Sequences - Rnomics 📊 Palace

        ☰
    
        Rnomics 📊 Palace
    
                       Back to Rnomics Platform
            
                       Open Session

1 warning:

Access restricted to public data.
Please sign in at Rnomics Platform to access your data.

Navigation

Home

Sequences

Sequence ACACA.cAug05

GCCGTGGAGGCCCCCGCCGGGTGCTGAGCGCCCGCCACCGCCCTCTTGGCCTTTTCCCGGTCCCCGCCGCGCGCCTGCTGCTGTCCCCGTGCCCGAGGAC TGGGAGGATGGGGCTGAGCCGCTTGCCTGACTTTTGATCCGACCAGTAATCACTTTGCCCGTGTGGCGCGTGGCCCGTTGCCTGAGGCTTCCTGGCGCGT GGGGCTGTTTGGTCCCCTCCGGAGTGCGGTGAGGCGGGCCGAGCCGGGACTGCCTGGGTTTGGGGATAACGTTCCCATCTCCACCCCTGTTGCAGCAAGG GAAATTGAGGCTGAGGGAACTGGGCCCAGGGACGGCGAGCCGTGGCTGCCTCTCCAGTCCGGGCCCCGAAGGGCTGCTCGTGGATGAACCAGACTGATTT TAAGGGGTGAAGAGGGTGCGTTTCAATCAGATGCTTCTGGAACGTCGAAATTGTCTTCTTTGGAAAGAACCATCCCCTCTTTGGGCTTCAGAGGCCCAAA TTGAGGCGCAATGATGAGAGGATGTGGTGGTCTACTCTGATGTCAATCTTGAGGGCTAGAGTCTCGCTCTGTCACCCAGGCCTGGGTTCACACCATTCTC CTGCCTCAGCCTCCCAAGTAGCTGGGACTACAGGCTGGAGTGCAATGGCATGATCTTGGCTCACTGCAACCTCCGCCTCCCGGATTCAACGGATTCTCCT GCCTCAGCCTCCTGAGTAGCTGGGATTATAGGTGCCTGCCACAACACCCAGGACCAGACTTATGAAGTGGCCTTCCTGAGGAGATTTTCTGACCTTATGG TATGAAGTTCCTTCAGGCTCTTAATTCTGGATAAACTGGAGTGATTAACAAGAGCAAAGAGACATAGTATTCAGATAAGGACTTTGTGTCTTATTTTTCT TTTATATCACAACTGGAGCCACAGTTGTGGGCAAGGCACTGACTTTCTTGATGAATTCTGTCCATCTGTAAAGCAGCTATATATCCCACTGGAGGCTTTG CCTCTCAGAGACAACGTGAAGACGGATAAGCAGGCATCAGGAGCAGAGTGGCCTCTCAGCTGGTCAGATTCTCCGAAGAAGGATCCTCTAGGCTGGGCAC GGTGGCTCACACCTATAATCCCAGCACTTTGGGAGGCCGAGGCAGGTGGATCACGAGGTCAGGAGTTCGAGGCCAGCCTGGCCAATATGTCTCAGTAAGT AGTCTTTCTAGGCAGGATTTTTCTTCCCTGCTTAAGGGGGTTAGACCTCCAAAATATTTGTCAGGGTCTCTTTTCCTTTTAAGGGTTTAACCCACAATCT TTTCTGTATCCGTTTTGTACCAGCTCCATTCCTATTCTCAAGCTTTGGTGCATAAAACCTTAGTTTAGGTGTCTATATATACCACTACTTTGGCCTGAAA ATTAGAATCGTGGCTCACACTTGATTCTAAGTTCCCTAGTAGTGGCGTGTTTCCTTTCTACGTGCTTACTTTCCCACCTGACCTGCTTTTCCCCACCGTG CAGTCTGATAATTGGTATTATTTGTTTTGATTGGATCTCAGAAATTACCTCTTTAGACCGAGCTGTGCTCCTCCCTCTGGATTTCATGAGCCCATTATTT TCTTGGCTTAATTGTCCTTGTAAATTTGGTCTTTTTGTCCTGGGCTTTCCCTGTCATGTGCTCCTGGCAGCCAGGAGAGGCAGTGGAGCTTTTCTCCGTT GACTGTCAGAAGAAAGTGACTGTTGTTGAAAATGTTTGCTGCAACTAAAGGAGAGCTGCTAAGATCTACTTTCTAGTTAAACAAGCTTTTATATTTCTCC CCGGCTCCTCTCAGTTCCCTTGGGAAATCAACTAATTGTGTGTGTAAGCTAAGTGTGTGGAGGAGAGAAGATGCAAAAAGGAAGAGAAAGGTGGGGAAAG AAGGAAATTGGGAACAATTAGACAAAAAGACTATAGTTTGAGGCCATCAGGAGTATTCTAGTCTGACTGAAGCCAGGCAGAAGGCACAGTATCTCTTGTC CTCCTGGGTTTTAAGCAGCTGCAACAGGAGGAGGAACTGCGGCTTGTGTTTACAAGGCCGAAATCTGAAGAAAAAGCTTCCATTCTTTTCCCATCTTGAT ATGGAGGGTTCTCCAGAGGAAAATAAGGAAATGAGATATTACATGCTTCAAAGGTCCAGCATGTCTGGCTTGCACCTAGTAAAGCAGGGCCGAGACAGAA AGAAAATAGATTCTCAACGAGATTTCACTGTGGCTTCTCCAGCAGAATTTGTTACTCGCTTTGGGGGAAATAAAGTGATTGAGAAGGTTCTTATTGCTAA CAATGGCATTGCAGCAGTGAAATGCATGCGGTCTATCCGTAGGTGGTCTTATGAAATGTTTCGAAATGAACGTGCAATTAGATTCGTTGTCATGGTCACA CCTGAAGACCTTAAAGCCAATGCAGAATACATTAAGATGGCAGATCACTATGTGCCAGTGCCTGGAGGACCAAACAACAACAACTATGCAAATGTGGAAT TAATTCTTGATATTGCTAAAAGGATCCCAGTACAAGCAGTGTGGGCTGGCTGGGGTCATGCTTCTGAGAATCCCAAACTACCGGAACTTCTCTTGAAAAA TGGCATTGCCTTCATGGGTCCTCCAAGCCAGGCCATGTGGGCTTTAGGGGATAAGATTGCATCTTCCATAGTGGCTCAAACTGCAGGTATCCCAACTCTT CCCTGGAGCGGCAGTGGTCTTCGTGTGGACTGGCAGGAAAATGATTTTTCAAAACGTATCTTAAATGTTCCCCAGGAGCTATATGAAAAAGGTTATGTGA AAGATGTGGATGATGGGCTACAGGCAGCTGAGGAAGTTGGATATCCAGTAATGATCAAGGCCTCAGAGGGAGGAGGAGGGAAGGGAATTAGAAAAGTCAA CAATGCAGATGACTTCCCTAATCTCTTCAGACAGGTTCAAGCTGAAGTTCCTGGATCTCCCATATTTGTGATGAGACTAGCCAAACAATCTCGTCATCTG GAGGTGCAGATCTTAGCGGACCAATATGGCAATGCTATCTCTTTGTTTGGTCGTGATTGCTCTGTACAACGCAGGCATCAGAAGATTATTGAAGAAGCAC CTGCTACTATTGCTACTCCAGCAGTATTTGAACACATGGAACAGTGTGCGGTGAAACTTGCCAAAATGGTGGGTTATGTGAGTGCTGGGACTGTGGAATA CCTGTACAGCCAGGATGGCAGCTTCTACTTTCTGGAATTGAATCCTCGGCTGCAGGTAGAGCACCCTTGTACAGAGATGGTGGCTGATGTCAATCTCCCT GCAGCACAGCTCCAGATTGCCATGGGGATTCCTCTATATAGAATCAAGGATATCCGTATGATGTATGGGGTATCTCCCTGGGGTGATTCTCCCATTGATT TTGAAGATTCTGCACACGTTCCTTGTCCAAGGGGCCATGTTATTGCTGCTCGGATCACTAGTGAAAATCCAGATGAGGGTTTTAAGCCCAGCTCAGGAAC AGTTCAGGAGCTAAATTTCCGCAGCAATAAGAATGTTTGGGGATATTTCAGTGTTGCTGCTGCAGGGGGACTTCATGAATTTGCTGATTCTCAGTTTGGT CACTGCTTTTCTTGGGGAGAAAACAGAGAAGAGGCAATTTCAAACATGGTGGTGGCTTTGAAGGAGCTGTCTATTCGGGGTGACTTTCGAACTACAGTTG AATACCTGATCAAATTGTTAGAGACTGAAAGCTTTCAGATGAACAGAATTGATACTGGCTGGCTGGACAGACTGATAGCAGAAAAAGTACAGGCTGAGCG ACCTGACACCATGTTGGGGGTTGTGTGTGGTGCCCTCCACGTGGCAGATGTGAGCCTGCGGAATAGCGTCTCTAACTTCCTTCACTCCTTAGAAAGGGGT CAAGTCCTTCCTGCTCATACACTTCTGAATACAGTAGATGTTGAACTTATCTATGAGGGAGTCAAGTATGTACTTAAGGTGACTCGACAGTCCCCCAACT CCTATGTGGTGATCATGAATGGCTCATGTGTAGAAGTAGATGTACATCGGCTGAGTGACGGTGGACTGCTCTTGTCCTATGATGGCAGCAGTTATACTAC GTATATGAAAGAGGAAGTGGATAGATATCGCATCACAATTGGCAATAAAACCTGTGTGTTTGAGAAGGAAAATGACCCATCGGTGATGCGCTCACCTTCT GCTGGGAAGTTAATCCAGTACATTGTAGAAGATGGAGGTCATGTGTTTGCCGGCCAGTGCTATGCTGAGATTGAGGTAATGAAGATGGTAATGACCTTAA CAGCTGTGGAGTCTGGCTGTATCCATTACGTCAAGCGACCTGGAGCAGCTCTTGACCCTGGCTGTGTACTAGCCAAAATGCAACTGGACAACCCCAGCAA GGTTCAGCAGGCTGAACTTCACACAGGTAGTCTGCCACGGATCCAGAGCACGGCACTCAGAGGCGAGAAACTCCATCGAGTGTTCCATTATGTCCTGGAT AATCTGGTCAATGTAATGAATGGATACTGCCTTCCAGATCCTTTCTTTAGCAGCAAGGTAAAAGACTGGGTAGAGCGATTGATGAAAACCCTCAGAGATC CCTCCCTGCCTCTCCTAGAATTGCAAGATATTATGACCAGTGTGTCTGGCCGCATTCCCCCCAATGTGGAGAAGTCTATCAAGAAGGAAATGGCTCAGTA TGCTAGCAACATCACATCAGTCCTCTGTCAGTTTCCCAGCCAGCAGATTGCAAACATCCTAGATAGCCATGCAGCTACATTGAACCGGAAATCTGAACGG GAAGTCTTCTTTATGAATACTCAGAGCATTGTTCAGCTGGTACAGAGGTACCGAAGTGGCATCCGAGGCCACATGAAGGCTGTGGTGATGGATCTGCTCC GGCAGTACCTGCGAGTAGAGACACAATTCCAGAATGGTCACTATGACAAATGTGTATTCGCCCTCCGAGAAGAGAATAAAAGTGACATGAACACTGTACT GAACTACATCTTCTCTCACGCTCAAGTCACCAAGAAGAATCTTCTGGTCACAATGCTTATTGATCAGTTGTGTGGCCGGGACCCTACTCTCACTGATGAG CTGCTGAATATTCTCACAGAGCTAACTCAACTCAGTAAGACCACCAATGCCAAAGTAGCACTTCGAGCACGCCAGGTTCTTATTGCCTCCCATTTGCCAT CATATGAGCTTCGCCATAACCAAGTAGAGTCTATCTTCCTATCAGCTATTGACATGTATGGACATCAATTTTGCATTGAGAACCTGCAGAAACTCATCCT ATCAGAAACATCTATTTTTGATGTCCTACCAAACTTCTTCTATCACAGCAACCAAGTAGTGAGGATGGCAGCTCTGGAGGTGTATGTTCGAAGGGCTTAT ATTGCCTATGAACTTAACAGCGTACAACACCGCCAGCTTAAGGACAACACCTGTGTGGTGGAATTCCAGTTCATGCTGCCCACATCTCATCCAAACAGAG GGAACATCCCTACGCTAAACAGAATGTCCTTCTCCTCCAACCTCAACCACTATGGCATGACCCATGTAGCTAGTGTCAGCGATGTACTGTTGGACAACTC ATTCACTCCACCTTGTCAGCGGATGGGCGGAATGGTCTCTTTTCGGACTTTTGAAGATTTTGTCAGGATCTTTGATGAAGTGATGGGCTGCTTCTCTGAC TCCCCACCCCAGAGTCCCACATTCCCTGAGGCAGGTCACACGTCTCTTTATGATGAGGATAAGGTTCCCAGGGATGAACCAATTCACATTCTCAATGTGG CTATCAAGACTGACTGTGATATTGAGGATGACAGGCTGGCAGCTATGTTCAGAGAATTTACCCAGCAAAATAAAGCTACCCTGGTTGACCATGGGATCCG GCGCCTTACTTTCCTGGTTGCACAAAAGGATTTCAGAAAGCAGGTCAACTATGAGGTGGATCGGAGATTTCATAGAGAATTCCCTAAATTTTTTACATTC CGAGCAAGGGATAAGTTTGAGGAGGATCGTATCTATCGTCATCTGGAGCCTGCTCTGGCTTTCCAGTTAGAGCTGAACCGGATGAGAAATTTTGACCTCA CTGCCATTCCATGTGCTAATCACAAGATGCACCTGTATCTCGGGGCAGCCAAGGTGGAAGTGGGCACAGAAGTGACAGACTACAGGTTCTTTGTTCGTGC AATCATCAGGCATTCTGATCTGGTCACCAAGGAAGCTTCTTTTGAATATCTGCAAAATGAAGGGGAGCGGCTACTCCTGGAAGCCATGGATGAGTTGGAA GTTGCTTTTAACAATACAAATGTCCGCACTGACTGTAACCACATCTTCCTCAACTTTGTGCCCACGGTTATCATGGACCCATCAAAGATTGAGGAATCCG TGCGGAGCATGGTAATGCGGTATGGAAGTCGCCTGTGGAAATTGCGCGTCCTCCAGGCAGAACTGAAAATCAACATTCGCCTGACGCCAACTGGAAAAGC AATTCCCATCCGCCTCTTCCTGACAAACGAGTCTGGCTATTACTTGGATATCAGCCTATACAAGGAAGTGACTGACTCCAGGACAGCACAGATCATGTTT CAGGCATATGGAGACAAACAGGGACCACTGCATGGAATGTTAATCAATACTCCATATGTGACCAAAGACCTGCTGCAATCAAAGAGGTTCCAGGCACAAT CCTTAGGGACAACATACATATATGATATCCCAGAGATGTTTCGGCAGTCCCTGATCAAACTCTGGGAGTCTATGTCCACTCAAGCATTTCTTCCATCTCC CCCTCTGCCTTCTGACATGCTGACTTACACTGAACTGGTACTGGATGATCAAGGTCAGCTGGTCCACATGAACAGGCTTCCAGGAGGAAATGAGATTGGC ATGGTAGCTTGGAAAATGACCTTTAAAAGTCCTGAATATCCAGAAGGCCGAGATATCATTGTTATTGGCAATGACATCACATACCGAATTGGGTCCTTTG GGCCTCAAGAGGATTTGTTATTTCTCAGAGCTTCCGAACTTGCTAGGGCAGAAGGTATTCCACGCATCTATGTATCAGCCAACAGTGGAGCAAGAATCGG ACTGGCAGAAGAAATTCGCCATATGTTTCATGTGGCCTGGGTAGATCCTGAGGATCCTTACAAGGGATACAGGTATTTATATCTGACTCCTCAAGATTAT AAGAGAGTCAGTGCTCTCAACTCTGTCCATTGTGAACACGTGGAAGATGAAGGAGAATCCAGGTACAAGATAACAGATATTATTGGGAAAGAAGAGGGAA TTGGACCCGAGAACCTTCGAGGTTCTGGAATGATTGCTGGAGAATCCTCATTGGCCTATAATGAGATCATTACCATCAGCCTGGTGACGTGCCGGGCCAT TGGGATTGGGGCTTACCTTGTCCGGCTGGGACAGAGAACCATCCAGGTTGAGAATTCTCACTTAATTCTAACAGGAGCTGGAGCCCTCAACAAAGTCCTC GGGCGGGAAGTGTACACCTCCAATAACCAGCTGGGGGGCATCCAGATTATGCACAACAATGGGGTGACCCACTGCACTGTGTGTGATGACTTTGAAGGGG TTTTCACTGTCCTGCACTGGCTGTCTTACATGCCCAAGAGCGTGCACAGTTCAGTTCCTCTTCTGAACTCAAAGGATCCTATAGACAGAATCATCGAGTT TGTTCCCACAAAGACCCCATACGATCCTCGATGGATGCTAGCAGGCCGTCCTCACCCAACCCAAAAAGGTCAGTGGTTGAGTGGCTTTTTTGACTATGGA TCTTTCTCAGAGATTATGCAGCCCTGGGCACAGACTGTGGTGGTTGGTAGAGCCAGGCTAGGAGGAATACCTGTGGGAGTTGTTGCTGTAGAAACCCGAA CAGTAGAACTAAGTATCCCAGCTGATCCAGCAAACCTGGATTCTGAAGCCAAGATAATCCAGCAGGCTGGCCAGGTTTGGTTCCCAGATTCTGCGTTTAA GACATATCAGGCCATCAAGGACTTCAACCGGGAAGGGCTGCCTCTGATGGTCTTTGCCAACTGGAGAGGCTTCTCTGGTGGAATGAAAGATATGTACGAC CAAGTGCTGAAGTTTGGTGCTTACATTGTGGATGGCTTGAGGGAGTGCTGCCAGCCTGTGCTGGTTTACATTCCTCCCCAGGCTGAGCTGCGGGGTGGCT CCTGGGTGGTGATTGACTCCTCCATCAACCCCCGGCACATGGAGATGTATGCTGACCGAGAAAGCAGGGGATCTGTTCTGGAGCCAGAAGGGACAGTAGA AATCAAATTCCGCAGAAAGGATCTGGTGAAAACCATGCGTCGGGTGGACCCAGTCTACATCCACTTGGCTGAGCGATTGGGGACCCCAGAGCTAAGCACA GCTGAGCGGAAGGAGTTGGAGAACAAGTTGAAGGAGCGGGAGGAATTCCTAATTCCCATTTACCATCAGGTAGCCGTGCAGTTTGCTGACTTGCACGACA CACCAGGCCGGATGCAGGAGAAGGGTGTTATTAGCGATATCCTGGATTGGAAAACATCCCGTACCTTCTTCTACTGGCGGCTGAGGCGTCTTCTGCTGGA GGACCTGGTCAAGAAGAAAATCCACAATGCCAACCCTGAGCTGACTGATGGCCAGATTCAAGCCATGTTAAGGCGCTGGTTTGTGGAAGTGGAAGGAACA GTGAAGGCTTATGTTTGGGACAATAATAAGGATCTGGCGGAGTGGCTAGAGAAACAGCTGACAGAGGAGGATGGTGTTCACTCGGTAATAGAGGAAAACA TCAAATGCATCAGCAGAGACTACGTCCTCAAGCAAATCCGCAGCTTGGTCCAGGCCAATCCAGAGGTTGCCATGGATTCCATCATCCATATGACGCAGCA CATATCACCCACTCAGCGAGCAGAAGTCATACGGATCCTCTCCACAATGGATTCCCCTTCCACGTAGGAAGAGCTTCCTGCCTGTCCCTGCCCTGTCTCT GGAGAAAAGGGCTAGAGCTGCCTTTTACAACTGTAACCACTGTAATGAGAAGGCACAGGAGACCCAGCACTGGAGTCAAATGGCATTTTACTTCCTCTCG TTTCAGGTTATGCATGACATCCTGGGATGTAAGATCACAGAATCCCCCTCCAGCCCACCAGTCACACCTACCCCATTCAGTATTTATTACCCTGGCCAGG CCTAGTCCTCCACTCCCTGCACAGGACTGAGAAGGCAATGAAAGGTACAAACATGTACCATGAGGTCTTACTAACCAAAGTAGGGCTGCCCCTCCTGTCC TGACAGCCCCTTGGCCTCCCAGCATGGGGAAGCGTGAGGAGTTGCCCAGCAGTGAGCAGCCCCCCTCACTCCTGGCCCCATGAGCCGCAGCCACAGGCAG CAGAGGAGGGCTAAGGAGAGGAGGAAGCCTCAAGTCCATTGTTTATTACCCCGACTCTTAGCCCAGCACACAGTAGGCACTGGAGAGGAATGATTCCCAG TTTAACCACACTACGGTACCTTTTATGAAGAAAAATTAGAGCATAAAATCTACTACAAGCTCCATAGGAACTCAAAGATGAGGGCAAAACTGTGAGCCAA GAAGCAGAGAAAGAAAATAGAACCAGTTATTCTTGATTTAGGGGACCTCAACCTTGGGTTCAGTCTCTGAGGACAAAGGGAAAGGTAGTTGTTGGCCTGC CTCTCGCCTGCACGTCACTGCTGGACTAGCTGTCGCATGTGGCTGGGAGCTGCAAGGCCAGTGCTTGAGGGGCCCCAGCAGTTCCACAGGTGGTGAAGCC TGAGTTGGCAGAGGAGGAGCCAGAAGAGAACTGCCCTTTCTGCACTGGTGGAAACTAGTTATTTATGCCATGTGGAGAGCCAGTGAGATAGATAGATAGT CTGTTTGTTTTGAGGACTTGGAAAGTTGTTCCTATGAAGCCTGGAGCTTGGATGGTTTTGAGAGGTTAATGGTGCCTCCACACTCACTCTTCCCTAGTTC CAGGATTACTGTCCTAGCAGCTAACGGTTCTACTCTCTTCCCCAGAGTGTAGACAGGCAGCAGGTCTCCCCACAGCTCTGAAAGGACCCTGGTGACAGCT ACACCCTCAGCACCAGGAGCTGGCCTTCCTGATGAGGGAGGCTTCCAGGAAACACAGAATCCACATGACCTTAAGATTATTTACAACTCAGTCATGGTGC TGCTGTCCTCCAGGCTTACTGGCCCCTCCTGACTGGCATCAGGGGCTTCCTCAGGTGGTGGAGAGAGTTTACTTTCAACAACTAGTTTATTCAAGAAAAG AACTTACTGATTCCTCTGTTCCTAAAGCAAGAGTGGCAGGTGATCAGGGCTGGTGTAGCATCCGGTTCCTTTAGTGCAGCTAACTGCATTTGTCACTGAT GACCAAGGAGGAAATCACTAAGACATTTGAGAAGCAGTGGTATGAACGTTCTTGGACAAGCCACAGTTCTGAGCCTTAACCCTGTAGTTTGCACACAAGA ACGAGCTCCACCTCCCCTTCTTCAGGAGGAATCTGTGCGGATAGATTGGCTGGACTTTTCAATGGTTCTGGGTTGCAGGTGGGCACTGTATGGCTGGGTA TGGAGCGGACAGCCCCCAGGAGTCAGAGCCTCAGCCCGGCTGCCCTGGTGGAAGGTACAGGTGTTCAGCACCTTCAGAAAAGGGCATAAAGTGGTGGGGG ACAATTCTCAGTCCAGGAAAATGCATTGACCATTGCTGGCTATTTGCTTACCTAGTAAGAATTGGATTCATTTTTGACCAGATTATTCTTCTATGCTTTT TTGCAATAAATCAAATCCCACATATCTACAAGTGGTATGAAGTCCTGCACCCCCCAGGAGGCCTGTCCAGGCATGTCTTCAGAGGCAGGGTGGGTTACAC TCATTTACCTCCCCTCTCCCCACCAAATTATGACACAAACGAGTATGTTTCCTCTCTAGAACCCTGTAATGCCTCCTCCCCCATCCCCAGAGCTCCTTAC TGTAGGTCTTACCCTGGACAAGGATTTTTTCAAGTTGGAGGCACAGAACATGAGCAATCTGACATTCCCACAGCCCCTCAAACATGCAAGGCTACTAAGG CAGGAGGAGTATAAATGATGGATATTGACCAAGACCTGCTTGGACGGAGACCGCCATATTATCTGTTCTCTTCGTTCACAAAACAGCCTTCACTTGTCTC AGAATTTGATGGACACATACTGTGATGAGCAGGAGCTTCAGATGCACTCTTTACACATTTTGTTGAAATAAACCTCTACATTTGTAGAAGAGTT

ACACA.F5 (forward primer)
ACACA.R5 (reverse primer)
Mutually exclusive exon skipping

Frame 0

AVEAPAGC*APATALLAFSRSPPRACCCPRARG LGGWG*AACLTFDPTSNHFARVARGPLPEASWRV GLFGPLRSAVRRAEPGLPGFGDNVPISTPVAAR EIEAEGTGPRDGEPWLPLQSGPRRAARG*TRLI LRGEEGAFQSDASGTSKLSSLERTIPSLGFRGPN *GAMMRGCGGLL*CQS*GLESRSVTQAWVHTIL LPQPPK*LGLQAGVQWHDLGSLQPPPPGFNGFS CLSLLSSWDYRCLPQHPGPDL*SGLPEEIF*PYG MKFLQALNSG*TGVINKSKET*YSDKDFVSYFS FISQLEPQLWARH*LS**ILSICKAAIYPTGGF ASQRQREDG*AGIRSRVASQLVRFSEEGSSRLGT VAHTYNPSTLGGRGRWITRSGVRGQPGQYVSVS SLSRQDFSSLLKGVRPPKYLSGSLFLLRV*PTI FSVSVLYQLHSYSQALVHKTLV*VSIYTTTLA*K LESWLTLDSKFPSSGVFPFYVLTFPPDLLFPTV QSDNWYYLF*LDLRNYLFRPSCAPPSGFHEPII FLA*LSL*IWSFCPGLSLSCAPGSQERQWSFSPL TVRRK*LLLKMFAATKGELLRSTF*LNKLLYFS PAPLSSLGKSTNCVCKLSVWRREDAKRKRKVGK EGNWEQLDKKTIV*GHQEYSSLTEARQKAQYLLS SWVLSSCNRRRNCGLCLQGRNLKKKLPFFSHLD MEGSPEENKEMRYYMLQRSSMSGLHLVKQGRDR KKIDSQRDFTVASPAEFVTRFGGNKVIEKVLIAN NGIAAVKCMRSIRRWSYEMFRNERAIRFVVMVT PEDLKANAEYIKMADHYVPVPGGPNNNNYANVE LILDIAKRIPVQAVWAGWGHASENPKLPELLLKN GIAFMGPPSQAMWALGDKIASSIVAQTAGIPTL PWSGSGLRVDWQENDFSKRILNVPQELYEKGYV KDVDDGLQAAEEVGYPVMIKASEGGGGKGIRKVN NADDFPNLFRQVQAEVPGSPIFVMRLAKQSRHL EVQILADQYGNAISLFGRDCSVQRRHQKIIEEA PATIATPAVFEHMEQCAVKLAKMVGYVSAGTVEY LYSQDGSFYFLELNPRLQVEHPCTEMVADVNLP AAQLQIAMGIPLYRIKDIRMMYGVSPWGDSPID FEDSAHVPCPRGHVIAARITSENPDEGFKPSSGT VQELNFRSNKNVWGYFSVAAAGGLHEFADSQFG HCFSWGENREEAISNMVVALKELSIRGDFRTTV EYLIKLLETESFQMNRIDTGWLDRLIAEKVQAER PDTMLGVVCGALHVADVSLRNSVSNFLHSLERG QVLPAHTLLNTVDVELIYEGVKYVLKVTRQSPN SYVVIMNGSCVEVDVHRLSDGGLLLSYDGSSYTT YMKEEVDRYRITIGNKTCVFEKENDPSVMRSPS AGKLIQYIVEDGGHVFAGQCYAEIEVMKMVMTL TAVESGCIHYVKRPGAALDPGCVLAKMQLDNPSK VQQAELHTGSLPRIQSTALRGEKLHRVFHYVLD NLVNVMNGYCLPDPFFSSKVKDWVERLMKTLRD PSLPLLELQDIMTSVSGRIPPNVEKSIKKEMAQY ASNITSVLCQFPSQQIANILDSHAATLNRKSER EVFFMNTQSIVQLVQRYRSGIRGHMKAVVMDLL RQYLRVETQFQNGHYDKCVFALREENKSDMNTVL NYIFSHAQVTKKNLLVTMLIDQLCGRDPTLTDE LLNILTELTQLSKTTNAKVALRARQVLIASHLP SYELRHNQVESIFLSAIDMYGHQFCIENLQKLIL SETSIFDVLPNFFYHSNQVVRMAALEVYVRRAY IAYELNSVQHRQLKDNTCVVEFQFMLPTSHPNR GNIPTLNRMSFSSNLNHYGMTHVASVSDVLLDNS FTPPCQRMGGMVSFRTFEDFVRIFDEVMGCFSD SPPQSPTFPEAGHTSLYDEDKVPRDEPIHILNV AIKTDCDIEDDRLAAMFREFTQQNKATLVDHGIR RLTFLVAQKDFRKQVNYEVDRRFHREFPKFFTF RARDKFEEDRIYRHLEPALAFQLELNRMRNFDL TAIPCANHKMHLYLGAAKVEVGTEVTDYRFFVRA IIRHSDLVTKEASFEYLQNEGERLLLEAMDELE VAFNNTNVRTDCNHIFLNFVPTVIMDPSKIEES VRSMVMRYGSRLWKLRVLQAELKINIRLTPTGKA IPIRLFLTNESGYYLDISLYKEVTDSRTAQIMF QAYGDKQGPLHGMLINTPYVTKDLLQSKRFQAQ SLGTTYIYDIPEMFRQSLIKLWESMSTQAFLPSP PLPSDMLTYTELVLDDQGQLVHMNRLPGGNEIG MVAWKMTFKSPEYPEGRDIIVIGNDITYRIGSF GPQEDLLFLRASELARAEGIPRIYVSANSGARIG LAEEIRHMFHVAWVDPEDPYKGYRYLYLTPQDY KRVSALNSVHCEHVEDEGESRYKITDIIGKEEG IGPENLRGSGMIAGESSLAYNEIITISLVTCRAI GIGAYLVRLGQRTIQVENSHLILTGAGALNKVL GREVYTSNNQLGGIQIMHNNGVTHCTVCDDFEG VFTVLHWLSYMPKSVHSSVPLLNSKDPIDRIIEF VPTKTPYDPRWMLAGRPHPTQKGQWLSGFFDYG SFSEIMQPWAQTVVVGRARLGGIPVGVVAVETR TVELSIPADPANLDSEAKIIQQAGQVWFPDSAFK TYQAIKDFNREGLPLMVFANWRGFSGGMKDMYD QVLKFGAYIVDGLRECCQPVLVYIPPQAELRGG SWVVIDSSINPRHMEMYADRESRGSVLEPEGTVE IKFRRKDLVKTMRRVDPVYIHLAERLGTPELST AERKELENKLKEREEFLIPIYHQVAVQFADLHD TPGRMQEKGVISDILDWKTSRTFFYWRLRRLLLE DLVKKKIHNANPELTDGQIQAMLRRWFVEVEGT VKAYVWDNNKDLAEWLEKQLTEEDGVHSVIEEN IKCISRDYVLKQIRSLVQANPEVAMDSIIHMTQH ISPTQRAEVIRILSTMDSPST*EELPACPCPVS GEKG*SCLLQL*PL**EGTGDPALESNGILLPL VSGYA*HPGM*DHRIPLQPTSHTYPIQYLLPWPG LVLHSLHRTEKAMKGTNMYHEVLLTKVGLPLLS *QPLGLPAWGSVRSCPAVSSPPHSWPHEPQPQA AEEG*GEEEASSPLFITPTLSPAHSRHWRGMIPS LTTLRYLL*RKIRA*NLLQAP*ELKDEGKTVSQ EAEKENRTSYS*FRGPQPWVQSLRTKGKVVVGL PLACTSLLD*LSHVAGSCKASA*GAPAVPQVVKP ELAEEEPEENCPFCTGGN*LFMPCGEPVR*IDS LFVLRTWKVVPMKPGAWMVLRG*WCLHTHSSLV PGLLS*QLTVLLSSPECRQAAGLPTALKGPW*QL HPQHQELAFLMREASRKHRIHMTLRLFTTQSWC CCPPGLLAPPDWHQGLPQVVERVYFQQLVYSRK ELTDSSVPKARVAGDQGWCSIRFL*CS*LHLSLM TKEEITKTFEKQWYERSWTSHSSEP*PCSLHTR TSSTSPSSGGICADRLAGLFNGSGLQVGTVWLG MERTAPRSQSLSPAALVEGTGVQHLQKRA*SGGG QFSVQENALTIAGYLLT**ELDSFLTRLFFYAF LQ*IKSHISTSGMKSCTPQEACPGMSSEAGWVT LIYLPSPHQIMTQTSMFPL*NPVMPPPPSPELLT VGLTLDKDFFKLEAQNMSNLTFPQPLKHARLLR QEEYK*WILTKTCLDGDRHIICSLRSQNSLHLS QNLMDTYCDEQELQMHSLHILLK*TSTFVEE

Frame 1

PWRPPPGAERPPPPSWPFPGPRRAPAAVPVPED WEDGAEPLA*LLIRPVITLPVWRVARCLRLPGA WGCLVPSGVR*GGPSRDCLGLGITFPSPPLLQQG KLRLRELGPGTASRGCLSSPGPEGLLVDEPD*F *GVKRVRFNQMLLERRNCLLWKEPSPLWASEAQ IEAQ**EDVVVYSDVNLEG*SLALSPRPGFTPFS CLSLPSSWDYRLECNGMILAHCNLRLPDSTDSP ASAS*VAGIIGACHNTQDQTYEVAFLRRFSDLM V*SSFRLLILDKLE*LTRAKRHSIQIRTLCLIFL LYHNWSHSCGQGTDFLDEFCPSVKQLYIPLEAL PLRDNVKTDKQASGAEWPLSWSDSPKKDPLGWA RWLTPIIPALWEAEAGGSRGQEFEASLANMSQ*V VFLGRIFLPCLRGLDLQNICQGLFSF*GFNPQS FLYPFCTSSIPILKLWCIKP*FRCLYIPLLWPE N*NRGSHLILSSLVVACFLSTCLLSHLTCFSPPC SLIIGIICFDWISEITSLDRAVLLPLDFMSPLF SWLNCPCKFGLFVLGFPCHVLLAARRGSGAFLR *LSEESDCC*KCLLQLKESC*DLLSS*TSFYISP RLLSVPLGNQLIVCVS*VCGGEKMQKGRERWGK KEIGNN*TKRL*FEAIRSILV*LKPGRRHSISC PPGF*AAATGGGTAACVYKAEI*RKSFHSFPILI WRVLQRKIRK*DITCFKGPACLACT**SRAETE RK*ILNEISLWLLQQNLLLALGEIK*LRRFLLL TMALQQ*NACGLSVGGLMKCFEMNVQLDSLSWSH LKTLKPMQNTLRWQITMCQCLEDQTTTTMQMWN *FLILLKGSQYKQCGLAGVMLLRIPNYRNFS*K MALPSWVLQARPCGL*GIRLHLP*WLKLQVSQLF PGAAVVFVWTGRKMIFQNVS*MFPRSYMKKVM* KMWMMGYRQLRKLDIQ**SRPQREEEGRELEKS TMQMTSLISSDRFKLKFLDLPYL**D*PNNLVIW RCRS*RTNMAMLSLCLVVIALYNAGIRRLLKKH LLLLLLQQYLNTWNSVR*NLPKWWVM*VLGLWN TCTARMAASTFWN*ILGCR*STLVQRWWLMSISL QHSSRLPWGFLYIESRISV*CMGYLPGVILPLI LKILHTFLVQGAMLLLLGSLVKIQMRVLSPAQE QFRS*ISAAIRMFGDISVLLLQGDFMNLLILSLV TAFLGEKTEKRQFQTWWWL*RSCLFGVTFELQL NT*SNC*RLKAFR*TELILAGWTD**QKKYRLS DLTPCWGLCVVPSTWQM*ACGIASLTSFTP*KGV KSFLLIHF*IQ*MLNLSMRESSMYLR*LDSPPT PMW*S*MAHV*K*MYIG*VTVDCSCPMMAAVIL RI*KRKWIDIASQLAIKPVCLRRKMTHR*CAHLL LGS*SSTL*KMEVMCLPASAMLRLR**RW**P* QLWSLAVSITSSDLEQLLTLAVY*PKCNWTTPA RFSRLNFTQVVCHGSRARHSEARNSIECSIMSWI IWSM**MDTAFQILSLAAR*KTG*SD**KPSEI PPCLS*NCKIL*PVCLAAFPPMWRSLSRRKWLS MLATSHQSSVSFPASRLQTS*IAMQLH*TGNLNG KSSL*ILRALFSWYRGTEVASEAT*RLW*WICS GSTCE*RHNSRMVTMTNVYSPSEKRIKVT*TLY *TTSSLTLKSPRRIFWSQCLLISCVAGTLLSLMS C*IFSQS*LNSVRPPMPK*HFEHARFLLPPICH HMSFAITK*SLSSYQLLTCMDINFALRTCRNSS YQKHLFLMSYQTSSITATK**GWQLWRCMFEGLI LPMNLTAYNTASLRTTPVWWNSSSCCPHLIQTE GTSLR*TECPSPPTSTTMA*PM*LVSAMYCWTT HSLHLVSGWAEWSLFGLLKILSGSLMK*WAASLT PHPRVPHSLRQVTRLFMMRIRFPGMNQFTFSMW LSRLTVILRMTGWQLCSENLPSKIKLPWLTMGS GALLSWLHKRISESRSTMRWIGDFIENSLNFLHS EQGISLRRIVSIVIWSLLWLSS*S*TG*EILTS LPFHVLITRCTCISGQPRWKWAQK*QTTGSLFV QSSGILIWSPRKLLLNICKMKGSGYSWKPWMSWK LLLTIQMSALTVTTSSSTLCPRLSWTHQRLRNP CGAW*CGMEVACGNCASSRQN*KSTFA*RQLEK QFPSASS*QTSLAITWISAYTRK*LTPGQHRSCF RHMETNRDHCMEC*SILHM*PKTCCNQRGSRHN P*GQHTYMISQRCFGSP*SNSGSLCPLKHFFHL PLCLLTC*LTLNWYWMIKVSWST*TGFQEEMRLA W*LGK*PLKVLNIQKAEISLLLAMTSHTELGPL GLKRICYFSELPNLLGQKVFHASMYQPTVEQES DWQKKFAICFMWPG*ILRILTRDTGIYI*LLKII RESVLSTLSIVNTWKMKENPGTR*QILLGKKRE LDPRTFEVLE*LLENPHWPIMRSLPSAW*RAGP LGLGLTLSGWDREPSRLRILT*F*QELEPSTKSS GGKCTPPITSWGASRLCTTMG*PTALCVMTLKG FSLSCTGCLTCPRACTVQFLF*TQRIL*TESSS LFPQRPHTILDGC*QAVLTQPKKVSG*VAFLTMD LSQRLCSPGHRLWWLVEPG*EEYLWELLL*KPE Q*N*VSQLIQQTWILKPR*SSRLARFGSQILRL RHIRPSRTSTGKGCL*WSLPTGEASLVE*KICTT KC*SLVLTLWMA*GSAASLCWFTFLPRLSCGVA PGW*LTPPSTPGTWRCMLTEKAGDLFWSQKGQ* KSNSAERIW*KPCVGWTQSTSTWLSDWGPQS*AQ LSGRSWRTS*RSGRNS*FPFTIR*PCSLLTCTT HQAGCRRRVLLAISWIGKHPVPSSTGG*GVFCW RTWSRRKSTMPTLS*LMARFKPC*GAGLWKWKEQ *RLMFGTIIRIWRSG*RNS*QRRMVFTR**RKT SNASAETTSSSKSAAWSRPIQRLPWIPSSI*RS TYHPLSEQKSYGSSPQWIPLPRRKSFLPVPALSL EKRARAAFYNCNHCNEKAQETQHWSQMAFYFLS FQVMHDILGCKITESPSSPPVTPTPFSIYYPGQ A*SSTPCTGLRRQ*KVQTCTMRSY*PK*GCPSCP DSPLASQHGEA*GVAQQ*AAPLTPGPMSRSHRQ QRRAKERRKPQVHCLLPRLLAQHTVGTGEE*FP V*PHYGTFYEEKLEHKIYYKLHRNSKMRAKL*AK KQRKKIEPVILDLGDLNLGFSL*GQRER*LLAC LSPARHCWTSCRMWLGAARPVLEGPQQFHRW*S LSWQRRSQKRTALSALVETSYLCHVESQ*DR*IV CLF*GLGKLFL*SLELGWF*EVNGASTLTLP*F QDYCPSS*RFYSLPQSVDRQQVSPQL*KDPGDS YTLSTRSWPS**GRLPGNTEST*P*DYLQLSHGA AVLQAYWPLLTGIRGFLRWWREFTFNN*FIQEK NLLIPLFLKQEWQVIRAGVASGSFSAANCICH* *PRRKSLRHLRSSGMNVLGQATVLSLNPVVCTQE RAPPPLLQEESVRIDWLDFSMVLGCRWALYGWV WSGQPPGVRASARLPWWKVQVFSTFRKGHKVVG DNSQSRKMH*PLLAICLPSKNWIHF*PDYSSMLF CNKSNPTYLQVV*SPAPPRRPVQACLQRQGGLH SFTSPLPTKL*HKRVCFLSRTL*CLLPHPQSSL L*VLPWTRIFSSWRHRT*AI*HSHSPSNMQGY*G RRSINDGY*PRPAWTETAILSVLFVHKTAFTCL RI*WTHTVMSRSFRCTLYTFC*NKPLHL*KS

Frame 2

RGGPRRVLSARHRPLGLFPVPAARLLLSPCPRT GRMGLSRLPDF*SDQ*SLCPCGAWPVA*GFLAR GAVWSPPECGEAGRAGTAWVWG*RSHLHPCCSK GN*G*GNWAQGRRAVAASPVRAPKGCSWMNQTDF KG*RGCVSIRCFWNVEIVFFGKNHPLFGLQRPK LRRNDERMWWSTLMSILRARVSLCHPGLGSHHS PASASQVAGTTGWSAMA*SWLTATSASRIQRILL PQPPE*LGL*VPATTPRTRLMKWPS*GDFLTLW YEVPSGS*FWINWSD*QEQRDIVFR*GLCVLFF FYITTGATVVGKALTFLMNSVHL*SSYISHWRLC LSETT*RRISRHQEQSGLSAGQILRRRIL*AGH GGSHL*SQHFGRPRQVDHEVRSSRPAWPICLSK *SF*AGFFFPA*GG*TSKIFVRVSFPFKGLTHNL FCIRFVPAPFLFSSFGA*NLSLGVYIYHYFGLK IRIVAHT*F*VP**WRVSFLRAYFPT*PAFPHR AV**LVLFVLIGSQKLPL*TELCSSLWIS*AHYF LGLIVLVNLVFLSWAFPVMCSWQPGEAVELFSV DCQKKVTVVENVCCN*RRAAKIYFLVKQAFIFL PGSSQFPWEIN*LCV*AKCVEERRCKKEEKGGER RKLGTIRQKDYSLRPSGVF*SD*SQAEGTVSLV LLGFKQLQQEEELRLVFTRPKSEEKASILFPS* YGGFSRGK*GNEILHASKVQHVWLAPSKAGPRQK ENRFSTRFHCGFSSRICYSLWGK*SD*EGSYC* QWHCSSEMHAVYP*VVL*NVSK*TCN*IRCHGH T*RP*SQCRIH*DGRSLCASAWRTKQQQLCKCGI NS*YC*KDPSTSSVGWLGSCF*ESQTTGTSLEK WHCLHGSSKPGHVGFRG*DCIFHSGSNCRYPNS SLERQWSSCGLAGK*FFKTYLKCSPGAI*KRLCE RCG*WATGS*GSWISSNDQGLRGRRREGN*KSQ QCR*LP*SLQTGSS*SSWISHICDETSQTISSS GGADLSGPIWQCYLFVWS*LLCTTQASEDY*RST CYYCYSSSI*THGTVCGETCQNGGLCECWDCGI PVQPGWQLLLSGIESSAAGRAPLYRDGG*CQSP CSTAPDCHGDSSI*NQGYPYDVWGISLG*FSH*F *RFCTRSLSKGPCYCCSDH**KSR*GF*AQLRN SSGAKFPQQ*ECLGIFQCCCCRGTS*IC*FSVW SLLFLGRKQRRGNFKHGGGFEGAVYSG*LSNYS* IPDQIVRD*KLSDEQN*YWLAGQTDSRKSTG*A T*HHVGGCVWCPPRGRCEPAE*RL*LPSLLRKG SSPSCSYTSEYSRC*TYL*GSQVCT*GDSTVPQL LCGDHEWLMCRSRCTSAE*RWTALVL*WQQLYY VYERGSG*ISHHNWQ*NLCV*EGK*PIGDALTF CWEVNPVHCRRWRSCVCRPVLC*D*GNEDGNDLN SCGVWLYPLRQATWSSS*PWLCTSQNATGQPQQ GSAG*TSHR*SATDPEHGTQRRETPSSVPLCPG *SGQCNEWILPSRSFL*QQGKRLGRAIDENPQRS LPASPRIARYYDQCVWPHSPQCGEVYQEGNGSV C*QHHISPLSVSQPADCKHPR*PCSYIEPEI*T GSLLYEYSEHCSAGTEVPKWHPRPHEGCGDGSAP AVPASRDTIPEWSL*QMCIRPPRRE*K*HEHCT ELHLLSRSSHQEESSGHNAY*SVVWPGPYSH** AAEYSHRANSTQ*DHQCQSSTSSTPGSYCLPFAI I*ASP*PSRVYLPISY*HVWTSILH*EPAETHP IRNIYF*CPTKLLLSQQPSSEDGSSGGVCSKGL YCL*T*QRTTPPA*GQHLCGGIPVHAAHISSKQR EHPYAKQNVLLLQPQPLWHDPCS*CQRCTVGQL IHSTLSADGRNGLFSDF*RFCQDL**SDGLLL* LPTPESHIP*GRSHVSL**G*GSQG*TNSHSQCG YQD*L*Y*G*QAGSYVQRIYPAK*SYPG*PWDP APYFPGCTKGFQKAGQL*GGSEIS*RIP*IFYI PSKG*V*GGSYLSSSGACSGFPVRAEPDEKF*PH CHSMC*SQDAPVSRGSQGGSGHRSDRLQVLCSC NHQAF*SGHQGSFF*ISAK*RGAATPGSHG*VG SCF*QYKCPH*L*PHLPQLCAHGYHGPIKD*GIR AEHGNAVWKSPVEIARPPGRTENQHSPDANWKS NSHPPLPDKRVWLLLGYQPIQGSD*LQDSTDHV SGIWRQTGTTAWNVNQYSICDQRPAAIKEVPGTI LRDNIHI*YPRDVSAVPDQTLGVYVHSSISSIS PSAF*HADLH*TGTG*SRSAGPHEQASRRK*DW HGSLENDL*KS*ISRRPRYHCYWQ*HHIPNWVLW ASRGFVISQSFRTC*GRRYSTHLCISQQWSKNR TGRRNSPYVSCGLGRS*GSLQGIQVFISDSSRL *ESQCSQLCPL*TRGR*RRIQVQDNRYYWERRGN WTREPSRFWNDCWRILIGL**DHYHQPGDVPGH WDWGLPCPAGTENHPG*EFSLNSNRSWSPQQSP RAGSVHLQ*PAGGHPDYAQQWGDPLHCV**L*RG FHCPALAVLHAQERAQFSSSSELKGSYRQNHRV CSHKDPIRSSMDASRPSSPNPKRSVVEWLF*LW IFLRDYAALGTDCGGW*SQARRNTCGSCCCRNPN SRTKYPS*SSKPGF*SQDNPAGWPGLVPRFCV* DISGHQGLQPGRAASDGLCQLERLLWWNERYVR PSAEVWCLHCGWLEGVLPACAGLHSSPG*AAGWL LGGD*LLHQPPAHGDVC*PRKQGICSGARRDSR NQIPQKGSGENHASGGPSLHPLG*AIGDPRAKH S*AEGVGEQVEGAGGIPNSHLPSGSRAVC*LARH TRPDAGEGCY*RYPGLENIPYLLLLAAEASSAG GPGQEENPQCQP*AD*WPDSSHVKALVCGSGRN SEGLCLGQ**GSGGVARETADRGGWCSLGNRGKH QMHQQRLRPQANPQLGPGQSRGCHGFHHPYDAA HITHSASRSHTDPLHNGFPFHVGRASCLSLPCL WRKGLELPFTTVTTVMRRHRRPSTGVKWHFTSSR FRLCMTSWDVRSQNPPPAHQSHLPHSVFITLAR PSPPLPAQD*EGNERYKHVP*GLTNQSRAAPPV LTAPWPPSMGKREELPSSEQPPSLLAP*AAATGS RGGLRRGGSLKSIVYYPDS*PSTQ*ALERNDSQ FNHTTVPFMKKN*SIKSTTSSIGTQR*GQNCEP RSRERK*NQLFLI*GTSTLGSVSEDKGKGSCWPA SRLHVTAGLAVACGWELQGQCLRGPSSSTGGEA *VGRGGARRELPFLHWWKLVIYAMWRASEIDR* SVCFEDLESCSYEAWSLDGFERLMVPPHSLFPSS RITVLAANGSTLFPRV*TGSRSPHSSERTLVTA TPSAPGAGLPDEGGFQETQNPHDLKIIYNSVMV LLSSRLTGPS*LASGASSGGGESLLSTTSLFKKR TY*FLCS*SKSGR*SGLV*HPVPLVQLTAFVTD DQGGNH*DI*EAVV*TFLDKPQF*ALTL*FAHK NELHLPFFRRNLCG*IGWTFQWFWVAGGHCMAGY GADSPQESEPQPGCPGGRYRCSAPSEKGIKWWG TILSPGKCIDHCWLFAYLVRIGFIFDQIILLCF FAINQIPHIYKWYEVLHPPGGLSRHVFRGRVGYT HLPPLSPPNYDTNEYVSSLEPCNASSPIPRAPY CRSYPGQGFFQVGGTEHEQSDIPTAPQTCKATK AGGV*MMDIDQDLLGRRPPYYLFSSFTKQPSLVS EFDGHIL**AGASDALFTHFVEINLYICRRV

Sequence ACACA.kAug05

ACACA.F5 (forward primer)
ACACA.R5 (reverse primer)
Mutually exclusive exon skipping

Frame 0

AVEAPAGC*APATALLAFSRSPPRACCCPRARG LGGWG*AACLTFDPTSNHFARVARGPLPEASWRV GLFGPLRSAVRRAEPGLPGFGDNVPISTPVAAR EIEAEGTGPRDGEPWLPLQSGPRRAARG*TRLI LRGEEGAFQSDASGTSKLSSLERTIPSLGFRGPN *GAMMRGCGGLL*CQS*GLGSCYVTQPGVELCD QDSLKPPTPGLKQSSHLSHPSSWDYRLECNGMI LAHCNLRLPDSTDSPASAS*VAGIIGACHNTQDQ TYEVAFLRRFSDLMV*SSFRLLILDKLE*LTRA KRHSIQIRTLCLIFLLYHNWSHSCGQGTDFLDE FCPSVKQLYIPLEALPLRDNVKTDKQASGAEWPL SWSDSPKKDPLGWARWLTPIIPALWEAEAGGSR GQEFEASLANMVFLEVDIYSDSKNYKSCKSSFW RNNG*TISLGPTSGAEPALSIHNRFCV*R*LRG* DQQPGEVGPTGGEGGLLVTCFCWLRYTL*FGDL *PTGWLGLAHKVQHVWLAPSKAGPRQKENRFST RFHCGFSSRICYSLWGK*SD*E

Frame 1

PWRPPPGAERPPPPSWPFPGPRRAPAAVPVPED WEDGAEPLA*LLIRPVITLPVWRVARCLRLPGA WGCLVPSGVR*GGPSRDCLGLGITFPSPPLLQQG KLRLRELGPGTASRGCLSSPGPEGLLVDEPD*F *GVKRVRFNQMLLERRNCLLWKEPSPLWASEAQ IEAQ**EDVVVYSDVNLEG*GLAMSPSLEWNCVI KTH*SLQLLGSSNPPTSATQVAGTTGWSAMA*S WLTATSASRIQRILLPQPPE*LGL*VPATTPRT RLMKWPS*GDFLTLWYEVPSGS*FWINWSD*QEQ RDIVFR*GLCVLFFFYITTGATVVGKALTFLMN SVHL*SSYISHWRLCLSETT*RRISRHQEQSGL SAGQILRRRIL*AGHGGSHL*SQHFGRPRQVDHE VRSSRPAWPIWSFWKWISTQTVRIIRAVRAHFG GIMDEPSPLAQPLELNQHSRFIIGSVSEDNSED EISNLVKLDLLEEKEGSLSPASVGSDTLSDLGIS SLQDGLALHIRSSMSGLHLVKQGRDRKKIDSQR DFTVASPAEFVTRFGGNKVIEK

Frame 2

RGGPRRVLSARHRPLGLFPVPAARLLLSPCPRT GRMGLSRLPDF*SDQ*SLCPCGAWPVA*GFLAR GAVWSPPECGEAGRAGTAWVWG*RSHLHPCCSK GN*G*GNWAQGRRAVAASPVRAPKGCSWMNQTDF KG*RGCVSIRCFWNVEIVFFGKNHPLFGLQRPK LRRNDERMWWSTLMSILRARVLLCHPAWSGIV* SRLTEASNSWAQAILPPQPPK*LGLQAGVQWHDL GSLQPPPPGFNGFSCLSLLSSWDYRCLPQHPGP DL*SGLPEEIF*PYGMKFLQALNSG*TGVINKS KET*YSDKDFVSYFSFISQLEPQLWARH*LS**I LSICKAAIYPTGGFASQRQREDG*AGIRSRVAS QLVRFSEEGSSRLGTVAHTYNPSTLGGRGRWIT RSGVRGQPGQYGLSGSGYLLRQ*EL*EL*ELILE E*WMNHLPWPNLWS*TSTLDS**VLCLKITQRM RSATW*SWTYWRRRRAPCHLLLLAQIHSLIWGS LAYRMAWPCT*GPACLACT**SRAETERK*ILNE ISLWLLQQNLLLALGEIK*LR