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Sequences

Sequence UTRN.gAug05

GTGAAGTAGAGTGAGCATTAGCCTGGCAGACAGCTAGGGTAATAGATGACTTCCAGTGGAAGTCAAAGCACAAATGTTGGAAGAAGAAGAATGGTATAGA AGCCTTAAGCATTTTAACTATGATGTCTGCCAGAGTTGTTTCTTTTCGGGTCGAACAGCAAAAGGTCACAAATTACATTACCCAATGGTGGAATATTGTA TACCTACAACATCTGGGGAAGATGTACGAGACTTCACAAAGGTACTTAAGAACAAGTTCAGGTCGAAGAAGTACTTTGCCAAACACCCTCGACTTGGTTA CCTGCCTGTCCAGACAGTTCTTGAAGGTGACAACTTAGAGACCCCCTCACAATCTCCTCAACTGTTTCATGATGACACCCATTCAAGAATAGAACAATAT GCCACACGACTGGCCCAGATGGAAAGGACTAATGGGTCTTTTCTCACTGATAGCAGCTCCACCACAGGAAGTGTGGAAGACGAGCACGCCCTCATCCAGC AGTATTGCCAAACACTCGGAGGAGAGTCCCCAGTGAGCCAGCCGCAGAGCCCAGCTCAGATCCTGAAGTCAGTAGAGAGGGAAGAACGTGGAGAACTGGA GAGGATCATTGCTGACCTGGAGGA

UTRN.u.f.80 (forward primer)
UTRN.u.r.77 (reverse primer)
Single exon skipping

Frame 0

VK*SEH*PGRQLG**MTSSGSQSTNVGRRRMV* KP*AF*L*CLPELFLFGSNSKRSQITLPNGGILY TYNIWGRCTRLHKGT*EQVQVEEVLCQTPSTWL PACPDSS*R*QLRDPLTISSTVS**HPFKNRTI CHTTGPDGKD*WVFSH**QLHHRKCGRRARPHPA VLPNTRRRVPSEPAAEPSSDPEVSREGRTWRTG EDHC*PGG

Frame 1

*SRVSISLADS*GNR*LPVEVKAQMLEEEEWYR SLKHFNYDVCQSCFFSGRTAKGHKLHYPMVEYC IPTTSGEDVRDFTKVLKNKFRSKKYFAKHPRLGY LPVQTVLEGDNLETPSQSPQLFHDDTHSRIEQY ATRLAQMERTNGSFLTDSSSTTGSVEDEHALIQ QYCQTLGGESPVSQPQSPAQILKSVEREERGELE RIIADLE

Frame 2

EVE*ALAWQTARVIDDFQWKSKHKCWKKKNGIE ALSILTMMSARVVSFRVEQQKVTNYITQWWNIV YLQHLGKMYETSQRYLRTSSGRRSTLPNTLDLV TCLSRQFLKVTT*RPPHNLLNCFMMTPIQE*NNM PHDWPRWKGLMGLFSLIAAPPQEVWKTSTPSSS SIAKHSEESPQ*ASRRAQLRS*SQ*RGKNVENW RGSLLTWR

Sequence UTRN.cAug05

AGAAGATTATGAAGCAACAACACTAGCTACAGTTTAAATGAAGGCATTTCTTCACTTTTAATATATTTCTTTTTTCACCAGAATAACAATAAACCAGAAA TAAGTGTGAAAGAGTTTATAGATTGGATGCATTTGGAACCACAGTCCATGGTTTGGCTCCCAGTTTTACATCGAGTGGCAGCAGCGGAGACTGCAAAACA TCAGGCCAAATGCAACATCTGTAAAGAATGTCCAATTGTCGGGTTCAGGTATAGAAGCCTTAAGCATTTTAACTATGATGTCTGCCAGAGTTGTTTCTTT TCGGGTCGAACAGCAAAAGGTCACAAATTACATTACCCAATGGTGGAATATTGTATACCTACAACATCTGGGGAAGATGTACGAGACTTCACAAAGGTAC TTAAGAACAAGTTCAGGTCGAAGAAGTACTTTGCCAAACACCCTCGACTTGGTTACCTGCCTGTCCAGACAGTTCTTGAAGGTGACAACTTAGAGACCCC CTCACAATCTCCTCAACTGTTTCATGATGACACCCATTCAAGAATAGAACAATATGCCACACGACTGGCCCAGATGGAAAGGACTAATGGGTCTTTTCTC ACTGATAGCAGCTCCACCACAGGAAGTGTGGAAGACGAGCACGCCCTCATCCAGCAGTATTGCCAAACACTCGGAGGAGAGTCCCCAGTGAGCCAGCCGC AGAGCCCAGCTCAGATCCTGAAGTCAGTAGAGAGGGAAGAACGTGGAGAACTGGAGAGGATCATTGCTGACCTGGAGGAAGAACAAAGAAATCTACAGGT GGAGTATGAGCAGCTGAAGGACCAGCACCTCCGAAGGGGGCTCCCTGTCGGCTGGAGGCTAGGATGCAGATTTTAGAAGATCACAATAAACAGCTGGAGT CTCAGCTCCACCGCCTCCGACAGCTGCTGGAGCAGCCTGAATCTGATTCCCGAATCAATGGTGTTTCCCCATGGGCTTCTCCTCAGCATTCTGCACTGAG CTACTCGCTTGATCCAGATGCCTCCGGCCCACAGTTCCACCAGGCAGCGGGAGAGGACCTGCTGGCCCCACCGCACGACACCAGCACGGATCTCACGGAG GTCATGGAGCAGATTCACAGCACGTTTCCATCTTGCTGCCCAAATGTTCCCAGCAGGCCACAGGCAATGTGAAGTATTCATCCGGCCAACCAATGTTTCC TGACGTACAGTGTTGCCCTTTTCAGCAAATGCCAATTCCAAGTTCCATTAAATCAGAAGCTCCATGGCTCCTTGGCCCACGATGTTGAGTGCTGACTGTG TGTTCTACTGAAAGAGTAAAACACTGACTATCCAAAGAGAAATGGATATTTTGTTTTTATAATAACCATATATTATTGTTTTCTTCTTCCCTTTCTATGC AAGTGTAAATTAATGAACAGAGAGGTATTTGGAAATGGTAATACATTTGTCACGGATTTGTATAATGTATACAGCATTGGGAAAGTGGGTGGGGGCTTTC TAATATGATACCGTCTTTTTAATAACTATGACAAAGCTTACATAAGAATTAGAAGACCACTTTACATTTTTACATTCCTTCTGCTGTTCATATTAACCTT GCACAATTACTTCATTTTTTCTTTGACTCTTTTACCACAATGTTTTGGTTATTTATAATTTATCAGCCATATGTTTATCAGCCATATAACCAACTAGATC CCAAATAGATCCATGTATTTGTTTCCGTGATTTGGCCACATTAATAAATTCATAAATTTCAATCAAATATCTTATATATACACACATATGGTTTAAGCTA CAGCCCTGTGTATGCCGTTTAACTTTATTTGACGTTGCCCACTTACTTCTTTGCTGACCACTTGGATAACCGTAATAAAAATCCTATAAGCCTAAATGGC ATTTCTTTTGGGATATTTTTCCTGCATTTTATTCCCTTTTTATATAAGTAGGAATTAATTATTTATTTTATGTCTTAATCTATTTGATAAAGAAGACTAC ATTATAATAATCTCAAAGATCATATTACCAAAGGTTGCCCACTTGAGCATATTTTCATTTTGACACAGAAACAAAATTTAGTACAACCTTTCCTAGTTCC CATGTCTTGATTTTCATCATTACATGCACAGCAGACCTTTACCTATTGTGATACCAGAACACATCATTGTCTTTGGTTCCCTTCAAAGAGAATTTTATTG TTGTTTTGTATTTTCAAGTCCTTAATAGTTCTTGAAACTCCTAGTTGTTTTCTTGTTGAAAGCAGACACACATTTAGTGCACGGCTTATTTTACCTTTCG GGTGAAAGATCAGATGTTTTTATACCCTTCACTTGATCAATATATTTGGAAAGAATGTTTATCAAAAGTCTATGTCACTGCTTCTACAGAAGAATGAAAT TAATGCTTAGGTGATGGTACCTCCACCTACATCTTTTTGAGTGCATTCAATTATGTATTTTGGTTTAGCTTCTGATTTAACATTTAATTGATTCAGTTTA AACATGTTACTTAATTAGCAAATGTAGAGGAACCAAAAAAAGGTGAAAATAATATGTTTTGATTCAAACCTAAAGACATAAAAACATAAAGACATTTTAA CTTTGGGTTCTCTTTAGCTGGGATCTGGCCAGAAGGAGGCTTAAAGTTAGAAATTGCTATTATTTTAGAATAGGTTGGGTGGGTTGGGGGGCAAGGGTGT CTATTTGCAGCAGAGATATTTTGAAAAGAAGAAAATTGTTTTATATAAAAAGGAAAGCCATGACCACCTTTCTACCTCAGATCCATCTTCATCCATTGCA TTGGAAACTGCTTTATGCTGCTGCAGTCTGCAAAGTCTAGAGCTTTTATCAGGCCATGTCATACCCAAGAAAGCACCTATTTAAAGAAAAAACAATTCCC TGAGCTCTCAACTCCAAGTTGTAGATTTGGTGTCTTCCTTGTTCTTACTTTAAAAAGTCATGTGTTAATTTTTTTTCTGCCTGTATTTGTATGCAAAATG TCCTCTATCTGCTATTAAAGAAAAGCTACGTAAAACACTACATTGTAACCTTCTAAGTAATAATAAATAAAAAGAAATATATTGCAGTAACAATGGGAAG TAAGTATGTAGTTCTTTTGAAATATGTGGTAAAGAACTAATCACAGACTATCATCTAATCTGGTTACATATTGTATTTTTCATCCTGAATAAAAGTAATT TTAACACAAGA

UTRN.u.f.80 (forward primer)
UTRN.u.r.77 (reverse primer)
Single exon skipping

Frame 0

RRL*SNNTSYSLNEGISSLLIYFFFHQNNNKPE ISVKEFIDWMHLEPQSMVWLPVLHRVAAAETAKH QAKCNICKECPIVGFRYRSLKHFNYDVCQSCFF SGRTAKGHKLHYPMVEYCIPTTSGEDVRDFTKV LKNKFRSKKYFAKHPRLGYLPVQTVLEGDNLETP SQSPQLFHDDTHSRIEQYATRLAQMERTNGSFL TDSSSTTGSVEDEHALIQQYCQTLGGESPVSQP QSPAQILKSVEREERGELERIIADLEEEQRNLQV EYEQLKDQHLRRGLPVGWRLGCRF*KITINSWS LSSTASDSCWSSLNLIPESMVFPHGLLLSILH* ATRLIQMPPAHSSTRQRERTCWPHRTTPARISRR SWSRFTARFHLAAQMFPAGHRQCEVFIRPTNVS *RTVLPFSANANSKFH*IRSSMAPWPTMLSADC VFY*KSKTLTIQREMDILFL**PYIIVFFFPFYA SVN**TERYLEMVIHLSRICIMYTALGKWVGAF *YDTVFLITMTKLT*ELEDHFTFLHSFCCSY*P CTITSFFL*LFYHNVLVIYNLSAICLSAI*PTRS QIDPCICFRDLATLINS*ISIKYLIYTHIWFKL QPCVCRLTLFDVAHLLLC*PLG*P**KSYKPKW HFFWDIFPAFYSLFI*VGINYLFYVLIYLIKKTT L**SQRSYYQRLPT*AYFHFDTETKFSTTFPSS HVLIFIITCTADLYLL*YQNTSLSLVPFKENFI VVLYFQVLNSS*NS*LFSC*KQTHI*CTAYFTFR VKDQMFLYPSLDQYIWKECLSKVYVTASTEE*N *CLGDGTSTYIFLSAFNYVFWFSF*FNI*LIQF KHVT*LANVEEPKKGENNMF*FKPKDIKT*RHFN FGFSLAGIWPEGGLKLEIAIILE*VGWVGGQGC LFAAEIF*KEENCFI*KGKP*PPFYLRSIFIHC IGNCFMLLQSAKSRAFIRPCHTQESTYLKKKQFP ELSTPSCRFGVFLVLTLKSHVLIFFLPVFVCKM SSICY*RKAT*NTTL*PSK***IKRNILQ*QWE VSM*FF*NMW*RTNHRLSSNLVTYCIFHPE*K*F *HK

Frame 1

EDYEATTLATV*MKAFLHF*YISFFTRITINQK *V*KSL*IGCIWNHSPWFGSQFYIEWQQRRLQN IRPNATSVKNVQLSGSGIEALSILTMMSARVVSF RVEQQKVTNYITQWWNIVYLQHLGKMYETSQRY LRTSSGRRSTLPNTLDLVTCLSRQFLKVTT*RP PHNLLNCFMMTPIQE*NNMPHDWPRWKGLMGLFS LIAAPPQEVWKTSTPSSSSIAKHSEESPQ*ASR RAQLRS*SQ*RGKNVENWRGSLLTWRKNKEIYR WSMSS*RTSTSEGGSLSAGG*DADFRRSQ*TAGV SAPPPPTAAGAA*I*FPNQWCFPMGFSSAFCTE LLA*SRCLRPTVPPGSGRGPAGPTARHQHGSHG GHGADSQHVSILLPKCSQQATGNVKYSSGQPMFP DVQCCPFQQMPIPSSIKSEAPWLLGPRC*VLTV CSTERVKH*LSKEKWIFCFYNNHILLFSSSLSM QV*INEQRGIWKW*YICHGFV*CIQHWESGWGLS NMIPSF**L*QSLHKN*KTTLHFYIPSAVHINL AQLLHFFFDSFTTMFWLFIIYQPYVYQPYNQLD PK*IHVFVSVIWPH**IHKFQSNILYIHTYGLSY SPVYAV*LYLTLPTYFFADHLDNRNKNPISLNG ISFGIFFLHFIPFLYK*ELIIYFMS*SI**RRL HYNNLKDHITKGCPLEHIFILTQKQNLVQPFLVP MS*FSSLHAQQTFTYCDTRTHHCLWFPSKRILL LFCIFKSLIVLETPSCFLVESRHTFSARLILPF G*KIRCFYTLHLINIFGKNVYQKSMSLLLQKNEI NA*VMVPPPTSF*VHSIMYFGLASDLTFN*FSL NMLLN*QM*RNQKKVKIICFDSNLKT*KHKDIL TLGSL*LGSGQKEA*S*KLLLF*NRLGGLGGKGV YLQQRYFEKKKIVLYKKESHDHLSTSDPSSSIA LETALCCCSLQSLELLSGHVIPKKAPI*RKNNS LSSQLQVVDLVSSLFLL*KVMC*FFFCLYLYAKC PLSAIKEKLRKTLHCNLLSNNK*KEIYCSNNGK *VCSSFEICGKELITDYHLIWLHIVFFILNKSN FNTR

Frame 2

KIMKQQH*LQFK*RHFFTFNIFLFSPE*Q*TRN KCERVYRLDAFGTTVHGLAPSFTSSGSSGDCKT SGQMQHL*RMSNCRVQV*KP*AF*L*CLPELFL FGSNSKRSQITLPNGGILYTYNIWGRCTRLHKGT *EQVQVEEVLCQTPSTWLPACPDSS*R*QLRDP LTISSTVS**HPFKNRTICHTTGPDGKD*WVFS H**QLHHRKCGRRARPHPAVLPNTRRRVPSEPAA EPSSDPEVSREGRTWRTGEDHC*PGGRTKKSTG GV*AAEGPAPPKGAPCRLEARMQILEDHNKQLE SQLHRLRQLLEQPESDSRINGVSPWASPQHSALS YSLDPDASGPQFHQAAGEDLLAPPHDTSTDLTE VMEQIHSTFPSCCPNVPSRPQAM*SIHPANQCF LTYSVALFSKCQFQVPLNQKLHGSLAHDVEC*LC VLLKE*NTDYPKRNGYFVFIITIYYCFLLPFLC KCKLMNREVFGNGNTFVTDLYNVYSIGKVGGGF LI*YRLFNNYDKAYIRIRRPLYIFTFLLLFILTL HNYFIFSLTLLPQCFGYL*FISHMFISHITN*I PNRSMYLFP*FGHINKFINFNQISYIYTHMV*A TALCMPFNFI*RCPLTSLLTTWITVIKIL*A*MA FLLGYFSCILFPFYISRN*LFILCLNLFDKEDY IIIISKIILPKVAHLSIFSF*HRNKI*YNLS*F PCLDFHHYMHSRPLPIVIPEHIIVFGSLQREFYC CFVFSSP**FLKLLVVFLLKADTHLVHGLFYLS GERSDVFIPFT*SIYLERMFIKSLCHCFYRRMK LMLR*WYLHLHLFECIQLCILV*LLI*HLIDSV* TCYLISKCRGTKKR*K*YVLIQT*RHKNIKTF* LWVLFSWDLARRRLKVRNCYYFRIGWVGWGARV SICSRDILKRRKLFYIKRKAMTTFLPQIHLHPLH WKLLYAAAVCKV*SFYQAMSYPRKHLFKEKTIP *ALNSKL*IWCLPCSYFKKSCVNFFSACICMQN VLYLLLKKSYVKHYIVTF*VIINKKKYIAVTMGS KYVVLLKYVVKN*SQTII*SGYILYFSS*IKVI LTQ

Sequence UTRN.bAug05

AGATTGGATTAATGTCTCTCTCCAAAGGTCTCTTGGAAGAAAAATACAGATATCTCTTTAAGGAAGTTGCAGGGCCAACAGAAATGTGTGACCAGAGGCA GCTGGGCCTGTTACTTCATGATGCCATCCAGATCCCCCGGCAGCTAGGTGAAGTAGCAGCTTTTGGAGGCAGTAATATTGAGCCTAGTGTTCGCAGCTGC TTCCAACAGAATAACAATAAACCAGAAATAAGTGTGAAAGAGTTTATAGATTGGATGCATTTGGAACCACAGTCCATGGTTTGGCTCCCAGTTTTACATC GAGTGGCAGCAGCGGAGACTGCAAAACATCAGGCCAAATGCAACATCTGTAAAGAATGTCCAATTGTCGGGTTCAGGTATAGAAGCCTTAAGCATTTTAA CTATGATGTCTGCCAGAGTTGTTTCTTTTCGGGTCGAACAGCAAAAGGTCACAAATTACATTACCCAATGGTGGAATATTGTATACCTACAACATCTGGG GAAGATGTACGAGACTTCACAAAGGTACTTAAGAACAAGTTCAGGTCGAAGAAGTACTTTGCCAAACACCCTCGACTTGGTTACCTGCCTGTCCAGACAG TTCTTGAAGGTGACAACTTAGAGACCCCCTCACAATCTCCTCAACTGTTTCATGATGACACCCATTCAAGAATAGAACAATATGCCACACGACTGGCCCA GATGGAAAGGACTAATGGGTCTTTTCTCACTGATAGCAGCTCCACCACAGGAAGTGTGGAAGACGAGCACGCCCTCATCCAGCAGTATTGCCAAACACTC GGAGGAGAGTCCCCAGTGAGCCAGCCGCAGAGCCCAGCTCAGATCCTGAAGTCAGTAGAGAGGGAAGAACGTGGAGAACTGGAGAGGATCATTGCTGACC TGGAGGAAGAACAAAGAAATCTACAGGTGGAGTATGAGCAGCTGAAGGACCAGCACCTCCGAAGGGGGCTCCCTGTCGGTTCACCGCCAGAGTCGATTAT ATCTCCCCATCACACGTCTGAGGATTCAGAACTTATAGCAGAAGCAAAACTCCTCAGGCAGCACAAAGGTCGGCTGGAGGCTAGGATGCAGATTTTAGAA GATCACAATAAACAGCTGGAGTCTCAGCTCCACCGCCTCCGACAGCTGCTGGAGCAGCCTGAATCTGATTCCCGAATCAATGGTGTTTCCCCATGGGCTT CTCCTCAGCATTCTGCACTGAGCTACTCGCTTGATCCAGATGCCTCCGGCCCACAGTTCCACCAGGCAG

UTRN.u.f.80 (forward primer)
UTRN.u.r.77 (reverse primer)
Single exon skipping

Frame 0

RLD*CLSPKVSWKKNTDISLRKLQGQQKCVTRG SWACYFMMPSRSPGS*VK*QLLEAVILSLVFAAA SNRITINQK*V*KSL*IGCIWNHSPWFGSQFYI EWQQRRLQNIRPNATSVKNVQLSGSGIEALSIL TMMSARVVSFRVEQQKVTNYITQWWNIVYLQHLG KMYETSQRYLRTSSGRRSTLPNTLDLVTCLSRQ FLKVTT*RPPHNLLNCFMMTPIQE*NNMPHDWP RWKGLMGLFSLIAAPPQEVWKTSTPSSSSIAKHS EESPQ*ASRRAQLRS*SQ*RGKNVENWRGSLLT WRKNKEIYRWSMSS*RTSTSEGGSLSVHRQSRL YLPITRLRIQNL*QKQNSSGSTKVGWRLGCRF*K ITINSWSLSSTASDSCWSSLNLIPESMVFPHGL LLSILH*ATRLIQMPPAHSSTRQ

Frame 1

DWINVSLQRSLGRKIQISL*GSCRANRNV*PEA AGPVTS*CHPDPPAAR*SSSFWRQ*Y*A*CSQL LPTE*Q*TRNKCERVYRLDAFGTTVHGLAPSFTS SGSSGDCKTSGQMQHL*RMSNCRVQV*KP*AF* L*CLPELFLFGSNSKRSQITLPNGGILYTYNIW GRCTRLHKGT*EQVQVEEVLCQTPSTWLPACPDS S*R*QLRDPLTISSTVS**HPFKNRTICHTTGP DGKD*WVFSH**QLHHRKCGRRARPHPAVLPNT RRRVPSEPAAEPSSDPEVSREGRTWRTGEDHC*P GGRTKKSTGGV*AAEGPAPPKGAPCRFTARVDY ISPSHV*GFRTYSRSKTPQAAQRSAGG*DADFR RSQ*TAGVSAPPPPTAAGAA*I*FPNQWCFPMGF SSAFCTELLA*SRCLRPTVPPG

Frame 2

IGLMSLSKGLLEEKYRYLFKEVAGPTEMCDQRQ LGLLLHDAIQIPRQLGEVAAFGGSNIEPSVRSC FQQNNNKPEISVKEFIDWMHLEPQSMVWLPVLH RVAAAETAKHQAKCNICKECPIVGFRYRSLKHFN YDVCQSCFFSGRTAKGHKLHYPMVEYCIPTTSG EDVRDFTKVLKNKFRSKKYFAKHPRLGYLPVQT VLEGDNLETPSQSPQLFHDDTHSRIEQYATRLAQ MERTNGSFLTDSSSTTGSVEDEHALIQQYCQTL GGESPVSQPQSPAQILKSVEREERGELERIIAD LEEEQRNLQVEYEQLKDQHLRRGLPVGSPPESII SPHHTSEDSELIAEAKLLRQHKGRLEARMQILE DHNKQLESQLHRLRQLLEQPESDSRINGVSPWA SPQHSALSYSLDPDASGPQFHQA

Sequence UTRN.dAug05

UTRN.u.f.80 (forward primer)
UTRN.u.r.77 (reverse primer)
Single exon skipping

Frame 0

RRL*SNNTSYSLNEGISSLLIYFFFHQNNNKPE ISVKEFIDWMHLEPQSMVWLPVLHRVAAAETAKH QAKCNICKECPIVGFRYRSLKHFNYDVCQSCFF SGRTAKGHKLHYPMVEYCIPTTSGEDVRDFTKV LKNKFRSKKYFAKHPRLGYLPVQTVLEGDNLETP ITLISMWPEHYDPSQSPQLFHDDTHSRIEQYAT RLAQMERTNGSFLTDSSSTTGSVEDEHALIQQY CQTLGGESPVSQPQSPAQILKSVEREERGELERI IADLE

Frame 1

EDYEATTLATV*MKAFLHF*YISFFTRITINQK *V*KSL*IGCIWNHSPWFGSQFYIEWQQRRLQN IRPNATSVKNVQLSGSGIEALSILTMMSARVVSF RVEQQKVTNYITQWWNIVYLQHLGKMYETSQRY LRTSSGRRSTLPNTLDLVTCLSRQFLKVTT*RL LSHSSVCGQSTMTPHNLLNCFMMTPIQE*NNMPH DWPRWKGLMGLFSLIAAPPQEVWKTSTPSSSSI AKHSEESPQ*ASRRAQLRS*SQ*RGKNVENWRG SLLTWR

Frame 2

KIMKQQH*LQFK*RHFFTFNIFLFSPE*Q*TRN KCERVYRLDAFGTTVHGLAPSFTSSGSSGDCKT SGQMQHL*RMSNCRVQV*KP*AF*L*CLPELFL FGSNSKRSQITLPNGGILYTYNIWGRCTRLHKGT *EQVQVEEVLCQTPSTWLPACPDSS*R*QLRDS YHTHQYVARAL*PLTISSTVS**HPFKNRTICH TTGPDGKD*WVFSH**QLHHRKCGRRARPHPAVL PNTRRRVPSEPAAEPSSDPEVSREGRTWRTGED HC*PGG

Sequence UTRN.aAug05

GTGGCGCGATCGCCAAGCTCCCTGGCAGCGGCCCTGGAGAGACTGAGGGGACAGGAGGAGGGGGGCGCCCCATTGGTGTGTAGTCCCGCGCAGTCGCCGG CTCTCCTTTTCCGGACTCTGGGGATCTCTTGCTGCAACTGACAAGGTATTGATGTCAAGCTGAACCATCGTAGGAAGTTGAAAGCCTTAGAAAGAGGACT TGGTAAAGTTTTTGGATTATCTTGAAACTCTGGCAAGATGGCCAAGTATGGAGAACATGAAGCCAGTCCTGACAATGGGCAGAACGAATTCAGTGATATC ATTAAGTCCAGATCTGATGAACACAATGACGTACAGAAGAAAACCTTTACCAAATGGATAAATGCTCGATTTTCAAAGAGTGGGAAACCACCCATCAATG ATATGTTCACAGACCTCAAAGATGGAAGGAAGCTATTGGATCTTCTAGAAGGCCTCACAGGAACATCACTGCCAAAGGAACGTGGTTCCACAAGGGTACA TGCCTTAAATAACGTCAACAGAGTGCTGCAGGTTTTACATCAGAACAATGTGGAATTAGTGAATATAGGGGGAACTGACATTGTGGATGGAAATCACAAA CTGACTTTGGGGTTACTTTGGAGCATCATTTTGCACTGGCAGGTGAAAGATGTCATGAAGGATGTCATGTCGGACCTGCAGCAGACGAACAGTGAGAAGA TCCTGCTCAGCTGGGTGCGTCAGACCACCAGGCCCTACAGCCAAGTCAACGTCCTCAACTTCACCACCAGCTGGACAGATGGACTCGCCTTTAATGCTGT CCTCCACCGACATAAACCTGATCTCTTCAGCTGGGATAAAGTTGTCAAAATGTCACCAATTGAGAGACTTGAACATGCCTTCAGCAAGGCTCAAACTTAT TTGGGAATTGAAAAGCTGTTAGATCCTGAAGATGTTGCCGTTCAGCTTCCTGACAAGAAATCCATAATTATGTATTTAACATCTTTGTTTGAGGTGCTAC CTCAGCAAGTCACCATAGACGCCATCCGTGAGGTAGAGACACTCCCAAGGAAATATAAAAAAGAATGTGAAGAAGAGGCAATTAATATACAGAGTACAGC GCCTGAGGAGGAGCATGAGAGTCCCCGAGCTGAAACTCCCAGCACTGTCACTGAGGTTGACATGGATCTGGACAGCTATCAGATTGCGTTGGAGGAAGTG CTGACCTGGTTGCTTTCTGCTGAGGACACTTTCCAGGAGCAGGATGATATTTCTGATGATGTTGAAGAAGTCAAAGACCAGTTTGCAACCCATGAAGCTT TTATGATGGAACTGACTGCACACCAGAGCAGTGTGGGCAGCGTCCTGCAGGCAGGCAACCAACTGATAACACAAGGAACTCTGTCAGACGAAGAAGAATT TGAGATTCAGGAACAGATGACCCTGCTGAATGCTAGATGGGAGGCTCTTAGGGTGGAGAGTATGGACAGACAGTCCCGGCTGCACGATGTGCTGATGGAA CTGCAGAAGAAGCAACTGCAGCAGCTCTCCGCCTGGTTAACACTCACAGAGGAGCGCATTCAGAAGATGGAAACTTGCCCCCTGGATGATGATGTAAAAT CTCTACAAAAGCTGCTAGAAGAACATAAAAGTTTGCAAAGTGATCTTGAGGCTGAACAGGTGAAAGTAAATTCACTAACTCACATGGTGGTCATTGTTGA TGAAAACAGTGGTGAGAGTGCTACAGCTATCCTAGAAGACCAGTTACAGAAACTTGGTGAGCGCTGGACAGCAGTATGCCGTTGGACTGAAGAACGCTGG AATAGGTTACAAGAAATCAATATATTGTGGCAGGAATTATTGGAAGAACAGTGCTTGTTGAAAGCTTGGTTAACCGAAAAAGAAGAGGCTTTAAATAAAG TCCAGACAAGCAACTTCAAAGACCAAAAGGAACTAAGTGTCAGTGTTCGACGTCTGGCTATTTTGAAGGAAGACATGGAAATGAAGCGTCAAACATTGGA TCAGCTGAGTGAGATTGGCCAGGATGTGGGACAATTACTTGATAATTCCAAGGCATCTAAGAAGATCAACAGTGACTCAGAGGAACTGACTCAAAGATGG GATTCTTTGGTTCAGAGACTAGAAGATTCCTCCAACCAGGTGACTCAGGCTGTAGCAAAGCTGGGGATGTCTCAGATTCCTCAGAAGGACCTTTTGGAGA CTGTTCGTGTAAGAGAACAAGCAATTACAAAAAAATCTAAGCAGGAACTGCCTCCTCCTCCTCCCCCAAAGAAGAGACAGATCCATGTGGATATTGAAGC TAAGAAAAAGTTTGATGCTATAAGTGCAGAGCTGTTGAACTGGATTTTGAAATGGAAAACTGCCATTCAGACCACAGAGATAAAAGAGTATATGAAGATG CAAGACACTTCCGAAATGAAAAAGAAGTTGAAGGCATTAGAAAAAGAACAGAGAGAAAGAATCCCCAGAGCAGATGAATTAAACCAAACTGGACAAATCC TTGTGGAGCAAATGGGAAAAGAAGGCCTTCCTACTGAAGAAATAAAAAATGTTCTGGAGAAGGTTTCATCAGAATGGAAGAATGTATCTCAACATTTGGA AGATCTAGAAAGAAAGATTCAGCTACAGGAAGATATAAATGCTTATTTCAAGCAGCTTGATGAGCTTGAAAAGGTCATCAAGACAAAGGAGGAGTGGGTA AAACACACTTCCATTTCTGAATCTTCCCGGCAGTCCTTGCCAAGCTTGAAGGATTCCTGTCAGCGGGAATTGACAAATCTTCTTGGCCTTCACCCCAAAA TTGAAATGGCTCGTGCAAGCTGCTCGGCCCTGATGTCTCAGCCTTCTGCCCCAGATTTTGTCCAGCGGGGCTTCGATAGCTTTCTGGGCCGCTACCAAGC TGTACAAGAGGCTGTAGAGGATCGTCAACAACATCTAGAGAATGAACTGAAGGGCCAACCTGGACATGCATATCTGGAAACATTGAAAACACTGAAAGAT GTGCTAAATGATTCAGAAAATAAGGCCCAGGTGTCTCTGAATGTCCTTAATGATCTTGCCAAGGTGGAGAAGGCCCTGCAAGAAAAAAAGACCCTTGATG AAATCCTTGAGAATCAGAAACCTGCATTACATAAACTTGCAGAAGAAACAAAGGCTCTGGAGAAAAATGTTCATCCTGATGTAGAAAAATTATATAAGCA AGAATTTGATGATGTGCAAGGAAAGTGGAACAAGCTAAAGGTCTTGGTTTCCAAAGATCTACATTTGCTTGAGGAAATTGCTCTCACACTCAGAGCTTTT GAGGCCGATTCAACAGTCATTGAGAAGTGGATGGATGGCGTGAAAGACTTCTTAATGAAACAGCAGGCTGCCCAAGGAGACGACGCAGGTCTACAGAGGC AGTTAGACCAGTGCTCTGCATTTGTTAATGAAATAGAAACAATTGAATCATCTCTGAAAAACATGAAGGAAATAGAGACTAATCTTCGAAGTGGTCCAGT TGCTGGAATAAAAACTTGGGTGCAGACAAGACTAGGTGACTACCAAACTCAACTGGAGAAACTTAGCAAGGAGATCGCTACTCAAAAAAGTAGGTTGTCT GAAAGTCAAGAAAAAGCTGCGAACCTGAAGAAAGACTTGGCAGAGATGCAGGAATGGATGACCCAGGCCGAGGAAGAATATTTGGAGCGGGATTTTGAGT ACAAGTCACCAGAAGAGCTTGAGAGTGCTGTGGAAGAGATGAAGAGGGCAAAAGAGGATGTGTTGCAGAAGGAGGTGAGAGTGAAGATTCTCAAGGACAA CATCAAGTTATTAGCTGCCAAGGTGCCCTCTGGTGGCCAGGAGTTGACGTCTGAGCTGAATGTTGTGCTGGAGAATTACCAACTTCTTTGTAATAGAATT CGAGGAAAGTGCCACACGCTAGAGGAGGTCTGGTCTTGTTGGATTGAACTGCTTCACTATTTGGATCTTGAAACTACCTGGTTAAACACTTTGGAAGAGC GGATGAAGAGCACAGAGGTCCTGCCTGAGAAGACGGATGCTGTCAACGAAGCCCTGGAGTCTCTGGAATCTGTTCTGCGCCACCCGGCAGATAATCGCAC CCAGATTCGAGAGCTTGGCCAGACTCTGATTGATGGGGGGATCCTGGATGATATAATCAGTGAGAAACTGGAGGCTTTCAACAGCCGATATGAAGATCTA AGTCACCTGGCAGAGAGCAAGCAGATTTCTTTGGAAAAGCAACTCCAGGTGCTGCGGGAAACTGACCAGATGCTTCAAGTCTTGCAAGAGAGCTTGGGGG AGCTGGACAAACAGCTCACCACATACCTGACTGACAGGATAGATGCTTTCCAAGTTCCACAGGAAGCTCAGAAAATCCAAGCAGAGATCTCAGCCCATGA GCTAACCCTAGAGGAGTTGAGAAGAAATATGCGTTCTCAGCCCCTGACCTCCCCAGAGAGTAGGACTGCCAGAGGAGGAAGTCAGATGGATGTGCTACAG AGGAAACTCCGAGAGGTGTCCACAAAGTTCCAGCTTTTCCAGAAGCCAGCTAACTTCGAGCAGCGCATGCTGGACTGCAAGCGTGTGCTGGATGGCGTGA AAGCAGAACTTCACGTTCTGGATGTGAAGGACGTAGACCCTGACGTCATACAGACGCACCTGGACAAGTGTATGAAACTGTATAAAACTTTGAGTGAAGT CAAACTTGAAGTGGAAACTGTGATTAAAACAGGAAGACATATTGTCCAGAAACAGCAAACGGACAACCCAAAAGGGATGGATGAGCAGCTGACTTCCCTG AAGGTTCTTTACAATGACCTGGGCGCACAGGTGACAGAAGGAAAACAGGATCTGGAAAGAGCATCACAGTTGGCCCGGAAAATGAAGAAAGAGGCTGCTT CTCTCTCTGAATGGCTTTCTGCTACTGAAACTGAATTGGTACAGAAGTCCACTTCAGAAGGTCTGCTTGGTGACTTGGATACAGAAATTTCCTGGGCTAA AAATGTTCTGAAGGATCTGGAAAAGAGAAAAGCTGATTTAAATACCATCACAGAGAGTAGTGCTGCCCTGCAAAACTTGATTGAGGGCAGTGAGCCTATT TTAGAAGAGAGGCTCTGCGTCCTTAACGCTGGGTGGAGCCGAGTTCGTACCTGGACTGAAGATTGGTGCAATACCTTGATGAACCATCAGAACCAGCTAG AAATATTTGATGGGAACGTGGCTCACATAAGTACCTGGCTTTATCAAGCTGAAGCTCTATTGGATGAAATTGAAAAGAAACCAACAAGTAAACAGGAAGA AATTGTGAAGCGTTTAGTATCTGAGCTGGATGATGCCAACCTCCAGGTTGAAAATGTCCGCGATCAAGCCCTTATTTTGATGAATGCCCGTGGAAGCTCA AGCAGGGAGCTTGTAGAACCAAAGTTAGCTGAGCTGAATAGGAACTTTGAAAAGGTGTCTCAACATATCAAAAGTGCCAAATTGCTAATTGCTCAGGAAC CATTATACCAATGTTTGGTCACCACTGAAACATTTGAAACTGGTGTGCCTTTCTCTGACTTGGAAAAATTAGAAAATGACATAGAAAATATGTTAAAATT TGTGGAAAAACACTTGGAATCCAGTGATGAAGATGAAAAGATGGATGAGGAGAGTGCCCAGATTGAGGAAGTTCTACAAAGAGGAGAAGAAATGTTACAT CAACCTATGGAAGATAATAAAAAAGAAAAGATCCGTTTGCAATTATTACTTTTGCATACTAGATACAACAAAATTAAGGCAATCCCTATTCAACAGAGGA AAATGGGTCAACTTGCTTCTGGAATTAGATCATCACTTCTTCCTACAGATTATCTGGTTGAAATTAACAAAATTTTACTTTGCATGGATGATGTTGAATT ATCGCTTAATGTTCCAGAGCTCAACACTGCTATTTACGAAGACTTCTCTTTTCAGGAAGACTCTCTGAAGAATATCAAAGACCAACTGGACAAACTTGGA GAGCAGATTGCAGTCATTCATGAAAAACAGCCAGATGTCATCCTTGAAGCCTCTGGACCTGAAGCCATTCAGATCAGAGATACACTTACTCAGCTGAATG CAAAATGGGACAGAATTAATAGAATGTACAGTGATCGGAAAGGTTGTTTTGACAGGGCAATGGAAGAATGGAGACAGTTCCATTGTGACCTTAATGACCT CACACAGTGGATAACAGAGGCTGAAGAATTACTGGTTGATACCTGTGCTCCAGGTGGCAGCCTGGACTTAGAGAAAGCCAGGATACATCAGCAGGAACTT GAGGTGGGCATCAGCAGCCACCAGCCCAGTTTTGCAGCACTAAACCGAACTGGGGATGGGATTGTGCAGAAACTCTCCCAGGCAGATGGAAGCTTCTTGA AAGAAAAACTGGCAGGTTTAAACCAACGCTGGGATGCAATTGTTGCAGAAGTGAAGGATAGGCAGCCAAGGCTAAAAGGAGAAAGTAAGCAGGTGATGAA GTACAGGCATCAGCTAGATGAGATTATCTGTTGGTTAACAAAGGCTGAGCATGCTATGCAAAAGAGATCAACCACCGAATTGGGAGAAAACCTGCAAGAA TTAAGAGACTTAACTCAAGAAATGGAAGTACATGCTGAAAAACTCAAATGGCTGAATAGAACTGAATTGGAGATGCTTTCAGATAAAAGTCTGAGTTTAC CTGAAAGGGATAAAATTTCAGAAAGCTTAAGGACTGTAAATATGACATGGAATAAGATTTGCAGAGAGGTGCCTACCACCCTGAAGGAATGCATCCAGGA GCCCAGTTCTGTTTCACAGACAAGGATTGCTGCTCATCCTAATGTCCAAAAGGTGGTGCTAGTATCATCTGCGTCAGATATTCCTGTTCAGTCTCATCGT ACTTCGGAAATTTCAATTCCTGCTGATCTTGATAAAACTATAACAGAACTAGCCGACTGGCTGGTATTAATCGACCAGATGCTGAAGTCCAACATTGTCA CTGTTGGGGATGTAGAAGAGATCAATAAGACCGTTTCCCGAATGAAAATTACAAAGGCTGACTTAGAACAGCGCCATCCTCAGCTGGATTATGTTTTTAC ATTGGCACAGAATTTGAAAAATAAAGCTTCCAGTTCAGATATGAGAACAGCAATTACAGAAAAATTGGAAAGGGTCAAGAACCAGTGGGATGGCACCCAG CATGGCGTTGAGCTAAGACAGCAGCAGCTTGAGGACATGATTATTGACAGTCTTCAGTGGGATGACCATAGGGAGGAGACTGAAGAACTGATGAGAAAAT ATGAGGCTCGACTCTATATTCTTCAGCAAGCCCGACGGGATCCACTCACCAAACAAATTTCTGATAACCAAATACTGCTTCAAGAACTGGGTCCTGGAGA TGGTATCGTCATGGCGTTCGATAACGTCCTGCAGAAACTCCTGGAGGAATATGGGAGTGATGACACAAGGAATGTGAAAGAAACCACAGAGTACTTAAAA ACATCATGGATCAATCTCAAACAAAGTATTGCTGACAGACAGAACGCCTTGGAGGCTGAGTGGAGGACGGTGCAGGCCTCTCGCAGAGATCTGGAAAACT TCCTGAAGTGGATCCAAGAAGCAGAGACCACAGTGAATGTGCTTGTGGATGCCTCTCATCGGGAGAATGCTCTTCAGGATAGTATCTTGGCCAGGGAACT CAAACAGCAGATGCAGGACATCCAGGCAGAAATTGATGCCCACAATGACATATTTAAAAGCATTGACGGAAACAGGCAGAAGATGGTAAAAGCTTTGGGA AATTCTGAAGAGGCTACTATGCTTCAACATCGACTGGATGATATGAACCAAAGATGGAATGACTTAAAAGCAAAATCTGCTAGCATCAGGGCCCATTTGG AGGCCAGCGCTGAGAAGTGGAACAGGTTGCTGATGTCCTTAGAAGAACTGATCAAATGGCTGAATATGAAAGATGAAGAGCTTAAGAAACAAATGCCTAT TGGAGGAGATGTTCCAGCCTTACAGCTCCAGTATGACCATTGTAAGGCCCTGAGACGGGAGTTAAAGGAGAAAGAATATTCTGTCCTGAATGCTGTCGAC CAGGCCCGAGTTTTCTTGGCTGATCAGCCAATTGAGGCCCCTGAAGAGCCAAGAAGAAACCTACAATCAAAAACAGAATTAACTCCTGAGGAGAGAGCCC AAAAGATTGCCAAAGCCATGCGCAAACAGTCTTCTGAAGTCAAAGAAAAATGGGAAAGTCTAAATGCTGTAACTAGCAATTGGCAAAAGCAAGTGGACAA GGCATTGGAGAAACTCAGAGACCTGCAGGGAGCTATGGATGACCTGGACGCTGACATGAAGGAGGCAGAGTCCGTGCGGAATGGCTGGAAGCCCGTGGGA GACTTACTCATTGACTCGCTGCAGGATCACATTGAAAAAATCATGGCATTTAGAGAAGAAATTGCACCAATCAACTTTAAAGTTAAAACGGTGAATGATT TATCCAGTCAGCTGTCTCCACTTGACCTGCATCCCTCTCTAAAGATGTCTCGCCAGCTAGATGACCTTAATATGCGATGGAAACTTTTACAGGTTTCTGT GGATGATCGCCTTAAACAGCTTCAGGAAGCCCACAGAGATTTTGGACCATCCTCTCAGCATTTTCTCTCTACGTCAGTCCAGCTGCCGTGGCAAAGATCC ATTTCACATAATAAAGTGCCCTATTACATCAACCATCAAACACAGACCACCTGTTGGGACCATCCTAAAATGACCGAACTCTTTCAATCCCTTGCTGACC TGAATAATGTACGTTTTTCTGCCTACCGTACAGCAATCAAAATCCGAAGACTACAAAAAGCACTATGTTTGGATCTCTTAGAGTTGAGTACAACAAATGA AATTTTCAAACAGCACAAGTTGAACCAAAATGACCAGCTCCTCAGTGTTCCAGATGTCATCAACTGTCTGACAACAACTTATGATGGACTTGAGCAAATG CATAAGGACCTGGTCAACGTTCCACTCTGTGTTGATATGTGTCTCAATTGGTTGCTCAATGTCTATGACACGGGTCGAACTGGAAAAATTAGAGTGCAGA GTCTGAAGATTGGATTAATGTCTCTCTCCAAAGGTCTCTTGGAAGAAAAATACAGATATCTCTTTAAGGAAGTTGCAGGGCCAACAGAAATGTGTGACCA GAGGCAGCTGGGCCTGTTACTTCATGATGCCATCCAGATCCCCCGGCAGCTAGGTGAAGTAGCAGCTTTTGGAGGCAGTAATATTGAGCCTAGTGTTCGC AGCTGCTTCCAACAGAATAACAATAAACCAGAAATAAGTGTGAAAGAGTTTATAGATTGGATGCATTTGGAACCACAGTCCATGGTTTGGCTCCCAGTTT TACATCGAGTGGCAGCAGCGGAGACTGCAAAACATCAGGCCAAATGCAACATCTGTAAAGAATGTCCAATTGTCGGGTTCAGGTATAGAAGCCTTAAGCA TTTTAACTATGATGTCTGCCAGAGTTGTTTCTTTTCGGGTCGAACAGCAAAAGGTCACAAATTACATTACCCAATGGTGGAATATTGTATACCTACAACA TCTGGGGAAGATGTACGAGACTTCACAAAGGTACTTAAGAACAAGTTCAGGTCGAAGAAGTACTTTGCCAAACACCCTCGACTTGGTTACCTGCCTGTCC AGACAGTTCTTGAAGGTGACAACTTAGAGACTCCTATCACACTCATCAGTATGTGGCCAGAGCACTATGACCCCTCACAATCTCCTCAACTGTTTCATGA TGACACCCATTCAAGAATAGAACAATATGCCACACGACTGGCCCAGATGGAAAGGACTAATGGGTCTTTTCTCACTGATAGCAGCTCCACCACAGGAAGT GTGGAAGACGAGCACGCCCTCATCCAGCAGTATTGCCAAACACTCGGAGGAGAGTCCCCAGTGAGCCAGCCGCAGAGCCCAGCTCAGATCCTGAAGTCAG TAGAGAGGGAAGAACGTGGAGAACTGGAGAGGATCATTGCTGACCTGGAGGAAGAACAAAGAAATCTACAGGTGGAGTATGAGCAGCTGAAGGACCAGCA CCTCCGAAGGGGGCTCCCTGTCGGTTCACCGCCAGAGTCGATTATATCTCCCCATCACACGTCTGAGGATTCAGAACTTATAGCAGAAGCAAAACTCCTC AGGCAGCACAAAGGTCGGCTGGAGGCTAGGATGCAGATTTTAGAAGATCACAATAAACAGCTGGAGTCTCAGCTCCACCGCCTCCGACAGCTGCTGGAGC AGCCTGAATCTGATTCCCGAATCAATGGTGTTTCCCCATGGGCTTCTCCTCAGCATTCTGCACTGAGCTACTCGCTTGATCCAGATGCCTCCGGCCCACA GTTCCACCAGGCAGCGGGAGAGGACCTGCTGGCCCCACCGCACGACACCAGCACGGATCTCACGGAGGTCATGGAGCAGATTCACAGCACGTTTCCATCT TGCTGCCCAAATGTTCCCAGCAGGCCACAGGCAATGTGAAGTATTCATCCGGCCAACCAATGTTTCCTGACGTACAGTGTTGCCCTTTTCAGCAAATGCC AATTCCAAGTTCCATTAAATCAGAAGCTCCATGGCTCCTTGGCCCACGATGTTGAGTGCTGACTGTGTGTTCTACTGAAAGAGTAAAACACTGACTATCC AAAGAGAAATGGATATTTTGTTTTTATAATAACCATATATTATTGTTTTCTTCTTCCCTTTCTATGCAAGTGTAAATTAATGAACAGAGAGGTATTTGGA AATGGTAATACATTTGTCACGGATTTGTATAATGTATACAGCATTGGGAAAGTGGGTGGGGGCTTTCTAATATGATACCGTCTTTTTAATAACTATGACA AAGCTTACATAAGAATTAGAAGACCACTTTACATTTTTACATTCCTTCTGCTGTTCATATTAACCTTGCACAATTACTTCATTTTTTCTTTGACTCTTTT ACCACAATGTTTTGGTTATTTATAATTTATCAGCCATATGTTTATCAGCCATATAACCAACTAGATCCCAAATAGATCCATGTATTTGTTTCCGTGATTT GGCCACATTAATAAATTCATAAATTTCAATCAAATATCTTATATATACACACATATGGTTTAAGCTACAGCCCTGTGTATGCCGTTTAACTTTATTTGAC GTTGCCCACTTACTTCTTTGCTGACCACTTGGATAACCGTAATAAAAATCCTATAAGCCTAAATGGCATTTCTTTTGGGATATTTTTCCTGCATTTTATT CCCTTTTTATATAAGTAGGAATTAATTATTTATTTTATGTCTTAATCTATTTGATAAAGAAGACTACATTATAATAATCTCAAAGATCATATTACCAAAG GTTGCCCACTTGAGCATATTTTCATTTTGACACAGAAACAAAATTTAGTACAACCTTTCCTAGTTCCCATGTCTTGATTTTCATCATTACATGCACAGCA GACCTTTACCTATTGTGATACCAGAACACATCATTGTCTTTGGTTCCCTTCAAAGAGAATTTTATTGTTGTTTTGTATTTTCAAGTCCTTAATAGTTCTT GAAACTCCTAGTTGTTTTCTTGTTGAAAGCAGACACACATTTAGTGCACGGCTTATTTTACCTTTCGGGTGAAAGATCAGATGTTTTTATACCCTTCACT TGATCAATATATTTGGAAAGAATGTTTATCAAAAGTCTATGTCACTGCTTCTACAGAAGAATGAAATTAATGCTTAGGTGATGGTACCTCCACCTACATC TTTTTGAGTGCATTCAATTATGTATTTTGGTTTAGCTTCTGATTTAACATTTAATTGATTCAGTTTAAACATGTTACTTAATTAGCAAATGTAGAGGAAC CAAAAAAAGGTGAAAATAATATGTTTTGATTCAAACCTAAAGACATAAAAACATAAAGACATTTTAACTTTGGGTTCTCTTTAGCTGGGATCTGGCCAGA AGGAGGCTTAAAGTTAGAAATTGCTATTATTTTAGAATAGGTTGGGTGGGTTGGGGGGCAAGGGTGTCTATTTGCAGCAGAGATATTTTGAAAAGAAGAA AATTGTTTTATATAAAAAGGAAAGCCATGACCACCTTTCTACCTCAGATCCATCTTCATCCATTGCATTGGAAACTGCTTTATGCTGCTGCAGTCTGCAA AGTCTAGAGCTTTTATCAGGCCATGTCATACCCAAGAAAGCACCTATTTAAAGAAAAAACAATTCCCTGAGCTCTCAACTCCAAGTTGTAGATTTGGTGT CTTCCTTGTTCTTACTTTAAAAAGTCATGTGTTAATTTTTTTTCTGCCTGTATTTGTATGCAAAATGTCCTCTATCTGCTATTAAAGAAAAGCTACGTAA AACACTACATTGTAACCTTCTAAGTAATAATAAATAAAAAGAAATATATTGCAGTAACAATGGGAAGTAAGTATGTAGTTCTTTTGAAATATGTGGTAAA GAACTAATCACAGACTATCATCTAATCTGGTTACATATTGTATTTTTCATCCTGAATAAAAGTAATTTTAACACAAGA

UTRN.u.f.80 (forward primer)
UTRN.u.r.77 (reverse primer)
Single exon skipping

Frame 0

VARSPSSLAAALERLRGQEEGGAPLVCSPAQSP ALLFRTLGISCCN*QGIDVKLNHRRKLKALERGL GKVFGLS*NSGKMAKYGEHEASPDNGQNEFSDI IKSRSDEHNDVQKKTFTKWINARFSKSGKPPIN DMFTDLKDGRKLLDLLEGLTGTSLPKERGSTRVH ALNNVNRVLQVLHQNNVELVNIGGTDIVDGNHK LTLGLLWSIILHWQVKDVMKDVMSDLQQTNSEK ILLSWVRQTTRPYSQVNVLNFTTSWTDGLAFNAV LHRHKPDLFSWDKVVKMSPIERLEHAFSKAQTY LGIEKLLDPEDVAVQLPDKKSIIMYLTSLFEVL PQQVTIDAIREVETLPRKYKKECEEEAINIQSTA PEEEHESPRAETPSTVTEVDMDLDSYQIALEEV LTWLLSAEDTFQEQDDISDDVEEVKDQFATHEA FMMELTAHQSSVGSVLQAGNQLITQGTLSDEEEF EIQEQMTLLNARWEALRVESMDRQSRLHDVLME LQKKQLQQLSAWLTLTEERIQKMETCPLDDDVK SLQKLLEEHKSLQSDLEAEQVKVNSLTHMVVIVD ENSGESATAILEDQLQKLGERWTAVCRWTEERW NRLQEINILWQELLEEQCLLKAWLTEKEEALNK VQTSNFKDQKELSVSVRRLAILKEDMEMKRQTLD QLSEIGQDVGQLLDNSKASKKINSDSEELTQRW DSLVQRLEDSSNQVTQAVAKLGMSQIPQKDLLE TVRVREQAITKKSKQELPPPPPPKKRQIHVDIEA KKKFDAISAELLNWILKWKTAIQTTEIKEYMKM QDTSEMKKKLKALEKEQRERIPRADELNQTGQI LVEQMGKEGLPTEEIKNVLEKVSSEWKNVSQHLE DLERKIQLQEDINAYFKQLDELEKVIKTKEEWV KHTSISESSRQSLPSLKDSCQRELTNLLGLHPK IEMARASCSALMSQPSAPDFVQRGFDSFLGRYQA VQEAVEDRQQHLENELKGQPGHAYLETLKTLKD VLNDSENKAQVSLNVLNDLAKVEKALQEKKTLD EILENQKPALHKLAEETKALEKNVHPDVEKLYKQ EFDDVQGKWNKLKVLVSKDLHLLEEIALTLRAF EADSTVIEKWMDGVKDFLMKQQAAQGDDAGLQR QLDQCSAFVNEIETIESSLKNMKEIETNLRSGPV AGIKTWVQTRLGDYQTQLEKLSKEIATQKSRLS ESQEKAANLKKDLAEMQEWMTQAEEEYLERDFE YKSPEELESAVEEMKRAKEDVLQKEVRVKILKDN IKLLAAKVPSGGQELTSELNVVLENYQLLCNRI RGKCHTLEEVWSCWIELLHYLDLETTWLNTLEE RMKSTEVLPEKTDAVNEALESLESVLRHPADNRT QIRELGQTLIDGGILDDIISEKLEAFNSRYEDL SHLAESKQISLEKQLQVLRETDQMLQVLQESLG ELDKQLTTYLTDRIDAFQVPQEAQKIQAEISAHE LTLEELRRNMRSQPLTSPESRTARGGSQMDVLQ RKLREVSTKFQLFQKPANFEQRMLDCKRVLDGV KAELHVLDVKDVDPDVIQTHLDKCMKLYKTLSEV KLEVETVIKTGRHIVQKQQTDNPKGMDEQLTSL KVLYNDLGAQVTEGKQDLERASQLARKMKKEAA SLSEWLSATETELVQKSTSEGLLGDLDTEISWAK NVLKDLEKRKADLNTITESSAALQNLIEGSEPI LEERLCVLNAGWSRVRTWTEDWCNTLMNHQNQL EIFDGNVAHISTWLYQAEALLDEIEKKPTSKQEE IVKRLVSELDDANLQVENVRDQALILMNARGSS SRELVEPKLAELNRNFEKVSQHIKSAKLLIAQE PLYQCLVTTETFETGVPFSDLEKLENDIENMLKF VEKHLESSDEDEKMDEESAQIEEVLQRGEEMLH QPMEDNKKEKIRLQLLLLHTRYNKIKAIPIQQR KMGQLASGIRSSLLPTDYLVEINKILLCMDDVEL SLNVPELNTAIYEDFSFQEDSLKNIKDQLDKLG EQIAVIHEKQPDVILEASGPEAIQIRDTLTQLN AKWDRINRMYSDRKGCFDRAMEEWRQFHCDLNDL TQWITEAEELLVDTCAPGGSLDLEKARIHQQEL EVGISSHQPSFAALNRTGDGIVQKLSQADGSFL KEKLAGLNQRWDAIVAEVKDRQPRLKGESKQVMK YRHQLDEIICWLTKAEHAMQKRSTTELGENLQE LRDLTQEMEVHAEKLKWLNRTELEMLSDKSLSL PERDKISESLRTVNMTWNKICREVPTTLKECIQE PSSVSQTRIAAHPNVQKVVLVSSASDIPVQSHR TSEISIPADLDKTITELADWLVLIDQMLKSNIV TVGDVEEINKTVSRMKITKADLEQRHPQLDYVFT LAQNLKNKASSSDMRTAITEKLERVKNQWDGTQ HGVELRQQQLEDMIIDSLQWDDHREETEELMRK YEARLYILQQARRDPLTKQISDNQILLQELGPGD GIVMAFDNVLQKLLEEYGSDDTRNVKETTEYLK TSWINLKQSIADRQNALEAEWRTVQASRRDLEN FLKWIQEAETTVNVLVDASHRENALQDSILAREL KQQMQDIQAEIDAHNDIFKSIDGNRQKMVKALG NSEEATMLQHRLDDMNQRWNDLKAKSASIRAHL EASAEKWNRLLMSLEELIKWLNMKDEELKKQMPI GGDVPALQLQYDHCKALRRELKEKEYSVLNAVD QARVFLADQPIEAPEEPRRNLQSKTELTPEERA QKIAKAMRKQSSEVKEKWESLNAVTSNWQKQVDK ALEKLRDLQGAMDDLDADMKEAESVRNGWKPVG DLLIDSLQDHIEKIMAFREEIAPINFKVKTVND LSSQLSPLDLHPSLKMSRQLDDLNMRWKLLQVSV DDRLKQLQEAHRDFGPSSQHFLSTSVQLPWQRS ISHNKVPYYINHQTQTTCWDHPKMTELFQSLAD LNNVRFSAYRTAIKIRRLQKALCLDLLELSTTNE IFKQHKLNQNDQLLSVPDVINCLTTTYDGLEQM HKDLVNVPLCVDMCLNWLLNVYDTGRTGKIRVQ SLKIGLMSLSKGLLEEKYRYLFKEVAGPTEMCDQ RQLGLLLHDAIQIPRQLGEVAAFGGSNIEPSVR SCFQQNNNKPEISVKEFIDWMHLEPQSMVWLPV LHRVAAAETAKHQAKCNICKECPIVGFRYRSLKH FNYDVCQSCFFSGRTAKGHKLHYPMVEYCIPTT SGEDVRDFTKVLKNKFRSKKYFAKHPRLGYLPV QTVLEGDNLETPITLISMWPEHYDPSQSPQLFHD DTHSRIEQYATRLAQMERTNGSFLTDSSSTTGS VEDEHALIQQYCQTLGGESPVSQPQSPAQILKS VEREERGELERIIADLEEEQRNLQVEYEQLKDQH LRRGLPVGSPPESIISPHHTSEDSELIAEAKLL RQHKGRLEARMQILEDHNKQLESQLHRLRQLLE QPESDSRINGVSPWASPQHSALSYSLDPDASGPQ FHQAAGEDLLAPPHDTSTDLTEVMEQIHSTFPS CCPNVPSRPQAM*SIHPANQCFLTYSVALFSKC QFQVPLNQKLHGSLAHDVEC*LCVLLKE*NTDYP KRNGYFVFIITIYYCFLLPFLCKCKLMNREVFG NGNTFVTDLYNVYSIGKVGGGFLI*YRLFNNYD KAYIRIRRPLYIFTFLLLFILTLHNYFIFSLTLL PQCFGYL*FISHMFISHITN*IPNRSMYLFP*F GHINKFINFNQISYIYTHMV*ATALCMPFNFI* RCPLTSLLTTWITVIKIL*A*MAFLLGYFSCILF PFYISRN*LFILCLNLFDKEDYIIIISKIILPK VAHLSIFSF*HRNKI*YNLS*FPCLDFHHYMHS RPLPIVIPEHIIVFGSLQREFYCCFVFSSP**FL KLLVVFLLKADTHLVHGLFYLSGERSDVFIPFT *SIYLERMFIKSLCHCFYRRMKLMLR*WYLHLH LFECIQLCILV*LLI*HLIDSV*TCYLISKCRGT KKR*K*YVLIQT*RHKNIKTF*LWVLFSWDLAR RRLKVRNCYYFRIGWVGWGARVSICSRDILKRR KLFYIKRKAMTTFLPQIHLHPLHWKLLYAAAVCK V*SFYQAMSYPRKHLFKEKTIP*ALNSKL*IWC LPCSYFKKSCVNFFSACICMQNVLYLLLKKSYV KHYIVTF*VIINKKKYIAVTMGSKYVVLLKYVVK N*SQTII*SGYILYFSS*IKVILTQ

Frame 1

WRDRQAPWQRPWRD*GDRRRGAPHWCVVPRSRR LSFSGLWGSLAATDKVLMSS*TIVGS*KP*KED LVKFLDYLETLARWPSMENMKPVLTMGRTNSVIS LSPDLMNTMTYRRKPLPNG*MLDFQRVGNHPSM ICSQTSKMEGSYWIF*KASQEHHCQRNVVPQGY MP*ITSTECCRFYIRTMWN**I*GELTLWMEITN *LWGYFGASFCTGR*KMS*RMSCRTCSRRTVRR SCSAGCVRPPGPTAKSTSSTSPPAGQMDSPLML SSTDINLISSAGIKLSKCHQLRDLNMPSARLKLI WELKSC*ILKMLPFSFLTRNP*LCI*HLCLRCY LSKSP*TPSVR*RHSQGNIKKNVKKRQLIYRVQ RLRRSMRVPELKLPALSLRLTWIWTAIRLRWRKC *PGCFLLRTLSRSRMIFLMMLKKSKTSLQPMKL L*WN*LHTRAVWAASCRQATN**HKELCQTKKN LRFRNR*PC*MLDGRLLGWRVWTDSPGCTMC*WN CRRSNCSSSPPG*HSQRSAFRRWKLAPWMMM*N LYKSC*KNIKVCKVILRLNR*K*IH*LTWWSLL MKTVVRVLQLS*KTSYRNLVSAGQQYAVGLKNAG IGYKKSIYCGRNYWKNSAC*KLG*PKKKRL*IK SRQATSKTKRN*VSVFDVWLF*RKTWK*SVKHW IS*VRLARMWDNYLIIPRHLRRSTVTQRN*LKDG ILWFRD*KIPPTR*LRL*QSWGCLRFLRRTFWR LFV*ENKQLQKNLSRNCLLLLPQRRDRSMWILK LRKSLML*VQSC*TGF*NGKLPFRPQR*KSI*RC KTLPK*KRS*RH*KKNREKESPEQMN*TKLDKS LWSKWEKKAFLLKK*KMFWRRFHQNGRMYLNIW KI*KERFSYRKI*MLISSSLMSLKRSSRQRRSG* NTLPFLNLPGSPCQA*RIPVSGN*QIFLAFTPK LKWLVQAARP*CLSLLPQILSSGASIAFWAATK LYKRL*RIVNNI*RMN*RANLDMHIWKH*KH*KM C*MIQKIRPRCL*MSLMILPRWRRPCKKKRPLM KSLRIRNLHYINLQKKQRLWRKMFILM*KNYIS KNLMMCKESGTS*RSWFPKIYICLRKLLSHSELL RPIQQSLRSGWMA*KTS**NSRLPKETTQVYRG S*TSALHLLMK*KQLNHL*KT*RK*RLIFEVVQ LLE*KLGCRQD*VTTKLNWRNLARRSLLKKVGCL KVKKKLRT*RKTWQRCRNG*PRPRKNIWSGILS TSHQKSLRVLWKR*RGQKRMCCRRR*E*RFSRT TSSY*LPRCPLVARS*RLS*MLCWRITNFFVIEF EESATR*RRSGLVGLNCFTIWILKLPG*TLWKS G*RAQRSCLRRRMLSTKPWSLWNLFCATRQIIA PRFESLARL*LMGGSWMI*SVRNWRLSTADMKI* VTWQRASRFLWKSNSRCCGKLTRCFKSCKRAWG SWTNSSPHT*LTG*MLSKFHRKLRKSKQRSQPM S*P*RS*EEICVLSP*PPQRVGLPEEEVRWMCYR GNSERCPQSSSFSRSQLTSSSACWTASVCWMA* KQNFTFWM*RT*TLTSYRRTWTSV*NCIKL*VK SNLKWKL*LKQEDILSRNSKRTTQKGWMSS*LP* RFFTMTWAHR*QKENRIWKEHHSWPGK*RKRLL LSLNGFLLLKLNWYRSPLQKVCLVTWIQKFPGL KMF*RIWKREKLI*IPSQRVVLPCKT*LRAVSLF *KRGSASLTLGGAEFVPGLKIGAIP**TIRTS* KYLMGTWLT*VPGFIKLKLYWMKLKRNQQVNRK KL*SV*YLSWMMPTSRLKMSAIKPLF**MPVEAQ AGSL*NQS*LS*IGTLKRCLNISKVPNC*LLRN HYTNVWSPLKHLKLVCLSLTWKN*KMT*KIC*N LWKNTWNPVMKMKRWMRRVPRLRKFYKEEKKCYI NLWKIIKKKRSVCNYYFCILDTTKLRQSLFNRG KWVNLLLELDHHFFLQIIWLKLTKFYFAWMMLN YRLMFQSSTLLFTKTSLFRKTL*RISKTNWTNLE SRLQSFMKNSQMSSLKPLDLKPFRSEIHLLS*M QNGTELIECTVIGKVVLTGQWKNGDSSIVTLMT SHSG*QRLKNYWLIPVLQVAAWT*RKPGYISRNL RWASAATSPVLQH*TELGMGLCRNSPRQMEAS* KKNWQV*TNAGMQLLQK*RIGSQG*KEKVSR** STGIS*MRLSVG*QRLSMLCKRDQPPNWEKTCKN *ET*LKKWKYMLKNSNG*IELNWRCFQIKV*VY LKGIKFQKA*GL*I*HGIRFAERCLPP*RNASR SPVLFHRQGLLLILMSKRWC*YHLRQIFLFSLIV LRKFQFLLILIKL*QN*PTGWY*STRC*SPTLS LLGM*KRSIRPFPE*KLQRLT*NSAILSWIMFL HWHRI*KIKLPVQI*EQQLQKNWKGSRTSGMAPS MALS*DSSSLRT*LLTVFSGMTIGRRLKN**EN MRLDSIFFSKPDGIHSPNKFLITKYCFKNWVLE MVSSWRSITSCRNSWRNMGVMTQGM*KKPQST*K HHGSISNKVLLTDRTPWRLSGGRCRPLAEIWKT S*SGSKKQRPQ*MCLWMPLIGRMLFRIVSWPGN SNSRCRTSRQKLMPTMTYLKALTETGRRW*KLWE ILKRLLCFNIDWMI*TKDGMT*KQNLLASGPIW RPALRSGTGC*CP*KN*SNG*I*KMKSLRNKCL LEEMFQPYSSSMTIVRP*DGS*RRKNILS*MLST RPEFSWLISQLRPLKSQEETYNQKQN*LLRREP KRLPKPCANSLLKSKKNGKV*ML*LAIGKSKWT RHWRNSETCRELWMTWTLT*RRQSPCGMAGSPWE TYSLTRCRITLKKSWHLEKKLHQSTLKLKR*MI YPVSCLHLTCIPL*RCLAS*MTLICDGNFYRFL WMIALNSFRKPTEILDHPLSIFSLRQSSCRGKDP FHIIKCPITSTIKHRPPVGTILK*PNSFNPLLT *IMYVFLPTVQQSKSEDYKKHYVWIS*S*VQQM KFSNSTS*TKMTSSSVFQMSSTV*QQLMMDLSKC IRTWSTFHSVLICVSIGCSMSMTRVELEKLECR V*RLD*CLSPKVSWKKNTDISLRKLQGQQKCVT RGSWACYFMMPSRSPGS*VK*QLLEAVILSLVFA AASNRITINQK*V*KSL*IGCIWNHSPWFGSQF YIEWQQRRLQNIRPNATSVKNVQLSGSGIEALS ILTMMSARVVSFRVEQQKVTNYITQWWNIVYLQH LGKMYETSQRYLRTSSGRRSTLPNTLDLVTCLS RQFLKVTT*RLLSHSSVCGQSTMTPHNLLNCFM MTPIQE*NNMPHDWPRWKGLMGLFSLIAAPPQEV WKTSTPSSSSIAKHSEESPQ*ASRRAQLRS*SQ *RGKNVENWRGSLLTWRKNKEIYRWSMSS*RTS TSEGGSLSVHRQSRLYLPITRLRIQNL*QKQNSS GSTKVGWRLGCRF*KITINSWSLSSTASDSCWS SLNLIPESMVFPHGLLLSILH*ATRLIQMPPAH SSTRQRERTCWPHRTTPARISRRSWSRFTARFHL AAQMFPAGHRQCEVFIRPTNVS*RTVLPFSANA NSKFH*IRSSMAPWPTMLSADCVFY*KSKTLTI QREMDILFL**PYIIVFFFPFYASVN**TERYLE MVIHLSRICIMYTALGKWVGAF*YDTVFLITMT KLT*ELEDHFTFLHSFCCSY*PCTITSFFL*LF YHNVLVIYNLSAICLSAI*PTRSQIDPCICFRDL ATLINS*ISIKYLIYTHIWFKLQPCVCRLTLFD VAHLLLC*PLG*P**KSYKPKWHFFWDIFPAFY SLFI*VGINYLFYVLIYLIKKTTL**SQRSYYQR LPT*AYFHFDTETKFSTTFPSSHVLIFIITCTA DLYLL*YQNTSLSLVPFKENFIVVLYFQVLNSS *NS*LFSC*KQTHI*CTAYFTFRVKDQMFLYPSL DQYIWKECLSKVYVTASTEE*N*CLGDGTSTYI FLSAFNYVFWFSF*FNI*LIQFKHVT*LANVEE PKKGENNMF*FKPKDIKT*RHFNFGFSLAGIWPE GGLKLEIAIILE*VGWVGGQGCLFAAEIF*KEE NCFI*KGKP*PPFYLRSIFIHCIGNCFMLLQSA KSRAFIRPCHTQESTYLKKKQFPELSTPSCRFGV FLVLTLKSHVLIFFLPVFVCKMSSICY*RKAT* NTTL*PSK***IKRNILQ*QWEVSM*FF*NMW* RTNHRLSSNLVTYCIFHPE*K*F*HK

Frame 2

GAIAKLPGSGPGETEGTGGGGRPIGV*SRAVAG SPFPDSGDLLLQLTRY*CQAEPS*EVESLRKRT W*SFWIILKLWQDGQVWRT*SQS*QWAERIQ*Y H*VQI**TQ*RTEENLYQMDKCSIFKEWETTHQ* YVHRPQRWKEAIGSSRRPHRNITAKGTWFHKGT CLK*RQQSAAGFTSEQCGISEYRGN*HCGWKSQ TDFGVTLEHHFALAGERCHEGCHVGPAADEQ*ED PAQLGASDHQALQPSQRPQLHHQLDRWTRL*CC PPPT*T*SLQLG*SCQNVTN*ET*TCLQQGSNL FGN*KAVRS*RCCRSAS*QEIHNYVFNIFV*GAT SASHHRRHP*GRDTPKEI*KRM*RRGN*YTEYS A*GGA*ESPS*NSQHCH*G*HGSGQLSDCVGGS ADLVAFC*GHFPGAG*YF**C*RSQRPVCNP*SF YDGTDCTPEQCGQRPAGRQPTDNTRNSVRRRRI *DSGTDDPAEC*MGGS*GGEYGQTVPAARCADG TAEEATAAALRLVNTHRGAHSEDGNLPPG**CKI STKAARRT*KFAK*S*G*TGESKFTNSHGGHC* *KQW*ECYSYPRRPVTETW*ALDSSMPLD*RTL E*VTRNQYIVAGIIGRTVLVESLVNRKRRGFK*S PDKQLQRPKGTKCQCSTSGYFEGRHGNEASNIG SAE*DWPGCGTIT**FQGI*EDQQ*LRGTDSKM GFFGSETRRFLQPGDSGCSKAGDVSDSSEGPFGD CSCKRTSNYKKI*AGTASSSSPKEETDPCGY*S *EKV*CYKCRAVELDFEMENCHSDHRDKRVYED ARHFRNEKEVEGIRKRTERKNPQSR*IKPNWTNP CGANGKRRPSY*RNKKCSGEGFIRMEECISTFG RSRKKDSATGRYKCLFQAA**A*KGHQDKGGVG KTHFHF*IFPAVLAKLEGFLSAGIDKSSWPSPQN *NGSCKLLGPDVSAFCPRFCPAGLR*LSGPLPS CTRGCRGSSTTSRE*TEGPTWTCISGNIENTER CAK*FRK*GPGVSECP**SCQGGEGPARKKDP** NP*ESETCIT*TCRRNKGSGEKCSS*CRKII*A RI**CARKVEQAKGLGFQRSTFA*GNCSHTQSF *GRFNSH*EVDGWRERLLNETAGCPRRRRRSTEA VRPVLCIC**NRNN*IISEKHEGNRD*SSKWSS CWNKNLGADKTR*LPNSTGET*QGDRYSKK*VV *KSRKSCEPEERLGRDAGMDDPGRGRIFGAGF*V QVTRRA*ECCGRDEEGKRGCVAEGGESEDSQGQ HQVISCQGALWWPGVDV*AECCAGELPTSL**N SRKVPHARGGLVLLD*TASLFGS*NYLVKHFGRA DEEHRGPA*EDGCCQRSPGVSGICSAPPGR*SH PDSRAWPDSD*WGDPG*YNQ*ETGGFQQPI*RS KSPGREQADFFGKATPGAAGN*PDASSLARELGG AGQTAHHIPD*QDRCFPSSTGSSENPSRDLSP* ANPRGVEKKYAFSAPDLPRE*DCQRRKSDGCAT EETPRGVHKVPAFPEAS*LRAAHAGLQACAGWRE SRTSRSGCEGRRP*RHTDAPGQVYETV*NFE*S QT*SGNCD*NRKTYCPETANGQPKRDG*AADFP EGSLQ*PGRTGDRRKTGSGKSITVGPENEERGCF SL*MAFCY*N*IGTEVHFRRSAW*LGYRNFLG* KCSEGSGKEKS*FKYHHRE*CCPAKLD*GQ*AY FRREALRP*RWVEPSSYLD*RLVQYLDEPSEPAR NI*WERGSHKYLALSS*SSIG*N*KETNK*TGR NCEAFSI*AG*CQPPG*KCPRSSPYFDECPWKL KQGACRTKVS*AE*EL*KGVSTYQKCQIANCSGT IIPMFGHH*NI*NWCAFL*LGKIRK*HRKYVKI CGKTLGIQ**R*KDG*GECPD*GSSTKRRRNVT STYGR**KRKDPFAIITFAY*IQQN*GNPYSTEE NGSTCFWN*IITSSYRLSG*N*QNFTLHG*C*I IA*CSRAQHCYLRRLLFSGRLSEEYQRPTGQTW RADCSHS*KTARCHP*SLWT*SHSDQRYTYSAEC KMGQN**NVQ*SERLF*QGNGRMETVPL*P**P HTVDNRG*RITG*YLCSRWQPGLRESQDTSAGT *GGHQQPPAQFCSTKPNWGWDCAETLPGRWKLLE RKTGRFKPTLGCNCCRSEG*AAKAKRRK*AGDE VQASAR*DYLLVNKG*ACYAKEINHRIGRKPAR IKRLNSRNGSTC*KTQMAE*N*IGDAFR*KSEFT *KG*NFRKLKDCKYDME*DLQRGAYHPEGMHPG AQFCFTDKDCCSS*CPKGGASIICVRYSCSVSS YFGNFNSC*S**NYNRTSRLAGINRPDAEVQHCH CWGCRRDQ*DRFPNENYKG*LRTAPSSAGLCFY IGTEFEK*SFQFRYENSNYRKIGKGQEPVGWHP AWR*AKTAAA*GHDY*QSSVG*P*GGD*RTDEKI *GSTLYSSASPTGSTHQTNF**PNTASRTGSWR WYRHGVR*RPAETPGGIWE**HKECERNHRVLK NIMDQSQTKYC*QTERLGG*VEDGAGLSQRSGKL PEVDPRSRDHSECACGCLSSGECSSG*YLGQGT QTADAGHPGRN*CPQ*HI*KH*RKQAEDGKSFG KF*RGYYASTSTG*YEPKME*LKSKIC*HQGPFG GQR*EVEQVADVLRRTDQMAEYER*RA*ETNAY WRRCSSLTAPV*PL*GPETGVKGERIFCPECCR PGPSFLG*SAN*GP*RAKKKPTIKNRINS*GESP KDCQSHAQTVF*SQRKMGKSKCCN*QLAKASGQ GIGETQRPAGSYG*PGR*HEGGRVRAEWLEARG RLTH*LAAGSH*KNHGI*RRNCTNQL*S*NGE*F IQSAVST*PASLSKDVSPAR*P*YAMETFTGFC G*SP*TASGSPQRFWTILSAFSLYVSPAAVAKI HFT**SALLHQPSNTDHLLGPS*NDRTLSIPC*P E*CTFFCLPYSNQNPKTTKSTMFGSLRVEYNK* NFQTAQVEPK*PAPQCSRCHQLSDNNL*WT*AN A*GPGQRSTLC*YVSQLVAQCL*HGSNWKN*SAE SEDWINVSLQRSLGRKIQISL*GSCRANRNV*P EAAGPVTS*CHPDPPAAR*SSSFWRQ*Y*A*CS QLLPTE*Q*TRNKCERVYRLDAFGTTVHGLAPSF TSSGSSGDCKTSGQMQHL*RMSNCRVQV*KP*A F*L*CLPELFLFGSNSKRSQITLPNGGILYTYN IWGRCTRLHKGT*EQVQVEEVLCQTPSTWLPACP DSS*R*QLRDSYHTHQYVARAL*PLTISSTVS* *HPFKNRTICHTTGPDGKD*WVFSH**QLHHRK CGRRARPHPAVLPNTRRRVPSEPAAEPSSDPEVS REGRTWRTGEDHC*PGGRTKKSTGGV*AAEGPA PPKGAPCRFTARVDYISPSHV*GFRTYSRSKTP QAAQRSAGG*DADFRRSQ*TAGVSAPPPPTAAGA A*I*FPNQWCFPMGFSSAFCTELLA*SRCLRPT VPPGSGRGPAGPTARHQHGSHGGHGADSQHVSI LLPKCSQQATGNVKYSSGQPMFPDVQCCPFQQMP IPSSIKSEAPWLLGPRC*VLTVCSTERVKH*LS KEKWIFCFYNNHILLFSSSLSMQV*INEQRGIW KW*YICHGFV*CIQHWESGWGLSNMIPSF**L*Q SLHKN*KTTLHFYIPSAVHINLAQLLHFFFDSF TTMFWLFIIYQPYVYQPYNQLDPK*IHVFVSVI WPH**IHKFQSNILYIHTYGLSYSPVYAV*LYLT LPTYFFADHLDNRNKNPISLNGISFGIFFLHFI PFLYK*ELIIYFMS*SI**RRLHYNNLKDHITK GCPLEHIFILTQKQNLVQPFLVPMS*FSSLHAQQ TFTYCDTRTHHCLWFPSKRILLLFCIFKSLIVL ETPSCFLVESRHTFSARLILPFG*KIRCFYTLH LINIFGKNVYQKSMSLLLQKNEINA*VMVPPPTS F*VHSIMYFGLASDLTFN*FSLNMLLN*QM*RN QKKVKIICFDSNLKT*KHKDILTLGSL*LGSGQ KEA*S*KLLLF*NRLGGLGGKGVYLQQRYFEKKK IVLYKKESHDHLSTSDPSSSIALETALCCCSLQ SLELLSGHVIPKKAPI*RKNNSLSSQLQVVDLV SSLFLL*KVMC*FFFCLYLYAKCPLSAIKEKLRK TLHCNLLSNNK*KEIYCSNNGK*VCSSFEICGK ELITDYHLIWLHIVFFILNKSNFNTR