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Sequences

Sequence NM_152389

GTCCTGTATCTATGGAGACGGCAATATGGAGGCGATCTTACATTTCTTTGATTTCATCTGAACGTCCAGTTCACAATTGGAGCTCCATACTCAGAGTGCT CCCTTTGGACTGTGTCCCAAGGACATGATGCTCACCCAGGCTCCAAGCTCCGTCGTGAGGTCCAGGAACAGCAGGAACCACACCGTGAACTCTGGTGGAT CCTGCCTGAGTGCCAGCACAGTGGCCATCCCTGCCATCAACGACAGCAGTGCAGCCATGAGTGCCTGCAGCACCATCAGCGCCCAGCCCGCAAGCTCCAT GGACACTCAGATGCACTCCCCAAAGAAGCAGGAGAGAGTGAACAAGAGGGTCATCTGGGGCATTGAGGTGGCTGAGGAGCTGCATTGGAAAGGCTGGGAG CTAGGAAAGGAGACCACAAGGAATCTGGTTCTGAAAAATCGATCCTTGAAACTCCAGAAGATGAAGTACAGGTACCAGTATAAGGGATCAAGGACCCAGT GCCACAGCCTTGAGCCCCGAAAGCAGGCTCTCTTCAAAACAAAACAAAACAAACAAAAAAAACCTTTAACATGCCATATAAAAGCCAGTGAGTGTTTAAA ATACGTGCAGTATGAATAATTATGCAGCTATAATCCATTATTTTTCATTGTGGTATAGTGTCCCAATGTGTGCCTGTACCATAATGTATTCATCCAGAAT GAAGGAAGTTTGGGCTGTTTCTATTTGGGACTGTTGGCATTCGTGTATATGTGTCCAGTTACATAAGTACAAGAGTTTTTCTGGGGAATACCAGGTACTA TGAAGGCTCACGTGATTTTGGAGTCTTATGAAGGTTTTTTTTTTTTTTTTCCTGCGTAGTTGTTAAATTGGTGACCTTGCGGGATGGAACCTTCTATTCC ACCACCTTGCTCCACCTTCTGTCTTTTCTGGGGAATAGACGCAGGAGTAGAATTGCGGAGGCTTGGGCCATGTACCTGTTCACTTGCTGTAGATAAACCA AACTATTTCCCAAAGTGCATGGATTTCTTTAGACACCCACCAGCAGCATTAGAGAGTTCCCATTCCTCCACATCCTTACCAATAACTGCTATTGTCAGAA TTTAAAATTTTTGCCAGTAATGGTAACTTGTGGTTTTAATTTGCATTTCCCTGATTACTAATGAATGAGGATGAGTGTCTTTTTGTAGGTTATTGACACT TTGCATTTCTTCATGTGTGAAATTTATGATCAAGTCTGTGGCCATTTTTCTCTTACATTATCTTGTCTTTTTTCTTTTTGGTATAAGTTCTTATCCCAAT TACAAACTCTTTGCCAGTTATGCGTTGTGGATATCTTCTCTCATCTTATGATTTGTCTTTACTCCCTTTATTGTGTCTTTTGAAGAATAAAAGTTCAAAG TTGAATTTTAAAGGTATCAACTTTATCAGTCTTTTTATTTTATGATTGGTGCTTTTTTATGCTTCTCCTAAGAAGTCCTTCTCTACCCCTAGGTCATTAA GATATTTTCCTCTAGTATCTTCTAAAGACTTTATATTTTTGCCTTTTATATTTGTCTTTTGTCTATATGGAATTGATTTTTATGAATAGTAAGTCTTGAT AGCTGGTAGTATACGTCCTCCTACTTAATTCTTCTTCAAGATTGTCTTGGCTATTCTTGGCCCTCCCTTTGATCTCTTACATAAATATTCAAATCAGCTT ATCATACATGCACATAAAACACTTCTTGAGATTTTGATTGGGATTTAATTGGACCTATAGATGAATATGAGGAGAAATGATATCATTATAATATTGAGTC TTTTACTCCATGAACATGGGCTATTTCTGTATTCATTAGGTTATCTTTCCTGTCTCTCAATAGAGTGTAAAGTTTTCTCCATAGACATTTAGCACATCCT TAGTTAGATTTATTCATAAGTATTTTATATTTTTGCTGTTGTTATATATGACATATTTTTTAGTTGTTTTATTTCTGTTTGTTGCTAGTTTTTAAAATGT CATTTTTATATAGGTATTATGTTCAGTGATCTTGGCAAATCCTCTTATTCTAATAATTTATTTGTTAATTTTCTTGTTTTTTCATGCACACATTTGTATT TTAAATGGAAAATGACATTTTTTTTTCTTTCTAGTCCTTACACCTTTGGCTTTCCTTACTGCATTGTTAAATAGAAAAGTGTTGAACAGAAGTGGTTATA GAGGCATCTTTGTTTTGTTTATCATCTCAGAGTAAAGGACTGCAATGTTTCACTATTAA

refseq_CCDC108.F1 (forward primer)
refseq_CCDC108.R1 (reverse primer)
Single exon skipping

Frame 0

VLYLWRRQYGGDLTFL*FHLNVQFTIGAPYSEC SLWTVSQGHDAHPGSKLRREVQEQQEPHRELWWI LPECQHSGHPCHQRQQCSHECLQHHQRPARKLH GHSDALPKEAGESEQEGHLGH*GG*GAALERLG ARKGDHKESGSEKSILETPEDEVQVPV*GIKDPV PQP*APKAGSLQNKTKQTKKTFNMPYKSQ*VFK IRAV*IIMQL*SIIFHCGIVSQCVPVP*CIHPE *RKFGLFLFGTVGIRVYVSSYISTRVFLGNTRYY EGSRDFGVL*RFFFFFSCVVVKLVTLRDGTFYS TTLLHLLSFLGNRRRSRIAEAWAMYLFTCCR*T KLFPKVHGFL*TPTSSIREFPFLHILTNNCYCQN LKFLPVMVTCGFNLHFPDY**MRMSVFL*VIDT LHFFMCEIYDQVCGHFSLTLSCLFSFWYKFLSQ LQTLCQLCVVDIFSHLMICLYSLYCVF*RIKVQS *ILKVSTLSVFLFYDWCFFMLLLRSPSLPLGH* DIFL*YLLKTLYFCLLYLSFVYMELIFMNSKS* *LVVYVLLLNSSSRLSWLFLALPLISYINIQISL SYMHIKHFLRF*LGFNWTYR*I*GEMISL*Y*V FYSMNMGYFCIH*VIFPVSQ*SVKFSP*TFSTS LVRFIHKYFIFLLLLYMTYFLVVLFLFVASF*NV IFI*VLCSVILANPLILIIYLLIFLFFHAHICI LNGK*HFFFFLVLTPLAFLTALLNRKVLNRSGY RGIFVLFIISE*RTAMFHY*

Frame 1

SCIYGDGNMEAILHFFDFI*TSSSQLELHTQSA PFGLCPKDMMLTQAPSSVVRSRNSRNHTVNSGG SCLSASTVAIPAINDSSAAMSACSTISAQPASSM DTQMHSPKKQERVNKRVIWGIEVAEELHWKGWE LGKETTRNLVLKNRSLKLQKMKYRYQYKGSRTQ CHSLEPRKQALFKTKQNKQKKPLTCHIKASECLK YVQYE*LCSYNPLFFIVV*CPNVCLYHNVFIQN EGSLGCFYLGLLAFVYMCPVT*VQEFFWGIPGT MKAHVILESYEGFFFFFPA*LLNW*PCGMEPSIP PPCSTFCLFWGIDAGVELRRLGPCTCSLAVDKP NYFPKCMDFFRHPPAALESSHSSTSLPITAIVR I*NFCQ*W*LVVLICISLITNE*G*VSFCRLLTL CISSCVKFMIKSVAIFLLHYLVFFLFGISSYPN YKLFASYALWISSLIL*FVFTPFIVSFEE*KFK VEF*RYQLYQSFYFMIGAFLCFS*EVLLYP*VIK IFSSSIF*RLYIFAFYICLLSIWN*FL*IVSLD SW*YTSSYLILLQDCLGYSWPSL*SLT*IFKSA YHTCT*NTS*DFDWDLIGPIDEYEEK*YHYNIES FTP*TWAISVFIRLSFLSLNRV*SFLHRHLAHP *LDLFISILYFCCCYI*HIF*LFYFCLLLVFKM SFLYRYYVQ*SWQILLF**FIC*FSCFFMHTFVF *MENDIFFSF*SLHLWLSLLHC*IEKC*TEVVI EASLFCLSSQSKGLQCFTI

Frame 2

PVSMETAIWRRSYISLISSERPVHNWSSILRVL PLDCVPRT*CSPRLQAPS*GPGTAGTTP*TLVD PA*VPAQWPSLPSTTAVQP*VPAAPSAPSPQAP WTLRCTPQRSRRE*TRGSSGALRWLRSCIGKAGS *ERRPQGIWF*KIDP*NSRR*STGTSIRDQGPS ATALSPESRLSSKQNKTNKKNL*HAI*KPVSV* NTCSMNNYAAIIHYFSLWYSVPMCACTIMYSSRM KEVWAVSIWDCWHSCICVQLHKYKSFSGEYQVL *RLT*FWSLMKVFFFFFLRSC*IGDLAGWNLLF HHLAPPSVFSGE*TQE*NCGGLGHVPVHLL*INQ TISQSAWISLDTHQQH*RVPIPPHPYQ*LLLSE FKIFASNGNLWF*FAFP*LLMNEDECLFVGY*H FAFLHV*NL*SSLWPFFSYIILSFFFLV*VLIPI TNSLPVMRCGYLLSSYDLSLLPLLCLLKNKSSK LNFKGINFISLFIL*LVLFYASPKKSFSTPRSL RYFPLVSSKDFIFLPFIFVFCLYGIDFYE**VLI AGSIRPPT*FFFKIVLAILGPPFDLLHKYSNQL IIHAHKTLLEILIGI*LDL*MNMRRNDIIIILS LLLHEHGLFLYSLGYLSCLSIECKVFSIDI*HIL S*IYS*VFYIFAVVIYDIFFSCFISVCC*FLKC HFYIGIMFSDLGKSSYSNNLFVNFLVFSCTHLY FKWKMTFFFLSSPYTFGFPYCIVK*KSVEQKWL* RHLCFVYHLRVKDCNVSLL

Sequence NM_194302

GTCCTGTATCTATGGAGACGGCAATATGGAGGCGATCTTACATTTCTTTGATTTCATCTGAACGTCCAGTTCACAATTGGAGTGATGTTTACCTTAACCG GTTGTAGACTGGTGGAGAAAACCCAGAAGGTGGAGAATCCATCAGTCTCATTTGCCTCTTCTTTCCCCCTTATTCCTCTTCTCCTAAGAGGCAAGAGTGT TCAGAAGAAACAAGCAGAGAGTAAAAGCCAGATAAAGCTCCATACTCAGAGTGCTCCCTTTGGACTGTGTCCCAAGGACATGATGCTCACCCAGGCTCCA AGCTCCGTCGTGAGGTCCAGGAACAGCAGGAACCACACCGTGAACTCTGGTGGATCCTGCCTGAGTGCCAGCACAGTGGCCATCCCTGCCATCAACGACA GCAGTGCAGCCATGAGTGCCTGCAGCACCATCAGCGCCCAGCCCGCAAGCTCCATGGACACTCAGATGCACTCCCCAAAGAAGCAGGAGAGAGTGAACAA GAGGGTCATCTGGGGCATTGAGGTGGCTGAGGAGCTGCATTGGAAAGGCTGGGAGCTAGGAAAGGAGACCACAAGGAATCTGGTTCTGAAAAATCGATCC TTGAAACTCCAGAAGATGAAGTACAGGCCCCCCAAGACCAAGTTCTTCTTCACGGTCATCCCTCAGCCCATCTTCCTGAGCCCAGGCATAACCCTCACGC TCCCCATCGTCTTCCGGCCTCTGGAGGCGAAGGAGTACATGGACCAGCTGTGGTTTGAGAAAGCGGAGGGGATGTTCTGTGTCGGCCTACGGGCCACCCT GCCCTGCCACAGGCTGATCTGCCGCCCACCATCCCTGCAGCTGCCCATGTGTGCTGTGGGAGATACGACTGAGGCCTTTTTCTGCCTGGATAATGTGGGG GACCTGCCCACCTTCTTCACCTGGGAGTTCTCCAGCCCATTCCAGATGCTGCCCGCCACGGGGCTCCTGGAGCCAGGCCAGGCCTCTCAGATCAAGGTGA CCTTTCAGCCCCTTACAGCCGTCATCTACGAGGTGCAGGCCACGTGCTGGTACGGGGCGGGCAGCCGGCAGAGGAGCAGCATCCAGCTGCAGGCTGTGGC CAAGTGCGCCCAGCTGCTGGTGAGCATAAAGCACAAGTGCCCGGAGGACCAGGATGCCGAGGGCTTCCAGAAGCTGTTGTACTTTGGCTCTGTTGCTGTG GGCTGCACCTCGGAGAGGCAGATCAGGCTACACAACCCGTCGGCGGTAAATGCCCCCTTCAGGATTGAAATTTCCCCGGATGAACTGGCCGAAGACCAGG CCTTCTCATGCCCCACGGCCCATGGCATCGTGCTTCCGGGAGAGAAGAAATGTGTGTCGGTGTTCTTCCACCCCAAGACTCTGGACACCAGAACTGTGGA CTACTGCTCCATCATGCCTTCTGGCTGTGCCTCCAAGACCCTGCTTAAAGTCGTTGGTTTCTGTAGAGGCCCTGCTGTGTCCCTGCAGCACTACTGTGTC AACTTCAGCTGGGTCAACCTTGGGGAGCGCTCCGAGCAGCCCCTGTGGATTGAGAACCAATCGGACTGCACGGCCCACTTCCAGTTTGCCATCGACTGCT TGGAGAGTGTCTTTACCATCAGGCCTGCCTTTGGGACGCTGGTGGGCAAGGCCCGTATGACCCTGCACTGTGCCTTCCAGCCCACTCACCCCATCATCTG CTTTCGGCGTGTGGCCTGTCTCATCCACCACCAGGACCCACTGTTCCTGGACCTGATGGGGACCTGCCACTCGGACAGCACCAAGCCAGCCATCCTGAAG CCTCAGCACCTCACCTGGTACCGCACACACCTGGCCCGGGGCCTGACGCTCTACCCCCCTGACATCCTGGATGCCATGCTGAAGGAGAAGAAGCTGGCAC AGGACCAGAACGGGGCTCTCATGATTCCCATCCAGGATCTGGAGGACATGCCGGCCCCGCAGTACCCTTATATCCCCCCCATGACCGAGTTCTTCTTCGA CGGCACCAGCGACATAACCATCTTCCCCCCGCCCATCAGTGTAGAGCCTGTCGAGGTAGACTTCGGTGCCTGCCCAGGGCCTGAGGCCCCCAACCCTGTA CCCCTGTGCCTGATGAACCACACCAAGGGCAAGATCATGGTGGTCTGGACGCGAAGGTCTGACTGCCCCTTCTGGGTGACTCCAGAGAGCTGCGACGTGC CCCCACTCAAGTCCATGGCCATGCGCCTGCACTTCCAGCCGCCTCACCCCAACTGCCTTTACACGGTGGAGCTCGAAGCCTTCGCCATCTATAAGGTCCT GCAGAGCTACAGTAATATTGAGGAGGACTGCACCATGTGCCCATCCTGGTGCCTGACGGTGCGGGCACGAGGCCACAGCTATTTCGCTGGCTTTGAGCAC CACATCCCCCAGTATTCCCTAGATGTCCCCAAGCTATTTCCAGCAGTGTCCTCCGGTGAGCCCACCTACCGCAGCCTGCTCCTGGTCAACAAAGACTGCA AGCTGCTGACCTTCAGCCTGGCCCCCCAGAGAGGCTCAGACGTCATCCTTCGGCCCACTTCGGGCCTTGTGGCACCCGGGGCCCACCAGATCATCCTCAT CTGCACCTACCCTGAGGGCAGCTCCTGGAAGCAGCACACTTTCTATCTGCAGTGCAATGCTTCCCCCCAGTATCTCAAGGAGGTGAGCATGTACAGCCGG GAGGAGCCACTGCAGCTGAAGCTGGACACCCACAAAAGCCTCTACTTCAAGCCCACCTGGGTGGGCTGCTCCTCCACCAGCCCCTTCACCTTCCGCAACC CCTCGCGTCTGCCCCTGCAGTTCGAGTGGAGGGTCTCTGAGCAGCATCGAAAGCTGCTGGCTGTCCAGCCCTCCAGGGGGCTAATCCAGCCCAACGAGAG ACTTACGCTGACGTGGACCTTCAGCCCTTTGGAGGAGACCAAGTACCTGTTCCAAGTGGGGATGTGGGTCTGGGAAGCCGGCCTGTCCCCAAATGCCAAC CCCGCTGCCACCACCCACTACATGCTCCGGCTGGTGGGCGTTGGGCTCACCAGCAGCCTCTCTGCAAAGGAAAAGGAGCTGGCCTTTGGGAATGTGCTGG TGAACAGCAAGCAGTCCAGGTTCCTTGTCCTCCTGAATGACGGCAACTGCACCCTCTATTACCGCCTCTACCTGGAGCAGGGCAGCCCTGAGGCCGTTGA CAACCACCCCCTCGCTCTGCAGCTGGACCGAACAGAGGGGAGCATGCCACCCCGGTCCCAGGACACCATCTGCCTGACTGCCTGTCCCAAGCAGCGGTCC CAGTACTCCTGGACCATCACCTACTCTCTCCTTTCCCACAGAGATAACAAGGCTGGGGAGAAGCAGGAGCTGTGCTGCGTCTCCCTGGTGGCCGTGTACC CCTTGCTTTCCATCCTGGATGTCAGCTCCATGGGCAGTGCTGAGGGTATCACCCGGAAGCACCTGTGGCGCCTCTTCTCTCTGGACCTGCTTAACAGTTA CTTGGAGCGTGACCCCACCCCCTGTGAGCTCACCTACAAGGTGCCCACCCGGCACAGCATGAGCCAGATCCCCCCCGTCCTCACCCCTTTAAGGCTTGAC TTCAATTTCGGGGCCGCACCATTCAAGGCCCCACCTTCCGTGGTATTCCTGGCCCTGAAGAACAGCGGAGTGGTGTCCCTGGACTGGGCCTTCCTCCTTC CAAGTGACCAGCGGATTGACGTGGAGCTCTGGGCAGAGCAAGCAGAGTTGAATTCCACTGAGCTCCACCAGATGCGCGTGCAGGACAATTGCCTCTTCTC CATCAGCCCCAAGGCTGGGAGCCTGAGTCCTGGGCAGGAGCAGATGGTGGAGTTAAAATACAGCCACCTGTTCATCGGTACTGATCACCTCCCAGTGCTC TTCAAGGTGTCCCATGGCCGGGAGATCCTGCTAAATTTCATAGGTGTGACAGTGAAGCCGGAGCAGAAGTATGTGCACTTCACCTCTACTACCCACCAGT TCATCCCCATTCCCATTGGTGACACGCTACCCCCACGGCAGATTTATGAGCTGTATAATGGTGGCTCAGTGCCCGTGACATATGAGGTCCAGACCGATGT CCTGTCACAGGTTCAGGAAAAAAATTTTGATCACCCCATCTTTTGCTGCCTCAACCCCAAAGGGGAGATCCAGCCAGGCAGCACTGCCCGGGTCTTGTGG ATCTTCTCACCTATCGAGGCCAAGACCTACACGGTGGACGTGCCCATACACATCCTGGGATGGAACTCGGCCCTCATCCACTTCCAGGGAGTGGGCTACA ACCCCCATATGATGGGGGACACAGCCCCATTCCACAACATCTCCTCGTGGGACAACAGTTCCATACACTCTAGGCTGGTGGTGCCTGGACAGAATGTCTT CCTGTCCCAGTCTCATATTTCCCTGGGAAACATACCTGTGCAGAGCAAGTGCAGCCGCCTGCTCTTCCTCAACAACATCTCCAAGAACGAGGAAATTGCC TTCTCCTGGCAGCCAAGTCCTCTAGATTTTGGGGAGGTGTCTGTGAGTCCCATGATAGGGGTGGTGGCTCCTGAAGAGACGGTCCCATTTGTGGTGACCT TGAGGGCCTCTGTGCATGCCAGCTTCTACAGTGCAGACCTGGTATGCAAGCTGTACTCGCAGCAGCTCATGAGGCAGTATCACAAGGAGCTGCAGGAGTG GAAGGACGAGAAGGTGCGGCAGGAAGTGGAGTTCACCATCACCGACATGAAAGTGAAGAAGAGAACATGCTGCACAGCCTGTGAACCTGCGAGGAAGTAC AAGACACTGCCTCCCATCAAGAACCAGCAGTCTGTCAGCCGGCCTGCCAGCTGGAAACTGCAGACCCCAAAGGAGGAGGTGTCCTGGCCCTGCCCCCAGC CACCCTCGCCAGGCATGCTCTGCCTGGGCCTTACTGCCCGAGCCCATGCCACCGACTACTTTCTGGCTAACTTCTTCTCAGAGTTTCCCTGCCACTTTTT GCACCGGGAGCTGCCAAAGAGGAAGGCCCCCAGGGAAGAGTCAGAGACTTCTGAGGAAAAATCCCCTAACAAGTGGGGCCCTGTTTCCAAGCAGAAGAAG CAGCTCCTGGTTGACATTCTCACCACAATAATCAGGGGCCTGCTGGAAGACAAGAACTTCCATGAGGCTGTGGACCAAAGCCTGGTGGAGCAGGTGCCGT ACTTCCGCCAATTCTGGAATGAGCAGTCAACTAAGTTCATGGACCAGAAAAACAGCCTGTACTTAATGCCAATCCTGCCTGTACCCTCCAGCAGCTGGGA GGATGGGAAGGGCAAGCAGCCGAAGGAAGACAGACCAGAGCACTATCCAGGGTTGGGAAAGAAGGAAGAGGGGGAGGAGGAGAAGGGTGAAGAGGAAGAA GAAGAGTTGGAGGAGGAAGAGGAGGAAGAAGAGGAGACAGAAGAGGAGGAGTTGGGCAAGGAGGAGATAGAGGAGAAGGAGGAGGAGAGGGATGAGAAGG AAGAGAAAGTGAGCTGGGCGGGCATCGGGCCCACACCACAGCCTGAGTCCCAGGAGTCCATGCAATGGCAGTGGCAACAGCAGCTGAATGTCATGGTGAA GGAGGAGCAAGAACAGGACGAGAAGGAGGCCATCAGAAGGCTCCCGGCCTTCGCCAACCTGCAGGAGGCGCTGCTGGAGAACATGATCCAGAACATCCTG GTGGAGGCGAGCCGCGGGGAGGTGGTACTCACCTCGCGGCCACGCGTCATCGCCCTGCCGCCGTTCTGCGTGCCCAGGAGTCTGACCCCGGACACGCTGC TGCCGACGCAGCAAGCAGAGGTACTCCACCCGGTGGTGCCACTTCCTACCGACCTTCCGTAAATGCCCGCGCCCAGCCTCTCCGACATGCCGCTAGGGGT CACGCCTGGCCCCCTCTCCACCGCCAGTAAAAGCATCTAGTCTTT

refseq_CCDC108.F1 (forward primer)
refseq_CCDC108.R1 (reverse primer)
Single exon skipping

Frame 0

VLYLWRRQYGGDLTFL*FHLNVQFTIGVMFTLT GCRLVEKTQKVENPSVSFASSFPLIPLLLRGKSV QKKQAESKSQIKLHTQSAPFGLCPKDMMLTQAP SSVVRSRNSRNHTVNSGGSCLSASTVAIPAIND SSAAMSACSTISAQPASSMDTQMHSPKKQERVNK RVIWGIEVAEELHWKGWELGKETTRNLVLKNRS LKLQKMKYRPPKTKFFFTVIPQPIFLSPGITLT LPIVFRPLEAKEYMDQLWFEKAEGMFCVGLRATL PCHRLICRPPSLQLPMCAVGDTTEAFFCLDNVG DLPTFFTWEFSSPFQMLPATGLLEPGQASQIKV TFQPLTAVIYEVQATCWYGAGSRQRSSIQLQAVA KCAQLLVSIKHKCPEDQDAEGFQKLLYFGSVAV GCTSERQIRLHNPSAVNAPFRIEISPDELAEDQ AFSCPTAHGIVLPGEKKCVSVFFHPKTLDTRTVD YCSIMPSGCASKTLLKVVGFCRGPAVSLQHYCV NFSWVNLGERSEQPLWIENQSDCTAHFQFAIDC LESVFTIRPAFGTLVGKARMTLHCAFQPTHPIIC FRRVACLIHHQDPLFLDLMGTCHSDSTKPAILK PQHLTWYRTHLARGLTLYPPDILDAMLKEKKLA QDQNGALMIPIQDLEDMPAPQYPYIPPMTEFFFD GTSDITIFPPPISVEPVEVDFGACPGPEAPNPV PLCLMNHTKGKIMVVWTRRSDCPFWVTPESCDV PPLKSMAMRLHFQPPHPNCLYTVELEAFAIYKVL QSYSNIEEDCTMCPSWCLTVRARGHSYFAGFEH HIPQYSLDVPKLFPAVSSGEPTYRSLLLVNKDC KLLTFSLAPQRGSDVILRPTSGLVAPGAHQIILI CTYPEGSSWKQHTFYLQCNASPQYLKEVSMYSR EEPLQLKLDTHKSLYFKPTWVGCSSTSPFTFRN PSRLPLQFEWRVSEQHRKLLAVQPSRGLIQPNER LTLTWTFSPLEETKYLFQVGMWVWEAGLSPNAN PAATTHYMLRLVGVGLTSSLSAKEKELAFGNVL VNSKQSRFLVLLNDGNCTLYYRLYLEQGSPEAVD NHPLALQLDRTEGSMPPRSQDTICLTACPKQRS QYSWTITYSLLSHRDNKAGEKQELCCVSLVAVY PLLSILDVSSMGSAEGITRKHLWRLFSLDLLNSY LERDPTPCELTYKVPTRHSMSQIPPVLTPLRLD FNFGAAPFKAPPSVVFLALKNSGVVSLDWAFLL PSDQRIDVELWAEQAELNSTELHQMRVQDNCLFS ISPKAGSLSPGQEQMVELKYSHLFIGTDHLPVL FKVSHGREILLNFIGVTVKPEQKYVHFTSTTHQ FIPIPIGDTLPPRQIYELYNGGSVPVTYEVQTDV LSQVQEKNFDHPIFCCLNPKGEIQPGSTARVLW IFSPIEAKTYTVDVPIHILGWNSALIHFQGVGY NPHMMGDTAPFHNISSWDNSSIHSRLVVPGQNVF LSQSHISLGNIPVQSKCSRLLFLNNISKNEEIA FSWQPSPLDFGEVSVSPMIGVVAPEETVPFVVT LRASVHASFYSADLVCKLYSQQLMRQYHKELQEW KDEKVRQEVEFTITDMKVKKRTCCTACEPARKY KTLPPIKNQQSVSRPASWKLQTPKEEVSWPCPQ PPSPGMLCLGLTARAHATDYFLANFFSEFPCHFL HRELPKRKAPREESETSEEKSPNKWGPVSKQKK QLLVDILTTIIRGLLEDKNFHEAVDQSLVEQVP YFRQFWNEQSTKFMDQKNSLYLMPILPVPSSSWE DGKGKQPKEDRPEHYPGLGKKEEGEEEKGEEEE EELEEEEEEEEETEEEELGKEEIEEKEEERDEK EEKVSWAGIGPTPQPESQESMQWQWQQQLNVMVK EEQEQDEKEAIRRLPAFANLQEALLENMIQNIL VEASRGEVVLTSRPRVIALPPFCVPRSLTPDTL LPTQQAEVLHPVVPLPTDLP*MPAPSLSDMPLGV TPGPLSTASKSI*S

Frame 1

SCIYGDGNMEAILHFFDFI*TSSSQLE*CLP*P VVDWWRKPRRWRIHQSHLPLLSPLFLFS*EARV FRRNKQRVKAR*SSILRVLPLDCVPRT*CSPRLQ APS*GPGTAGTTP*TLVDPA*VPAQWPSLPSTT AVQP*VPAAPSAPSPQAPWTLRCTPQRSRRE*T RGSSGALRWLRSCIGKAGS*ERRPQGIWF*KIDP *NSRR*STGPPRPSSSSRSSLSPSS*AQA*PSR SPSSSGLWRRRSTWTSCGLRKRRGCSVSAYGPP CPATG*SAAHHPCSCPCVLWEIRLRPFSAWIMWG TCPPSSPGSSPAHSRCCPPRGSWSQARPLRSR* PFSPLQPSSTRCRPRAGTGRAAGRGAASSCRLW PSAPSCW*A*STSARRTRMPRASRSCCTLALLLW AAPRRGRSGYTTRRR*MPPSGLKFPRMNWPKTR PSHAPRPMASCFRERRNVCRCSSTPRLWTPELW TTAPSCLLAVPPRPCLKSLVSVEALLCPCSTTVS TSAGSTLGSAPSSPCGLRTNRTARPTSSLPSTA WRVSLPSGLPLGRWWARPV*PCTVPSSPLTPSS AFGVWPVSSTTRTHCSWT*WGPATRTAPSQPS*S LSTSPGTAHTWPGA*RSTPLTSWMPC*RRRSWH RTRTGLS*FPSRIWRTCRPRSTLISPP*PSSSS TAPAT*PSSPRPSV*SLSR*TSVPAQGLRPPTLY PCA**TTPRARSWWSGREGLTAPSG*LQRAATC PHSSPWPCACTSSRLTPTAFTRWSSKPSPSIRS CRATVILRRTAPCAHPGA*RCGHEATAISLALST TSPSIP*MSPSYFQQCPPVSPPTAACSWSTKTA SC*PSAWPPREAQTSSFGPLRALWHPGPTRSSS SAPTLRAAPGSSTLSICSAMLPPSISRR*ACTAG RSHCS*SWTPTKASTSSPPGWAAPPPAPSPSAT PRVCPCSSSGGSLSSIESCWLSSPPGG*SSPTR DLR*RGPSALWRRPSTCSKWGCGSGKPACPQMPT PLPPPTTCSGWWALGSPAASLQRKRSWPLGMCW *TASSPGSLSS*MTATAPSITASTWSRAALRPL TTTPSLCSWTEQRGACHPGPRTPSA*LPVPSSGP STPGPSPTLSFPTEITRLGRSRSCAASPWWPCT PCFPSWMSAPWAVLRVSPGSTCGASSLWTCLTV TWSVTPPPVSSPTRCPPGTA*ARSPPSSPL*GLT SISGPHHSRPHLPWYSWP*RTAEWCPWTGPSSF QVTSGLTWSSGQSKQS*IPLSSTRCACRTIASS PSAPRLGA*VLGRSRWWS*NTATCSSVLITSQCS SRCPMAGRSC*IS*V*Q*SRSRSMCTSPLLPTS SSPFPLVTRYPHGRFMSCIMVAQCP*HMRSRPM SCHRFRKKILITPSFAASTPKGRSSQAALPGSCG SSHLSRPRPTRWTCPYTSWDGTRPSSTSREWAT TPI*WGTQPHSTTSPRGTTVPYTLGWWCLDRMS SCPSLIFPWETYLCRASAAACSSSTTSPRTRKLP SPGSQVL*ILGRCL*VP**GWWLLKRRSHLW*P *GPLCMPASTVQTWYASCTRSSS*GSITRSCRS GRTRRCGRKWSSPSPT*K*RREHAAQPVNLRGST RHCLPSRTSSLSAGLPAGNCRPQRRRCPGPAPS HPRQACSAWALLPEPMPPTTFWLTSSQSFPATF CTGSCQRGRPPGKSQRLLRKNPLTSGALFPSRRS SSWLTFSPQ*SGACWKTRTSMRLWTKAWWSRCR TSANSGMSSQLSSWTRKTACT*CQSCLYPPAAG RMGRASSRRKTDQSTIQGWERRKRGRRRRVKRKK KSWRRKRRKKRRQKRRSWARRR*RRRRRRGMRR KRK*AGRASGPHHSLSPRSPCNGSGNSS*MSW* RRSKNRTRRRPSEGSRPSPTCRRRCWRT*SRTSW WRRAAGRWYSPRGHASSPCRRSACPGV*PRTRC CRRSKQRYSTRWCHFLPTFRKCPRPASPTCR*G SRLAPSPPPVKASSL

Frame 2

PVSMETAIWRRSYISLISSERPVHNWSDVYLNR L*TGGENPEGGESISLICLFFPPYSSSPKRQEC SEETSRE*KPDKAPYSECSLWTVSQGHDAHPGS KLRREVQEQQEPHRELWWILPECQHSGHPCHQRQ QCSHECLQHHQRPARKLHGHSDALPKEAGESEQ EGHLGH*GG*GAALERLGARKGDHKESGSEKSI LETPEDEVQAPQDQVLLHGHPSAHLPEPRHNPHA PHRLPASGGEGVHGPAVV*ESGGDVLCRPTGHP ALPQADLPPTIPAAAHVCCGRYD*GLFLPG*CG GPAHLLHLGVLQPIPDAARHGAPGARPGLSDQGD LSAPYSRHLRGAGHVLVRGGQPAEEQHPAAGCG QVRPAAGEHKAQVPGGPGCRGLPEAVVLWLCCC GLHLGEADQATQPVGGKCPLQD*NFPG*TGRRPG LLMPHGPWHRASGREEMCVGVLPPQDSGHQNCG LLLHHAFWLCLQDPA*SRWFL*RPCCVPAALLC QLQLGQPWGALRAAPVD*EPIGLHGPLPVCHRLL GECLYHQACLWDAGGQGPYDPALCLPAHSPHHL LSACGLSHPPPGPTVPGPDGDLPLGQHQASHPE ASAPHLVPHTPGPGPDALPP*HPGCHAEGEEAGT GPERGSHDSHPGSGGHAGPAVPLYPPHDRVLLR RHQRHNHLPPAHQCRACRGRLRCLPRA*GPQPC TPVPDEPHQGQDHGGLDAKV*LPLLGDSRELRRA PTQVHGHAPALPAASPQLPLHGGARSLRHL*GP AELQ*Y*GGLHHVPILVPDGAGTRPQLFRWL*A PHPPVFPRCPQAISSSVLR*AHLPQPAPGQQRLQ AADLQPGPPERLRRHPSAHFGPCGTRGPPDHPH LHLP*GQLLEAAHFLSAVQCFPPVSQGGEHVQP GGATAAEAGHPQKPLLQAHLGGLLLHQPLHLPQP LASAPAVRVEGL*AASKAAGCPALQGANPAQRE TYADVDLQPFGGDQVPVPSGDVGLGSRPVPKCQ PRCHHPLHAPAGGRWAHQQPLCKGKGAGLWECAG EQQAVQVPCPPE*RQLHPLLPPLPGAGQP*GR* QPPPRSAAGPNRGEHATPVPGHHLPDCLSQAAV PVLLDHHLLSPFPQR*QGWGEAGAVLRLPGGRVP LAFHPGCQLHGQC*GYHPEAPVAPLLSGPA*QL LGA*PHPL*AHLQGAHPAQHEPDPPRPHPFKA* LQFRGRTIQGPTFRGIPGPEEQRSGVPGLGLPPS K*PAD*RGALGRASRVEFH*APPDARAGQLPLL HQPQGWEPESWAGADGGVKIQPPVHRY*SPPSA LQGVPWPGDPAKFHRCDSEAGAEVCALHLYYPPV HPHSHW*HATPTADL*AV*WWLSARDI*GPDRC PVTGSGKKF*SPHLLLPQPQRGDPARQHCPGLV DLLTYRGQDLHGGRAHTHPGMELGPHPLPGSGLQ PPYDGGHSPIPQHLLVGQQFHTL*AGGAWTECL PVPVSYFPGKHTCAEQVQPPALPQQHLQERGNC LLLAAKSSRFWGGVCESHDRGGGS*RDGPICGDL EGLCACQLLQCRPGMQAVLAAAHEAVSQGAAGV EGREGAAGSGVHHHRHESEEENMLHSL*TCEEV QDTASHQEPAVCQPACQLETADPKGGGVLALPPA TLARHALPGPYCPSPCHRLLSG*LLLRVSLPLF APGAAKEEGPQGRVRDF*GKIP*QVGPCFQAEE AAPG*HSHHNNQGPAGRQELP*GCGPKPGGAGAV LPPILE*AVN*VHGPEKQPVLNANPACTLQQLG GWEGQAAEGRQTRALSRVGKEGRGGGGEG*RGR RRVGGGRGGRRGDRRGGVGQGGDRGEGGGEG*EG RESELGGHRAHTTA*VPGVHAMAVATAAECHGE GGARTGREGGHQKAPGLRQPAGGAAGEHDPEHP GGGEPRGGGTHLAATRHRPAAVLRAQESDPGHAA ADAASRGTPPGGATSYRPSVNARAQPLRHAARG HAWPPLHRQ*KHLVF