
HR*LGIKAVCMGITPQVLRNKS*MHVVPN*HSV
IFLLCLIFQESSIFCTPSPPTLLFSREKCTAF*L
VSEKVT*DTT*VEEFRLAEF*K*WKLREHFNKM
*LGCLWKRSARLSFEEFKLVR*DVR*DCVCKMN
GTGDARASCLGLMSWHRVSEG*FQKRGMT*RQRK
LRKEVQ*GK*GCP*DLNRFLVPPRFKYKHSQAR
*SSFCWL*GGI*KWSFRGKVNI*LVRKSA*YN*
NLPHSIVAQLKG*GGGVAFMDFHERRKEIFQVSF
SGLALFGIWMRNWKY*LLSSISLRKLIVIYSQI
LLQTQNYQEHSSVIHECPHTDELEHPYGKQRQN
YPSCIILIFWMQVP**SSQNILGAAQGVLGGTVW
TTLFSLRLCDFCWALAKGVCVNVCMCVNVVCVC
VCVCVCVCVCVCRHAKLQLK*YLRFLGKSFHIS
IMGKSRTRAGYQLLLAVCNQA*NHFLKSSTVPIK
FMPETLLL*V*LLQFL*QIRYKKVPPSAPPPAC
LLKFPFSLSPPFSRFVDSVLVKTALSIWPDVFS
PLSKGQRPSQEEWWVVYTLEMLRLCFLKTHVNFR
GRMGKSGLAG*NPYFPRDALTFVGFGFRVQSHF
CSLLHSGEGLPLHRALIFVAVGIGGSIQRSDVL
FLTLEMNTLGFTALTCLTFMVRNTPSLF*SCCAC
RLLCWGLYKFVELLPTFQRSFKEP*IYVYIYIY
KIYILK*NYQEYCLSY*TFFFKNTFFLS*EV*G
*KRCYIVFDYFPTCIFI*FIFFKS*KFRSKMKKR
KSRCFLKIRTEVA*RCSDVSVDVFLKKNAKKFL
WRSFLFVYFSS*CWHIILLESFLYTVA*FHIVF
*TV*N*KQRISFIM

Copyright ©2008,2017, all rights reserved.