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Sequences

Sequence NM_173060

CACTCAGAGAGCTGGGCTGGAGCTCCAAGCGGAAACCGCGGGAGCCGAGCCCAGCTAGGAATGCAGACCTCCTGAAAACCAAGCCGAGGACTGCGGGGTC
CGGTGTCCACGCAGAGTGTCAGCTTCCTCTGGTGCAACCAGCAAGTCTTCCAGTATGAATCCCACAGAAACCAAGGCTGTAAAAACAGAACCTGAGAAGA
AGTCACAGTCAACCAAGCTGTCTGTGGTTCATGAGAAAAAATCCCAAGAAGGAAAGCCAAAAGAACACACAGAGCCAAAAAGCCTACCCAAGCAGGCATC
AGATACAGGAAGTAACGATGCTCACAATAAAAAAGCAGTTTCCAGATCAGCTGAACAGCAGCCATCAGAGAAATCAACAGAACCAAAGACTAAACCACAA
GACATGATTTCTGCTGGTGGAGAGAGTGTTGCTGGTATCACTGCAATATCTGGCAAGCCGGGTGACAAGAAAAAAGAAAAGAAATCATTAACCCCAGCTG
TGCCAGTTGAATCTAAACCGGATAAACCATCGGGAAAGTCAGGCATGGATGCTGCTTTGGATGACTTAATAGATACTTTAGGAGGACCTGAAGAAACTGA
AGAAGAAAATACAACGTATACTGGACCAGAAGTTTCAGATCCAATGAGTTCCACCTACATAGAGGAATTGGGTAAAAGAGAAGTCACAATTCCTCCAAAA
TATAGGGAACTATTGGCTAAAAAGGAAGGGATCACAGGGCCTCCTGCAGACTCTTCGAAACCCATAGGGCCAGATGATGCTATAGACGCCTTGTCATCTG
ACTTCACCTGTGGGTCGCCTACAGCTGCTGGAAAGAAAACTGAAAAAGAGGAATCTACAGAAGTTTTAAAAGCTCAGTCAGCAGGGACAGTCAGAAGTGC
TGCTCCACCCCAAGAGAAGAAAAGAAAGGTGGAGAAGGATACAATGAGTGATCAAGCACTCGAGGCTCTGTCGGCTTCACTGGGCACCCGGCAAGCAGAA
CCTGAGCTCGACCTCCGCTCAATTAAGGAAGTCGATGAGGCAAAAGCTAAAGAAGAAAAACTAGAGAAGTGTGGTGAGGATGATGAAACAATCCCATCTG
AGTACAGATTAAAACCAGCCACGGATAAAGATGGAAAACCACTATTGCCAGAGCCTGAAGAAAAACCCAAGCCTCGGAGTGAATCAGAACTCATTGATGA
ACTTTCAGAAGATTTTGACCGGTCTGAATGTAAAGAGAAACCATCTAAGCCAACTGAAAAGACAGAAGAATCTAAGGCCGCTGCTCCAGCTCCTGTGTCG
GAGGCTGTGTGTCGGACCTCCATGTGTAGTATACAGTCAGCACCCCCTGAGCCGGCTACCTTGAAGGGCACAGTGCCAGATGATGCTGTAGAAGCCTTGG
CTGATAGCCTGGGGAAAAAGGAAGCAGATCCAGAAGATGGAAAACCTGTGATGGATAAAGTCAAGGAGAAGGCCAAAGAAGAAGACCGTGAAAAGCTTGG
TGAAAAAGAAGAAACAATTCCTCCTGATTATAGATTAGAAGAGGTCAAGGATAAAGATGGAAAGCCACTCCTGCCAAAAGAGTCTAAGGAACAGCTTCCA
CCCATGAGTGAAGACTTCCTTCTGGATGCTTTGTCTGAGGACTTCTCTGGTCCACAAAATGCTTCATCTCTTAAATTTGAAGATGCTAAACTTGCTGCTG
CCATCTCTGAAGTGGTTTCCCAAACCCCAGCTTCAACGACCCAAGCTGGAGCCCCACCCCGTGATACCTCGCAGAGTGACAAAGACCTCGATGATGCCTT
GGATAAACTCTCTGACAGTCTAGGACAAAGGCAGCCTGACCCAGATGAGAACAAACCAATGGAAGATAAAGTAAAGGAAAAAGCTAAAGCTGAACATAGA
GACAAGCTTGGAGAAAGAGATGACACTATCCCACCTGAATACAGACATCTCCTGGATGATAATGGACAGGACAAACCAGTGAAGCCACCTACAAAGAAAT
CAGAGGATTCAAAGAAACCTGCAGATGACCAAGACCCCATTGATGCTCTCTCAGGAGATCTGGACAGCTGTCCCTCCACTACAGAAACCTCACAGAACAC
AGCAAAGGATAAGTGCAAGAAGGCTGCTTCCAGCTCCAAAGCACCTAAGAATGGAGGTAAAGCGAAGGATTCAGCAAAGACAACAGAGGAAACTTCCAAG
CCAAAAGATGACTAAAGAAATACAAGTTAAGGTATCTGGTATCTGCATGTAAAATCTTCAGCTGGTGGATGGTGACTTTTGAAGAACAAAAGGCTTTGGC
AACAGAAAACAATTGTTCTGGGTGATTTCTAGAATGGTTTTTGTTGAGTCTCTGAACATCCTAAATATTGGTTTGTTATTCTTTTCCAGAAAGAAAATGA
ATTTGACTGGTTCACCTGTGTACTGAGTATTGATAAACTTTGAATTTTTTTAATTGCCTTCAATTGGGAGAGAAAGCTTTATATTTGTAAGAAATATATT
TGATAAAGTTTCTTAAAGCAACACCAAAAAAACAAAAGAAAAGCTAAGTGAATTTTTGCACATTCTACACACAGTGCCTGTAAATCTCATTTGTATTTTC
AGTTTGCCCTTAATTTTTTTTGTTAGTGTTTAGAAAACAATGTTTTAAACATTCTTCAGTGTTCTGATTTCTTATTACCCCCTTTCCTCTTGGGCTTTTG
AACTGTATTTGATGTTGCTTTGGGATAATGTTTATAAGTCAAACATAAGATATTGTACATTGGGCACATATCTCCTCTTGGGCTGCTAATAATAAATTAA
TAACAGGTAACCTGGACAAACCAGGAAGCACCAAACCCCTTTTCAGTTTGAACTCTTCTTTGCCAGGTGTGAGGACTTCTGCATCTTACAGTCAGCACAG
AACACACTGAGACTTGAATCAAGTCAGCAACAGAGCAAAATAAAGGTTAGATAAGTCCTTGTGTAGCAAATTTCGAGCATAAGAAATAAAATCTAATTAA
TTCTTAGGGTACTCATCTGACTTGAACTCTGTTGGTTTACTGTGTTAGTAAACTGTGCTTTCTATTATCTATACATAAAACCTGAGCAGCAACTGTGTCT
TTAGAGCTATTGCCACATTAGCCTTTGCACTGTATAGCGTCTGGCTTTATGGAACTTAAGTTTACCAAATATAAAAAGAAACTTCTGCTTTTAAAAAAAT
TATATATATATATTAAATTTGAAACCTGCATTTCTCCCACAGCAATGTAAGAAGTAGGCTCTGATGTCCTACCACTTTGAATGGTTTTCTAATATCTTAA
TGAATAGTTCCTGAACATTGCACTGATATCATCGATTAGAATTTTGATATTTAATTTCATCTTTATTTCCTGGTAGAGAATGCAGGAAAAGATGTCAGGT
ACATAACATAAAACAGATTGGGAATTTATTGTTTCCAAAGGGCATGGCCTTCCTTAGCATCAGTTTGAAGCTTTTGTTATGACTTAGCTGACTTGTGGCA
GCGGGGCAAGCAAAAACAATAACACTGCTTATAAATGGCACCACATCTTGTTAACCTCCCCCCCAAATACTCTCTGAAAGTCATGCACATACCTATGGGA
TTTTACACACCACCAGCTTAAAATGCTATGTCTCTATCCATCAGAAATAGTCATTATTCTATTTTTAAGGCAGCAACAAGAAAAGAAAAAACACTTTTCC
TGAGGGATTTCTAACCATGTATCTAATCCTCCCATTTGGGCAGTATAGGTGTTTGCTTTTTTGTTTTCTTTTTTTAAGAAAAACCTTGAAACCTTTGACA
CTGACAGATGTGTTTGCAAGGATACGGCTTCAGTATTACTAATTTCCATGTGTATCTGGAAGTATTTTTAAATGGCATACCAAAATCCAGAAGTTTAAAG
ATGCCTATAAAAGTAAACAACATTTATTTAAAAAGAACTCTGAATATGCCTTCTTTTTTAATTAGAAATATCTTCGAGACTTGGGTGTTTGTTAATAACT
AATAACTGGAGTAAGCTACAGGATCTAAAGCAGCCCTTTTTACAGTCTAGTTAGGAGAGAGAAAATAATTGCAAATATCCACTTAGAGGCAAAGAACAAT
TTTTTATTATCAAAAAGGTTTCTGCACATTGTTGTGGCAATATTGTATCTGTTTAGAAAATGGGCTTTTCCAAAAGCAAACAAAGATAGGTTCCTCAGGT
GACCAAAACTGAAAATCAATATTTCCATGTTTCATTAATCAAGGCATAAAATACAATTAAAGCAAAATATTTTACATTAAAA
  • refseq_CAST.F2 (forward primer)
  • refseq_CAST.R2 (reverse primer)
  • Exon skipping and alternative donor or acceptor

Frame 0

HSESWAGAPSGNRGSRAQLGMQTS*KPSRGLRG
PVSTQSVSFLWCNQQVFQYESHRNQGCKNRT*EE
VTVNQAVCGS*EKIPRRKAKRTHRAKKPTQAGI
RYRK*RCSQ*KSSFQIS*TAAIREINRTKD*TT
RHDFCWWRECCWYHCNIWQAG*QEKRKEIINPSC
AS*I*TG*TIGKVRHGCCFG*LNRYFRRT*RN*
RRKYNVYWTRSFRSNEFHLHRGIG*KRSHNSSK
I*GTIG*KGRDHRASCRLFETHRAR*CYRRLVI*
LHLWVAYSCWKEN*KRGIYRSFKSSVSRDSQKC
CSTPREEKKGGEGYNE*SSTRGSVGFTGHPASR
T*ARPPLN*GSR*GKS*RRKTREVW*G**NNPI*
VQIKTSHG*RWKTTIARA*RKTQASE*IRTH**
TFRRF*PV*M*RETI*AN*KDRRI*GRCSSSCV
GGCVSDLHV*YTVSTP*AGYLEGHSAR*CCRSLG
**PGEKGSRSRRWKTCDG*SQGEGQRRRP*KAW
*KRRNNSS*L*IRRGQG*RWKATPAKRV*GTAS
THE*RLPSGCFV*GLLWSTKCFIS*I*RC*TCCC
HL*SGFPNPSFNDPSWSPTP*YLAE*QRPR*CL
G*TL*QSRTKAA*PR*EQTNGR*SKGKS*S*T*
RQAWRKR*HYPT*IQTSPG**WTGQTSEATYKEI
RGFKETCR*PRPH*CSLRRSGQLSLHYRNLTEH
SKG*VQEGCFQLQST*EWR*SEGFSKDNRGNFQ
AKR*LKKYKLRYLVSACKIFSWWMVTFEEQKALA
TENNCSG*FLEWFLLSL*TS*ILVCYSFPERK*
I*LVHLCTEY**TLNFFNCLQLGEKALYL*EIY
LIKFLKATPKKQKKS*VNFCTFYTQCL*ISFVFS
VCP*FFLLVFRKQCFKHSSVF*FLITPFPLGLL
NCI*CCFGIMFISQT*DIVHWAHISSWAANNKL
ITGNLDKPGSTKPLFSLNSSLPGVRTSASYSQHR
TH*DLNQVSNRAK*RLDKSLCSKFRA*EIKSN*
FLGYSSDLNSVGLLC**TVLSIIYT*NLSSNCV
FRAIATLAFALYSVWLYGT*VYQI*KETSAFKKI
IYIY*I*NLHFSHSNVRSRL*CPTTLNGFLIS*
*IVPEHCTDIID*NFDI*FHLYFLVENAGKDVR
YIT*NRLGIYCFQRAWPSLASV*SFCYDLADLWQ
RGKQKQ*HCL*MAPHLVNLPPKYSLKVMHIPMG
FYTPPA*NAMSLSIRNSHYSIFKAATRKEKTLF
LRDF*PCI*SSHLGSIGVCFFVFFF*EKP*NL*H
*QMCLQGYGFSITNFHVYLEVFLNGIPKSRSLK
MPIKVNNIYLKRTLNMPSFLIRNIFETWVFVNN
**LE*ATGSKAALFTV*LGERK*LQIST*RQRTI
FYYQKGFCTLLWQYCICLENGLFQKQTKIGSSG
DQN*KSIFPCFINQGIKYN*SKIFYIK

Frame 1

TQRAGLELQAETAGAEPS*ECRPPENQAEDCGV
RCPRRVSASSGATSKSSSMNPTETKAVKTEPEK
KSQSTKLSVVHEKKSQEGKPKEHTEPKSLPKQAS
DTGSNDAHNKKAVSRSAEQQPSEKSTEPKTKPQ
DMISAGGESVAGITAISGKPGDKKKEKKSLTPA
VPVESKPDKPSGKSGMDAALDDLIDTLGGPEETE
EENTTYTGPEVSDPMSSTYIEELGKREVTIPPK
YRELLAKKEGITGPPADSSKPIGPDDAIDALSS
DFTCGSPTAAGKKTEKEESTEVLKAQSAGTVRSA
APPQEKKRKVEKDTMSDQALEALSASLGTRQAE
PELDLRSIKEVDEAKAKEEKLEKCGEDDETIPS
EYRLKPATDKDGKPLLPEPEEKPKPRSESELIDE
LSEDFDRSECKEKPSKPTEKTEESKAAAPAPVS
EAVCRTSMCSIQSAPPEPATLKGTVPDDAVEAL
ADSLGKKEADPEDGKPVMDKVKEKAKEEDREKLG
EKEETIPPDYRLEEVKDKDGKPLLPKESKEQLP
PMSEDFLLDALSEDFSGPQNASSLKFEDAKLAA
AISEVVSQTPASTTQAGAPPRDTSQSDKDLDDAL
DKLSDSLGQRQPDPDENKPMEDKVKEKAKAEHR
DKLGERDDTIPPEYRHLLDDNGQDKPVKPPTKK
SEDSKKPADDQDPIDALSGDLDSCPSTTETSQNT
AKDKCKKAASSSKAPKNGGKAKDSAKTTEETSK
PKDD*RNTS*GIWYLHVKSSAGGW*LLKNKRLW
QQKTIVLGDF*NGFC*VSEHPKYWFVILFQKENE
FDWFTCVLSIDKL*IFLIAFNWERKLYICKKYI
**SFLKQHQKNKRKAK*IFAHSTHSACKSHLYF
QFALNFFC*CLENNVLNILQCSDFLLPPFLLGF*
TVFDVALG*CL*VKHKILYIGHISPLGLLIIN*
*QVTWTNQEAPNPFSV*TLLCQV*GLLHLTVST
EHTET*IKSATEQNKG*ISPCVANFEHKK*NLIN
S*GTHLT*TLLVYCVSKLCFLLSIHKT*AATVS
LELLPH*PLHCIASGFMELKFTKYKKKLLLLKK
LYIYIKFETCISPTAM*EVGSDVLPL*MVF*YLN
E*FLNIALISSIRILIFNFIFISW*RMQEKMSG
T*HKTDWEFIVSKGHGLP*HQFEAFVMT*LTCG
SGASKNNNTAYKWHHILLTSPPNTL*KSCTYLWD
FTHHQLKMLCLYPSEIVIILFLRQQQEKKKHFS
*GISNHVSNPPIWAV*VFAFLFSFFKKNLETFD
TDRCVCKDTASVLLISMCIWKYF*MAYQNPEV*R
CL*K*TTFI*KEL*ICLLF*LEISSRLGCLLIT
NNWSKLQDLKQPFLQSS*ERENNCKYPLRGKEQ
FFIIKKVSAHCCGNIVSV*KMGFSKSKQR*VPQV
TKTENQYFHVSLIKA*NTIKAKYFTLK

Frame 2

LRELGWSSKRKPREPSPARNADLLKTKPRTAGS
GVHAECQLPLVQPASLPV*IPQKPRL*KQNLRR
SHSQPSCLWFMRKNPKKESQKNTQSQKAYPSRH
QIQEVTMLTIKKQFPDQLNSSHQRNQQNQRLNHK
T*FLLVERVLLVSLQYLASRVTRKKKRNH*PQL
CQLNLNRINHRESQAWMLLWMT**IL*EDLKKL
KKKIQRILDQKFQIQ*VPPT*RNWVKEKSQFLQN
IGNYWLKRKGSQGLLQTLRNP*GQMML*TPCHL
TSPVGRLQLLERKLKKRNLQKF*KLSQQGQSEV
LLHPKRRKERWRRIQ*VIKHSRLCRLHWAPGKQN
LSSTSAQLRKSMRQKLKKKN*RSVVRMMKQSHL
STD*NQPRIKMENHYCQSLKKNPSLGVNQNSLM
NFQKILTGLNVKRNHLSQLKRQKNLRPLLQLLCR
RLCVGPPCVVYSQHPLSRLP*RAQCQMML*KPW
LIAWGKRKQIQKMENL*WIKSRRRPKKKTVKSL
VKKKKQFLLIID*KRSRIKMESHSCQKSLRNSFH
P*VKTSFWMLCLRTSLVHKMLHLLNLKMLNLLL
PSLKWFPKPQLQRPKLEPHPVIPRRVTKTSMMP
WINSLTV*DKGSLTQMRTNQWKIK*RKKLKLNIE
TSLEKEMTLSHLNTDISWMIMDRTNQ*SHLQRN
QRIQRNLQMTKTPLMLSQEIWTAVPPLQKPHRT
QQRISARRLLPAPKHLRMEVKRRIQQRQQRKLPS
QKMTKEIQVKVSGICM*NLQLVDGDF*RTKGFG
NRKQLFWVISRMVFVESLNILNIGLLFFSRKKM
NLTGSPVY*VLINFEFF*LPSIGRESFIFVRNIF
DKVS*SNTKKTKEKLSEFLHILHTVPVNLICIF
SLPLIFFVSV*KTMF*TFFSVLISYYPLSSWAF
ELYLMLLWDNVYKSNIRYCTLGTYLLLGC***IN
NR*PGQTRKHQTPFQFELFFARCEDFCILQSAQ
NTLRLESSQQQSKIKVR*VLV*QISSIRNKI*L
ILRVLI*LELCWFTVLVNCAFYYLYIKPEQQLCL
*SYCHISLCTV*RLALWNLSLPNIKRNFCF*KN
YIYILNLKPAFLPQQCKK*ALMSYHFEWFSNIL
MNSS*TLH*YHRLEF*YLISSLFPGRECRKRCQV
HNIKQIGNLLFPKGMAFLSISLKLLL*LS*LVA
AGQAKTITLLINGTTSC*PPPQILSESHAHTYG
ILHTTSLKCYVSIHQK*SLFYF*GSNKKRKNTFP
EGFLTMYLILPFGQYRCLLFCFLFLRKTLKPLT
LTDVFARIRLQYY*FPCVSGSIFKWHTKIQKFK
DAYKSKQHLFKKNSEYAFFFN*KYLRDLGVC**L
ITGVSYRI*SSPFYSLVRREKIIANIHLEAKNN
FLLSKRFLHIVVAILYLFRKWAFPKANKDRFLR
*PKLKINISMFH*SRHKIQLKQNILH*

Sequence NM_001750

AGAAAAAAGCAGCAAGCCTCGGCAGCAGTCAATCCTCCAGAACCTATGCTGGTGGAACAGCCTCGGCCACCAAGGTGTCAGCTTCCTCTGGTGCAACCAG
CAAGTCTTCCAGTATGAATCCCACAGAAACCAAGGCCATTCCAGTCAGCCAACAGATGGAAGGACCACATCTTCCTAACAAGAAAAAACACAAAAAACAG
GCTGTAAAAACAGAACCTGAGAAGAAGTCACAGTCAACCAAGCTGTCTGTGGTTCATGAGAAAAAATCCCAAGAAGGAAAGCCAAAAGAACACACAGAGC
CAAAAAGCCTACCCAAGCAGGCATCAGATACAGGAAGTAACGATGCTCACAATAAAAAAGCAGTTTCCAGATCAGCTGAACAGCAGCCATCAGAGAAATC
AACAGAACCAAAGACTAAACCACAAGACATGATTTCTGCTGGTGGAGAGAGTGTTGCTGGTATCACTGCAATATCTGGCAAGCCGGGTGACAAGAAAAAA
GAAAAGAAATCATTAACCCCAGCTGTGCCAGTTGAATCTAAACCGGATAAACCATCGGGAAAGTCAGGCATGGATGCTGCTTTGGATGACTTAATAGATA
CTTTAGGAGGACCTGAAGAAACTGAAGAAGAAAATACAACGTATACTGGACCAGAAGTTTCAGATCCAATGAGTTCCACCTACATAGAGGAATTGGGTAA
AAGAGAAGTCACAATTCCTCCAAAATATAGGGAACTATTGGCTAAAAAGGAAGGGATCACAGGGCCTCCTGCAGACTCTTCGAAACCCATAGGGCCAGAT
GATGCTATAGACGCCTTGTCATCTGACTTCACCTGTGGGTCGCCTACAGCTGCTGGAAAGAAAACTGAAAAAGAGGAATCTACAGAAGTTTTAAAAGCTC
AGTCAGCAGGGACAGTCAGAAGTGCTGCTCCACCCCAAGAGAAGAAAAGAAAGGTGGAGAAGGATACAATGAGTGATCAAGCACTCGAGGCTCTGTCGGC
TTCACTGGGCACCCGGCAAGCAGAACCTGAGCTCGACCTCCGCTCAATTAAGGAAGTCGATGAGGCAAAAGCTAAAGAAGAAAAACTAGAGAAGTGTGGT
GAGGATGATGAAACAATCCCATCTGAGTACAGATTAAAACCAGCCACGGATAAAGATGGAAAACCACTATTGCCAGAGCCTGAAGAAAAACCCAAGCCTC
GGAGTGAATCAGAACTCATTGATGAACTTTCAGAAGATTTTGACCGGTCTGAATGTAAAGAGAAACCATCTAAGCCAACTGAAAAGACAGAAGAATCTAA
GGCCGCTGCTCCAGCTCCTGTGTCGGAGGCTGTGTGTCGGACCTCCATGTGTAGTATACAGTCAGCACCCCCTGAGCCGGCTACCTTGAAGGGCACAGTG
CCAGATGATGCTGTAGAAGCCTTGGCTGATAGCCTGGGGAAAAAGGAAGCAGATCCAGAAGATGGAAAACCTGTGATGGATAAAGTCAAGGAGAAGGCCA
AAGAAGAAGACCGTGAAAAGCTTGGTGAAAAAGAAGAAACAATTCCTCCTGATTATAGATTAGAAGAGGTCAAGGATAAAGATGGAAAGCCACTCCTGCC
AAAAGAGTCTAAGGAACAGCTTCCACCCATGAGTGAAGACTTCCTTCTGGATGCTTTGTCTGAGGACTTCTCTGGTCCACAAAATGCTTCATCTCTTAAA
TTTGAAGATGCTAAACTTGCTGCTGCCATCTCTGAAGTGGTTTCCCAAACCCCAGCTTCAACGACCCAAGCTGGAGCCCCACCCCGTGATACCTCGCAGA
GTGACAAAGACCTCGATGATGCCTTGGATAAACTCTCTGACAGTCTAGGACAAAGGCAGCCTGACCCAGATGAGAACAAACCAATGGAAGATAAAGTAAA
GGAAAAAGCTAAAGCTGAACATAGAGACAAGCTTGGAGAAAGAGATGACACTATCCCACCTGAATACAGACATCTCCTGGATGATAATGGACAGGACAAA
CCAGTGAAGCCACCTACAAAGAAATCAGAGGATTCAAAGAAACCTGCAGATGACCAAGACCCCATTGATGCTCTCTCAGGAGATCTGGACAGCTGTCCCT
CCACTACAGAAACCTCACAGAACACAGCAAAGGATAAGTGCAAGAAGGCTGCTTCCAGCTCCAAAGCACCTAAGAATGGAGGTAAAGCGAAGGATTCAGC
AAAGACAACAGAGGAAACTTCCAAGCCAAAAGATGACTAAAGAAATACAAGTTAAGGTATCTGGTATCTGCATGTAAAATCTTCAGCTGGTGGATGGTGA
CTTTTGAAGAACAAAAGGCTTTGGCAACAGAAAACAATTGTTCTGGGTGATTTCTAGAATGGTTTTTGTTGAGTCTCTGAACATCCTAAATATTGGTTTG
TTATTCTTTTCCAGAAAGAAAATGAATTTGACTGGTTCACCTGTGTACTGAGTATTGATAAACTTTGAATTTTTTTAATTGCCTTCAATTGGGAGAGAAA
GCTTTATATTTGTAAGAAATATATTTGATAAAGTTTCTTAAAGCAACACCAAAAAAACAAAAGAAAAGCTAAGTGAATTTTTGCACATTCTACACACAGT
GCCTGTAAATCTCATTTGTATTTTCAGTTTGCCCTTAATTTTTTTTGTTAGTGTTTAGAAAACAATGTTTTAAACATTCTTCAGTGTTCTGATTTCTTAT
TACCCCCTTTCCTCTTGGGCTTTTGAACTGTATTTGATGTTGCTTTGGGATAATGTTTATAAGTCAAACATAAGATATTGTACATTGGGCACATATCTCC
TCTTGGGCTGCTAATAATAAATTAATAACAGGTAACCTGGACAAACCAGGAAGCACCAAACCCCTTTTCAGTTTGAACTCTTCTTTGCCAGGTGTGAGGA
CTTCTGCATCTTACAGTCAGCACAGAACACACTGAGACTTGAATCAAGTCAGCAACAGAGCAAAATAAAGGTTAGATAAGTCCTTGTGTAGCAAATTTCG
AGCATAAGAAATAAAATCTAATTAATTCTTAGGGTACTCATCTGACTTGAACTCTGTTGGTTTACTGTGTTAGTAAACTGTGCTTTCTATTATCTATACA
TAAAACCTGAGCAGCAACTGTGTCTTTAGAGCTATTGCCACATTAGCCTTTGCACTGTATAGCGTCTGGCTTTATGGAACTTAAGTTTACCAAATATAAA
AAGAAACTTCTGCTTTTAAAAAAATTATATATATATATTAAATTTGAAACCTGCATTTCTCCCACAGCAATGTAAGAAGTAGGCTCTGATGTCCTACCAC
TTTGAATGGTTTTCTAATATCTTAATGAATAGTTCCTGAACATTGCACTGATATCATCGATTAGAATTTTGATATTTAATTTCATCTTTATTTCCTGGTA
GAGAATGCAGGAAAAGATGTCAGGTACATAACATAAAACAGATTGGGAATTTATTGTTTCCAAAGGGCATGGCCTTCCTTAGCATCAGTTTGAAGCTTTT
GTTATGACTTAGCTGACTTGTGGCAGCGGGGCAAGCAAAAACAATAACACTGCTTATAAATGGCACCACATCTTGTTAACCTCCCCCCCAAATACTCTCT
GAAAGTCATGCACATACCTATGGGATTTTACACACCACCAGCTTAAAATGCTATGTCTCTATCCATCAGAAATAGTCATTATTCTATTTTTAAGGCAGCA
ACAAGAAAAGAAAAAACACTTTTCCTGAGGGATTTCTAACCATGTATCTAATCCTCCCATTTGGGCAGTATAGGTGTTTGCTTTTTTGTTTTCTTTTTTT
AAGAAAAACCTTGAAACCTTTGACACTGACAGATGTGTTTGCAAGGATACGGCTTCAGTATTACTAATTTCCATGTGTATCTGGAAGTATTTTTAAATGG
CATACCAAAATCCAGAAGTTTAAAGATGCCTATAAAAGTAAACAACATTTATTTAAAAAGAACTCTGAATATGCCTTCTTTTTTAATTAGAAATATCTTC
GAGACTTGGGTGTTTGTTAATAACTAATAACTGGAGTAAGCTACAGGATCTAAAGCAGCCCTTTTTACAGTCTAGTTAGGAGAGAGAAAATAATTGCAAA
TATCCACTTAGAGGCAAAGAACAATTTTTTATTATCAAAAAGGTTTCTGCACATTGTTGTGGCAATATTGTATCTGTTTAGAAAATGGGCTTTTCCAAAA
GCAAACAAAGATAGGTTCCTCAGGTGACCAAAACTGAAAATCAATATTTCCATGTTTCATTAATCAAGGCATAAAATACAATTAAAGCAAAATATTTTAC
ATTAAAA
  • refseq_CAST.F2 (forward primer)
  • refseq_CAST.R2 (reverse primer)
  • Exon skipping and alternative donor or acceptor

Frame 0

RKKQQASAAVNPPEPMLVEQPRPPRCQLPLVQP
ASLPV*IPQKPRPFQSANRWKDHIFLTRKNTKNR
L*KQNLRRSHSQPSCLWFMRKNPKKESQKNTQS
QKAYPSRHQIQEVTMLTIKKQFPDQLNSSHQRN
QQNQRLNHKT*FLLVERVLLVSLQYLASRVTRKK
KRNH*PQLCQLNLNRINHRESQAWMLLWMT**I
L*EDLKKLKKKIQRILDQKFQIQ*VPPT*RNWV
KEKSQFLQNIGNYWLKRKGSQGLLQTLRNP*GQM
ML*TPCHLTSPVGRLQLLERKLKKRNLQKF*KL
SQQGQSEVLLHPKRRKERWRRIQ*VIKHSRLCR
LHWAPGKQNLSSTSAQLRKSMRQKLKKKN*RSVV
RMMKQSHLSTD*NQPRIKMENHYCQSLKKNPSL
GVNQNSLMNFQKILTGLNVKRNHLSQLKRQKNL
RPLLQLLCRRLCVGPPCVVYSQHPLSRLP*RAQC
QMML*KPWLIAWGKRKQIQKMENL*WIKSRRRP
KKKTVKSLVKKKKQFLLIID*KRSRIKMESHSC
QKSLRNSFHP*VKTSFWMLCLRTSLVHKMLHLLN
LKMLNLLLPSLKWFPKPQLQRPKLEPHPVIPRR
VTKTSMMPWINSLTV*DKGSLTQMRTNQWKIK*
RKKLKLNIETSLEKEMTLSHLNTDISWMIMDRTN
Q*SHLQRNQRIQRNLQMTKTPLMLSQEIWTAVP
PLQKPHRTQQRISARRLLPAPKHLRMEVKRRIQ
QRQQRKLPSQKMTKEIQVKVSGICM*NLQLVDGD
F*RTKGFGNRKQLFWVISRMVFVESLNILNIGL
LFFSRKKMNLTGSPVY*VLINFEFF*LPSIGRE
SFIFVRNIFDKVS*SNTKKTKEKLSEFLHILHTV
PVNLICIFSLPLIFFVSV*KTMF*TFFSVLISY
YPLSSWAFELYLMLLWDNVYKSNIRYCTLGTYL
LLGC***INNR*PGQTRKHQTPFQFELFFARCED
FCILQSAQNTLRLESSQQQSKIKVR*VLV*QIS
SIRNKI*LILRVLI*LELCWFTVLVNCAFYYLY
IKPEQQLCL*SYCHISLCTV*RLALWNLSLPNIK
RNFCF*KNYIYILNLKPAFLPQQCKK*ALMSYH
FEWFSNILMNSS*TLH*YHRLEF*YLISSLFPG
RECRKRCQVHNIKQIGNLLFPKGMAFLSISLKLL
L*LS*LVAAGQAKTITLLINGTTSC*PPPQILS
ESHAHTYGILHTTSLKCYVSIHQK*SLFYF*GS
NKKRKNTFPEGFLTMYLILPFGQYRCLLFCFLFL
RKTLKPLTLTDVFARIRLQYY*FPCVSGSIFKW
HTKIQKFKDAYKSKQHLFKKNSEYAFFFN*KYL
RDLGVC**LITGVSYRI*SSPFYSLVRREKIIAN
IHLEAKNNFLLSKRFLHIVVAILYLFRKWAFPK
ANKDRFLR*PKLKINISMFH*SRHKIQLKQNIL
H*

Frame 1

EKSSKPRQQSILQNLCWWNSLGHQGVSFLWCNQ
QVFQYESHRNQGHSSQPTDGRTTSS*QEKTQKT
GCKNRT*EEVTVNQAVCGS*EKIPRRKAKRTHRA
KKPTQAGIRYRK*RCSQ*KSSFQIS*TAAIREI
NRTKD*TTRHDFCWWRECCWYHCNIWQAG*QEK
RKEIINPSCAS*I*TG*TIGKVRHGCCFG*LNRY
FRRT*RN*RRKYNVYWTRSFRSNEFHLHRGIG*
KRSHNSSKI*GTIG*KGRDHRASCRLFETHRAR
*CYRRLVI*LHLWVAYSCWKEN*KRGIYRSFKSS
VSRDSQKCCSTPREEKKGGEGYNE*SSTRGSVG
FTGHPASRT*ARPPLN*GSR*GKS*RRKTREVW
*G**NNPI*VQIKTSHG*RWKTTIARA*RKTQAS
E*IRTH**TFRRF*PV*M*RETI*AN*KDRRI*
GRCSSSCVGGCVSDLHV*YTVSTP*AGYLEGHS
AR*CCRSLG**PGEKGSRSRRWKTCDG*SQGEGQ
RRRP*KAW*KRRNNSS*L*IRRGQG*RWKATPA
KRV*GTASTHE*RLPSGCFV*GLLWSTKCFIS*
I*RC*TCCCHL*SGFPNPSFNDPSWSPTP*YLAE
*QRPR*CLG*TL*QSRTKAA*PR*EQTNGR*SK
GKS*S*T*RQAWRKR*HYPT*IQTSPG**WTGQ
TSEATYKEIRGFKETCR*PRPH*CSLRRSGQLSL
HYRNLTEHSKG*VQEGCFQLQST*EWR*SEGFS
KDNRGNFQAKR*LKKYKLRYLVSACKIFSWWMV
TFEEQKALATENNCSG*FLEWFLLSL*TS*ILVC
YSFPERK*I*LVHLCTEY**TLNFFNCLQLGEK
ALYL*EIYLIKFLKATPKKQKKS*VNFCTFYTQ
CL*ISFVFSVCP*FFLLVFRKQCFKHSSVF*FLI
TPFPLGLLNCI*CCFGIMFISQT*DIVHWAHIS
SWAANNKLITGNLDKPGSTKPLFSLNSSLPGVR
TSASYSQHRTH*DLNQVSNRAK*RLDKSLCSKFR
A*EIKSN*FLGYSSDLNSVGLLC**TVLSIIYT
*NLSSNCVFRAIATLAFALYSVWLYGT*VYQI*
KETSAFKKIIYIY*I*NLHFSHSNVRSRL*CPTT
LNGFLIS**IVPEHCTDIID*NFDI*FHLYFLV
ENAGKDVRYIT*NRLGIYCFQRAWPSLASV*SF
CYDLADLWQRGKQKQ*HCL*MAPHLVNLPPKYSL
KVMHIPMGFYTPPA*NAMSLSIRNSHYSIFKAA
TRKEKTLFLRDF*PCI*SSHLGSIGVCFFVFFF
*EKP*NL*H*QMCLQGYGFSITNFHVYLEVFLNG
IPKSRSLKMPIKVNNIYLKRTLNMPSFLIRNIF
ETWVFVNN**LE*ATGSKAALFTV*LGERK*LQ
IST*RQRTIFYYQKGFCTLLWQYCICLENGLFQK
QTKIGSSGDQN*KSIFPCFINQGIKYN*SKIFY
IK

Frame 2

KKAASLGSSQSSRTYAGGTASATKVSASSGATS
KSSSMNPTETKAIPVSQQMEGPHLPNKKKHKKQ
AVKTEPEKKSQSTKLSVVHEKKSQEGKPKEHTE
PKSLPKQASDTGSNDAHNKKAVSRSAEQQPSEKS
TEPKTKPQDMISAGGESVAGITAISGKPGDKKK
EKKSLTPAVPVESKPDKPSGKSGMDAALDDLID
TLGGPEETEEENTTYTGPEVSDPMSSTYIEELGK
REVTIPPKYRELLAKKEGITGPPADSSKPIGPD
DAIDALSSDFTCGSPTAAGKKTEKEESTEVLKA
QSAGTVRSAAPPQEKKRKVEKDTMSDQALEALSA
SLGTRQAEPELDLRSIKEVDEAKAKEEKLEKCG
EDDETIPSEYRLKPATDKDGKPLLPEPEEKPKP
RSESELIDELSEDFDRSECKEKPSKPTEKTEESK
AAAPAPVSEAVCRTSMCSIQSAPPEPATLKGTV
PDDAVEALADSLGKKEADPEDGKPVMDKVKEKA
KEEDREKLGEKEETIPPDYRLEEVKDKDGKPLLP
KESKEQLPPMSEDFLLDALSEDFSGPQNASSLK
FEDAKLAAAISEVVSQTPASTTQAGAPPRDTSQ
SDKDLDDALDKLSDSLGQRQPDPDENKPMEDKVK
EKAKAEHRDKLGERDDTIPPEYRHLLDDNGQDK
PVKPPTKKSEDSKKPADDQDPIDALSGDLDSCP
STTETSQNTAKDKCKKAASSSKAPKNGGKAKDSA
KTTEETSKPKDD*RNTS*GIWYLHVKSSAGGW*
LLKNKRLWQQKTIVLGDF*NGFC*VSEHPKYWF
VILFQKENEFDWFTCVLSIDKL*IFLIAFNWERK
LYICKKYI**SFLKQHQKNKRKAK*IFAHSTHS
ACKSHLYFQFALNFFC*CLENNVLNILQCSDFL
LPPFLLGF*TVFDVALG*CL*VKHKILYIGHISP
LGLLIIN**QVTWTNQEAPNPFSV*TLLCQV*G
LLHLTVSTEHTET*IKSATEQNKG*ISPCVANF
EHKK*NLINS*GTHLT*TLLVYCVSKLCFLLSIH
KT*AATVSLELLPH*PLHCIASGFMELKFTKYK
KKLLLLKKLYIYIKFETCISPTAM*EVGSDVLP
L*MVF*YLNE*FLNIALISSIRILIFNFIFISW*
RMQEKMSGT*HKTDWEFIVSKGHGLP*HQFEAF
VMT*LTCGSGASKNNNTAYKWHHILLTSPPNTL
*KSCTYLWDFTHHQLKMLCLYPSEIVIILFLRQQ
QEKKKHFS*GISNHVSNPPIWAV*VFAFLFSFF
KKNLETFDTDRCVCKDTASVLLISMCIWKYF*M
AYQNPEV*RCL*K*TTFI*KEL*ICLLF*LEISS
RLGCLLITNNWSKLQDLKQPFLQSS*ERENNCK
YPLRGKEQFFIIKKVSAHCCGNIVSV*KMGFSK
SKQR*VPQVTKTENQYFHVSLIKA*NTIKAKYFT
LK

Sequence NM_173061

AGAACCTGAGCTCGACCTCCGCTCAATTAAGGAAGTCGATGAGGGGGGAGTCTCCCTGACTTCCAGCAACAATCCTTGAGTCTGGGACTGCCCTGGCCTA
AGATGGGCCAGTTTCTATCTTCGACTTTCTTGGAGGGCTCACCGGCCACAGTGTGGCACGATAAGCTTTGTGACGGTGAACGCAGAGGAGCAAGAGAAGC
AGTTCGTATCTTCCAGGACCAAGCAAAAGCTAAAGAAGAAAAACTAGAGAAGTGTGGTGAGGATGATGAAACAATCCCATCTGAGTACAGATTAAAACCA
GCCACGGATAAAGATGGAAAACCACTATTGCCAGAGCCTGAAGAAAAACCCAAGCCTCGGAGTGAATCAGAACTCATTGATGAACTTTCAGAAGATTTTG
ACCGGTCTGAATGTAAAGAGAAACCATCTAAGCCAACTGAAAAGACAGAAGAATCTAAGGCCGCTGCTCCAGCTCCTGTGTCGGAGGCTGTGTGTCGGAC
CTCCATGTGTAGTATACAGTCAGCACCCCCTGAGCCGGCTACCTTGAAGGGCACAGTGCCAGATGATGCTGTAGAAGCCTTGGCTGATAGCCTGGGGAAA
AAGGAAGCAGATCCAGAAGATGGAAAACCTGTGATGGATAAAGTCAAGGAGAAGGCCAAAGAAGAAGACCGTGAAAAGCTTGGTGAAAAAGAAGAAACAA
TTCCTCCTGATTATAGATTAGAAGAGGTCAAGGATAAAGATGGAAAGCCACTCCTGCCAAAAGAGTCTAAGGAACAGCTTCCACCCATGAGTGAAGACTT
CCTTCTGGATGCTTTGTCTGAGGACTTCTCTGGTCCACAAAATGCTTCATCTCTTAAATTTGAAGATGCTAAACTTGCTGCTGCCATCTCTGAAGTGGTT
TCCCAAACCCCAGCTTCAACGACCCAAGCTGGAGCCCCACCCCGTGATACCTCGAGTGACAAAGACCTCGATGATGCCTTGGATAAACTCTCTGACAGTC
TAGGACAAAGGCAGCCTGACCCAGATGAGAACAAACCAATGGAAGATAAAGTAAAGGAAAAAGCTAAAGCTGAACATAGAGACAAGCTTGGAGAAAGAGA
TGACACTATCCCACCTGAATACAGACATCTCCTGGATGATAATGGACAGGACAAACCAGTGAAGCCACCTACAAAGAAATCAGAGGATTCAAAGAAACCT
GCAGATGACCAAGACCCCATTGATGCTCTCTCAGGAGATCTGGACAGCTGTCCCTCCACTACAGAAACCTCACAGAACACAGCAAAGGATAAGTGCAAGA
AGGCTGCTTCCAGCTCCAAAGCACCTAAGAATGGAGGTAAAGCGAAGGATTCAGCAAAGACAACAGAGGAAACTTCCAAGCCAAAAGATGACTAAAGAAA
TACAAGTTAAGGTATCTGGTATCTGCATGTAAAATCTTCAGCTGGTGGATGGTGACTTTTGAAGAACAAAAGGCTTTGGCAACAGAAAACAATTGTTCTG
GGTGATTTCTAGAATGGTTTTTGTTGAGTCTCTGAACATCCTAAATATTGGTTTGTTATTCTTTTCCAGAAAGAAAATGAATTTGACTGGTTCACCTGTG
TACTGAGTATTGATAAACTTTGAATTTTTTTAATTGCCTTCAATTGGGAGAGAAAGCTTTATATTTGTGTGAGGACTTCTGCATCTTACAGTCAGCACAG
AACACACTGAGACTTGAATCAAGTCAGCAACAGAGCAAAATAAAGGTTAGATAAGTCCTTGTGTAGCAAATTTCGAGCATAAGAAATAAAATCTAATTAA
TTCTTAGGGTACTCATCTGACTTGAACTCTGTTGGTTTACTGTGTTAGTAAACTGTGCTTTCTATTATCTATACATAAAACCTGAGCAGCAACTGTGTCT
TTAGAGCTATTGCCACATTAGCCTTTGCACTGTATAGCGTCTGGCTTTATGGAACTTAAGTTTACCAAATATAAAAAGAAACTTCTGCTTTTAAAAAAAT
TATATATATATATTAAATTTGAAACCTGCATTTCTCCCACAGCAATGTAAGAAGTAGGCTCTGATGTCCTACCACTTTGAATGGTTTTCTAATATCTTAA
TGAATAGTTCCTGAACATTGCACTGATATCATCGATTAGAATTTTGATATTTAATTTCATCTTTATTTCCTGGTAGAGAATGCAGGAAAAGATGTCAGGT
ACATAACATAAAACAGATTGGGAATTTATTGTTTCCAAAGGGCATGGCCTTCCTTAGCATCAGTTTGAAGCTTTTGTTATGACTTAGCTGACTTGTGGCA
GCGGGGCAAGCAAAAACAATAACACTGCTTATAAATGGCACCACATCTTGTTAACCTCCCCCCCAAATACTCTCTGAAAGTCATGCACATACCTATGGGA
TTTTACACACCACCAGCTTAAAATGCTATGTCTCTATCCATCAGAAATAGTCATTATTCTATTTTTAAGGCAGCAACAAGAAAAGAAAAAACACTTTTCC
TGAGGGATTTCTAACCATGTATCTAATCCTCCCATTTGGGCAGTATAGGTGTTTGCTTTTTTGTTTTCTTTTTTTAAGAAAAACCTTGAAACCTTTGACA
CTGACAGATGTGTTTGCAAGGATACGGCTTCAGTATTACTAATTTCCATGTGTATCTGGAAGTATTTTTAAATGGCATACCAAAATCCAGAAGTTTAAAG
ATGCCTATAAAAGTAAACAACATTTATTTAAAAAGAACTCTGAATATGCCTTCTTTTTTAATTAGAAATATCTTCGAGACTTGGGTGTTTGTTAATAACT
AATAACTGGAGTAAGCTACAGGATCTAAAGCAGCCCTTTTTACAGTCTAGTTAGGAGAGAGAAAATAATTGCAAATATCCACTTAGAGGCAAAGAACAAT
TTTTTATTATCAAAAAGGTTTCTGCACATTGTTGTGGCAATATTGTATCTGTTTAGAAAATGGGCTTTTCCAAAAGCAAACAAAGATAGGTTCCTCAGGT
GACCAAAACTGAAAATCAATATTTCCATGTTTCATTAATCAAGGCATAAAATACAATTAAAGCAAAATATTTTACATTAAAA
  • refseq_CAST.F2 (forward primer)
  • refseq_CAST.R2 (reverse primer)
  • Exon skipping and alternative donor or acceptor

Frame 0

RT*ARPPLN*GSR*GGSLPDFQQQSLSLGLPWP
KMGQFLSSTFLEGSPATVWHDKLCDGERRGAREA
VRIFQDQAKAKEEKLEKCGEDDETIPSEYRLKP
ATDKDGKPLLPEPEEKPKPRSESELIDELSEDF
DRSECKEKPSKPTEKTEESKAAAPAPVSEAVCRT
SMCSIQSAPPEPATLKGTVPDDAVEALADSLGK
KEADPEDGKPVMDKVKEKAKEEDREKLGEKEET
IPPDYRLEEVKDKDGKPLLPKESKEQLPPMSEDF
LLDALSEDFSGPQNASSLKFEDAKLAAAISEVV
SQTPASTTQAGAPPRDTSSDKDLDDALDKLSDS
LGQRQPDPDENKPMEDKVKEKAKAEHRDKLGERD
DTIPPEYRHLLDDNGQDKPVKPPTKKSEDSKKP
ADDQDPIDALSGDLDSCPSTTETSQNTAKDKCK
KAASSSKAPKNGGKAKDSAKTTEETSKPKDD*RN
TS*GIWYLHVKSSAGGW*LLKNKRLWQQKTIVL
GDF*NGFC*VSEHPKYWFVILFQKENEFDWFTC
VLSIDKL*IFLIAFNWERKLYICVRTSASYSQHR
TH*DLNQVSNRAK*RLDKSLCSKFRA*EIKSN*
FLGYSSDLNSVGLLC**TVLSIIYT*NLSSNCV
FRAIATLAFALYSVWLYGT*VYQI*KETSAFKKI
IYIY*I*NLHFSHSNVRSRL*CPTTLNGFLIS*
*IVPEHCTDIID*NFDI*FHLYFLVENAGKDVR
YIT*NRLGIYCFQRAWPSLASV*SFCYDLADLWQ
RGKQKQ*HCL*MAPHLVNLPPKYSLKVMHIPMG
FYTPPA*NAMSLSIRNSHYSIFKAATRKEKTLF
LRDF*PCI*SSHLGSIGVCFFVFFF*EKP*NL*H
*QMCLQGYGFSITNFHVYLEVFLNGIPKSRSLK
MPIKVNNIYLKRTLNMPSFLIRNIFETWVFVNN
**LE*ATGSKAALFTV*LGERK*LQIST*RQRTI
FYYQKGFCTLLWQYCICLENGLFQKQTKIGSSG
DQN*KSIFPCFINQGIKYN*SKIFYIK

Frame 1

EPELDLRSIKEVDEGGVSLTSSNNP*VWDCPGL
RWASFYLRLSWRAHRPQCGTISFVTVNAEEQEK
QFVSSRTKQKLKKKN*RSVVRMMKQSHLSTD*NQ
PRIKMENHYCQSLKKNPSLGVNQNSLMNFQKIL
TGLNVKRNHLSQLKRQKNLRPLLQLLCRRLCVG
PPCVVYSQHPLSRLP*RAQCQMML*KPWLIAWGK
RKQIQKMENL*WIKSRRRPKKKTVKSLVKKKKQ
FLLIID*KRSRIKMESHSCQKSLRNSFHP*VKT
SFWMLCLRTSLVHKMLHLLNLKMLNLLLPSLKWF
PKPQLQRPKLEPHPVIPRVTKTSMMPWINSLTV
*DKGSLTQMRTNQWKIK*RKKLKLNIETSLEKE
MTLSHLNTDISWMIMDRTNQ*SHLQRNQRIQRNL
QMTKTPLMLSQEIWTAVPPLQKPHRTQQRISAR
RLLPAPKHLRMEVKRRIQQRQQRKLPSQKMTKE
IQVKVSGICM*NLQLVDGDF*RTKGFGNRKQLFW
VISRMVFVESLNILNIGLLFFSRKKMNLTGSPV
Y*VLINFEFF*LPSIGRESFIFV*GLLHLTVST
EHTET*IKSATEQNKG*ISPCVANFEHKK*NLIN
S*GTHLT*TLLVYCVSKLCFLLSIHKT*AATVS
LELLPH*PLHCIASGFMELKFTKYKKKLLLLKK
LYIYIKFETCISPTAM*EVGSDVLPL*MVF*YLN
E*FLNIALISSIRILIFNFIFISW*RMQEKMSG
T*HKTDWEFIVSKGHGLP*HQFEAFVMT*LTCG
SGASKNNNTAYKWHHILLTSPPNTL*KSCTYLWD
FTHHQLKMLCLYPSEIVIILFLRQQQEKKKHFS
*GISNHVSNPPIWAV*VFAFLFSFFKKNLETFD
TDRCVCKDTASVLLISMCIWKYF*MAYQNPEV*R
CL*K*TTFI*KEL*ICLLF*LEISSRLGCLLIT
NNWSKLQDLKQPFLQSS*ERENNCKYPLRGKEQ
FFIIKKVSAHCCGNIVSV*KMGFSKSKQR*VPQV
TKTENQYFHVSLIKA*NTIKAKYFTLK

Frame 2

NLSSTSAQLRKSMRGESP*LPATILESGTALA*
DGPVSIFDFLGGLTGHSVAR*AL*R*TQRSKRS
SSYLPGPSKS*RRKTREVW*G**NNPI*VQIKT
SHG*RWKTTIARA*RKTQASE*IRTH**TFRRF*
PV*M*RETI*AN*KDRRI*GRCSSSCVGGCVSD
LHV*YTVSTP*AGYLEGHSAR*CCRSLG**PGE
KGSRSRRWKTCDG*SQGEGQRRRP*KAW*KRRNN
SS*L*IRRGQG*RWKATPAKRV*GTASTHE*RL
PSGCFV*GLLWSTKCFIS*I*RC*TCCCHL*SG
FPNPSFNDPSWSPTP*YLE*QRPR*CLG*TL*QS
RTKAA*PR*EQTNGR*SKGKS*S*T*RQAWRKR
*HYPT*IQTSPG**WTGQTSEATYKEIRGFKET
CR*PRPH*CSLRRSGQLSLHYRNLTEHSKG*VQE
GCFQLQST*EWR*SEGFSKDNRGNFQAKR*LKK
YKLRYLVSACKIFSWWMVTFEEQKALATENNCS
G*FLEWFLLSL*TS*ILVCYSFPERK*I*LVHLC
TEY**TLNFFNCLQLGEKALYLCEDFCILQSAQ
NTLRLESSQQQSKIKVR*VLV*QISSIRNKI*L
ILRVLI*LELCWFTVLVNCAFYYLYIKPEQQLCL
*SYCHISLCTV*RLALWNLSLPNIKRNFCF*KN
YIYILNLKPAFLPQQCKK*ALMSYHFEWFSNIL
MNSS*TLH*YHRLEF*YLISSLFPGRECRKRCQV
HNIKQIGNLLFPKGMAFLSISLKLLL*LS*LVA
AGQAKTITLLINGTTSC*PPPQILSESHAHTYG
ILHTTSLKCYVSIHQK*SLFYF*GSNKKRKNTFP
EGFLTMYLILPFGQYRCLLFCFLFLRKTLKPLT
LTDVFARIRLQYY*FPCVSGSIFKWHTKIQKFK
DAYKSKQHLFKKNSEYAFFFN*KYLRDLGVC**L
ITGVSYRI*SSPFYSLVRREKIIANIHLEAKNN
FLLSKRFLHIVVAILYLFRKWAFPKANKDRFLR
*PKLKINISMFH*SRHKIQLKQNILH*

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