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Sequences

Sequence NM_138940

refseq_CD200R1.F2 (forward primer)
refseq_CD200R1.R2 (reverse primer)
Single exon skipping

Frame 0

IAVSSSREKLLFVQVTNQAKPHRREGRG*KEGS APLLMG*EDPVLRS*PERVSPCAQFLLYLCGGKV LSEGQKKRKQKCSALGELLT*GYC*F*LSS*WP LQAVYVWMKNRLHRTTRKYSQKLTLHGL*RWLQ MLCFVALLSH*EI*S**HGK*S*EASLPAQKPTR KKQMRPRKPTVLMRE*PGSPDLIRIRTFRFVPW PSLMTGITDA*W*HLMGISIVDITSKC*VRSII Y*GISHHQICDGNKCLSEFHMLYVKTEAFFSLFP LCSYT*SDPVSKQE*NCSMQGSCREASCAYLLD PRGRLCH*ARILEQWHSD

Frame 1

LLCQVPEKSFCSSKLLTRLNHIDVKEGARRKGV PHC*WGKRILY*EVDQRGSHHAHSSFCTCVEEK Y*VKGRKRENRNALPLENC*PRATVDFDYLLSGR FKQFMYG*KTDYTELLESTRRS*HFMACKDGYK CCALLPSYRIKKFDHNNMGNNPERPAFLHKSLQ ERNK*DQGNQLY**ENNLGLQT*SEFGPSDSYRG HHS*RVLQMHNGNT*WEFPSWISPPSVR*GASY IEVFHITRFVTETNVSLNSICFM*KPKHFFPSF LSAVTPEVTLFQNRNRTAVCKAVAGKPAAHISWI PEGDCATKQEYWSNGTVT

Frame 2

CCVKFQRKASVRPSY*PG*TT*T*RKGLEGREC PTVDGVRGSCTEKLTREGLTMRTVPSVPVWRKS TE*RAEKEKTEMLCPWRTANLGLLLILTIFLVA ASSSLCMDEKQITQNYSKVLAEVNTSWPVKMATN AVLCCPPIALRNLIIITWEIILRGQPSCTKAYK KETNETKETNCTDERITWVSRPDQNSDLQIRTV AITHDGYYRCIMVTPDGNFHRGYHLQVLGKEHHI LRYFTSPDL*RKQMSL*IPYALCENRSIFFPLS SLQLHLK*PCFKTGIELQYARQLQGSQLRISPG SQRAIVPLSKNTGAMAQ*L

Sequence NM_170780

ATTGCTGTGTCAAGTTCCAGAGAAAAGCTTCTGTTCGTCCAAGTTACTAACCAGGCTAAACCACATAGACGTGAAGGAAGGGGCTAGAAGGAAGGGAGTG CCCCACTGTTGATGGGGTAAGAGGATCCTGTACTGAGAAGTTGACCAGAGAGGGTCTCACCATGCGCACAGTTCCTTCTGTACCTGTGTGGAGGAAAAGT ACTGAGTGAAGGGCAGAAAAAGAGAAAACAGAAATGCTCTGCCCTTGGAGAACTGCTAACCTAGGGCTACTGTTGATTTTGACTATCTTCTTAGTGGCCG CTTCAAGCAGTTTATGTATGGATGAAAAACAGATTACACAGAACTACTCGAAAGTACTCGCAGAAGTTAACACTTCATGGCCTGTAAAGATGGCTACAAA TGCTGTGCTTTGTTGCCCTCCTATCGCATTAAGAAATTTGATCATAATAACATGGGAAATAATCCTGAGAGGCCAGCCTTCCTGCACAAAAGCCTACAAG AAAGAAACAAATGAGACCAAGGAAACCAACTGTACTGATGAGAGAATAACCTGGGTCTCCAGACCTGATCAGAATTCGGACCTTCAGATTCGTACCGTGG CCATCACTCATGACGGGTATTACAGATGCATAATGGTAACACCTGATGGGAATTTCCATCGTGGATATCACCTCCAAGTGTTAGTTACACCTGAAGTGAC CCTGTTTCAAAACAGGAATAGAACTGCAGTATGCAAGGCAGTTGCAGGGAAGCCAGCTGCGCATATCTCCTGGATCCCAGAGGGCGATTGTGCCACTAAG CAAGAATACTGGAGCAATGGCACAGTGACTGTTAAGAGTACATGCCACTGGGAGGTCCACAATGTGTCTACCGTGACCTGCCACGTCTCCCATTTGACTG GCAACAAGAGTCTGTACATAGAGCTACTTCCTGTTCCAGGTGCCAAAAAATCAGCAAAATTATATATTCCATATATCATCCTTACTATTATTATTTTGAC CATCGTGGGATTCATTTGGTTGTTGAAAGTCAATGGCTGCAGAAAATATAAATTGAATAAAACAGAATCTACTCCAGTTGTTGAGGAGGATGAAATGCAG CCCTATGCCAGCTACACAGAGAAGAACAATCCTCTCTATGATACTACAAACAAGGTGAAGGCATCTGAGGCATTACAAAGTGAAGTTGACACAGACCTCC ATACTTTATAAGTTGTTGGACTCTAGTACCAAGAAACAACAACAAACGAGATACATTATAATTACTGTCTGATTTTCTTACAGTTCTAGAATGAAGACTT ATATTGAAATTAGGTTTTCCAAGGTTCTTAGAAGACATTTTAATGGATTCTCATTCATACCCTTGTATAATTGGAATTTTTGATTCTTAGCTGCTACCAG CTAGTTCTCTGAAGAACTGATGTTATTACAAAGAAAATACATGCCCATGACCAAATATTCAAATTGTGCAGGACAGTAAATAATGAAAACCAAATTTCCT CAAGAAATAACTGAAGAAGGAGCAAGTGTGAACAGTTTCTTGTGTATCCTTTCAGAATATTTTAATGTACATATGACATGTGTATATGCCTATGGTATAT GTGTCAATTTATGTGTCCCCTTACATATACATGCACATATCTTTGTCAAGGCACCAGTGGGAACAATACACTGCATTACTGTTCTATACATATGAAAACC TAATAATATAAGTCTTAGAGATCATTTTATATCATGACAAGTAGAGCTACCTCATTCTTTTTAATGGTTATATAAAATTCCATTGTATAGTTATATCATT ATTTAATTAAAAACAACCCTAATGATGGATATTTAGATTCTTTTAAGTTTTGTTTATTTCTTTTAAGTTTTGTTTGTGGTATAAACAATACCACATAGAA TGTTTCTTGTGCATATATCTCTTTGTTTTTGAGTATATCTGTAGGATAACTTTCTTGAGTGGAATTGTCAGGTCAAAGGGTTTGTGCATTTTACTATTGA TATATATGTTAAATTGTGTCAAATATATATGTCAAATTCCCTCCAACATTGTTTAAATGTGCCTTTCCCTAAATTTCTATTTTAATAACTGTACTATTCC TGCTTCTACAGTTGCCACTTTCTCTTTTTAATCAACCAGATTAAATATGATGTGAGATTATAATAAGAATTATACTATTTAATAAAAATGGATTTATATT TTT

refseq_CD200R1.F2 (forward primer)
refseq_CD200R1.R2 (reverse primer)
Single exon skipping

Frame 0

IAVSSSREKLLFVQVTNQAKPHRREGRG*KEGS APLLMG*EDPVLRS*PERVSPCAQFLLYLCGGKV LSEGQKKRKQKCSALGELLT*GYC*F*LSS*WP LQAVYVWMKNRLHRTTRKYSQKLTLHGL*RWLQ MLCFVALLSH*EI*S**HGK*S*EASLPAQKPTR KKQMRPRKPTVLMRE*PGSPDLIRIRTFRFVPW PSLMTGITDA*W*HLMGISIVDITSKC*LHLK* PCFKTGIELQYARQLQGSQLRISPGSQRAIVPLS KNTGAMAQ*LLRVHATGRSTMCLP*PATSPI*L ATRVCT*SYFLFQVPKNQQNYIFHISSLLLLF* PSWDSFGC*KSMAAENIN*IKQNLLQLLRRMKCS PMPATQRRTILSMILQTR*RHLRHYKVKLTQTS ILYKLLDSSTKKQQQTRYIIITV*FSYSSRMKT YIEIRFSKVLRRHFNGFSFIPLYNWNF*FLAATS *FSEELMLLQRKYMPMTKYSNCAGQ*IMKTKFP QEITEEGASVNSFLCILSEYFNVHMTCVYAYGI CVNLCVPLHIHAHIFVKAPVGTIHCITVLYI*KP NNISLRDHFIS*QVELPHSF*WLYKIPLYSYII I*LKTTLMMDI*ILLSFVYFF*VLFVV*TIPHR MFLVHISLCF*VYL*DNFLEWNCQVKGFVHFTID IYVKLCQIYMSNSLQHCLNVPFPKFLF**LYYS CFYSCHFLFLINQIKYDVRL**ELYYLIKMDLY F

Frame 1

LLCQVPEKSFCSSKLLTRLNHIDVKEGARRKGV PHC*WGKRILY*EVDQRGSHHAHSSFCTCVEEK Y*VKGRKRENRNALPLENC*PRATVDFDYLLSGR FKQFMYG*KTDYTELLESTRRS*HFMACKDGYK CCALLPSYRIKKFDHNNMGNNPERPAFLHKSLQ ERNK*DQGNQLY**ENNLGLQT*SEFGPSDSYRG HHS*RVLQMHNGNT*WEFPSWISPPSVSYT*SD PVSKQE*NCSMQGSCREASCAYLLDPRGRLCH* ARILEQWHSDC*EYMPLGGPQCVYRDLPRLPFDW QQESVHRATSCSRCQKISKIIYSIYHPYYYYFD HRGIHLVVESQWLQKI*IE*NRIYSSC*GG*NA ALCQLHREEQSSL*YYKQGEGI*GITK*S*HRPP YFISCWTLVPRNNNKRDTL*LLSDFLTVLE*RL ILKLGFPRFLEDILMDSHSYPCIIGIFDS*LLP ASSLKN*CYYKENTCP*PNIQIVQDSK**KPNFL KK*LKKEQV*TVSCVSFQNILMYI*HVYMPMVY VSIYVSPYIYMHISLSRHQWEQYTALLFYTYEN LII*VLEIILYHDK*SYLILFNGYIKFHCIVISL FN*KQP**WIFRFF*VLFISFKFCLWYKQYHIE CFLCIYLFVFEYICRITFLSGIVRSKGLCILLL IYMLNCVKYICQIPSNIV*MCLSLNFYFNNCTIP ASTVATFSF*STRLNMM*DYNKNYTI**KWIYI F

Frame 2

CCVKFQRKASVRPSY*PG*TT*T*RKGLEGREC PTVDGVRGSCTEKLTREGLTMRTVPSVPVWRKS TE*RAEKEKTEMLCPWRTANLGLLLILTIFLVA ASSSLCMDEKQITQNYSKVLAEVNTSWPVKMATN AVLCCPPIALRNLIIITWEIILRGQPSCTKAYK KETNETKETNCTDERITWVSRPDQNSDLQIRTV AITHDGYYRCIMVTPDGNFHRGYHLQVLVTPEVT LFQNRNRTAVCKAVAGKPAAHISWIPEGDCATK QEYWSNGTVTVKSTCHWEVHNVSTVTCHVSHLT GNKSLYIELLPVPGAKKSAKLYIPYIILTIIILT IVGFIWLLKVNGCRKYKLNKTESTPVVEEDEMQ PYASYTEKNNPLYDTTNKVKASEALQSEVDTDL HTL*VVGL*YQETTTNEIHYNYCLIFLQF*NEDL Y*N*VFQGS*KTF*WILIHTLV*LEFLILSCYQ LVL*RTDVITKKIHAHDQIFKLCRTVNNENQIS SRNN*RRSKCEQFLVYPFRIF*CTYDMCICLWYM CQFMCPLTYTCTYLCQGTSGNNTLHYCSIHMKT **YKS*RSFYIMTSRATSFFLMVI*NSIV*LYH YLIKNNPNDGYLDSFKFCLFLLSFVCGINNTT*N VSCAYISLFLSISVG*LS*VELSGQRVCAFYY* YIC*IVSNIYVKFPPTLFKCAFP*ISILITVLF LLLQLPLSLFNQPD*I*CEIIIRIILFNKNGFIF

Sequence NM_138939

refseq_CD200R1.F2 (forward primer)
refseq_CD200R1.R2 (reverse primer)
Single exon skipping

Frame 0

IAVSSSREKLLFVQVTNQAKPHRREGRG*KEGS APLLMG*EDPVLRS*PERVSPCAQFLLYLCGGKV LSEGQKKRKQKCSALGELLT*GYC*F*LSS*WP KRRVLLNQTTH*CCKLARRIML*LQAVYVWMKN RLHRTTRKYSQKLTLHGL*RWLQMLCFVALLSH* EI*S**HGK*S*EASLPAQKPTRKKQMRPRKPT VLMRE*PGSPDLIRIRTFRFVPWPSLMTGITDA *W*HLMGISIVDITSKC*VRSIIY*GISHHQICD GNKCLSEFHMLYVKTEAFFSLFPLCSYT*SDPV SKQE*NCSMQGSCREASCAYLLDPRGRLCH*AR ILEQWHSD

Frame 1

LLCQVPEKSFCSSKLLTRLNHIDVKEGARRKGV PHC*WGKRILY*EVDQRGSHHAHSSFCTCVEEK Y*VKGRKRENRNALPLENC*PRATVDFDYLLSGR SGGCCSTKQLINAAN*QGESCFSFKQFMYG*KT DYTELLESTRRS*HFMACKDGYKCCALLPSYRI KKFDHNNMGNNPERPAFLHKSLQERNK*DQGNQL Y**ENNLGLQT*SEFGPSDSYRGHHS*RVLQMH NGNT*WEFPSWISPPSVR*GASYIEVFHITRFV TETNVSLNSICFM*KPKHFFPSFLSAVTPEVTLF QNRNRTAVCKAVAGKPAAHISWIPEGDCATKQE YWSNGTVT

Frame 2

CCVKFQRKASVRPSY*PG*TT*T*RKGLEGREC PTVDGVRGSCTEKLTREGLTMRTVPSVPVWRKS TE*RAEKEKTEMLCPWRTANLGLLLILTIFLVA EAEGAAQPNNSLMLQTSKENHALASSSLCMDEKQ ITQNYSKVLAEVNTSWPVKMATNAVLCCPPIAL RNLIIITWEIILRGQPSCTKAYKKETNETKETN CTDERITWVSRPDQNSDLQIRTVAITHDGYYRCI MVTPDGNFHRGYHLQVLGKEHHILRYFTSPDL* RKQMSL*IPYALCENRSIFFPLSSLQLHLK*PC FKTGIELQYARQLQGSQLRISPGSQRAIVPLSKN TGAMAQ*L

Sequence NM_138806

ATTGCTGTGTCAAGTTCCAGAGAAAAGCTTCTGTTCGTCCAAGTTACTAACCAGGCTAAACCACATAGACGTGAAGGAAGGGGCTAGAAGGAAGGGAGTG CCCCACTGTTGATGGGGTAAGAGGATCCTGTACTGAGAAGTTGACCAGAGAGGGTCTCACCATGCGCACAGTTCCTTCTGTACCTGTGTGGAGGAAAAGT ACTGAGTGAAGGGCAGAAAAAGAGAAAACAGAAATGCTCTGCCCTTGGAGAACTGCTAACCTAGGGCTACTGTTGATTTTGACTATCTTCTTAGTGGCCG AAGCGGAGGGTGCTGCTCAACCAAACAACTCATTAATGCTGCAAACTAGCAAGGAGAATCATGCTTTAGCTTCAAGCAGTTTATGTATGGATGAAAAACA GATTACACAGAACTACTCGAAAGTACTCGCAGAAGTTAACACTTCATGGCCTGTAAAGATGGCTACAAATGCTGTGCTTTGTTGCCCTCCTATCGCATTA AGAAATTTGATCATAATAACATGGGAAATAATCCTGAGAGGCCAGCCTTCCTGCACAAAAGCCTACAAGAAAGAAACAAATGAGACCAAGGAAACCAACT GTACTGATGAGAGAATAACCTGGGTCTCCAGACCTGATCAGAATTCGGACCTTCAGATTCGTACCGTGGCCATCACTCATGACGGGTATTACAGATGCAT AATGGTAACACCTGATGGGAATTTCCATCGTGGATATCACCTCCAAGTGTTAGTTACACCTGAAGTGACCCTGTTTCAAAACAGGAATAGAACTGCAGTA TGCAAGGCAGTTGCAGGGAAGCCAGCTGCGCATATCTCCTGGATCCCAGAGGGCGATTGTGCCACTAAGCAAGAATACTGGAGCAATGGCACAGTGACTG TTAAGAGTACATGCCACTGGGAGGTCCACAATGTGTCTACCGTGACCTGCCACGTCTCCCATTTGACTGGCAACAAGAGTCTGTACATAGAGCTACTTCC TGTTCCAGGTGCCAAAAAATCAGCAAAATTATATATTCCATATATCATCCTTACTATTATTATTTTGACCATCGTGGGATTCATTTGGTTGTTGAAAGTC AATGGCTGCAGAAAATATAAATTGAATAAAACAGAATCTACTCCAGTTGTTGAGGAGGATGAAATGCAGCCCTATGCCAGCTACACAGAGAAGAACAATC CTCTCTATGATACTACAAACAAGGTGAAGGCATCTGAGGCATTACAAAGTGAAGTTGACACAGACCTCCATACTTTATAAGTTGTTGGACTCTAGTACCA AGAAACAACAACAAACGAGATACATTATAATTACTGTCTGATTTTCTTACAGTTCTAGAATGAAGACTTATATTGAAATTAGGTTTTCCAAGGTTCTTAG AAGACATTTTAATGGATTCTCATTCATACCCTTGTATAATTGGAATTTTTGATTCTTAGCTGCTACCAGCTAGTTCTCTGAAGAACTGATGTTATTACAA AGAAAATACATGCCCATGACCAAATATTCAAATTGTGCAGGACAGTAAATAATGAAAACCAAATTTCCTCAAGAAATAACTGAAGAAGGAGCAAGTGTGA ACAGTTTCTTGTGTATCCTTTCAGAATATTTTAATGTACATATGACATGTGTATATGCCTATGGTATATGTGTCAATTTATGTGTCCCCTTACATATACA TGCACATATCTTTGTCAAGGCACCAGTGGGAACAATACACTGCATTACTGTTCTATACATATGAAAACCTAATAATATAAGTCTTAGAGATCATTTTATA TCATGACAAGTAGAGCTACCTCATTCTTTTTAATGGTTATATAAAATTCCATTGTATAGTTATATCATTATTTAATTAAAAACAACCCTAATGATGGATA TTTAGATTCTTTTAAGTTTTGTTTATTTCTTTTAAGTTTTGTTTGTGGTATAAACAATACCACATAGAATGTTTCTTGTGCATATATCTCTTTGTTTTTG AGTATATCTGTAGGATAACTTTCTTGAGTGGAATTGTCAGGTCAAAGGGTTTGTGCATTTTACTATTGATATATATGTTAAATTGTGTCAAATATATATG TCAAATTCCCTCCAACATTGTTTAAATGTGCCTTTCCCTAAATTTCTATTTTAATAACTGTACTATTCCTGCTTCTACAGTTGCCACTTTCTCTTTTTAA TCAACCAGATTAAATATGATGTGAGATTATAATAAGAATTATACTATTTAATAAAAATGGATTTATATTTTT

refseq_CD200R1.F2 (forward primer)
refseq_CD200R1.R2 (reverse primer)
Single exon skipping

Frame 0

IAVSSSREKLLFVQVTNQAKPHRREGRG*KEGS APLLMG*EDPVLRS*PERVSPCAQFLLYLCGGKV LSEGQKKRKQKCSALGELLT*GYC*F*LSS*WP KRRVLLNQTTH*CCKLARRIML*LQAVYVWMKN RLHRTTRKYSQKLTLHGL*RWLQMLCFVALLSH* EI*S**HGK*S*EASLPAQKPTRKKQMRPRKPT VLMRE*PGSPDLIRIRTFRFVPWPSLMTGITDA *W*HLMGISIVDITSKC*LHLK*PCFKTGIELQY ARQLQGSQLRISPGSQRAIVPLSKNTGAMAQ*L LRVHATGRSTMCLP*PATSPI*LATRVCT*SYF LFQVPKNQQNYIFHISSLLLLF*PSWDSFGC*KS MAAENIN*IKQNLLQLLRRMKCSPMPATQRRTI LSMILQTR*RHLRHYKVKLTQTSILYKLLDSST KKQQQTRYIIITV*FSYSSRMKTYIEIRFSKVLR RHFNGFSFIPLYNWNF*FLAATS*FSEELMLLQ RKYMPMTKYSNCAGQ*IMKTKFPQEITEEGASV NSFLCILSEYFNVHMTCVYAYGICVNLCVPLHIH AHIFVKAPVGTIHCITVLYI*KPNNISLRDHFI S*QVELPHSF*WLYKIPLYSYIII*LKTTLMMD I*ILLSFVYFF*VLFVV*TIPHRMFLVHISLCF* VYL*DNFLEWNCQVKGFVHFTIDIYVKLCQIYM SNSLQHCLNVPFPKFLF**LYYSCFYSCHFLFL INQIKYDVRL**ELYYLIKMDLYF

Frame 1

LLCQVPEKSFCSSKLLTRLNHIDVKEGARRKGV PHC*WGKRILY*EVDQRGSHHAHSSFCTCVEEK Y*VKGRKRENRNALPLENC*PRATVDFDYLLSGR SGGCCSTKQLINAAN*QGESCFSFKQFMYG*KT DYTELLESTRRS*HFMACKDGYKCCALLPSYRI KKFDHNNMGNNPERPAFLHKSLQERNK*DQGNQL Y**ENNLGLQT*SEFGPSDSYRGHHS*RVLQMH NGNT*WEFPSWISPPSVSYT*SDPVSKQE*NCS MQGSCREASCAYLLDPRGRLCH*ARILEQWHSDC *EYMPLGGPQCVYRDLPRLPFDWQQESVHRATS CSRCQKISKIIYSIYHPYYYYFDHRGIHLVVES QWLQKI*IE*NRIYSSC*GG*NAALCQLHREEQS SL*YYKQGEGI*GITK*S*HRPPYFISCWTLVP RNNNKRDTL*LLSDFLTVLE*RLILKLGFPRFL EDILMDSHSYPCIIGIFDS*LLPASSLKN*CYYK ENTCP*PNIQIVQDSK**KPNFLKK*LKKEQV* TVSCVSFQNILMYI*HVYMPMVYVSIYVSPYIY MHISLSRHQWEQYTALLFYTYENLII*VLEIILY HDK*SYLILFNGYIKFHCIVISLFN*KQP**WI FRFF*VLFISFKFCLWYKQYHIECFLCIYLFVF EYICRITFLSGIVRSKGLCILLLIYMLNCVKYIC QIPSNIV*MCLSLNFYFNNCTIPASTVATFSF* STRLNMM*DYNKNYTI**KWIYIF

Frame 2

CCVKFQRKASVRPSY*PG*TT*T*RKGLEGREC PTVDGVRGSCTEKLTREGLTMRTVPSVPVWRKS TE*RAEKEKTEMLCPWRTANLGLLLILTIFLVA EAEGAAQPNNSLMLQTSKENHALASSSLCMDEKQ ITQNYSKVLAEVNTSWPVKMATNAVLCCPPIAL RNLIIITWEIILRGQPSCTKAYKKETNETKETN CTDERITWVSRPDQNSDLQIRTVAITHDGYYRCI MVTPDGNFHRGYHLQVLVTPEVTLFQNRNRTAV CKAVAGKPAAHISWIPEGDCATKQEYWSNGTVT VKSTCHWEVHNVSTVTCHVSHLTGNKSLYIELLP VPGAKKSAKLYIPYIILTIIILTIVGFIWLLKV NGCRKYKLNKTESTPVVEEDEMQPYASYTEKNN PLYDTTNKVKASEALQSEVDTDLHTL*VVGL*YQ ETTTNEIHYNYCLIFLQF*NEDLY*N*VFQGS* KTF*WILIHTLV*LEFLILSCYQLVL*RTDVIT KKIHAHDQIFKLCRTVNNENQISSRNN*RRSKCE QFLVYPFRIF*CTYDMCICLWYMCQFMCPLTYT CTYLCQGTSGNNTLHYCSIHMKT**YKS*RSFY IMTSRATSFFLMVI*NSIV*LYHYLIKNNPNDGY LDSFKFCLFLLSFVCGINNTT*NVSCAYISLFL SISVG*LS*VELSGQRVCAFYY*YIC*IVSNIY VKFPPTLFKCAFP*ISILITVLFLLLQLPLSLFN QPD*I*CEIIIRIILFNKNGFIF