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Sequence NM_001025161
GTGCTGAGAGTGTCCTGCCTGGTCCTCTGTGCCTGGTGGGGTGGGGGTGCCAGGTGTGTCCAGAGGAGCCCATTTGGTAGTGAGGCAGGTATGGGGCTAGAAGCACTGGTGCCCCTGGCCGTGATAGTGGCCATCTTCCTGCTCCTGGTGGACCTGATGCACCGGCGCCAACGCTGGGCTGCACGCTACCCACCAGGCCC
CCTGCCACTGCCCGGGCTGGGCAACCTGCTGCATGTGGACTTCCAGAACACACCATACTGCTTCGACCAGTTGCGGCGCCGCTTCGGGGACGTGTTCAGC
CTGCAGCTGGCCTGGACGCCGGTGGTCGTGCTCAATGGGCTGGCGGCCGTGCGCGAGGCGCTGGTGACCCACGGCGAGGACACCGCCGACCGCCCGCCTG
TGCCCATCACCCAGATCCTGGGTTTCGGGCCGCGTTCCCAAGGACGCCCCTTTCGCCCCAACGGTCTCTTGGACAAAGCCGTGAGCAACGTGATCGCCTC
CCTCACCTGCGGGCGCCGCTTCGAGTACGACGACCCTCGCTTCCTCAGGCTGCTGGACCTAGCTCAGGAGGGACTGAAGGAGGAGTCGGGCTTTCTGCGC
GAGGTGCTGAATGCTGTCCCCGTCCTCCTGCATATCCCAGCGCTGGCTGGCAAGGTCCTACGCTTCCAAAAGGCTTTCCTGACCCAGCTGGATGAGCTGC
TAACTGAGCACAGGATGACCTGGGACCCAGCCCAGCCCCCCCGAGACCTGACTGAGGCCTTCCTGGCAGAGATGGAGAAGGCCAAGGGGAACCCTGAGAG
CAGCTTCAATGATGAGAACCTGTGCATAGTGGTGGCTGACCTGTTCTCTGCCGGGATGGTGACCACCTCGACCACGCTGGCCTGGGGCCTCCTGCTCATG
ATCCTACATCCGGATGTGCAGCGCCGTGTCCAACAGGAGATCGACGACGTGATAGGGCAGGTGCGGCGACCAGAGATGGGTGACCAGGCTCACATGCCCT
ACACCACTGCCGTGATTCATGAGGTGCAGCGCTTTGGGGACATCGTCCCCCTGGGTGTGACCCATATGACATCCCGTGACATCGAAGTACAGGGCTTCCG
CATCCCTAAGGGAACGACACTCATCACCAACCTGTCATCGGTGCTGAAGGATGAGGCCGTCTGGGAGAAGCCCTTCCGCTTCCACCCCGAACACTTCCTG
GATGCCCAGGGCCACTTTGTGAAGCCGGAGGCCTTCCTGCCTTTCTCAGCAGGCCGCCGTGCATGCCTCGGGGAGCCCCTGGCCCGCATGGAGCTCTTCC
TCTTCTTCACCTCCCTGCTGCAGCACTTCAGCTTCTCGGTGCCCACTGGACAGCCCCGGCCCAGCCACCATGGTGTCTTTGCTTTCCTGGTGACCCCATC
CCCCTATGAGCTTTGTGCTGTGCCCCGCTAGAATGGGGTACCTAGTCCCCAGCCTGCTCCCTAGCCAGAGGCTCTAATGTACAATAAAGCAATGTGGTAG
TTCCAA
- refseq_CYP2D6.F1 (forward primer)
- refseq_CYP2D6.R1 (reverse primer)
- Single exon skipping
Frame 0
VLRVSCLVLCAWWGGGARCVQRSPFGSEAGMGLEALVPLAVIVAIFLLLVDLMHRRQRWAARYPPGP
LPLPGLGNLLHVDFQNTPYCFDQLRRRFGDVFS
LQLAWTPVVVLNGLAAVREALVTHGEDTADRPP
VPITQILGFGPRSQGRPFRPNGLLDKAVSNVIAS
LTCGRRFEYDDPRFLRLLDLAQEGLKEESGFLR
EVLNAVPVLLHIPALAGKVLRFQKAFLTQLDEL
LTEHRMTWDPAQPPRDLTEAFLAEMEKAKGNPES
SFNDENLCIVVADLFSAGMVTTSTTLAWGLLLM
ILHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMP
YTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFR
IPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFL
DAQGHFVKPEAFLPFSAGRRACLGEPLARMELF
LFFTSLLQHFSFSVPTGQPRPSHHGVFAFLVTPS
PYELCAVPR*NGVPSPQPAP*PEALMYNKAMW*
FQ
Frame 1
C*ECPAWSSVPGGVGVPGVSRGAHLVVRQVWG*KHWCPWP**WPSSCSWWT*CTGANAGLHATHQA
PCHCPGWATCCMWTSRTHHTASTSCGAASGTCSA
CSWPGRRWSCSMGWRPCARRW*PTARTPPTARL
CPSPRSWVSGRVPKDAPFAPTVSWTKP*AT*SP
PSPAGAASSTTTLASSGCWT*LRRD*RRSRAFCA
RC*MLSPSSCISQRWLARSYASKRLS*PSWMSC
*LSTG*PGTQPSPPET*LRPSWQRWRRPRGTLR
AASMMRTCA*WWLTCSLPGW*PPRPRWPGASCS*
SYIRMCSAVSNRRSTT**GRCGDQRWVTRLTCP
TPLP*FMRCSALGTSSPWV*PI*HPVTSKYRAS
ASLRERHSSPTCHRC*RMRPSGRSPSASTPNTSW
MPRATL*SRRPSCLSQQAAVHASGSPWPAWSSS
SSSPPCCSTSASRCPLDSPGPATMVSLLSW*PH
PPMSFVLCPARMGYLVPSLLPSQRL*CTIKQCGS
S
Frame 2
AESVLPGPLCLVGWGCQVCPEEPIW**GRYGARSTGAPGRDSGHLPAPGGPDAPAPTLGCTLPTRP
PATARAGQPAACGLPEHTILLRPVAAPLRGRVQ
PAAGLDAGGRAQWAGGRARGAGDPRRGHRRPPAC
AHHPDPGFRAAFPRTPLSPQRSLGQSREQRDRL
PHLRAPLRVRRPSLPQAAGPSSGGTEGGVGLSA
RGAECCPRPPAYPSAGWQGPTLPKGFPDPAG*AA
N*AQDDLGPSPAPPRPD*GLPGRDGEGQGEP*E
QLQ**EPVHSGG*PVLCRDGDHLDHAGLGPPAH
DPTSGCAAPCPTGDRRRDRAGAATRDG*PGSHAL
HHCRDS*GAALWGHRPPGCDPYDIP*HRSTGLP
HP*GNDTHHQPVIGAEG*GRLGEALPLPPRTLP
GCPGPLCEAGGLPAFLSRPPCMPRGAPGPHGALP
LLHLPAAALQLLGAHWTAPAQPPWCLCFPGDPI
PL*ALCCAPLEWGT*SPACSLARGSNVQ*SNVV
VP
Sequence NM_000106
GTGCTGAGAGTGTCCTGCCTGGTCCTCTGTGCCTGGTGGGGTGGGGGTGCCAGGTGTGTCCAGAGGAGCCCATTTGGTAGTGAGGCAGGTATGGGGCTAGAAGCACTGGTGCCCCTGGCCGTGATAGTGGCCATCTTCCTGCTCCTGGTGGACCTGATGCACCGGCGCCAACGCTGGGCTGCACGCTACCCACCAGGCCC
CCTGCCACTGCCCGGGCTGGGCAACCTGCTGCATGTGGACTTCCAGAACACACCATACTGCTTCGACCAGTTGCGGCGCCGCTTCGGGGACGTGTTCAGC
CTGCAGCTGGCCTGGACGCCGGTGGTCGTGCTCAATGGGCTGGCGGCCGTGCGCGAGGCGCTGGTGACCCACGGCGAGGACACCGCCGACCGCCCGCCTG
TGCCCATCACCCAGATCCTGGGTTTCGGGCCGCGTTCCCAAGGGGTGTTCCTGGCGCGCTATGGGCCCGCGTGGCGCGAGCAGAGGCGCTTCTCCGTCTC
CACCTTGCGCAACTTGGGCCTGGGCAAGAAGTCGCTGGAGCAGTGGGTGACCGAGGAGGCCGCCTGCCTTTGTGCCGCCTTCGCCAACCACTCCGGACGC
CCCTTTCGCCCCAACGGTCTCTTGGACAAAGCCGTGAGCAACGTGATCGCCTCCCTCACCTGCGGGCGCCGCTTCGAGTACGACGACCCTCGCTTCCTCA
GGCTGCTGGACCTAGCTCAGGAGGGACTGAAGGAGGAGTCGGGCTTTCTGCGCGAGGTGCTGAATGCTGTCCCCGTCCTCCTGCATATCCCAGCGCTGGC
TGGCAAGGTCCTACGCTTCCAAAAGGCTTTCCTGACCCAGCTGGATGAGCTGCTAACTGAGCACAGGATGACCTGGGACCCAGCCCAGCCCCCCCGAGAC
CTGACTGAGGCCTTCCTGGCAGAGATGGAGAAGGCCAAGGGGAACCCTGAGAGCAGCTTCAATGATGAGAACCTGTGCATAGTGGTGGCTGACCTGTTCT
CTGCCGGGATGGTGACCACCTCGACCACGCTGGCCTGGGGCCTCCTGCTCATGATCCTACATCCGGATGTGCAGCGCCGTGTCCAACAGGAGATCGACGA
CGTGATAGGGCAGGTGCGGCGACCAGAGATGGGTGACCAGGCTCACATGCCCTACACCACTGCCGTGATTCATGAGGTGCAGCGCTTTGGGGACATCGTC
CCCCTGGGTGTGACCCATATGACATCCCGTGACATCGAAGTACAGGGCTTCCGCATCCCTAAGGGAACGACACTCATCACCAACCTGTCATCGGTGCTGA
AGGATGAGGCCGTCTGGGAGAAGCCCTTCCGCTTCCACCCCGAACACTTCCTGGATGCCCAGGGCCACTTTGTGAAGCCGGAGGCCTTCCTGCCTTTCTC
AGCAGGCCGCCGTGCATGCCTCGGGGAGCCCCTGGCCCGCATGGAGCTCTTCCTCTTCTTCACCTCCCTGCTGCAGCACTTCAGCTTCTCGGTGCCCACT
GGACAGCCCCGGCCCAGCCACCATGGTGTCTTTGCTTTCCTGGTGACCCCATCCCCCTATGAGCTTTGTGCTGTGCCCCGCTAGAATGGGGTACCTAGTC
CCCAGCCTGCTCCCTAGCCAGAGGCTCTAATGTACAATAAAGCAATGTGGTAGTTCCAA
- refseq_CYP2D6.F1 (forward primer)
- refseq_CYP2D6.R1 (reverse primer)
- Single exon skipping
Frame 0
VLRVSCLVLCAWWGGGARCVQRSPFGSEAGMGLEALVPLAVIVAIFLLLVDLMHRRQRWAARYPPGP
LPLPGLGNLLHVDFQNTPYCFDQLRRRFGDVFS
LQLAWTPVVVLNGLAAVREALVTHGEDTADRPP
VPITQILGFGPRSQGVFLARYGPAWREQRRFSVS
TLRNLGLGKKSLEQWVTEEAACLCAAFANHSGR
PFRPNGLLDKAVSNVIASLTCGRRFEYDDPRFL
RLLDLAQEGLKEESGFLREVLNAVPVLLHIPALA
GKVLRFQKAFLTQLDELLTEHRMTWDPAQPPRD
LTEAFLAEMEKAKGNPESSFNDENLCIVVADLF
SAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDD
VIGQVRRPEMGDQAHMPYTTAVIHEVQRFGDIV
PLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVL
KDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFS
AGRRACLGEPLARMELFLFFTSLLQHFSFSVPT
GQPRPSHHGVFAFLVTPSPYELCAVPR*NGVPS
PQPAP*PEALMYNKAMW*FQ
Frame 1
C*ECPAWSSVPGGVGVPGVSRGAHLVVRQVWG*KHWCPWP**WPSSCSWWT*CTGANAGLHATHQA
PCHCPGWATCCMWTSRTHHTASTSCGAASGTCSA
CSWPGRRWSCSMGWRPCARRW*PTARTPPTARL
CPSPRSWVSGRVPKGCSWRAMGPRGASRGASPS
PPCATWAWARSRWSSG*PRRPPAFVPPSPTTPDA
PFAPTVSWTKP*AT*SPPSPAGAASSTTTLASS
GCWT*LRRD*RRSRAFCARC*MLSPSSCISQRW
LARSYASKRLS*PSWMSC*LSTG*PGTQPSPPET
*LRPSWQRWRRPRGTLRAASMMRTCA*WWLTCS
LPGW*PPRPRWPGASCS*SYIRMCSAVSNRRST
T**GRCGDQRWVTRLTCPTPLP*FMRCSALGTSS
PWV*PI*HPVTSKYRASASLRERHSSPTCHRC*
RMRPSGRSPSASTPNTSWMPRATL*SRRPSCLS
QQAAVHASGSPWPAWSSSSSSPPCCSTSASRCPL
DSPGPATMVSLLSW*PHPPMSFVLCPARMGYLV
PSLLPSQRL*CTIKQCGSS
Frame 2
AESVLPGPLCLVGWGCQVCPEEPIW**GRYGARSTGAPGRDSGHLPAPGGPDAPAPTLGCTLPTRP
PATARAGQPAACGLPEHTILLRPVAAPLRGRVQ
PAAGLDAGGRAQWAGGRARGAGDPRRGHRRPPAC
AHHPDPGFRAAFPRGVPGALWARVARAEALLRL
HLAQLGPGQEVAGAVGDRGGRLPLCRLRQPLRT
PLSPQRSLGQSREQRDRLPHLRAPLRVRRPSLPQ
AAGPSSGGTEGGVGLSARGAECCPRPPAYPSAG
WQGPTLPKGFPDPAG*AAN*AQDDLGPSPAPPR
PD*GLPGRDGEGQGEP*EQLQ**EPVHSGG*PVL
CRDGDHLDHAGLGPPAHDPTSGCAAPCPTGDRR
RDRAGAATRDG*PGSHALHHCRDS*GAALWGHR
PPGCDPYDIP*HRSTGLPHP*GNDTHHQPVIGAE
G*GRLGEALPLPPRTLPGCPGPLCEAGGLPAFL
SRPPCMPRGAPGPHGALPLLHLPAAALQLLGAH
WTAPAQPPWCLCFPGDPIPL*ALCCAPLEWGT*S
PACSLARGSNVQ*SNVVVP
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