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Sequences

Sequence NM_172354

GCTCGGGCCACGCCCACCTGTCCTGCAGCACTGGATGCTTTGTGAGTTGGGGATTGTTGCGTCCCATATCTGGACCCAGAAGGGACTTCCCTGCTCGGCT
GGCTCTCGGTTTCTCTGCTTTCCTCCGGAGAAATAACAGCGTCTTCCGCGCCGCGCATGGAGCCTCCCGGCCGCCGCGAGTGTCCCTTTCCTTCCTGGCG
CTTTCCTGGGTTGCTTCTGGCGGCCATGGTGTTGCTGCTGTACTCCTTCTCCGATGCCTGTGAGGAGCCACCAACATTTGAAGCTATGGAGCTCATTGGT
AAACCAAAACCCTACTATGAGATTGGTGAACGAGTAGATTATAAGTGTAAAAAAGGATACTTCTATATACCTCCTCTTGCCACCCATACTATTTGTGATC
GGAATCATACATGGCTACCTGTCTCAGATGACGCCTGTTATAGAGAAACATGTCCATATATACGGGATCCTTTAAATGGCCAAGCAGTCCCTGCAAATGG
GACTTACGAGTTTGGTTATCAGATGCACTTTATTTGTAATGAGGGTTATTACTTAATTGGTGAAGAAATTCTATATTGTGAACTTAAAGGATCAGTAGCA
ATTTGGAGCGGTAAGCCCCCAATATGTGAAAAGGTTTTGTGTACACCACCTCCAAAAATAAAAAATGGAAAACACACCTTTAGTGAAGTAGAAGTATTTG
AGTATCTTGATGCAGTAACTTATAGTTGTGATCCTGCACCTGGACCAGATCCATTTTCACTTATTGGAGAGAGCACGATTTATTGTGGTGACAATTCAGT
GTGGAGTCGTGCTGCTCCAGAGTGTAAAGTGGTCAAATGTCGATTTCCAGTAGTCGAAAATGGAAAACAGATATCAGGATTTGGAAAAAAATTTTACTAC
AAAGCAACAGTTATGTTTGAATGCGATAAGGGTTTTTACCTCGATGGCAGCGACACAATTGTCTGTGACAGTAACAGTACTTGGGATCCCCCAGTTCCAA
AGTGTCTTAAAGTGCTGCCTCCATCTAGTACAAAACCTCCAGCTTTGAGTCATTCAGTGTCGACTTCTTCCACTACAAAATCTCCAGCGTCCAGTGCCTC
AGGATATCCTAAACCTGAGGAAGGAATACTTGACAGTTTGGATGTTTGGGTCATTGCTGTGATTGTTATTGCCATAGTTGTTGGAGTTGCAGTAATTTGT
GTTGTCCCG
TACAGATATCTTCAAAGGAGGAAGAAGAAAGGCACATACCTAACTGATGAGACCCACAGAGAAGTAAAATTTACTTCTCTCTGAGAAGGAG
AGATGAGAGAAAGGTTTGCTTTTATCATTAAAAGGAAAGCAGATGGTGGAGCTGAATATGCCACTTACCAGACTAAATCAACCACTCCAGCAGAGCAGAG
AGGCTGAATAGATTCCACAACCTGGTTTGCCAGTTCATCTTTTGACTCTATTAAAATCTTCAATAGTTGTTATTCTGTAGTTTCACTCTCATGAGTGCAA
CTGTGGCTTAGCTAATATTGCAATGTGGCTTGAATGTAGGTAGCATCCTTTGATGCTTCTTTGAAACTTGTATGAATTTGGGTATGAACAGATTGCCTGC
TTTCCCTTAAATAACACTTAGATTTATTGGACCAGTCAGCACAGCATGCCTGGTTGTATTAAAGCAGGGATATGCTGTATTTTATAAAATTGGCAAAATT
AGAGAAATATAGTTCACAATGAAATTATATTTTCTTTGTAAAGAAAGTGGCTTGAAATCTTTTTTGTTCAAAGATTAATGCCAACTCTTAAGATTATTCT
TTCACCAACTATAGAATGTATTTTATATATCGTTCATTGTAAAAAGCCCTTAAAAATATGTGTATACTACTTTGGCTCTTGTGCATAAAAACAAGAACAC
TGAAAATTGGGAATATGCACAAACTTGGCTTCTTTAACCAAGAATATTATTGGAAAATTCTCTAAAAGTTAATAGGGTAAATTCTCTATTTTTTGTAATG
TGTTCGGTGATTTCAGAAAGCTAGAAAGTGTATGTGTGGCATTTGTTTTCACTTTTTAAAACATCCCTAACTGATCGAATATATCAGTAATTTCAGAATC
AGATGCATCCTTTCATAAGAAGTGAGAGGACTCTGACAGCCATAACAGGAGTGCCACTTCATGGTGCGAAGTGAACACTGTAGTCTTGTTGTTTTCCCAA
AGAGAACTCCGTATGTTCTCTTAGGTTGAGTAACCCACTCTGAATTCTGGTTACATGTGTTTTTCTCTCCCTCCTTAAATAAAGAGAGGGGTTAAACATG
CCCTCTAAAAGTAGGTGGTTTTGAAGAGAATAAATTCATCAGATAACCTCAAGTCACATGAGAATCTTAGTCCATTTACATTGCCTTGGCTAGTAAAAGC
CATCTATGTATATGTCTTACCTCATCTCCTAAAAGGCAGAGTACAAAGTAAGCCATGTATCTCAGGAAGGTAACTTCATTTTGTCTATTTGCTGTTGATT
GTACCAAGGGATGGAAGAAGTAAATATAGCTCAGGTAGCACTTTATACTCAGGCAGATCTCAGCCCTCTACTGAGTCCCTTAGCCAAGCAGTTTCTTTCA
AAGAAGCCAGCAGGCGAAAAGCAGGGACTGCCACTGCATTTCATATCACACTGTTAAAAGTTGTGTTTTGAAATTTTATGTTTAGTTGCACAAATTGGGC
CAAAGAAACATTGCCTTGAGGAAGATATGATTGGAAAATCAAGAGTGTAGAAGAATAAATACTGTTTTACTGTCCAAAGACATGTTTATAGTGCTCTGTA
AATGTTCCTTTCCTTTGTAGTCTCTGGCAAGATGCTTTAGGAAGATAAAAGTTTGAGGAGAACAAACAGGAATTCTGAATTAAGCACAGAGTTGAAGTTT
ATACCCGTTTCACATGCTTTTCAAGAATGTCGCAATTACTAAGAAGCAGATAATGGTGTTTTTTAGAAACCTAATTGAAGTATATTCAACCAAATACTTT
AATGTATAAAATAAATATTATACAATATACTTGTATAGCAGTTTCTGCTTCACATTTGATTTTTTCAAATTTAATATTTATATTAGAGATCTATATATGT
ATAAATATGTATTTTGTCAAATTTGTTACTTAAATATATAGAGACCAGTTTTCTCTGGAAGTTTGTTTAAATGACAGAAGCGTATATGAATTCAAGAAAA
TTTAAGCTGCAAAAATGTATTTGCTATAAAATGAGAAGTCTCACTGATAGAGGTTCTTTATTGCTCATTTTTTAAAAAATGGACTCTTGAAATCTGTTAA
AATAAAATTGTACATTTGGAGATGTTTCA
  • refseq_CD46.F1 (forward primer)
  • refseq_CD46.R1 (reverse primer)
  • Single exon skipping

Frame 0

ARATPTCPAALDAL*VGDCCVPYLDPEGTSLLG
WLSVSLLSSGEITASSAPRMEPPGRRECPFPSWR
FPGLLLAAMVLLLYSFSDACEEPPTFEAMELIG
KPKPYYEIGERVDYKCKKGYFYIPPLATHTICD
RNHTWLPVSDDACYRETCPYIRDPLNGQAVPANG
TYEFGYQMHFICNEGYYLIGEEILYCELKGSVA
IWSGKPPICEKVLCTPPPKIKNGKHTFSEVEVF
EYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSV
WSRAAPECKVVKCRFPVVENGKQISGFGKKFYY
KATVMFECDKGFYLDGSDTIVCDSNSTWDPPVP
KCLKVLPPSSTKPPALSHSVSTSSTTKSPASSAS
GYPKPEEGILDSLDVWVIAVIVIAIVVGVAVIC
VVP
YRYLQRRKKKGTYLTDETHREVKFTSL*EG
EMRERFAFIIKRKADGGAEYATYQTKSTTPAEQR
G*IDSTTWFASSSFDSIKIFNSCYSVVSLS*VQ
LWLS*YCNVA*M*VASFDASLKLV*IWV*TDCL
LSLK*HLDLLDQSAQHAWLY*SRDMLYFIKLAKL
EKYSSQ*NYIFFVKKVA*NLFCSKINANS*DYS
FTNYRMYFIYRSL*KALKNMCILLWLLCIKTRT
LKIGNMHKLGFFNQEYYWKIL*KLIG*ILYFL*C
VR*FQKARKCMCGICFHFLKHP*LIEYISNFRI
RCILS*EVRGL*QP*QECHFMVRSEHCSLVVFP
KRTPYVLLG*VTHSEFWLHVFFSPSLNKERG*TC
PLKVGGFEENKFIR*PQVT*ES*SIYIALASKS
HLCICLTSSPKRQSTK*AMYLRKVTSFCLFAVD
CTKGWKK*I*LR*HFILRQISALY*VP*PSSFFQ
RSQQAKSRDCHCISYHTVKSCVLKFYV*LHKLG
QRNIALRKI*LENQECRRINTVLLSKDMFIVLC
KCSFPL*SLARCFRKIKV*GEQTGILN*AQS*SL
YPFHMLFKNVAITKKQIMVFFRNLIEVYSTKYF
NV*NKYYTIYLYSSFCFTFDFFKFNIYIRDLYM
YKYVFCQICYLNI*RPVFSGSLFK*QKRI*IQEN
LSCKNVFAIK*EVSLIEVLYCSFFKKWTLEIC*
NKIVHLEMF

Frame 1

LGPRPPVLQHWMLCELGIVASHIWTQKGLPCSA
GSRFLCFPPEK*QRLPRRAWSLPAAASVPFLPG
AFLGCFWRPWCCCCTPSPMPVRSHQHLKLWSSLV
NQNPTMRLVNE*IISVKKDTSIYLLLPPILFVI
GIIHGYLSQMTPVIEKHVHIYGIL*MAKQSLQM
GLTSLVIRCTLFVMRVIT*LVKKFYIVNLKDQ*Q
FGAVSPQYVKRFCVHHLQK*KMENTPLVK*KYL
SILMQ*LIVVILHLDQIHFHLLERARFIVVTIQ
CGVVLLQSVKWSNVDFQ*SKMENRYQDLEKNFTT
KQQLCLNAIRVFTSMAATQLSVTVTVLGIPQFQ
SVLKCCLHLVQNLQL*VIQCRLLPLQNLQRPVP
QDILNLRKEYLTVWMFGSLL*LLLP*LLELQ*FV
LSR
TDIFKGGRRKAHT*LMRPTEK*NLLLSEKE
R*EKGLLLSLKGKQMVELNMPLTRLNQPLQQSR
EAE*IPQPGLPVHLLTLLKSSIVVIL*FHSHECN
CGLANIAMWLECR*HPLMLL*NLYEFGYEQIAC
FPLNNT*IYWTSQHSMPGCIKAGICCIL*NWQN
*RNIVHNEIIFSL*RKWLEIFFVQRLMPTLKIIL
SPTIECILYIVHCKKPLKICVYYFGSCA*KQEH
*KLGICTNLASLTKNIIGKFSKS**GKFSIFCN
VFGDFRKLESVCVAFVFTF*NIPN*SNISVISES
DASFHKK*EDSDSHNRSATSWCEVNTVVLLFSQ
RELRMFS*VE*PTLNSGYMCFSLPP*IKRGVKH
AL*K*VVLKRINSSDNLKSHENLSPFTLPWLVKA
IYVYVLPHLLKGRVQSKPCISGR*LHFVYLLLI
VPRDGRSKYSSGSTLYSGRSQPSTESLSQAVSF
KEASRRKAGTATAFHITLLKVVF*NFMFSCTNWA
KETLP*GRYDWKIKSVEE*ILFYCPKTCL*CSV
NVPFLCSLWQDALGR*KFEENKQEF*IKHRVEV
YTRFTCFSRMSQLLRSR*WCFLET*LKYIQPNTL
MYKINIIQYTCIAVSASHLIFSNLIFILEIYIC
INMYFVKFVT*IYRDQFSLEVCLNDRSVYEFKK
I*AAKMYLL*NEKSH**RFFIAHFLKNGLLKSVK
IKLYIWRCF

Frame 2

SGHAHLSCSTGCFVSWGLLRPISGPRRDFPARL
ALGFSAFLRRNNSVFRAAHGASRPPRVSLSFLA
LSWVASGGHGVAAVLLLRCL*GATNI*SYGAHW
*TKTLL*DW*TSRL*V*KRILLYTSSCHPYYL*S
ESYMATCLR*RLL*RNMSIYTGSFKWPSSPCKW
DLRVWLSDALYL**GLLLNW*RNSIL*T*RISS
NLER*APNM*KGFVYTTSKNKKWKTHL**SRSI*
VS*CSNL*L*SCTWTRSIFTYWREHDLLW*QFS
VESCCSRV*SGQMSISSSRKWKTDIRIWKKILL
QSNSYV*MR*GFLPRWQRHNCL*Q*QYLGSPSSK
VS*SAASI*YKTSSFESFSVDFFHYKISSVQCL
RIS*T*GRNT*QFGCLGHCCDCYCHSCWSCSNL
CCP
VQISSKEEEERHIPN**DPQRSKIYFSLRRR
DERKVCFYH*KESRWWS*ICHLPD*INHSSRAE
RLNRFHNLVCQFIF*LY*NLQ*LLFCSFTLMSA
TVA*LILQCGLNVGSIL*CFFETCMNLGMNRLPA
FP*ITLRFIGPVSTACLVVLKQGYAVFYKIGKI
REI*FTMKLYFLCKESGLKSFLFKD*CQLLRLF
FHQL*NVFYISFIVKSP*KYVYTTLALVHKNKNT
ENWEYAQTWLL*PRILLENSLKVNRVNSLFFVM
CSVISES*KVYVWHLFSLFKTSLTDRIYQ*FQN
QMHPFIRSERTLTAITGVPLHGAK*TL*SCCFPK
ENSVCSLRLSNPL*ILVTCVFLSLLK*REGLNM
PSKSRWF*RE*IHQITSSHMRILVHLHCLG**K
PSMYMSYLIS*KAEYKVSHVSQEGNFILSICC*L
YQGMEEVNIAQVALYTQADLSPLLSPLAKQFLS
KKPAGEKQGLPLHFISHC*KLCFEILCLVAQIG
PKKHCLEEDMIGKSRV*KNKYCFTVQRHVYSAL*
MFLSFVVSGKML*EDKSLRRTNRNSELSTELKF
IPVSHAFQECRNY*EADNGVF*KPN*SIFNQIL
*CIK*ILYNILV*QFLLHI*FFQI*YLY*RSIYV
*ICILSNLLLKYIETSFLWKFV*MTEAYMNSRK
FKLQKCICYKMRSLTDRGSLLLIF*KMDS*NLL
K*NCTFGDVS

Sequence NM_172360

GCTCGGGCCACGCCCACCTGTCCTGCAGCACTGGATGCTTTGTGAGTTGGGGATTGTTGCGTCCCATATCTGGACCCAGAAGGGACTTCCCTGCTCGGCT
GGCTCTCGGTTTCTCTGCTTTCCTCCGGAGAAATAACAGCGTCTTCCGCGCCGCGCATGGAGCCTCCCGGCCGCCGCGAGTGTCCCTTTCCTTCCTGGCG
CTTTCCTGGGTTGCTTCTGGCGGCCATGGTGTTGCTGCTGTACTCCTTCTCCGATGCCTGTGAGGAGCCACCAACATTTGAAGCTATGGAGCTCATTGGT
AAACCAAAACCCTACTATGAGATTGGTGAACGAGTAGATTATAAGTGTAAAAAAGGATACTTCTATATACCTCCTCTTGCCACCCATACTATTTGTGATC
GGAATCATACATGGCTACCTGTCTCAGATGACGCCTGTTATAGAGAAACATGTCCATATATACGGGATCCTTTAAATGGCCAAGCAGTCCCTGCAAATGG
GACTTACGAGTTTGGTTATCAGATGCACTTTATTTGTAATGAGGGTTATTACTTAATTGGTGAAGAAATTCTATATTGTGAACTTAAAGGATCAGTAGCA
ATTTGGAGCGGTAAGCCCCCAATATGTGAAAAGGTTTTGTGTACACCACCTCCAAAAATAAAAAATGGAAAACACACCTTTAGTGAAGTAGAAGTATTTG
AGTATCTTGATGCAGTAACTTATAGTTGTGATCCTGCACCTGGACCAGATCCATTTTCACTTATTGGAGAGAGCACGATTTATTGTGGTGACAATTCAGT
GTGGAGTCGTGCTGCTCCAGAGTGTAAAGTGGTCAAATGTCGATTTCCAGTAGTCGAAAATGGAAAACAGATATCAGGATTTGGAAAAAAATTTTACTAC
AAAGCAACAGTTATGTTTGAATGCGATAAGGGTTTTTACCTCGATGGCAGCGACACAATTGTCTGTGACAGTAACAGTACTTGGGATCCCCCAGTTCCAA
AGTGTCTTAAAGTGCTGCCTCCATCTAGTACAAAACCTCCAGCTTTGAGTCATTCAGTGTCGACTTCTTCCACTACAAAATCTCCAGCGTCCAGTGCCTC
AGGATATCCTAAACCTGAGGAAGGAATACTTGACAGTTTGGATGTTTGGGTCATTGCTGTGATTGTTATTGCCATAGTTGTTGGAGTTGCAGTAATTTGT
GTTGTCCCG
TACAGATATCTTCAAAGGAGGAAGAAGAAAGGGAAAGCAGATGGTGGAGCTGAATATGCCACTTACCAGACTAAATCAACCACTCCAGCAG
AGCAGAGAGGCTGAATAGATTCCACAACCTGGTTTGCCAGTTCATCTTTTGACTCTATTAAAATCTTCAATAGTTGTTATTCTGTAGTTTCACTCTCATG
AGTGCAACTGTGGCTTAGCTAATATTGCAATGTGGCTTGAATGTAGGTAGCATCCTTTGATGCTTCTTTGAAACTTGTATGAATTTGGGTATGAACAGAT
TGCCTGCTTTCCCTTAAATAACACTTAGATTTATTGGACCAGTCAGCACAGCATGCCTGGTTGTATTAAAGCAGGGATATGCTGTATTTTATAAAATTGG
CAAAATTAGAGAAATATAGTTCACAATGAAATTATATTTTCTTTGTAAAGAAAGTGGCTTGAAATCTTTTTTGTTCAAAGATTAATGCCAACTCTTAAGA
TTATTCTTTCACCAACTATAGAATGTATTTTATATATCGTTCATTGTAAAAAGCCCTTAAAAATATGTGTATACTACTTTGGCTCTTGTGCATAAAAACA
AGAACACTGAAAATTGGGAATATGCACAAACTTGGCTTCTTTAACCAAGAATATTATTGGAAAATTCTCTAAAAGTTAATAGGGTAAATTCTCTATTTTT
TGTAATGTGTTCGGTGATTTCAGAAAGCTAGAAAGTGTATGTGTGGCATTTGTTTTCACTTTTTAAAACATCCCTAACTGATCGAATATATCAGTAATTT
CAGAATCAGATGCATCCTTTCATAAGAAGTGAGAGGACTCTGACAGCCATAACAGGAGTGCCACTTCATGGTGCGAAGTGAACACTGTAGTCTTGTTGTT
TTCCCAAAGAGAACTCCGTATGTTCTCTTAGGTTGAGTAACCCACTCTGAATTCTGGTTACATGTGTTTTTCTCTCCCTCCTTAAATAAAGAGAGGGGTT
AAACATGCCCTCTAAAAGTAGGTGGTTTTGAAGAGAATAAATTCATCAGATAACCTCAAGTCACATGAGAATCTTAGTCCATTTACATTGCCTTGGCTAG
TAAAAGCCATCTATGTATATGTCTTACCTCATCTCCTAAAAGGCAGAGTACAAAGTAAGCCATGTATCTCAGGAAGGTAACTTCATTTTGTCTATTTGCT
GTTGATTGTACCAAGGGATGGAAGAAGTAAATATAGCTCAGGTAGCACTTTATACTCAGGCAGATCTCAGCCCTCTACTGAGTCCCTTAGCCAAGCAGTT
TCTTTCAAAGAAGCCAGCAGGCGAAAAGCAGGGACTGCCACTGCATTTCATATCACACTGTTAAAAGTTGTGTTTTGAAATTTTATGTTTAGTTGCACAA
ATTGGGCCAAAGAAACATTGCCTTGAGGAAGATATGATTGGAAAATCAAGAGTGTAGAAGAATAAATACTGTTTTACTGTCCAAAGACATGTTTATAGTG
CTCTGTAAATGTTCCTTTCCTTTGTAGTCTCTGGCAAGATGCTTTAGGAAGATAAAAGTTTGAGGAGAACAAACAGGAATTCTGAATTAAGCACAGAGTT
GAAGTTTATACCCGTTTCACATGCTTTTCAAGAATGTCGCAATTACTAAGAAGCAGATAATGGTGTTTTTTAGAAACCTAATTGAAGTATATTCAACCAA
ATACTTTAATGTATAAAATAAATATTATACAATATACTTGTATAGCAGTTTCTGCTTCACATTTGATTTTTTCAAATTTAATATTTATATTAGAGATCTA
TATATGTATAAATATGTATTTTGTCAAATTTGTTACTTAAATATATAGAGACCAGTTTTCTCTGGAAGTTTGTTTAAATGACAGAAGCGTATATGAATTC
AAGAAAATTTAAGCTGCAAAAATGTATTTGCTATAAAATGAGAAGTCTCACTGATAGAGGTTCTTTATTGCTCATTTTTTAAAAAATGGACTCTTGAAAT
CTGTTAAAATAAAATTGTACATTTGGAGATGTTTCA
  • refseq_CD46.F1 (forward primer)
  • refseq_CD46.R1 (reverse primer)
  • Single exon skipping

Frame 0

ARATPTCPAALDAL*VGDCCVPYLDPEGTSLLG
WLSVSLLSSGEITASSAPRMEPPGRRECPFPSWR
FPGLLLAAMVLLLYSFSDACEEPPTFEAMELIG
KPKPYYEIGERVDYKCKKGYFYIPPLATHTICD
RNHTWLPVSDDACYRETCPYIRDPLNGQAVPANG
TYEFGYQMHFICNEGYYLIGEEILYCELKGSVA
IWSGKPPICEKVLCTPPPKIKNGKHTFSEVEVF
EYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSV
WSRAAPECKVVKCRFPVVENGKQISGFGKKFYY
KATVMFECDKGFYLDGSDTIVCDSNSTWDPPVP
KCLKVLPPSSTKPPALSHSVSTSSTTKSPASSAS
GYPKPEEGILDSLDVWVIAVIVIAIVVGVAVIC
VVP
YRYLQRRKKKGKADGGAEYATYQTKSTTPA
EQRG*IDSTTWFASSSFDSIKIFNSCYSVVSLS*
VQLWLS*YCNVA*M*VASFDASLKLV*IWV*TD
CLLSLK*HLDLLDQSAQHAWLY*SRDMLYFIKL
AKLEKYSSQ*NYIFFVKKVA*NLFCSKINANS*D
YSFTNYRMYFIYRSL*KALKNMCILLWLLCIKT
RTLKIGNMHKLGFFNQEYYWKIL*KLIG*ILYF
L*CVR*FQKARKCMCGICFHFLKHP*LIEYISNF
RIRCILS*EVRGL*QP*QECHFMVRSEHCSLVV
FPKRTPYVLLG*VTHSEFWLHVFFSPSLNKERG
*TCPLKVGGFEENKFIR*PQVT*ES*SIYIALAS
KSHLCICLTSSPKRQSTK*AMYLRKVTSFCLFA
VDCTKGWKK*I*LR*HFILRQISALY*VP*PSS
FFQRSQQAKSRDCHCISYHTVKSCVLKFYV*LHK
LGQRNIALRKI*LENQECRRINTVLLSKDMFIV
LCKCSFPL*SLARCFRKIKV*GEQTGILN*AQS
*SLYPFHMLFKNVAITKKQIMVFFRNLIEVYSTK
YFNV*NKYYTIYLYSSFCFTFDFFKFNIYIRDL
YMYKYVFCQICYLNI*RPVFSGSLFK*QKRI*I
QENLSCKNVFAIK*EVSLIEVLYCSFFKKWTLEI
C*NKIVHLEMF

Frame 1

LGPRPPVLQHWMLCELGIVASHIWTQKGLPCSA
GSRFLCFPPEK*QRLPRRAWSLPAAASVPFLPG
AFLGCFWRPWCCCCTPSPMPVRSHQHLKLWSSLV
NQNPTMRLVNE*IISVKKDTSIYLLLPPILFVI
GIIHGYLSQMTPVIEKHVHIYGIL*MAKQSLQM
GLTSLVIRCTLFVMRVIT*LVKKFYIVNLKDQ*Q
FGAVSPQYVKRFCVHHLQK*KMENTPLVK*KYL
SILMQ*LIVVILHLDQIHFHLLERARFIVVTIQ
CGVVLLQSVKWSNVDFQ*SKMENRYQDLEKNFTT
KQQLCLNAIRVFTSMAATQLSVTVTVLGIPQFQ
SVLKCCLHLVQNLQL*VIQCRLLPLQNLQRPVP
QDILNLRKEYLTVWMFGSLL*LLLP*LLELQ*FV
LSR
TDIFKGGRRKGKQMVELNMPLTRLNQPLQQ
SREAE*IPQPGLPVHLLTLLKSSIVVIL*FHSH
ECNCGLANIAMWLECR*HPLMLL*NLYEFGYEQI
ACFPLNNT*IYWTSQHSMPGCIKAGICCIL*NW
QN*RNIVHNEIIFSL*RKWLEIFFVQRLMPTLK
IILSPTIECILYIVHCKKPLKICVYYFGSCA*KQ
EH*KLGICTNLASLTKNIIGKFSKS**GKFSIF
CNVFGDFRKLESVCVAFVFTF*NIPN*SNISVI
SESDASFHKK*EDSDSHNRSATSWCEVNTVVLLF
SQRELRMFS*VE*PTLNSGYMCFSLPP*IKRGV
KHAL*K*VVLKRINSSDNLKSHENLSPFTLPWL
VKAIYVYVLPHLLKGRVQSKPCISGR*LHFVYLL
LIVPRDGRSKYSSGSTLYSGRSQPSTESLSQAV
SFKEASRRKAGTATAFHITLLKVVF*NFMFSCT
NWAKETLP*GRYDWKIKSVEE*ILFYCPKTCL*C
SVNVPFLCSLWQDALGR*KFEENKQEF*IKHRV
EVYTRFTCFSRMSQLLRSR*WCFLET*LKYIQP
NTLMYKINIIQYTCIAVSASHLIFSNLIFILEIY
ICINMYFVKFVT*IYRDQFSLEVCLNDRSVYEF
KKI*AAKMYLL*NEKSH**RFFIAHFLKNGLLK
SVKIKLYIWRCF

Frame 2

SGHAHLSCSTGCFVSWGLLRPISGPRRDFPARL
ALGFSAFLRRNNSVFRAAHGASRPPRVSLSFLA
LSWVASGGHGVAAVLLLRCL*GATNI*SYGAHW
*TKTLL*DW*TSRL*V*KRILLYTSSCHPYYL*S
ESYMATCLR*RLL*RNMSIYTGSFKWPSSPCKW
DLRVWLSDALYL**GLLLNW*RNSIL*T*RISS
NLER*APNM*KGFVYTTSKNKKWKTHL**SRSI*
VS*CSNL*L*SCTWTRSIFTYWREHDLLW*QFS
VESCCSRV*SGQMSISSSRKWKTDIRIWKKILL
QSNSYV*MR*GFLPRWQRHNCL*Q*QYLGSPSSK
VS*SAASI*YKTSSFESFSVDFFHYKISSVQCL
RIS*T*GRNT*QFGCLGHCCDCYCHSCWSCSNL
CCP
VQISSKEEEERESRWWS*ICHLPD*INHSSR
AERLNRFHNLVCQFIF*LY*NLQ*LLFCSFTLM
SATVA*LILQCGLNVGSIL*CFFETCMNLGMNR
LPAFP*ITLRFIGPVSTACLVVLKQGYAVFYKIG
KIREI*FTMKLYFLCKESGLKSFLFKD*CQLLR
LFFHQL*NVFYISFIVKSP*KYVYTTLALVHKN
KNTENWEYAQTWLL*PRILLENSLKVNRVNSLFF
VMCSVISES*KVYVWHLFSLFKTSLTDRIYQ*F
QNQMHPFIRSERTLTAITGVPLHGAK*TL*SCC
FPKENSVCSLRLSNPL*ILVTCVFLSLLK*REGL
NMPSKSRWF*RE*IHQITSSHMRILVHLHCLG*
*KPSMYMSYLIS*KAEYKVSHVSQEGNFILSIC
C*LYQGMEEVNIAQVALYTQADLSPLLSPLAKQF
LSKKPAGEKQGLPLHFISHC*KLCFEILCLVAQ
IGPKKHCLEEDMIGKSRV*KNKYCFTVQRHVYS
AL*MFLSFVVSGKML*EDKSLRRTNRNSELSTEL
KFIPVSHAFQECRNY*EADNGVF*KPN*SIFNQ
IL*CIK*ILYNILV*QFLLHI*FFQI*YLY*RS
IYV*ICILSNLLLKYIETSFLWKFV*MTEAYMNS
RKFKLQKCICYKMRSLTDRGSLLLIF*KMDS*N
LLK*NCTFGDVS

Sequence NM_002389

GCTCGGGCCACGCCCACCTGTCCTGCAGCACTGGATGCTTTGTGAGTTGGGGATTGTTGCGTCCCATATCTGGACCCAGAAGGGACTTCCCTGCTCGGCT
GGCTCTCGGTTTCTCTGCTTTCCTCCGGAGAAATAACAGCGTCTTCCGCGCCGCGCATGGAGCCTCCCGGCCGCCGCGAGTGTCCCTTTCCTTCCTGGCG
CTTTCCTGGGTTGCTTCTGGCGGCCATGGTGTTGCTGCTGTACTCCTTCTCCGATGCCTGTGAGGAGCCACCAACATTTGAAGCTATGGAGCTCATTGGT
AAACCAAAACCCTACTATGAGATTGGTGAACGAGTAGATTATAAGTGTAAAAAAGGATACTTCTATATACCTCCTCTTGCCACCCATACTATTTGTGATC
GGAATCATACATGGCTACCTGTCTCAGATGACGCCTGTTATAGAGAAACATGTCCATATATACGGGATCCTTTAAATGGCCAAGCAGTCCCTGCAAATGG
GACTTACGAGTTTGGTTATCAGATGCACTTTATTTGTAATGAGGGTTATTACTTAATTGGTGAAGAAATTCTATATTGTGAACTTAAAGGATCAGTAGCA
ATTTGGAGCGGTAAGCCCCCAATATGTGAAAAGGTTTTGTGTACACCACCTCCAAAAATAAAAAATGGAAAACACACCTTTAGTGAAGTAGAAGTATTTG
AGTATCTTGATGCAGTAACTTATAGTTGTGATCCTGCACCTGGACCAGATCCATTTTCACTTATTGGAGAGAGCACGATTTATTGTGGTGACAATTCAGT
GTGGAGTCGTGCTGCTCCAGAGTGTAAAGTGGTCAAATGTCGATTTCCAGTAGTCGAAAATGGAAAACAGATATCAGGATTTGGAAAAAAATTTTACTAC
AAAGCAACAGTTATGTTTGAATGCGATAAGGGTTTTTACCTCGATGGCAGCGACACAATTGTCTGTGACAGTAACAGTACTTGGGATCCCCCAGTTCCAA
AGTGTCTTAAAGTGCTGCCTCCATCTAGTACAAAACCTCCAGCTTTGAGTCATTCAGTGTCGACTTCTTCCACTACAAAATCTCCAGCGTCCAGTGCCTC
AGGTCCTAGGCCTACTTACAAGCCTCCAGTCTCAAATTATCCAGGATATCCTAAACCTGAGGAAGGAATACTTGACAGTTTGGATGTTTGGGTCATTGCT
GTGATTGTTATTGCCATAGTTGTTGGAGTTGCAGTAATTTGTGTTGTCCCGTACAGATATCTTCAAAGGAGGAAGAAGAAAGGCACATACCTAACTGATG
AGACCCACAGAGAAGTAAAATTTACTTCTCTCTGAGAAGGAGAGATGAGAGAAAGGTTTGCTTTTATCATTAAAAGGAAAGCAGATGGTGGAGCTGAATA
TGCCACTTACCAGACTAAATCAACCACTCCAGCAGAGCAGAGAGGCTGAATAGATTCCACAACCTGGTTTGCCAGTTCATCTTTTGACTCTATTAAAATC
TTCAATAGTTGTTATTCTGTAGTTTCACTCTCATGAGTGCAACTGTGGCTTAGCTAATATTGCAATGTGGCTTGAATGTAGGTAGCATCCTTTGATGCTT
CTTTGAAACTTGTATGAATTTGGGTATGAACAGATTGCCTGCTTTCCCTTAAATAACACTTAGATTTATTGGACCAGTCAGCACAGCATGCCTGGTTGTA
TTAAAGCAGGGATATGCTGTATTTTATAAAATTGGCAAAATTAGAGAAATATAGTTCACAATGAAATTATATTTTCTTTGTAAAGAAAGTGGCTTGAAAT
CTTTTTTGTTCAAAGATTAATGCCAACTCTTAAGATTATTCTTTCACCAACTATAGAATGTATTTTATATATCGTTCATTGTAAAAAGCCCTTAAAAATA
TGTGTATACTACTTTGGCTCTTGTGCATAAAAACAAGAACACTGAAAATTGGGAATATGCACAAACTTGGCTTCTTTAACCAAGAATATTATTGGAAAAT
TCTCTAAAAGTTAATAGGGTAAATTCTCTATTTTTTGTAATGTGTTCGGTGATTTCAGAAAGCTAGAAAGTGTATGTGTGGCATTTGTTTTCACTTTTTA
AAACATCCCTAACTGATCGAATATATCAGTAATTTCAGAATCAGATGCATCCTTTCATAAGAAGTGAGAGGACTCTGACAGCCATAACAGGAGTGCCACT
TCATGGTGCGAAGTGAACACTGTAGTCTTGTTGTTTTCCCAAAGAGAACTCCGTATGTTCTCTTAGGTTGAGTAACCCACTCTGAATTCTGGTTACATGT
GTTTTTCTCTCCCTCCTTAAATAAAGAGAGGGGTTAAACATGCCCTCTAAAAGTAGGTGGTTTTGAAGAGAATAAATTCATCAGATAACCTCAAGTCACA
TGAGAATCTTAGTCCATTTACATTGCCTTGGCTAGTAAAAGCCATCTATGTATATGTCTTACCTCATCTCCTAAAAGGCAGAGTACAAAGTAAGCCATGT
ATCTCAGGAAGGTAACTTCATTTTGTCTATTTGCTGTTGATTGTACCAAGGGATGGAAGAAGTAAATATAGCTCAGGTAGCACTTTATACTCAGGCAGAT
CTCAGCCCTCTACTGAGTCCCTTAGCCAAGCAGTTTCTTTCAAAGAAGCCAGCAGGCGAAAAGCAGGGACTGCCACTGCATTTCATATCACACTGTTAAA
AGTTGTGTTTTGAAATTTTATGTTTAGTTGCACAAATTGGGCCAAAGAAACATTGCCTTGAGGAAGATATGATTGGAAAATCAAGAGTGTAGAAGAATAA
ATACTGTTTTACTGTCCAAAGACATGTTTATAGTGCTCTGTAAATGTTCCTTTCCTTTGTAGTCTCTGGCAAGATGCTTTAGGAAGATAAAAGTTTGAGG
AGAACAAACAGGAATTCTGAATTAAGCACAGAGTTGAAGTTTATACCCGTTTCACATGCTTTTCAAGAATGTCGCAATTACTAAGAAGCAGATAATGGTG
TTTTTTAGAAACCTAATTGAAGTATATTCAACCAAATACTTTAATGTATAAAATAAATATTATACAATATACTTGTATAGCAGTTTCTGCTTCACATTTG
ATTTTTTCAAATTTAATATTTATATTAGAGATCTATATATGTATAAATATGTATTTTGTCAAATTTGTTACTTAAATATATAGAGACCAGTTTTCTCTGG
AAGTTTGTTTAAATGACAGAAGCGTATATGAATTCAAGAAAATTTAAGCTGCAAAAATGTATTTGCTATAAAATGAGAAGTCTCACTGATAGAGGTTCTT
TATTGCTCATTTTTTAAAAAATGGACTCTTGAAATCTGTTAAAATAAAATTGTACATTTGGAGATGTTTCA
  • refseq_CD46.F1 (forward primer)
  • refseq_CD46.R1 (reverse primer)
  • Single exon skipping

Frame 0

ARATPTCPAALDAL*VGDCCVPYLDPEGTSLLG
WLSVSLLSSGEITASSAPRMEPPGRRECPFPSWR
FPGLLLAAMVLLLYSFSDACEEPPTFEAMELIG
KPKPYYEIGERVDYKCKKGYFYIPPLATHTICD
RNHTWLPVSDDACYRETCPYIRDPLNGQAVPANG
TYEFGYQMHFICNEGYYLIGEEILYCELKGSVA
IWSGKPPICEKVLCTPPPKIKNGKHTFSEVEVF
EYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSV
WSRAAPECKVVKCRFPVVENGKQISGFGKKFYY
KATVMFECDKGFYLDGSDTIVCDSNSTWDPPVP
KCLKVLPPSSTKPPALSHSVSTSSTTKSPASSAS
GPRPTYKPPVSNYPGYPKPEEGILDSLDVWVIA
VIVIAIVVGVAVICVVPYRYLQRRKKKGTYLTD
ETHREVKFTSL*EGEMRERFAFIIKRKADGGAEY
ATYQTKSTTPAEQRG*IDSTTWFASSSFDSIKI
FNSCYSVVSLS*VQLWLS*YCNVA*M*VASFDA
SLKLV*IWV*TDCLLSLK*HLDLLDQSAQHAWLY
*SRDMLYFIKLAKLEKYSSQ*NYIFFVKKVA*N
LFCSKINANS*DYSFTNYRMYFIYRSL*KALKN
MCILLWLLCIKTRTLKIGNMHKLGFFNQEYYWKI
L*KLIG*ILYFL*CVR*FQKARKCMCGICFHFL
KHP*LIEYISNFRIRCILS*EVRGL*QP*QECH
FMVRSEHCSLVVFPKRTPYVLLG*VTHSEFWLHV
FFSPSLNKERG*TCPLKVGGFEENKFIR*PQVT
*ES*SIYIALASKSHLCICLTSSPKRQSTK*AM
YLRKVTSFCLFAVDCTKGWKK*I*LR*HFILRQI
SALY*VP*PSSFFQRSQQAKSRDCHCISYHTVK
SCVLKFYV*LHKLGQRNIALRKI*LENQECRRI
NTVLLSKDMFIVLCKCSFPL*SLARCFRKIKV*G
EQTGILN*AQS*SLYPFHMLFKNVAITKKQIMV
FFRNLIEVYSTKYFNV*NKYYTIYLYSSFCFTF
DFFKFNIYIRDLYMYKYVFCQICYLNI*RPVFSG
SLFK*QKRI*IQENLSCKNVFAIK*EVSLIEVL
YCSFFKKWTLEIC*NKIVHLEMF

Frame 1

LGPRPPVLQHWMLCELGIVASHIWTQKGLPCSA
GSRFLCFPPEK*QRLPRRAWSLPAAASVPFLPG
AFLGCFWRPWCCCCTPSPMPVRSHQHLKLWSSLV
NQNPTMRLVNE*IISVKKDTSIYLLLPPILFVI
GIIHGYLSQMTPVIEKHVHIYGIL*MAKQSLQM
GLTSLVIRCTLFVMRVIT*LVKKFYIVNLKDQ*Q
FGAVSPQYVKRFCVHHLQK*KMENTPLVK*KYL
SILMQ*LIVVILHLDQIHFHLLERARFIVVTIQ
CGVVLLQSVKWSNVDFQ*SKMENRYQDLEKNFTT
KQQLCLNAIRVFTSMAATQLSVTVTVLGIPQFQ
SVLKCCLHLVQNLQL*VIQCRLLPLQNLQRPVP
QVLGLLTSLQSQIIQDILNLRKEYLTVWMFGSLL
*LLLP*LLELQ*FVLSRTDIFKGGRRKAHT*LM
RPTEK*NLLLSEKER*EKGLLLSLKGKQMVELN
MPLTRLNQPLQQSREAE*IPQPGLPVHLLTLLKS
SIVVIL*FHSHECNCGLANIAMWLECR*HPLML
L*NLYEFGYEQIACFPLNNT*IYWTSQHSMPGC
IKAGICCIL*NWQN*RNIVHNEIIFSL*RKWLEI
FFVQRLMPTLKIILSPTIECILYIVHCKKPLKI
CVYYFGSCA*KQEH*KLGICTNLASLTKNIIGK
FSKS**GKFSIFCNVFGDFRKLESVCVAFVFTF*
NIPN*SNISVISESDASFHKK*EDSDSHNRSAT
SWCEVNTVVLLFSQRELRMFS*VE*PTLNSGYM
CFSLPP*IKRGVKHAL*K*VVLKRINSSDNLKSH
ENLSPFTLPWLVKAIYVYVLPHLLKGRVQSKPC
ISGR*LHFVYLLLIVPRDGRSKYSSGSTLYSGR
SQPSTESLSQAVSFKEASRRKAGTATAFHITLLK
VVF*NFMFSCTNWAKETLP*GRYDWKIKSVEE*
ILFYCPKTCL*CSVNVPFLCSLWQDALGR*KFE
ENKQEF*IKHRVEVYTRFTCFSRMSQLLRSR*WC
FLET*LKYIQPNTLMYKINIIQYTCIAVSASHL
IFSNLIFILEIYICINMYFVKFVT*IYRDQFSL
EVCLNDRSVYEFKKI*AAKMYLL*NEKSH**RFF
IAHFLKNGLLKSVKIKLYIWRCF

Frame 2

SGHAHLSCSTGCFVSWGLLRPISGPRRDFPARL
ALGFSAFLRRNNSVFRAAHGASRPPRVSLSFLA
LSWVASGGHGVAAVLLLRCL*GATNI*SYGAHW
*TKTLL*DW*TSRL*V*KRILLYTSSCHPYYL*S
ESYMATCLR*RLL*RNMSIYTGSFKWPSSPCKW
DLRVWLSDALYL**GLLLNW*RNSIL*T*RISS
NLER*APNM*KGFVYTTSKNKKWKTHL**SRSI*
VS*CSNL*L*SCTWTRSIFTYWREHDLLW*QFS
VESCCSRV*SGQMSISSSRKWKTDIRIWKKILL
QSNSYV*MR*GFLPRWQRHNCL*Q*QYLGSPSSK
VS*SAASI*YKTSSFESFSVDFFHYKISSVQCL
RS*AYLQASSLKLSRIS*T*GRNT*QFGCLGHC
CDCYCHSCWSCSNLCCPVQISSKEEEERHIPN**
DPQRSKIYFSLRRRDERKVCFYH*KESRWWS*I
CHLPD*INHSSRAERLNRFHNLVCQFIF*LY*N
LQ*LLFCSFTLMSATVA*LILQCGLNVGSIL*CF
FETCMNLGMNRLPAFP*ITLRFIGPVSTACLVV
LKQGYAVFYKIGKIREI*FTMKLYFLCKESGLK
SFLFKD*CQLLRLFFHQL*NVFYISFIVKSP*KY
VYTTLALVHKNKNTENWEYAQTWLL*PRILLEN
SLKVNRVNSLFFVMCSVISES*KVYVWHLFSLF
KTSLTDRIYQ*FQNQMHPFIRSERTLTAITGVPL
HGAK*TL*SCCFPKENSVCSLRLSNPL*ILVTC
VFLSLLK*REGLNMPSKSRWF*RE*IHQITSSH
MRILVHLHCLG**KPSMYMSYLIS*KAEYKVSHV
SQEGNFILSICC*LYQGMEEVNIAQVALYTQAD
LSPLLSPLAKQFLSKKPAGEKQGLPLHFISHC*
KLCFEILCLVAQIGPKKHCLEEDMIGKSRV*KNK
YCFTVQRHVYSAL*MFLSFVVSGKML*EDKSLR
RTNRNSELSTELKFIPVSHAFQECRNY*EADNG
VF*KPN*SIFNQIL*CIK*ILYNILV*QFLLHI*
FFQI*YLY*RSIYV*ICILSNLLLKYIETSFLW
KFV*MTEAYMNSRKFKLQKCICYKMRSLTDRGS
LLLIF*KMDS*NLLK*NCTFGDVS

Sequence NM_172359

GCTCGGGCCACGCCCACCTGTCCTGCAGCACTGGATGCTTTGTGAGTTGGGGATTGTTGCGTCCCATATCTGGACCCAGAAGGGACTTCCCTGCTCGGCT
GGCTCTCGGTTTCTCTGCTTTCCTCCGGAGAAATAACAGCGTCTTCCGCGCCGCGCATGGAGCCTCCCGGCCGCCGCGAGTGTCCCTTTCCTTCCTGGCG
CTTTCCTGGGTTGCTTCTGGCGGCCATGGTGTTGCTGCTGTACTCCTTCTCCGATGCCTGTGAGGAGCCACCAACATTTGAAGCTATGGAGCTCATTGGT
AAACCAAAACCCTACTATGAGATTGGTGAACGAGTAGATTATAAGTGTAAAAAAGGATACTTCTATATACCTCCTCTTGCCACCCATACTATTTGTGATC
GGAATCATACATGGCTACCTGTCTCAGATGACGCCTGTTATAGAGAAACATGTCCATATATACGGGATCCTTTAAATGGCCAAGCAGTCCCTGCAAATGG
GACTTACGAGTTTGGTTATCAGATGCACTTTATTTGTAATGAGGGTTATTACTTAATTGGTGAAGAAATTCTATATTGTGAACTTAAAGGATCAGTAGCA
ATTTGGAGCGGTAAGCCCCCAATATGTGAAAAGGTTTTGTGTACACCACCTCCAAAAATAAAAAATGGAAAACACACCTTTAGTGAAGTAGAAGTATTTG
AGTATCTTGATGCAGTAACTTATAGTTGTGATCCTGCACCTGGACCAGATCCATTTTCACTTATTGGAGAGAGCACGATTTATTGTGGTGACAATTCAGT
GTGGAGTCGTGCTGCTCCAGAGTGTAAAGTGGTCAAATGTCGATTTCCAGTAGTCGAAAATGGAAAACAGATATCAGGATTTGGAAAAAAATTTTACTAC
AAAGCAACAGTTATGTTTGAATGCGATAAGGGTTTTTACCTCGATGGCAGCGACACAATTGTCTGTGACAGTAACAGTACTTGGGATCCCCCAGTTCCAA
AGTGTCTTAAAGTGCTGCCTCCATCTAGTACAAAACCTCCAGCTTTGAGTCATTCAGTGTCGACTTCTTCCACTACAAAATCTCCAGCGTCCAGTGCCTC
AGGTCCTAGGCCTACTTACAAGCCTCCAGTCTCAAATTATCCAGGATATCCTAAACCTGAGGAAGGAATACTTGACAGTTTGGATGTTTGGGTCATTGCT
GTGATTGTTATTGCCATAGTTGTTGGAGTTGCAGTAATTTGTGTTGTCCCGTACAGATATCTTCAAAGGAGGAAGAAGAAAGGGAAAGCAGATGGTGGAG
CTGAATATGCCACTTACCAGACTAAATCAACCACTCCAGCAGAGCAGAGAGGCTGAATAGATTCCACAACCTGGTTTGCCAGTTCATCTTTTGACTCTAT
TAAAATCTTCAATAGTTGTTATTCTGTAGTTTCACTCTCATGAGTGCAACTGTGGCTTAGCTAATATTGCAATGTGGCTTGAATGTAGGTAGCATCCTTT
GATGCTTCTTTGAAACTTGTATGAATTTGGGTATGAACAGATTGCCTGCTTTCCCTTAAATAACACTTAGATTTATTGGACCAGTCAGCACAGCATGCCT
GGTTGTATTAAAGCAGGGATATGCTGTATTTTATAAAATTGGCAAAATTAGAGAAATATAGTTCACAATGAAATTATATTTTCTTTGTAAAGAAAGTGGC
TTGAAATCTTTTTTGTTCAAAGATTAATGCCAACTCTTAAGATTATTCTTTCACCAACTATAGAATGTATTTTATATATCGTTCATTGTAAAAAGCCCTT
AAAAATATGTGTATACTACTTTGGCTCTTGTGCATAAAAACAAGAACACTGAAAATTGGGAATATGCACAAACTTGGCTTCTTTAACCAAGAATATTATT
GGAAAATTCTCTAAAAGTTAATAGGGTAAATTCTCTATTTTTTGTAATGTGTTCGGTGATTTCAGAAAGCTAGAAAGTGTATGTGTGGCATTTGTTTTCA
CTTTTTAAAACATCCCTAACTGATCGAATATATCAGTAATTTCAGAATCAGATGCATCCTTTCATAAGAAGTGAGAGGACTCTGACAGCCATAACAGGAG
TGCCACTTCATGGTGCGAAGTGAACACTGTAGTCTTGTTGTTTTCCCAAAGAGAACTCCGTATGTTCTCTTAGGTTGAGTAACCCACTCTGAATTCTGGT
TACATGTGTTTTTCTCTCCCTCCTTAAATAAAGAGAGGGGTTAAACATGCCCTCTAAAAGTAGGTGGTTTTGAAGAGAATAAATTCATCAGATAACCTCA
AGTCACATGAGAATCTTAGTCCATTTACATTGCCTTGGCTAGTAAAAGCCATCTATGTATATGTCTTACCTCATCTCCTAAAAGGCAGAGTACAAAGTAA
GCCATGTATCTCAGGAAGGTAACTTCATTTTGTCTATTTGCTGTTGATTGTACCAAGGGATGGAAGAAGTAAATATAGCTCAGGTAGCACTTTATACTCA
GGCAGATCTCAGCCCTCTACTGAGTCCCTTAGCCAAGCAGTTTCTTTCAAAGAAGCCAGCAGGCGAAAAGCAGGGACTGCCACTGCATTTCATATCACAC
TGTTAAAAGTTGTGTTTTGAAATTTTATGTTTAGTTGCACAAATTGGGCCAAAGAAACATTGCCTTGAGGAAGATATGATTGGAAAATCAAGAGTGTAGA
AGAATAAATACTGTTTTACTGTCCAAAGACATGTTTATAGTGCTCTGTAAATGTTCCTTTCCTTTGTAGTCTCTGGCAAGATGCTTTAGGAAGATAAAAG
TTTGAGGAGAACAAACAGGAATTCTGAATTAAGCACAGAGTTGAAGTTTATACCCGTTTCACATGCTTTTCAAGAATGTCGCAATTACTAAGAAGCAGAT
AATGGTGTTTTTTAGAAACCTAATTGAAGTATATTCAACCAAATACTTTAATGTATAAAATAAATATTATACAATATACTTGTATAGCAGTTTCTGCTTC
ACATTTGATTTTTTCAAATTTAATATTTATATTAGAGATCTATATATGTATAAATATGTATTTTGTCAAATTTGTTACTTAAATATATAGAGACCAGTTT
TCTCTGGAAGTTTGTTTAAATGACAGAAGCGTATATGAATTCAAGAAAATTTAAGCTGCAAAAATGTATTTGCTATAAAATGAGAAGTCTCACTGATAGA
GGTTCTTTATTGCTCATTTTTTAAAAAATGGACTCTTGAAATCTGTTAAAATAAAATTGTACATTTGGAGATGTTTCA
  • refseq_CD46.F1 (forward primer)
  • refseq_CD46.R1 (reverse primer)
  • Single exon skipping

Frame 0

ARATPTCPAALDAL*VGDCCVPYLDPEGTSLLG
WLSVSLLSSGEITASSAPRMEPPGRRECPFPSWR
FPGLLLAAMVLLLYSFSDACEEPPTFEAMELIG
KPKPYYEIGERVDYKCKKGYFYIPPLATHTICD
RNHTWLPVSDDACYRETCPYIRDPLNGQAVPANG
TYEFGYQMHFICNEGYYLIGEEILYCELKGSVA
IWSGKPPICEKVLCTPPPKIKNGKHTFSEVEVF
EYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSV
WSRAAPECKVVKCRFPVVENGKQISGFGKKFYY
KATVMFECDKGFYLDGSDTIVCDSNSTWDPPVP
KCLKVLPPSSTKPPALSHSVSTSSTTKSPASSAS
GPRPTYKPPVSNYPGYPKPEEGILDSLDVWVIA
VIVIAIVVGVAVICVVPYRYLQRRKKKGKADGG
AEYATYQTKSTTPAEQRG*IDSTTWFASSSFDSI
KIFNSCYSVVSLS*VQLWLS*YCNVA*M*VASF
DASLKLV*IWV*TDCLLSLK*HLDLLDQSAQHA
WLY*SRDMLYFIKLAKLEKYSSQ*NYIFFVKKVA
*NLFCSKINANS*DYSFTNYRMYFIYRSL*KAL
KNMCILLWLLCIKTRTLKIGNMHKLGFFNQEYY
WKIL*KLIG*ILYFL*CVR*FQKARKCMCGICFH
FLKHP*LIEYISNFRIRCILS*EVRGL*QP*QE
CHFMVRSEHCSLVVFPKRTPYVLLG*VTHSEFW
LHVFFSPSLNKERG*TCPLKVGGFEENKFIR*PQ
VT*ES*SIYIALASKSHLCICLTSSPKRQSTK*
AMYLRKVTSFCLFAVDCTKGWKK*I*LR*HFIL
RQISALY*VP*PSSFFQRSQQAKSRDCHCISYHT
VKSCVLKFYV*LHKLGQRNIALRKI*LENQECR
RINTVLLSKDMFIVLCKCSFPL*SLARCFRKIK
V*GEQTGILN*AQS*SLYPFHMLFKNVAITKKQI
MVFFRNLIEVYSTKYFNV*NKYYTIYLYSSFCF
TFDFFKFNIYIRDLYMYKYVFCQICYLNI*RPV
FSGSLFK*QKRI*IQENLSCKNVFAIK*EVSLIE
VLYCSFFKKWTLEIC*NKIVHLEMF

Frame 1

LGPRPPVLQHWMLCELGIVASHIWTQKGLPCSA
GSRFLCFPPEK*QRLPRRAWSLPAAASVPFLPG
AFLGCFWRPWCCCCTPSPMPVRSHQHLKLWSSLV
NQNPTMRLVNE*IISVKKDTSIYLLLPPILFVI
GIIHGYLSQMTPVIEKHVHIYGIL*MAKQSLQM
GLTSLVIRCTLFVMRVIT*LVKKFYIVNLKDQ*Q
FGAVSPQYVKRFCVHHLQK*KMENTPLVK*KYL
SILMQ*LIVVILHLDQIHFHLLERARFIVVTIQ
CGVVLLQSVKWSNVDFQ*SKMENRYQDLEKNFTT
KQQLCLNAIRVFTSMAATQLSVTVTVLGIPQFQ
SVLKCCLHLVQNLQL*VIQCRLLPLQNLQRPVP
QVLGLLTSLQSQIIQDILNLRKEYLTVWMFGSLL
*LLLP*LLELQ*FVLSRTDIFKGGRRKGKQMVE
LNMPLTRLNQPLQQSREAE*IPQPGLPVHLLTL
LKSSIVVIL*FHSHECNCGLANIAMWLECR*HPL
MLL*NLYEFGYEQIACFPLNNT*IYWTSQHSMP
GCIKAGICCIL*NWQN*RNIVHNEIIFSL*RKW
LEIFFVQRLMPTLKIILSPTIECILYIVHCKKPL
KICVYYFGSCA*KQEH*KLGICTNLASLTKNII
GKFSKS**GKFSIFCNVFGDFRKLESVCVAFVF
TF*NIPN*SNISVISESDASFHKK*EDSDSHNRS
ATSWCEVNTVVLLFSQRELRMFS*VE*PTLNSG
YMCFSLPP*IKRGVKHAL*K*VVLKRINSSDNL
KSHENLSPFTLPWLVKAIYVYVLPHLLKGRVQSK
PCISGR*LHFVYLLLIVPRDGRSKYSSGSTLYS
GRSQPSTESLSQAVSFKEASRRKAGTATAFHIT
LLKVVF*NFMFSCTNWAKETLP*GRYDWKIKSVE
E*ILFYCPKTCL*CSVNVPFLCSLWQDALGR*K
FEENKQEF*IKHRVEVYTRFTCFSRMSQLLRSR
*WCFLET*LKYIQPNTLMYKINIIQYTCIAVSAS
HLIFSNLIFILEIYICINMYFVKFVT*IYRDQF
SLEVCLNDRSVYEFKKI*AAKMYLL*NEKSH**
RFFIAHFLKNGLLKSVKIKLYIWRCF

Frame 2

SGHAHLSCSTGCFVSWGLLRPISGPRRDFPARL
ALGFSAFLRRNNSVFRAAHGASRPPRVSLSFLA
LSWVASGGHGVAAVLLLRCL*GATNI*SYGAHW
*TKTLL*DW*TSRL*V*KRILLYTSSCHPYYL*S
ESYMATCLR*RLL*RNMSIYTGSFKWPSSPCKW
DLRVWLSDALYL**GLLLNW*RNSIL*T*RISS
NLER*APNM*KGFVYTTSKNKKWKTHL**SRSI*
VS*CSNL*L*SCTWTRSIFTYWREHDLLW*QFS
VESCCSRV*SGQMSISSSRKWKTDIRIWKKILL
QSNSYV*MR*GFLPRWQRHNCL*Q*QYLGSPSSK
VS*SAASI*YKTSSFESFSVDFFHYKISSVQCL
RS*AYLQASSLKLSRIS*T*GRNT*QFGCLGHC
CDCYCHSCWSCSNLCCPVQISSKEEEERESRWWS
*ICHLPD*INHSSRAERLNRFHNLVCQFIF*LY
*NLQ*LLFCSFTLMSATVA*LILQCGLNVGSIL
*CFFETCMNLGMNRLPAFP*ITLRFIGPVSTACL
VVLKQGYAVFYKIGKIREI*FTMKLYFLCKESG
LKSFLFKD*CQLLRLFFHQL*NVFYISFIVKSP
*KYVYTTLALVHKNKNTENWEYAQTWLL*PRILL
ENSLKVNRVNSLFFVMCSVISES*KVYVWHLFS
LFKTSLTDRIYQ*FQNQMHPFIRSERTLTAITG
VPLHGAK*TL*SCCFPKENSVCSLRLSNPL*ILV
TCVFLSLLK*REGLNMPSKSRWF*RE*IHQITS
SHMRILVHLHCLG**KPSMYMSYLIS*KAEYKV
SHVSQEGNFILSICC*LYQGMEEVNIAQVALYTQ
ADLSPLLSPLAKQFLSKKPAGEKQGLPLHFISH
C*KLCFEILCLVAQIGPKKHCLEEDMIGKSRV*
KNKYCFTVQRHVYSAL*MFLSFVVSGKML*EDKS
LRRTNRNSELSTELKFIPVSHAFQECRNY*EAD
NGVF*KPN*SIFNQIL*CIK*ILYNILV*QFLL
HI*FFQI*YLY*RSIYV*ICILSNLLLKYIETSF
LWKFV*MTEAYMNSRKFKLQKCICYKMRSLTDR
GSLLLIF*KMDS*NLLK*NCTFGDVS

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