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Sequences

Sequence NM_001291

GCTCACGGCGGCGGCGGCGGAGCGGAGAGGCCAGAGCCGGAGACCGAGCTGGGATCGGGCCCCGGGCGGGGGCGGTGCGAGCGGCGCCAAGCAGATCTTA GGGGCGGGGACGGAGCCGGGGCGGGCGGGACTGAAGCGGAGCCCGGGAACGGGGCGGGAGGTCCCAGGGTCCCGGGTTGGGGGGGTGGAGCAGCATTTCG TCGCCGCGGGGGTGCCGGGACTCCGGCCGCAGTGTCGCCGCCATCACGGACTTCCTGTGGGACAAGCGCACGGGCCTCGCCGCCAGAACGATGCCGCATC CTCGAAGGTACCACTCCTCAGAGCGAGGCAGCCGGGGGAGTTACCGTGAACACTATCGGAGCCGAAAGCATAAGCGACGAAGAAGTCGCTCCTGGTCAAG TAGTAGTGACCGGACACGACGGCGTCGGCGAGAGGACAGCTACCATGTCCGTTCTCGAAGCAGTTATGATGATCGTTCGTCCGACCGGAGGGTGTATGAC CGGCGATACTGTGGCAGCTACAGACGCAACGATTATAGCCGGGATCGGGGAGATGCCTACTATGACACAGACTATCGGCATTCCTATGAATATCAGCGGG AGAACAGCAGTTACCGCAGCCAGCGCAGCAGCCGGAGGAAGCACAGACGGCGGAGGAGGCGCAGCCGGACATTTAGCCGCTCATCTTCGATGAAATCGTT AGCACCTTAGGAGAGGGGACCTTCGGCCGAGTTGTACAATGTGTTGACCATCGCAGGGGTGGGGCTCGAGTTGCCCTGAAGATCATTAAGAATGTGGAGA AGTACAAGGAAGCAGCTCGACTTGAGATCAACGTGCTAGAGAAAATCAATGAGAAAGACCCTGACAACAAGAACCTCTGTGTCCAGATGTTTGACTGGTT TGACTACCATGGCCACATGTGTATCTCCTTTGAGCTTCTGGGCCTTAGCACCTTCGATTTCCTCAAAGACAACAACTACCTGCCCTACCCCATCCACCAA GTGCGCCACATGGCCTTCCAGCTGTGCCAGGCTGTCAAGTTCCTCCATGATAACAAGCTGACACATACAGACCTCAAGCCTGAAAATATTCTGTTTGTGA ATTCAGACTATGAGCTCACCTACAACCTAGAGAAGAAGCGAGATGAGCGCAGTGTGAAGAGCACAGCTGTGCGGGTGGTAGACTTTGGCAGTGCCACCTT TGACCATGAGCACCATAGCACCATTGTCTCCACTCGCCATTACCGAGCACCAGAAGTCATCCTTGAGTTGGGCTGGTCACAGCCTTGTGATGTGTGGAGT ATAGGCTGCATCATCTTTGAATACTATGTGGGATTCACCCTCTTCCAGACCCATGACAACAGAGAGCATCTAGCCATGATGGAAAGGATCTTGGGTCCTA TCCCTTCCCGGATGATCCGAAAGACAAGAAAGCAGAAATATTTTTACCGGGGTCGCCTGGATTGGGATGAGAACACATCAGCTGGGCGCTATGTTCGTGA GAACTGCAAACCGCTGCGGCGGTATCTGACCTCAGAGGCAGAGGAACACCACCAGCTCTTCGATCTGATTGAAAGCATGCTAGAGTATGAACCAGCTAAG CGGCTGACCTTGGGTGAAGCCCTTCAGCATCCTTTCTTCGCCCGCCTTCGGGCTGAGCCGCCCAACAAGTTGTGGGACTCCAGTCGGGATATCAGTCGGT GACGATCAGGCCCTGGGCCCCCCTGCATCTTTTATAGCAGTGGGTGTCCAGTCCAGGACACTGGTGCTTTTTTATACAAGAGAACGAGCCAGAGTTCACT CCTTCCTCCTGGCTCTCTATATACCTGTGAATATGTGAAATAGTGTAAATATGAAAGAACTTGTACCTATCACTTCAACCCCTGCCTTGTACATAATACT ATTCCATCCACACAGTTTCCACCCTCACCTGCCCCCTCATACGGAGTTGGATGGGGGCCGAGTGAGGTAACCAGGTGGCATCTACCCCATGTTTTATAAG GAATTTTGTACAGTCTTTGTGAAATAAAATAACGTGCTTCATTTGACCCCCA

refseq_CLK2.F1 (forward primer)
refseq_CLK2.R1 (reverse primer)
Single exon skipping

Frame 0

AHGGGGGAERPEPETELGSGPGRGRCERRQADL RGGDGAGAGGTEAEPGNGAGGPRVPGWGGGAAFR RRGGAGTPAAVSPPSRTSCGTSARASPPERCRI LEGTTPQSEAAGGVTVNTIGAESISDEEVAPGQ VVVTGHDGVGERTATMSVLEAVMMIVRPTGGCMT GDTVAATDATIIAGIGEMPTMTQTIGIPMNISG RTAVTAASAAAGGSTDGGGGAAGHLAAHLR*NR *HLRRGDLRPSCTMC*PSQGWGSSCPEDH*ECGE VQGSSST*DQRARENQ*ERP*QQEPLCPDV*LV *LPWPHVYLL*ASGP*HLRFPQRQQLPALPHPP SAPHGLPAVPGCQVPP**QADTYRPQA*KYSVCE FRL*AHLQPREEAR*AQCEEHSCAGGRLWQCHL *P*AP*HHCLHSPLPSTRSHP*VGLVTAL*CVE YRLHHL*ILCGIHPLPDP*QQRASSHDGKDLGSY PFPDDPKDKKAEIFLPGSPGLG*EHISWALCS* ELQTAAAVSDLRGRGTPPALRSD*KHARV*TS* AADLG*SPSASFLRPPSG*AAQQVVGLQSGYQSV TIRPWAPLHLL*QWVSSPGHWCFFIQENEPEFT PSSWLSIYL*ICEIV*I*KNLYLSLQPLPCT*Y YSIHTVSTLTCPLIRSWMGAE*GNQVASTPCFIR NFVQSL*NKITCFI*PP

Frame 1

LTAAAAERRGQSRRPSWDRAPGGGGASGAKQIL GAGTEPGRAGLKRSPGTGREVPGSRVGGVEQHF VAAGVPGLRPQCRRHHGLPVGQAHGPRRQNDAAS SKVPLLRARQPGELP*TLSEPKA*ATKKSLLVK ***PDTTASARGQLPCPFSKQL**SFVRPEGV* PAILWQLQTQRL*PGSGRCLL*HRLSAFL*ISAG EQQLPQPAQQPEEAQTAEEAQPDI*PLIFDEIV STLGEGTFGRVVQCVDHRRGGARVALKIIKNVE KYKEAARLEINVLEKINEKDPDNKNLCVQMFDWF DYHGHMCISFELLGLSTFDFLKDNNYLPYPIHQ VRHMAFQLCQAVKFLHDNKLTHTDLKPENILFV NSDYELTYNLEKKRDERSVKSTAVRVVDFGSATF DHEHHSTIVSTRHYRAPEVILELGWSQPCDVWS IGCIIFEYYVGFTLFQTHDNREHLAMMERILGP IPSRMIRKTRKQKYFYRGRLDWDENTSAGRYVRE NCKPLRRYLTSEAEEHHQLFDLIESMLEYEPAK RLTLGEALQHPFFARLRAEPPNKLWDSSRDISR *RSGPGPPCIFYSSGCPVQDTGAFLYKRTSQSSL LPPGSLYTCEYVK*CKYERTCTYHFNPCLVHNT IPSTQFPPSPAPSYGVGWGPSEVTRWHLPHVL* GILYSLCEIK*RASFDP

Frame 2

SRRRRRSGEARAGDRAGIGPRAGAVRAAPSRS* GRGRSRGGRD*SGARERGGRSQGPGLGGWSSIS SPRGCRDSGRSVAAITDFLWDKRTGLAARTMPH PRRYHSSERGSRGSYREHYRSRKHKRRRSRSWSS SSDRTRRRRREDSYHVRSRSSYDDRSSDRRVYD RRYCGSYRRNDYSRDRGDAYYDTDYRHSYEYQR ENSSYRSQRSSRRKHRRRRRRSRTFSRSSSMKSL AP*ERGPSAELYNVLTIAGVGLELP*RSLRMWR STRKQLDLRSTC*RKSMRKTLTTRTSVSRCLTG LTTMATCVSPLSFWALAPSISSKTTTTCPTPSTK CATWPSSCARLSSSSMITS*HIQTSSLKIFCL* IQTMSSPTT*RRSEMSAV*RAQLCGW*TLAVPP LTMSTIAPLSPLAITEHQKSSLSWAGHSLVMCGV *AASSLNTMWDSPSSRPMTTESI*P*WKGSWVL SLPG*SERQESRNIFTGVAWIGMRTHQLGAMFV RTANRCGGI*PQRQRNTTSSSI*LKAC*SMNQLS G*PWVKPFSILSSPAFGLSRPTSCGTPVGISVG DDQALGPPASFIAVGVQSRTLVLFYTRERARVH SFLLALYIPVNM*NSVNMKELVPITSTPALYIIL FHPHSFHPHLPPHTELDGGRVR*PGGIYPMFYK EFCTVFVK*NNVLHLTP

Sequence NM_003993

GCTCACGGCGGCGGCGGCGGAGCGGAGAGGCCAGAGCCGGAGACCGAGCTGGGATCGGGCCCCGGGCGGGGGCGGTGCGAGCGGCGCCAAGCAGATCTTA GGGGCGGGGACGGAGCCGGGGCGGGCGGGACTGAAGCGGAGCCCGGGAACGGGGCGGGAGGTCCCAGGGTCCCGGGTTGGGGGGGTGGAGCAGCATTTCG TCGCCGCGGGGGTGCCGGGACTCCGGCCGCAGTGTCGCCGCCATCACGGACTTCCTGTGGGACAAGCGCACGGGCCTCGCCGCCAGAACGATGCCGCATC CTCGAAGGTACCACTCCTCAGAGCGAGGCAGCCGGGGGAGTTACCGTGAACACTATCGGAGCCGAAAGCATAAGCGACGAAGAAGTCGCTCCTGGTCAAG TAGTAGTGACCGGACACGACGGCGTCGGCGAGAGGACAGCTACCATGTCCGTTCTCGAAGCAGTTATGATGATCGTTCGTCCGACCGGAGGGTGTATGAC CGGCGATACTGTGGCAGCTACAGACGCAACGATTATAGCCGGGATCGGGGAGATGCCTACTATGACACAGACTATCGGCATTCCTATGAATATCAGCGGG AGAACAGCAGTTACCGCAGCCAGCGCAGCAGCCGGAGGAAGCACAGACGGCGGAGGAGGCGCAGCCGGACATTTAGCCGCTCATCTTCGCACAGCAGCCG GAGAGCCAAGAGTGTAGAGGACGACGCTGAGGGCCACCTCATCTACCACGTCGGGGACTGGCTACAAGAGCGATATGAAATCGTTAGCACCTTAGGAGAG GGGACCTTCGGCCGAGTTGTACAATGTGTTGACCATCGCAGGGGTGGGGCTCGAGTTGCCCTGAAGATCATTAAGAATGTGGAGAAGTACAAGGAAGCAG CTCGACTTGAGATCAACGTGCTAGAGAAAATCAATGAGAAAGACCCTGACAACAAGAACCTCTGTGTCCAGATGTTTGACTGGTTTGACTACCATGGCCA CATGTGTATCTCCTTTGAGCTTCTGGGCCTTAGCACCTTCGATTTCCTCAAAGACAACAACTACCTGCCCTACCCCATCCACCAAGTGCGCCACATGGCC TTCCAGCTGTGCCAGGCTGTCAAGTTCCTCCATGATAACAAGCTGACACATACAGACCTCAAGCCTGAAAATATTCTGTTTGTGAATTCAGACTATGAGC TCACCTACAACCTAGAGAAGAAGCGAGATGAGCGCAGTGTGAAGAGCACAGCTGTGCGGGTGGTAGACTTTGGCAGTGCCACCTTTGACCATGAGCACCA TAGCACCATTGTCTCCACTCGCCATTACCGAGCACCAGAAGTCATCCTTGAGTTGGGCTGGTCACAGCCTTGTGATGTGTGGAGTATAGGCTGCATCATC TTTGAATACTATGTGGGATTCACCCTCTTCCAGACCCATGACAACAGAGAGCATCTAGCCATGATGGAAAGGATCTTGGGTCCTATCCCTTCCCGGATGA TCCGAAAGACAAGAAAGCAGAAATATTTTTACCGGGGTCGCCTGGATTGGGATGAGAACACATCAGCTGGGCGCTATGTTCGTGAGAACTGCAAACCGCT GCGGCGGTATCTGACCTCAGAGGCAGAGGAACACCACCAGCTCTTCGATCTGATTGAAAGCATGCTAGAGTATGAACCAGCTAAGCGGCTGACCTTGGGT GAAGCCCTTCAGCATCCTTTCTTCGCCCGCCTTCGGGCTGAGCCGCCCAACAAGTTGTGGGACTCCAGTCGGGATATCAGTCGGTGACGATCAGGCCCTG GGCCCCCCTGCATCTTTTATAGCAGTGGGTGTCCAGTCCAGGACACTGGTGCTTTTTTATACAAGAGAACGAGCCAGAGTTCACTCCTTCCTCCTGGCTC TCTATATACCTGTGAATATGTGAAATAGTGTAAATATGAAAGAACTTGTACCTATCACTTCAACCCCTGCCTTGTACATAATACTATTCCATCCACACAG TTTCCACCCTCACCTGCCCCCTCATACGGAGTTGGATGGGGGCCGAGTGAGGTAACCAGGTGGCATCTACCCCATGTTTTATAAGGAATTTTGTACAGTC TTTGTGAAATAAAATAACGTGCTTCATTTGACCCCCA

refseq_CLK2.F1 (forward primer)
refseq_CLK2.R1 (reverse primer)
Single exon skipping

Frame 0

AHGGGGGAERPEPETELGSGPGRGRCERRQADL RGGDGAGAGGTEAEPGNGAGGPRVPGWGGGAAFR RRGGAGTPAAVSPPSRTSCGTSARASPPERCRI LEGTTPQSEAAGGVTVNTIGAESISDEEVAPGQ VVVTGHDGVGERTATMSVLEAVMMIVRPTGGCMT GDTVAATDATIIAGIGEMPTMTQTIGIPMNISG RTAVTAASAAAGGSTDGGGGAAGHLAAHLRTAA GEPRV*RTTLRATSSTTSGTGYKSDMKSLAP*ER GPSAELYNVLTIAGVGLELP*RSLRMWRSTRKQ LDLRSTC*RKSMRKTLTTRTSVSRCLTGLTTMA TCVSPLSFWALAPSISSKTTTTCPTPSTKCATWP SSCARLSSSSMITS*HIQTSSLKIFCL*IQTMS SPTT*RRSEMSAV*RAQLCGW*TLAVPPLTMST IAPLSPLAITEHQKSSLSWAGHSLVMCGV*AASS LNTMWDSPSSRPMTTESI*P*WKGSWVLSLPG* SERQESRNIFTGVAWIGMRTHQLGAMFVRTANR CGGI*PQRQRNTTSSSI*LKAC*SMNQLSG*PWV KPFSILSSPAFGLSRPTSCGTPVGISVGDDQAL GPPASFIAVGVQSRTLVLFYTRERARVHSFLLA LYIPVNM*NSVNMKELVPITSTPALYIILFHPHS FHPHLPPHTELDGGRVR*PGGIYPMFYKEFCTV FVK*NNVLHLTP

Frame 1

LTAAAAERRGQSRRPSWDRAPGGGGASGAKQIL GAGTEPGRAGLKRSPGTGREVPGSRVGGVEQHF VAAGVPGLRPQCRRHHGLPVGQAHGPRRQNDAAS SKVPLLRARQPGELP*TLSEPKA*ATKKSLLVK ***PDTTASARGQLPCPFSKQL**SFVRPEGV* PAILWQLQTQRL*PGSGRCLL*HRLSAFL*ISAG EQQLPQPAQQPEEAQTAEEAQPDI*PLIFAQQP ESQECRGRR*GPPHLPRRGLATRAI*NR*HLRR GDLRPSCTMC*PSQGWGSSCPEDH*ECGEVQGSS ST*DQRARENQ*ERP*QQEPLCPDV*LV*LPWP HVYLL*ASGP*HLRFPQRQQLPALPHPPSAPHG LPAVPGCQVPP**QADTYRPQA*KYSVCEFRL*A HLQPREEAR*AQCEEHSCAGGRLWQCHL*P*AP *HHCLHSPLPSTRSHP*VGLVTAL*CVEYRLHH L*ILCGIHPLPDP*QQRASSHDGKDLGSYPFPDD PKDKKAEIFLPGSPGLG*EHISWALCS*ELQTA AAVSDLRGRGTPPALRSD*KHARV*TS*AADLG *SPSASFLRPPSG*AAQQVVGLQSGYQSVTIRPW APLHLL*QWVSSPGHWCFFIQENEPEFTPSSWL SIYL*ICEIV*I*KNLYLSLQPLPCT*YYSIHT VSTLTCPLIRSWMGAE*GNQVASTPCFIRNFVQS L*NKITCFI*PP

Frame 2

SRRRRRSGEARAGDRAGIGPRAGAVRAAPSRS* GRGRSRGGRD*SGARERGGRSQGPGLGGWSSIS SPRGCRDSGRSVAAITDFLWDKRTGLAARTMPH PRRYHSSERGSRGSYREHYRSRKHKRRRSRSWSS SSDRTRRRRREDSYHVRSRSSYDDRSSDRRVYD RRYCGSYRRNDYSRDRGDAYYDTDYRHSYEYQR ENSSYRSQRSSRRKHRRRRRRSRTFSRSSSHSSR RAKSVEDDAEGHLIYHVGDWLQERYEIVSTLGE GTFGRVVQCVDHRRGGARVALKIIKNVEKYKEA ARLEINVLEKINEKDPDNKNLCVQMFDWFDYHGH MCISFELLGLSTFDFLKDNNYLPYPIHQVRHMA FQLCQAVKFLHDNKLTHTDLKPENILFVNSDYE LTYNLEKKRDERSVKSTAVRVVDFGSATFDHEHH STIVSTRHYRAPEVILELGWSQPCDVWSIGCII FEYYVGFTLFQTHDNREHLAMMERILGPIPSRM IRKTRKQKYFYRGRLDWDENTSAGRYVRENCKPL RRYLTSEAEEHHQLFDLIESMLEYEPAKRLTLG EALQHPFFARLRAEPPNKLWDSSRDISR*RSGP GPPCIFYSSGCPVQDTGAFLYKRTSQSSLLPPGS LYTCEYVK*CKYERTCTYHFNPCLVHNTIPSTQ FPPSPAPSYGVGWGPSEVTRWHLPHVL*GILYS LCEIK*RASFDP