Back to Rnomics Platform
 Open Session
×
1 warning:
  • Access restricted to public data.
    Please sign in at Rnomics Platform to access your data.
Navigation
Home
Sequences

Sequence NM_153826

GCTCGGGCCACGCCCACCTGTCCTGCAGCACTGGATGCTTTGTGAGTTGGGGATTGTTGCGTCCCATATCTGGACCCAGAAGGGACTTCCCTGCTCGGCT
GGCTCTCGGTTTCTCTGCTTTCCTCCGGAGAAATAACAGCGTCTTCCGCGCCGCGCATGGAGCCTCCCGGCCGCCGCGAGTGTCCCTTTCCTTCCTGGCG
CTTTCCTGGGTTGCTTCTGGCGGCCATGGTGTTGCTGCTGTACTCCTTCTCCGATGCCTGTGAGGAGCCACCAACATTTGAAGCTATGGAGCTCATTGGT
AAACCAAAACCCTACTATGAGATTGGTGAACGAGTAGATTATAAGTGTAAAAAAGGATACTTCTATATACCTCCTCTTGCCACCCATACTATTTGTGATC
GGAATCATACATGGCTACCTGTCTCAGATGACGCCTGTTATAGAGAAACATGTCCATATATACGGGATCCTTTAAATGGCCAAGCAGTCCCTGCAAATGG
GACTTACGAGTTTGGTTATCAGATGCACTTTATTTGTAATGAGGGTTATTACTTAATTGGTGAAGAAATTCTATATTGTGAACTTAAAGGATCAGTAGCA
ATTTGGAGCGGTAAGCCCCCAATATGTGAAAAGGTTTTGTGTACACCACCTCCAAAAATAAAAAATGGAAAACACACCTTTAGTGAAGTAGAAGTATTTG
AGTATCTTGATGCAGTAACTTATAGTTGTGATCCTGCACCTGGACCAGATCCATTTTCACTTATTGGAGAGAGCACGATTTATTGTGGTGACAATTCAGT
GTGGAGTCGTGCTGCTCCAGAGTGTAAAGTGGTCAAATGTCGATTTCCAGTAGTCGAAAATGGAAAACAGATATCAGGATTTGGAAAAAAATTTTACTAC
AAAGCAACAGTTATGTTTGAATGCGATAAGGGTTTTTACCTCGATGGCAGCGACACAATTGTCTGTGACAGTAACAGTACTTGGGATCCCCCAGTTCCAA
AGTGTCTTAAAGTGTCGACTTCTTCCACTACAAAATCTCCAGCGTCCAGTGCCTCAGGTCCTAGGCCTACTTACAAGCCTCCAGTCTCAAATTATCCAGG
ATATCCTAAACCTGAGGAAGGAATACTTGACAGTTTGGATGTTTGGGTCATTGCTGTGATTGTTATTGCCATAGTTGTTGGAGTTGCAGTAATTTGTGTT
GTCCCGTACAGATATCTTCAAAGGAGGAAGAAGAAAGGGAAAGCAGATGGTGGAGCTGAATATGCCACTTACCAGACTAAATCAACCACTCCAGCAGAGC
AGAGAGGCTGAATAGATTCCACAACCTGGTTTGCCAGTTCATCTTTTGACTCTATTAAAATCTTCAATAGTTGTTATTCTGTAGTTTCACTCTCATGAGT
GCAACTGTGGCTTAGCTAATATTGCAATGTGGCTTGAATGTAGGTAGCATCCTTTGATGCTTCTTTGAAACTTGTATGAATTTGGGTATGAACAGATTGC
CTGCTTTCCCTTAAATAACACTTAGATTTATTGGACCAGTCAGCACAGCATGCCTGGTTGTATTAAAGCAGGGATATGCTGTATTTTATAAAATTGGCAA
AATTAGAGAAATATAGTTCACAATGAAATTATATTTTCTTTGTAAAGAAAGTGGCTTGAAATCTTTTTTGTTCAAAGATTAATGCCAACTCTTAAGATTA
TTCTTTCACCAACTATAGAATGTATTTTATATATCGTTCATTGTAAAAAGCCCTTAAAAATATGTGTATACTACTTTGGCTCTTGTGCATAAAAACAAGA
ACACTGAAAATTGGGAATATGCACAAACTTGGCTTCTTTAACCAAGAATATTATTGGAAAATTCTCTAAAAGTTAATAGGGTAAATTCTCTATTTTTTGT
AATGTGTTCGGTGATTTCAGAAAGCTAGAAAGTGTATGTGTGGCATTTGTTTTCACTTTTTAAAACATCCCTAACTGATCGAATATATCAGTAATTTCAG
AATCAGATGCATCCTTTCATAAGAAGTGAGAGGACTCTGACAGCCATAACAGGAGTGCCACTTCATGGTGCGAAGTGAACACTGTAGTCTTGTTGTTTTC
CCAAAGAGAACTCCGTATGTTCTCTTAGGTTGAGTAACCCACTCTGAATTCTGGTTACATGTGTTTTTCTCTCCCTCCTTAAATAAAGAGAGGGGTTAAA
CATGCCCTCTAAAAGTAGGTGGTTTTGAAGAGAATAAATTCATCAGATAACCTCAAGTCACATGAGAATCTTAGTCCATTTACATTGCCTTGGCTAGTAA
AAGCCATCTATGTATATGTCTTACCTCATCTCCTAAAAGGCAGAGTACAAAGTAAGCCATGTATCTCAGGAAGGTAACTTCATTTTGTCTATTTGCTGTT
GATTGTACCAAGGGATGGAAGAAGTAAATATAGCTCAGGTAGCACTTTATACTCAGGCAGATCTCAGCCCTCTACTGAGTCCCTTAGCCAAGCAGTTTCT
TTCAAAGAAGCCAGCAGGCGAAAAGCAGGGACTGCCACTGCATTTCATATCACACTGTTAAAAGTTGTGTTTTGAAATTTTATGTTTAGTTGCACAAATT
GGGCCAAAGAAACATTGCCTTGAGGAAGATATGATTGGAAAATCAAGAGTGTAGAAGAATAAATACTGTTTTACTGTCCAAAGACATGTTTATAGTGCTC
TGTAAATGTTCCTTTCCTTTGTAGTCTCTGGCAAGATGCTTTAGGAAGATAAAAGTTTGAGGAGAACAAACAGGAATTCTGAATTAAGCACAGAGTTGAA
GTTTATACCCGTTTCACATGCTTTTCAAGAATGTCGCAATTACTAAGAAGCAGATAATGGTGTTTTTTAGAAACCTAATTGAAGTATATTCAACCAAATA
CTTTAATGTATAAAATAAATATTATACAATATACTTGTATAGCAGTTTCTGCTTCACATTTGATTTTTTCAAATTTAATATTTATATTAGAGATCTATAT
ATGTATAAATATGTATTTTGTCAAATTTGTTACTTAAATATATAGAGACCAGTTTTCTCTGGAAGTTTGTTTAAATGACAGAAGCGTATATGAATTCAAG
AAAATTTAAGCTGCAAAAATGTATTTGCTATAAAATGAGAAGTCTCACTGATAGAGGTTCTTTATTGCTCATTTTTTAAAAAATGGACTCTTGAAATCTG
TTAAAATAAAATTGTACATTTGGAGATGTTTCA
  • refseq_CD46.F4 (forward primer)
  • refseq_CD46.R4 (reverse primer)
  • Single exon skipping

Frame 0

ARATPTCPAALDAL*VGDCCVPYLDPEGTSLLG
WLSVSLLSSGEITASSAPRMEPPGRRECPFPSWR
FPGLLLAAMVLLLYSFSDACEEPPTFEAMELIG
KPKPYYEIGERVDYKCKKGYFYIPPLATHTICD
RNHTWLPVSDDACYRETCPYIRDPLNGQAVPANG
TYEFGYQMHFICNEGYYLIGEEILYCELKGSVA
IWSGKPPICEKVLCTPPPKIKNGKHTFSEVEVF
EYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSV
WSRAAPECKVVKCRFPVVENGKQISGFGKKFYY
KATVMFECDKGFYLDGSDTIVCDSNSTWDPPVP
KCLKVSTSSTTKSPASSASGPRPTYKPPVSNYPG
YPKPEEGILDSLDVWVIAVIVIAIVVGVAVICV
VPYRYLQRRKKKGKADGGAEYATYQTKSTTPAE
QRG*IDSTTWFASSSFDSIKIFNSCYSVVSLS*V
QLWLS*YCNVA*M*VASFDASLKLV*IWV*TDC
LLSLK*HLDLLDQSAQHAWLY*SRDMLYFIKLA
KLEKYSSQ*NYIFFVKKVA*NLFCSKINANS*DY
SFTNYRMYFIYRSL*KALKNMCILLWLLCIKTR
TLKIGNMHKLGFFNQEYYWKIL*KLIG*ILYFL
*CVR*FQKARKCMCGICFHFLKHP*LIEYISNFR
IRCILS*EVRGL*QP*QECHFMVRSEHCSLVVF
PKRTPYVLLG*VTHSEFWLHVFFSPSLNKERG*
TCPLKVGGFEENKFIR*PQVT*ES*SIYIALASK
SHLCICLTSSPKRQSTK*AMYLRKVTSFCLFAV
DCTKGWKK*I*LR*HFILRQISALY*VP*PSSF
FQRSQQAKSRDCHCISYHTVKSCVLKFYV*LHKL
GQRNIALRKI*LENQECRRINTVLLSKDMFIVL
CKCSFPL*SLARCFRKIKV*GEQTGILN*AQS*
SLYPFHMLFKNVAITKKQIMVFFRNLIEVYSTKY
FNV*NKYYTIYLYSSFCFTFDFFKFNIYIRDLY
MYKYVFCQICYLNI*RPVFSGSLFK*QKRI*IQ
ENLSCKNVFAIK*EVSLIEVLYCSFFKKWTLEIC
*NKIVHLEMF

Frame 1

LGPRPPVLQHWMLCELGIVASHIWTQKGLPCSA
GSRFLCFPPEK*QRLPRRAWSLPAAASVPFLPG
AFLGCFWRPWCCCCTPSPMPVRSHQHLKLWSSLV
NQNPTMRLVNE*IISVKKDTSIYLLLPPILFVI
GIIHGYLSQMTPVIEKHVHIYGIL*MAKQSLQM
GLTSLVIRCTLFVMRVIT*LVKKFYIVNLKDQ*Q
FGAVSPQYVKRFCVHHLQK*KMENTPLVK*KYL
SILMQ*LIVVILHLDQIHFHLLERARFIVVTIQ
CGVVLLQSVKWSNVDFQ*SKMENRYQDLEKNFTT
KQQLCLNAIRVFTSMAATQLSVTVTVLGIPQFQ
SVLKCRLLPLQNLQRPVPQVLGLLTSLQSQIIQ
DILNLRKEYLTVWMFGSLL*LLLP*LLELQ*FVL
SRTDIFKGGRRKGKQMVELNMPLTRLNQPLQQS
REAE*IPQPGLPVHLLTLLKSSIVVIL*FHSHE
CNCGLANIAMWLECR*HPLMLL*NLYEFGYEQIA
CFPLNNT*IYWTSQHSMPGCIKAGICCIL*NWQ
N*RNIVHNEIIFSL*RKWLEIFFVQRLMPTLKI
ILSPTIECILYIVHCKKPLKICVYYFGSCA*KQE
H*KLGICTNLASLTKNIIGKFSKS**GKFSIFC
NVFGDFRKLESVCVAFVFTF*NIPN*SNISVIS
ESDASFHKK*EDSDSHNRSATSWCEVNTVVLLFS
QRELRMFS*VE*PTLNSGYMCFSLPP*IKRGVK
HAL*K*VVLKRINSSDNLKSHENLSPFTLPWLV
KAIYVYVLPHLLKGRVQSKPCISGR*LHFVYLLL
IVPRDGRSKYSSGSTLYSGRSQPSTESLSQAVS
FKEASRRKAGTATAFHITLLKVVF*NFMFSCTN
WAKETLP*GRYDWKIKSVEE*ILFYCPKTCL*CS
VNVPFLCSLWQDALGR*KFEENKQEF*IKHRVE
VYTRFTCFSRMSQLLRSR*WCFLET*LKYIQPN
TLMYKINIIQYTCIAVSASHLIFSNLIFILEIYI
CINMYFVKFVT*IYRDQFSLEVCLNDRSVYEFK
KI*AAKMYLL*NEKSH**RFFIAHFLKNGLLKS
VKIKLYIWRCF

Frame 2

SGHAHLSCSTGCFVSWGLLRPISGPRRDFPARL
ALGFSAFLRRNNSVFRAAHGASRPPRVSLSFLA
LSWVASGGHGVAAVLLLRCL*GATNI*SYGAHW
*TKTLL*DW*TSRL*V*KRILLYTSSCHPYYL*S
ESYMATCLR*RLL*RNMSIYTGSFKWPSSPCKW
DLRVWLSDALYL**GLLLNW*RNSIL*T*RISS
NLER*APNM*KGFVYTTSKNKKWKTHL**SRSI*
VS*CSNL*L*SCTWTRSIFTYWREHDLLW*QFS
VESCCSRV*SGQMSISSSRKWKTDIRIWKKILL
QSNSYV*MR*GFLPRWQRHNCL*Q*QYLGSPSSK
VS*SVDFFHYKISSVQCLRS*AYLQASSLKLSR
IS*T*GRNT*QFGCLGHCCDCYCHSCWSCSNLC
CPVQISSKEEEERESRWWS*ICHLPD*INHSSRA
ERLNRFHNLVCQFIF*LY*NLQ*LLFCSFTLMS
ATVA*LILQCGLNVGSIL*CFFETCMNLGMNRL
PAFP*ITLRFIGPVSTACLVVLKQGYAVFYKIGK
IREI*FTMKLYFLCKESGLKSFLFKD*CQLLRL
FFHQL*NVFYISFIVKSP*KYVYTTLALVHKNK
NTENWEYAQTWLL*PRILLENSLKVNRVNSLFFV
MCSVISES*KVYVWHLFSLFKTSLTDRIYQ*FQ
NQMHPFIRSERTLTAITGVPLHGAK*TL*SCCF
PKENSVCSLRLSNPL*ILVTCVFLSLLK*REGLN
MPSKSRWF*RE*IHQITSSHMRILVHLHCLG**
KPSMYMSYLIS*KAEYKVSHVSQEGNFILSICC
*LYQGMEEVNIAQVALYTQADLSPLLSPLAKQFL
SKKPAGEKQGLPLHFISHC*KLCFEILCLVAQI
GPKKHCLEEDMIGKSRV*KNKYCFTVQRHVYSA
L*MFLSFVVSGKML*EDKSLRRTNRNSELSTELK
FIPVSHAFQECRNY*EADNGVF*KPN*SIFNQI
L*CIK*ILYNILV*QFLLHI*FFQI*YLY*RSI
YV*ICILSNLLLKYIETSFLWKFV*MTEAYMNSR
KFKLQKCICYKMRSLTDRGSLLLIF*KMDS*NL
LK*NCTFGDVS

Sequence NM_172358

GCTCGGGCCACGCCCACCTGTCCTGCAGCACTGGATGCTTTGTGAGTTGGGGATTGTTGCGTCCCATATCTGGACCCAGAAGGGACTTCCCTGCTCGGCT
GGCTCTCGGTTTCTCTGCTTTCCTCCGGAGAAATAACAGCGTCTTCCGCGCCGCGCATGGAGCCTCCCGGCCGCCGCGAGTGTCCCTTTCCTTCCTGGCG
CTTTCCTGGGTTGCTTCTGGCGGCCATGGTGTTGCTGCTGTACTCCTTCTCCGATGCCTGTGAGGAGCCACCAACATTTGAAGCTATGGAGCTCATTGGT
AAACCAAAACCCTACTATGAGATTGGTGAACGAGTAGATTATAAGTGTAAAAAAGGATACTTCTATATACCTCCTCTTGCCACCCATACTATTTGTGATC
GGAATCATACATGGCTACCTGTCTCAGATGACGCCTGTTATAGAGAAACATGTCCATATATACGGGATCCTTTAAATGGCCAAGCAGTCCCTGCAAATGG
GACTTACGAGTTTGGTTATCAGATGCACTTTATTTGTAATGAGGGTTATTACTTAATTGGTGAAGAAATTCTATATTGTGAACTTAAAGGATCAGTAGCA
ATTTGGAGCGGTAAGCCCCCAATATGTGAAAAGGTTTTGTGTACACCACCTCCAAAAATAAAAAATGGAAAACACACCTTTAGTGAAGTAGAAGTATTTG
AGTATCTTGATGCAGTAACTTATAGTTGTGATCCTGCACCTGGACCAGATCCATTTTCACTTATTGGAGAGAGCACGATTTATTGTGGTGACAATTCAGT
GTGGAGTCGTGCTGCTCCAGAGTGTAAAGTGGTCAAATGTCGATTTCCAGTAGTCGAAAATGGAAAACAGATATCAGGATTTGGAAAAAAATTTTACTAC
AAAGCAACAGTTATGTTTGAATGCGATAAGGGTTTTTACCTCGATGGCAGCGACACAATTGTCTGTGACAGTAACAGTACTTGGGATCCCCCAGTTCCAA
AGTGTCTTAAAGTGTCGACTTCTTCCACTACAAAATCTCCAGCGTCCAGTGCCTCAGGTCCTAGGCCTACTTACAAGCCTCCAGTCTCAAATTATCCAGG
ATATCCTAAACCTGAGGAAGGAATACTTGACAGTTTGGATGTTTGGGTCATTGCTGTGATTGTTATTGCCATAGATATCTTCAAAGGAGGAAGAAGAAAG
GGAAAGCAGATGGTGGAGCTGAATATGCCACTTACCAGACTAAATCAACCACTCCAGCAGAGCAGAGAGGCTGAATAGATTCCACAACCTGGTTTGCCAG
TTCATCTTTTGACTCTATTAAAATCTTCAATAGTTGTTATTCTGTAGTTTCACTCTCATGAGTGCAACTGTGGCTTAGCTAATATTGCAATGTGGCTTGA
ATGTAGGTAGCATCCTTTGATGCTTCTTTGAAACTTGTATGAATTTGGGTATGAACAGATTGCCTGCTTTCCCTTAAATAACACTTAGATTTATTGGACC
AGTCAGCACAGCATGCCTGGTTGTATTAAAGCAGGGATATGCTGTATTTTATAAAATTGGCAAAATTAGAGAAATATAGTTCACAATGAAATTATATTTT
CTTTGTAAAGAAAGTGGCTTGAAATCTTTTTTGTTCAAAGATTAATGCCAACTCTTAAGATTATTCTTTCACCAACTATAGAATGTATTTTATATATCGT
TCATTGTAAAAAGCCCTTAAAAATATGTGTATACTACTTTGGCTCTTGTGCATAAAAACAAGAACACTGAAAATTGGGAATATGCACAAACTTGGCTTCT
TTAACCAAGAATATTATTGGAAAATTCTCTAAAAGTTAATAGGGTAAATTCTCTATTTTTTGTAATGTGTTCGGTGATTTCAGAAAGCTAGAAAGTGTAT
GTGTGGCATTTGTTTTCACTTTTTAAAACATCCCTAACTGATCGAATATATCAGTAATTTCAGAATCAGATGCATCCTTTCATAAGAAGTGAGAGGACTC
TGACAGCCATAACAGGAGTGCCACTTCATGGTGCGAAGTGAACACTGTAGTCTTGTTGTTTTCCCAAAGAGAACTCCGTATGTTCTCTTAGGTTGAGTAA
CCCACTCTGAATTCTGGTTACATGTGTTTTTCTCTCCCTCCTTAAATAAAGAGAGGGGTTAAACATGCCCTCTAAAAGTAGGTGGTTTTGAAGAGAATAA
ATTCATCAGATAACCTCAAGTCACATGAGAATCTTAGTCCATTTACATTGCCTTGGCTAGTAAAAGCCATCTATGTATATGTCTTACCTCATCTCCTAAA
AGGCAGAGTACAAAGTAAGCCATGTATCTCAGGAAGGTAACTTCATTTTGTCTATTTGCTGTTGATTGTACCAAGGGATGGAAGAAGTAAATATAGCTCA
GGTAGCACTTTATACTCAGGCAGATCTCAGCCCTCTACTGAGTCCCTTAGCCAAGCAGTTTCTTTCAAAGAAGCCAGCAGGCGAAAAGCAGGGACTGCCA
CTGCATTTCATATCACACTGTTAAAAGTTGTGTTTTGAAATTTTATGTTTAGTTGCACAAATTGGGCCAAAGAAACATTGCCTTGAGGAAGATATGATTG
GAAAATCAAGAGTGTAGAAGAATAAATACTGTTTTACTGTCCAAAGACATGTTTATAGTGCTCTGTAAATGTTCCTTTCCTTTGTAGTCTCTGGCAAGAT
GCTTTAGGAAGATAAAAGTTTGAGGAGAACAAACAGGAATTCTGAATTAAGCACAGAGTTGAAGTTTATACCCGTTTCACATGCTTTTCAAGAATGTCGC
AATTACTAAGAAGCAGATAATGGTGTTTTTTAGAAACCTAATTGAAGTATATTCAACCAAATACTTTAATGTATAAAATAAATATTATACAATATACTTG
TATAGCAGTTTCTGCTTCACATTTGATTTTTTCAAATTTAATATTTATATTAGAGATCTATATATGTATAAATATGTATTTTGTCAAATTTGTTACTTAA
ATATATAGAGACCAGTTTTCTCTGGAAGTTTGTTTAAATGACAGAAGCGTATATGAATTCAAGAAAATTTAAGCTGCAAAAATGTATTTGCTATAAAATG
AGAAGTCTCACTGATAGAGGTTCTTTATTGCTCATTTTTTAAAAAATGGACTCTTGAAATCTGTTAAAATAAAATTGTACATTTGGAGATGTTTCA
  • refseq_CD46.F4 (forward primer)
  • refseq_CD46.R4 (reverse primer)
  • Single exon skipping

Frame 0

ARATPTCPAALDAL*VGDCCVPYLDPEGTSLLG
WLSVSLLSSGEITASSAPRMEPPGRRECPFPSWR
FPGLLLAAMVLLLYSFSDACEEPPTFEAMELIG
KPKPYYEIGERVDYKCKKGYFYIPPLATHTICD
RNHTWLPVSDDACYRETCPYIRDPLNGQAVPANG
TYEFGYQMHFICNEGYYLIGEEILYCELKGSVA
IWSGKPPICEKVLCTPPPKIKNGKHTFSEVEVF
EYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSV
WSRAAPECKVVKCRFPVVENGKQISGFGKKFYY
KATVMFECDKGFYLDGSDTIVCDSNSTWDPPVP
KCLKVSTSSTTKSPASSASGPRPTYKPPVSNYPG
YPKPEEGILDSLDVWVIAVIVIAIDIFKGGRRK
GKQMVELNMPLTRLNQPLQQSREAE*IPQPGLP
VHLLTLLKSSIVVIL*FHSHECNCGLANIAMWLE
CR*HPLMLL*NLYEFGYEQIACFPLNNT*IYWT
SQHSMPGCIKAGICCIL*NWQN*RNIVHNEIIF
SL*RKWLEIFFVQRLMPTLKIILSPTIECILYIV
HCKKPLKICVYYFGSCA*KQEH*KLGICTNLAS
LTKNIIGKFSKS**GKFSIFCNVFGDFRKLESV
CVAFVFTF*NIPN*SNISVISESDASFHKK*EDS
DSHNRSATSWCEVNTVVLLFSQRELRMFS*VE*
PTLNSGYMCFSLPP*IKRGVKHAL*K*VVLKRI
NSSDNLKSHENLSPFTLPWLVKAIYVYVLPHLLK
GRVQSKPCISGR*LHFVYLLLIVPRDGRSKYSS
GSTLYSGRSQPSTESLSQAVSFKEASRRKAGTA
TAFHITLLKVVF*NFMFSCTNWAKETLP*GRYDW
KIKSVEE*ILFYCPKTCL*CSVNVPFLCSLWQD
ALGR*KFEENKQEF*IKHRVEVYTRFTCFSRMS
QLLRSR*WCFLET*LKYIQPNTLMYKINIIQYTC
IAVSASHLIFSNLIFILEIYICINMYFVKFVT*
IYRDQFSLEVCLNDRSVYEFKKI*AAKMYLL*N
EKSH**RFFIAHFLKNGLLKSVKIKLYIWRCF

Frame 1

LGPRPPVLQHWMLCELGIVASHIWTQKGLPCSA
GSRFLCFPPEK*QRLPRRAWSLPAAASVPFLPG
AFLGCFWRPWCCCCTPSPMPVRSHQHLKLWSSLV
NQNPTMRLVNE*IISVKKDTSIYLLLPPILFVI
GIIHGYLSQMTPVIEKHVHIYGIL*MAKQSLQM
GLTSLVIRCTLFVMRVIT*LVKKFYIVNLKDQ*Q
FGAVSPQYVKRFCVHHLQK*KMENTPLVK*KYL
SILMQ*LIVVILHLDQIHFHLLERARFIVVTIQ
CGVVLLQSVKWSNVDFQ*SKMENRYQDLEKNFTT
KQQLCLNAIRVFTSMAATQLSVTVTVLGIPQFQ
SVLKCRLLPLQNLQRPVPQVLGLLTSLQSQIIQ
DILNLRKEYLTVWMFGSLL*LLLP*ISSKEEEER
ESRWWS*ICHLPD*INHSSRAERLNRFHNLVCQ
FIF*LY*NLQ*LLFCSFTLMSATVA*LILQCGL
NVGSIL*CFFETCMNLGMNRLPAFP*ITLRFIGP
VSTACLVVLKQGYAVFYKIGKIREI*FTMKLYF
LCKESGLKSFLFKD*CQLLRLFFHQL*NVFYIS
FIVKSP*KYVYTTLALVHKNKNTENWEYAQTWLL
*PRILLENSLKVNRVNSLFFVMCSVISES*KVY
VWHLFSLFKTSLTDRIYQ*FQNQMHPFIRSERT
LTAITGVPLHGAK*TL*SCCFPKENSVCSLRLSN
PL*ILVTCVFLSLLK*REGLNMPSKSRWF*RE*
IHQITSSHMRILVHLHCLG**KPSMYMSYLIS*
KAEYKVSHVSQEGNFILSICC*LYQGMEEVNIAQ
VALYTQADLSPLLSPLAKQFLSKKPAGEKQGLP
LHFISHC*KLCFEILCLVAQIGPKKHCLEEDMI
GKSRV*KNKYCFTVQRHVYSAL*MFLSFVVSGKM
L*EDKSLRRTNRNSELSTELKFIPVSHAFQECR
NY*EADNGVF*KPN*SIFNQIL*CIK*ILYNIL
V*QFLLHI*FFQI*YLY*RSIYV*ICILSNLLLK
YIETSFLWKFV*MTEAYMNSRKFKLQKCICYKM
RSLTDRGSLLLIF*KMDS*NLLK*NCTFGDVS

Frame 2

SGHAHLSCSTGCFVSWGLLRPISGPRRDFPARL
ALGFSAFLRRNNSVFRAAHGASRPPRVSLSFLA
LSWVASGGHGVAAVLLLRCL*GATNI*SYGAHW
*TKTLL*DW*TSRL*V*KRILLYTSSCHPYYL*S
ESYMATCLR*RLL*RNMSIYTGSFKWPSSPCKW
DLRVWLSDALYL**GLLLNW*RNSIL*T*RISS
NLER*APNM*KGFVYTTSKNKKWKTHL**SRSI*
VS*CSNL*L*SCTWTRSIFTYWREHDLLW*QFS
VESCCSRV*SGQMSISSSRKWKTDIRIWKKILL
QSNSYV*MR*GFLPRWQRHNCL*Q*QYLGSPSSK
VS*SVDFFHYKISSVQCLRS*AYLQASSLKLSR
IS*T*GRNT*QFGCLGHCCDCYCHRYLQRRKKK
GKADGGAEYATYQTKSTTPAEQRG*IDSTTWFAS
SSFDSIKIFNSCYSVVSLS*VQLWLS*YCNVA*
M*VASFDASLKLV*IWV*TDCLLSLK*HLDLLD
QSAQHAWLY*SRDMLYFIKLAKLEKYSSQ*NYIF
FVKKVA*NLFCSKINANS*DYSFTNYRMYFIYR
SL*KALKNMCILLWLLCIKTRTLKIGNMHKLGF
FNQEYYWKIL*KLIG*ILYFL*CVR*FQKARKCM
CGICFHFLKHP*LIEYISNFRIRCILS*EVRGL
*QP*QECHFMVRSEHCSLVVFPKRTPYVLLG*V
THSEFWLHVFFSPSLNKERG*TCPLKVGGFEENK
FIR*PQVT*ES*SIYIALASKSHLCICLTSSPK
RQSTK*AMYLRKVTSFCLFAVDCTKGWKK*I*L
R*HFILRQISALY*VP*PSSFFQRSQQAKSRDCH
CISYHTVKSCVLKFYV*LHKLGQRNIALRKI*L
ENQECRRINTVLLSKDMFIVLCKCSFPL*SLAR
CFRKIKV*GEQTGILN*AQS*SLYPFHMLFKNVA
ITKKQIMVFFRNLIEVYSTKYFNV*NKYYTIYL
YSSFCFTFDFFKFNIYIRDLYMYKYVFCQICYL
NI*RPVFSGSLFK*QKRI*IQENLSCKNVFAIK*
EVSLIEVLYCSFFKKWTLEIC*NKIVHLEMF

Sequence NM_172351

GCTCGGGCCACGCCCACCTGTCCTGCAGCACTGGATGCTTTGTGAGTTGGGGATTGTTGCGTCCCATATCTGGACCCAGAAGGGACTTCCCTGCTCGGCT
GGCTCTCGGTTTCTCTGCTTTCCTCCGGAGAAATAACAGCGTCTTCCGCGCCGCGCATGGAGCCTCCCGGCCGCCGCGAGTGTCCCTTTCCTTCCTGGCG
CTTTCCTGGGTTGCTTCTGGCGGCCATGGTGTTGCTGCTGTACTCCTTCTCCGATGCCTGTGAGGAGCCACCAACATTTGAAGCTATGGAGCTCATTGGT
AAACCAAAACCCTACTATGAGATTGGTGAACGAGTAGATTATAAGTGTAAAAAAGGATACTTCTATATACCTCCTCTTGCCACCCATACTATTTGTGATC
GGAATCATACATGGCTACCTGTCTCAGATGACGCCTGTTATAGAGAAACATGTCCATATATACGGGATCCTTTAAATGGCCAAGCAGTCCCTGCAAATGG
GACTTACGAGTTTGGTTATCAGATGCACTTTATTTGTAATGAGGGTTATTACTTAATTGGTGAAGAAATTCTATATTGTGAACTTAAAGGATCAGTAGCA
ATTTGGAGCGGTAAGCCCCCAATATGTGAAAAGGTTTTGTGTACACCACCTCCAAAAATAAAAAATGGAAAACACACCTTTAGTGAAGTAGAAGTATTTG
AGTATCTTGATGCAGTAACTTATAGTTGTGATCCTGCACCTGGACCAGATCCATTTTCACTTATTGGAGAGAGCACGATTTATTGTGGTGACAATTCAGT
GTGGAGTCGTGCTGCTCCAGAGTGTAAAGTGGTCAAATGTCGATTTCCAGTAGTCGAAAATGGAAAACAGATATCAGGATTTGGAAAAAAATTTTACTAC
AAAGCAACAGTTATGTTTGAATGCGATAAGGGTTTTTACCTCGATGGCAGCGACACAATTGTCTGTGACAGTAACAGTACTTGGGATCCCCCAGTTCCAA
AGTGTCTTAAAGTGTCGACTTCTTCCACTACAAAATCTCCAGCGTCCAGTGCCTCAGGTCCTAGGCCTACTTACAAGCCTCCAGTCTCAAATTATCCAGG
ATATCCTAAACCTGAGGAAGGAATACTTGACAGTTTGGATGTTTGGGTCATTGCTGTGATTGTTATTGCCATAGTTGTTGGAGTTGCAGTAATTTGTGTT
GTCCCGTACAGATATCTTCAAAGGAGGAAGAAGAAAGGCACATACCTAACTGATGAGACCCACAGAGAAGTAAAATTTACTTCTCTCTGAGAAGGAGAGA
TGAGAGAAAGGTTTGCTTTTATCATTAAAAGGAAAGCAGATGGTGGAGCTGAATATGCCACTTACCAGACTAAATCAACCACTCCAGCAGAGCAGAGAGG
CTGAATAGATTCCACAACCTGGTTTGCCAGTTCATCTTTTGACTCTATTAAAATCTTCAATAGTTGTTATTCTGTAGTTTCACTCTCATGAGTGCAACTG
TGGCTTAGCTAATATTGCAATGTGGCTTGAATGTAGGTAGCATCCTTTGATGCTTCTTTGAAACTTGTATGAATTTGGGTATGAACAGATTGCCTGCTTT
CCCTTAAATAACACTTAGATTTATTGGACCAGTCAGCACAGCATGCCTGGTTGTATTAAAGCAGGGATATGCTGTATTTTATAAAATTGGCAAAATTAGA
GAAATATAGTTCACAATGAAATTATATTTTCTTTGTAAAGAAAGTGGCTTGAAATCTTTTTTGTTCAAAGATTAATGCCAACTCTTAAGATTATTCTTTC
ACCAACTATAGAATGTATTTTATATATCGTTCATTGTAAAAAGCCCTTAAAAATATGTGTATACTACTTTGGCTCTTGTGCATAAAAACAAGAACACTGA
AAATTGGGAATATGCACAAACTTGGCTTCTTTAACCAAGAATATTATTGGAAAATTCTCTAAAAGTTAATAGGGTAAATTCTCTATTTTTTGTAATGTGT
TCGGTGATTTCAGAAAGCTAGAAAGTGTATGTGTGGCATTTGTTTTCACTTTTTAAAACATCCCTAACTGATCGAATATATCAGTAATTTCAGAATCAGA
TGCATCCTTTCATAAGAAGTGAGAGGACTCTGACAGCCATAACAGGAGTGCCACTTCATGGTGCGAAGTGAACACTGTAGTCTTGTTGTTTTCCCAAAGA
GAACTCCGTATGTTCTCTTAGGTTGAGTAACCCACTCTGAATTCTGGTTACATGTGTTTTTCTCTCCCTCCTTAAATAAAGAGAGGGGTTAAACATGCCC
TCTAAAAGTAGGTGGTTTTGAAGAGAATAAATTCATCAGATAACCTCAAGTCACATGAGAATCTTAGTCCATTTACATTGCCTTGGCTAGTAAAAGCCAT
CTATGTATATGTCTTACCTCATCTCCTAAAAGGCAGAGTACAAAGTAAGCCATGTATCTCAGGAAGGTAACTTCATTTTGTCTATTTGCTGTTGATTGTA
CCAAGGGATGGAAGAAGTAAATATAGCTCAGGTAGCACTTTATACTCAGGCAGATCTCAGCCCTCTACTGAGTCCCTTAGCCAAGCAGTTTCTTTCAAAG
AAGCCAGCAGGCGAAAAGCAGGGACTGCCACTGCATTTCATATCACACTGTTAAAAGTTGTGTTTTGAAATTTTATGTTTAGTTGCACAAATTGGGCCAA
AGAAACATTGCCTTGAGGAAGATATGATTGGAAAATCAAGAGTGTAGAAGAATAAATACTGTTTTACTGTCCAAAGACATGTTTATAGTGCTCTGTAAAT
GTTCCTTTCCTTTGTAGTCTCTGGCAAGATGCTTTAGGAAGATAAAAGTTTGAGGAGAACAAACAGGAATTCTGAATTAAGCACAGAGTTGAAGTTTATA
CCCGTTTCACATGCTTTTCAAGAATGTCGCAATTACTAAGAAGCAGATAATGGTGTTTTTTAGAAACCTAATTGAAGTATATTCAACCAAATACTTTAAT
GTATAAAATAAATATTATACAATATACTTGTATAGCAGTTTCTGCTTCACATTTGATTTTTTCAAATTTAATATTTATATTAGAGATCTATATATGTATA
AATATGTATTTTGTCAAATTTGTTACTTAAATATATAGAGACCAGTTTTCTCTGGAAGTTTGTTTAAATGACAGAAGCGTATATGAATTCAAGAAAATTT
AAGCTGCAAAAATGTATTTGCTATAAAATGAGAAGTCTCACTGATAGAGGTTCTTTATTGCTCATTTTTTAAAAAATGGACTCTTGAAATCTGTTAAAAT
AAAATTGTACATTTGGAGATGTTTCA
  • refseq_CD46.F4 (forward primer)
  • refseq_CD46.R4 (reverse primer)
  • Single exon skipping

Frame 0

ARATPTCPAALDAL*VGDCCVPYLDPEGTSLLG
WLSVSLLSSGEITASSAPRMEPPGRRECPFPSWR
FPGLLLAAMVLLLYSFSDACEEPPTFEAMELIG
KPKPYYEIGERVDYKCKKGYFYIPPLATHTICD
RNHTWLPVSDDACYRETCPYIRDPLNGQAVPANG
TYEFGYQMHFICNEGYYLIGEEILYCELKGSVA
IWSGKPPICEKVLCTPPPKIKNGKHTFSEVEVF
EYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSV
WSRAAPECKVVKCRFPVVENGKQISGFGKKFYY
KATVMFECDKGFYLDGSDTIVCDSNSTWDPPVP
KCLKVSTSSTTKSPASSASGPRPTYKPPVSNYPG
YPKPEEGILDSLDVWVIAVIVIAIVVGVAVICV
VPYRYLQRRKKKGTYLTDETHREVKFTSL*EGE
MRERFAFIIKRKADGGAEYATYQTKSTTPAEQRG
*IDSTTWFASSSFDSIKIFNSCYSVVSLS*VQL
WLS*YCNVA*M*VASFDASLKLV*IWV*TDCLL
SLK*HLDLLDQSAQHAWLY*SRDMLYFIKLAKLE
KYSSQ*NYIFFVKKVA*NLFCSKINANS*DYSF
TNYRMYFIYRSL*KALKNMCILLWLLCIKTRTL
KIGNMHKLGFFNQEYYWKIL*KLIG*ILYFL*CV
R*FQKARKCMCGICFHFLKHP*LIEYISNFRIR
CILS*EVRGL*QP*QECHFMVRSEHCSLVVFPK
RTPYVLLG*VTHSEFWLHVFFSPSLNKERG*TCP
LKVGGFEENKFIR*PQVT*ES*SIYIALASKSH
LCICLTSSPKRQSTK*AMYLRKVTSFCLFAVDC
TKGWKK*I*LR*HFILRQISALY*VP*PSSFFQR
SQQAKSRDCHCISYHTVKSCVLKFYV*LHKLGQ
RNIALRKI*LENQECRRINTVLLSKDMFIVLCK
CSFPL*SLARCFRKIKV*GEQTGILN*AQS*SLY
PFHMLFKNVAITKKQIMVFFRNLIEVYSTKYFN
V*NKYYTIYLYSSFCFTFDFFKFNIYIRDLYMY
KYVFCQICYLNI*RPVFSGSLFK*QKRI*IQENL
SCKNVFAIK*EVSLIEVLYCSFFKKWTLEIC*N
KIVHLEMF

Frame 1

LGPRPPVLQHWMLCELGIVASHIWTQKGLPCSA
GSRFLCFPPEK*QRLPRRAWSLPAAASVPFLPG
AFLGCFWRPWCCCCTPSPMPVRSHQHLKLWSSLV
NQNPTMRLVNE*IISVKKDTSIYLLLPPILFVI
GIIHGYLSQMTPVIEKHVHIYGIL*MAKQSLQM
GLTSLVIRCTLFVMRVIT*LVKKFYIVNLKDQ*Q
FGAVSPQYVKRFCVHHLQK*KMENTPLVK*KYL
SILMQ*LIVVILHLDQIHFHLLERARFIVVTIQ
CGVVLLQSVKWSNVDFQ*SKMENRYQDLEKNFTT
KQQLCLNAIRVFTSMAATQLSVTVTVLGIPQFQ
SVLKCRLLPLQNLQRPVPQVLGLLTSLQSQIIQ
DILNLRKEYLTVWMFGSLL*LLLP*LLELQ*FVL
SRTDIFKGGRRKAHT*LMRPTEK*NLLLSEKER
*EKGLLLSLKGKQMVELNMPLTRLNQPLQQSRE
AE*IPQPGLPVHLLTLLKSSIVVIL*FHSHECNC
GLANIAMWLECR*HPLMLL*NLYEFGYEQIACF
PLNNT*IYWTSQHSMPGCIKAGICCIL*NWQN*
RNIVHNEIIFSL*RKWLEIFFVQRLMPTLKIILS
PTIECILYIVHCKKPLKICVYYFGSCA*KQEH*
KLGICTNLASLTKNIIGKFSKS**GKFSIFCNV
FGDFRKLESVCVAFVFTF*NIPN*SNISVISESD
ASFHKK*EDSDSHNRSATSWCEVNTVVLLFSQR
ELRMFS*VE*PTLNSGYMCFSLPP*IKRGVKHA
L*K*VVLKRINSSDNLKSHENLSPFTLPWLVKAI
YVYVLPHLLKGRVQSKPCISGR*LHFVYLLLIV
PRDGRSKYSSGSTLYSGRSQPSTESLSQAVSFK
EASRRKAGTATAFHITLLKVVF*NFMFSCTNWAK
ETLP*GRYDWKIKSVEE*ILFYCPKTCL*CSVN
VPFLCSLWQDALGR*KFEENKQEF*IKHRVEVY
TRFTCFSRMSQLLRSR*WCFLET*LKYIQPNTLM
YKINIIQYTCIAVSASHLIFSNLIFILEIYICI
NMYFVKFVT*IYRDQFSLEVCLNDRSVYEFKKI
*AAKMYLL*NEKSH**RFFIAHFLKNGLLKSVKI
KLYIWRCF

Frame 2

SGHAHLSCSTGCFVSWGLLRPISGPRRDFPARL
ALGFSAFLRRNNSVFRAAHGASRPPRVSLSFLA
LSWVASGGHGVAAVLLLRCL*GATNI*SYGAHW
*TKTLL*DW*TSRL*V*KRILLYTSSCHPYYL*S
ESYMATCLR*RLL*RNMSIYTGSFKWPSSPCKW
DLRVWLSDALYL**GLLLNW*RNSIL*T*RISS
NLER*APNM*KGFVYTTSKNKKWKTHL**SRSI*
VS*CSNL*L*SCTWTRSIFTYWREHDLLW*QFS
VESCCSRV*SGQMSISSSRKWKTDIRIWKKILL
QSNSYV*MR*GFLPRWQRHNCL*Q*QYLGSPSSK
VS*SVDFFHYKISSVQCLRS*AYLQASSLKLSR
IS*T*GRNT*QFGCLGHCCDCYCHSCWSCSNLC
CPVQISSKEEEERHIPN**DPQRSKIYFSLRRRD
ERKVCFYH*KESRWWS*ICHLPD*INHSSRAER
LNRFHNLVCQFIF*LY*NLQ*LLFCSFTLMSAT
VA*LILQCGLNVGSIL*CFFETCMNLGMNRLPAF
P*ITLRFIGPVSTACLVVLKQGYAVFYKIGKIR
EI*FTMKLYFLCKESGLKSFLFKD*CQLLRLFF
HQL*NVFYISFIVKSP*KYVYTTLALVHKNKNTE
NWEYAQTWLL*PRILLENSLKVNRVNSLFFVMC
SVISES*KVYVWHLFSLFKTSLTDRIYQ*FQNQ
MHPFIRSERTLTAITGVPLHGAK*TL*SCCFPKE
NSVCSLRLSNPL*ILVTCVFLSLLK*REGLNMP
SKSRWF*RE*IHQITSSHMRILVHLHCLG**KP
SMYMSYLIS*KAEYKVSHVSQEGNFILSICC*LY
QGMEEVNIAQVALYTQADLSPLLSPLAKQFLSK
KPAGEKQGLPLHFISHC*KLCFEILCLVAQIGP
KKHCLEEDMIGKSRV*KNKYCFTVQRHVYSAL*M
FLSFVVSGKML*EDKSLRRTNRNSELSTELKFI
PVSHAFQECRNY*EADNGVF*KPN*SIFNQIL*
CIK*ILYNILV*QFLLHI*FFQI*YLY*RSIYV*
ICILSNLLLKYIETSFLWKFV*MTEAYMNSRKF
KLQKCICYKMRSLTDRGSLLLIF*KMDS*NLLK
*NCTFGDVS

Sequence NM_172356

GCTCGGGCCACGCCCACCTGTCCTGCAGCACTGGATGCTTTGTGAGTTGGGGATTGTTGCGTCCCATATCTGGACCCAGAAGGGACTTCCCTGCTCGGCT
GGCTCTCGGTTTCTCTGCTTTCCTCCGGAGAAATAACAGCGTCTTCCGCGCCGCGCATGGAGCCTCCCGGCCGCCGCGAGTGTCCCTTTCCTTCCTGGCG
CTTTCCTGGGTTGCTTCTGGCGGCCATGGTGTTGCTGCTGTACTCCTTCTCCGATGCCTGTGAGGAGCCACCAACATTTGAAGCTATGGAGCTCATTGGT
AAACCAAAACCCTACTATGAGATTGGTGAACGAGTAGATTATAAGTGTAAAAAAGGATACTTCTATATACCTCCTCTTGCCACCCATACTATTTGTGATC
GGAATCATACATGGCTACCTGTCTCAGATGACGCCTGTTATAGAGAAACATGTCCATATATACGGGATCCTTTAAATGGCCAAGCAGTCCCTGCAAATGG
GACTTACGAGTTTGGTTATCAGATGCACTTTATTTGTAATGAGGGTTATTACTTAATTGGTGAAGAAATTCTATATTGTGAACTTAAAGGATCAGTAGCA
ATTTGGAGCGGTAAGCCCCCAATATGTGAAAAGGTTTTGTGTACACCACCTCCAAAAATAAAAAATGGAAAACACACCTTTAGTGAAGTAGAAGTATTTG
AGTATCTTGATGCAGTAACTTATAGTTGTGATCCTGCACCTGGACCAGATCCATTTTCACTTATTGGAGAGAGCACGATTTATTGTGGTGACAATTCAGT
GTGGAGTCGTGCTGCTCCAGAGTGTAAAGTGGTCAAATGTCGATTTCCAGTAGTCGAAAATGGAAAACAGATATCAGGATTTGGAAAAAAATTTTACTAC
AAAGCAACAGTTATGTTTGAATGCGATAAGGGTTTTTACCTCGATGGCAGCGACACAATTGTCTGTGACAGTAACAGTACTTGGGATCCCCCAGTTCCAA
AGTGTCTTAAAGTGTCGACTTCTTCCACTACAAAATCTCCAGCGTCCAGTGCCTCAGGATATCCTAAACCTGAGGAAGGAATACTTGACAGTTTGGATGT
TTGGGTCATTGCTGTGATTGTTATTGCCATAGTTGTTGGAGTTGCAGTAATTTGTGTTGTCCCGTACAGATATCTTCAAAGGAGGAAGAAGAAAGGGAAA
GCAGATGGTGGAGCTGAATATGCCACTTACCAGACTAAATCAACCACTCCAGCAGAGCAGAGAGGCTGAATAGATTCCACAACCTGGTTTGCCAGTTCAT
CTTTTGACTCTATTAAAATCTTCAATAGTTGTTATTCTGTAGTTTCACTCTCATGAGTGCAACTGTGGCTTAGCTAATATTGCAATGTGGCTTGAATGTA
GGTAGCATCCTTTGATGCTTCTTTGAAACTTGTATGAATTTGGGTATGAACAGATTGCCTGCTTTCCCTTAAATAACACTTAGATTTATTGGACCAGTCA
GCACAGCATGCCTGGTTGTATTAAAGCAGGGATATGCTGTATTTTATAAAATTGGCAAAATTAGAGAAATATAGTTCACAATGAAATTATATTTTCTTTG
TAAAGAAAGTGGCTTGAAATCTTTTTTGTTCAAAGATTAATGCCAACTCTTAAGATTATTCTTTCACCAACTATAGAATGTATTTTATATATCGTTCATT
GTAAAAAGCCCTTAAAAATATGTGTATACTACTTTGGCTCTTGTGCATAAAAACAAGAACACTGAAAATTGGGAATATGCACAAACTTGGCTTCTTTAAC
CAAGAATATTATTGGAAAATTCTCTAAAAGTTAATAGGGTAAATTCTCTATTTTTTGTAATGTGTTCGGTGATTTCAGAAAGCTAGAAAGTGTATGTGTG
GCATTTGTTTTCACTTTTTAAAACATCCCTAACTGATCGAATATATCAGTAATTTCAGAATCAGATGCATCCTTTCATAAGAAGTGAGAGGACTCTGACA
GCCATAACAGGAGTGCCACTTCATGGTGCGAAGTGAACACTGTAGTCTTGTTGTTTTCCCAAAGAGAACTCCGTATGTTCTCTTAGGTTGAGTAACCCAC
TCTGAATTCTGGTTACATGTGTTTTTCTCTCCCTCCTTAAATAAAGAGAGGGGTTAAACATGCCCTCTAAAAGTAGGTGGTTTTGAAGAGAATAAATTCA
TCAGATAACCTCAAGTCACATGAGAATCTTAGTCCATTTACATTGCCTTGGCTAGTAAAAGCCATCTATGTATATGTCTTACCTCATCTCCTAAAAGGCA
GAGTACAAAGTAAGCCATGTATCTCAGGAAGGTAACTTCATTTTGTCTATTTGCTGTTGATTGTACCAAGGGATGGAAGAAGTAAATATAGCTCAGGTAG
CACTTTATACTCAGGCAGATCTCAGCCCTCTACTGAGTCCCTTAGCCAAGCAGTTTCTTTCAAAGAAGCCAGCAGGCGAAAAGCAGGGACTGCCACTGCA
TTTCATATCACACTGTTAAAAGTTGTGTTTTGAAATTTTATGTTTAGTTGCACAAATTGGGCCAAAGAAACATTGCCTTGAGGAAGATATGATTGGAAAA
TCAAGAGTGTAGAAGAATAAATACTGTTTTACTGTCCAAAGACATGTTTATAGTGCTCTGTAAATGTTCCTTTCCTTTGTAGTCTCTGGCAAGATGCTTT
AGGAAGATAAAAGTTTGAGGAGAACAAACAGGAATTCTGAATTAAGCACAGAGTTGAAGTTTATACCCGTTTCACATGCTTTTCAAGAATGTCGCAATTA
CTAAGAAGCAGATAATGGTGTTTTTTAGAAACCTAATTGAAGTATATTCAACCAAATACTTTAATGTATAAAATAAATATTATACAATATACTTGTATAG
CAGTTTCTGCTTCACATTTGATTTTTTCAAATTTAATATTTATATTAGAGATCTATATATGTATAAATATGTATTTTGTCAAATTTGTTACTTAAATATA
TAGAGACCAGTTTTCTCTGGAAGTTTGTTTAAATGACAGAAGCGTATATGAATTCAAGAAAATTTAAGCTGCAAAAATGTATTTGCTATAAAATGAGAAG
TCTCACTGATAGAGGTTCTTTATTGCTCATTTTTTAAAAAATGGACTCTTGAAATCTGTTAAAATAAAATTGTACATTTGGAGATGTTTCA
  • refseq_CD46.F4 (forward primer)
  • refseq_CD46.R4 (reverse primer)
  • Single exon skipping

Frame 0

ARATPTCPAALDAL*VGDCCVPYLDPEGTSLLG
WLSVSLLSSGEITASSAPRMEPPGRRECPFPSWR
FPGLLLAAMVLLLYSFSDACEEPPTFEAMELIG
KPKPYYEIGERVDYKCKKGYFYIPPLATHTICD
RNHTWLPVSDDACYRETCPYIRDPLNGQAVPANG
TYEFGYQMHFICNEGYYLIGEEILYCELKGSVA
IWSGKPPICEKVLCTPPPKIKNGKHTFSEVEVF
EYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSV
WSRAAPECKVVKCRFPVVENGKQISGFGKKFYY
KATVMFECDKGFYLDGSDTIVCDSNSTWDPPVP
KCLKVSTSSTTKSPASSASGYPKPEEGILDSLDV
WVIAVIVIAIVVGVAVICVVPYRYLQRRKKKGK
ADGGAEYATYQTKSTTPAEQRG*IDSTTWFASS
SFDSIKIFNSCYSVVSLS*VQLWLS*YCNVA*M*
VASFDASLKLV*IWV*TDCLLSLK*HLDLLDQS
AQHAWLY*SRDMLYFIKLAKLEKYSSQ*NYIFF
VKKVA*NLFCSKINANS*DYSFTNYRMYFIYRSL
*KALKNMCILLWLLCIKTRTLKIGNMHKLGFFN
QEYYWKIL*KLIG*ILYFL*CVR*FQKARKCMC
GICFHFLKHP*LIEYISNFRIRCILS*EVRGL*Q
P*QECHFMVRSEHCSLVVFPKRTPYVLLG*VTH
SEFWLHVFFSPSLNKERG*TCPLKVGGFEENKF
IR*PQVT*ES*SIYIALASKSHLCICLTSSPKRQ
STK*AMYLRKVTSFCLFAVDCTKGWKK*I*LR*
HFILRQISALY*VP*PSSFFQRSQQAKSRDCHC
ISYHTVKSCVLKFYV*LHKLGQRNIALRKI*LEN
QECRRINTVLLSKDMFIVLCKCSFPL*SLARCF
RKIKV*GEQTGILN*AQS*SLYPFHMLFKNVAI
TKKQIMVFFRNLIEVYSTKYFNV*NKYYTIYLYS
SFCFTFDFFKFNIYIRDLYMYKYVFCQICYLNI
*RPVFSGSLFK*QKRI*IQENLSCKNVFAIK*E
VSLIEVLYCSFFKKWTLEIC*NKIVHLEMF

Frame 1

LGPRPPVLQHWMLCELGIVASHIWTQKGLPCSA
GSRFLCFPPEK*QRLPRRAWSLPAAASVPFLPG
AFLGCFWRPWCCCCTPSPMPVRSHQHLKLWSSLV
NQNPTMRLVNE*IISVKKDTSIYLLLPPILFVI
GIIHGYLSQMTPVIEKHVHIYGIL*MAKQSLQM
GLTSLVIRCTLFVMRVIT*LVKKFYIVNLKDQ*Q
FGAVSPQYVKRFCVHHLQK*KMENTPLVK*KYL
SILMQ*LIVVILHLDQIHFHLLERARFIVVTIQ
CGVVLLQSVKWSNVDFQ*SKMENRYQDLEKNFTT
KQQLCLNAIRVFTSMAATQLSVTVTVLGIPQFQ
SVLKCRLLPLQNLQRPVPQDILNLRKEYLTVWM
FGSLL*LLLP*LLELQ*FVLSRTDIFKGGRRKGK
QMVELNMPLTRLNQPLQQSREAE*IPQPGLPVH
LLTLLKSSIVVIL*FHSHECNCGLANIAMWLEC
R*HPLMLL*NLYEFGYEQIACFPLNNT*IYWTSQ
HSMPGCIKAGICCIL*NWQN*RNIVHNEIIFSL
*RKWLEIFFVQRLMPTLKIILSPTIECILYIVH
CKKPLKICVYYFGSCA*KQEH*KLGICTNLASLT
KNIIGKFSKS**GKFSIFCNVFGDFRKLESVCV
AFVFTF*NIPN*SNISVISESDASFHKK*EDSD
SHNRSATSWCEVNTVVLLFSQRELRMFS*VE*PT
LNSGYMCFSLPP*IKRGVKHAL*K*VVLKRINS
SDNLKSHENLSPFTLPWLVKAIYVYVLPHLLKG
RVQSKPCISGR*LHFVYLLLIVPRDGRSKYSSGS
TLYSGRSQPSTESLSQAVSFKEASRRKAGTATA
FHITLLKVVF*NFMFSCTNWAKETLP*GRYDWK
IKSVEE*ILFYCPKTCL*CSVNVPFLCSLWQDAL
GR*KFEENKQEF*IKHRVEVYTRFTCFSRMSQL
LRSR*WCFLET*LKYIQPNTLMYKINIIQYTCI
AVSASHLIFSNLIFILEIYICINMYFVKFVT*IY
RDQFSLEVCLNDRSVYEFKKI*AAKMYLL*NEK
SH**RFFIAHFLKNGLLKSVKIKLYIWRCF

Frame 2

SGHAHLSCSTGCFVSWGLLRPISGPRRDFPARL
ALGFSAFLRRNNSVFRAAHGASRPPRVSLSFLA
LSWVASGGHGVAAVLLLRCL*GATNI*SYGAHW
*TKTLL*DW*TSRL*V*KRILLYTSSCHPYYL*S
ESYMATCLR*RLL*RNMSIYTGSFKWPSSPCKW
DLRVWLSDALYL**GLLLNW*RNSIL*T*RISS
NLER*APNM*KGFVYTTSKNKKWKTHL**SRSI*
VS*CSNL*L*SCTWTRSIFTYWREHDLLW*QFS
VESCCSRV*SGQMSISSSRKWKTDIRIWKKILL
QSNSYV*MR*GFLPRWQRHNCL*Q*QYLGSPSSK
VS*SVDFFHYKISSVQCLRIS*T*GRNT*QFGC
LGHCCDCYCHSCWSCSNLCCPVQISSKEEEERE
SRWWS*ICHLPD*INHSSRAERLNRFHNLVCQFI
F*LY*NLQ*LLFCSFTLMSATVA*LILQCGLNV
GSIL*CFFETCMNLGMNRLPAFP*ITLRFIGPV
STACLVVLKQGYAVFYKIGKIREI*FTMKLYFLC
KESGLKSFLFKD*CQLLRLFFHQL*NVFYISFI
VKSP*KYVYTTLALVHKNKNTENWEYAQTWLL*
PRILLENSLKVNRVNSLFFVMCSVISES*KVYVW
HLFSLFKTSLTDRIYQ*FQNQMHPFIRSERTLT
AITGVPLHGAK*TL*SCCFPKENSVCSLRLSNP
L*ILVTCVFLSLLK*REGLNMPSKSRWF*RE*IH
QITSSHMRILVHLHCLG**KPSMYMSYLIS*KA
EYKVSHVSQEGNFILSICC*LYQGMEEVNIAQV
ALYTQADLSPLLSPLAKQFLSKKPAGEKQGLPLH
FISHC*KLCFEILCLVAQIGPKKHCLEEDMIGK
SRV*KNKYCFTVQRHVYSAL*MFLSFVVSGKML
*EDKSLRRTNRNSELSTELKFIPVSHAFQECRNY
*EADNGVF*KPN*SIFNQIL*CIK*ILYNILV*
QFLLHI*FFQI*YLY*RSIYV*ICILSNLLLKY
IETSFLWKFV*MTEAYMNSRKFKLQKCICYKMRS
LTDRGSLLLIF*KMDS*NLLK*NCTFGDVS

Sequence NM_172355

GCTCGGGCCACGCCCACCTGTCCTGCAGCACTGGATGCTTTGTGAGTTGGGGATTGTTGCGTCCCATATCTGGACCCAGAAGGGACTTCCCTGCTCGGCT
GGCTCTCGGTTTCTCTGCTTTCCTCCGGAGAAATAACAGCGTCTTCCGCGCCGCGCATGGAGCCTCCCGGCCGCCGCGAGTGTCCCTTTCCTTCCTGGCG
CTTTCCTGGGTTGCTTCTGGCGGCCATGGTGTTGCTGCTGTACTCCTTCTCCGATGCCTGTGAGGAGCCACCAACATTTGAAGCTATGGAGCTCATTGGT
AAACCAAAACCCTACTATGAGATTGGTGAACGAGTAGATTATAAGTGTAAAAAAGGATACTTCTATATACCTCCTCTTGCCACCCATACTATTTGTGATC
GGAATCATACATGGCTACCTGTCTCAGATGACGCCTGTTATAGAGAAACATGTCCATATATACGGGATCCTTTAAATGGCCAAGCAGTCCCTGCAAATGG
GACTTACGAGTTTGGTTATCAGATGCACTTTATTTGTAATGAGGGTTATTACTTAATTGGTGAAGAAATTCTATATTGTGAACTTAAAGGATCAGTAGCA
ATTTGGAGCGGTAAGCCCCCAATATGTGAAAAGGTTTTGTGTACACCACCTCCAAAAATAAAAAATGGAAAACACACCTTTAGTGAAGTAGAAGTATTTG
AGTATCTTGATGCAGTAACTTATAGTTGTGATCCTGCACCTGGACCAGATCCATTTTCACTTATTGGAGAGAGCACGATTTATTGTGGTGACAATTCAGT
GTGGAGTCGTGCTGCTCCAGAGTGTAAAGTGGTCAAATGTCGATTTCCAGTAGTCGAAAATGGAAAACAGATATCAGGATTTGGAAAAAAATTTTACTAC
AAAGCAACAGTTATGTTTGAATGCGATAAGGGTTTTTACCTCGATGGCAGCGACACAATTGTCTGTGACAGTAACAGTACTTGGGATCCCCCAGTTCCAA
AGTGTCTTAAAGTGTCGACTTCTTCCACTACAAAATCTCCAGCGTCCAGTGCCTCAGGATATCCTAAACCTGAGGAAGGAATACTTGACAGTTTGGATGT
TTGGGTCATTGCTGTGATTGTTATTGCCATAGTTGTTGGAGTTGCAGTAATTTGTGTTGTCCCGTACAGATATCTTCAAAGGAGGAAGAAGAAAGGCACA
TACCTAACTGATGAGACCCACAGAGAAGTAAAATTTACTTCTCTCTGAGAAGGAGAGATGAGAGAAAGGTTTGCTTTTATCATTAAAAGGAAAGCAGATG
GTGGAGCTGAATATGCCACTTACCAGACTAAATCAACCACTCCAGCAGAGCAGAGAGGCTGAATAGATTCCACAACCTGGTTTGCCAGTTCATCTTTTGA
CTCTATTAAAATCTTCAATAGTTGTTATTCTGTAGTTTCACTCTCATGAGTGCAACTGTGGCTTAGCTAATATTGCAATGTGGCTTGAATGTAGGTAGCA
TCCTTTGATGCTTCTTTGAAACTTGTATGAATTTGGGTATGAACAGATTGCCTGCTTTCCCTTAAATAACACTTAGATTTATTGGACCAGTCAGCACAGC
ATGCCTGGTTGTATTAAAGCAGGGATATGCTGTATTTTATAAAATTGGCAAAATTAGAGAAATATAGTTCACAATGAAATTATATTTTCTTTGTAAAGAA
AGTGGCTTGAAATCTTTTTTGTTCAAAGATTAATGCCAACTCTTAAGATTATTCTTTCACCAACTATAGAATGTATTTTATATATCGTTCATTGTAAAAA
GCCCTTAAAAATATGTGTATACTACTTTGGCTCTTGTGCATAAAAACAAGAACACTGAAAATTGGGAATATGCACAAACTTGGCTTCTTTAACCAAGAAT
ATTATTGGAAAATTCTCTAAAAGTTAATAGGGTAAATTCTCTATTTTTTGTAATGTGTTCGGTGATTTCAGAAAGCTAGAAAGTGTATGTGTGGCATTTG
TTTTCACTTTTTAAAACATCCCTAACTGATCGAATATATCAGTAATTTCAGAATCAGATGCATCCTTTCATAAGAAGTGAGAGGACTCTGACAGCCATAA
CAGGAGTGCCACTTCATGGTGCGAAGTGAACACTGTAGTCTTGTTGTTTTCCCAAAGAGAACTCCGTATGTTCTCTTAGGTTGAGTAACCCACTCTGAAT
TCTGGTTACATGTGTTTTTCTCTCCCTCCTTAAATAAAGAGAGGGGTTAAACATGCCCTCTAAAAGTAGGTGGTTTTGAAGAGAATAAATTCATCAGATA
ACCTCAAGTCACATGAGAATCTTAGTCCATTTACATTGCCTTGGCTAGTAAAAGCCATCTATGTATATGTCTTACCTCATCTCCTAAAAGGCAGAGTACA
AAGTAAGCCATGTATCTCAGGAAGGTAACTTCATTTTGTCTATTTGCTGTTGATTGTACCAAGGGATGGAAGAAGTAAATATAGCTCAGGTAGCACTTTA
TACTCAGGCAGATCTCAGCCCTCTACTGAGTCCCTTAGCCAAGCAGTTTCTTTCAAAGAAGCCAGCAGGCGAAAAGCAGGGACTGCCACTGCATTTCATA
TCACACTGTTAAAAGTTGTGTTTTGAAATTTTATGTTTAGTTGCACAAATTGGGCCAAAGAAACATTGCCTTGAGGAAGATATGATTGGAAAATCAAGAG
TGTAGAAGAATAAATACTGTTTTACTGTCCAAAGACATGTTTATAGTGCTCTGTAAATGTTCCTTTCCTTTGTAGTCTCTGGCAAGATGCTTTAGGAAGA
TAAAAGTTTGAGGAGAACAAACAGGAATTCTGAATTAAGCACAGAGTTGAAGTTTATACCCGTTTCACATGCTTTTCAAGAATGTCGCAATTACTAAGAA
GCAGATAATGGTGTTTTTTAGAAACCTAATTGAAGTATATTCAACCAAATACTTTAATGTATAAAATAAATATTATACAATATACTTGTATAGCAGTTTC
TGCTTCACATTTGATTTTTTCAAATTTAATATTTATATTAGAGATCTATATATGTATAAATATGTATTTTGTCAAATTTGTTACTTAAATATATAGAGAC
CAGTTTTCTCTGGAAGTTTGTTTAAATGACAGAAGCGTATATGAATTCAAGAAAATTTAAGCTGCAAAAATGTATTTGCTATAAAATGAGAAGTCTCACT
GATAGAGGTTCTTTATTGCTCATTTTTTAAAAAATGGACTCTTGAAATCTGTTAAAATAAAATTGTACATTTGGAGATGTTTCA
  • refseq_CD46.F4 (forward primer)
  • refseq_CD46.R4 (reverse primer)
  • Single exon skipping

Frame 0

ARATPTCPAALDAL*VGDCCVPYLDPEGTSLLG
WLSVSLLSSGEITASSAPRMEPPGRRECPFPSWR
FPGLLLAAMVLLLYSFSDACEEPPTFEAMELIG
KPKPYYEIGERVDYKCKKGYFYIPPLATHTICD
RNHTWLPVSDDACYRETCPYIRDPLNGQAVPANG
TYEFGYQMHFICNEGYYLIGEEILYCELKGSVA
IWSGKPPICEKVLCTPPPKIKNGKHTFSEVEVF
EYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSV
WSRAAPECKVVKCRFPVVENGKQISGFGKKFYY
KATVMFECDKGFYLDGSDTIVCDSNSTWDPPVP
KCLKVSTSSTTKSPASSASGYPKPEEGILDSLDV
WVIAVIVIAIVVGVAVICVVPYRYLQRRKKKGT
YLTDETHREVKFTSL*EGEMRERFAFIIKRKAD
GGAEYATYQTKSTTPAEQRG*IDSTTWFASSSFD
SIKIFNSCYSVVSLS*VQLWLS*YCNVA*M*VA
SFDASLKLV*IWV*TDCLLSLK*HLDLLDQSAQ
HAWLY*SRDMLYFIKLAKLEKYSSQ*NYIFFVKK
VA*NLFCSKINANS*DYSFTNYRMYFIYRSL*K
ALKNMCILLWLLCIKTRTLKIGNMHKLGFFNQE
YYWKIL*KLIG*ILYFL*CVR*FQKARKCMCGIC
FHFLKHP*LIEYISNFRIRCILS*EVRGL*QP*
QECHFMVRSEHCSLVVFPKRTPYVLLG*VTHSE
FWLHVFFSPSLNKERG*TCPLKVGGFEENKFIR*
PQVT*ES*SIYIALASKSHLCICLTSSPKRQST
K*AMYLRKVTSFCLFAVDCTKGWKK*I*LR*HF
ILRQISALY*VP*PSSFFQRSQQAKSRDCHCISY
HTVKSCVLKFYV*LHKLGQRNIALRKI*LENQE
CRRINTVLLSKDMFIVLCKCSFPL*SLARCFRK
IKV*GEQTGILN*AQS*SLYPFHMLFKNVAITKK
QIMVFFRNLIEVYSTKYFNV*NKYYTIYLYSSF
CFTFDFFKFNIYIRDLYMYKYVFCQICYLNI*R
PVFSGSLFK*QKRI*IQENLSCKNVFAIK*EVSL
IEVLYCSFFKKWTLEIC*NKIVHLEMF

Frame 1

LGPRPPVLQHWMLCELGIVASHIWTQKGLPCSA
GSRFLCFPPEK*QRLPRRAWSLPAAASVPFLPG
AFLGCFWRPWCCCCTPSPMPVRSHQHLKLWSSLV
NQNPTMRLVNE*IISVKKDTSIYLLLPPILFVI
GIIHGYLSQMTPVIEKHVHIYGIL*MAKQSLQM
GLTSLVIRCTLFVMRVIT*LVKKFYIVNLKDQ*Q
FGAVSPQYVKRFCVHHLQK*KMENTPLVK*KYL
SILMQ*LIVVILHLDQIHFHLLERARFIVVTIQ
CGVVLLQSVKWSNVDFQ*SKMENRYQDLEKNFTT
KQQLCLNAIRVFTSMAATQLSVTVTVLGIPQFQ
SVLKCRLLPLQNLQRPVPQDILNLRKEYLTVWM
FGSLL*LLLP*LLELQ*FVLSRTDIFKGGRRKAH
T*LMRPTEK*NLLLSEKER*EKGLLLSLKGKQM
VELNMPLTRLNQPLQQSREAE*IPQPGLPVHLL
TLLKSSIVVIL*FHSHECNCGLANIAMWLECR*H
PLMLL*NLYEFGYEQIACFPLNNT*IYWTSQHS
MPGCIKAGICCIL*NWQN*RNIVHNEIIFSL*R
KWLEIFFVQRLMPTLKIILSPTIECILYIVHCKK
PLKICVYYFGSCA*KQEH*KLGICTNLASLTKN
IIGKFSKS**GKFSIFCNVFGDFRKLESVCVAF
VFTF*NIPN*SNISVISESDASFHKK*EDSDSHN
RSATSWCEVNTVVLLFSQRELRMFS*VE*PTLN
SGYMCFSLPP*IKRGVKHAL*K*VVLKRINSSD
NLKSHENLSPFTLPWLVKAIYVYVLPHLLKGRVQ
SKPCISGR*LHFVYLLLIVPRDGRSKYSSGSTL
YSGRSQPSTESLSQAVSFKEASRRKAGTATAFH
ITLLKVVF*NFMFSCTNWAKETLP*GRYDWKIKS
VEE*ILFYCPKTCL*CSVNVPFLCSLWQDALGR
*KFEENKQEF*IKHRVEVYTRFTCFSRMSQLLR
SR*WCFLET*LKYIQPNTLMYKINIIQYTCIAVS
ASHLIFSNLIFILEIYICINMYFVKFVT*IYRD
QFSLEVCLNDRSVYEFKKI*AAKMYLL*NEKSH
**RFFIAHFLKNGLLKSVKIKLYIWRCF

Frame 2

SGHAHLSCSTGCFVSWGLLRPISGPRRDFPARL
ALGFSAFLRRNNSVFRAAHGASRPPRVSLSFLA
LSWVASGGHGVAAVLLLRCL*GATNI*SYGAHW
*TKTLL*DW*TSRL*V*KRILLYTSSCHPYYL*S
ESYMATCLR*RLL*RNMSIYTGSFKWPSSPCKW
DLRVWLSDALYL**GLLLNW*RNSIL*T*RISS
NLER*APNM*KGFVYTTSKNKKWKTHL**SRSI*
VS*CSNL*L*SCTWTRSIFTYWREHDLLW*QFS
VESCCSRV*SGQMSISSSRKWKTDIRIWKKILL
QSNSYV*MR*GFLPRWQRHNCL*Q*QYLGSPSSK
VS*SVDFFHYKISSVQCLRIS*T*GRNT*QFGC
LGHCCDCYCHSCWSCSNLCCPVQISSKEEEERH
IPN**DPQRSKIYFSLRRRDERKVCFYH*KESRW
WS*ICHLPD*INHSSRAERLNRFHNLVCQFIF*
LY*NLQ*LLFCSFTLMSATVA*LILQCGLNVGS
IL*CFFETCMNLGMNRLPAFP*ITLRFIGPVSTA
CLVVLKQGYAVFYKIGKIREI*FTMKLYFLCKE
SGLKSFLFKD*CQLLRLFFHQL*NVFYISFIVK
SP*KYVYTTLALVHKNKNTENWEYAQTWLL*PRI
LLENSLKVNRVNSLFFVMCSVISES*KVYVWHL
FSLFKTSLTDRIYQ*FQNQMHPFIRSERTLTAI
TGVPLHGAK*TL*SCCFPKENSVCSLRLSNPL*I
LVTCVFLSLLK*REGLNMPSKSRWF*RE*IHQI
TSSHMRILVHLHCLG**KPSMYMSYLIS*KAEY
KVSHVSQEGNFILSICC*LYQGMEEVNIAQVALY
TQADLSPLLSPLAKQFLSKKPAGEKQGLPLHFI
SHC*KLCFEILCLVAQIGPKKHCLEEDMIGKSR
V*KNKYCFTVQRHVYSAL*MFLSFVVSGKML*ED
KSLRRTNRNSELSTELKFIPVSHAFQECRNY*E
ADNGVF*KPN*SIFNQIL*CIK*ILYNILV*QF
LLHI*FFQI*YLY*RSIYV*ICILSNLLLKYIET
SFLWKFV*MTEAYMNSRKFKLQKCICYKMRSLT
DRGSLLLIF*KMDS*NLLK*NCTFGDVS

Sequence NM_172354

GCTCGGGCCACGCCCACCTGTCCTGCAGCACTGGATGCTTTGTGAGTTGGGGATTGTTGCGTCCCATATCTGGACCCAGAAGGGACTTCCCTGCTCGGCT
GGCTCTCGGTTTCTCTGCTTTCCTCCGGAGAAATAACAGCGTCTTCCGCGCCGCGCATGGAGCCTCCCGGCCGCCGCGAGTGTCCCTTTCCTTCCTGGCG
CTTTCCTGGGTTGCTTCTGGCGGCCATGGTGTTGCTGCTGTACTCCTTCTCCGATGCCTGTGAGGAGCCACCAACATTTGAAGCTATGGAGCTCATTGGT
AAACCAAAACCCTACTATGAGATTGGTGAACGAGTAGATTATAAGTGTAAAAAAGGATACTTCTATATACCTCCTCTTGCCACCCATACTATTTGTGATC
GGAATCATACATGGCTACCTGTCTCAGATGACGCCTGTTATAGAGAAACATGTCCATATATACGGGATCCTTTAAATGGCCAAGCAGTCCCTGCAAATGG
GACTTACGAGTTTGGTTATCAGATGCACTTTATTTGTAATGAGGGTTATTACTTAATTGGTGAAGAAATTCTATATTGTGAACTTAAAGGATCAGTAGCA
ATTTGGAGCGGTAAGCCCCCAATATGTGAAAAGGTTTTGTGTACACCACCTCCAAAAATAAAAAATGGAAAACACACCTTTAGTGAAGTAGAAGTATTTG
AGTATCTTGATGCAGTAACTTATAGTTGTGATCCTGCACCTGGACCAGATCCATTTTCACTTATTGGAGAGAGCACGATTTATTGTGGTGACAATTCAGT
GTGGAGTCGTGCTGCTCCAGAGTGTAAAGTGGTCAAATGTCGATTTCCAGTAGTCGAAAATGGAAAACAGATATCAGGATTTGGAAAAAAATTTTACTAC
AAAGCAACAGTTATGTTTGAATGCGATAAGGGTTTTTACCTCGATGGCAGCGACACAATTGTCTGTGACAGTAACAGTACTTGGGATCCCCCAGTTCCAA
AGTGTCTTAAAGTGCTGCCTCCATCTAGTACAAAACCTCCAGCTTTGAGTCATTCAGTGTCGACTTCTTCCACTACAAAATCTCCAGCGTCCAGTGCCTC
AGGATATCCTAAACCTGAGGAAGGAATACTTGACAGTTTGGATGTTTGGGTCATTGCTGTGATTGTTATTGCCATAGTTGTTGGAGTTGCAGTAATTTGT
GTTGTCCCGTACAGATATCTTCAAAGGAGGAAGAAGAAAGGCACATACCTAACTGATGAGACCCACAGAGAAGTAAAATTTACTTCTCTCTGAGAAGGAG
AGATGAGAGAAAGGTTTGCTTTTATCATTAAAAGGAAAGCAGATGGTGGAGCTGAATATGCCACTTACCAGACTAAATCAACCACTCCAGCAGAGCAGAG
AGGCTGAATAGATTCCACAACCTGGTTTGCCAGTTCATCTTTTGACTCTATTAAAATCTTCAATAGTTGTTATTCTGTAGTTTCACTCTCATGAGTGCAA
CTGTGGCTTAGCTAATATTGCAATGTGGCTTGAATGTAGGTAGCATCCTTTGATGCTTCTTTGAAACTTGTATGAATTTGGGTATGAACAGATTGCCTGC
TTTCCCTTAAATAACACTTAGATTTATTGGACCAGTCAGCACAGCATGCCTGGTTGTATTAAAGCAGGGATATGCTGTATTTTATAAAATTGGCAAAATT
AGAGAAATATAGTTCACAATGAAATTATATTTTCTTTGTAAAGAAAGTGGCTTGAAATCTTTTTTGTTCAAAGATTAATGCCAACTCTTAAGATTATTCT
TTCACCAACTATAGAATGTATTTTATATATCGTTCATTGTAAAAAGCCCTTAAAAATATGTGTATACTACTTTGGCTCTTGTGCATAAAAACAAGAACAC
TGAAAATTGGGAATATGCACAAACTTGGCTTCTTTAACCAAGAATATTATTGGAAAATTCTCTAAAAGTTAATAGGGTAAATTCTCTATTTTTTGTAATG
TGTTCGGTGATTTCAGAAAGCTAGAAAGTGTATGTGTGGCATTTGTTTTCACTTTTTAAAACATCCCTAACTGATCGAATATATCAGTAATTTCAGAATC
AGATGCATCCTTTCATAAGAAGTGAGAGGACTCTGACAGCCATAACAGGAGTGCCACTTCATGGTGCGAAGTGAACACTGTAGTCTTGTTGTTTTCCCAA
AGAGAACTCCGTATGTTCTCTTAGGTTGAGTAACCCACTCTGAATTCTGGTTACATGTGTTTTTCTCTCCCTCCTTAAATAAAGAGAGGGGTTAAACATG
CCCTCTAAAAGTAGGTGGTTTTGAAGAGAATAAATTCATCAGATAACCTCAAGTCACATGAGAATCTTAGTCCATTTACATTGCCTTGGCTAGTAAAAGC
CATCTATGTATATGTCTTACCTCATCTCCTAAAAGGCAGAGTACAAAGTAAGCCATGTATCTCAGGAAGGTAACTTCATTTTGTCTATTTGCTGTTGATT
GTACCAAGGGATGGAAGAAGTAAATATAGCTCAGGTAGCACTTTATACTCAGGCAGATCTCAGCCCTCTACTGAGTCCCTTAGCCAAGCAGTTTCTTTCA
AAGAAGCCAGCAGGCGAAAAGCAGGGACTGCCACTGCATTTCATATCACACTGTTAAAAGTTGTGTTTTGAAATTTTATGTTTAGTTGCACAAATTGGGC
CAAAGAAACATTGCCTTGAGGAAGATATGATTGGAAAATCAAGAGTGTAGAAGAATAAATACTGTTTTACTGTCCAAAGACATGTTTATAGTGCTCTGTA
AATGTTCCTTTCCTTTGTAGTCTCTGGCAAGATGCTTTAGGAAGATAAAAGTTTGAGGAGAACAAACAGGAATTCTGAATTAAGCACAGAGTTGAAGTTT
ATACCCGTTTCACATGCTTTTCAAGAATGTCGCAATTACTAAGAAGCAGATAATGGTGTTTTTTAGAAACCTAATTGAAGTATATTCAACCAAATACTTT
AATGTATAAAATAAATATTATACAATATACTTGTATAGCAGTTTCTGCTTCACATTTGATTTTTTCAAATTTAATATTTATATTAGAGATCTATATATGT
ATAAATATGTATTTTGTCAAATTTGTTACTTAAATATATAGAGACCAGTTTTCTCTGGAAGTTTGTTTAAATGACAGAAGCGTATATGAATTCAAGAAAA
TTTAAGCTGCAAAAATGTATTTGCTATAAAATGAGAAGTCTCACTGATAGAGGTTCTTTATTGCTCATTTTTTAAAAAATGGACTCTTGAAATCTGTTAA
AATAAAATTGTACATTTGGAGATGTTTCA
  • refseq_CD46.F4 (forward primer)
  • refseq_CD46.R4 (reverse primer)
  • Single exon skipping

Frame 0

ARATPTCPAALDAL*VGDCCVPYLDPEGTSLLG
WLSVSLLSSGEITASSAPRMEPPGRRECPFPSWR
FPGLLLAAMVLLLYSFSDACEEPPTFEAMELIG
KPKPYYEIGERVDYKCKKGYFYIPPLATHTICD
RNHTWLPVSDDACYRETCPYIRDPLNGQAVPANG
TYEFGYQMHFICNEGYYLIGEEILYCELKGSVA
IWSGKPPICEKVLCTPPPKIKNGKHTFSEVEVF
EYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSV
WSRAAPECKVVKCRFPVVENGKQISGFGKKFYY
KATVMFECDKGFYLDGSDTIVCDSNSTWDPPVP
KCLKVLPPSSTKPPALSHSVSTSSTTKSPASSAS
GYPKPEEGILDSLDVWVIAVIVIAIVVGVAVIC
VVPYRYLQRRKKKGTYLTDETHREVKFTSL*EG
EMRERFAFIIKRKADGGAEYATYQTKSTTPAEQR
G*IDSTTWFASSSFDSIKIFNSCYSVVSLS*VQ
LWLS*YCNVA*M*VASFDASLKLV*IWV*TDCL
LSLK*HLDLLDQSAQHAWLY*SRDMLYFIKLAKL
EKYSSQ*NYIFFVKKVA*NLFCSKINANS*DYS
FTNYRMYFIYRSL*KALKNMCILLWLLCIKTRT
LKIGNMHKLGFFNQEYYWKIL*KLIG*ILYFL*C
VR*FQKARKCMCGICFHFLKHP*LIEYISNFRI
RCILS*EVRGL*QP*QECHFMVRSEHCSLVVFP
KRTPYVLLG*VTHSEFWLHVFFSPSLNKERG*TC
PLKVGGFEENKFIR*PQVT*ES*SIYIALASKS
HLCICLTSSPKRQSTK*AMYLRKVTSFCLFAVD
CTKGWKK*I*LR*HFILRQISALY*VP*PSSFFQ
RSQQAKSRDCHCISYHTVKSCVLKFYV*LHKLG
QRNIALRKI*LENQECRRINTVLLSKDMFIVLC
KCSFPL*SLARCFRKIKV*GEQTGILN*AQS*SL
YPFHMLFKNVAITKKQIMVFFRNLIEVYSTKYF
NV*NKYYTIYLYSSFCFTFDFFKFNIYIRDLYM
YKYVFCQICYLNI*RPVFSGSLFK*QKRI*IQEN
LSCKNVFAIK*EVSLIEVLYCSFFKKWTLEIC*
NKIVHLEMF

Frame 1

LGPRPPVLQHWMLCELGIVASHIWTQKGLPCSA
GSRFLCFPPEK*QRLPRRAWSLPAAASVPFLPG
AFLGCFWRPWCCCCTPSPMPVRSHQHLKLWSSLV
NQNPTMRLVNE*IISVKKDTSIYLLLPPILFVI
GIIHGYLSQMTPVIEKHVHIYGIL*MAKQSLQM
GLTSLVIRCTLFVMRVIT*LVKKFYIVNLKDQ*Q
FGAVSPQYVKRFCVHHLQK*KMENTPLVK*KYL
SILMQ*LIVVILHLDQIHFHLLERARFIVVTIQ
CGVVLLQSVKWSNVDFQ*SKMENRYQDLEKNFTT
KQQLCLNAIRVFTSMAATQLSVTVTVLGIPQFQ
SVLKCCLHLVQNLQL*VIQCRLLPLQNLQRPVP
QDILNLRKEYLTVWMFGSLL*LLLP*LLELQ*FV
LSRTDIFKGGRRKAHT*LMRPTEK*NLLLSEKE
R*EKGLLLSLKGKQMVELNMPLTRLNQPLQQSR
EAE*IPQPGLPVHLLTLLKSSIVVIL*FHSHECN
CGLANIAMWLECR*HPLMLL*NLYEFGYEQIAC
FPLNNT*IYWTSQHSMPGCIKAGICCIL*NWQN
*RNIVHNEIIFSL*RKWLEIFFVQRLMPTLKIIL
SPTIECILYIVHCKKPLKICVYYFGSCA*KQEH
*KLGICTNLASLTKNIIGKFSKS**GKFSIFCN
VFGDFRKLESVCVAFVFTF*NIPN*SNISVISES
DASFHKK*EDSDSHNRSATSWCEVNTVVLLFSQ
RELRMFS*VE*PTLNSGYMCFSLPP*IKRGVKH
AL*K*VVLKRINSSDNLKSHENLSPFTLPWLVKA
IYVYVLPHLLKGRVQSKPCISGR*LHFVYLLLI
VPRDGRSKYSSGSTLYSGRSQPSTESLSQAVSF
KEASRRKAGTATAFHITLLKVVF*NFMFSCTNWA
KETLP*GRYDWKIKSVEE*ILFYCPKTCL*CSV
NVPFLCSLWQDALGR*KFEENKQEF*IKHRVEV
YTRFTCFSRMSQLLRSR*WCFLET*LKYIQPNTL
MYKINIIQYTCIAVSASHLIFSNLIFILEIYIC
INMYFVKFVT*IYRDQFSLEVCLNDRSVYEFKK
I*AAKMYLL*NEKSH**RFFIAHFLKNGLLKSVK
IKLYIWRCF

Frame 2

SGHAHLSCSTGCFVSWGLLRPISGPRRDFPARL
ALGFSAFLRRNNSVFRAAHGASRPPRVSLSFLA
LSWVASGGHGVAAVLLLRCL*GATNI*SYGAHW
*TKTLL*DW*TSRL*V*KRILLYTSSCHPYYL*S
ESYMATCLR*RLL*RNMSIYTGSFKWPSSPCKW
DLRVWLSDALYL**GLLLNW*RNSIL*T*RISS
NLER*APNM*KGFVYTTSKNKKWKTHL**SRSI*
VS*CSNL*L*SCTWTRSIFTYWREHDLLW*QFS
VESCCSRV*SGQMSISSSRKWKTDIRIWKKILL
QSNSYV*MR*GFLPRWQRHNCL*Q*QYLGSPSSK
VS*SAASI*YKTSSFESFSVDFFHYKISSVQCL
RIS*T*GRNT*QFGCLGHCCDCYCHSCWSCSNL
CCPVQISSKEEEERHIPN**DPQRSKIYFSLRRR
DERKVCFYH*KESRWWS*ICHLPD*INHSSRAE
RLNRFHNLVCQFIF*LY*NLQ*LLFCSFTLMSA
TVA*LILQCGLNVGSIL*CFFETCMNLGMNRLPA
FP*ITLRFIGPVSTACLVVLKQGYAVFYKIGKI
REI*FTMKLYFLCKESGLKSFLFKD*CQLLRLF
FHQL*NVFYISFIVKSP*KYVYTTLALVHKNKNT
ENWEYAQTWLL*PRILLENSLKVNRVNSLFFVM
CSVISES*KVYVWHLFSLFKTSLTDRIYQ*FQN
QMHPFIRSERTLTAITGVPLHGAK*TL*SCCFPK
ENSVCSLRLSNPL*ILVTCVFLSLLK*REGLNM
PSKSRWF*RE*IHQITSSHMRILVHLHCLG**K
PSMYMSYLIS*KAEYKVSHVSQEGNFILSICC*L
YQGMEEVNIAQVALYTQADLSPLLSPLAKQFLS
KKPAGEKQGLPLHFISHC*KLCFEILCLVAQIG
PKKHCLEEDMIGKSRV*KNKYCFTVQRHVYSAL*
MFLSFVVSGKML*EDKSLRRTNRNSELSTELKF
IPVSHAFQECRNY*EADNGVF*KPN*SIFNQIL
*CIK*ILYNILV*QFLLHI*FFQI*YLY*RSIYV
*ICILSNLLLKYIETSFLWKFV*MTEAYMNSRK
FKLQKCICYKMRSLTDRGSLLLIF*KMDS*NLL
K*NCTFGDVS

Sequence NM_002389

GCTCGGGCCACGCCCACCTGTCCTGCAGCACTGGATGCTTTGTGAGTTGGGGATTGTTGCGTCCCATATCTGGACCCAGAAGGGACTTCCCTGCTCGGCT
GGCTCTCGGTTTCTCTGCTTTCCTCCGGAGAAATAACAGCGTCTTCCGCGCCGCGCATGGAGCCTCCCGGCCGCCGCGAGTGTCCCTTTCCTTCCTGGCG
CTTTCCTGGGTTGCTTCTGGCGGCCATGGTGTTGCTGCTGTACTCCTTCTCCGATGCCTGTGAGGAGCCACCAACATTTGAAGCTATGGAGCTCATTGGT
AAACCAAAACCCTACTATGAGATTGGTGAACGAGTAGATTATAAGTGTAAAAAAGGATACTTCTATATACCTCCTCTTGCCACCCATACTATTTGTGATC
GGAATCATACATGGCTACCTGTCTCAGATGACGCCTGTTATAGAGAAACATGTCCATATATACGGGATCCTTTAAATGGCCAAGCAGTCCCTGCAAATGG
GACTTACGAGTTTGGTTATCAGATGCACTTTATTTGTAATGAGGGTTATTACTTAATTGGTGAAGAAATTCTATATTGTGAACTTAAAGGATCAGTAGCA
ATTTGGAGCGGTAAGCCCCCAATATGTGAAAAGGTTTTGTGTACACCACCTCCAAAAATAAAAAATGGAAAACACACCTTTAGTGAAGTAGAAGTATTTG
AGTATCTTGATGCAGTAACTTATAGTTGTGATCCTGCACCTGGACCAGATCCATTTTCACTTATTGGAGAGAGCACGATTTATTGTGGTGACAATTCAGT
GTGGAGTCGTGCTGCTCCAGAGTGTAAAGTGGTCAAATGTCGATTTCCAGTAGTCGAAAATGGAAAACAGATATCAGGATTTGGAAAAAAATTTTACTAC
AAAGCAACAGTTATGTTTGAATGCGATAAGGGTTTTTACCTCGATGGCAGCGACACAATTGTCTGTGACAGTAACAGTACTTGGGATCCCCCAGTTCCAA
AGTGTCTTAAAGTGCTGCCTCCATCTAGTACAAAACCTCCAGCTTTGAGTCATTCAGTGTCGACTTCTTCCACTACAAAATCTCCAGCGTCCAGTGCCTC
AGGTCCTAGGCCTACTTACAAGCCTCCAGTCTCAAATTATCCAGGATATCCTAAACCTGAGGAAGGAATACTTGACAGTTTGGATGTTTGGGTCATTGCT
GTGATTGTTATTGCCATAGTTGTTGGAGTTGCAGTAATTTGTGTTGTCCCGTACAGATATCTTCAAAGGAGGAAGAAGAAAGGCACATACCTAACTGATG
AGACCCACAGAGAAGTAAAATTTACTTCTCTCTGAGAAGGAGAGATGAGAGAAAGGTTTGCTTTTATCATTAAAAGGAAAGCAGATGGTGGAGCTGAATA
TGCCACTTACCAGACTAAATCAACCACTCCAGCAGAGCAGAGAGGCTGAATAGATTCCACAACCTGGTTTGCCAGTTCATCTTTTGACTCTATTAAAATC
TTCAATAGTTGTTATTCTGTAGTTTCACTCTCATGAGTGCAACTGTGGCTTAGCTAATATTGCAATGTGGCTTGAATGTAGGTAGCATCCTTTGATGCTT
CTTTGAAACTTGTATGAATTTGGGTATGAACAGATTGCCTGCTTTCCCTTAAATAACACTTAGATTTATTGGACCAGTCAGCACAGCATGCCTGGTTGTA
TTAAAGCAGGGATATGCTGTATTTTATAAAATTGGCAAAATTAGAGAAATATAGTTCACAATGAAATTATATTTTCTTTGTAAAGAAAGTGGCTTGAAAT
CTTTTTTGTTCAAAGATTAATGCCAACTCTTAAGATTATTCTTTCACCAACTATAGAATGTATTTTATATATCGTTCATTGTAAAAAGCCCTTAAAAATA
TGTGTATACTACTTTGGCTCTTGTGCATAAAAACAAGAACACTGAAAATTGGGAATATGCACAAACTTGGCTTCTTTAACCAAGAATATTATTGGAAAAT
TCTCTAAAAGTTAATAGGGTAAATTCTCTATTTTTTGTAATGTGTTCGGTGATTTCAGAAAGCTAGAAAGTGTATGTGTGGCATTTGTTTTCACTTTTTA
AAACATCCCTAACTGATCGAATATATCAGTAATTTCAGAATCAGATGCATCCTTTCATAAGAAGTGAGAGGACTCTGACAGCCATAACAGGAGTGCCACT
TCATGGTGCGAAGTGAACACTGTAGTCTTGTTGTTTTCCCAAAGAGAACTCCGTATGTTCTCTTAGGTTGAGTAACCCACTCTGAATTCTGGTTACATGT
GTTTTTCTCTCCCTCCTTAAATAAAGAGAGGGGTTAAACATGCCCTCTAAAAGTAGGTGGTTTTGAAGAGAATAAATTCATCAGATAACCTCAAGTCACA
TGAGAATCTTAGTCCATTTACATTGCCTTGGCTAGTAAAAGCCATCTATGTATATGTCTTACCTCATCTCCTAAAAGGCAGAGTACAAAGTAAGCCATGT
ATCTCAGGAAGGTAACTTCATTTTGTCTATTTGCTGTTGATTGTACCAAGGGATGGAAGAAGTAAATATAGCTCAGGTAGCACTTTATACTCAGGCAGAT
CTCAGCCCTCTACTGAGTCCCTTAGCCAAGCAGTTTCTTTCAAAGAAGCCAGCAGGCGAAAAGCAGGGACTGCCACTGCATTTCATATCACACTGTTAAA
AGTTGTGTTTTGAAATTTTATGTTTAGTTGCACAAATTGGGCCAAAGAAACATTGCCTTGAGGAAGATATGATTGGAAAATCAAGAGTGTAGAAGAATAA
ATACTGTTTTACTGTCCAAAGACATGTTTATAGTGCTCTGTAAATGTTCCTTTCCTTTGTAGTCTCTGGCAAGATGCTTTAGGAAGATAAAAGTTTGAGG
AGAACAAACAGGAATTCTGAATTAAGCACAGAGTTGAAGTTTATACCCGTTTCACATGCTTTTCAAGAATGTCGCAATTACTAAGAAGCAGATAATGGTG
TTTTTTAGAAACCTAATTGAAGTATATTCAACCAAATACTTTAATGTATAAAATAAATATTATACAATATACTTGTATAGCAGTTTCTGCTTCACATTTG
ATTTTTTCAAATTTAATATTTATATTAGAGATCTATATATGTATAAATATGTATTTTGTCAAATTTGTTACTTAAATATATAGAGACCAGTTTTCTCTGG
AAGTTTGTTTAAATGACAGAAGCGTATATGAATTCAAGAAAATTTAAGCTGCAAAAATGTATTTGCTATAAAATGAGAAGTCTCACTGATAGAGGTTCTT
TATTGCTCATTTTTTAAAAAATGGACTCTTGAAATCTGTTAAAATAAAATTGTACATTTGGAGATGTTTCA
  • refseq_CD46.F4 (forward primer)
  • refseq_CD46.R4 (reverse primer)
  • Single exon skipping

Frame 0

ARATPTCPAALDAL*VGDCCVPYLDPEGTSLLG
WLSVSLLSSGEITASSAPRMEPPGRRECPFPSWR
FPGLLLAAMVLLLYSFSDACEEPPTFEAMELIG
KPKPYYEIGERVDYKCKKGYFYIPPLATHTICD
RNHTWLPVSDDACYRETCPYIRDPLNGQAVPANG
TYEFGYQMHFICNEGYYLIGEEILYCELKGSVA
IWSGKPPICEKVLCTPPPKIKNGKHTFSEVEVF
EYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSV
WSRAAPECKVVKCRFPVVENGKQISGFGKKFYY
KATVMFECDKGFYLDGSDTIVCDSNSTWDPPVP
KCLKVLPPSSTKPPALSHSVSTSSTTKSPASSAS
GPRPTYKPPVSNYPGYPKPEEGILDSLDVWVIA
VIVIAIVVGVAVICVVPYRYLQRRKKKGTYLTD
ETHREVKFTSL*EGEMRERFAFIIKRKADGGAEY
ATYQTKSTTPAEQRG*IDSTTWFASSSFDSIKI
FNSCYSVVSLS*VQLWLS*YCNVA*M*VASFDA
SLKLV*IWV*TDCLLSLK*HLDLLDQSAQHAWLY
*SRDMLYFIKLAKLEKYSSQ*NYIFFVKKVA*N
LFCSKINANS*DYSFTNYRMYFIYRSL*KALKN
MCILLWLLCIKTRTLKIGNMHKLGFFNQEYYWKI
L*KLIG*ILYFL*CVR*FQKARKCMCGICFHFL
KHP*LIEYISNFRIRCILS*EVRGL*QP*QECH
FMVRSEHCSLVVFPKRTPYVLLG*VTHSEFWLHV
FFSPSLNKERG*TCPLKVGGFEENKFIR*PQVT
*ES*SIYIALASKSHLCICLTSSPKRQSTK*AM
YLRKVTSFCLFAVDCTKGWKK*I*LR*HFILRQI
SALY*VP*PSSFFQRSQQAKSRDCHCISYHTVK
SCVLKFYV*LHKLGQRNIALRKI*LENQECRRI
NTVLLSKDMFIVLCKCSFPL*SLARCFRKIKV*G
EQTGILN*AQS*SLYPFHMLFKNVAITKKQIMV
FFRNLIEVYSTKYFNV*NKYYTIYLYSSFCFTF
DFFKFNIYIRDLYMYKYVFCQICYLNI*RPVFSG
SLFK*QKRI*IQENLSCKNVFAIK*EVSLIEVL
YCSFFKKWTLEIC*NKIVHLEMF

Frame 1

LGPRPPVLQHWMLCELGIVASHIWTQKGLPCSA
GSRFLCFPPEK*QRLPRRAWSLPAAASVPFLPG
AFLGCFWRPWCCCCTPSPMPVRSHQHLKLWSSLV
NQNPTMRLVNE*IISVKKDTSIYLLLPPILFVI
GIIHGYLSQMTPVIEKHVHIYGIL*MAKQSLQM
GLTSLVIRCTLFVMRVIT*LVKKFYIVNLKDQ*Q
FGAVSPQYVKRFCVHHLQK*KMENTPLVK*KYL
SILMQ*LIVVILHLDQIHFHLLERARFIVVTIQ
CGVVLLQSVKWSNVDFQ*SKMENRYQDLEKNFTT
KQQLCLNAIRVFTSMAATQLSVTVTVLGIPQFQ
SVLKCCLHLVQNLQL*VIQCRLLPLQNLQRPVP
QVLGLLTSLQSQIIQDILNLRKEYLTVWMFGSLL
*LLLP*LLELQ*FVLSRTDIFKGGRRKAHT*LM
RPTEK*NLLLSEKER*EKGLLLSLKGKQMVELN
MPLTRLNQPLQQSREAE*IPQPGLPVHLLTLLKS
SIVVIL*FHSHECNCGLANIAMWLECR*HPLML
L*NLYEFGYEQIACFPLNNT*IYWTSQHSMPGC
IKAGICCIL*NWQN*RNIVHNEIIFSL*RKWLEI
FFVQRLMPTLKIILSPTIECILYIVHCKKPLKI
CVYYFGSCA*KQEH*KLGICTNLASLTKNIIGK
FSKS**GKFSIFCNVFGDFRKLESVCVAFVFTF*
NIPN*SNISVISESDASFHKK*EDSDSHNRSAT
SWCEVNTVVLLFSQRELRMFS*VE*PTLNSGYM
CFSLPP*IKRGVKHAL*K*VVLKRINSSDNLKSH
ENLSPFTLPWLVKAIYVYVLPHLLKGRVQSKPC
ISGR*LHFVYLLLIVPRDGRSKYSSGSTLYSGR
SQPSTESLSQAVSFKEASRRKAGTATAFHITLLK
VVF*NFMFSCTNWAKETLP*GRYDWKIKSVEE*
ILFYCPKTCL*CSVNVPFLCSLWQDALGR*KFE
ENKQEF*IKHRVEVYTRFTCFSRMSQLLRSR*WC
FLET*LKYIQPNTLMYKINIIQYTCIAVSASHL
IFSNLIFILEIYICINMYFVKFVT*IYRDQFSL
EVCLNDRSVYEFKKI*AAKMYLL*NEKSH**RFF
IAHFLKNGLLKSVKIKLYIWRCF

Frame 2

SGHAHLSCSTGCFVSWGLLRPISGPRRDFPARL
ALGFSAFLRRNNSVFRAAHGASRPPRVSLSFLA
LSWVASGGHGVAAVLLLRCL*GATNI*SYGAHW
*TKTLL*DW*TSRL*V*KRILLYTSSCHPYYL*S
ESYMATCLR*RLL*RNMSIYTGSFKWPSSPCKW
DLRVWLSDALYL**GLLLNW*RNSIL*T*RISS
NLER*APNM*KGFVYTTSKNKKWKTHL**SRSI*
VS*CSNL*L*SCTWTRSIFTYWREHDLLW*QFS
VESCCSRV*SGQMSISSSRKWKTDIRIWKKILL
QSNSYV*MR*GFLPRWQRHNCL*Q*QYLGSPSSK
VS*SAASI*YKTSSFESFSVDFFHYKISSVQCL
RS*AYLQASSLKLSRIS*T*GRNT*QFGCLGHC
CDCYCHSCWSCSNLCCPVQISSKEEEERHIPN**
DPQRSKIYFSLRRRDERKVCFYH*KESRWWS*I
CHLPD*INHSSRAERLNRFHNLVCQFIF*LY*N
LQ*LLFCSFTLMSATVA*LILQCGLNVGSIL*CF
FETCMNLGMNRLPAFP*ITLRFIGPVSTACLVV
LKQGYAVFYKIGKIREI*FTMKLYFLCKESGLK
SFLFKD*CQLLRLFFHQL*NVFYISFIVKSP*KY
VYTTLALVHKNKNTENWEYAQTWLL*PRILLEN
SLKVNRVNSLFFVMCSVISES*KVYVWHLFSLF
KTSLTDRIYQ*FQNQMHPFIRSERTLTAITGVPL
HGAK*TL*SCCFPKENSVCSLRLSNPL*ILVTC
VFLSLLK*REGLNMPSKSRWF*RE*IHQITSSH
MRILVHLHCLG**KPSMYMSYLIS*KAEYKVSHV
SQEGNFILSICC*LYQGMEEVNIAQVALYTQAD
LSPLLSPLAKQFLSKKPAGEKQGLPLHFISHC*
KLCFEILCLVAQIGPKKHCLEEDMIGKSRV*KNK
YCFTVQRHVYSAL*MFLSFVVSGKML*EDKSLR
RTNRNSELSTELKFIPVSHAFQECRNY*EADNG
VF*KPN*SIFNQIL*CIK*ILYNILV*QFLLHI*
FFQI*YLY*RSIYV*ICILSNLLLKYIETSFLW
KFV*MTEAYMNSRKFKLQKCICYKMRSLTDRGS
LLLIF*KMDS*NLLK*NCTFGDVS

Sequence NM_172359

GCTCGGGCCACGCCCACCTGTCCTGCAGCACTGGATGCTTTGTGAGTTGGGGATTGTTGCGTCCCATATCTGGACCCAGAAGGGACTTCCCTGCTCGGCT
GGCTCTCGGTTTCTCTGCTTTCCTCCGGAGAAATAACAGCGTCTTCCGCGCCGCGCATGGAGCCTCCCGGCCGCCGCGAGTGTCCCTTTCCTTCCTGGCG
CTTTCCTGGGTTGCTTCTGGCGGCCATGGTGTTGCTGCTGTACTCCTTCTCCGATGCCTGTGAGGAGCCACCAACATTTGAAGCTATGGAGCTCATTGGT
AAACCAAAACCCTACTATGAGATTGGTGAACGAGTAGATTATAAGTGTAAAAAAGGATACTTCTATATACCTCCTCTTGCCACCCATACTATTTGTGATC
GGAATCATACATGGCTACCTGTCTCAGATGACGCCTGTTATAGAGAAACATGTCCATATATACGGGATCCTTTAAATGGCCAAGCAGTCCCTGCAAATGG
GACTTACGAGTTTGGTTATCAGATGCACTTTATTTGTAATGAGGGTTATTACTTAATTGGTGAAGAAATTCTATATTGTGAACTTAAAGGATCAGTAGCA
ATTTGGAGCGGTAAGCCCCCAATATGTGAAAAGGTTTTGTGTACACCACCTCCAAAAATAAAAAATGGAAAACACACCTTTAGTGAAGTAGAAGTATTTG
AGTATCTTGATGCAGTAACTTATAGTTGTGATCCTGCACCTGGACCAGATCCATTTTCACTTATTGGAGAGAGCACGATTTATTGTGGTGACAATTCAGT
GTGGAGTCGTGCTGCTCCAGAGTGTAAAGTGGTCAAATGTCGATTTCCAGTAGTCGAAAATGGAAAACAGATATCAGGATTTGGAAAAAAATTTTACTAC
AAAGCAACAGTTATGTTTGAATGCGATAAGGGTTTTTACCTCGATGGCAGCGACACAATTGTCTGTGACAGTAACAGTACTTGGGATCCCCCAGTTCCAA
AGTGTCTTAAAGTGCTGCCTCCATCTAGTACAAAACCTCCAGCTTTGAGTCATTCAGTGTCGACTTCTTCCACTACAAAATCTCCAGCGTCCAGTGCCTC
AGGTCCTAGGCCTACTTACAAGCCTCCAGTCTCAAATTATCCAGGATATCCTAAACCTGAGGAAGGAATACTTGACAGTTTGGATGTTTGGGTCATTGCT
GTGATTGTTATTGCCATAGTTGTTGGAGTTGCAGTAATTTGTGTTGTCCCGTACAGATATCTTCAAAGGAGGAAGAAGAAAGGGAAAGCAGATGGTGGAG
CTGAATATGCCACTTACCAGACTAAATCAACCACTCCAGCAGAGCAGAGAGGCTGAATAGATTCCACAACCTGGTTTGCCAGTTCATCTTTTGACTCTAT
TAAAATCTTCAATAGTTGTTATTCTGTAGTTTCACTCTCATGAGTGCAACTGTGGCTTAGCTAATATTGCAATGTGGCTTGAATGTAGGTAGCATCCTTT
GATGCTTCTTTGAAACTTGTATGAATTTGGGTATGAACAGATTGCCTGCTTTCCCTTAAATAACACTTAGATTTATTGGACCAGTCAGCACAGCATGCCT
GGTTGTATTAAAGCAGGGATATGCTGTATTTTATAAAATTGGCAAAATTAGAGAAATATAGTTCACAATGAAATTATATTTTCTTTGTAAAGAAAGTGGC
TTGAAATCTTTTTTGTTCAAAGATTAATGCCAACTCTTAAGATTATTCTTTCACCAACTATAGAATGTATTTTATATATCGTTCATTGTAAAAAGCCCTT
AAAAATATGTGTATACTACTTTGGCTCTTGTGCATAAAAACAAGAACACTGAAAATTGGGAATATGCACAAACTTGGCTTCTTTAACCAAGAATATTATT
GGAAAATTCTCTAAAAGTTAATAGGGTAAATTCTCTATTTTTTGTAATGTGTTCGGTGATTTCAGAAAGCTAGAAAGTGTATGTGTGGCATTTGTTTTCA
CTTTTTAAAACATCCCTAACTGATCGAATATATCAGTAATTTCAGAATCAGATGCATCCTTTCATAAGAAGTGAGAGGACTCTGACAGCCATAACAGGAG
TGCCACTTCATGGTGCGAAGTGAACACTGTAGTCTTGTTGTTTTCCCAAAGAGAACTCCGTATGTTCTCTTAGGTTGAGTAACCCACTCTGAATTCTGGT
TACATGTGTTTTTCTCTCCCTCCTTAAATAAAGAGAGGGGTTAAACATGCCCTCTAAAAGTAGGTGGTTTTGAAGAGAATAAATTCATCAGATAACCTCA
AGTCACATGAGAATCTTAGTCCATTTACATTGCCTTGGCTAGTAAAAGCCATCTATGTATATGTCTTACCTCATCTCCTAAAAGGCAGAGTACAAAGTAA
GCCATGTATCTCAGGAAGGTAACTTCATTTTGTCTATTTGCTGTTGATTGTACCAAGGGATGGAAGAAGTAAATATAGCTCAGGTAGCACTTTATACTCA
GGCAGATCTCAGCCCTCTACTGAGTCCCTTAGCCAAGCAGTTTCTTTCAAAGAAGCCAGCAGGCGAAAAGCAGGGACTGCCACTGCATTTCATATCACAC
TGTTAAAAGTTGTGTTTTGAAATTTTATGTTTAGTTGCACAAATTGGGCCAAAGAAACATTGCCTTGAGGAAGATATGATTGGAAAATCAAGAGTGTAGA
AGAATAAATACTGTTTTACTGTCCAAAGACATGTTTATAGTGCTCTGTAAATGTTCCTTTCCTTTGTAGTCTCTGGCAAGATGCTTTAGGAAGATAAAAG
TTTGAGGAGAACAAACAGGAATTCTGAATTAAGCACAGAGTTGAAGTTTATACCCGTTTCACATGCTTTTCAAGAATGTCGCAATTACTAAGAAGCAGAT
AATGGTGTTTTTTAGAAACCTAATTGAAGTATATTCAACCAAATACTTTAATGTATAAAATAAATATTATACAATATACTTGTATAGCAGTTTCTGCTTC
ACATTTGATTTTTTCAAATTTAATATTTATATTAGAGATCTATATATGTATAAATATGTATTTTGTCAAATTTGTTACTTAAATATATAGAGACCAGTTT
TCTCTGGAAGTTTGTTTAAATGACAGAAGCGTATATGAATTCAAGAAAATTTAAGCTGCAAAAATGTATTTGCTATAAAATGAGAAGTCTCACTGATAGA
GGTTCTTTATTGCTCATTTTTTAAAAAATGGACTCTTGAAATCTGTTAAAATAAAATTGTACATTTGGAGATGTTTCA
  • refseq_CD46.F4 (forward primer)
  • refseq_CD46.R4 (reverse primer)
  • Single exon skipping

Frame 0

ARATPTCPAALDAL*VGDCCVPYLDPEGTSLLG
WLSVSLLSSGEITASSAPRMEPPGRRECPFPSWR
FPGLLLAAMVLLLYSFSDACEEPPTFEAMELIG
KPKPYYEIGERVDYKCKKGYFYIPPLATHTICD
RNHTWLPVSDDACYRETCPYIRDPLNGQAVPANG
TYEFGYQMHFICNEGYYLIGEEILYCELKGSVA
IWSGKPPICEKVLCTPPPKIKNGKHTFSEVEVF
EYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSV
WSRAAPECKVVKCRFPVVENGKQISGFGKKFYY
KATVMFECDKGFYLDGSDTIVCDSNSTWDPPVP
KCLKVLPPSSTKPPALSHSVSTSSTTKSPASSAS
GPRPTYKPPVSNYPGYPKPEEGILDSLDVWVIA
VIVIAIVVGVAVICVVPYRYLQRRKKKGKADGG
AEYATYQTKSTTPAEQRG*IDSTTWFASSSFDSI
KIFNSCYSVVSLS*VQLWLS*YCNVA*M*VASF
DASLKLV*IWV*TDCLLSLK*HLDLLDQSAQHA
WLY*SRDMLYFIKLAKLEKYSSQ*NYIFFVKKVA
*NLFCSKINANS*DYSFTNYRMYFIYRSL*KAL
KNMCILLWLLCIKTRTLKIGNMHKLGFFNQEYY
WKIL*KLIG*ILYFL*CVR*FQKARKCMCGICFH
FLKHP*LIEYISNFRIRCILS*EVRGL*QP*QE
CHFMVRSEHCSLVVFPKRTPYVLLG*VTHSEFW
LHVFFSPSLNKERG*TCPLKVGGFEENKFIR*PQ
VT*ES*SIYIALASKSHLCICLTSSPKRQSTK*
AMYLRKVTSFCLFAVDCTKGWKK*I*LR*HFIL
RQISALY*VP*PSSFFQRSQQAKSRDCHCISYHT
VKSCVLKFYV*LHKLGQRNIALRKI*LENQECR
RINTVLLSKDMFIVLCKCSFPL*SLARCFRKIK
V*GEQTGILN*AQS*SLYPFHMLFKNVAITKKQI
MVFFRNLIEVYSTKYFNV*NKYYTIYLYSSFCF
TFDFFKFNIYIRDLYMYKYVFCQICYLNI*RPV
FSGSLFK*QKRI*IQENLSCKNVFAIK*EVSLIE
VLYCSFFKKWTLEIC*NKIVHLEMF

Frame 1

LGPRPPVLQHWMLCELGIVASHIWTQKGLPCSA
GSRFLCFPPEK*QRLPRRAWSLPAAASVPFLPG
AFLGCFWRPWCCCCTPSPMPVRSHQHLKLWSSLV
NQNPTMRLVNE*IISVKKDTSIYLLLPPILFVI
GIIHGYLSQMTPVIEKHVHIYGIL*MAKQSLQM
GLTSLVIRCTLFVMRVIT*LVKKFYIVNLKDQ*Q
FGAVSPQYVKRFCVHHLQK*KMENTPLVK*KYL
SILMQ*LIVVILHLDQIHFHLLERARFIVVTIQ
CGVVLLQSVKWSNVDFQ*SKMENRYQDLEKNFTT
KQQLCLNAIRVFTSMAATQLSVTVTVLGIPQFQ
SVLKCCLHLVQNLQL*VIQCRLLPLQNLQRPVP
QVLGLLTSLQSQIIQDILNLRKEYLTVWMFGSLL
*LLLP*LLELQ*FVLSRTDIFKGGRRKGKQMVE
LNMPLTRLNQPLQQSREAE*IPQPGLPVHLLTL
LKSSIVVIL*FHSHECNCGLANIAMWLECR*HPL
MLL*NLYEFGYEQIACFPLNNT*IYWTSQHSMP
GCIKAGICCIL*NWQN*RNIVHNEIIFSL*RKW
LEIFFVQRLMPTLKIILSPTIECILYIVHCKKPL
KICVYYFGSCA*KQEH*KLGICTNLASLTKNII
GKFSKS**GKFSIFCNVFGDFRKLESVCVAFVF
TF*NIPN*SNISVISESDASFHKK*EDSDSHNRS
ATSWCEVNTVVLLFSQRELRMFS*VE*PTLNSG
YMCFSLPP*IKRGVKHAL*K*VVLKRINSSDNL
KSHENLSPFTLPWLVKAIYVYVLPHLLKGRVQSK
PCISGR*LHFVYLLLIVPRDGRSKYSSGSTLYS
GRSQPSTESLSQAVSFKEASRRKAGTATAFHIT
LLKVVF*NFMFSCTNWAKETLP*GRYDWKIKSVE
E*ILFYCPKTCL*CSVNVPFLCSLWQDALGR*K
FEENKQEF*IKHRVEVYTRFTCFSRMSQLLRSR
*WCFLET*LKYIQPNTLMYKINIIQYTCIAVSAS
HLIFSNLIFILEIYICINMYFVKFVT*IYRDQF
SLEVCLNDRSVYEFKKI*AAKMYLL*NEKSH**
RFFIAHFLKNGLLKSVKIKLYIWRCF

Frame 2

SGHAHLSCSTGCFVSWGLLRPISGPRRDFPARL
ALGFSAFLRRNNSVFRAAHGASRPPRVSLSFLA
LSWVASGGHGVAAVLLLRCL*GATNI*SYGAHW
*TKTLL*DW*TSRL*V*KRILLYTSSCHPYYL*S
ESYMATCLR*RLL*RNMSIYTGSFKWPSSPCKW
DLRVWLSDALYL**GLLLNW*RNSIL*T*RISS
NLER*APNM*KGFVYTTSKNKKWKTHL**SRSI*
VS*CSNL*L*SCTWTRSIFTYWREHDLLW*QFS
VESCCSRV*SGQMSISSSRKWKTDIRIWKKILL
QSNSYV*MR*GFLPRWQRHNCL*Q*QYLGSPSSK
VS*SAASI*YKTSSFESFSVDFFHYKISSVQCL
RS*AYLQASSLKLSRIS*T*GRNT*QFGCLGHC
CDCYCHSCWSCSNLCCPVQISSKEEEERESRWWS
*ICHLPD*INHSSRAERLNRFHNLVCQFIF*LY
*NLQ*LLFCSFTLMSATVA*LILQCGLNVGSIL
*CFFETCMNLGMNRLPAFP*ITLRFIGPVSTACL
VVLKQGYAVFYKIGKIREI*FTMKLYFLCKESG
LKSFLFKD*CQLLRLFFHQL*NVFYISFIVKSP
*KYVYTTLALVHKNKNTENWEYAQTWLL*PRILL
ENSLKVNRVNSLFFVMCSVISES*KVYVWHLFS
LFKTSLTDRIYQ*FQNQMHPFIRSERTLTAITG
VPLHGAK*TL*SCCFPKENSVCSLRLSNPL*ILV
TCVFLSLLK*REGLNMPSKSRWF*RE*IHQITS
SHMRILVHLHCLG**KPSMYMSYLIS*KAEYKV
SHVSQEGNFILSICC*LYQGMEEVNIAQVALYTQ
ADLSPLLSPLAKQFLSKKPAGEKQGLPLHFISH
C*KLCFEILCLVAQIGPKKHCLEEDMIGKSRV*
KNKYCFTVQRHVYSAL*MFLSFVVSGKML*EDKS
LRRTNRNSELSTELKFIPVSHAFQECRNY*EAD
NGVF*KPN*SIFNQIL*CIK*ILYNILV*QFLL
HI*FFQI*YLY*RSIYV*ICILSNLLLKYIETSF
LWKFV*MTEAYMNSRKFKLQKCICYKMRSLTDR
GSLLLIF*KMDS*NLLK*NCTFGDVS

Sequence NM_172360

GCTCGGGCCACGCCCACCTGTCCTGCAGCACTGGATGCTTTGTGAGTTGGGGATTGTTGCGTCCCATATCTGGACCCAGAAGGGACTTCCCTGCTCGGCT
GGCTCTCGGTTTCTCTGCTTTCCTCCGGAGAAATAACAGCGTCTTCCGCGCCGCGCATGGAGCCTCCCGGCCGCCGCGAGTGTCCCTTTCCTTCCTGGCG
CTTTCCTGGGTTGCTTCTGGCGGCCATGGTGTTGCTGCTGTACTCCTTCTCCGATGCCTGTGAGGAGCCACCAACATTTGAAGCTATGGAGCTCATTGGT
AAACCAAAACCCTACTATGAGATTGGTGAACGAGTAGATTATAAGTGTAAAAAAGGATACTTCTATATACCTCCTCTTGCCACCCATACTATTTGTGATC
GGAATCATACATGGCTACCTGTCTCAGATGACGCCTGTTATAGAGAAACATGTCCATATATACGGGATCCTTTAAATGGCCAAGCAGTCCCTGCAAATGG
GACTTACGAGTTTGGTTATCAGATGCACTTTATTTGTAATGAGGGTTATTACTTAATTGGTGAAGAAATTCTATATTGTGAACTTAAAGGATCAGTAGCA
ATTTGGAGCGGTAAGCCCCCAATATGTGAAAAGGTTTTGTGTACACCACCTCCAAAAATAAAAAATGGAAAACACACCTTTAGTGAAGTAGAAGTATTTG
AGTATCTTGATGCAGTAACTTATAGTTGTGATCCTGCACCTGGACCAGATCCATTTTCACTTATTGGAGAGAGCACGATTTATTGTGGTGACAATTCAGT
GTGGAGTCGTGCTGCTCCAGAGTGTAAAGTGGTCAAATGTCGATTTCCAGTAGTCGAAAATGGAAAACAGATATCAGGATTTGGAAAAAAATTTTACTAC
AAAGCAACAGTTATGTTTGAATGCGATAAGGGTTTTTACCTCGATGGCAGCGACACAATTGTCTGTGACAGTAACAGTACTTGGGATCCCCCAGTTCCAA
AGTGTCTTAAAGTGCTGCCTCCATCTAGTACAAAACCTCCAGCTTTGAGTCATTCAGTGTCGACTTCTTCCACTACAAAATCTCCAGCGTCCAGTGCCTC
AGGATATCCTAAACCTGAGGAAGGAATACTTGACAGTTTGGATGTTTGGGTCATTGCTGTGATTGTTATTGCCATAGTTGTTGGAGTTGCAGTAATTTGT
GTTGTCCCGTACAGATATCTTCAAAGGAGGAAGAAGAAAGGGAAAGCAGATGGTGGAGCTGAATATGCCACTTACCAGACTAAATCAACCACTCCAGCAG
AGCAGAGAGGCTGAATAGATTCCACAACCTGGTTTGCCAGTTCATCTTTTGACTCTATTAAAATCTTCAATAGTTGTTATTCTGTAGTTTCACTCTCATG
AGTGCAACTGTGGCTTAGCTAATATTGCAATGTGGCTTGAATGTAGGTAGCATCCTTTGATGCTTCTTTGAAACTTGTATGAATTTGGGTATGAACAGAT
TGCCTGCTTTCCCTTAAATAACACTTAGATTTATTGGACCAGTCAGCACAGCATGCCTGGTTGTATTAAAGCAGGGATATGCTGTATTTTATAAAATTGG
CAAAATTAGAGAAATATAGTTCACAATGAAATTATATTTTCTTTGTAAAGAAAGTGGCTTGAAATCTTTTTTGTTCAAAGATTAATGCCAACTCTTAAGA
TTATTCTTTCACCAACTATAGAATGTATTTTATATATCGTTCATTGTAAAAAGCCCTTAAAAATATGTGTATACTACTTTGGCTCTTGTGCATAAAAACA
AGAACACTGAAAATTGGGAATATGCACAAACTTGGCTTCTTTAACCAAGAATATTATTGGAAAATTCTCTAAAAGTTAATAGGGTAAATTCTCTATTTTT
TGTAATGTGTTCGGTGATTTCAGAAAGCTAGAAAGTGTATGTGTGGCATTTGTTTTCACTTTTTAAAACATCCCTAACTGATCGAATATATCAGTAATTT
CAGAATCAGATGCATCCTTTCATAAGAAGTGAGAGGACTCTGACAGCCATAACAGGAGTGCCACTTCATGGTGCGAAGTGAACACTGTAGTCTTGTTGTT
TTCCCAAAGAGAACTCCGTATGTTCTCTTAGGTTGAGTAACCCACTCTGAATTCTGGTTACATGTGTTTTTCTCTCCCTCCTTAAATAAAGAGAGGGGTT
AAACATGCCCTCTAAAAGTAGGTGGTTTTGAAGAGAATAAATTCATCAGATAACCTCAAGTCACATGAGAATCTTAGTCCATTTACATTGCCTTGGCTAG
TAAAAGCCATCTATGTATATGTCTTACCTCATCTCCTAAAAGGCAGAGTACAAAGTAAGCCATGTATCTCAGGAAGGTAACTTCATTTTGTCTATTTGCT
GTTGATTGTACCAAGGGATGGAAGAAGTAAATATAGCTCAGGTAGCACTTTATACTCAGGCAGATCTCAGCCCTCTACTGAGTCCCTTAGCCAAGCAGTT
TCTTTCAAAGAAGCCAGCAGGCGAAAAGCAGGGACTGCCACTGCATTTCATATCACACTGTTAAAAGTTGTGTTTTGAAATTTTATGTTTAGTTGCACAA
ATTGGGCCAAAGAAACATTGCCTTGAGGAAGATATGATTGGAAAATCAAGAGTGTAGAAGAATAAATACTGTTTTACTGTCCAAAGACATGTTTATAGTG
CTCTGTAAATGTTCCTTTCCTTTGTAGTCTCTGGCAAGATGCTTTAGGAAGATAAAAGTTTGAGGAGAACAAACAGGAATTCTGAATTAAGCACAGAGTT
GAAGTTTATACCCGTTTCACATGCTTTTCAAGAATGTCGCAATTACTAAGAAGCAGATAATGGTGTTTTTTAGAAACCTAATTGAAGTATATTCAACCAA
ATACTTTAATGTATAAAATAAATATTATACAATATACTTGTATAGCAGTTTCTGCTTCACATTTGATTTTTTCAAATTTAATATTTATATTAGAGATCTA
TATATGTATAAATATGTATTTTGTCAAATTTGTTACTTAAATATATAGAGACCAGTTTTCTCTGGAAGTTTGTTTAAATGACAGAAGCGTATATGAATTC
AAGAAAATTTAAGCTGCAAAAATGTATTTGCTATAAAATGAGAAGTCTCACTGATAGAGGTTCTTTATTGCTCATTTTTTAAAAAATGGACTCTTGAAAT
CTGTTAAAATAAAATTGTACATTTGGAGATGTTTCA
  • refseq_CD46.F4 (forward primer)
  • refseq_CD46.R4 (reverse primer)
  • Single exon skipping

Frame 0

ARATPTCPAALDAL*VGDCCVPYLDPEGTSLLG
WLSVSLLSSGEITASSAPRMEPPGRRECPFPSWR
FPGLLLAAMVLLLYSFSDACEEPPTFEAMELIG
KPKPYYEIGERVDYKCKKGYFYIPPLATHTICD
RNHTWLPVSDDACYRETCPYIRDPLNGQAVPANG
TYEFGYQMHFICNEGYYLIGEEILYCELKGSVA
IWSGKPPICEKVLCTPPPKIKNGKHTFSEVEVF
EYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSV
WSRAAPECKVVKCRFPVVENGKQISGFGKKFYY
KATVMFECDKGFYLDGSDTIVCDSNSTWDPPVP
KCLKVLPPSSTKPPALSHSVSTSSTTKSPASSAS
GYPKPEEGILDSLDVWVIAVIVIAIVVGVAVIC
VVPYRYLQRRKKKGKADGGAEYATYQTKSTTPA
EQRG*IDSTTWFASSSFDSIKIFNSCYSVVSLS*
VQLWLS*YCNVA*M*VASFDASLKLV*IWV*TD
CLLSLK*HLDLLDQSAQHAWLY*SRDMLYFIKL
AKLEKYSSQ*NYIFFVKKVA*NLFCSKINANS*D
YSFTNYRMYFIYRSL*KALKNMCILLWLLCIKT
RTLKIGNMHKLGFFNQEYYWKIL*KLIG*ILYF
L*CVR*FQKARKCMCGICFHFLKHP*LIEYISNF
RIRCILS*EVRGL*QP*QECHFMVRSEHCSLVV
FPKRTPYVLLG*VTHSEFWLHVFFSPSLNKERG
*TCPLKVGGFEENKFIR*PQVT*ES*SIYIALAS
KSHLCICLTSSPKRQSTK*AMYLRKVTSFCLFA
VDCTKGWKK*I*LR*HFILRQISALY*VP*PSS
FFQRSQQAKSRDCHCISYHTVKSCVLKFYV*LHK
LGQRNIALRKI*LENQECRRINTVLLSKDMFIV
LCKCSFPL*SLARCFRKIKV*GEQTGILN*AQS
*SLYPFHMLFKNVAITKKQIMVFFRNLIEVYSTK
YFNV*NKYYTIYLYSSFCFTFDFFKFNIYIRDL
YMYKYVFCQICYLNI*RPVFSGSLFK*QKRI*I
QENLSCKNVFAIK*EVSLIEVLYCSFFKKWTLEI
C*NKIVHLEMF

Frame 1

LGPRPPVLQHWMLCELGIVASHIWTQKGLPCSA
GSRFLCFPPEK*QRLPRRAWSLPAAASVPFLPG
AFLGCFWRPWCCCCTPSPMPVRSHQHLKLWSSLV
NQNPTMRLVNE*IISVKKDTSIYLLLPPILFVI
GIIHGYLSQMTPVIEKHVHIYGIL*MAKQSLQM
GLTSLVIRCTLFVMRVIT*LVKKFYIVNLKDQ*Q
FGAVSPQYVKRFCVHHLQK*KMENTPLVK*KYL
SILMQ*LIVVILHLDQIHFHLLERARFIVVTIQ
CGVVLLQSVKWSNVDFQ*SKMENRYQDLEKNFTT
KQQLCLNAIRVFTSMAATQLSVTVTVLGIPQFQ
SVLKCCLHLVQNLQL*VIQCRLLPLQNLQRPVP
QDILNLRKEYLTVWMFGSLL*LLLP*LLELQ*FV
LSRTDIFKGGRRKGKQMVELNMPLTRLNQPLQQ
SREAE*IPQPGLPVHLLTLLKSSIVVIL*FHSH
ECNCGLANIAMWLECR*HPLMLL*NLYEFGYEQI
ACFPLNNT*IYWTSQHSMPGCIKAGICCIL*NW
QN*RNIVHNEIIFSL*RKWLEIFFVQRLMPTLK
IILSPTIECILYIVHCKKPLKICVYYFGSCA*KQ
EH*KLGICTNLASLTKNIIGKFSKS**GKFSIF
CNVFGDFRKLESVCVAFVFTF*NIPN*SNISVI
SESDASFHKK*EDSDSHNRSATSWCEVNTVVLLF
SQRELRMFS*VE*PTLNSGYMCFSLPP*IKRGV
KHAL*K*VVLKRINSSDNLKSHENLSPFTLPWL
VKAIYVYVLPHLLKGRVQSKPCISGR*LHFVYLL
LIVPRDGRSKYSSGSTLYSGRSQPSTESLSQAV
SFKEASRRKAGTATAFHITLLKVVF*NFMFSCT
NWAKETLP*GRYDWKIKSVEE*ILFYCPKTCL*C
SVNVPFLCSLWQDALGR*KFEENKQEF*IKHRV
EVYTRFTCFSRMSQLLRSR*WCFLET*LKYIQP
NTLMYKINIIQYTCIAVSASHLIFSNLIFILEIY
ICINMYFVKFVT*IYRDQFSLEVCLNDRSVYEF
KKI*AAKMYLL*NEKSH**RFFIAHFLKNGLLK
SVKIKLYIWRCF

Frame 2

SGHAHLSCSTGCFVSWGLLRPISGPRRDFPARL
ALGFSAFLRRNNSVFRAAHGASRPPRVSLSFLA
LSWVASGGHGVAAVLLLRCL*GATNI*SYGAHW
*TKTLL*DW*TSRL*V*KRILLYTSSCHPYYL*S
ESYMATCLR*RLL*RNMSIYTGSFKWPSSPCKW
DLRVWLSDALYL**GLLLNW*RNSIL*T*RISS
NLER*APNM*KGFVYTTSKNKKWKTHL**SRSI*
VS*CSNL*L*SCTWTRSIFTYWREHDLLW*QFS
VESCCSRV*SGQMSISSSRKWKTDIRIWKKILL
QSNSYV*MR*GFLPRWQRHNCL*Q*QYLGSPSSK
VS*SAASI*YKTSSFESFSVDFFHYKISSVQCL
RIS*T*GRNT*QFGCLGHCCDCYCHSCWSCSNL
CCPVQISSKEEEERESRWWS*ICHLPD*INHSSR
AERLNRFHNLVCQFIF*LY*NLQ*LLFCSFTLM
SATVA*LILQCGLNVGSIL*CFFETCMNLGMNR
LPAFP*ITLRFIGPVSTACLVVLKQGYAVFYKIG
KIREI*FTMKLYFLCKESGLKSFLFKD*CQLLR
LFFHQL*NVFYISFIVKSP*KYVYTTLALVHKN
KNTENWEYAQTWLL*PRILLENSLKVNRVNSLFF
VMCSVISES*KVYVWHLFSLFKTSLTDRIYQ*F
QNQMHPFIRSERTLTAITGVPLHGAK*TL*SCC
FPKENSVCSLRLSNPL*ILVTCVFLSLLK*REGL
NMPSKSRWF*RE*IHQITSSHMRILVHLHCLG*
*KPSMYMSYLIS*KAEYKVSHVSQEGNFILSIC
C*LYQGMEEVNIAQVALYTQADLSPLLSPLAKQF
LSKKPAGEKQGLPLHFISHC*KLCFEILCLVAQ
IGPKKHCLEEDMIGKSRV*KNKYCFTVQRHVYS
AL*MFLSFVVSGKML*EDKSLRRTNRNSELSTEL
KFIPVSHAFQECRNY*EADNGVF*KPN*SIFNQ
IL*CIK*ILYNILV*QFLLHI*FFQI*YLY*RS
IYV*ICILSNLLLKYIETSFLWKFV*MTEAYMNS
RKFKLQKCICYKMRSLTDRGSLLLIF*KMDS*N
LLK*NCTFGDVS

Copyright ©2008,2017, all rights reserved.