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Sequences

Sequence POLI.cAug05

GACGACGAGGAAGACGCCGAGGCCTGGGCCATGGAACTGGCGGACGTGGGGGCGGCAGCCAGCTCGCAGGGTGCGCCGCAGCCAGAGGAGCCAGCGGCCT
CCTTGGGTGTAAATGAGAAGGGTGGGGCAGGCGGACGCTCGGGGCGGCGGCCACTGGGGCGCGACCGTCCCCGCCCCACTCGGCTCCTCTAAGAGAGGGC
TGCCTCCCTCTGCCTTGTGTTACGCGGCGGGTACCTCTAGAGGAATGGCTTCACCCAGCAGGAGTAGGGTGGGGCGCGTCCACACTACAAATACGTGTCG
AGGGTTTATCTGCGCCGTCCTTTCCTCTGTGAGGGGCGAGGTGGGGCGGGAATCCCTCAGCCAGCCCGACGAAAACTGCAGAGGCTTCTGGGCCTTTTAA
CTTTGGAGAAGTTGAGGACCTTGTCGCTCATTTGGCAGAAGGTGGGACCCGGATCTCAGTCCTGGCAGGAAGGGATGGCTCAGAACCTAGGCGGAGTCAG
GTCCGCTGTGGTCACGTCTCCGGTGACCCACTTCCAGCTCTGGTCTTTACCTTGTACCGCCCACCTCAGGGCCTGGATGTAAAGGCACCGGTTCTCATTT
CCTGCTGGTTTTGTTTCATTCATTAATTTAGAGACAAGGTCTCCCTGCAGCCTCGAACCCCTGGGCTCAAGTGATCCTCCGCCCCAGCCTCTCCGTCCCG
AGTAGCTGGGACAGCAGGCACGTGCCACCACACCTGGCTGATTTTCAGATTTTTTTAGATCAGGTGTAGCTGTGTTGTCCAGGCTGGTCTCAAACTCCAG
CCACAAGCGATCCTTCCACCTCAGCTTCGAAAAGTATTGGGATTACAGTAGTTAGCCATCGTGCCTGGCCTTTTAAATTTTGGAACTTTAGGTTTACCTG
AAAGTTGCAGAGCTAGATCCCCCTAGTGTTAACATAAACTCAGTACATTTGTCAAAACTAGGAAATTAACATTGGTATAATACTATTAATTGAACTACAC
GCTTTATTAATATTCTACCAGTTTTTCTGCTAACGTTCATTTTCTGTTCCAGGATCCCAACCAGAATATTGTATTGTATTTTGCCTGTCTTGTTTTTAGC
CAGTGTTGAGAGAAGGAGTCGCCTCTGTCATTCCCTCCCCGACAAATAATGACCTAACAACTTTTTAAAATCAAAGAACTATTCAGTCTTTCAATTTAGT
GAATATTTATTGGTGGTCTGTTATGTCCTAGACACTGTTTTAGGCACTGGCGATTTAGCATTAAACCAGATAATCCTGCTGCCATGGGAGCTAAAAATAG
CCCACACTTGTACCCACTGGTTGTCTTTTGCCATTTTGTATTTCAGTTTTTGTTGGTTTGTTTGTTTTAAATGTAAGGGCATGCTGCTTAGAATAATTTT
CAAGCTGTGTGAAAATCAACGTCATTTCAACTTTTCTGCCCCTTCTGGTTTACACTAAGAGCTACTATAAACTTCCAGGTGATAGTATTAGCTCTTTCAT
CATCCATTATTTATCACATTTTTTCCCTTCAAACTTATTACTATCCTGAGAAAAACGCAGTGCACAAACAGTAATTAAGAGGACTGAAGACCCTACCCTA
AGTGGAGTTTCATGTCTTTGTAATTTTTCGATGCTTTCACACATAATCCAGGAGAAAACACGTCACTCTGCATTCTTCCTTCACAGGTACCATGTTTTAA
GGAACTGTCAGTTGCTCAGAGATAATAAGCAGCCTGAATTTCTTTTTATTTCTTTGCATATTGTGCAGGAGTTCATGATCAAGTGTTGCCCACACCAAAT
GCTTCATCCAGAGTCATAGTACATGTGGATCTGGATTGCTTTTATGCACAAGTAGAAATGATCTCAAATCCAGAGCTAAAAGACAAACCTTTAGGGGTTC
AACAGAAATATTTGGTGGTTACCTGCAACTATGAAGCTAGGAAACTTGGAGTTAAGAAACTTATGAATGTCAGAGATGCAAAAGAAAAGTGTCCACAGTT
GGTATTAGTTAATGGAGAAGACCTGACCCGCTACAGAGAAATGTCTTATAAGGTTACAGAATTACTGGAAGAATTTAGTCCAGTTGTTGAGAGACTTGGA
TTTGATGAAAATTTTGTGGATCTAACAGAAATGGTTGAGAAGAGACTACAGCAGCTGCAAAGTGATGAACTTTCTGCGGTGACTGTGTCGGGTCATGTAT
ACAATAATCAGTCTATAAACCTGCTTGACGTCTTGCACATCAGACTACTTGTTGGATCTCAGATTGCAGCAGAGATGCGGGAAGCCATGTATAATCAGTT
GGGGCTCACTGGCTGTGCTGGAGTGGCTTCTAATAAACTGTTGGCAAAATTAGTTTCTGGTGTCTTTAAACCAAATCAACAAACAGTCTTATTACCTGAA
AGTTGTCAACATCTTATTCATAGTTTGAATCACATAAAGGAAATACCTGGTATTGGCTATAAAACTGCCAAATGTCTTGAAGCACTGGGTATCAATAGTG
TGCGTGATCTCCAAACCTTTTCACCCAAAATTTTAGAAAAAGAATTAGGAATTTCAGTTGCTCAGCGTATCCAAAAGCTCAGTTTTGGAGAGGATAACTC
CCCTGTGATACTCTCAGGACCACCTCAGTGAGTACAATAGCTTGCAGATAAAAAACTGTTAATATAAAAGTGAACTAAATGGCTCAAACTAAGGACAAGA
G
TCCTTTAGTGAAGAAGATTCATTTAAAAAATGTTCATCTGAAGTTGAAGCTAAAAATAAGATTGAAGAACTACTTGCTAGTCTTTTAAACAGAGTATGC
CAAGATGGAAGGAAGCCTCATACAGTGAGATTAATAATCCGTCGGTATTCCTCTGAGAAGCACTATGGTCGTGAGAGTCGTCAGTGCCCTATTCCTTCAC
ATGTAATTCAGAAATTAGGGACAGGAAATTATGATGTGATGACCCCAATGGTTGATATACTTATGAAACTTTTTCGAAATATGGTGAATGTGAAGATGCC
ATTTCACCTTACCCTTCTAAGTGTGTGCTTCTGCAACCTTAAAGCACTAAATACTGCTAAGAAAGGGCTTATTGATTATTATTTAATGCCATCATTATCA
ACTACTTCACGCTCTGGCAAGCACAGTTTTAAAATGAAAGACACTCATATGGAAGATTTTCCCAAAGACAAAGAAACAAACCGGGATTTCCTACCAAGTG
GAAGAATTGAAAGTACAAGAACTAGGGAGTCTCCACTAGATACCACAAATTTTTCTAAAGAAAAAGACATTAATGAATTCCCACTCTGTTCACTTCCTGA
AGGTGTTGACCAAGAAGTCTTCAAGCAGCTTCCAGTAGATATTCAAGAAGAAATCCTTTCTGGAAAATCTAGGGAAAAATTTCAAGGGAAAGGAAGTGTG
AGTTGTCCATTACATGCCTCTAGAGGAGTATTATCTTTCTTTTCTAAAAAACAAATGCAAGATATTCCCATAAATCCTAGAGATCATTTATCCAGTAGCA
AACAGGTATCCTCTGTATCTCCTTGTGAACCGGGAACATCAGGCTTTAATAGCAGTAGTTCTTCTTACATGTCTAGCCAAAAGGATTATTCATATTATTT
AGATAATAGATTAAAAGATGAACGAATAAGTCAAGGACCTAAAGAACCTCAAGGATTCCACTTTACAAATTCAAACCCTGCTGTGTCTGCTTTTCATTCA
TTTCCAAACTTGCAGAGTGAGCAACTTTTCTCCAGAAACCACACTACAGATAGCCATAAGCAAACAGTAGCAACAGACTCTCATGAAGGACTTACAGAAA
ATAGAGAGCCAGATTCTGTTGATGAGAAAATTACTTTCCCTTCTGACATTGATCCTCAAGTTTTCTATGAACTACCAGAAGCAGTACAAAAGGAACTGCT
GGCAGAGTGGAAGAGAGCAGGATCAGATTTCCACATTGGACATAAATAAGCATATTCAGCAAAAAGGTCTGAAAAGCAAGGGAATACCATTATTTTCGGA
TTAGCGGTTTATTAAGCTCTTCTATATTAAACACTAATAGATATTCAATAACGGAGTAAACTGTTCCAGATAAAGCAAGAATAGTTGCAAGAAGTAAATT
CTGGCACAAAGCGTAAAAATATAACAGAAGAAATAATGTAAAATACTATCTTTTATGTCTAAAGCCATTTTATATTACTTTTCAATAAAAAGAATATCAT
GGTCAACAT
  • POLI.F8 (forward primer)
  • POLI.R14 (reverse primer)
  • Intron retention

Frame 0

DDEEDAEAWAMELADVGAAASSQGAPQPEEPAA
SLGVNEKGGAGGRSGRRPLGRDRPRPTRLL*ERA
ASLCLVLRGGYL*RNGFTQQE*GGARPHYKYVS
RVYLRRPFLCEGRGGAGIPQPARRKLQRLLGLL
TLEKLRTLSLIWQKVGPGSQSWQEGMAQNLGGVR
SAVVTSPVTHFQLWSLPCTAHLRAWM*RHRFSF
PAGFVSFINLETRSPCSLEPLGSSDPPPQPLRP
E*LGQQARATTPG*FSDFFRSGVAVLSRLVSNSS
HKRSFHLSFEKYWDYSS*PSCLAF*ILEL*VYL
KVAELDPPSVNINSVHLSKLGN*HWYNTIN*TT
RFINILPVFLLTFIFCSRIPTRILYCILPVLFLA
SVERRSRLCHSLPDK**PNNFLKSKNYSVFQFS
EYLLVVCYVLDTVLGTGDLALNQIILLPWELKI
AHTCTHWLSFAILYFSFCWFVCFKCKGMLLRIIF
KLCENQRHFNFSAPSGLH*ELL*TSR**Y*LFH
HPLFITFFPFKLITILRKTQCTNSN*ED*RPYP
KWSFMSL*FFDAFTHNPGENTSLCILPSQVPCFK
ELSVAQR**AA*ISFYFFAYCAGVHDQVLPTPN
ASSRVIVHVDLDCFYAQVEMISNPELKDKPLGV
QQKYLVVTCNYEARKLGVKKLMNVRDAKEKCPQL
VLVNGEDLTRYREMSYKVTELLEEFSPVVERLG
FDENFVDLTEMVEKRLQQLQSDELSAVTVSGHV
YNNQSINLLDVLHIRLLVGSQIAAEMREAMYNQL
GLTGCAGVASNKLLAKLVSGVFKPNQQTVLLPE
SCQHLIHSLNHIKEIPGIGYKTAKCLEALGINS
VRDLQTFSPKILEKELGISVAQRIQKLSFGEDNS
PVILSGPPQ*VQ*LADKKLLI*K*TKWLKLRTR
VL**RRFI*KMFI*S*S*K*D*RTTC*SFKQSM
PRWKEASYSEINNPSVFL*EALWS*ESSVPYSFT
CNSEIRDRKL*CDDPNG*YTYETFSKYGECEDA
ISPYPSKCVLLQP*STKYC*ERAY*LLFNAIII
NYFTLWQAQF*NERHSYGRFSQRQRNKPGFPTKW
KN*KYKN*GVSTRYHKFF*RKRH**IPTLFTS*
RC*PRSLQAASSRYSRRNPFWKI*GKISRERKC
ELSITCL*RSIIFLF*KTNARYSHKS*RSFIQ*Q
TGILCISL*TGNIRL**Q*FFLHV*PKGLFILF
R**IKR*TNKSRT*RTSRIPLYKFKPCCVCFSF
ISKLAE*ATFLQKPHYR*P*ANSSNRLS*RTYRK
*RARFC**ENYFPF*H*SSSFL*TTRSSTKGTA
GRVEESRIRFPHWT*ISIFSKKV*KAREYHYFR
ISGLLSSSILNTNRYSITE*TVPDKARIVARSKF
WHKA*KYNRRNNVKYYLLCLKPFYITFQ*KEYH
GQH

Frame 1

TTRKTPRPGPWNWRTWGRQPARRVRRSQRSQRP
PWV*MRRVGQADARGGGHWGATVPAPLGSSKRG
LPPSALCYAAGTSRGMASPSRSRVGRVHTTNTCR
GFICAVLSSVRGEVGRESLSQPDENCRGFWAF*
LWRS*GPCRSFGRRWDPDLSPGRKGWLRT*AES
GPLWSRLR*PTSSSGLYLVPPTSGPGCKGTGSHF
LLVLFHSLI*RQGLPAASNPWAQVILRPSLSVP
SSWDSRHVPPHLADFQIFLDQV*LCCPGWSQTP
ATSDPSTSASKSIGITVVSHRAWPFKFWNFRFT*
KLQS*IPLVLT*TQYICQN*EINIGIILLIELH
ALLIFYQFFC*RSFSVPGSQPEYCIVFCLSCF*
PVLREGVASVIPSPTNNDLTTF*NQRTIQSFNLV
NIYWWSVMS*TLF*ALAI*H*TR*SCCHGS*K*
PTLVPTGCLLPFCISVFVGLFVLNVRACCLE*F
SSCVKINVISTFLPLLVYTKSYYKLPGDSISSFI
IHYLSHFFPSNLLLS*EKRSAQTVIKRTEDPTL
SGVSCLCNFSMLSHIIQEKTRHSAFFLHRYHVL
RNCQLLRDNKQPEFLFISLHIVQEFMIKCCPHQM
LHPES*YMWIWIAFMHK*K*SQIQS*KTNL*GF
NRNIWWLPATMKLGNLELRNL*MSEMQKKSVHS
WY*LMEKT*PATEKCLIRLQNYWKNLVQLLRDLD
LMKILWI*QKWLRRDYSSCKVMNFLR*LCRVMY
TIISL*TCLTSCTSDYLLDLRLQQRCGKPCIIS
WGSLAVLEWLLINCWQN*FLVSLNQINKQSYYLK
VVNILFIV*IT*RKYLVLAIKLPNVLKHWVSIV
CVISKPFHPKF*KKN*EFQLLSVSKSSVLERIT
PL*YSQDHLSEYNSLQIKNC*YKSELNGSN*GQE
SFSEEDSFKKCSSEVEAKNKIEELLASLLNRVC
QDGRKPHTVRLIIRRYSSEKHYGRESRQCPIPS
HVIQKLGTGNYDVMTPMVDILMKLFRNMVNVKMP
FHLTLLSVCFCNLKALNTAKKGLIDYYLMPSLS
TTSRSGKHSFKMKDTHMEDFPKDKETNRDFLPS
GRIESTRTRESPLDTTNFSKEKDINEFPLCSLPE
GVDQEVFKQLPVDIQEEILSGKSREKFQGKGSV
SCPLHASRGVLSFFSKKQMQDIPINPRDHLSSS
KQVSSVSPCEPGTSGFNSSSSSYMSSQKDYSYYL
DNRLKDERISQGPKEPQGFHFTNSNPAVSAFHS
FPNLQSEQLFSRNHTTDSHKQTVATDSHEGLTE
NREPDSVDEKITFPSDIDPQVFYELPEAVQKELL
AEWKRAGSDFHIGHK*AYSAKRSEKQGNTIIFG
LAVY*ALLY*TLIDIQ*RSKLFQIKQE*LQEVN
SGTKRKNITEEIM*NTIFYV*SHFILLFNKKNIM
VN

Frame 2

RRGRRRGLGHGTGGRGGGSQLAGCAAARGASGL
LGCK*EGWGRRTLGAAATGARPSPPHSAPLREG
CLPLPCVTRRVPLEEWLHPAGVGWGASTLQIRV
EGLSAPSFPL*GARWGGNPSASPTKTAEASGPFN
FGEVEDLVAHLAEGGTRISVLAGRDGSEPRRSQ
VRCGHVSGDPLPALVFTLYRPPQGLDVKAPVLI
SCWFCFIH*FRDKVSLQPRTPGLK*SSAPASPSR
VAGTAGTCHHTWLIFRFF*IRCSCVVQAGLKLQ
PQAILPPQLRKVLGLQ*LAIVPGLLNFGTLGLP
ESCRARSP*C*HKLSTFVKTRKLTLV*YY*LNYT
LY*YSTSFSANVHFLFQDPNQNIVLYFACLVFS
QC*EKESPLSFPPRQIMT*QLFKIKELFSLSI*
*IFIGGLLCPRHCFRHWRFSIKPDNPAAMGAKNS
PHLYPLVVFCHFVFQFLLVCLF*M*GHAA*NNF
QAV*KSTSFQLFCPFWFTLRATINFQVIVLALS
SSIIYHIFSLQTYYYPEKNAVHKQ*LRGLKTLP*
VEFHVFVIFRCFHT*SRRKHVTLHSSFTGTMF*
GTVSCSEIISSLNFFLFLCILCRSS*SSVAHTK
CFIQSHSTCGSGLLLCTSRNDLKSRAKRQTFRGS
TEIFGGYLQL*S*ETWS*ETYECQRCKRKVSTV
GIS*WRRPDPLQRNVL*GYRITGRI*SSC*ETW
I**KFCGSNRNG*EETTAAAK**TFCGDCVGSCI
Q*SVYKPA*RLAHQTTCWISDCSRDAGSHV*SV
GAHWLCWSGF**TVGKISFWCL*TKSTNSLIT*
KLSTSYS*FESHKGNTWYWL*NCQMS*STGYQ*C
A*SPNLFTQNFRKRIRNFSCSAYPKAQFWRG*L
PCDTLRTTSVSTIACR*KTVNIKVN*MAQTKDK
S
PLVKKIHLKNVHLKLKLKIRLKNYLLVF*TEYA
KMEGSLIQ*D**SVGIPLRSTMVVRVVSALFLH
M*FRN*GQEIMM**PQWLIYL*NFFEIW*M*RC
HFTLPF*VCASATLKH*ILLRKGLLIII*CHHYQ
LLHALASTVLK*KTLIWKIFPKTKKQTGISYQV
EELKVQELGSLH*IPQIFLKKKTLMNSHSVHFL
KVLTKKSSSSFQ*IFKKKSFLENLGKNFKGKEV*
VVHYMPLEEYYLSFLKNKCKIFP*ILEIIYPVA
NRYPLYLLVNREHQALIAVVLLTCLAKRIIHII
*IID*KMNE*VKDLKNLKDSTLQIQTLLCLLFIH
FQTCRVSNFSPETTLQIAISKQ*QQTLMKDLQK
IESQILLMRKLLSLLTLILKFSMNYQKQYKRNC
WQSGREQDQISTLDINKHIQQKGLKSKGIPLFSD
*RFIKLFYIKH**IFNNGVNCSR*SKNSCKK*I
LAQSVKI*QKK*CKILSFMSKAILYYFSIKRIS
WST

Sequence POLI.eAug05

TAAGTTAGCTACTATGATTGAAGACAGTGCAACTTAATTTTAATAGCCTATAATGCATATATGAGGCAAAATATTTTAATCTGTTAAAAATCTTGTTTTC
AGAGTAGTCCAGTGATTTAGCAAATGGGAAAGGTATAATCACCCAGTTAACATTGACTGATTTTTTTGCTATGGGACAAGCACTTTACTGAGTGCTTTAA
ATATGTTAGTCCATTTAATCTTCACAACAAAGCATCAAGGTAGGTAGTACTGTTGTTTGTCCATTCCTTCTTACTTCTCTTCTTTCCTTCCTTCCTTCCA
TTCTCTCTCTCTCAAGATGAGGATACCGTACTTTAGAAAGGTTAAATAACTTGTCCAAGGATAAACTTAGATTCAAGTCCTAGGTGATTAAGAACTCTTG
CCATAATCATACAATAAAGCTTGGAGTTGGTACTAGAGCTTTAGAGTTTTCATAACTTTGAATTATTTTATATTAACTGTTTTATATTAACTGTTAATAC
AGTAATATTTTATATTAACTTTCTAGTGAGTACAATAGCTTGCAGATAAAAAACTGTTAATATAAAAGTGAACTAAATGGCTCAAACTAAGGACAAGAGG
TAAGTTAGTGAAGAATGTATTGAATATTTATTTGACTGTACACTGATAATAATTAGATATAGTTATTTGAGTTTGTGCTAATCCTTATTTATGCTTCTTT
GATAG
TCCTTTAGTGAAGAAGATTCATTTAAAAAATGTTCATCTGAAGTTGAAGCTAAAAATAAGATTGAAGAACTACTTGCTAGTCTTTTAAACAGAGT
ATGCCAAGATGGAAGGAAGCCTCATACAGTGAGATTAATAATCCGTCGGTATTCCTCTGAGAAGCACTATGGTCGTGAGAGTCGTCAGTGCCCTATTCCT
TCACATGTAATTCAGAAATTAGGGACAGGAAATTATGATGTGATGACCCCAATGGTTGATATACTTATGAAACTTTTTCGAAATATGGTGAATGTGAAGA
TGCCATTTCACCTTACCCTTCTAAGTGTGTGCTTCTGCAACCTTAAAGCACTAAATACTGCTAAGAAAGGGCTTATTGATTATTATTTAATGCCATCATT
ATCAACTACTTCACGCTCTGGCAAGCACAGTTTTAAAATGAAAGACACTCATATGGAAGATTTTCCCAAAGACAAAGAAACAAACCGGGATTTCCTACCA
AGTGGAAGAATTGAAAGTACAAGAACTAGGGAGTCTCCACTAGATACCACAAATTTTTCTAAAGAAAAAGACATTAATGAATTCCCACTCTGTTCACTTC
CTGAAGGTGTTGACCAAGAAGTCTTCAAGCAGCTTCCAGTAGATATTCAAGAAGAAATCCTTTCTGGAAAATCTAGGGAAAAATTTCAAGGGAAAGGAAG
TGTGAGTTGTCCATTACATGCCTCTAGAGGAGTATTATCTTTCTTTTCTAAAAAACAAATGCAAGATATTCCCATAAATCCTAGAGATCATTTATCCAGT
AGCAAACAGGTATCCTCTGTATCTCCTTGTGAACCGGGAACATCAGGCTTTAATAGCAGTAGTTCTTCTTACATGTCTAGCCAAAAGGATTATTCATATT
ATTTAGATAATAGATTAAAAGATGAACGAATAAGTCAAGGACCTAAAGAACCTCAAGGATTCCACTTTACAAATTCAAACCCTGCTGTGTCTGCTTTTCA
TTCATTTCCAAACTTGCAGAGTGAGCAACTTTTCTCCAGAAACCACACTACAGATAGCCATAAGCAAACAGTAGCAACAGACTCTCATGAAGGACTTACA
GAAAATAGAGAGCCAGATTCTGTTGATGAGAAAATTACTTTCCCTTCTGACATTGATCCTCAAGTTTTCTATGAACTACCAGAAGCAGTACAAAAGGAAC
TGCTGGCAGAGTGGAAGAGAGCAGGATCAGATTTCCACATTGGACATAAATAAGCATATTCAGCAAAAAGGTCTGAAAAGCAAGGGAATACCATTATTTT
CGGATTAGCGGTTTATTAAGCTCTTCTATATTAAACACTAATAGATATTCAATAACGGAGTAAACTGTTCCAGATAAAGCAAGAATAGTTGCAAGAAGTA
AATTCTGGCACAAAGCGTAAAAATATAACAGAAGAAATAATGTAAAATACTATCTTTTATGTCTAAAGCCATTTTATATTACTTTTCAATAAAAAGAATA
TCATGGTCAACAT
  • POLI.F8 (forward primer)
  • POLI.R14 (reverse primer)
  • Intron retention

Frame 0

*VSYYD*RQCNLILIAYNAYMRQNILIC*KSCF
QSSPVI*QMGKV*SPS*H*LIFLLWDKHFTECFK
YVSPFNLHNKASR*VVLLFVHSFLLLFFPSFLP
FSLSQDEDTVL*KG*ITCPRINLDSSPR*LRTL
AIIIQ*SLELVLEL*SFHNFELFYINCFILTVNT
VIFYINFLVSTIACR*KTVNIKVN*MAQTKDKR
*VSEECIEYLFDCTLIIIRYSYLSLC*SLFMLL
**
SFSEEDSFKKCSSEVEAKNKIEELLASLLNRV
CQDGRKPHTVRLIIRRYSSEKHYGRESRQCPIP
SHVIQKLGTGNYDVMTPMVDILMKLFRNMVNVK
MPFHLTLLSVCFCNLKALNTAKKGLIDYYLMPSL
STTSRSGKHSFKMKDTHMEDFPKDKETNRDFLP
SGRIESTRTRESPLDTTNFSKEKDINEFPLCSL
PEGVDQEVFKQLPVDIQEEILSGKSREKFQGKGS
VSCPLHASRGVLSFFSKKQMQDIPINPRDHLSS
SKQVSSVSPCEPGTSGFNSSSSSYMSSQKDYSY
YLDNRLKDERISQGPKEPQGFHFTNSNPAVSAFH
SFPNLQSEQLFSRNHTTDSHKQTVATDSHEGLT
ENREPDSVDEKITFPSDIDPQVFYELPEAVQKE
LLAEWKRAGSDFHIGHK*AYSAKRSEKQGNTIIF
GLAVY*ALLY*TLIDIQ*RSKLFQIKQE*LQEV
NSGTKRKNITEEIM*NTIFYV*SHFILLFNKKN
IMVN

Frame 1

KLATMIEDSAT*F**PIMHI*GKIF*SVKNLVF
RVVQ*FSKWERYNHPVNID*FFCYGTSTLLSAL
NMLVHLIFTTKHQGR*YCCLSIPSYFSSFLPSFH
SLSLKMRIPYFRKVK*LVQG*T*IQVLGD*ELL
P*SYNKAWSWY*SFRVFITLNYFILTVLY*LLI
Q*YFILTF**VQ*LADKKLLI*K*TKWLKLRTRG
KLVKNVLNIYLTVH***LDIVI*VCANPYLCFF
DS
PLVKKIHLKNVHLKLKLKIRLKNYLLVF*TE
YAKMEGSLIQ*D**SVGIPLRSTMVVRVVSALFL
HM*FRN*GQEIMM**PQWLIYL*NFFEIW*M*R
CHFTLPF*VCASATLKH*ILLRKGLLIII*CHH
YQLLHALASTVLK*KTLIWKIFPKTKKQTGISYQ
VEELKVQELGSLH*IPQIFLKKKTLMNSHSVHF
LKVLTKKSSSSFQ*IFKKKSFLENLGKNFKGKE
V*VVHYMPLEEYYLSFLKNKCKIFP*ILEIIYPV
ANRYPLYLLVNREHQALIAVVLLTCLAKRIIHI
I*IID*KMNE*VKDLKNLKDSTLQIQTLLCLLF
IHFQTCRVSNFSPETTLQIAISKQ*QQTLMKDLQ
KIESQILLMRKLLSLLTLILKFSMNYQKQYKRN
CWQSGREQDQISTLDINKHIQQKGLKSKGIPLF
SD*RFIKLFYIKH**IFNNGVNCSR*SKNSCKK*
ILAQSVKI*QKK*CKILSFMSKAILYYFSIKRI
SWST

Frame 2

S*LL*LKTVQLNFNSL*CIYEAKYFNLLKILFS
E*SSDLANGKGIITQLTLTDFFAMGQALY*VL*
IC*SI*SSQQSIKVGSTVVCPFLLTSLLSFLPS
ILSLSR*GYRTLERLNNLSKDKLRFKS*VIKNSC
HNHTIKLGVGTRALEFS*L*IILY*LFYINC*Y
SNILY*LSSEYNSLQIKNC*YKSELNGSN*GQE
VS**RMY*IFI*LYTDNN*I*LFEFVLILIYASL
I
VL**RRFI*KMFI*S*S*K*D*RTTC*SFKQS
MPRWKEASYSEINNPSVFL*EALWS*ESSVPYS
FTCNSEIRDRKL*CDDPNG*YTYETFSKYGECED
AISPYPSKCVLLQP*STKYC*ERAY*LLFNAII
INYFTLWQAQF*NERHSYGRFSQRQRNKPGFPT
KWKN*KYKN*GVSTRYHKFF*RKRH**IPTLFTS
*RC*PRSLQAASSRYSRRNPFWKI*GKISRERK
CELSITCL*RSIIFLF*KTNARYSHKS*RSFIQ
*QTGILCISL*TGNIRL**Q*FFLHV*PKGLFIL
FR**IKR*TNKSRT*RTSRIPLYKFKPCCVCFS
FISKLAE*ATFLQKPHYR*P*ANSSNRLS*RTY
RK*RARFC**ENYFPF*H*SSSFL*TTRSSTKGT
AGRVEESRIRFPHWT*ISIFSKKV*KAREYHYF
RISGLLSSSILNTNRYSITE*TVPDKARIVARS
KFWHKA*KYNRRNNVKYYLLCLKPFYITFQ*KEY
HGQH

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